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Overview

ID MAG00627
Name CSH3_bin.19
Sample SMP0015
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species SM1-50 sp025457885
Assembly information
Completeness (%) 73.8
Contamination (%) 2.85
GC content (%) 45.0
N50 (bp) 20,136
Genome size (bp) 1,400,693

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1195

Gene name Description KEGG GOs EC E-value Score Sequence
CSH3_k127_1209740_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 452.0
CSH3_k127_1209740_1 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 423.0
CSH3_k127_1209740_2 Glycogen debranching enzyme N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 428.0
CSH3_k127_1210021_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 298.0
CSH3_k127_1210021_1 PFAM type II secretion system K07333 - - 0.00000000000000000000000002174 125.0
CSH3_k127_1210021_2 PFAM PKD domain containing protein - - - 0.0000000000002735 80.0
CSH3_k127_1210021_3 PKD domain containing protein - - - 0.00000003399 60.0
CSH3_k127_1364040_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000111 118.0
CSH3_k127_1364040_1 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.0000000494 66.0
CSH3_k127_1364040_2 helix_turn_helix ASNC type K03719 - - 0.00001511 54.0
CSH3_k127_1401797_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 522.0
CSH3_k127_1401797_1 Oxidoreductase NAD-binding domain protein K13016 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 456.0
CSH3_k127_1401797_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 396.0
CSH3_k127_1401797_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 387.0
CSH3_k127_1401797_4 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001049 233.0
CSH3_k127_1401797_5 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000003496 225.0
CSH3_k127_1401797_6 Oxidoreductase family, C-terminal alpha/beta domain K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000001173 166.0
CSH3_k127_1401797_7 Succinoglycan biosynthesis protein exoa - - - 0.00000000000000000000000000000000000281 150.0
CSH3_k127_1401797_8 COG0451 Nucleoside-diphosphate-sugar epimerases K01784 - 5.1.3.2 0.0000000000000000000000000000005324 124.0
CSH3_k127_1475331_0 leucyl-tRNA aminoacylation K01869 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 539.0
CSH3_k127_1475331_1 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.0000000000000000000000000000000000000004045 154.0
CSH3_k127_1475331_3 PQQ enzyme repeat - - - 0.000000000003964 81.0
CSH3_k127_1559185_0 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000005688 211.0
CSH3_k127_1559185_1 - - - - 0.0000000000000000000000000000000000000000000000000003629 186.0
CSH3_k127_1559185_2 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000005635 182.0
CSH3_k127_1559185_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000364 177.0
CSH3_k127_1559185_4 Protein of unknown function (DUF3795) - - - 0.00000000000001051 79.0
CSH3_k127_1585582_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 4.834e-309 961.0
CSH3_k127_1585582_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 470.0
CSH3_k127_1585582_10 Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000003373 221.0
CSH3_k127_1585582_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000004604 211.0
CSH3_k127_1585582_12 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000004791 181.0
CSH3_k127_1585582_13 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000000000113 186.0
CSH3_k127_1585582_14 SMART Excinuclease ABC, C subunit - - - 0.000000000000000000000000000000000001179 143.0
CSH3_k127_1585582_15 Membrane transport protein K07088 - - 0.0000000000000000000000000004646 115.0
CSH3_k127_1585582_16 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000009116 101.0
CSH3_k127_1585582_17 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000006966 91.0
CSH3_k127_1585582_18 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.00000000000000004348 85.0
CSH3_k127_1585582_19 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000001395 78.0
CSH3_k127_1585582_2 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 382.0
CSH3_k127_1585582_20 sequence-specific DNA binding K07108 - - 0.00000000000003244 76.0
CSH3_k127_1585582_21 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00003737 50.0
CSH3_k127_1585582_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 366.0
CSH3_k127_1585582_4 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 320.0
CSH3_k127_1585582_5 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 306.0
CSH3_k127_1585582_6 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
CSH3_k127_1585582_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
CSH3_k127_1585582_8 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009267 297.0
CSH3_k127_1585582_9 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001812 271.0
CSH3_k127_1651966_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 401.0
CSH3_k127_1651966_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 317.0
CSH3_k127_1651966_10 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
CSH3_k127_1651966_11 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000001975 233.0
CSH3_k127_1651966_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005008 198.0
CSH3_k127_1651966_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000008947 183.0
CSH3_k127_1651966_14 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001548 183.0
CSH3_k127_1651966_15 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000006319 184.0
CSH3_k127_1651966_16 BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000414 176.0
CSH3_k127_1651966_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000001599 170.0
CSH3_k127_1651966_18 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000009704 169.0
CSH3_k127_1651966_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001183 170.0
CSH3_k127_1651966_2 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 304.0
CSH3_k127_1651966_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000009504 161.0
CSH3_k127_1651966_21 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000002581 146.0
CSH3_k127_1651966_22 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001048 145.0
CSH3_k127_1651966_23 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000004054 145.0
CSH3_k127_1651966_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000002883 139.0
CSH3_k127_1651966_25 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005211 107.0
CSH3_k127_1651966_26 Ribosomal protein L23 K02892 - - 0.000000000000000003227 89.0
CSH3_k127_1651966_27 ribosomal protein S14 K02954 - - 0.00000000000000000362 84.0
CSH3_k127_1651966_28 Ribosomal L29 protein K02904 - - 0.00000000000000003935 82.0
CSH3_k127_1651966_29 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000001653 81.0
CSH3_k127_1651966_3 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 298.0
CSH3_k127_1651966_30 COG2002 Regulators of stationary sporulation gene expression - - - 0.000000001448 60.0
CSH3_k127_1651966_31 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000001984 53.0
CSH3_k127_1651966_4 Pheromone shutdown protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
CSH3_k127_1651966_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
CSH3_k127_1651966_6 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002181 261.0
CSH3_k127_1651966_7 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001654 261.0
CSH3_k127_1651966_8 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003939 259.0
CSH3_k127_1651966_9 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004828 256.0
CSH3_k127_1677069_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000001678 153.0
CSH3_k127_1677069_1 Sulfotransferase family - - - 0.00000000003078 64.0
CSH3_k127_1677069_2 deoxyribonucleoside 5'-monophosphate N-glycosidase activity K09457 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 1.7.1.13 0.000004152 55.0
CSH3_k127_171285_0 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003941 294.0
CSH3_k127_171285_1 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000002406 241.0
CSH3_k127_171285_2 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.00000000000000000000000000000000000000000000000001011 200.0
CSH3_k127_171285_3 FAD linked oxidase domain protein - - - 0.000000002118 62.0
CSH3_k127_171285_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001447 61.0
CSH3_k127_171285_5 SCP-2 sterol transfer family - - - 0.0003772 48.0
CSH3_k127_1744556_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 413.0
CSH3_k127_1744556_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 389.0
CSH3_k127_1744556_10 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000003888 78.0
CSH3_k127_1744556_11 PFAM PKD domain containing protein - - - 0.0000000004954 70.0
CSH3_k127_1744556_12 alpha beta - - - 0.0000001273 63.0
CSH3_k127_1744556_13 - - - - 0.0000004251 58.0
CSH3_k127_1744556_14 transcriptional regulator K05800 - - 0.00000898 54.0
CSH3_k127_1744556_15 Autotransporter beta-domain - - - 0.00002215 55.0
CSH3_k127_1744556_16 Protein of unknown function (DUF2510) - - - 0.0000754 52.0
CSH3_k127_1744556_17 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001023 50.0
CSH3_k127_1744556_18 cellulase activity - - - 0.0001524 55.0
CSH3_k127_1744556_19 AsnC-type helix-turn-helix domain - - - 0.0005125 49.0
CSH3_k127_1744556_2 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 317.0
CSH3_k127_1744556_20 Ferritin-like domain - - - 0.000791 51.0
CSH3_k127_1744556_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000001588 224.0
CSH3_k127_1744556_4 - K03561,K12287 - - 0.000000000000000000000000000000000000000000002232 188.0
CSH3_k127_1744556_5 Protein of unknown function (DUF1349) - - - 0.00000000000000000000000000002305 137.0
CSH3_k127_1744556_6 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000002528 115.0
CSH3_k127_1744556_7 double-strand break repair K01867,K09946 - 6.1.1.2 0.000000000000000004003 87.0
CSH3_k127_1744556_8 parallel beta-helix repeat K03671 - - 0.0000000000000002777 91.0
CSH3_k127_1744556_9 bacterial-type flagellum-dependent cell motility K01278,K02388,K02396,K03561,K12287 - 3.4.14.5 0.00000000000002417 85.0
CSH3_k127_1796847_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 379.0
CSH3_k127_1796847_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 379.0
CSH3_k127_1796847_2 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 377.0
CSH3_k127_1796847_3 Asparaginase, N-terminal K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000003144 229.0
CSH3_k127_1796847_4 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000004216 202.0
CSH3_k127_1796847_5 Thrombospondin type 3 - - - 0.000000000000000000000001453 116.0
CSH3_k127_1796847_6 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000002427 111.0
CSH3_k127_1796847_7 PKD domain containing protein - - - 0.00000000000001092 88.0
CSH3_k127_1796847_8 Polymorphic membrane protein, Chlamydia - - - 0.00000000004356 74.0
CSH3_k127_1796847_9 SpoVT / AbrB like domain - - - 0.0000000004272 63.0
CSH3_k127_187437_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 439.0
CSH3_k127_187437_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 348.0
CSH3_k127_187437_10 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000005066 190.0
CSH3_k127_187437_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000009595 179.0
CSH3_k127_187437_12 NUDIX domain - - - 0.00000000000000000000000000000000002645 139.0
CSH3_k127_187437_13 AraC-like ligand binding domain - - - 0.000000000000000000000000000002722 124.0
CSH3_k127_187437_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000003726 127.0
CSH3_k127_187437_15 - - - - 0.0000000000000000000000001747 112.0
CSH3_k127_187437_16 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000005619 92.0
CSH3_k127_187437_17 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000033 82.0
CSH3_k127_187437_18 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000001529 73.0
CSH3_k127_187437_19 glucose sorbosone - - - 0.00000004289 63.0
CSH3_k127_187437_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 349.0
CSH3_k127_187437_3 Hydrogenase expression formation protein (HypD) K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 295.0
CSH3_k127_187437_4 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004236 252.0
CSH3_k127_187437_5 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000008512 237.0
CSH3_k127_187437_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000004147 228.0
CSH3_k127_187437_7 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000022 211.0
CSH3_k127_187437_8 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.00000000000000000000000000000000000000000000000000000000002402 212.0
CSH3_k127_187437_9 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000007773 215.0
CSH3_k127_1946835_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 308.0
