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Overview

ID MAG00636
Name CSH3_bin.36
Sample SMP0015
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanosarcinia
Order Methanosarcinales
Family Methanoperedenaceae
Genus Methanoperedens
Species
Assembly information
Completeness (%) 94.7
Contamination (%) 1.7
GC content (%) 40.0
N50 (bp) 16,715
Genome size (bp) 2,744,061

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2544

Gene name Description KEGG GOs EC E-value Score Sequence
CSH3_k127_1006353_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 457.0
CSH3_k127_1006353_1 Putative zinc- or iron-chelating domain - - - 0.000000000000007388 81.0
CSH3_k127_1006353_2 Putative zinc- or iron-chelating domain - - - 0.00000000002398 64.0
CSH3_k127_1026776_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 486.0
CSH3_k127_1026776_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 452.0
CSH3_k127_1026776_10 - - - - 0.00000000000000000000000000000008672 129.0
CSH3_k127_1026776_11 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000008426 103.0
CSH3_k127_1026776_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 - - - 0.00000000000000000001616 97.0
CSH3_k127_1026776_13 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000001279 87.0
CSH3_k127_1026776_14 Universal stress protein family - - - 0.0000000000000001057 85.0
CSH3_k127_1026776_15 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000001115 84.0
CSH3_k127_1026776_16 ABC transporter K01990 - - 0.0000000000000004892 80.0
CSH3_k127_1026776_18 Adenylate guanylate cyclase K01768 - 4.6.1.1 0.0000106 57.0
CSH3_k127_1026776_19 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0001349 53.0
CSH3_k127_1026776_2 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 366.0
CSH3_k127_1026776_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003264 273.0
CSH3_k127_1026776_4 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004368 258.0
CSH3_k127_1026776_5 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000007209 220.0
CSH3_k127_1026776_6 SMART HEPN domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002415 214.0
CSH3_k127_1026776_7 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000002987 181.0
CSH3_k127_1026776_8 Yip1 domain - - - 0.0000000000000000000000000000000000001198 147.0
CSH3_k127_1026776_9 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000000000002444 141.0
CSH3_k127_106638_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 340.0
CSH3_k127_106638_1 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000117 194.0
CSH3_k127_106638_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000001023 111.0
CSH3_k127_106638_3 Transposase zinc-binding domain - - - 0.00000000000000000000006526 102.0
CSH3_k127_106638_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000002213 81.0
CSH3_k127_106638_5 Protein of unknown function (DUF2769) - - - 0.0000000000001845 74.0
CSH3_k127_1088112_0 PFAM Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000006987 221.0
CSH3_k127_1088112_1 Transposase - - - 0.0000000000000000000000000000000000000000000003439 183.0
CSH3_k127_1146805_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.496e-200 631.0
CSH3_k127_1146805_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 319.0
CSH3_k127_1146805_10 Cobalt transport protein component CbiN K02009 - - 0.000000000000000000004349 95.0
CSH3_k127_1146805_11 to orf3 of fosmid clone 4B7mr3 - - - 0.0000000000000000007028 94.0
CSH3_k127_1146805_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000000002258 71.0
CSH3_k127_1146805_13 COG3316 Transposase and inactivated derivatives K07498 - - 0.00000004992 58.0
CSH3_k127_1146805_2 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005911 269.0
CSH3_k127_1146805_3 Histidine carboxylase PI chain K01590 - 4.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000227 239.0
CSH3_k127_1146805_4 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000008313 227.0
CSH3_k127_1146805_5 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000004459 199.0
CSH3_k127_1146805_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000144 198.0
CSH3_k127_1146805_7 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000004651 189.0
CSH3_k127_1146805_8 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000003359 124.0
CSH3_k127_1146805_9 to orf3 of fosmid clone 4B7mr3 - - - 0.0000000000000000000007158 104.0
CSH3_k127_1175125_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 384.0
CSH3_k127_1175125_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001806 283.0
CSH3_k127_1175125_2 Plasmid pRiA4b ORF-3-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005653 239.0
CSH3_k127_1175125_5 COG3316 Transposase and inactivated derivatives - - - 0.00001929 46.0
CSH3_k127_1181227_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 7.644e-197 623.0
CSH3_k127_1181227_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 603.0
CSH3_k127_1181227_10 DGC domain - - - 0.00000000000000000000001899 102.0
CSH3_k127_1181227_11 - - - - 0.00000000000000001823 88.0
CSH3_k127_1181227_12 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000005129 80.0
CSH3_k127_1181227_13 Cupin 2 conserved barrel domain - - - 0.000000000000003281 76.0
CSH3_k127_1181227_14 - - - - 0.00000000000001597 79.0
CSH3_k127_1181227_15 Bacterial regulatory protein, arsR family - - - 0.0000000000001338 74.0
CSH3_k127_1181227_16 - - - - 0.00000000005694 68.0
CSH3_k127_1181227_17 Winged helix-turn-helix DNA-binding - - - 0.00005058 54.0
CSH3_k127_1181227_2 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 546.0
CSH3_k127_1181227_3 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000004712 241.0
CSH3_k127_1181227_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000002165 231.0
CSH3_k127_1181227_5 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000007483 149.0
CSH3_k127_1181227_6 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000003482 146.0
CSH3_k127_1181227_7 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000004264 138.0
CSH3_k127_1181227_8 4 iron, 4 sulfur cluster binding K00176,K00523 - 1.17.1.1,1.2.7.3 0.00000000000000000000000000000001177 132.0
CSH3_k127_1181227_9 Putative Fe-S cluster - - - 0.0000000000000000000000133 102.0
CSH3_k127_11845_0 Lysin motif K08307 - - 8.55e-197 633.0
CSH3_k127_11845_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 467.0
CSH3_k127_11845_2 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 433.0
CSH3_k127_11845_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 385.0
CSH3_k127_11845_4 Uncharacterized protein family UPF0054 K07042 - - 0.00000000000000000000004634 105.0
CSH3_k127_1203519_0 PFAM AIR synthase related protein K07388 - - 3.302e-200 632.0
CSH3_k127_1203519_1 PFAM Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 516.0
CSH3_k127_1203519_2 Single cache domain 3 K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 417.0
CSH3_k127_1203519_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000004621 233.0
CSH3_k127_1203519_4 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000001192 176.0
CSH3_k127_1203519_5 Belongs to the acylphosphatase family - - - 0.000000000000000000000000000000001162 137.0
CSH3_k127_1203519_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000000004556 130.0
CSH3_k127_1203519_7 periplasmic or secreted lipoprotein - - - 0.0000000000000000000005424 98.0
CSH3_k127_1203519_8 - - - - 0.0000000000007908 73.0
CSH3_k127_1207556_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1241.0
CSH3_k127_1207556_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.571e-212 673.0
CSH3_k127_1207556_10 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001431 272.0
CSH3_k127_1207556_11 COGs COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995,K11957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 250.0
CSH3_k127_1207556_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000515 248.0
CSH3_k127_1207556_13 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008994 243.0
CSH3_k127_1207556_14 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000001789 237.0
CSH3_k127_1207556_15 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.000000000000000000000000000000000000000000000000000000000000001914 224.0
CSH3_k127_1207556_16 ZPR1-related zinc finger protein K06874 - - 0.00000000000000000000000000000000000000000000000000000000000424 213.0
CSH3_k127_1207556_17 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000007105 205.0
CSH3_k127_1207556_18 PFAM PUA domain containing protein K07575 - - 0.00000000000000000000000000000000000000000000001669 175.0
CSH3_k127_1207556_19 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000001519 166.0
CSH3_k127_1207556_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.672e-212 666.0
CSH3_k127_1207556_20 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000005035 167.0
CSH3_k127_1207556_21 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000000002264 159.0
CSH3_k127_1207556_22 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000000000000000000000001003 153.0
CSH3_k127_1207556_23 Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000003249 146.0
CSH3_k127_1207556_24 Pfam:DUF552 K09152 - - 0.000000000000000000000000000000000005087 140.0
CSH3_k127_1207556_25 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000004481 133.0
CSH3_k127_1207556_26 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000003684 115.0
CSH3_k127_1207556_27 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000000000001151 113.0
CSH3_k127_1207556_28 binds to the 23S rRNA K02922 - - 0.000000000000000000002695 93.0
CSH3_k127_1207556_29 - - - - 0.0000000000000004177 84.0
CSH3_k127_1207556_3 S-layer protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 615.0
CSH3_k127_1207556_30 Rhs family - - - 0.0000000006017 73.0
CSH3_k127_1207556_4 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 531.0
CSH3_k127_1207556_5 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 395.0
CSH3_k127_1207556_6 PFAM GTP-binding protein HSR1-related K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 329.0
CSH3_k127_1207556_7 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 305.0
CSH3_k127_1207556_8 COG3547 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 311.0
CSH3_k127_1207556_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006516 278.0
CSH3_k127_1254493_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 452.0
CSH3_k127_1254493_1 Cys/Met metabolism PLP-dependent enzyme K01758,K01761 - 4.4.1.1,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 395.0
CSH3_k127_1254493_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000002257 129.0
CSH3_k127_1254493_3 DDE superfamily endonuclease - - - 0.0000000000000000000000001746 107.0
CSH3_k127_1258504_0 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 501.0
CSH3_k127_1258504_1 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 434.0
CSH3_k127_1258504_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 335.0
CSH3_k127_1258504_3 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000002505 120.0
CSH3_k127_1258504_4 - - - - 0.0000000000000000000000001098 112.0
CSH3_k127_1258504_5 type II restriction enzyme, methylase - - - 0.0000000000000000002202 104.0
CSH3_k127_1258504_6 SEFIR domain - - - 0.0008156 53.0
CSH3_k127_1258687_0 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 291.0
CSH3_k127_1258687_1 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003358 277.0
CSH3_k127_1258687_10 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.0000000001321 76.0
CSH3_k127_1258687_11 DNA ligase K01971 - 6.5.1.1 0.0000000005368 70.0
CSH3_k127_1258687_12 SIR2-like domain - - - 0.00000001644 64.0
CSH3_k127_1258687_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006188 278.0
CSH3_k127_1258687_3 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004215 256.0
CSH3_k127_1258687_4 - - - - 0.000000000000000000000000000000000000000000000005694 182.0
CSH3_k127_1258687_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000007935 166.0
CSH3_k127_1258687_6 - - - - 0.000000000000000000000000000000000001231 143.0
CSH3_k127_1258687_7 NAD+ binding - - - 0.0000000000000000000000000000004219 143.0
CSH3_k127_1258687_8 DDE superfamily endonuclease - - - 0.0000000000000000000004974 95.0
CSH3_k127_1258687_9 Cupin domain - - - 0.00000000000000266 79.0
CSH3_k127_1279552_0 Type III K01153 - 3.1.21.3 2.728e-287 897.0
CSH3_k127_1279552_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 302.0
CSH3_k127_1279552_2 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 297.0
CSH3_k127_1279552_3 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000009198 220.0
CSH3_k127_1279552_4 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000002749 167.0
CSH3_k127_1279552_5 Pfam:Gp37_Gp68 - - - 0.000000000000000000000000000000000000000004051 163.0
CSH3_k127_1279552_6 - - - - 0.00000000000000000000000000000000000002911 145.0
CSH3_k127_1279552_7 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000000000000000000000001098 143.0
CSH3_k127_1279552_8 Protein of unknown function (DUF433) - - - 0.0000000000000000001012 90.0
CSH3_k127_1279552_9 nucleic acid-binding protein contains PIN domain - - - 0.000000000000003133 81.0
CSH3_k127_1285161_0 TIGRFAM CRISPR-associated helicase Cas3 K07012 - - 2.028e-203 656.0
CSH3_k127_1285161_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 615.0
CSH3_k127_1285161_10 Radical SAM domain protein K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000001736 233.0
CSH3_k127_1285161_11 acetyl coenzyme A synthetase K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000005283 202.0
CSH3_k127_1285161_12 CRISPR-associated protein (Cas_Cas5) K19090 - - 0.0000000000000000000000000000000000000000000000000007512 192.0
CSH3_k127_1285161_13 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.0000000000000000000000000000000000000000000001014 172.0
CSH3_k127_1285161_14 Nucleotidyltransferase domain K07076 - - 0.000000000000000000000000000000000002182 142.0
CSH3_k127_1285161_15 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000001806 141.0
CSH3_k127_1285161_16 - - - - 0.00000000000000006606 94.0
CSH3_k127_1285161_17 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.0000000000000000972 81.0
CSH3_k127_1285161_18 Protein of unknown function DUF86 - - - 0.000000000002147 69.0
CSH3_k127_1285161_2 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 465.0
CSH3_k127_1285161_3 Beta-Casp domain K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 455.0
CSH3_k127_1285161_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 461.0
CSH3_k127_1285161_5 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 416.0
CSH3_k127_1285161_6 CRISPR-associated regulatory protein, DevR family K19075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 368.0
CSH3_k127_1285161_7 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 344.0
CSH3_k127_1285161_8 Methanogenesis marker protein 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 339.0
CSH3_k127_1285161_9 Family of unknown function (DUF5328) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 320.0
CSH3_k127_1285292_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 411.0
CSH3_k127_1285292_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000369 162.0
CSH3_k127_1285292_2 DDE superfamily endonuclease - - - 0.00000000008108 62.0
CSH3_k127_1303487_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.964e-256 800.0
CSH3_k127_1303487_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 3.389e-253 792.0
CSH3_k127_1303487_10 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000000000000000000000000000000000000001066 168.0
CSH3_k127_1303487_11 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000000000000000000002746 115.0
CSH3_k127_1303487_12 glycosyl transferase family 2 - - - 0.00000000000000000000000005751 117.0
CSH3_k127_1303487_13 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000000000001323 100.0
CSH3_k127_1303487_14 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000000000324 94.0
CSH3_k127_1303487_15 - - - - 0.000000000000000004787 89.0
CSH3_k127_1303487_16 TPR Domain containing protein - - - 0.00000000000134 81.0
CSH3_k127_1303487_17 AAA domain K07133 - - 0.00000000125 60.0
CSH3_k127_1303487_18 COG3335 Transposase and inactivated derivatives - - - 0.00000001416 62.0
CSH3_k127_1303487_19 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00001142 55.0
CSH3_k127_1303487_2 Type III restriction enzyme res subunit K10843 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 613.0
CSH3_k127_1303487_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 484.0
CSH3_k127_1303487_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 475.0
CSH3_k127_1303487_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 424.0
CSH3_k127_1303487_6 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 349.0
CSH3_k127_1303487_7 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 316.0
CSH3_k127_1303487_8 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
CSH3_k127_1303487_9 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000006781 254.0
CSH3_k127_1303488_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1476.0
CSH3_k127_1303488_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 458.0
CSH3_k127_1303488_2 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 337.0
CSH3_k127_1303488_3 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001039 278.0
CSH3_k127_1303488_4 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000002599 210.0
CSH3_k127_1303488_5 DsrE/DsrF-like family K07235 - - 0.000000000000000009307 87.0
CSH3_k127_1303488_6 protein involved in the oxidation of intracellular sulfur K07236 - - 0.0001089 49.0
CSH3_k127_1303488_7 DsrE/DsrF-like family - - - 0.0001267 49.0
CSH3_k127_1303488_8 Psort location Cytoplasmic, score 8.87 - - - 0.0002207 45.0