CSH3_k127_1946835_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000002909 270.0
CSH3_k127_1946835_2 Uncharacterised protein - - - 0.00001562 57.0
CSH3_k127_1948935_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 460.0
CSH3_k127_1948935_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
CSH3_k127_1948935_2 Belongs to the UPF0200 family - - - 0.0000000000000000000000000000000000000000000000423 176.0
CSH3_k127_1948935_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000005488 89.0
CSH3_k127_1948935_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000001803 78.0
CSH3_k127_1960063_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.069e-245 779.0
CSH3_k127_1960063_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 440.0
CSH3_k127_1960063_10 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002898 243.0
CSH3_k127_1960063_11 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000003692 232.0
CSH3_k127_1960063_12 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000356 229.0
CSH3_k127_1960063_13 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000004736 181.0
CSH3_k127_1960063_14 Pfam:KaiC - - - 0.0000000000000000000000000000001234 134.0
CSH3_k127_1960063_15 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000007304 138.0
CSH3_k127_1960063_16 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000003786 122.0
CSH3_k127_1960063_17 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000001899 102.0
CSH3_k127_1960063_18 Belongs to the glycosyl hydrolase 43 family K01278,K03561,K12287 - 3.4.14.5 0.00000000000000000003642 102.0
CSH3_k127_1960063_19 - - - - 0.00000000000000006615 83.0
CSH3_k127_1960063_2 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 414.0
CSH3_k127_1960063_20 - - - - 0.000000000000001929 82.0
CSH3_k127_1960063_21 lactoylglutathione lyase activity - - - 0.0000000001077 69.0
CSH3_k127_1960063_22 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.0000000563 66.0
CSH3_k127_1960063_23 Uncharacterised protein family UPF0058 - - - 0.0000001262 57.0
CSH3_k127_1960063_24 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000002471 63.0
CSH3_k127_1960063_25 Peptidase family C25 - - - 0.000007113 59.0
CSH3_k127_1960063_26 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00001363 54.0
CSH3_k127_1960063_3 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 362.0
CSH3_k127_1960063_4 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 354.0
CSH3_k127_1960063_5 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 312.0
CSH3_k127_1960063_6 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 307.0
CSH3_k127_1960063_7 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 310.0
CSH3_k127_1960063_8 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 292.0
CSH3_k127_1960063_9 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008273 282.0
CSH3_k127_1984657_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 9.29e-197 631.0
CSH3_k127_1984657_1 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 367.0
CSH3_k127_1984657_2 Belongs to the UPF0178 family - - - 0.000000000000000000000000000000000000000001518 159.0
CSH3_k127_2221825_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 2.201e-195 619.0
CSH3_k127_2221825_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000003081 184.0
CSH3_k127_2221825_2 - - - - 0.000000000000000000000000000000001449 136.0
CSH3_k127_2221825_3 polygalacturonase activity K13925 - - 0.000000000000206 83.0
CSH3_k127_2221825_4 6-phosphogluconolactonase activity - - - 0.0001245 54.0
CSH3_k127_2221825_5 metallopeptidase activity - - - 0.0003375 53.0
CSH3_k127_2573003_0 Caspase domain - - - 0.0000000000000000000000000000001004 136.0
CSH3_k127_2573003_1 Domain of unknown function (DUF5011) - - - 0.0000000000000000000000003335 116.0
CSH3_k127_2573003_2 thiolester hydrolase activity K01259,K06889,K21193 - 3.4.11.5 0.000000000000000000196 99.0
CSH3_k127_2573003_3 Psort location Cytoplasmic, score - - - 0.000000000000001616 86.0
CSH3_k127_2573003_4 glucose sorbosone - - - 0.0000000003647 72.0
CSH3_k127_2598302_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.772e-289 898.0
CSH3_k127_2602984_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 474.0
CSH3_k127_2602984_1 Radical SAM - - - 0.0000000000000000000000000000000000000117 154.0
CSH3_k127_2602984_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000004829 128.0
CSH3_k127_2602984_3 PFAM periplasmic copper-binding - - - 0.00000000000000000000002761 115.0
CSH3_k127_2602984_4 Parallel beta-helix - - - 0.00000000004642 76.0
CSH3_k127_2609230_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 507.0
CSH3_k127_2609230_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 463.0
CSH3_k127_2609230_10 - K07092 - - 0.00000000000000000000000000000000000000000000007008 171.0
CSH3_k127_2609230_11 Rubrerythrin - - - 0.000000000000000000000000000000000002059 145.0
CSH3_k127_2609230_12 redox protein regulator of disulfide bond formation - - - 0.00000000000000000000000000000001251 128.0
CSH3_k127_2609230_13 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000001217 131.0
CSH3_k127_2609230_14 Belongs to the Fur family K09825 - - 0.000000000000000000000000001247 117.0
CSH3_k127_2609230_15 protein conserved in archaea - - - 0.00000000000000000005605 93.0
CSH3_k127_2609230_17 - K03741 - 1.20.4.1 0.0000000000009053 74.0
CSH3_k127_2609230_18 PKD domain - - - 0.0000000003865 71.0
CSH3_k127_2609230_2 Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 304.0
CSH3_k127_2609230_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 306.0
CSH3_k127_2609230_4 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
CSH3_k127_2609230_5 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001385 247.0
CSH3_k127_2609230_6 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
CSH3_k127_2609230_7 Desulfoferrodoxin ferrous iron-binding domain K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000001705 196.0
CSH3_k127_2609230_8 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000001429 192.0
CSH3_k127_2609230_9 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000004069 196.0
CSH3_k127_2629454_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.47e-213 676.0
CSH3_k127_2629454_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 455.0
CSH3_k127_2629454_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000004906 158.0
CSH3_k127_2629454_11 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000000000000000000000436 162.0
CSH3_k127_2629454_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002192 148.0
CSH3_k127_2629454_13 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000404 147.0
CSH3_k127_2629454_14 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000007011 136.0
CSH3_k127_2629454_15 Transcriptional regulator - - - 0.000000000000000001081 95.0
CSH3_k127_2629454_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000001277 84.0
CSH3_k127_2629454_17 amine dehydrogenase activity - - - 0.000000000000007073 87.0
CSH3_k127_2629454_18 - - - - 0.00000000000001197 79.0
CSH3_k127_2629454_19 amine dehydrogenase activity - - - 0.00000000004091 76.0
CSH3_k127_2629454_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 301.0
CSH3_k127_2629454_21 Domain of unknown function (DUF4389) - - - 0.00001898 55.0
CSH3_k127_2629454_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003461 277.0
CSH3_k127_2629454_4 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000002 268.0
CSH3_k127_2629454_5 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 252.0
CSH3_k127_2629454_6 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004113 245.0
CSH3_k127_2629454_7 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.0000000000000000000000000000000000000000000000000000000004026 212.0
CSH3_k127_2629454_8 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000001321 214.0
CSH3_k127_2629454_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000001825 176.0
CSH3_k127_2630200_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 602.0
CSH3_k127_2630200_1 aminopeptidase K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 426.0
CSH3_k127_2630200_10 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000001837 118.0
CSH3_k127_2630200_11 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000005088 112.0
CSH3_k127_2630200_12 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.00000000000000000000000000542 123.0
CSH3_k127_2630200_13 aminopeptidase activity K05994 - 3.4.11.10 0.000000000000000000001067 109.0
CSH3_k127_2630200_14 response regulator, receiver K07668,K07669 - - 0.000000000000000000001901 98.0
CSH3_k127_2630200_15 Peptidase family M28 K04771 - 3.4.21.107 0.000000000000000000003299 107.0
CSH3_k127_2630200_16 Papain family cysteine protease - - - 0.00000000000000000004625 105.0
CSH3_k127_2630200_17 Propeptide_C25 - - - 0.0000000000000001238 94.0
CSH3_k127_2630200_18 PFAM Peptidase C1A, papain - - - 0.0000000000000008551 91.0
CSH3_k127_2630200_19 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000879 81.0
CSH3_k127_2630200_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 318.0
CSH3_k127_2630200_20 Sugar (and other) transporter K08196,K08369 - - 0.0000000001909 73.0
CSH3_k127_2630200_21 Lrp/AsnC ligand binding domain - - - 0.000000006327 59.0
CSH3_k127_2630200_22 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000008651 58.0
CSH3_k127_2630200_23 COG1522 Transcriptional regulators K03719 - - 0.0002641 50.0
CSH3_k127_2630200_24 Transglutaminase/protease-like homologues - - - 0.0009857 51.0
CSH3_k127_2630200_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002474 262.0
CSH3_k127_2630200_4 Pas domain - - - 0.000000000000000000000000000000000000000000000009625 183.0
CSH3_k127_2630200_5 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000619 172.0
CSH3_k127_2630200_6 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000006059 163.0
CSH3_k127_2630200_7 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000002484 167.0
CSH3_k127_2630200_8 NmrA-like family - - - 0.000000000000000000000000000000000005948 147.0
CSH3_k127_2630200_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000004057 140.0
CSH3_k127_263023_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
CSH3_k127_263023_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 362.0
CSH3_k127_263023_10 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000002064 91.0
CSH3_k127_263023_11 Glutaredoxin - - - 0.0000000000000001856 83.0
CSH3_k127_263023_12 - - - - 0.00000000001009 78.0
CSH3_k127_263023_13 - - - - 0.000008338 49.0
CSH3_k127_263023_14 PFAM PKD domain containing protein - - - 0.0001264 55.0
CSH3_k127_263023_2 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 340.0
CSH3_k127_263023_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002991 283.0
CSH3_k127_263023_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007118 271.0
CSH3_k127_263023_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000006579 258.0
CSH3_k127_263023_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003515 228.0
CSH3_k127_263023_7 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000009361 178.0
CSH3_k127_263023_8 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000001057 156.0
CSH3_k127_263023_9 Lrp/AsnC ligand binding domain - - - 0.0000000000000000002129 90.0
CSH3_k127_2643622_0 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 411.0
CSH3_k127_2643622_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002029 208.0
CSH3_k127_2643622_10 NmrA-like family - - - 0.0000000002229 68.0
CSH3_k127_2643622_11 PFAM conserved K07027 - - 0.0000000002347 72.0
CSH3_k127_2643622_12 Transglutaminase-like superfamily - - - 0.0000008118 61.0
CSH3_k127_2643622_13 Belongs to the peptidase S8 family - - - 0.0004478 54.0
CSH3_k127_2643622_2 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000006974 167.0
CSH3_k127_2643622_3 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000004129 185.0
CSH3_k127_2643622_4 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000001941 156.0
CSH3_k127_2643622_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000001662 133.0
CSH3_k127_2643622_6 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000001973 136.0
CSH3_k127_2643622_7 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000000000001414 98.0
CSH3_k127_2643622_8 protein contain chitin-binding domain type 3 - - - 0.0000000000000129 87.0
CSH3_k127_2643622_9 Archaeal Type IV pilin, N-terminal - - - 0.00000000000003346 86.0
CSH3_k127_2660653_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 432.0
CSH3_k127_2660653_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 421.0
CSH3_k127_2660653_10 K -dependent Na Ca K07301 - - 0.000000000000000000000000000000000000000000000004302 185.0
CSH3_k127_2660653_11 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000001561 168.0
CSH3_k127_2660653_12 - - - - 0.0000000000000000000000000000000001294 134.0
CSH3_k127_2660653_13 Cupin domain - - - 0.0000000000000000000000000000001809 128.0
CSH3_k127_2660653_14 - - - - 0.0000000000005538 75.0
CSH3_k127_2660653_15 Peptidase family C25 - - - 0.000000004641 68.0
CSH3_k127_2660653_16 Peptidase family C25 - - - 0.000001104 61.0
CSH3_k127_2660653_17 Putative zinc- or iron-chelating domain K06940 - - 0.000008012 50.0
CSH3_k127_2660653_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 307.0
CSH3_k127_2660653_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004346 271.0
CSH3_k127_2660653_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007241 259.0
CSH3_k127_2660653_5 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001189 245.0
CSH3_k127_2660653_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000003081 212.0
CSH3_k127_2660653_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000005855 203.0
CSH3_k127_2660653_8 CBS domain K03498 - - 0.0000000000000000000000000000000000000000000000001929 194.0
CSH3_k127_2660653_9 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000007584 184.0
CSH3_k127_2665310_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 532.0
CSH3_k127_2665310_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 469.0
CSH3_k127_2665310_2 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000001801 147.0
CSH3_k127_2665310_3 binds to the 23S rRNA K02921 - - 0.0000000000000000000000001655 108.0
CSH3_k127_2665310_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000009192 57.0
CSH3_k127_2665310_5 Transcription factor Pcc1 K09741 - - 0.0000005188 54.0
CSH3_k127_2665310_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000009839 48.0
CSH3_k127_2667813_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 540.0
CSH3_k127_2667813_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 531.0
CSH3_k127_2667813_10 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002693 270.0
CSH3_k127_2667813_11 GHMP kinases C terminal K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000007321 262.0
CSH3_k127_2667813_12 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000009049 253.0
CSH3_k127_2667813_13 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
CSH3_k127_2667813_14 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.0000000000000000000000000000000000000000000000000003358 197.0
CSH3_k127_2667813_15 methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000006759 196.0
CSH3_k127_2667813_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000003254 186.0
CSH3_k127_2667813_17 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000004844 149.0
CSH3_k127_2667813_18 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000009598 129.0
CSH3_k127_2667813_19 TIGRFAM mutator mutT protein K03574 - 3.6.1.55 0.00000000000000000000000004222 112.0
CSH3_k127_2667813_2 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 507.0
CSH3_k127_2667813_21 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000421 66.0
CSH3_k127_2667813_22 secreted hydrolase - - - 0.00000007673 64.0
CSH3_k127_2667813_3 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 497.0
CSH3_k127_2667813_4 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 467.0
CSH3_k127_2667813_5 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 466.0
CSH3_k127_2667813_6 resolution of meiotic recombination intermediates - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 462.0
CSH3_k127_2667813_7 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 299.0
CSH3_k127_2667813_8 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001505 281.0
CSH3_k127_2667813_9 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000953 275.0
CSH3_k127_270643_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.935e-212 691.0
CSH3_k127_270643_1 tRNA binding K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 497.0
CSH3_k127_270643_10 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00001629 48.0
CSH3_k127_270643_11 AsnC-type helix-turn-helix domain - - - 0.0008665 48.0
CSH3_k127_270643_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 429.0
CSH3_k127_270643_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 388.0
CSH3_k127_270643_4 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 359.0
CSH3_k127_270643_5 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000007499 237.0
CSH3_k127_270643_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000004777 207.0
CSH3_k127_270643_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000007183 72.0
CSH3_k127_270643_8 but it may be involved in stabilization of the trimeric complex - - - 0.000004884 52.0
CSH3_k127_270643_9 Peptidase family C25 - - - 0.00001384 57.0
CSH3_k127_2775343_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 478.0
CSH3_k127_2775343_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 361.0
CSH3_k127_2775343_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 336.0
CSH3_k127_2775343_3 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000001256 235.0
CSH3_k127_2775343_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000001455 220.0
CSH3_k127_2775343_5 PFAM LemA - - - 0.000000000000000000000000000000000000000000000000000000000001269 214.0
CSH3_k127_2775343_6 PFAM Radical SAM domain protein - - - 0.00000000000000000000000003535 111.0
CSH3_k127_2775343_7 Flavodoxin - - - 0.000000000131 68.0
CSH3_k127_2775343_8 - - - - 0.0006898 49.0
CSH3_k127_279803_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 452.0
CSH3_k127_279803_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 454.0
CSH3_k127_279803_10 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.000000000000000005618 90.0
CSH3_k127_279803_11 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000001176 73.0
CSH3_k127_279803_13 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000001919 57.0
CSH3_k127_279803_14 CAAX amino terminal protease family K07052 - - 0.000001085 59.0
CSH3_k127_279803_15 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0001929 48.0
CSH3_k127_279803_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 343.0
CSH3_k127_279803_3 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 331.0
CSH3_k127_279803_4 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 308.0
CSH3_k127_279803_5 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.00000000000000000000000000000000000000000000000000000000003011 208.0
CSH3_k127_279803_6 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000001009 231.0
CSH3_k127_279803_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000009819 195.0
CSH3_k127_279803_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000008401 96.0
CSH3_k127_279803_9 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.000000000000000001282 91.0
CSH3_k127_2809628_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 552.0
CSH3_k127_2809628_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 468.0
CSH3_k127_2809628_10 Lysine methyltransferase K02493 - 2.1.1.297 0.00000000000000000000000000000000006515 143.0
CSH3_k127_2809628_11 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000009284 139.0
CSH3_k127_2809628_12 - - - - 0.000000000000000000000000000001038 130.0
CSH3_k127_2809628_13 Peptidase family M50 - - - 0.0000000000000000000000000002516 123.0
CSH3_k127_2809628_14 OB-fold nucleic acid binding domain - - - 0.0000000000000000000000007804 116.0
CSH3_k127_2809628_15 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000004004 104.0
CSH3_k127_2809628_16 - - - - 0.0000000000000000001814 92.0
CSH3_k127_2809628_17 sequence-specific DNA binding K07108 - - 0.0000000000000871 75.0
CSH3_k127_2809628_18 Pectate lyase - - - 0.000000001887 71.0
CSH3_k127_2809628_19 thymidylate synthase K00560 - 2.1.1.45 0.0000001494 57.0
CSH3_k127_2809628_2 COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 342.0
CSH3_k127_2809628_20 protein contain chitin-binding domain type 3 K21606 - 3.2.1.202 0.000006588 59.0
CSH3_k127_2809628_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 275.0
CSH3_k127_2809628_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003141 265.0
CSH3_k127_2809628_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006131 267.0
CSH3_k127_2809628_6 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000001441 232.0
CSH3_k127_2809628_7 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000004361 194.0
CSH3_k127_2809628_8 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000001862 181.0
CSH3_k127_2809628_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000001106 171.0
CSH3_k127_2830694_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 486.0
CSH3_k127_2830694_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 353.0
CSH3_k127_2830694_10 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000001102 214.0
CSH3_k127_2830694_11 - - - - 0.0000000000000000000000000000000000000000000008276 167.0
CSH3_k127_2830694_12 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000002854 158.0
CSH3_k127_2830694_13 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000003816 160.0
CSH3_k127_2830694_14 4Fe-4S binding domain protein - - - 0.000000000000000000000000000000000000007143 156.0
CSH3_k127_2830694_15 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000007753 138.0
CSH3_k127_2830694_16 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000001233 138.0
CSH3_k127_2830694_17 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000005282 147.0
CSH3_k127_2830694_18 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000000001797 139.0
CSH3_k127_2830694_19 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000001301 121.0
CSH3_k127_2830694_2 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 355.0
CSH3_k127_2830694_20 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000001775 118.0
CSH3_k127_2830694_21 - - - - 0.000000000000000000000001196 108.0
CSH3_k127_2830694_22 membrane - - - 0.000000000000000000000004487 115.0
CSH3_k127_2830694_23 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000003933 104.0
CSH3_k127_2830694_24 Esterase PHB depolymerase - - - 0.000000000002199 67.0
CSH3_k127_2830694_25 Thioredoxin-like - - - 0.000000000004147 73.0
CSH3_k127_2830694_26 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000005429 67.0
CSH3_k127_2830694_27 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000002274 59.0
CSH3_k127_2830694_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 353.0
CSH3_k127_2830694_4 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 338.0
CSH3_k127_2830694_5 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 323.0
CSH3_k127_2830694_6 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 309.0
CSH3_k127_2830694_7 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 302.0
CSH3_k127_2830694_8 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 306.0
CSH3_k127_2830694_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007068 278.0
CSH3_k127_3158751_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 462.0
CSH3_k127_3158751_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 416.0
CSH3_k127_3158751_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000001502 74.0
CSH3_k127_3158751_11 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000006119 72.0
CSH3_k127_3158751_12 - - - - 0.000005307 51.0
CSH3_k127_3158751_2 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000001425 247.0
CSH3_k127_3158751_3 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001699 226.0
CSH3_k127_3158751_4 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000001588 166.0
CSH3_k127_3158751_5 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000000001393 151.0
CSH3_k127_3158751_6 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000005237 130.0
CSH3_k127_3158751_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000002465 108.0
CSH3_k127_3158751_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000002452 86.0
CSH3_k127_3158751_9 PFAM UspA domain protein - - - 0.000000000005943 71.0
CSH3_k127_3210577_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.808e-214 684.0
CSH3_k127_3210577_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 567.0
CSH3_k127_3210577_2 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 544.0
CSH3_k127_3210577_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 424.0
CSH3_k127_3210577_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000001332 201.0
CSH3_k127_3210577_5 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000251 173.0
CSH3_k127_3210577_6 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000002537 126.0
CSH3_k127_3210577_7 - - - - 0.0000000000000000000000002457 106.0
CSH3_k127_3210577_8 - - - - 0.0000001239 57.0
CSH3_k127_3312338_0 COG0058 Glucan phosphorylase - - - 7.351e-225 709.0
CSH3_k127_3312338_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 373.0
CSH3_k127_3312338_10 acid phosphatase activity - - - 0.00005168 56.0
CSH3_k127_3312338_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000009748 239.0
CSH3_k127_3312338_3 Glycogen debranching enzyme N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000001152 241.0