CSH3_k127_136233_0 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000008382 118.0
CSH3_k127_136233_1 - - - - 0.0000000000000001699 81.0
CSH3_k127_143040_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 415.0
CSH3_k127_143040_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 387.0
CSH3_k127_143040_2 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.000000004646 61.0
CSH3_k127_14386_0 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 355.0
CSH3_k127_14386_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 338.0
CSH3_k127_14386_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 284.0
CSH3_k127_14386_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000007798 177.0
CSH3_k127_14386_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000001627 166.0
CSH3_k127_14386_5 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001438 141.0
CSH3_k127_14386_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000002606 96.0
CSH3_k127_14386_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000006613 84.0
CSH3_k127_1438918_0 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000002992 203.0
CSH3_k127_1438918_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000002261 158.0
CSH3_k127_1438918_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000003728 156.0
CSH3_k127_1438918_3 - - - - 0.0000000000000000002189 100.0
CSH3_k127_1438918_4 Protein of unknown function (DUF3485) - - - 0.000000006974 66.0
CSH3_k127_1514532_0 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 445.0
CSH3_k127_1514532_1 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K07012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 305.0
CSH3_k127_1514532_2 CRISPR-associated protein Csc2 K19121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007979 286.0
CSH3_k127_1514532_3 - K19122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005793 296.0
CSH3_k127_1514532_4 PD-(D/E)XK nuclease superfamily K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000001312 211.0
CSH3_k127_1514532_5 AAA domain - - - 0.00000000000000000000000000000000000000000000005875 188.0
CSH3_k127_1514532_6 - K19120 - - 0.000000000000000000000000000000000000000002024 165.0
CSH3_k127_1514532_7 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.000000000000000000000000009148 111.0
CSH3_k127_1514532_8 - K19122 - - 0.000000000000000000002604 98.0
CSH3_k127_1514532_9 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000664 67.0
CSH3_k127_151541_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1084.0
CSH3_k127_151541_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 362.0
CSH3_k127_151541_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004281 257.0
CSH3_k127_151541_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000006917 187.0
CSH3_k127_151541_4 IS1 transposase - - - 0.00000000000000000000000000000000000000000000834 171.0
CSH3_k127_151541_6 protein conserved in archaea - - - 0.00000007383 58.0
CSH3_k127_1519536_0 Belongs to the glutamate synthase family - - - 4.431e-236 739.0
CSH3_k127_1519536_1 Radical SAM ThiC family K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 526.0
CSH3_k127_1519536_10 - - - - 0.000000000000000000000000000000000000000000000000000006651 193.0
CSH3_k127_1519536_11 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000122 167.0
CSH3_k127_1519536_12 Transcriptional regulator, TrmB - - - 0.000000000000000000000000121 110.0
CSH3_k127_1519536_13 4Fe-4S binding domain - - - 0.0000000000002196 71.0
CSH3_k127_1519536_2 PFAM glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 522.0
CSH3_k127_1519536_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 512.0
CSH3_k127_1519536_4 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 453.0
CSH3_k127_1519536_5 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 366.0
CSH3_k127_1519536_6 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 364.0
CSH3_k127_1519536_7 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 317.0
CSH3_k127_1519536_8 PFAM glutamate synthase alpha subunit domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
CSH3_k127_1519536_9 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000001448 201.0
CSH3_k127_1525059_0 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.0 1328.0
CSH3_k127_1525059_1 Product type e enzyme K03427 - 2.1.1.72 2.709e-272 842.0
CSH3_k127_1525059_2 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 368.0
CSH3_k127_1525059_3 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 313.0
CSH3_k127_1525059_4 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000008726 144.0
CSH3_k127_1525059_5 DNA polymerase beta domain protein region K07075 - - 0.000000000000000000000000000006302 121.0
CSH3_k127_1525059_6 PFAM DNA polymerase, beta domain protein region K07076 - - 0.000000000006823 71.0
CSH3_k127_1525059_7 Protein of unknown function DUF86 - - - 0.000001183 53.0
CSH3_k127_1574777_0 phage tail tape measure protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 453.0
CSH3_k127_1574777_1 ATPase, AAA superfamily K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 394.0
CSH3_k127_1574777_10 Chaperone of endosialidase - - - 0.000000003255 70.0
CSH3_k127_1574777_12 serine threonine protein kinase - - - 0.0007178 45.0
CSH3_k127_1574777_2 - - - - 0.0000000000000000000000000000000000005322 160.0
CSH3_k127_1574777_3 Baseplate J-like protein - - - 0.000000000000000000000000000000006428 140.0
CSH3_k127_1574777_4 Phage tail protein (Tail_P2_I) - - - 0.0000000000000000000000000001344 125.0
CSH3_k127_1574777_5 Baseplate J-like protein - - - 0.0000000000000000000000004689 114.0
CSH3_k127_1574777_6 Chaperone of endosialidase - - - 0.00000000000000000000018 111.0
CSH3_k127_1574777_7 serine threonine protein kinase - - - 0.000000000000000000000282 98.0
CSH3_k127_1574777_8 Protein of unknown function (DUF433) - - - 0.000000000000003698 77.0
CSH3_k127_1574777_9 Domain of unknown function (DUF4157) - - - 0.000000000000829 82.0
CSH3_k127_1574919_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 501.0
CSH3_k127_1574919_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 301.0
CSH3_k127_1574919_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000002081 177.0
CSH3_k127_1574919_11 PFAM Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000001859 174.0
CSH3_k127_1574919_12 Mo-molybdopterin cofactor metabolic process - - - 0.0000005713 53.0
CSH3_k127_1574919_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 295.0
CSH3_k127_1574919_3 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002378 243.0
CSH3_k127_1574919_4 SMART regulatory protein AsnC Lrp family K22225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
CSH3_k127_1574919_5 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007227 238.0
CSH3_k127_1574919_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000001736 219.0
CSH3_k127_1574919_7 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000003947 202.0
CSH3_k127_1574919_8 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000005404 195.0
CSH3_k127_1574919_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000006959 179.0
CSH3_k127_1580866_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.599e-255 803.0
CSH3_k127_1580866_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 564.0
CSH3_k127_1580866_10 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000001162 204.0
CSH3_k127_1580866_11 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000000000000000000000000000000000006398 209.0
CSH3_k127_1580866_12 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000000000000000005007 171.0
CSH3_k127_1580866_13 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000001144 169.0
CSH3_k127_1580866_15 Membrane protein, UPF0016 and UPF0016 domain-containing - - - 0.00000000000000000000000000000000000000007216 157.0
CSH3_k127_1580866_16 LUD domain - - - 0.00000000000000000000000000000000000001294 152.0
CSH3_k127_1580866_17 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000000000002379 147.0
CSH3_k127_1580866_18 SNARE associated Golgi protein K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000000000000000000000000000000000004817 145.0
CSH3_k127_1580866_19 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000002671 142.0
CSH3_k127_1580866_2 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 455.0
CSH3_k127_1580866_20 V4R K07013 - - 0.000000000002005 74.0
CSH3_k127_1580866_21 S-layer protein - - - 0.00000007536 64.0
CSH3_k127_1580866_22 Transposase K07480 - - 0.0000005318 54.0
CSH3_k127_1580866_24 Protein of unknown function (DUF3485) - - - 0.00001346 56.0
CSH3_k127_1580866_25 - - - - 0.0007747 43.0
CSH3_k127_1580866_26 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0008731 44.0
CSH3_k127_1580866_3 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 428.0
CSH3_k127_1580866_4 Thermolysin metallopeptidase, catalytic domain K01400,K08605 - 3.4.24.28,3.4.24.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 357.0
CSH3_k127_1580866_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 346.0
CSH3_k127_1580866_6 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 294.0
CSH3_k127_1580866_7 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000336 281.0
CSH3_k127_1580866_8 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008038 269.0
CSH3_k127_1580866_9 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000001055 219.0
CSH3_k127_1637364_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.573e-307 964.0
CSH3_k127_1637364_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 8.674e-243 760.0
CSH3_k127_1637364_10 Domain of unknown function (DUF366) K09139 - - 0.00000000000000000000000000000000000000000000001644 176.0
CSH3_k127_1637364_11 - - - - 0.000000000000000000000000000000004899 140.0
CSH3_k127_1637364_12 PFAM Peptidase S24 S26A S26B, conserved region K13280 - 3.4.21.89 0.0000000000000000000000003689 116.0
CSH3_k127_1637364_13 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000005942 98.0
CSH3_k127_1637364_14 - - - - 0.0000000000000001197 87.0
CSH3_k127_1637364_15 - - - - 0.000000002572 69.0
CSH3_k127_1637364_16 Right handed beta helix region - - - 0.00000003805 66.0
CSH3_k127_1637364_2 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.329e-200 638.0
CSH3_k127_1637364_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 497.0
CSH3_k127_1637364_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 460.0
CSH3_k127_1637364_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 411.0
CSH3_k127_1637364_6 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 358.0
CSH3_k127_1637364_7 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 337.0
CSH3_k127_1637364_8 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 334.0
CSH3_k127_1637364_9 - - - - 0.00000000000000000000000000000000000000000000000000009231 196.0
CSH3_k127_1655325_0 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000000000000003923 160.0
CSH3_k127_1655325_1 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000002977 152.0
CSH3_k127_1655325_2 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000344 92.0
CSH3_k127_1655325_3 CopG domain protein DNA-binding domain protein - - - 0.000000000000000007083 88.0
CSH3_k127_1655325_4 Putative zinc- or iron-chelating domain - - - 0.00000000000000006976 83.0
CSH3_k127_1655325_5 Nucleotidyltransferase domain K07075 - - 0.000000003253 59.0
CSH3_k127_1655325_6 Putative zinc- or iron-chelating domain - - - 0.000000003413 61.0
CSH3_k127_172311_0 COG1743 Adenine-specific DNA methylase containing a Zn-ribbon K07445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004782 267.0
CSH3_k127_172311_1 COG1743 Adenine-specific DNA methylase containing a Zn-ribbon K07445 - - 0.0000000000000000000000000000000000000000000000000000000000000000001321 235.0
CSH3_k127_172311_2 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.000000000000000000000000000000000000000002504 156.0
CSH3_k127_172311_3 PFAM DNA polymerase beta domain protein region K07076 - - 0.000000000000000000000000000005538 124.0
CSH3_k127_172311_4 DNA RNA helicase, superfamily II, SNF2 family - - - 0.000000000000000000000000004166 112.0
CSH3_k127_172311_5 HEPN domain - - - 0.00000000000000000001472 96.0
CSH3_k127_172311_6 DNA methylAse K07445 - - 0.000000004335 58.0
CSH3_k127_172311_7 Tellurite resistance protein TehB - - - 0.00004781 50.0
CSH3_k127_1730249_0 DNA methylase K03427 - 2.1.1.72 8.549e-306 951.0
CSH3_k127_1730249_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.127e-256 802.0
CSH3_k127_1730249_10 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.00000000000000000000000000000000000529 150.0
CSH3_k127_1730249_11 Domain of unknown function DUF123 - - - 0.000000000000000000000000000000003408 133.0
CSH3_k127_1730249_12 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000006365 133.0
CSH3_k127_1730249_13 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000001572 124.0
CSH3_k127_1730249_14 Transposase K07492 - - 0.0000000000000000000000000001308 118.0
CSH3_k127_1730249_15 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000002573 112.0
CSH3_k127_1730249_16 Transposase DDE domain - - - 0.00000000000000000000000005958 108.0
CSH3_k127_1730249_17 PFAM CBS domain containing protein - - - 0.0000000000000000000000001272 107.0
CSH3_k127_1730249_18 Binds to the 23S rRNA K02896 - - 0.000000000000000000000001682 103.0
CSH3_k127_1730249_19 Transcriptional regulator, TrmB - - - 0.00000000000000000000008579 102.0
CSH3_k127_1730249_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 452.0
CSH3_k127_1730249_20 N-6 DNA Methylase K03427 - 2.1.1.72 0.0000000000000000001178 91.0
CSH3_k127_1730249_21 Sulfurtransferase TusA - - - 0.00000000000004976 74.0
CSH3_k127_1730249_22 - - - - 0.000001295 60.0
CSH3_k127_1730249_3 nuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 385.0
CSH3_k127_1730249_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002424 294.0
CSH3_k127_1730249_5 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
CSH3_k127_1730249_6 type I restriction-modification system DNA methylase K03427 K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000004891 229.0
CSH3_k127_1730249_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000001781 226.0
CSH3_k127_1730249_8 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000003951 183.0
CSH3_k127_1730249_9 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000001045 160.0
CSH3_k127_1730309_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 564.0
CSH3_k127_1730309_1 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001041 273.0
CSH3_k127_1730309_2 KaiC K07331 - - 0.0000000000000000000000000000000000000000000000000000000000000000007831 235.0
CSH3_k127_1730309_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000001901 205.0
CSH3_k127_1730309_4 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000001183 144.0
CSH3_k127_1730309_5 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000000001436 124.0
CSH3_k127_1730309_6 Histone-like transcription factor (CBF/NF-Y) and archaeal histone - - - 0.00000000000000001023 84.0
CSH3_k127_1730309_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000152 66.0
CSH3_k127_1730382_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 604.0
CSH3_k127_1730382_1 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 430.0
CSH3_k127_1730382_2 signal transduction protein with CBS domains K07744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 373.0
CSH3_k127_1730382_3 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 355.0
CSH3_k127_1730382_4 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 333.0
CSH3_k127_1730382_5 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 292.0
CSH3_k127_1730382_6 - - - - 0.00000001339 56.0
CSH3_k127_1730382_7 Ferritin-like domain - - - 0.00003361 53.0
CSH3_k127_1753476_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.705e-234 735.0
CSH3_k127_1753476_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
CSH3_k127_1753476_2 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 306.0
CSH3_k127_1753476_3 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000002891 183.0
CSH3_k127_1753476_4 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000000003135 148.0
CSH3_k127_1753476_5 DUF35 OB-fold domain, acyl-CoA-associated K07068,K07549 - - 0.00000000002756 68.0
CSH3_k127_1753476_6 Transposase - - - 0.00000136 50.0
CSH3_k127_1753476_7 SEC-C motif - - - 0.000003041 56.0
CSH3_k127_1760813_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.213e-264 827.0
CSH3_k127_1760813_1 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 431.0
CSH3_k127_1769578_0 AMP-binding enzyme - - - 3.815e-232 724.0
CSH3_k127_1769578_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000002125 210.0
CSH3_k127_1769578_2 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000009066 190.0
CSH3_k127_1769578_3 - - - - 0.000000000000000000000005015 107.0
CSH3_k127_1769578_4 iron ion binding - - - 0.000000000000006638 75.0
CSH3_k127_1769578_5 - - - - 0.0000000001381 62.0
CSH3_k127_1770905_0 KH, type 1, domain K07041 - - 0.0 1011.0
CSH3_k127_1770905_1 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 542.0
CSH3_k127_1770905_10 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000321 226.0
CSH3_k127_1770905_11 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000000000003902 208.0
CSH3_k127_1770905_12 Domain of unknown function (DUF1724) - - - 0.00000000000000000000000000000000000000000000000000000009479 204.0
CSH3_k127_1770905_13 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000000000000000000006697 199.0
CSH3_k127_1770905_14 peptidyl-tyrosine sulfation K00525,K01768 - 1.17.4.1,4.6.1.1 0.0000000000000000000000000000000000000000000000000001086 195.0
CSH3_k127_1770905_15 - - - - 0.00000000000000000000000000000000000000000000000001002 193.0
CSH3_k127_1770905_16 ribosomal protein S15 K02956 - - 0.0000000000000000000000000000000000000000000003603 170.0