CSH3_k127_3312338_4 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000001624 189.0
CSH3_k127_3312338_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000001881 153.0
CSH3_k127_3312338_6 PFAM Peptidase C1A, papain - - - 0.0000000000000000767 95.0
CSH3_k127_3312338_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000001243 91.0
CSH3_k127_3312338_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000002327 82.0
CSH3_k127_3312338_9 helix_turn_helix ASNC type - - - 0.00000001655 66.0
CSH3_k127_3510962_0 PFAM type II secretion system protein E K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 479.0
CSH3_k127_3572281_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000004157 225.0
CSH3_k127_3572281_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000001098 206.0
CSH3_k127_3572281_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000002808 200.0
CSH3_k127_3582495_0 KH, type 1, domain K07041 - - 1.571e-260 816.0
CSH3_k127_3582495_1 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 445.0
CSH3_k127_3582495_2 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 339.0
CSH3_k127_3582495_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 307.0
CSH3_k127_3582495_4 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002054 286.0
CSH3_k127_3582495_5 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006865 274.0
CSH3_k127_3582495_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000207 241.0
CSH3_k127_3582495_7 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000162 205.0
CSH3_k127_3582495_8 cyclohydrolase K01746 - 4.3.1.4 0.0000000000000000000000000000000000000000000000000001426 192.0
CSH3_k127_3582495_9 Domain of unknown function (DUF2341) - - - 0.00004785 55.0
CSH3_k127_3633156_0 PKD domain containing protein - - - 0.00000000000003587 88.0
CSH3_k127_3633156_1 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.000003608 61.0
CSH3_k127_3698305_0 Psort location Cytoplasmic, score - - - 0.0 1421.0
CSH3_k127_3698305_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1182.0
CSH3_k127_3698305_10 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 463.0
CSH3_k127_3698305_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 403.0
CSH3_k127_3698305_12 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 352.0
CSH3_k127_3698305_13 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 308.0
CSH3_k127_3698305_14 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 301.0
CSH3_k127_3698305_15 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004353 278.0
CSH3_k127_3698305_16 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004042 277.0
CSH3_k127_3698305_17 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005442 262.0
CSH3_k127_3698305_18 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003773 258.0
CSH3_k127_3698305_19 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000005322 266.0
CSH3_k127_3698305_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 0.0 1165.0
CSH3_k127_3698305_20 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
CSH3_k127_3698305_21 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000001479 223.0
CSH3_k127_3698305_22 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000004477 216.0
CSH3_k127_3698305_23 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000005677 211.0
CSH3_k127_3698305_24 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000007081 218.0
CSH3_k127_3698305_25 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000004107 184.0
CSH3_k127_3698305_26 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000007573 149.0
CSH3_k127_3698305_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000004912 144.0
CSH3_k127_3698305_28 Participates in transcription termination K02600 - - 0.000000000000000000000000000006721 123.0
CSH3_k127_3698305_29 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000001803 115.0
CSH3_k127_3698305_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1029.0
CSH3_k127_3698305_30 binds to the 23S rRNA K02921 - - 0.0000000000000000000000001584 109.0
CSH3_k127_3698305_31 hydrogenase maturation protease K03605 - - 0.0000000000000000000000005791 111.0
CSH3_k127_3698305_32 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000004475 100.0
CSH3_k127_3698305_33 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000001334 97.0
CSH3_k127_3698305_34 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000002068 102.0
CSH3_k127_3698305_35 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000006164 98.0
CSH3_k127_3698305_36 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001054 87.0
CSH3_k127_3698305_37 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.0000000000000001436 82.0
CSH3_k127_3698305_38 PFAM Methyltransferase type 11 - - - 0.000000000006591 74.0
CSH3_k127_3698305_39 Transglutaminase/protease-like homologues - - - 0.000000002912 68.0
CSH3_k127_3698305_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.812e-212 676.0
CSH3_k127_3698305_40 Bacterial transferase hexapeptide - - - 0.000000006364 66.0
CSH3_k127_3698305_41 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000009192 57.0
CSH3_k127_3698305_42 Transcription factor Pcc1 K09741 - - 0.000001347 53.0
CSH3_k127_3698305_43 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00004167 49.0
CSH3_k127_3698305_44 PFAM transglutaminase domain protein - - - 0.0001088 54.0
CSH3_k127_3698305_5 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 7.612e-194 614.0
CSH3_k127_3698305_6 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 564.0
CSH3_k127_3698305_7 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 485.0
CSH3_k127_3698305_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 474.0
CSH3_k127_3698305_9 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 476.0
CSH3_k127_3718350_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 2.807e-196 622.0
CSH3_k127_3718350_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 444.0
CSH3_k127_3718350_2 HhH-GPD family K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000002489 241.0
CSH3_k127_3718350_3 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000001029 220.0
CSH3_k127_3718350_4 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000286 113.0
CSH3_k127_3746385_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 509.0
CSH3_k127_3746385_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 485.0
CSH3_k127_3746385_10 Protein of unknown function (DUF1614) - - - 0.00000000000000000000256 103.0
CSH3_k127_3746385_11 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000009833 93.0
CSH3_k127_3746385_12 ABC-type uncharacterized transport system - - - 0.000000003445 70.0
CSH3_k127_3746385_13 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000001392 55.0
CSH3_k127_3746385_15 antibiotic catabolic process K01406,K02414,K07004,K13277,K21449 - 3.4.24.40 0.00001262 59.0
CSH3_k127_3746385_16 COG1522 Transcriptional regulators - - - 0.00002778 55.0
CSH3_k127_3746385_17 S-layer homology domain - - - 0.00008091 54.0
CSH3_k127_3746385_18 Protein of unknown function DUF58 - - - 0.0001316 55.0
CSH3_k127_3746385_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 446.0
CSH3_k127_3746385_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 261.0
CSH3_k127_3746385_4 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000001462 235.0
CSH3_k127_3746385_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000003763 198.0
CSH3_k127_3746385_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000006443 167.0
CSH3_k127_3746385_7 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000001565 154.0
CSH3_k127_3746385_8 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000002829 144.0
CSH3_k127_3746385_9 archaeal coiled-coil protein - - - 0.000000000000000000000004556 113.0
CSH3_k127_3770194_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
CSH3_k127_3770194_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003826 266.0
CSH3_k127_3770194_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000000000000000000000000008388 172.0
CSH3_k127_3770194_3 Male sterility protein - - - 0.00000000000000000000000000000000000000000971 167.0
CSH3_k127_3770194_4 PFAM Radical SAM - - - 0.0000000000000000000000000000008916 126.0
CSH3_k127_3770194_5 PQ loop repeat K15383 - - 0.000000000000001388 79.0
CSH3_k127_3770194_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000007072 76.0
CSH3_k127_3770194_7 Radical SAM - - - 0.000000001045 70.0
CSH3_k127_3770194_8 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000002863 65.0
CSH3_k127_3770194_9 Nicotianamine synthase protein - - - 0.00001281 55.0
CSH3_k127_3805990_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1446.0
CSH3_k127_3805990_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.234e-298 926.0
CSH3_k127_3805990_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 615.0
CSH3_k127_3805990_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 338.0
CSH3_k127_3805990_4 ATPases associated with a variety of cellular activities K02003,K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002021 269.0
CSH3_k127_3805990_5 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000001297 229.0
CSH3_k127_3805990_6 PFAM helix-turn-helix HxlR type - - - 0.000000000000000000000000000000000000002258 149.0
CSH3_k127_3805990_7 Radical SAM - - - 0.00000000000000001277 84.0
CSH3_k127_3815811_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.828e-292 923.0
CSH3_k127_3815811_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.193e-272 852.0
CSH3_k127_3815811_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 592.0
CSH3_k127_3815811_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 323.0
CSH3_k127_3815811_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000005036 188.0
CSH3_k127_3838148_0 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000001102 93.0
CSH3_k127_3838148_1 integral membrane protein - - - 0.0000000000000004584 91.0
CSH3_k127_3838148_2 PFAM Peptidase C1A, papain - - - 0.000000000000001656 89.0
CSH3_k127_3838148_3 Protein of unknown function (DUF996) - - - 0.000000000001244 76.0
CSH3_k127_3838148_4 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.000005648 59.0
CSH3_k127_3838148_5 Flavodoxin K03809 - 1.6.5.2 0.00005527 51.0
CSH3_k127_3884162_0 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 573.0
CSH3_k127_3884162_1 PFAM Type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 540.0
CSH3_k127_3884162_10 PFAM Flagella accessory C family protein K07822 - - 0.00001111 56.0
CSH3_k127_3884162_2 PFAM Type II secretion system F domain K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001807 293.0
CSH3_k127_3884162_3 SMART AAA ATPase K07331 - - 0.0000000000000000000000000000000000000007402 156.0
CSH3_k127_3884162_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000003443 140.0
CSH3_k127_3884162_5 flagella protein K07327,K07328 - - 0.0000000000000000000007711 105.0
CSH3_k127_3884162_6 Archaebacterial flagellin K07330 - - 0.00000000000000000133 91.0
CSH3_k127_3884162_7 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000001037 70.0
CSH3_k127_3884162_8 Archaeal flagellar protein F K07329 - - 0.0000000005677 65.0
CSH3_k127_3884162_9 TIGRFAM Diguanylate cyclase - - - 0.000008277 56.0
CSH3_k127_3896335_0 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 417.0
CSH3_k127_3896335_1 PFAM PEGA domain - - - 0.00000000000000000000000000000000000003898 161.0
CSH3_k127_3896335_2 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000000004321 62.0
CSH3_k127_3896335_3 - - - - 0.000003529 51.0
CSH3_k127_393106_0 Chitin synthase K00752 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605,GO:0090609 2.4.1.212 0.00000000000000000000000000000000000000000000001536 178.0
CSH3_k127_393106_1 PFAM Peptidase C11, clostripain - - - 0.00000000000000000000000257 118.0
CSH3_k127_3935128_0 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 501.0
CSH3_k127_3935128_1 TIGRFAM Small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 399.0
CSH3_k127_3935128_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000257 224.0
CSH3_k127_3935128_11 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000005741 217.0
CSH3_k127_3935128_12 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000000000000004101 203.0
CSH3_k127_3935128_13 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000009164 147.0
CSH3_k127_3935128_14 Family of unknown function (DUF438) K09155 - - 0.0000000000000000000000000003161 119.0
CSH3_k127_3935128_15 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000004102 106.0
CSH3_k127_3935128_16 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000005337 96.0
CSH3_k127_3935128_17 Periplasmic copper-binding protein (NosD) - - - 0.00000000001384 78.0
CSH3_k127_3935128_18 oxidoreductase activity K07114,K12511 - - 0.0000000695 64.0
CSH3_k127_3935128_19 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000695 64.0
CSH3_k127_3935128_2 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 377.0
CSH3_k127_3935128_20 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001292 65.0
CSH3_k127_3935128_3 glutamine synthetase K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 344.0
CSH3_k127_3935128_4 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 338.0
CSH3_k127_3935128_5 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 334.0
CSH3_k127_3935128_6 Radical SAM domain protein K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 299.0
CSH3_k127_3935128_7 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 297.0
CSH3_k127_3935128_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
CSH3_k127_3935128_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000007625 242.0
CSH3_k127_3944203_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.661e-255 804.0
CSH3_k127_3944203_1 PFAM GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 450.0
CSH3_k127_3944203_10 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0002563 52.0
CSH3_k127_3944203_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 326.0
CSH3_k127_3944203_3 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000009127 240.0
CSH3_k127_3944203_4 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
CSH3_k127_3944203_5 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.000000000000000000000000000000000000000000000000002443 188.0
CSH3_k127_3944203_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000001038 197.0
CSH3_k127_3944203_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000002318 158.0
CSH3_k127_3944203_8 PFAM periplasmic copper-binding - - - 0.0000000000000000000000000007111 133.0
CSH3_k127_3944203_9 PAP2 superfamily - - - 0.00000000000000008238 90.0
CSH3_k127_4020247_0 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002133 250.0
CSH3_k127_4020247_1 Fibronectin type III domain protein K21571 - - 0.000000106 64.0
CSH3_k127_4020247_2 Thioredoxin K03671 - - 0.000000303 57.0
CSH3_k127_4020247_3 Belongs to the peptidase S8 family - - - 0.000003314 61.0
CSH3_k127_4020247_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000478 53.0
CSH3_k127_4235374_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 464.0
CSH3_k127_4235374_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 390.0
CSH3_k127_4235374_2 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 302.0
CSH3_k127_4235374_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 260.0
CSH3_k127_4235374_4 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000004016 190.0
CSH3_k127_4235374_5 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000002202 175.0
CSH3_k127_4235374_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000002095 159.0
CSH3_k127_4235374_7 hydroxylase K15746 - 1.14.15.24 0.00000000000000000000000000000000001148 140.0
CSH3_k127_4235374_8 Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000000000000003887 142.0
CSH3_k127_4235374_9 lycopene cyclase - - - 0.0000000000000000000000000002367 117.0
CSH3_k127_4376075_0 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000003546 171.0
CSH3_k127_4376075_1 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000003814 137.0
CSH3_k127_4376075_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000002602 111.0
CSH3_k127_4376075_3 EamA-like transporter family - - - 0.0000000000000000000001355 104.0
CSH3_k127_4376075_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000008191 88.0
CSH3_k127_4376075_5 - - - - 0.0000000000000007428 84.0
CSH3_k127_4376075_6 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000001439 70.0
CSH3_k127_4384420_0 coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 469.0
CSH3_k127_4384420_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 350.0
CSH3_k127_4384420_2 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 325.0
CSH3_k127_4384420_3 S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 K15450 - 2.1.1.282 0.0000000000000000000000000000000000002225 149.0
CSH3_k127_4485470_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 495.0
CSH3_k127_4485470_1 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 465.0
CSH3_k127_4485470_10 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003471 286.0
CSH3_k127_4485470_11 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
CSH3_k127_4485470_12 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
CSH3_k127_4485470_13 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003856 258.0
CSH3_k127_4485470_14 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000006607 249.0
CSH3_k127_4485470_15 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000001957 252.0
CSH3_k127_4485470_16 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000001278 258.0
CSH3_k127_4485470_17 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000002137 217.0
CSH3_k127_4485470_18 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000000000000000029 205.0
CSH3_k127_4485470_19 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000002991 199.0
CSH3_k127_4485470_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 467.0
CSH3_k127_4485470_20 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000006131 195.0
CSH3_k127_4485470_21 RNA-binding protein of the translin family K07477 - - 0.000000000000000000000000000000000000003981 155.0
CSH3_k127_4485470_22 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000000000000823 143.0
CSH3_k127_4485470_23 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000000455 132.0
CSH3_k127_4485470_24 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000004797 126.0
CSH3_k127_4485470_25 cluster protein-associated redox disulfide domain - - - 0.00000000000004272 76.0
CSH3_k127_4485470_26 Archaeal Type IV pilin, N-terminal - - - 0.000000000002501 80.0
CSH3_k127_4485470_27 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000001735 54.0
CSH3_k127_4485470_28 - - - - 0.00003552 53.0
CSH3_k127_4485470_29 parallel beta-helix repeat K03671 - - 0.0001461 47.0
CSH3_k127_4485470_3 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 456.0
CSH3_k127_4485470_30 helix_turn_helix ASNC type K03719 - - 0.0001824 51.0
CSH3_k127_4485470_4 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 432.0
CSH3_k127_4485470_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 352.0
CSH3_k127_4485470_6 Clp protease K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 341.0
CSH3_k127_4485470_7 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 316.0
CSH3_k127_4485470_8 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 294.0
CSH3_k127_4485470_9 COG1691 NCAIR mutase (PurE)-related K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 290.0
CSH3_k127_4486866_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1116.0
CSH3_k127_4486866_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000008411 228.0
CSH3_k127_4486866_2 DsrE/DsrF/DrsH-like family - - - 0.000000000000000004067 91.0
CSH3_k127_4486866_3 CrtC N-terminal lipocalin domain - - - 0.000000001776 71.0
CSH3_k127_4486866_4 - - - - 0.0007129 51.0
CSH3_k127_4512872_0 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 376.0
CSH3_k127_4512872_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 355.0
CSH3_k127_4512872_10 PFAM Nitroreductase - - - 0.00000006306 66.0
CSH3_k127_4512872_11 Rhomboid family - - - 0.000001108 61.0
CSH3_k127_4512872_12 EamA-like transporter family K08978 - - 0.00003515 55.0
CSH3_k127_4512872_13 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0002596 52.0
CSH3_k127_4512872_14 Domain of unknown function (DUF2341) - - - 0.0002779 53.0
CSH3_k127_4512872_2 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007388 279.0
CSH3_k127_4512872_3 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000002469 174.0
CSH3_k127_4512872_4 Methyl-transferase - - - 0.0000000000000000000000000000000000000000005604 167.0
CSH3_k127_4512872_5 Pfam matches to PF13186.1 SPASM, and to PF04055.16 Radical_SAM, and to PF13353.1 Fer4_12 - - - 0.00000000000000000000000000000004343 138.0
CSH3_k127_4512872_6 Belongs to the peptidase S8 family - - - 0.0000000000000000000001974 111.0
CSH3_k127_4512872_7 Nitroreductase family - - - 0.000000000006606 79.0
CSH3_k127_4512872_8 Peptidase family C25 - - - 0.000000003133 70.0
CSH3_k127_4512872_9 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000003932 70.0
CSH3_k127_4580100_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 7.419e-267 831.0
CSH3_k127_4580100_1 PFAM Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 402.0
CSH3_k127_4580100_10 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000004715 158.0
CSH3_k127_4580100_11 Protein of unknown function (DUF996) - - - 0.000000000000000000000000000000000000009824 152.0
CSH3_k127_4580100_12 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000001288 132.0
CSH3_k127_4580100_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000001262 110.0
CSH3_k127_4580100_14 Domain of unknown function (DUF4870) - - - 0.000000000000000000004393 96.0
CSH3_k127_4580100_15 - - - - 0.00000000000000001503 83.0
CSH3_k127_4580100_16 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000008395 81.0
CSH3_k127_4580100_17 PKD domain K19668 - 3.2.1.91 0.0000000000000004459 93.0
CSH3_k127_4580100_18 Domain of unknown function (DUF4382) - - - 0.00000000001069 72.0
CSH3_k127_4580100_19 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000005599 76.0
CSH3_k127_4580100_2 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 323.0
CSH3_k127_4580100_20 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.00000000006286 75.0
CSH3_k127_4580100_21 - - - - 0.00000005072 57.0
CSH3_k127_4580100_22 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000007835 66.0
CSH3_k127_4580100_23 EamA-like transporter family - - - 0.0001156 53.0
CSH3_k127_4580100_3 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 329.0
CSH3_k127_4580100_4 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 295.0
CSH3_k127_4580100_5 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 289.0
CSH3_k127_4580100_6 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007216 261.0
CSH3_k127_4580100_7 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000327 238.0
CSH3_k127_4580100_8 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000009921 242.0
CSH3_k127_4580100_9 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000002479 177.0
CSH3_k127_4611001_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 2.196e-201 651.0
CSH3_k127_4611001_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 456.0
CSH3_k127_4611001_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000006604 220.0
CSH3_k127_4615686_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 561.0
CSH3_k127_4615686_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 417.0
CSH3_k127_4615686_2 helicase superfamily c-terminal domain K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 369.0
CSH3_k127_4615686_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000001282 205.0
CSH3_k127_4615686_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000924 48.0
CSH3_k127_4775179_0 Aromatic amino acid lyase K01745 - 4.3.1.3 1.591e-263 819.0
CSH3_k127_4775179_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.182e-225 711.0
CSH3_k127_4775179_2 Radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
CSH3_k127_4775179_3 Peptidase family M28 - - - 0.0000000000000000000000003293 120.0
CSH3_k127_4775179_4 snRNP Sm proteins K04796 - - 0.000000000000000007554 85.0
CSH3_k127_4775179_5 PFAM Peptidase C1A, papain - - - 0.00000000005645 74.0
CSH3_k127_4783622_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 7.846e-195 624.0
CSH3_k127_4783622_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000006741 248.0
CSH3_k127_4783622_2 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000004241 193.0
CSH3_k127_4802500_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002786 274.0
CSH3_k127_4802500_1 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001687 206.0
CSH3_k127_4802500_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.00000000000000000000000000000000000000000000212 171.0
CSH3_k127_4802500_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000001001 124.0
CSH3_k127_4802500_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000001856 87.0
CSH3_k127_4802500_5 response regulator receiver K02657 - - 0.00000033 57.0
CSH3_k127_4920239_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 597.0
CSH3_k127_4920239_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 558.0
CSH3_k127_4920239_10 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002927 235.0
CSH3_k127_4920239_11 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000001874 232.0
CSH3_k127_4920239_12 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000004049 212.0
CSH3_k127_4920239_13 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000006285 218.0
CSH3_k127_4920239_14 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000001617 204.0
CSH3_k127_4920239_15 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000001381 198.0