CSH3_k127_1770905_17 - - - - 0.0000000000000000000000000000007466 128.0
CSH3_k127_1770905_18 UbiA prenyltransferase family - - - 0.000000000000000000000000001218 119.0
CSH3_k127_1770905_19 MazF family transcriptional regulator K07171 - - 0.00000000000000000004086 93.0
CSH3_k127_1770905_2 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 396.0
CSH3_k127_1770905_20 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000008756 78.0
CSH3_k127_1770905_21 - - - - 0.000000000001389 76.0
CSH3_k127_1770905_22 transposase K07492 - - 0.00000000001411 69.0
CSH3_k127_1770905_23 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.0000008305 54.0
CSH3_k127_1770905_24 PBS lyase HEAT-like repeat - - - 0.000001519 59.0
CSH3_k127_1770905_25 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000004199 50.0
CSH3_k127_1770905_26 Family of unknown function (DUF5371) - - - 0.00003487 47.0
CSH3_k127_1770905_27 Transposase DDE domain - - - 0.0002323 46.0
CSH3_k127_1770905_3 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 380.0
CSH3_k127_1770905_4 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 359.0
CSH3_k127_1770905_5 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 320.0
CSH3_k127_1770905_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 298.0
CSH3_k127_1770905_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 284.0
CSH3_k127_1770905_8 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009219 276.0
CSH3_k127_1770905_9 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000000000003346 243.0
CSH3_k127_178432_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 334.0
CSH3_k127_178432_1 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 300.0
CSH3_k127_178432_2 epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003669 278.0
CSH3_k127_178432_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000006095 222.0
CSH3_k127_178432_4 Protein of unknown function (DUF473) K09135 - - 0.000000000000000000000004101 106.0
CSH3_k127_1804516_0 plastoquinone (Complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 565.0
CSH3_k127_1804516_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 543.0
CSH3_k127_1804516_10 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002774 230.0
CSH3_k127_1804516_11 Fe-S cluster K04488 - - 0.00000000000000000000000000000000000000000000000000000003032 213.0
CSH3_k127_1804516_12 Hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000001885 183.0
CSH3_k127_1804516_13 Bacterial transferase hexapeptide - - - 0.00000000000000000000000000000000000000000006932 166.0
CSH3_k127_1804516_14 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000001315 161.0
CSH3_k127_1804516_15 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000004656 160.0
CSH3_k127_1804516_16 ATP binding K06926 - - 0.00000000000000000000000000002065 120.0
CSH3_k127_1804516_17 protein conserved in archaea - - - 0.000000000000000000000000001725 124.0
CSH3_k127_1804516_18 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K12143 - - 0.00000000000000000000005592 102.0
CSH3_k127_1804516_19 - - - - 0.000000000000000005302 87.0
CSH3_k127_1804516_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 527.0
CSH3_k127_1804516_20 Rubrerythrin - - - 0.000000000000006727 75.0
CSH3_k127_1804516_21 Transposase DDE domain K07492 - - 0.00000000000006958 71.0
CSH3_k127_1804516_22 - - - - 0.000005798 51.0
CSH3_k127_1804516_23 Psort location Cytoplasmic, score 8.96 - - - 0.0001207 47.0
CSH3_k127_1804516_24 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0003058 49.0
CSH3_k127_1804516_25 - - - - 0.0003393 47.0
CSH3_k127_1804516_3 plastoquinone (Complex I) K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 513.0
CSH3_k127_1804516_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 444.0
CSH3_k127_1804516_5 Formate hydrogenlyase subunit 4 K12138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 325.0
CSH3_k127_1804516_6 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 332.0
CSH3_k127_1804516_7 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 232.0
CSH3_k127_1804516_8 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000005343 228.0
CSH3_k127_1804516_9 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000000001487 219.0
CSH3_k127_1824375_0 PFAM Prolyl oligopeptidase family - - - 3.789e-280 874.0
CSH3_k127_1824375_1 PFAM Helicase conserved C-terminal domain - - - 3.912e-218 717.0
CSH3_k127_1824375_10 - - - - 0.0000000000000002116 94.0
CSH3_k127_1824375_11 PFAM Tetratricopeptide repeat - - - 0.00000000615 66.0
CSH3_k127_1824375_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002034 287.0
CSH3_k127_1824375_3 C-5 cytosine-specific DNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007331 259.0
CSH3_k127_1824375_4 Rhodanese Homology Domain K01011,K01613 - 2.8.1.1,2.8.1.2,4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000007654 254.0
CSH3_k127_1824375_5 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
CSH3_k127_1824375_6 - - - - 0.00000000000000000000000000000000006739 143.0
CSH3_k127_1824375_7 HNH nucleases K07451 - - 0.0000000000000000000000000000000001939 138.0
CSH3_k127_1824375_8 Phospholipase D Active site motif K06131 - - 0.000000000000000000000989 106.0
CSH3_k127_1824375_9 TPR repeat-containing protein - - - 0.00000000000000000475 93.0
CSH3_k127_1864568_0 HMGL-like K01649 - 2.3.3.13 8.378e-215 672.0
CSH3_k127_1864568_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 324.0
CSH3_k127_1864568_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000002344 226.0
CSH3_k127_1864568_3 carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000004483 228.0
CSH3_k127_1864568_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000347 212.0
CSH3_k127_1864568_5 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000003163 201.0
CSH3_k127_1864568_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000001431 112.0
CSH3_k127_1864568_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000002359 95.0
CSH3_k127_189811_0 COG1002 Type II restriction enzyme, methylase subunits - - - 3.41e-207 687.0
CSH3_k127_189811_1 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 484.0
CSH3_k127_189811_2 ATPase, AAA superfamily K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 431.0
CSH3_k127_189811_3 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 287.0
CSH3_k127_189811_4 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000001919 142.0
CSH3_k127_189811_5 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000001983 119.0
CSH3_k127_1953418_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 610.0
CSH3_k127_1953418_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 573.0
CSH3_k127_1953418_10 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001519 71.0
CSH3_k127_1953418_11 Psort location Cytoplasmic, score - - - 0.0000000001711 62.0
CSH3_k127_1953418_12 DDE superfamily endonuclease - - - 0.0000000009836 59.0
CSH3_k127_1953418_13 to GB L77117 SP Q57808 PID 1499149 percent identity - - - 0.000000004335 58.0
CSH3_k127_1953418_14 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000002426 61.0
CSH3_k127_1953418_2 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 557.0
CSH3_k127_1953418_3 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000333 233.0
CSH3_k127_1953418_4 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000003761 201.0
CSH3_k127_1953418_5 to percent identity - - - 0.00000000000000000000000000000000000000000000000000000006487 206.0
CSH3_k127_1953418_6 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000005061 149.0
CSH3_k127_1953418_7 Subtilase family K17734 - - 0.0000000000000000000000000000000002139 145.0
CSH3_k127_1953418_8 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000001156 109.0
CSH3_k127_1953418_9 COG0433 Predicted ATPase - - - 0.0000000000001134 74.0
CSH3_k127_1961002_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1119.0
CSH3_k127_1961002_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 587.0
CSH3_k127_1961002_2 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 457.0
CSH3_k127_1961002_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 418.0
CSH3_k127_1961002_4 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 336.0
CSH3_k127_1961002_5 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 318.0
CSH3_k127_1961002_6 amidohydrolase - - - 0.0000000001021 74.0
CSH3_k127_1968293_0 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0 1367.0
CSH3_k127_1968293_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1294.0
CSH3_k127_1968293_10 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004711 305.0
CSH3_k127_1968293_11 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001651 263.0
CSH3_k127_1968293_12 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000001139 242.0
CSH3_k127_1968293_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000003806 202.0
CSH3_k127_1968293_14 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000001422 186.0
CSH3_k127_1968293_15 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000001693 196.0
CSH3_k127_1968293_16 - - - - 0.000000000000000000000000000000000000005588 148.0
CSH3_k127_1968293_17 InterPro IPR007367 - - - 0.000000000000000000000000000001636 121.0
CSH3_k127_1968293_18 TPR repeat-containing protein - - - 0.000000000000000000000000000145 127.0
CSH3_k127_1968293_19 Transposase K07492 - - 0.000000000000000000000001707 106.0
CSH3_k127_1968293_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1079.0
CSH3_k127_1968293_20 PFAM PKD domain containing protein - - - 0.000000000000000000000001873 121.0
CSH3_k127_1968293_21 Transposase - - - 0.00000000007469 64.0
CSH3_k127_1968293_22 Putative zinc- or iron-chelating domain K06940 - - 0.000000002353 65.0
CSH3_k127_1968293_23 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0001022 51.0
CSH3_k127_1968293_24 protein FAR1-RELATED SEQUENCE - - - 0.0007536 51.0
CSH3_k127_1968293_3 HsdM N-terminal domain - - - 1.874e-285 885.0
CSH3_k127_1968293_4 ATPases associated with a variety of cellular activities K00400 - - 1.908e-202 644.0
CSH3_k127_1968293_5 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 447.0
CSH3_k127_1968293_6 Type I restriction K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 401.0
CSH3_k127_1968293_7 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 378.0
CSH3_k127_1968293_8 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 343.0
CSH3_k127_1968293_9 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 320.0
CSH3_k127_1968388_0 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 423.0
CSH3_k127_1968388_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000007939 242.0
CSH3_k127_1968388_10 - - - - 0.0000008978 54.0
CSH3_k127_1968388_11 COG1943 Transposase and inactivated derivatives K07491 - - 0.000001234 53.0
CSH3_k127_1968388_12 Probable transposase K07496 - - 0.000003361 53.0
CSH3_k127_1968388_13 AAA-like domain K06915 - - 0.00006952 57.0
CSH3_k127_1968388_14 G-rich domain on putative tyrosine kinase K16554 - - 0.0003895 51.0
CSH3_k127_1968388_2 - - - - 0.000000000000000000000000000000000002586 141.0
CSH3_k127_1968388_3 ATPase involved in DNA repair - - - 0.000000000000000000000000007102 127.0
CSH3_k127_1968388_4 COG1467 Eukaryotic-type DNA primase, catalytic (small) subunit - - - 0.0000000000000000000000008342 115.0
CSH3_k127_1968388_5 Probable transposase K07496 - - 0.0000000000000000000005121 100.0
CSH3_k127_1968388_6 COGs COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000832 80.0
CSH3_k127_1968388_7 COG0714 MoxR-like ATPases K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000004001 73.0
CSH3_k127_1968388_8 Zinc finger SWIM domain protein - - - 0.0000000006789 68.0
CSH3_k127_1968388_9 COG4962 Flp pilus assembly protein, ATPase CpaF K02283 - - 0.000000002428 71.0
CSH3_k127_1997391_0 MviN-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 608.0
CSH3_k127_1997391_1 Uncharacterized protein conserved in archaea (DUF2114) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 589.0
CSH3_k127_1997391_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005005 280.0
CSH3_k127_1997391_11 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
CSH3_k127_1997391_12 Cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002002 239.0
CSH3_k127_1997391_13 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002943 238.0
CSH3_k127_1997391_14 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000422 207.0
CSH3_k127_1997391_15 Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000001075 178.0
CSH3_k127_1997391_16 PFAM conserved - - - 0.0000000000000000000000000000000000000009368 152.0
CSH3_k127_1997391_17 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000001375 138.0
CSH3_k127_1997391_18 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000175 138.0
CSH3_k127_1997391_19 - - - - 0.000000000000000000000000000003669 134.0
CSH3_k127_1997391_2 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 517.0
CSH3_k127_1997391_20 Domain of unknown function (DUF1894) - - - 0.000000000006114 69.0
CSH3_k127_1997391_3 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 496.0
CSH3_k127_1997391_4 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing K08068,K18429 - 3.2.1.183,3.2.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 454.0
CSH3_k127_1997391_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 394.0
CSH3_k127_1997391_6 synthase K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 392.0
CSH3_k127_1997391_7 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 389.0
CSH3_k127_1997391_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 331.0
CSH3_k127_1997391_9 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 325.0
CSH3_k127_2093046_0 Heat shock 70 kDa protein K04043 - - 1.01e-269 842.0
CSH3_k127_2093046_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 574.0
CSH3_k127_2093046_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000003564 213.0
CSH3_k127_2093046_11 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000009831 194.0
CSH3_k127_2093046_12 archaeal Zn-finger protein - - - 0.00000000000000000000000000000000000003911 152.0
CSH3_k127_2093046_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000001044 148.0
CSH3_k127_2093046_14 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000002308 133.0
CSH3_k127_2093046_15 DDE superfamily endonuclease - - - 0.00000000000000000000000000004017 118.0
CSH3_k127_2093046_16 - - - - 0.0000000000000000000001426 111.0
CSH3_k127_2093046_17 - - - - 0.00000000000000000002734 94.0
CSH3_k127_2093046_18 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000001071 88.0
CSH3_k127_2093046_19 DDE superfamily endonuclease - - - 0.00000002159 55.0
CSH3_k127_2093046_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 425.0
CSH3_k127_2093046_20 PFAM SMP-30 Gluconolaconase - - - 0.0000002052 55.0
CSH3_k127_2093046_21 DDE superfamily endonuclease - - - 0.0000007625 51.0
CSH3_k127_2093046_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 421.0
CSH3_k127_2093046_4 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 405.0
CSH3_k127_2093046_5 DNA polymerase beta domain protein region K09717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 381.0
CSH3_k127_2093046_6 PINc domain ribonuclease K09006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 315.0
CSH3_k127_2093046_7 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 297.0
CSH3_k127_2093046_8 ATP-grasp domain K06914 - 6.3.4.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003734 277.0
CSH3_k127_2093046_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000004241 240.0
CSH3_k127_2093076_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 477.0
CSH3_k127_2093076_1 SMART Elongator protein 3 MiaB NifB K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 366.0
CSH3_k127_2093076_2 Transcriptional regulator - - - 0.00000000000000000000000000000000001291 139.0
CSH3_k127_2093076_3 transposition, DNA-mediated - - - 0.000000000001702 73.0
CSH3_k127_2212543_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 384.0
CSH3_k127_2212543_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 355.0
CSH3_k127_2212543_10 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000004605 137.0
CSH3_k127_2212543_11 PFAM helix-turn-helix domain protein K07729 - - 0.0000000000000000000000005766 105.0
CSH3_k127_2212543_12 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.0000000000000000000006976 96.0
CSH3_k127_2212543_13 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.000000000000000003737 94.0
CSH3_k127_2212543_14 ABC transporter (Permease) K01992 - - 0.00009277 45.0
CSH3_k127_2212543_15 COG3316 Transposase and inactivated derivatives K07498 - - 0.0002299 47.0
CSH3_k127_2212543_16 - - - - 0.0002609 48.0
CSH3_k127_2212543_17 to percent identity - - - 0.0005948 42.0
CSH3_k127_2212543_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 318.0
CSH3_k127_2212543_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000007222 266.0
CSH3_k127_2212543_4 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003433 266.0
CSH3_k127_2212543_5 Transposase zinc-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001361 256.0
CSH3_k127_2212543_6 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000004427 237.0
CSH3_k127_2212543_7 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000788 206.0
CSH3_k127_2212543_8 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000004096 182.0
CSH3_k127_2212543_9 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000003887 145.0
CSH3_k127_226969_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 410.0
CSH3_k127_226969_1 Aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000001519 156.0
CSH3_k127_226969_2 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000003156 136.0
CSH3_k127_226969_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000000000000000000005835 109.0
CSH3_k127_226969_4 S-layer protein - - - 0.000000000003282 73.0
CSH3_k127_226969_5 COG3385 FOG Transposase and inactivated derivatives - - - 0.000000000004851 66.0
CSH3_k127_226969_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0004857 43.0
CSH3_k127_237557_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 551.0
CSH3_k127_237557_1 Peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
CSH3_k127_237557_10 COG1943 Transposase and inactivated derivatives K07491 - - 0.0001109 46.0
CSH3_k127_237557_2 PFAM Glycosyl transferase family 2 K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 328.0
CSH3_k127_237557_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 337.0
CSH3_k127_237557_4 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000008633 222.0
CSH3_k127_237557_5 - - - - 0.00000000000000000000000000000000000000001385 156.0
CSH3_k127_237557_6 Family of unknown function (DUF5402) - - - 0.0000000000000000000000000000000000000009999 151.0
CSH3_k127_237557_8 - - - - 0.0000000000000000000000002417 121.0
CSH3_k127_237557_9 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000419 49.0
CSH3_k127_237559_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1489.0
CSH3_k127_237559_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.216e-294 915.0
CSH3_k127_237559_2 TPR Domain containing protein - - - 0.00000000000000000000000000000000000000008421 160.0
CSH3_k127_237559_3 Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - 0.00000000000000000000005705 103.0
CSH3_k127_237559_4 Nucleotidyltransferase domain - - - 0.0000000000002416 74.0
CSH3_k127_237559_5 Transposase IS200 like K07491 - - 0.0000000000004962 72.0
CSH3_k127_237559_7 Cytochrome c K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 0.0000001493 54.0
CSH3_k127_237559_8 PFAM NADPH-dependent FMN reductase - - - 0.0001172 44.0
CSH3_k127_2383922_0 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000003403 176.0
CSH3_k127_2383922_1 Product type e enzyme K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000007016 161.0
CSH3_k127_2383922_2 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000006252 138.0
CSH3_k127_2383922_3 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000002368 117.0
CSH3_k127_2383922_4 Product type e enzyme K03427 - 2.1.1.72 0.0000000000000000000000000009062 111.0
CSH3_k127_2383922_5 DNA polymerase beta K07076 - - 0.00000000000000000000001822 107.0
CSH3_k127_2383922_6 HEPN domain - - - 0.0000000000000000000008137 101.0
CSH3_k127_2383922_7 N-6 DNA methylase K03427 - 2.1.1.72 0.000000000000000009446 85.0
CSH3_k127_2383922_8 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000005129 80.0
CSH3_k127_2383922_9 type I restriction modification DNA specificity domain K01153,K01154 - 3.1.21.3 0.000000009088 59.0
CSH3_k127_2390183_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000004068 197.0
CSH3_k127_2390183_1 - - - - 0.000000000000000000000000000000000000000007529 159.0
CSH3_k127_2390183_2 Nucleotidyltransferase domain - - - 0.000000000000000000000000000003703 122.0
CSH3_k127_2390183_3 HEPN domain - - - 0.000000000000000000000000002974 113.0
CSH3_k127_2390183_4 nucleic acid-binding protein, contains PIN domain K07065 - - 0.00000000000000000000000006032 111.0
CSH3_k127_2390183_5 - - - - 0.0000000000000000000004987 108.0
CSH3_k127_2390183_6 mRNA binding - - - 0.0000000005498 63.0
CSH3_k127_2390183_7 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000931 46.0
CSH3_k127_2390183_8 - - - - 0.000355 46.0
CSH3_k127_2450446_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.114e-211 664.0
CSH3_k127_2450446_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 293.0
CSH3_k127_2450446_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000005083 130.0
CSH3_k127_2450446_3 Iron-sulphur cluster biosynthesis K15724 - - 0.00000000000000000000000000001081 122.0
CSH3_k127_2475896_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 606.0
CSH3_k127_2475896_1 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 524.0
CSH3_k127_2475896_10 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000002067 110.0
CSH3_k127_2475896_11 CAAX protease self-immunity K07052 - - 0.00000000000000001333 89.0
CSH3_k127_2475896_12 to percent identity - - - 0.00000000002165 66.0
CSH3_k127_2475896_13 - - - - 0.0000000003732 64.0
CSH3_k127_2475896_14 - - - - 0.000000001455 62.0
CSH3_k127_2475896_15 TIR domain - - - 0.00000005669 59.0
CSH3_k127_2475896_16 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0004188 49.0
CSH3_k127_2475896_2 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 458.0
CSH3_k127_2475896_3 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 368.0
CSH3_k127_2475896_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 338.0
CSH3_k127_2475896_5 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000878 286.0
CSH3_k127_2475896_6 Belongs to the acylphosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000009723 213.0
CSH3_k127_2475896_7 to orf3 of fosmid clone 4B7mr3 - - - 0.0000000000000000000000000000000000000000000000000000004249 209.0
CSH3_k127_2475896_8 FeoA K03709 - - 0.0000000000000000000000000000000000000000000000008364 181.0
CSH3_k127_2475896_9 Permease family K06901 - - 0.00000000000000000000000000000000000001575 160.0
CSH3_k127_2535623_0 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 5.291e-241 760.0
CSH3_k127_2535623_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 573.0
CSH3_k127_2535623_10 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009122 253.0
CSH3_k127_2535623_11 Domain of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000001097 219.0
CSH3_k127_2535623_12 Psort location Cytoplasmic, score K00027,K22212 - 1.1.1.38,4.1.1.101 0.0000000000000000000000000000000000000000000000000000000000005678 213.0
CSH3_k127_2535623_13 - - - - 0.00000000000000000000000000000000000000003264 158.0
CSH3_k127_2535623_14 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000000000135 143.0
CSH3_k127_2535623_15 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000002568 144.0
CSH3_k127_2535623_16 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.0000259 53.0
CSH3_k127_2535623_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 542.0
CSH3_k127_2535623_3 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 467.0
CSH3_k127_2535623_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 387.0
CSH3_k127_2535623_5 oligopeptide dipeptide ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 352.0
CSH3_k127_2535623_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 324.0
CSH3_k127_2535623_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 297.0
CSH3_k127_2535623_8 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002633 271.0
CSH3_k127_2535623_9 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000005532 265.0
CSH3_k127_2575167_0 tetratricopeptide - - - 5.665e-234 755.0
CSH3_k127_2575167_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 512.0
CSH3_k127_2575167_10 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000223 185.0
CSH3_k127_2575167_11 CHAT domain - - - 0.0000000000000000000000000000000000000000000000004837 201.0
CSH3_k127_2575167_12 PFAM 4-vinyl reductase, 4VR K07013 - - 0.00000000000000000000000000000000000003196 153.0
CSH3_k127_2575167_13 Aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000005289 149.0
CSH3_k127_2575167_14 metal ion binding - - - 0.0000000000000000000000000000005068 126.0
CSH3_k127_2575167_15 Flavodoxin - - - 0.00000000000000000000000001013 117.0
CSH3_k127_2575167_16 ISXO2-like transposase domain - - - 0.000000000000000000001022 97.0
CSH3_k127_2575167_17 Belongs to the UPF0235 family K09131 - - 0.000000000000000000001226 97.0
CSH3_k127_2575167_18 Tesmin/TSO1-like CXC domain - - - 0.000000000000000000002399 99.0
CSH3_k127_2575167_19 rubredoxin - - - 0.000000000000000000003175 93.0
CSH3_k127_2575167_2 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 467.0
CSH3_k127_2575167_20 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000003361 83.0
CSH3_k127_2575167_21 transposition, DNA-mediated - - - 0.0000000000002679 71.0
CSH3_k127_2575167_22 transposition, DNA-mediated - - - 0.00000000003861 64.0
CSH3_k127_2575167_23 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000003071 61.0
CSH3_k127_2575167_24 Transcriptional regulator K03655 - 3.6.4.12 0.000000002783 60.0
CSH3_k127_2575167_25 RibD C-terminal domain - - - 0.00004461 47.0
CSH3_k127_2575167_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 400.0
CSH3_k127_2575167_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 375.0
CSH3_k127_2575167_5 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 334.0
CSH3_k127_2575167_6 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001875 272.0
CSH3_k127_2575167_7 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003196 250.0
CSH3_k127_2575167_8 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000002592 227.0
CSH3_k127_2575167_9 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000002669 203.0
CSH3_k127_2598434_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 1.533e-250 792.0
CSH3_k127_2598434_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 550.0
CSH3_k127_2598434_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 505.0
CSH3_k127_2598434_3 PFAM Circadian clock protein KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 333.0
CSH3_k127_2598434_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001222 260.0
CSH3_k127_2598434_5 DDE superfamily endonuclease - - - 0.00000000000861 66.0
CSH3_k127_2598434_6 Protein of unknown function (DUF1670) - - - 0.00003243 50.0
CSH3_k127_2605258_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 342.0
CSH3_k127_2605258_1 CRISPR-associated endoribonuclease Cas6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000152 282.0
CSH3_k127_2605258_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000006731 186.0
CSH3_k127_2605258_3 - K19122 - - 0.000000000000000000000000000001468 131.0
CSH3_k127_2605258_4 TIGRFAM CRISPR locus-related DNA-binding protein K07725 - - 0.000000000000000000000000000003468 128.0
CSH3_k127_2605258_5 Transposase IS200 like K07491 - - 0.00002792 49.0
CSH3_k127_2612168_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 565.0
CSH3_k127_2612168_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 490.0
CSH3_k127_2612168_2 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 383.0
CSH3_k127_2612168_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 303.0
CSH3_k127_2612168_4 - - - - 0.0000000000000004637 89.0
CSH3_k127_2668262_0 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 607.0
CSH3_k127_2668262_1 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 534.0
CSH3_k127_2668262_10 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004604 259.0
CSH3_k127_2668262_11 STAS domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
CSH3_k127_2668262_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000001959 174.0
CSH3_k127_2668262_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000001073 170.0
CSH3_k127_2668262_14 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.000000000000000000000000000000000000004873 149.0
CSH3_k127_2668262_15 transporter antisigma-factor antagonist STAS K17763 - - 0.000000000000000000000000000000000006718 147.0
CSH3_k127_2668262_16 phosphoserine phosphatase activity K05518,K07315 - 3.1.3.3 0.000000000000000000000000000000000009987 144.0
CSH3_k127_2668262_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000005908 142.0
CSH3_k127_2668262_18 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000009164 121.0
CSH3_k127_2668262_19 - - - - 0.0000000000000000000000000002122 116.0
CSH3_k127_2668262_2 Rhodopirellula transposase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 481.0
CSH3_k127_2668262_20 - - - - 0.000000000000000000000000004047 117.0
CSH3_k127_2668262_21 STAS domain K17762 - - 0.000000000000000000000000004814 114.0
CSH3_k127_2668262_22 Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.0000000000000000001353 105.0
CSH3_k127_2668262_23 - - - - 0.0000000000000000009074 94.0
CSH3_k127_2668262_24 Domain of unknown function - - - 0.0000000000009093 83.0
CSH3_k127_2668262_25 GAF domain - - - 0.0000000004197 72.0
CSH3_k127_2668262_26 PFAM EamA-like transporter family K08978 - - 0.0000002574 57.0
CSH3_k127_2668262_27 glycoside hydrolase, family - - - 0.00000152 62.0
CSH3_k127_2668262_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 326.0
CSH3_k127_2668262_4 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 316.0
CSH3_k127_2668262_5 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 321.0
CSH3_k127_2668262_6 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 292.0
CSH3_k127_2668262_7 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 314.0
CSH3_k127_2668262_8 KaiC K07331 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002992 276.0
CSH3_k127_2668262_9 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000019 281.0
CSH3_k127_2668298_0 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange - - - 0.0000000000000000000000000000000000000000000000000000000000000006482 230.0
CSH3_k127_2668298_1 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000001998 156.0
CSH3_k127_2705981_0 RNA methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 320.0
CSH3_k127_2705981_1 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 288.0
CSH3_k127_2705981_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005533 263.0
CSH3_k127_2705981_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001015 265.0
CSH3_k127_2705981_4 Belongs to the UPF0212 family K09731 - - 0.0000000000000000000000000000000000000000001991 161.0
CSH3_k127_2705981_5 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000003087 116.0
CSH3_k127_2705981_6 PFAM Insertion element protein K07488 - - 0.000000628 56.0
CSH3_k127_2705981_7 ISXO2-like transposase domain - - - 0.00006045 46.0
CSH3_k127_2707076_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 591.0
CSH3_k127_2707076_1 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000003447 222.0
CSH3_k127_2708492_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.93e-245 772.0
CSH3_k127_2708492_1 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.311e-228 715.0
CSH3_k127_2708492_10 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 361.0
CSH3_k127_2708492_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 346.0
CSH3_k127_2708492_12 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 336.0
CSH3_k127_2708492_13 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 284.0
CSH3_k127_2708492_14 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003634 267.0
CSH3_k127_2708492_15 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000000000033 224.0
CSH3_k127_2708492_16 Heterodisulfide reductase subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000003374 213.0
CSH3_k127_2708492_17 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000006611 189.0
CSH3_k127_2708492_18 - - - - 0.000000000000000000000000000000003448 145.0
CSH3_k127_2708492_19 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000001391 125.0
CSH3_k127_2708492_2 - - - - 4.261e-226 717.0
CSH3_k127_2708492_20 HEPN domain - - - 0.00000000000000000000000000003356 120.0
CSH3_k127_2708492_21 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000003302 93.0
CSH3_k127_2708492_22 - - - - 0.0000000000000000001858 91.0
CSH3_k127_2708492_23 Belongs to the acylphosphatase family - - - 0.00000000000000002693 90.0
CSH3_k127_2708492_24 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000005002 63.0
CSH3_k127_2708492_25 - - - - 0.000000006154 58.0
CSH3_k127_2708492_26 Nucleotidyltransferase domain K07076 - - 0.00000003815 62.0
CSH3_k127_2708492_27 hydrocarbon binding protein (contains V4R domain) - - - 0.000001723 55.0
CSH3_k127_2708492_3 Type II/IV secretion system protein - - - 7.164e-217 696.0
CSH3_k127_2708492_4 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 9.436e-205 640.0
CSH3_k127_2708492_5 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 589.0
CSH3_k127_2708492_6 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 540.0
CSH3_k127_2708492_7 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 526.0
CSH3_k127_2708492_8 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 446.0
CSH3_k127_2708492_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 454.0
CSH3_k127_27349_0 Transport of potassium into the cell K03549 - - 2.328e-245 771.0
CSH3_k127_27349_1 TGS domain protein K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 507.0
CSH3_k127_27349_10 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000007712 195.0
CSH3_k127_27349_11 - - - - 0.000000000000000000000000000000000000001004 162.0
CSH3_k127_27349_12 Uncharacterised protein family UPF0058 - - - 0.00000000000000000000000000006097 118.0
CSH3_k127_27349_13 - - - - 0.000000000000000000000001513 111.0
CSH3_k127_27349_14 - - - - 0.0000000000000003635 87.0
CSH3_k127_27349_15 - - - - 0.0000000000000003684 92.0
CSH3_k127_27349_16 Roadblock LC7 family protein K07131 - - 0.000000000000001695 81.0
CSH3_k127_27349_17 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000001278 72.0
CSH3_k127_27349_18 - - - - 0.0000000000006437 79.0
CSH3_k127_27349_19 Peptidase S24-like K13280 GO:0003674,GO:0003824,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 3.4.21.89 0.0000005068 60.0
CSH3_k127_27349_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 490.0
CSH3_k127_27349_3 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 472.0
CSH3_k127_27349_4 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 428.0
CSH3_k127_27349_5 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 341.0
CSH3_k127_27349_6 ATPases associated with a variety of cellular activities K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 299.0
CSH3_k127_27349_7 Molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008165 283.0