CSH3_k127_4920239_16 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.000000000000000000000000000000000000000000000000008962 193.0
CSH3_k127_4920239_17 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000001724 176.0
CSH3_k127_4920239_18 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000008591 145.0
CSH3_k127_4920239_19 Predicted SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000002573 132.0
CSH3_k127_4920239_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 399.0
CSH3_k127_4920239_20 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000004225 133.0
CSH3_k127_4920239_21 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000006966 91.0
CSH3_k127_4920239_22 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000005157 58.0
CSH3_k127_4920239_23 Pectate lyase - - - 0.00003702 57.0
CSH3_k127_4920239_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 364.0
CSH3_k127_4920239_4 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 341.0
CSH3_k127_4920239_5 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
CSH3_k127_4920239_6 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 313.0
CSH3_k127_4920239_7 calcium proton exchanger K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001703 286.0
CSH3_k127_4920239_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002375 268.0
CSH3_k127_4920239_9 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000001259 239.0
CSH3_k127_4920376_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 510.0
CSH3_k127_4920376_1 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000002878 195.0
CSH3_k127_4920376_2 Papain family cysteine protease - - - 0.0000000000000000001689 101.0
CSH3_k127_4920376_3 Belongs to the peptidase S8 family - - - 0.0000000002519 71.0
CSH3_k127_4920376_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000007219 55.0
CSH3_k127_4943416_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 590.0
CSH3_k127_4943416_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 556.0
CSH3_k127_4943416_10 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000009327 205.0
CSH3_k127_4943416_11 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.0000000000000000000000000000000000000000000000000007662 190.0
CSH3_k127_4943416_12 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000001421 185.0
CSH3_k127_4943416_13 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000003886 180.0
CSH3_k127_4943416_14 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000009034 169.0
CSH3_k127_4943416_15 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000006631 139.0
CSH3_k127_4943416_16 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000008689 136.0
CSH3_k127_4943416_17 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000001414 128.0
CSH3_k127_4943416_18 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000003505 115.0
CSH3_k127_4943416_19 Integral membrane protein DUF106 - - - 0.000000000000000000000001837 111.0
CSH3_k127_4943416_2 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 534.0
CSH3_k127_4943416_20 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003391 103.0
CSH3_k127_4943416_21 - - - - 0.00000000000000004049 83.0
CSH3_k127_4943416_22 - - - - 0.000000000000008397 83.0
CSH3_k127_4943416_23 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000002491 70.0
CSH3_k127_4943416_24 - - - - 0.00000001293 69.0
CSH3_k127_4943416_25 N-terminal 7TM region of histidine kinase - - - 0.0000009415 57.0
CSH3_k127_4943416_26 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00009655 52.0
CSH3_k127_4943416_3 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 534.0
CSH3_k127_4943416_4 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 447.0
CSH3_k127_4943416_5 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 369.0
CSH3_k127_4943416_6 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 369.0
CSH3_k127_4943416_7 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 292.0
CSH3_k127_4943416_8 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002368 227.0
CSH3_k127_4943416_9 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
CSH3_k127_4998149_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 491.0
CSH3_k127_4998149_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 478.0
CSH3_k127_4998149_10 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000009612 115.0
CSH3_k127_4998149_11 Transcriptional regulator, TrmB - - - 0.0000000000000000000000002042 110.0
CSH3_k127_4998149_12 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000001907 101.0
CSH3_k127_4998149_13 - - - - 0.00000000003856 75.0
CSH3_k127_4998149_14 Domain of unknown function (DUF4314) - - - 0.00000002245 57.0
CSH3_k127_4998149_15 Lrp/AsnC ligand binding domain - - - 0.0000001632 53.0
CSH3_k127_4998149_2 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 481.0
CSH3_k127_4998149_3 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 394.0
CSH3_k127_4998149_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 353.0
CSH3_k127_4998149_5 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 331.0
CSH3_k127_4998149_6 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 318.0
CSH3_k127_4998149_7 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000011 235.0
CSH3_k127_4998149_8 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000000000000000000000000000000000126 205.0
CSH3_k127_4998149_9 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000002131 160.0
CSH3_k127_5010382_0 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.00000000000000000000000000000000000000000003814 177.0
CSH3_k127_5010382_1 metallopeptidase activity K01186 - 3.2.1.18 0.0000000000000000806 92.0
CSH3_k127_5010382_2 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000008005 90.0
CSH3_k127_5010382_3 toxin activity - - - 0.000000000001112 78.0
CSH3_k127_5010382_4 LVIVD repeat-containing protein - - - 0.000000000002956 79.0
CSH3_k127_503118_0 Protein of unknown function (DUF3887) K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 362.0
CSH3_k127_503118_1 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 367.0
CSH3_k127_503118_2 Belongs to the TPP enzyme family K00158 - 1.2.3.3 0.000000000000000000000000000000000000000000000000000000001152 203.0
CSH3_k127_5034961_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 597.0
CSH3_k127_5034961_1 Zn_pept - - - 0.000000000000000000000000005826 128.0
CSH3_k127_5034961_2 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000005296 87.0
CSH3_k127_5034961_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000006769 56.0
CSH3_k127_5238874_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
CSH3_k127_5238874_1 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000002347 214.0
CSH3_k127_5238874_2 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000008032 155.0
CSH3_k127_5378952_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1154.0
CSH3_k127_5378952_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 9.203e-260 833.0
CSH3_k127_5378952_10 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 335.0
CSH3_k127_5378952_11 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 298.0
CSH3_k127_5378952_12 GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 297.0
CSH3_k127_5378952_13 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006013 286.0
CSH3_k127_5378952_14 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006436 281.0
CSH3_k127_5378952_15 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000000000000000000068 253.0
CSH3_k127_5378952_16 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000006161 221.0
CSH3_k127_5378952_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000004424 209.0
CSH3_k127_5378952_18 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000001003 207.0
CSH3_k127_5378952_19 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000001463 203.0
CSH3_k127_5378952_2 FMN binding - - - 6.239e-244 763.0
CSH3_k127_5378952_20 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004643 193.0
CSH3_k127_5378952_21 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000001961 178.0
CSH3_k127_5378952_22 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000001325 130.0
CSH3_k127_5378952_23 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000004576 117.0
CSH3_k127_5378952_24 LVIVD repeat-containing protein - - - 0.000000000000000000000001811 123.0
CSH3_k127_5378952_25 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000004704 99.0
CSH3_k127_5378952_26 Belongs to the UPF0235 family K09131 - - 0.00000000000000000002618 94.0
CSH3_k127_5378952_27 TOPRIM - - - 0.000000000000000001251 91.0
CSH3_k127_5378952_28 Zn-ribbon containing protein K07163 - - 0.00000000000000003919 88.0
CSH3_k127_5378952_29 Methyltransferase domain - - - 0.00000000000003937 80.0
CSH3_k127_5378952_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 4.623e-219 686.0
CSH3_k127_5378952_30 - - - - 0.00000000001784 75.0
CSH3_k127_5378952_31 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000008679 68.0
CSH3_k127_5378952_32 PFAM GCN5-related N-acetyltransferase - - - 0.0000001732 60.0
CSH3_k127_5378952_33 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.00000026 66.0
CSH3_k127_5378952_34 AMP-binding enzyme C-terminal domain - - - 0.0000024 61.0
CSH3_k127_5378952_35 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000008986 57.0
CSH3_k127_5378952_36 Fibronectin type 3 domain - - - 0.00001592 60.0
CSH3_k127_5378952_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 618.0
CSH3_k127_5378952_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 604.0
CSH3_k127_5378952_6 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 475.0
CSH3_k127_5378952_7 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 468.0
CSH3_k127_5378952_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 370.0
CSH3_k127_5378952_9 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
CSH3_k127_5479029_0 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 327.0
CSH3_k127_5479029_1 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 315.0
CSH3_k127_5479029_2 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 291.0
CSH3_k127_5479029_3 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
CSH3_k127_5479029_4 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002931 254.0
CSH3_k127_5479029_5 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000007766 216.0
CSH3_k127_5479029_6 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000001425 198.0
CSH3_k127_5479029_7 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000005166 126.0
CSH3_k127_5479029_8 cluster protein-associated redox disulfide domain - - - 0.000000000000001868 78.0
CSH3_k127_5479029_9 Psort location Cytoplasmic, score 8.87 - - - 0.000002375 54.0
CSH3_k127_5580129_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 361.0
CSH3_k127_5580129_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 299.0
CSH3_k127_5580129_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000006339 267.0
CSH3_k127_5580129_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
CSH3_k127_5580129_4 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003926 248.0
CSH3_k127_5580129_5 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000000000000000000000000000000000000001242 213.0
CSH3_k127_5580129_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000006505 194.0
CSH3_k127_5580129_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000006742 182.0
CSH3_k127_5580129_8 Putative small multi-drug export protein - - - 0.000000000000000000000000000003179 125.0
CSH3_k127_5633327_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 373.0
CSH3_k127_5633327_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000001147 113.0
CSH3_k127_5633327_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000001093 80.0
CSH3_k127_5633327_3 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0004524 52.0
CSH3_k127_5813837_0 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 437.0
CSH3_k127_5813837_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
CSH3_k127_5813837_10 Metallopeptidase family M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000002139 134.0
CSH3_k127_5813837_11 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.0000000000000000000000000000000009238 135.0
CSH3_k127_5813837_12 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000001035 130.0
CSH3_k127_5813837_13 Protein of unknown function (DUF1349) - - - 0.000000000000000000000001702 121.0
CSH3_k127_5813837_14 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000006271 118.0
CSH3_k127_5813837_15 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000001569 78.0
CSH3_k127_5813837_16 Protein of unknown function (DUF998) - - - 0.0000000000001786 78.0
CSH3_k127_5813837_17 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000275 83.0
CSH3_k127_5813837_18 - - - - 0.000000000000411 72.0
CSH3_k127_5813837_19 peptidase activity, acting on L-amino acid peptides K01337,K13735,K20276 - 3.4.21.50 0.00000003297 68.0
CSH3_k127_5813837_2 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003342 250.0
CSH3_k127_5813837_20 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 0.00008397 56.0
CSH3_k127_5813837_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000001506 233.0
CSH3_k127_5813837_4 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
CSH3_k127_5813837_5 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000005441 237.0
CSH3_k127_5813837_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000005114 199.0
CSH3_k127_5813837_7 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000003637 166.0
CSH3_k127_5813837_8 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000001708 168.0
CSH3_k127_5813837_9 PFAM thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000004359 141.0
CSH3_k127_5891277_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1587.0
CSH3_k127_5891277_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.046e-217 700.0
CSH3_k127_5891277_10 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 367.0
CSH3_k127_5891277_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
CSH3_k127_5891277_12 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 355.0
CSH3_k127_5891277_13 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 295.0
CSH3_k127_5891277_14 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004377 278.0
CSH3_k127_5891277_15 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000002273 267.0
CSH3_k127_5891277_16 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002427 254.0
CSH3_k127_5891277_17 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
CSH3_k127_5891277_18 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001596 231.0
CSH3_k127_5891277_19 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000001835 231.0
CSH3_k127_5891277_2 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 5.764e-196 622.0
CSH3_k127_5891277_20 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000002396 211.0
CSH3_k127_5891277_21 - - - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
CSH3_k127_5891277_22 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000005895 191.0
CSH3_k127_5891277_23 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000001164 178.0
CSH3_k127_5891277_24 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.0000000000000000000000000000000000000000000001303 184.0
CSH3_k127_5891277_25 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000001699 166.0
CSH3_k127_5891277_26 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000003391 140.0
CSH3_k127_5891277_27 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000001153 118.0
CSH3_k127_5891277_28 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000001496 123.0
CSH3_k127_5891277_29 Hydrogenase maturation protease K03605 - - 0.000000000000000000000001267 108.0
CSH3_k127_5891277_3 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 574.0
CSH3_k127_5891277_30 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000003369 101.0
CSH3_k127_5891277_31 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000008817 109.0
CSH3_k127_5891277_32 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.00000000000000000004758 103.0
CSH3_k127_5891277_33 - - - - 0.000000000000000008698 93.0
CSH3_k127_5891277_34 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000017 80.0
CSH3_k127_5891277_35 PFAM SMP-30 Gluconolaconase - - - 0.000000000000001188 89.0
CSH3_k127_5891277_37 protein conserved in archaea K09723 - - 0.00000000007034 70.0
CSH3_k127_5891277_38 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000006154 58.0
CSH3_k127_5891277_39 PFAM BioY K03523 - - 0.0008175 45.0
CSH3_k127_5891277_4 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 567.0
CSH3_k127_5891277_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 469.0
CSH3_k127_5891277_6 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 419.0
CSH3_k127_5891277_7 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 406.0
CSH3_k127_5891277_8 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 381.0
CSH3_k127_5891277_9 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 366.0
CSH3_k127_5964882_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 488.0
CSH3_k127_5964882_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 406.0
CSH3_k127_5964882_10 bacterial-type flagellum-dependent cell motility - - - 0.00000000004671 76.0
CSH3_k127_5964882_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001989 271.0
CSH3_k127_5964882_3 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000163 238.0
CSH3_k127_5964882_4 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.000000000000000000000000000000000000000000000000000000000000000003359 241.0
CSH3_k127_5964882_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001758 226.0
CSH3_k127_5964882_6 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006468 218.0
CSH3_k127_5964882_7 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000000000008073 227.0
CSH3_k127_5964882_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000000000000000007594 121.0
CSH3_k127_5964882_9 secreted hydrolase - - - 0.00000000000000002098 94.0
CSH3_k127_5993092_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1120.0
CSH3_k127_5993092_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000002643 96.0
CSH3_k127_5993092_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000003004 65.0
CSH3_k127_6003107_0 Proprotein convertase P-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 570.0
CSH3_k127_6003107_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000005099 239.0
CSH3_k127_6003107_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000955 61.0
CSH3_k127_6004396_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 5.16e-314 991.0
CSH3_k127_6004396_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147,K22465 - 4.1.99.17,4.1.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 488.0
CSH3_k127_6004396_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 369.0
CSH3_k127_6004396_3 Zinc metalloprotease (Elastase) - - - 0.00000000000000002592 94.0
CSH3_k127_6070745_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1131.0
CSH3_k127_6070745_1 Cell division protein 48 (CDC48) domain 2 K13525 - - 9.095e-277 875.0
CSH3_k127_6070745_10 - - - - 0.00002442 53.0
CSH3_k127_6070745_2 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 462.0
CSH3_k127_6070745_3 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000001247 215.0
CSH3_k127_6070745_4 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000001809 220.0
CSH3_k127_6070745_5 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.00000000000000000000000000000000004244 137.0
CSH3_k127_6070745_6 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000002285 102.0
CSH3_k127_6070745_7 PRC-barrel domain - - - 0.000000000000001906 79.0
CSH3_k127_6070745_8 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000009223 78.0
CSH3_k127_6070745_9 - - - - 0.00000002577 61.0
CSH3_k127_6094840_0 PFAM CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 385.0
CSH3_k127_6094840_1 PFAM Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000005126 195.0
CSH3_k127_6094840_2 EamA-like transporter family - - - 0.0000000000000000000000000003083 118.0
CSH3_k127_6105415_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 480.0
CSH3_k127_6105415_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 454.0
CSH3_k127_6105415_10 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000009177 269.0
CSH3_k127_6105415_11 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006209 266.0
CSH3_k127_6105415_12 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000009043 207.0
CSH3_k127_6105415_13 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000007518 197.0
CSH3_k127_6105415_14 PFAM regulatory protein, ArsR - - - 0.0000000000000000002645 96.0
CSH3_k127_6105415_15 Domain of unknown function (DUF1610) K07580 - - 0.000000000000002689 76.0
CSH3_k127_6105415_16 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000003038 72.0
CSH3_k127_6105415_2 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 424.0
CSH3_k127_6105415_3 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 368.0
CSH3_k127_6105415_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 335.0
CSH3_k127_6105415_5 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 315.0
CSH3_k127_6105415_6 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 317.0
CSH3_k127_6105415_7 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 303.0
CSH3_k127_6105415_8 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 301.0
CSH3_k127_6105415_9 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000113 273.0
CSH3_k127_6129253_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.948e-237 741.0
CSH3_k127_6129253_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 568.0
CSH3_k127_6129253_10 COG3420 Nitrous oxidase accessory protein K07218 - - 0.000000000000001051 89.0
CSH3_k127_6129253_11 cell wall organization - - - 0.000000000000115 84.0
CSH3_k127_6129253_12 cell wall organization - - - 0.0000000000003198 82.0
CSH3_k127_6129253_13 peptidase activity, acting on L-amino acid peptides - - - 0.0002202 54.0
CSH3_k127_6129253_2 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 428.0
CSH3_k127_6129253_3 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000001037 187.0
CSH3_k127_6129253_4 PFAM elongation factor Tu, domain 2 protein - - - 0.00000000000000000000000000000000000000000000000009868 189.0
CSH3_k127_6129253_5 FMN binding - - - 0.0000000000000000000000000000000000000000003023 163.0
CSH3_k127_6129253_6 TraB family - - - 0.000000000000000000000000000000000004841 146.0
CSH3_k127_6129253_7 KaiC K08482 - - 0.0000000000000000000000005992 115.0
CSH3_k127_6129253_8 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000007282 113.0
CSH3_k127_6129253_9 Belongs to the peptidase S8 family K20276 - - 0.0000000000000000005176 103.0
CSH3_k127_6164316_0 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 607.0
CSH3_k127_6164316_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 499.0
CSH3_k127_6164316_10 nitrogen compound transport K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 378.0
CSH3_k127_6164316_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 369.0
CSH3_k127_6164316_12 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 337.0
CSH3_k127_6164316_13 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 335.0
CSH3_k127_6164316_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 239.0
CSH3_k127_6164316_15 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000305 236.0
CSH3_k127_6164316_16 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001016 235.0
CSH3_k127_6164316_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000001142 186.0
CSH3_k127_6164316_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000002589 182.0
CSH3_k127_6164316_19 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005885 168.0
CSH3_k127_6164316_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 478.0
CSH3_k127_6164316_20 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000001801 185.0
CSH3_k127_6164316_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000004115 160.0
CSH3_k127_6164316_22 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002405 146.0
CSH3_k127_6164316_23 Pfam:DUF552 K09152 - - 0.0000000000000000000000001039 110.0
CSH3_k127_6164316_24 PFAM Activator of Hsp90 ATPase - - - 0.000000000000000000000002956 106.0
CSH3_k127_6164316_25 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000001212 100.0
CSH3_k127_6164316_26 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000001276 104.0
CSH3_k127_6164316_27 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000001501 89.0
CSH3_k127_6164316_28 - - - - 0.000000000000002151 83.0
CSH3_k127_6164316_29 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002142 74.0
CSH3_k127_6164316_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 472.0
CSH3_k127_6164316_30 PFAM Peptidase C1A, papain - - - 0.0000000000001608 81.0
CSH3_k127_6164316_31 PFAM NHL repeat containing protein - - - 0.00000000006132 72.0
CSH3_k127_6164316_32 PFAM PKD domain containing protein - - - 0.0000000006204 73.0
CSH3_k127_6164316_33 PKD domain - - - 0.000000003251 69.0
CSH3_k127_6164316_34 Uncharacterised protein family (UPF0227) K07000 - - 0.0000002958 60.0
CSH3_k127_6164316_35 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000002959 59.0
CSH3_k127_6164316_36 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0001565 52.0
CSH3_k127_6164316_4 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 428.0
CSH3_k127_6164316_5 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 413.0
CSH3_k127_6164316_6 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 413.0
CSH3_k127_6164316_7 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 407.0
CSH3_k127_6164316_8 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 398.0
CSH3_k127_6164316_9 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 381.0