CSH3_k127_27349_8 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002503 245.0
CSH3_k127_27349_9 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000006978 229.0
CSH3_k127_2741024_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000768 269.0
CSH3_k127_2741024_1 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000613 218.0
CSH3_k127_2741024_2 RAMP superfamily K19140 - - 0.00000000000000001749 86.0
CSH3_k127_2761965_0 Heat shock 70 kDa protein - - - 1.976e-230 725.0
CSH3_k127_2761965_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 2.398e-194 617.0
CSH3_k127_2761965_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000002653 221.0
CSH3_k127_2761965_3 - - - - 0.000000000000000000000000000000000000000000000000001783 186.0
CSH3_k127_2761965_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687,K04043 - - 0.0000000000000000000000000000000000000000000004152 176.0
CSH3_k127_2761965_5 transposition, DNA-mediated - - - 0.00000000000000000000000000000000000000000001265 166.0
CSH3_k127_2761965_6 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000001007 153.0
CSH3_k127_2761965_7 - - - - 0.00000000001471 65.0
CSH3_k127_2761965_8 PFAM Nitrate reductase gamma subunit - - - 0.00000000001978 74.0
CSH3_k127_2771735_0 Gaf domain K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000003942 179.0
CSH3_k127_277942_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 283.0
CSH3_k127_277942_1 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002513 286.0
CSH3_k127_277942_2 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000006636 64.0
CSH3_k127_2779680_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 1.378e-316 983.0
CSH3_k127_2779680_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 372.0
CSH3_k127_278789_0 PFAM peptidase U32 K08303 - - 4.661e-210 678.0
CSH3_k127_278789_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 594.0
CSH3_k127_278789_10 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000006434 192.0
CSH3_k127_278789_11 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000001187 169.0
CSH3_k127_278789_12 COG1994 Zn-dependent proteases - - - 0.0000000000000000000000000000000000009202 148.0
CSH3_k127_278789_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000000000000000000000004402 124.0
CSH3_k127_278789_14 ThiS family K03636 - - 0.000000000000000003227 89.0
CSH3_k127_278789_15 arsenical-resistance protein K03325,K03741 - 1.20.4.1 0.0000000000000008113 77.0
CSH3_k127_278789_16 Phage integrase family - - - 0.00000000000009521 78.0
CSH3_k127_278789_17 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000003463 54.0
CSH3_k127_278789_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 464.0
CSH3_k127_278789_3 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 404.0
CSH3_k127_278789_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 371.0
CSH3_k127_278789_5 PFAM Queuosine biosynthesis protein K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 360.0
CSH3_k127_278789_6 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 344.0
CSH3_k127_278789_7 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001779 280.0
CSH3_k127_278789_8 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000001126 233.0
CSH3_k127_278789_9 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000008482 214.0
CSH3_k127_2832475_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1174.0
CSH3_k127_2832475_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 7.764e-214 683.0
CSH3_k127_2832475_10 RNA binding K07581 - - 0.0000000000000000000000000002157 119.0
CSH3_k127_2832475_11 Parallel beta-helix - - - 0.0000000000000000000000000004584 134.0
CSH3_k127_2832475_12 Subtilase family K17734 - - 0.0000000000000000000000000006038 133.0
CSH3_k127_2832475_13 HupF/HypC family K04653 - - 0.0000000000000000000146 93.0
CSH3_k127_2832475_14 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000007097 73.0
CSH3_k127_2832475_15 PFAM MULE transposase, conserved domain - - - 0.0000000000002171 76.0
CSH3_k127_2832475_16 MULE transposase domain - - - 0.0000000000005132 73.0
CSH3_k127_2832475_17 AI-2E family transporter - - - 0.000000000005204 77.0
CSH3_k127_2832475_18 Thiol disulfide interchange protein K03673 - - 0.0000000272 63.0
CSH3_k127_2832475_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 600.0
CSH3_k127_2832475_3 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 385.0
CSH3_k127_2832475_4 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001217 281.0
CSH3_k127_2832475_5 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
CSH3_k127_2832475_6 carbohydrate binding K00702 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000001755 250.0
CSH3_k127_2832475_7 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.000000000000000000000000000000000001862 142.0
CSH3_k127_2832475_8 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000007758 144.0
CSH3_k127_2832475_9 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.00000000000000000000000000000000153 131.0
CSH3_k127_286841_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.075e-289 903.0
CSH3_k127_286841_1 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 331.0
CSH3_k127_286841_2 SNARE associated Golgi protein K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000000000000001521 85.0
CSH3_k127_2871391_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.157e-265 831.0
CSH3_k127_2871391_1 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 419.0
CSH3_k127_2871391_10 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000000000000221 93.0
CSH3_k127_2871391_11 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.0000000000002549 72.0
CSH3_k127_2871391_12 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000005382 74.0
CSH3_k127_2871391_13 xylanase chitin deacetylase K22278 - 3.5.1.104 0.00000000003763 69.0
CSH3_k127_2871391_14 - - - - 0.00000001552 59.0
CSH3_k127_2871391_15 RNA methylase K07446 - 2.1.1.213 0.00001091 48.0
CSH3_k127_2871391_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 400.0
CSH3_k127_2871391_3 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 341.0
CSH3_k127_2871391_4 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 333.0
CSH3_k127_2871391_5 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000001049 209.0
CSH3_k127_2871391_6 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000009477 132.0
CSH3_k127_2871391_7 - - - - 0.000000000000000000000000000000005902 136.0
CSH3_k127_2871391_9 von Willebrand factor, type A K07114 - - 0.00000000000000000007026 98.0
CSH3_k127_2929570_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 7.664e-257 802.0
CSH3_k127_2929570_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 3.969e-228 715.0
CSH3_k127_2929570_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
CSH3_k127_2929570_3 Integrase core domain K07497 - - 0.0000000000000000000001634 103.0
CSH3_k127_2929570_4 - - - - 0.000000000000000001476 87.0
CSH3_k127_2932279_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 326.0
CSH3_k127_2932279_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000002284 205.0
CSH3_k127_2932279_2 response regulator, receiver - - - 0.0000000000000000000000000000000004672 143.0
CSH3_k127_2932279_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000004136 123.0
CSH3_k127_2932742_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001065 268.0
CSH3_k127_2932742_1 iron dependent repressor - - - 0.00000006214 65.0
CSH3_k127_2937751_0 - K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001337 292.0
CSH3_k127_2937751_1 Nucleotidyltransferase domain - - - 0.0000000000000000001323 93.0
CSH3_k127_2937751_2 HEPN domain - - - 0.000000001022 61.0
CSH3_k127_2937751_3 Rhodopirellula transposase family protein - - - 0.0004585 44.0
CSH3_k127_2971030_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1130.0
CSH3_k127_2971030_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 455.0
CSH3_k127_2971030_10 Belongs to the peptidase S16 family K06870 - - 0.0000000000000002214 89.0
CSH3_k127_2971030_11 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000007332 81.0
CSH3_k127_2971030_12 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000077 77.0
CSH3_k127_2971030_13 PFAM RNA-binding protein K06964 - - 0.0002429 45.0
CSH3_k127_2971030_2 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 278.0
CSH3_k127_2971030_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
CSH3_k127_2971030_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000001151 222.0
CSH3_k127_2971030_5 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000000000000000001985 155.0
CSH3_k127_2971030_6 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000001242 142.0
CSH3_k127_2971030_7 GDYXXLXY protein - - - 0.00000000000000000001117 98.0
CSH3_k127_2971030_8 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000001691 108.0
CSH3_k127_2971030_9 amine dehydrogenase activity - - - 0.0000000000000000002189 100.0
CSH3_k127_2995701_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 433.0
CSH3_k127_2995701_1 nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 353.0
CSH3_k127_2995701_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000001516 111.0
CSH3_k127_2995701_3 S-layer protein - - - 0.0000000000000005664 85.0
CSH3_k127_2995701_4 FR47-like protein - - - 0.000005859 59.0
CSH3_k127_300701_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.886e-217 681.0
CSH3_k127_300701_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.9e-216 679.0
CSH3_k127_300701_10 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 342.0
CSH3_k127_300701_11 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 325.0
CSH3_k127_300701_12 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
CSH3_k127_300701_13 Segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000000000001262 200.0
CSH3_k127_300701_14 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000001505 198.0
CSH3_k127_300701_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001071 188.0
CSH3_k127_300701_16 Transcriptional regulator, TrmB - - - 0.000000000000000000000000000000000004064 140.0
CSH3_k127_300701_17 Hep Hag repeat protein - - - 0.0000000000000000000000000000003373 136.0
CSH3_k127_300701_18 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001655 111.0
CSH3_k127_300701_19 Transposase IS66 family - - - 0.000004933 49.0
CSH3_k127_300701_2 PFAM dihydropteroate synthase, DHPS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 497.0
CSH3_k127_300701_3 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 453.0
CSH3_k127_300701_4 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 430.0
CSH3_k127_300701_5 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
CSH3_k127_300701_6 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 399.0
CSH3_k127_300701_7 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 387.0
CSH3_k127_300701_8 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 367.0
CSH3_k127_300701_9 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 358.0
CSH3_k127_3014360_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 424.0
CSH3_k127_3014360_1 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000001198 190.0
CSH3_k127_3014360_2 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441,K22174 - 1.1.98.4,1.12.98.1 0.00000000000000000000000000000000000000000000000001127 198.0
CSH3_k127_3014360_3 - - - - 0.00000000000000000000000000000000000000000000001148 189.0
CSH3_k127_3014360_4 - - - - 0.0000000000000000000000000000000000000000002857 176.0
CSH3_k127_3018299_0 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.0000000000000000000000000000000000000000000000000000000000001461 222.0
CSH3_k127_3018299_1 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.0000000006331 68.0
CSH3_k127_3018427_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 479.0
CSH3_k127_3018427_1 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001513 280.0
CSH3_k127_3018427_10 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000003774 103.0
CSH3_k127_3018427_11 SigmaK-factor processing regulatory protein BofA - - - 0.00000007591 57.0
CSH3_k127_3018427_12 - - - - 0.00002583 53.0
CSH3_k127_3018427_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000001904 267.0
CSH3_k127_3018427_3 xylanase chitin deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000001091 214.0
CSH3_k127_3018427_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000006805 217.0
CSH3_k127_3018427_5 PFAM TfuA domain protein, core - - - 0.00000000000000000000000000000000000000000000000000000003608 203.0
CSH3_k127_3018427_6 CMP dCMP deaminase, zinc-binding K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000001202 196.0
CSH3_k127_3018427_7 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.0000000000000000000000000000000000000003652 155.0
CSH3_k127_3018427_8 Acetyltransferase (GNAT) family K21935 - 2.3.1.264 0.000000000000000000000000000000000003192 139.0
CSH3_k127_3018427_9 B-block binding subunit of TFIIIC - - - 0.0000000000000000000000001425 109.0
CSH3_k127_3021549_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 6.004e-254 795.0
CSH3_k127_3021549_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 5.649e-238 751.0
CSH3_k127_3021549_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000002003 115.0
CSH3_k127_3021549_3 Domain of unknown function (DUF4158) - - - 0.000003452 52.0
CSH3_k127_3069999_0 PFAM O-methyltransferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000007749 204.0
CSH3_k127_3069999_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000001008 186.0
CSH3_k127_3069999_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000003057 156.0
CSH3_k127_3069999_3 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000002244 122.0
CSH3_k127_3069999_4 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000001641 101.0
CSH3_k127_3069999_5 Protein of unknown function (DUF2953) - - - 0.0000003791 59.0
CSH3_k127_3069999_6 extracellular matrix structural constituent K12287 - - 0.0004003 48.0
CSH3_k127_3141032_0 COG1138 Cytochrome c biogenesis factor K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 331.0
CSH3_k127_3141032_1 COG0785 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000002555 141.0
CSH3_k127_3141032_2 Subtilase family K17734 - - 0.0000000000000000000000000574 115.0
CSH3_k127_3141032_3 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000005522 101.0
CSH3_k127_3141032_4 Thioredoxin-like - - - 0.0000000000001897 76.0
CSH3_k127_3160222_0 acid binding OB-fold tRNA helicase-type K07463 - - 7.957e-273 857.0
CSH3_k127_3160222_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.487e-254 793.0
CSH3_k127_3160222_10 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001579 244.0
CSH3_k127_3160222_11 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000000000000000000000000009691 239.0
CSH3_k127_3160222_12 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000009246 228.0
CSH3_k127_3160222_13 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000000000000000000001511 211.0
CSH3_k127_3160222_14 LamG domain protein jellyroll fold domain protein - - - 0.000000000000000000000000000000000001376 159.0
CSH3_k127_3160222_15 - - - - 0.0000000000000000000000000000002291 128.0
CSH3_k127_3160222_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000000000000006128 113.0
CSH3_k127_3160222_17 RNA binding K09736 - - 0.0000000000000000000000003436 109.0
CSH3_k127_3160222_18 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000343 106.0
CSH3_k127_3160222_19 - - - - 0.0000000000000000000006154 98.0
CSH3_k127_3160222_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 550.0
CSH3_k127_3160222_20 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.000000000000000000001607 100.0
CSH3_k127_3160222_21 Polysaccharide deacetylase - - - 0.000000000000008983 84.0
CSH3_k127_3160222_22 COGs COG3293 Transposase and inactivated derivatives K07492 - - 0.0000000000000152 75.0
CSH3_k127_3160222_23 4Fe-4S binding domain - - - 0.00000000000004479 74.0
CSH3_k127_3160222_24 type I restriction-modification system K03427 - 2.1.1.72 0.0000000000004013 72.0
CSH3_k127_3160222_25 PFAM DNA polymerase, beta domain protein region K07076 - - 0.0000000009077 66.0
CSH3_k127_3160222_26 Protein of unknown function (DUF2283) - - - 0.00000001646 58.0
CSH3_k127_3160222_27 Polysaccharide pyruvyl transferase - - - 0.00000002126 66.0
CSH3_k127_3160222_28 Eco57I restriction-modification methylase - - - 0.0000000381 61.0
CSH3_k127_3160222_29 Type II restriction enzyme - - - 0.0000002297 59.0
CSH3_k127_3160222_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 513.0
CSH3_k127_3160222_30 Possibly the antitoxin component of a - - - 0.00001003 50.0
CSH3_k127_3160222_31 Polysaccharide deacetylase - - - 0.00001511 58.0
CSH3_k127_3160222_4 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 480.0
CSH3_k127_3160222_5 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 476.0
CSH3_k127_3160222_6 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 471.0
CSH3_k127_3160222_7 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 447.0
CSH3_k127_3160222_8 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 424.0
CSH3_k127_3160222_9 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 412.0
CSH3_k127_3217208_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1060.0
CSH3_k127_3217208_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 1.222e-226 709.0
CSH3_k127_3217208_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 445.0
CSH3_k127_3217208_3 Putative Fe-S cluster K11260 - - 0.0000000000000000000000000000000000000000000000000000003126 200.0
CSH3_k127_3217208_4 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000004204 185.0
CSH3_k127_3217208_5 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.00000000000000000000000000000000000000000000214 170.0
CSH3_k127_3217208_6 Molydopterin dinucleotide binding domain K00203 - 1.2.7.12 0.00000000000000000000000000009257 120.0
CSH3_k127_3217208_7 4Fe-4S dicluster domain - - - 0.00000000000000000000003259 101.0
CSH3_k127_3217208_8 Protein of unknown function (DUF1699) - - - 0.0000000000000000002638 94.0
CSH3_k127_3236441_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 537.0
CSH3_k127_3236441_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 446.0
CSH3_k127_3236441_10 Ras of Complex, Roc, domain of DAPkinase K06883 - - 0.00000000000000000000000000001933 124.0
CSH3_k127_3236441_11 toxin activity - - - 0.000000000000000000008206 101.0
CSH3_k127_3236441_12 - - - - 0.00000000000000000007842 97.0
CSH3_k127_3236441_13 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000007215 88.0
CSH3_k127_3236441_14 Leucine rich repeat - - - 0.000000000004677 80.0
CSH3_k127_3236441_15 - - - - 0.0003034 50.0
CSH3_k127_3236441_2 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 372.0
CSH3_k127_3236441_3 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000000000000001098 199.0
CSH3_k127_3236441_4 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000003018 186.0
CSH3_k127_3236441_5 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000001466 185.0
CSH3_k127_3236441_6 PFAM D-glucuronyl C5-epimerase domain protein - - - 0.000000000000000000000000000000000000002819 159.0
CSH3_k127_3236441_8 NUBPL iron-transfer P-loop NTPase K03609 - - 0.00000000000000000000000000000000002588 156.0
CSH3_k127_3236441_9 - - - - 0.000000000000000000000000000000286 130.0
CSH3_k127_3257624_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1153.0
CSH3_k127_3257624_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 8.52e-253 789.0
CSH3_k127_3257624_10 - - - - 0.000000000000000000000000001151 115.0
CSH3_k127_3257624_11 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.0000000000000000001623 91.0
CSH3_k127_3257624_12 Domain of unknown function (DUF1858) - - - 0.0000000000000000003835 89.0
CSH3_k127_3257624_13 PD-(D/E)XK nuclease superfamily - - - 0.000000009354 59.0
CSH3_k127_3257624_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 588.0
CSH3_k127_3257624_3 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 580.0
CSH3_k127_3257624_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 406.0
CSH3_k127_3257624_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 311.0
CSH3_k127_3257624_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
CSH3_k127_3257624_7 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000000000000000000000216 228.0
CSH3_k127_3257624_8 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000001009 238.0
CSH3_k127_3257624_9 metallopeptidase activity K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000009963 180.0
CSH3_k127_3353260_0 RNA ligase K07468 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 405.0
CSH3_k127_3353260_1 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 368.0
CSH3_k127_3353260_10 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000002184 107.0
CSH3_k127_3353260_11 Transposase - - - 0.000000000000000000006134 96.0
CSH3_k127_3353260_12 - - - - 0.0000000000002421 75.0
CSH3_k127_3353260_2 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
CSH3_k127_3353260_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
CSH3_k127_3353260_4 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005041 261.0
CSH3_k127_3353260_5 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
CSH3_k127_3353260_6 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000396 237.0
CSH3_k127_3353260_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000006416 209.0
CSH3_k127_3353260_8 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000000000001332 212.0
CSH3_k127_3353260_9 signal transduction protein with CBS domains - - - 0.000000000000000000000000000000000001499 144.0
CSH3_k127_3372838_0 PFAM CobN magnesium chelatase K02230 - 6.6.1.2 0.0 1867.0
CSH3_k127_3372838_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 467.0
CSH3_k127_3372838_2 - - - - 0.0000000000000000000000001148 113.0
CSH3_k127_3372838_3 PFAM nucleoside recognition domain protein - - - 0.00000000000009749 74.0
CSH3_k127_3372838_4 PQQ-like domain - - - 0.000000001582 59.0
CSH3_k127_3459065_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000004788 184.0
CSH3_k127_3459065_1 - - - - 0.00000000000000000108 89.0
CSH3_k127_3459065_3 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000001137 81.0
CSH3_k127_3463128_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.326e-304 945.0
CSH3_k127_3463128_1 Belongs to the carbamoyltransferase HypF family K04656 - - 2.636e-213 686.0
CSH3_k127_3463128_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.011e-194 614.0
CSH3_k127_3463128_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 548.0
CSH3_k127_3463128_4 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 481.0
CSH3_k127_3463128_5 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 432.0
CSH3_k127_3463128_6 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000003982 237.0
CSH3_k127_3463128_7 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000000000000000000000003272 203.0
CSH3_k127_3463128_8 hydrogenase maturation protease - - - 0.000000006735 63.0
CSH3_k127_3463128_9 - - - - 0.0000003065 55.0
CSH3_k127_3515675_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 401.0
CSH3_k127_3515675_1 Aerotolerance regulator N-terminal K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 388.0
CSH3_k127_3515675_2 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 293.0
CSH3_k127_3515675_3 Phenazine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 285.0
CSH3_k127_3515675_4 protein conserved in archaea K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000002672 233.0
CSH3_k127_3515675_6 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000000000000000000001147 200.0
CSH3_k127_3515675_7 - - - - 0.000000000000000000000001467 119.0
CSH3_k127_3515675_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000002432 68.0
CSH3_k127_3515675_9 - - - - 0.00002568 49.0
CSH3_k127_3571449_0 TIGRFAM CRISPR-associated RAMP protein - - - 0.0000000000000000000000000000000000000000003528 165.0
CSH3_k127_3571449_1 TIGRFAM CRISPR-associated RAMP protein - - - 0.0000000000000000000000000000000000000326 157.0
CSH3_k127_3571449_2 PFAM Transposase - - - 0.000000000000000000000000000001477 138.0
CSH3_k127_366693_0 metal-dependent membrane protease K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 419.0
CSH3_k127_366693_1 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 375.0
CSH3_k127_366693_10 transcriptional regulator - - - 0.0000000004742 66.0
CSH3_k127_366693_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001817 287.0
CSH3_k127_366693_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005126 261.0
CSH3_k127_366693_4 - K02573 - - 0.000000000000000000000000000000000000000000000000000000000000004909 225.0
CSH3_k127_366693_6 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000001285 125.0
CSH3_k127_366693_7 Alpha/beta hydrolase family - GO:0003674,GO:0003824,GO:0016787 - 0.000000000000002322 80.0
CSH3_k127_366693_8 Involved in initiation control of chromosome replication - - - 0.000000000000002742 78.0
CSH3_k127_366693_9 Protein of unknown function (DUF998) - - - 0.00000000003359 67.0
CSH3_k127_3688158_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 394.0
CSH3_k127_3688158_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 364.0
CSH3_k127_3688158_10 Domain of unknown function (DUF2341) - - - 0.0000000000000000005002 96.0
CSH3_k127_3688158_11 4Fe-4S single cluster domain - - - 0.000000000000000007413 94.0
CSH3_k127_3688158_12 4Fe-4S single cluster domain - - - 0.0000000000001343 81.0
CSH3_k127_3688158_14 - - - - 0.00000000007786 71.0
CSH3_k127_3688158_15 COG1404 Subtilisin-like serine proteases K14645 GO:0005575,GO:0005576 - 0.0000000001473 75.0
CSH3_k127_3688158_16 SEC-C motif - - - 0.000003853 59.0
CSH3_k127_3688158_17 nuclease - - - 0.000006578 61.0
CSH3_k127_3688158_2 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 357.0
CSH3_k127_3688158_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 338.0
CSH3_k127_3688158_4 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 291.0
CSH3_k127_3688158_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002774 231.0
CSH3_k127_3688158_7 - - - - 0.000000000000000000000000000000000000000000000000004433 183.0
CSH3_k127_3688158_8 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000009226 163.0
CSH3_k127_3742396_0 - K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 367.0
CSH3_k127_3742396_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 327.0
CSH3_k127_3742396_10 - - - - 0.000000000000000001751 96.0
CSH3_k127_3742396_11 - - - - 0.00000000000002347 80.0
CSH3_k127_3742396_12 - - - - 0.00000000000005085 72.0
CSH3_k127_3742396_13 - - - - 0.00002464 52.0
CSH3_k127_3742396_14 - - - - 0.0002764 51.0
CSH3_k127_3742396_2 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 303.0
CSH3_k127_3742396_3 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003838 280.0
CSH3_k127_3742396_5 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004489 242.0
CSH3_k127_3742396_6 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000001177 193.0
CSH3_k127_3742396_7 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000001463 190.0
CSH3_k127_3742396_8 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000000001852 119.0
CSH3_k127_3742396_9 - - - - 0.0000000000000000009377 93.0
CSH3_k127_3773053_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 591.0
CSH3_k127_3773053_1 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 565.0
CSH3_k127_3773053_10 Winged helix-turn-helix - - - 0.00000003801 58.0
CSH3_k127_3773053_11 - - - - 0.00008775 46.0
CSH3_k127_3773053_12 Involved in initiation control of chromosome replication K07484 - - 0.00009733 46.0
CSH3_k127_3773053_2 RimK domain protein ATP-grasp K05844,K15740 - 6.3.2.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002818 274.0
CSH3_k127_3773053_3 - - - - 0.000000000000000000000000000000000000000000008661 167.0
CSH3_k127_3773053_4 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000001974 152.0
CSH3_k127_3773053_5 - - - - 0.0000000000000000000000000000001083 140.0
CSH3_k127_3773053_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000142 121.0
CSH3_k127_3773053_7 Putative zinc ribbon domain - - - 0.00000000000000000008232 91.0
CSH3_k127_3773053_8 - - - - 0.000000000000057 74.0
CSH3_k127_3773053_9 - - - - 0.00000003189 58.0
CSH3_k127_3776183_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 344.0
CSH3_k127_3776183_1 SpoVT / AbrB like domain - - - 0.00000000004552 66.0
CSH3_k127_3776183_2 PIN domain K07064 - - 0.00000002482 61.0
CSH3_k127_3776183_3 Phage integrase family - - - 0.00003245 53.0
CSH3_k127_3802276_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 445.0
CSH3_k127_3802276_1 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 250.0
CSH3_k127_3802276_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
CSH3_k127_3802276_3 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000001352 254.0
CSH3_k127_3802276_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000003976 236.0
CSH3_k127_3802276_5 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000000000000000000000000249 181.0
CSH3_k127_3802276_6 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000001231 173.0
CSH3_k127_3802276_7 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000002775 163.0
CSH3_k127_3802276_8 S-layer protein - - - 0.000000000000000000000000000000003363 148.0
CSH3_k127_3802276_9 - - - - 0.0000000000000000000000001056 109.0
CSH3_k127_3803580_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.914e-218 705.0
CSH3_k127_3803580_1 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 546.0
CSH3_k127_3803580_10 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000003633 164.0
CSH3_k127_3803580_11 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000226 141.0
CSH3_k127_3803580_12 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000009833 120.0
CSH3_k127_3803580_13 Domain of unknown function (DUF1805) - - - 0.00000000000000000000000002057 110.0
CSH3_k127_3803580_14 Protein of unknown function (DUF2281) - - - 0.0000000000607 66.0
CSH3_k127_3803580_15 Uncharacterised protein family (UPF0175) - - - 0.00000003801 58.0
CSH3_k127_3803580_16 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0003504 44.0
CSH3_k127_3803580_2 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 450.0
CSH3_k127_3803580_3 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 395.0
CSH3_k127_3803580_4 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 340.0
CSH3_k127_3803580_5 Metallo-beta-lactamase superfamily K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 339.0
CSH3_k127_3803580_6 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 343.0
CSH3_k127_3803580_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000001512 254.0
CSH3_k127_3803580_8 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000001528 207.0
CSH3_k127_3803580_9 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000009201 198.0
CSH3_k127_3815097_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000008975 273.0
CSH3_k127_3815097_1 DDE superfamily endonuclease - - - 0.000000000000000000000002205 104.0
CSH3_k127_3815097_2 HEPN domain - - - 0.000006696 52.0
CSH3_k127_3815097_3 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00004342 47.0
CSH3_k127_3815097_4 Arrestin (or S-antigen), C-terminal domain K20910 GO:0000122,GO:0000302,GO:0002347,GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006355,GO:0006357,GO:0006606,GO:0006810,GO:0006886,GO:0006913,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0008104,GO:0008150,GO:0008544,GO:0009605,GO:0009607,GO:0009612,GO:0009628,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009913,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010941,GO:0010942,GO:0014070,GO:0015031,GO:0015833,GO:0017038,GO:0019219,GO:0019222,GO:0019899,GO:0023052,GO:0030154,GO:0030216,GO:0030234,GO:0030855,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031625,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032355,GO:0032501,GO:0032502,GO:0032570,GO:0033036,GO:0033365,GO:0033993,GO:0034284,GO:0034504,GO:0034613,GO:0042127,GO:0042221,GO:0042493,GO:0042542,GO:0042886,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043588,GO:0044092,GO:0044389,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045892,GO:0045934,GO:0046677,GO:0046907,GO:0048008,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051302,GO:0051592,GO:0051641,GO:0051649,GO:0051716,GO:0051782,GO:0060255,GO:0060429,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0071216,GO:0071228,GO:0071702,GO:0071705,GO:0072594,GO:0080090,GO:0098772,GO:1901654,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0002769 49.0
CSH3_k127_3820917_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000907 112.0
CSH3_k127_3820917_1 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000006566 112.0
CSH3_k127_3834762_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000002064 188.0
CSH3_k127_3834762_1 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.00000000007273 68.0
CSH3_k127_3869540_0 - - - - 0.0 1345.0
CSH3_k127_3869540_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.212e-298 921.0
CSH3_k127_3869540_10 Rhodanese Homology Domain - - - 0.0000000000000000000000004708 109.0
CSH3_k127_3869540_11 ATP synthase subunit C K02124 - - 0.0000000000000000000004112 98.0
CSH3_k127_3869540_12 Nucleotidyltransferase domain - - - 0.00000000000000000007672 94.0
CSH3_k127_3869540_13 HEPN domain - - - 0.00000000000000000008215 92.0
CSH3_k127_3869540_14 - - - - 0.00000000000000004906 91.0
CSH3_k127_3869540_15 transposition K07497 - - 0.000000000000002692 77.0
CSH3_k127_3869540_16 H subunit K02107 - - 0.00000000004607 67.0
CSH3_k127_3869540_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.65e-267 826.0
CSH3_k127_3869540_3 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 454.0
CSH3_k127_3869540_4 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 420.0
CSH3_k127_3869540_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01568,K04103 - 4.1.1.1,4.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 425.0
CSH3_k127_3869540_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 348.0
CSH3_k127_3869540_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 302.0
CSH3_k127_3869540_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000001968 158.0
CSH3_k127_3869540_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000003346 121.0
CSH3_k127_3917172_0 DEAD DEAH box helicase domain protein K03725 - - 6.498e-265 839.0
CSH3_k127_3917172_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 602.0
CSH3_k127_3917172_10 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000002674 204.0
CSH3_k127_3917172_11 - - - - 0.000000000000000000000000000000000000000000000000000009915 193.0
CSH3_k127_3917172_12 to GB L77117 SP Q58031 PID 1591324 percent identity - - - 0.00000000000000000000000000000000000000000000002413 173.0
CSH3_k127_3917172_13 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000001183 170.0
CSH3_k127_3917172_14 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000026 153.0
CSH3_k127_3917172_15 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.0000000000000000000000000002477 115.0
CSH3_k127_3917172_16 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000002016 113.0
CSH3_k127_3917172_17 PFAM Glutaredoxin K06191 - - 0.000000000000000000002013 96.0
CSH3_k127_3917172_18 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.000000000000000000005552 94.0
CSH3_k127_3917172_19 - - - - 0.00000000000000000002579 91.0
CSH3_k127_3917172_2 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 376.0
CSH3_k127_3917172_20 Domain of unknown function DUF302 - - - 0.0000000000000000000261 96.0