CSH3_k127_6218804_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 598.0
CSH3_k127_6218804_1 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 488.0
CSH3_k127_6218804_10 Caspase domain - - - 0.000001136 59.0
CSH3_k127_6218804_11 metallopeptidase activity - - - 0.0000695 46.0
CSH3_k127_6218804_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 465.0
CSH3_k127_6218804_3 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 432.0
CSH3_k127_6218804_4 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
CSH3_k127_6218804_5 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001484 268.0
CSH3_k127_6218804_6 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000112 217.0
CSH3_k127_6218804_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000007161 171.0
CSH3_k127_6218804_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000007812 164.0
CSH3_k127_6218804_9 Vacuolar protein sorting-associated protein 62 - GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006605,GO:0006623,GO:0006810,GO:0006886,GO:0007034,GO:0008104,GO:0008150,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0031090,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072665,GO:0072666,GO:0098588,GO:0098805,GO:0098852 - 0.0000000000000006889 91.0
CSH3_k127_6308399_0 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 2.639e-241 760.0
CSH3_k127_6308399_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 605.0
CSH3_k127_6308399_10 PFAM Nitroreductase - - - 0.000000000000002603 89.0
CSH3_k127_6308399_11 Micrococcal nuclease (thermonuclease) homologs K01174,K02238 - 3.1.31.1 0.00000003231 67.0
CSH3_k127_6308399_12 APHP domain protein - - - 0.0000009809 60.0
CSH3_k127_6308399_2 deoxyribonuclease I activity K06131,K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 345.0
CSH3_k127_6308399_3 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000001001 211.0
CSH3_k127_6308399_4 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000001999 191.0
CSH3_k127_6308399_5 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000002254 190.0
CSH3_k127_6308399_6 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000002842 168.0
CSH3_k127_6308399_7 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000000393 123.0
CSH3_k127_6308399_8 Rhomboid family - - - 0.000000000000000000000003046 114.0
CSH3_k127_6308399_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000001775 92.0
CSH3_k127_6391062_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.647e-273 861.0
CSH3_k127_6391062_1 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 502.0
CSH3_k127_6391062_2 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000002721 191.0
CSH3_k127_6391062_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000001027 167.0
CSH3_k127_6391062_4 4 iron, 4 sulfur cluster binding K00196 - - 0.000000000000000000000000000000001734 134.0
CSH3_k127_6391062_5 GPR1 FUN34 yaaH family protein K07034 - - 0.000000000000000000000000003452 119.0
CSH3_k127_6391062_6 Belongs to the UPF0178 family - - - 0.0000000000000000000000005744 106.0
CSH3_k127_6407384_0 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 298.0
CSH3_k127_6407384_1 Chitin synthase K00752 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605,GO:0090609 2.4.1.212 0.0000000000000000000000000000000000000000000000000000000000000001785 227.0
CSH3_k127_6407384_2 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000733 165.0
CSH3_k127_6407384_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000006647 142.0
CSH3_k127_6407384_4 PFAM Peptidase C1A, papain - - - 0.000000000000000000000003077 120.0
CSH3_k127_6421851_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 2.476e-242 762.0
CSH3_k127_6421851_1 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 317.0
CSH3_k127_6421851_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005282 271.0
CSH3_k127_6421851_3 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000009574 200.0
CSH3_k127_6421851_4 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000002811 198.0
CSH3_k127_6421851_5 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.000000007407 57.0
CSH3_k127_6513725_0 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 392.0
CSH3_k127_6513725_1 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 402.0
CSH3_k127_6513725_10 chitinase K01183 - 3.2.1.14 0.00000000000001837 87.0
CSH3_k127_6513725_11 PKD domain - - - 0.0000000000001763 85.0
CSH3_k127_6513725_12 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.000005684 57.0
CSH3_k127_6513725_13 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00004176 56.0
CSH3_k127_6513725_2 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 329.0
CSH3_k127_6513725_3 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 307.0
CSH3_k127_6513725_4 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000002572 237.0
CSH3_k127_6513725_5 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000001021 177.0
CSH3_k127_6513725_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001117 156.0
CSH3_k127_6513725_7 Acetyltransferase (GNAT) domain K03823 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 0.00000000000000000000000000000000003453 140.0
CSH3_k127_6513725_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000001695 147.0
CSH3_k127_6513725_9 - - - - 0.0000000000000000000000001716 112.0
CSH3_k127_6544737_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.768e-195 627.0
CSH3_k127_6544737_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 499.0
CSH3_k127_6544737_2 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 334.0
CSH3_k127_6544737_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000006134 173.0
CSH3_k127_6544737_4 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000002676 168.0
CSH3_k127_6544737_5 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000001124 123.0
CSH3_k127_6544737_6 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000003554 69.0
CSH3_k127_6544737_7 Copper binding proteins, plastocyanin/azurin family - - - 0.000000007373 68.0
CSH3_k127_6544737_8 cell wall organization - - - 0.0000001133 63.0
CSH3_k127_6606141_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 1.784e-268 850.0
CSH3_k127_6606141_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 360.0
CSH3_k127_6606141_11 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000003796 218.0
CSH3_k127_6606141_12 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000006347 203.0
CSH3_k127_6606141_13 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000004565 178.0
CSH3_k127_6606141_14 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000002741 164.0
CSH3_k127_6606141_15 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07005 - - 0.00000000000000000000000000000000000000008779 156.0
CSH3_k127_6606141_16 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000002478 163.0
CSH3_k127_6606141_17 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000004021 135.0
CSH3_k127_6606141_18 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000002655 130.0
CSH3_k127_6606141_19 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000001446 122.0
CSH3_k127_6606141_2 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 360.0
CSH3_k127_6606141_20 amino acid activation for nonribosomal peptide biosynthetic process K20276 - - 0.0000000000000000000000002281 123.0
CSH3_k127_6606141_21 phosphorelay signal transduction system K07658 - - 0.00000000000000000000005398 102.0
CSH3_k127_6606141_22 YHS domain - - - 0.000000000000000000001606 93.0
CSH3_k127_6606141_23 Peptidase_C39 like family - - - 0.000000000000000000003819 100.0
CSH3_k127_6606141_24 Major facilitator Superfamily K08162,K08226,K16211 - - 0.00000000000003853 84.0
CSH3_k127_6606141_25 Sterol carrier protein - - - 0.000000000005943 71.0
CSH3_k127_6606141_26 Periplasmic copper-binding protein (NosD) - - - 0.0000000002375 72.0
CSH3_k127_6606141_27 signal transduction protein with CBS domains - - - 0.0000000005158 71.0
CSH3_k127_6606141_28 Beta-galactosidase - - - 0.0000000005389 73.0
CSH3_k127_6606141_29 membrane-associated protein domain - - - 0.000000001563 70.0
CSH3_k127_6606141_3 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 346.0
CSH3_k127_6606141_30 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000002439 60.0
CSH3_k127_6606141_31 Bacterial Ig-like domain (group 3) - - - 0.0000001356 64.0
CSH3_k127_6606141_32 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.0000008643 60.0
CSH3_k127_6606141_33 lycopene cyclase - - - 0.00000214 54.0
CSH3_k127_6606141_34 membrane-associated protein domain - - - 0.000006734 59.0
CSH3_k127_6606141_35 COG1522 Transcriptional regulators - - - 0.00001129 57.0
CSH3_k127_6606141_36 Bacterial PH domain - - - 0.0004605 52.0
CSH3_k127_6606141_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 340.0
CSH3_k127_6606141_5 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 306.0
CSH3_k127_6606141_6 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
CSH3_k127_6606141_7 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001007 254.0
CSH3_k127_6606141_8 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006597 243.0
CSH3_k127_6606141_9 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000001934 240.0
CSH3_k127_6728581_0 Heat shock 70 kDa protein K04043 - - 2.227e-241 760.0
CSH3_k127_6728581_1 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 6.227e-234 738.0
CSH3_k127_6728581_10 pathogenesis K13669 - - 0.00000000004034 77.0
CSH3_k127_6728581_11 Bacterial pre-peptidase C-terminal domain K01337,K05994 - 3.4.11.10,3.4.21.50 0.000001312 55.0
CSH3_k127_6728581_12 GDSL-like Lipase/Acylhydrolase family K06882 - - 0.00005138 57.0
CSH3_k127_6728581_2 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 8.428e-220 695.0
CSH3_k127_6728581_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 439.0
CSH3_k127_6728581_4 Chlorophyllase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000002981 230.0
CSH3_k127_6728581_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000009907 190.0
CSH3_k127_6728581_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000005958 95.0
CSH3_k127_6728581_7 Universal stress protein family - - - 0.00000000000001501 79.0
CSH3_k127_6728581_8 Domain of unknown function (DUF2341) - - - 0.000000000004443 80.0
CSH3_k127_6728581_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000006376 71.0
CSH3_k127_6814033_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000727 248.0
CSH3_k127_6814033_1 calcium- and calmodulin-responsive adenylate cyclase activity K13735,K20276,K21449 - - 0.0000000000000000000000000000000000000000000000000000000002614 218.0
CSH3_k127_6814033_2 PFAM Forkhead-associated protein - - - 0.000000000000000000000007417 114.0
CSH3_k127_6814033_3 COG1520 FOG WD40-like repeat - - - 0.00003397 55.0
CSH3_k127_6854088_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 363.0
CSH3_k127_6854088_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000003396 227.0
CSH3_k127_6854088_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000001569 87.0
CSH3_k127_6854088_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001429 67.0
CSH3_k127_6873753_0 aconitate hydratase K01681 - 4.2.1.3 6.904e-285 888.0
CSH3_k127_6873753_1 TIGRFAM Acetate-CoA ligase K01895 - 6.2.1.1 2.868e-274 857.0
CSH3_k127_6873753_2 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 315.0
CSH3_k127_6873753_3 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000353 204.0
CSH3_k127_6873753_4 COG1522 Transcriptional regulators - - - 0.000000000000000000000006126 114.0
CSH3_k127_6888101_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 456.0
CSH3_k127_6888101_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 367.0
CSH3_k127_6888101_2 Right handed beta helix region - - - 0.0000000003592 71.0
CSH3_k127_6888101_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000003247 68.0
CSH3_k127_860274_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 3.571e-303 952.0
CSH3_k127_860274_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 3.493e-260 812.0
CSH3_k127_860274_10 parallel beta-helix repeat K03671 - - 0.000000000000002952 87.0
CSH3_k127_860274_11 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 0.00000000000002333 81.0
CSH3_k127_860274_12 Peptidase family C25 - - - 0.000002768 60.0
CSH3_k127_860274_2 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 4.973e-256 797.0
CSH3_k127_860274_3 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 535.0
CSH3_k127_860274_4 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 457.0
CSH3_k127_860274_5 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 435.0
CSH3_k127_860274_6 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 302.0
CSH3_k127_860274_7 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000003067 246.0
CSH3_k127_860274_8 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000004449 196.0
CSH3_k127_860274_9 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000001596 195.0