CSH3_k127_3917172_21 4Fe-4S binding domain K00171 - 1.2.7.1 0.00000000000000000009504 100.0
CSH3_k127_3917172_22 EamA-like transporter family - - - 0.00000006206 64.0
CSH3_k127_3917172_23 lysyltransferase activity K07027 - - 0.0000001143 63.0
CSH3_k127_3917172_24 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.000005466 49.0
CSH3_k127_3917172_25 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000532 49.0
CSH3_k127_3917172_26 Homeodomain-like domain - - - 0.0002798 43.0
CSH3_k127_3917172_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 338.0
CSH3_k127_3917172_4 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 325.0
CSH3_k127_3917172_5 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 299.0
CSH3_k127_3917172_6 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
CSH3_k127_3917172_7 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001733 268.0
CSH3_k127_3917172_8 PHP-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000001983 230.0
CSH3_k127_3917172_9 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000004241 222.0
CSH3_k127_3927725_0 COG0464 ATPases of the AAA class K13525 - - 1e-323 1005.0
CSH3_k127_3927725_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.95e-218 683.0
CSH3_k127_3927725_10 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 302.0
CSH3_k127_3927725_11 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
CSH3_k127_3927725_12 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000002331 256.0
CSH3_k127_3927725_13 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000001155 230.0
CSH3_k127_3927725_14 Conserved hypothetical protein 95 K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000003824 205.0
CSH3_k127_3927725_15 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000001873 176.0
CSH3_k127_3927725_16 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000000000000000000000008738 162.0
CSH3_k127_3927725_17 transposase K07492 - - 0.000000000000000000000000000000000000000002495 158.0
CSH3_k127_3927725_18 Flavodoxin - - - 0.000000000000000000000000002412 116.0
CSH3_k127_3927725_19 PFAM transposase, IS4 family protein K07492 - - 0.00000000000000000000000003323 108.0
CSH3_k127_3927725_2 Protein of unknown function (DUF460) K09150 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 541.0
CSH3_k127_3927725_20 PFAM PRC-barrel domain - - - 0.0000000000000000000004941 98.0
CSH3_k127_3927725_21 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000137 93.0
CSH3_k127_3927725_22 - - - - 0.0000000000000000001415 91.0
CSH3_k127_3927725_23 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000008327 85.0
CSH3_k127_3927725_24 Transposase - - - 0.00000000000001318 77.0
CSH3_k127_3927725_25 - - - - 0.0000000000512 65.0
CSH3_k127_3927725_26 - - - - 0.00000004132 61.0
CSH3_k127_3927725_27 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000005855 57.0
CSH3_k127_3927725_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 517.0
CSH3_k127_3927725_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 457.0
CSH3_k127_3927725_5 PFAM 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 395.0
CSH3_k127_3927725_6 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 388.0
CSH3_k127_3927725_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 312.0
CSH3_k127_3927725_8 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 310.0
CSH3_k127_3927725_9 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 310.0
CSH3_k127_3936020_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1182.0
CSH3_k127_3936020_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 400.0
CSH3_k127_3936020_10 regulator of chromosome condensation, RCC1 - - - 0.00000000000000001236 100.0
CSH3_k127_3936020_11 PFAM NHL repeat containing protein - - - 0.0000000000001176 78.0
CSH3_k127_3936020_12 - - - - 0.000001563 53.0
CSH3_k127_3936020_2 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 346.0
CSH3_k127_3936020_3 S-layer protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 319.0
CSH3_k127_3936020_4 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
CSH3_k127_3936020_5 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004394 247.0
CSH3_k127_3936020_6 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000001423 166.0
CSH3_k127_3936020_7 S-layer protein - - - 0.00000000000000000000000000004293 138.0
CSH3_k127_3936020_8 PFAM regulatory protein, ArsR K21903 - - 0.0000000000000000000000006366 108.0
CSH3_k127_3936020_9 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.000000000000000000000002946 106.0
CSH3_k127_3942398_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 292.0
CSH3_k127_3942398_1 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 288.0
CSH3_k127_3942398_3 Transposase DDE domain K07492 - - 0.00000000000006958 71.0
CSH3_k127_3942398_4 - - - - 0.00000000506 63.0
CSH3_k127_3942398_5 - - - - 0.00009894 49.0
CSH3_k127_3979356_0 helicase superfamily c-terminal domain K07012 - - 0.0000000000000000000000000000000000001016 146.0
CSH3_k127_3979356_1 CRISPR-associated protein Cas4 K07464 GO:0000738,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0030145,GO:0034641,GO:0034655,GO:0035312,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045145,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.12.1 0.0000000000000000000000000000000001573 135.0
CSH3_k127_3979356_2 - - - - 0.00000000000000004439 86.0
CSH3_k127_3979356_3 Periplasmic copper-binding protein (NosD) - - - 0.0000000001175 72.0
CSH3_k127_3979356_4 - - - - 0.00000009584 54.0
CSH3_k127_3979356_5 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00003883 53.0
CSH3_k127_3979356_6 nuclease activity - - - 0.000108 48.0
CSH3_k127_3982699_0 small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 411.0
CSH3_k127_3982699_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001442 269.0
CSH3_k127_3982699_2 Inter-alpha-trypsin inhibitor heavy chain - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008908 272.0
CSH3_k127_3982699_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000132 198.0
CSH3_k127_3982699_4 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000000000638 124.0
CSH3_k127_3982699_5 Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000005564 116.0
CSH3_k127_3982699_6 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.00000000005058 66.0
CSH3_k127_3983734_0 Involved in cell shape control K22222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 460.0
CSH3_k127_3983734_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 417.0
CSH3_k127_3983734_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000652 189.0
CSH3_k127_3983734_3 Type III K01153 - 3.1.21.3 0.00000000000000003361 83.0
CSH3_k127_3983734_4 4 iron, 4 sulfur cluster binding K11260 - - 0.00000002479 57.0
CSH3_k127_3983734_5 Domain of unknown function DUF11 - - - 0.0008533 51.0
CSH3_k127_4060345_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 521.0
CSH3_k127_4060345_1 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 378.0
CSH3_k127_4060345_10 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000001242 235.0
CSH3_k127_4060345_11 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000003419 239.0
CSH3_k127_4060345_12 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000005404 231.0
CSH3_k127_4060345_13 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000007722 200.0
CSH3_k127_4060345_14 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000003658 159.0
CSH3_k127_4060345_15 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000001438 153.0
CSH3_k127_4060345_16 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000001373 139.0
CSH3_k127_4060345_17 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000009146 121.0
CSH3_k127_4060345_18 transposition, DNA-mediated - - - 0.0000000000000000000000000014 116.0
CSH3_k127_4060345_19 transposase K07492 - - 0.0000000000000000000003797 97.0
CSH3_k127_4060345_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 341.0
CSH3_k127_4060345_3 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
CSH3_k127_4060345_4 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 315.0
CSH3_k127_4060345_5 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 319.0
CSH3_k127_4060345_6 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 292.0
CSH3_k127_4060345_7 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 288.0
CSH3_k127_4060345_8 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000001701 246.0
CSH3_k127_4060345_9 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000003247 244.0
CSH3_k127_4074735_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 332.0
CSH3_k127_4074735_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005525 236.0
CSH3_k127_4074735_2 COG0500 SAM-dependent methyltransferases K17462 - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
CSH3_k127_4074735_3 Restriction modification system DNA specificity K01154 - 3.1.21.3 0.000000000000000000000000000000005766 132.0
CSH3_k127_4074735_4 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000007024 91.0
CSH3_k127_4074735_5 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000001833 75.0
CSH3_k127_4074735_6 Type I restriction modification DNA specificity domain protein - - - 0.0000001558 56.0
CSH3_k127_4076070_0 PFAM ABC transporter K00400 - - 3.679e-245 766.0
CSH3_k127_4076070_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 601.0
CSH3_k127_4076070_10 PFAM Glutaredoxin K06191 - - 0.0000000000000000000008901 98.0
CSH3_k127_4076070_11 Winged helix-turn helix - - - 0.0000000007173 67.0
CSH3_k127_4076070_12 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000002929 58.0
CSH3_k127_4076070_2 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 493.0
CSH3_k127_4076070_3 methanogenesis marker protein 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 393.0
CSH3_k127_4076070_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 334.0
CSH3_k127_4076070_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 299.0
CSH3_k127_4076070_6 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000001915 206.0
CSH3_k127_4076070_7 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000002447 172.0
CSH3_k127_4076070_8 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000001427 148.0
CSH3_k127_4076070_9 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000002083 136.0
CSH3_k127_4083498_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 300.0
CSH3_k127_4083498_1 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 289.0
CSH3_k127_4083498_2 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003984 255.0
CSH3_k127_4083498_3 extracellular matrix structural constituent - - - 0.0000000000000000000002944 110.0
CSH3_k127_4083498_4 FtsX-like permease family K09808 - - 0.00000000000000006204 93.0
CSH3_k127_4094275_0 Transcriptional regulator, AbiEi antitoxin - - - 0.00000000000000000000000000000000002346 145.0
CSH3_k127_4094275_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.000000000000000000000000000003843 129.0
CSH3_k127_4094275_2 Helix-turn-helix of DDE superfamily endonuclease - - - 0.000000000006455 67.0
CSH3_k127_4094275_3 DDE superfamily endonuclease - - - 0.00000006804 55.0
CSH3_k127_4094275_4 PFAM transposase, IS4 family protein - - - 0.00000189 50.0
CSH3_k127_4094349_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.029e-295 916.0
CSH3_k127_4094349_1 Type III K01153 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 390.0
CSH3_k127_4094349_2 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 355.0
CSH3_k127_4094349_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 338.0
CSH3_k127_4094349_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000003402 169.0
CSH3_k127_4094349_5 Transcriptional regulator K11924 - - 0.0000000000000000000000000002561 116.0
CSH3_k127_4094349_6 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000005173 75.0
CSH3_k127_4112905_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 284.0
CSH3_k127_4112905_1 ATPase, AAA superfamily K06921 - - 0.000000000000000000000000000000000000000000000000000000000004559 221.0
CSH3_k127_4112905_2 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000005467 190.0
CSH3_k127_4112905_3 PFAM Transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000005723 169.0
CSH3_k127_4112905_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0001106 54.0
CSH3_k127_4115766_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.67e-226 714.0
CSH3_k127_4115766_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 565.0
CSH3_k127_4115766_10 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000002284 235.0
CSH3_k127_4115766_11 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000004715 212.0
CSH3_k127_4115766_12 Protein of unknown function (DUF1699) - - - 0.0000000000000000000000000000000000000000000000000001294 188.0
CSH3_k127_4115766_13 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000003948 192.0
CSH3_k127_4115766_14 Binding-protein-dependent transport system inner membrane component K02050,K15552,K15554 - - 0.0000000000000000000000000000000000000000000002145 177.0
CSH3_k127_4115766_15 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000005067 98.0
CSH3_k127_4115766_2 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 525.0
CSH3_k127_4115766_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 491.0
CSH3_k127_4115766_4 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 478.0
CSH3_k127_4115766_5 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 424.0
CSH3_k127_4115766_6 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 317.0
CSH3_k127_4115766_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 310.0
CSH3_k127_4115766_8 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007564 271.0
CSH3_k127_4115766_9 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000000000000000000002197 236.0
CSH3_k127_4130581_0 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 591.0
CSH3_k127_4130581_1 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 394.0
CSH3_k127_4130581_10 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.00000005923 55.0
CSH3_k127_4130581_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 376.0
CSH3_k127_4130581_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 362.0
CSH3_k127_4130581_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 334.0
CSH3_k127_4130581_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002554 284.0
CSH3_k127_4130581_6 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000003379 196.0
CSH3_k127_4130581_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000002894 166.0
CSH3_k127_4130581_8 - - - - 0.0000000000000000000000000000000000000007788 162.0
CSH3_k127_4130581_9 - - - - 0.00000000000000000000000002477 110.0
CSH3_k127_4145113_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 331.0
CSH3_k127_4145113_1 - K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 314.0
CSH3_k127_4145113_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000008061 226.0
CSH3_k127_4145113_3 PFAM methyltransferase small K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000005693 196.0
CSH3_k127_4145113_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000002246 124.0
CSH3_k127_4145113_5 Protein of unknown function (DUF1699) - - - 0.000000000000000000000004926 104.0
CSH3_k127_4145113_6 Methionine biosynthesis protein MetW - - - 0.000000000004838 70.0
CSH3_k127_4145113_7 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 0.00009243 46.0
CSH3_k127_4145813_0 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000004338 206.0
CSH3_k127_4145813_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000009558 96.0
CSH3_k127_4145813_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000001614 94.0
CSH3_k127_4145813_3 PFAM Glycosyl transferases group 1 - - - 0.00000002066 61.0
CSH3_k127_4145813_4 Major Facilitator Superfamily K08156,K19577 - - 0.0004488 47.0
CSH3_k127_4149778_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.829e-206 648.0
CSH3_k127_4149778_1 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 534.0
CSH3_k127_4149778_10 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001421 246.0
CSH3_k127_4149778_11 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000005366 234.0
CSH3_k127_4149778_12 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000001409 215.0
CSH3_k127_4149778_13 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000003682 210.0
CSH3_k127_4149778_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000006727 207.0
CSH3_k127_4149778_15 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000001214 162.0
CSH3_k127_4149778_16 transposase K07492 - - 0.000000000000000000000000000000000000000002592 162.0
CSH3_k127_4149778_17 - - - - 0.0000000000000000000000000000000008978 136.0
CSH3_k127_4149778_18 - - - - 0.0000000000000000000001918 98.0
CSH3_k127_4149778_2 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 507.0
CSH3_k127_4149778_20 - - - - 0.000000002387 62.0
CSH3_k127_4149778_21 cAMP biosynthetic process - - - 0.0000007783 59.0
CSH3_k127_4149778_3 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 461.0
CSH3_k127_4149778_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 432.0
CSH3_k127_4149778_5 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 346.0
CSH3_k127_4149778_6 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 333.0
CSH3_k127_4149778_7 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 300.0
CSH3_k127_4149778_8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 285.0
CSH3_k127_4149778_9 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 286.0
CSH3_k127_415120_0 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0 1129.0
CSH3_k127_415120_1 HsdM N-terminal domain K03427 - 2.1.1.72 4.296e-254 789.0
CSH3_k127_415120_2 restriction K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 344.0
CSH3_k127_415120_3 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005851 273.0
CSH3_k127_4157137_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 6.285e-202 642.0
CSH3_k127_4157137_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 540.0
CSH3_k127_4157137_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 291.0
CSH3_k127_4157137_3 - - - - 0.000000000000000000000000000000000005442 144.0
CSH3_k127_4157137_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000001266 61.0
CSH3_k127_4176028_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 4.996e-269 845.0
CSH3_k127_4176028_1 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000001301 239.0
CSH3_k127_4176028_2 - - - - 0.00000000000000000000000000000000000001356 153.0
CSH3_k127_4176028_3 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000002026 123.0
CSH3_k127_4176028_4 DDE superfamily endonuclease K07494,K07499 - - 0.00000005841 56.0
CSH3_k127_418672_0 4Fe-4S dicluster domain - - - 1.926e-265 831.0
CSH3_k127_418672_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 9.133e-261 817.0
CSH3_k127_418672_10 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 312.0
CSH3_k127_418672_11 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 303.0
CSH3_k127_418672_12 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 298.0
CSH3_k127_418672_13 PFAM WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000004581 246.0
CSH3_k127_418672_14 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000001083 185.0
CSH3_k127_418672_15 binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000000003723 147.0
CSH3_k127_418672_16 DDE superfamily endonuclease - - - 0.0000000000000000000000001384 108.0
CSH3_k127_418672_17 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000001974 106.0
CSH3_k127_418672_18 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000000000002972 99.0
CSH3_k127_418672_19 PspC domain - - - 0.0000000000000000001182 94.0
CSH3_k127_418672_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 563.0
CSH3_k127_418672_20 - - - - 0.0000000000000000002962 91.0
CSH3_k127_418672_21 protein conserved in archaea K09723 - - 0.000000000000000001945 94.0
CSH3_k127_418672_22 DDE superfamily endonuclease K07495 - - 0.000000000000002728 78.0
CSH3_k127_418672_23 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000001184 66.0
CSH3_k127_418672_24 transcriptional regulators - - - 0.00000000007782 74.0
CSH3_k127_418672_25 PAS fold - - - 0.000005028 58.0
CSH3_k127_418672_26 WD40-like Beta Propeller - - - 0.00001839 57.0
CSH3_k127_418672_27 PFAM Pentapeptide repeats (8 copies) - - - 0.00001868 55.0
CSH3_k127_418672_28 Phage integrase family - - - 0.0001422 45.0
CSH3_k127_418672_29 - - - - 0.0001466 52.0
CSH3_k127_418672_3 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 559.0
CSH3_k127_418672_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 406.0
CSH3_k127_418672_5 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 404.0
CSH3_k127_418672_6 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 391.0
CSH3_k127_418672_7 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 357.0
CSH3_k127_418672_8 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 362.0
CSH3_k127_418672_9 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 340.0
CSH3_k127_4212258_0 PD-(D/E)XK nuclease superfamily K03657 - 3.6.4.12 0.0 1165.0
CSH3_k127_4212258_1 DNA methylase - - - 1.298e-277 885.0
CSH3_k127_4212258_2 Type III restriction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 568.0
CSH3_k127_4212258_3 Type III restriction enzyme, res subunit - - - 0.00000000000000000000003776 115.0
CSH3_k127_4219255_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 517.0
CSH3_k127_4219255_1 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 453.0
CSH3_k127_4219255_10 transcriptional - - - 0.000000000000000000000000000007873 120.0
CSH3_k127_4219255_11 - - - - 0.0000000000000000134 86.0
CSH3_k127_4219255_12 - - - - 0.000000001756 60.0
CSH3_k127_4219255_13 - - - - 0.00008955 49.0
CSH3_k127_4219255_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 332.0
CSH3_k127_4219255_3 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001281 244.0
CSH3_k127_4219255_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
CSH3_k127_4219255_5 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000001634 225.0
CSH3_k127_4219255_6 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000009006 190.0
CSH3_k127_4219255_7 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000003936 187.0
CSH3_k127_4219255_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000002212 187.0
CSH3_k127_4219255_9 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000001047 162.0
CSH3_k127_422093_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 527.0
CSH3_k127_422093_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 349.0
CSH3_k127_422093_2 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 301.0
CSH3_k127_422093_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000001946 122.0
CSH3_k127_422093_4 Flavodoxin - - - 0.0004679 46.0
CSH3_k127_42286_0 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 414.0
CSH3_k127_42286_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 359.0
CSH3_k127_42286_10 - - - - 0.00000000000000000000000000001788 119.0
CSH3_k127_42286_11 Sulfurtransferase TusA K04085 - - 0.000000000000000000227 89.0
CSH3_k127_42286_12 DsrE/DsrF-like family K07236 - - 0.0000000000007326 72.0
CSH3_k127_42286_13 E-Z type HEAT repeats - - - 0.00000000004572 76.0
CSH3_k127_42286_14 PFAM MULE transposase, conserved domain - - - 0.0000000004834 72.0
CSH3_k127_42286_15 - - - - 0.0000002443 58.0
CSH3_k127_42286_16 - - - - 0.00004266 50.0
CSH3_k127_42286_17 Winged helix-turn helix - - - 0.0002377 46.0
CSH3_k127_42286_2 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 339.0
CSH3_k127_42286_3 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
CSH3_k127_42286_4 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 310.0
CSH3_k127_42286_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 290.0
CSH3_k127_42286_6 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003598 267.0
CSH3_k127_42286_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001963 225.0
CSH3_k127_42286_8 flagella protein K07327,K07328 - - 0.0000000000000000000000000000000000000000000002577 181.0
CSH3_k127_42286_9 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000153 134.0
CSH3_k127_4343094_0 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000001222 250.0
CSH3_k127_4343094_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000002228 226.0
CSH3_k127_4343094_2 Matrixin - - - 0.0000000000000000000000000000002026 133.0
CSH3_k127_4343094_3 40-residue YVTN family beta-propeller - - - 0.00000000004235 78.0
CSH3_k127_4343094_4 Cna B domain protein - - - 0.0008211 53.0
CSH3_k127_4349234_0 Bacterial regulatory protein, Fis family K02667 - - 6.082e-207 652.0
CSH3_k127_4349234_1 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 533.0
CSH3_k127_4349234_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 345.0
CSH3_k127_4349234_3 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000003547 137.0
CSH3_k127_4349234_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000004134 100.0
CSH3_k127_4368773_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 370.0
CSH3_k127_4368773_1 S4 RNA-binding domain K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000104 217.0
CSH3_k127_4368773_2 - - - - 0.00000000000000000000000000000005457 132.0
CSH3_k127_4368773_3 Transposase DDE domain K07492 - - 0.00000000000000000000007076 97.0
CSH3_k127_4368773_4 Protein of unknown function (DUF3344) - - - 0.0000000000007282 81.0
CSH3_k127_4368773_5 - - - - 0.00000000002812 64.0
CSH3_k127_4395109_0 Domain of unknown function (DUF4062) - - - 6.885e-243 791.0
CSH3_k127_4395109_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 492.0
CSH3_k127_4401033_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 392.0
CSH3_k127_4401033_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000029 265.0
CSH3_k127_4401033_2 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000001545 243.0
CSH3_k127_4401033_3 Involved in initiation control of chromosome replication - - - 0.0000000000000000000000000000000000000000000000000000000000000001518 232.0
CSH3_k127_4401033_4 Restriction endonuclease - - - 0.0000000001114 63.0
CSH3_k127_4401033_5 PFAM plasmid stabilization system - - - 0.00001983 49.0
CSH3_k127_4403516_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 357.0
CSH3_k127_4403516_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 332.0
CSH3_k127_4403516_10 - K06864 - - 0.000000000000006216 79.0
CSH3_k127_4403516_2 SMART Elongator protein 3 MiaB NifB K06935,K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 334.0
CSH3_k127_4403516_3 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
CSH3_k127_4403516_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000004155 204.0
CSH3_k127_4403516_5 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000008871 198.0
CSH3_k127_4403516_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000001377 184.0
CSH3_k127_4403516_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000005805 121.0
CSH3_k127_4403516_8 Protein of unknown function (DUF3795) - - - 0.000000000000000000001554 98.0
CSH3_k127_4403516_9 - - - - 0.0000000000000001358 83.0
CSH3_k127_4408789_0 Double zinc ribbon - - - 0.00000000000000000000000000003572 123.0
CSH3_k127_4408789_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000003567 99.0
CSH3_k127_4408789_2 Transposase - - - 0.00000000000000007621 83.0
CSH3_k127_4419355_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 533.0
CSH3_k127_4419355_1 Protein of unknown function (DUF3344) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 441.0
CSH3_k127_4419355_10 - - - - 0.0000000000000000000000000000000000000000000000000007232 194.0
CSH3_k127_4419355_11 von Willebrand factor, type A - - - 0.00000000000000000000000000000000006273 140.0
CSH3_k127_4419355_12 - - - - 0.000000000000000000000000000000001553 136.0
CSH3_k127_4419355_13 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000001906 105.0
CSH3_k127_4419355_14 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000003056 49.0
CSH3_k127_4419355_15 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000143 51.0
CSH3_k127_4419355_16 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis - - - 0.00003995 50.0
CSH3_k127_4419355_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 377.0
CSH3_k127_4419355_3 ABC-type Cobalt transport system, permease K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 325.0
CSH3_k127_4419355_4 Protein of unknown function (DUF3344) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 299.0
CSH3_k127_4419355_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003191 286.0
CSH3_k127_4419355_6 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005285 290.0
CSH3_k127_4419355_7 Transcriptional regulator K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001211 280.0
CSH3_k127_4419355_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001135 254.0
CSH3_k127_4419355_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001157 255.0
CSH3_k127_4446977_0 AAA family ATPase, CDC48 subfamily K13525 - - 2.789e-314 977.0
CSH3_k127_4446977_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 447.0
CSH3_k127_4446977_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 389.0
CSH3_k127_4446977_3 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 364.0
CSH3_k127_4446977_4 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000001351 226.0
CSH3_k127_4446977_5 - - - - 0.000000000000000000000000000000000000000000000000000000004698 202.0
CSH3_k127_4446977_6 Protein of unknown function DUF84 - - - 0.000000000000000000000000000000000000001233 154.0
CSH3_k127_4446977_7 - - - - 0.0000000000000000000000000002049 116.0
CSH3_k127_4446977_8 Chorismate mutase type II K04782 - 4.2.99.21 0.000000001665 59.0
CSH3_k127_4446977_9 Hsp20/alpha crystallin family K13993 - - 0.000000002195 64.0
CSH3_k127_4448127_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 349.0
CSH3_k127_4448127_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008431 291.0
CSH3_k127_4448127_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001502 253.0
CSH3_k127_4448127_3 Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002796 225.0
CSH3_k127_4448127_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
CSH3_k127_4448127_5 Aspartyl protease - - - 0.000001604 54.0
CSH3_k127_4448127_6 Phospholipid methyltransferase - - - 0.0000017 50.0
CSH3_k127_4492367_0 Subtilase family K13277 - - 0.000000000000000000000000000000000000000000000000000000000000000000005567 241.0
CSH3_k127_4492367_1 - - - - 0.00000001718 57.0
CSH3_k127_4492367_2 Domain of unknown function (DUF4367) - - - 0.0000001665 58.0
CSH3_k127_4525139_0 Domain of unknown function (DUF2341) - - - 0.0000000000000000000000000000003668 137.0
CSH3_k127_4525139_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000003387 106.0
CSH3_k127_4525139_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162 - 1.2.4.1 0.000000000000000193 92.0
CSH3_k127_4525139_3 sulfur carrier activity K04085 - - 0.0000000002008 64.0
CSH3_k127_4545307_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 523.0
CSH3_k127_4545307_1 - K07341 - - 0.00000005275 54.0
CSH3_k127_4552039_0 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000000002305 184.0
CSH3_k127_4552039_1 Pfam:DUF1628 - - - 0.000000000000000000000000003221 116.0
CSH3_k127_4552039_2 Family of unknown function (DUF5371) - - - 0.000000001953 63.0
CSH3_k127_4552039_3 Archaeal Type IV pilin, N-terminal - - - 0.00002472 53.0
CSH3_k127_4552955_0 nucleic acid-binding protein contains PIN domain K07066 - - 0.000000000000000000000000000000000209 139.0
CSH3_k127_4552955_1 Protein of unknown function (DUF4064) - - - 0.00000000000000000000000001573 113.0
CSH3_k127_4552955_2 Protein of unknown function (DUF2442) - - - 0.00000000000000000000007935 99.0
CSH3_k127_4552955_3 Domain of unknown function (DUF4160) - - - 0.000000000000000000002144 95.0
CSH3_k127_4552955_4 Uncharacterised protein family (UPF0175) - - - 0.00000000000000003238 84.0
CSH3_k127_4552955_5 Domain of unknown function (DUF4352) - - - 0.000000000004872 75.0
CSH3_k127_4552955_6 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000007517 48.0
CSH3_k127_4552955_7 - - - - 0.00005419 51.0
CSH3_k127_4600501_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 605.0
CSH3_k127_4600501_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 498.0
CSH3_k127_4600501_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 451.0
CSH3_k127_4600501_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 401.0
CSH3_k127_4600501_4 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000007353 167.0
CSH3_k127_4600501_5 Uncharacterized metal-binding protein (DUF2227) - - - 0.0000000000000003995 83.0
CSH3_k127_4600501_6 PFAM Rhomboid family protein - - - 0.0000000000000407 81.0
CSH3_k127_4635874_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 1.62e-224 706.0
CSH3_k127_4635874_1 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 624.0
CSH3_k127_4635874_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000001577 217.0
CSH3_k127_4635874_11 Glycosyltransferase like family 2 K13002 - - 0.000000000000000000000000000000000000000000000000000000000002377 218.0
CSH3_k127_4635874_12 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000000000006986 203.0
CSH3_k127_4635874_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000001523 190.0
CSH3_k127_4635874_14 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000002212 148.0
CSH3_k127_4635874_15 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000000002467 138.0
CSH3_k127_4635874_16 - K00960 - 2.7.7.6 0.0000000000000000000000001221 106.0
CSH3_k127_4635874_17 - K00960 - 2.7.7.6 0.0000000000000000000000005965 104.0
CSH3_k127_4635874_18 PFAM YHS domain - - - 0.0000000000000001153 81.0
CSH3_k127_4635874_19 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000001115 77.0
CSH3_k127_4635874_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 479.0
CSH3_k127_4635874_20 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00000003595 56.0
CSH3_k127_4635874_21 Methionine biosynthesis protein MetW - - - 0.00003797 55.0
CSH3_k127_4635874_3 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 447.0
CSH3_k127_4635874_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
CSH3_k127_4635874_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
CSH3_k127_4635874_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 291.0
CSH3_k127_4635874_7 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001683 284.0
CSH3_k127_4635874_8 pfam ammecr1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000001664 223.0
CSH3_k127_4635874_9 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000001407 216.0
CSH3_k127_465294_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 542.0
CSH3_k127_465294_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 525.0
CSH3_k127_465294_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 323.0
CSH3_k127_465294_3 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.00000000000000000000000000000000000000000000000000007972 192.0
CSH3_k127_465294_4 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000000000000000000000000000000002587 171.0
CSH3_k127_465294_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000003228 136.0
CSH3_k127_465294_6 Family of unknown function (DUF5350) - - - 0.0000000000001565 72.0
CSH3_k127_465294_7 DDE superfamily endonuclease - - - 0.0000005215 51.0
CSH3_k127_4679791_0 DEAD DEAH box helicase domain protein K10896 - - 2.052e-277 871.0
CSH3_k127_4679791_1 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 8.799e-197 623.0
CSH3_k127_4679791_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 606.0
CSH3_k127_4679791_3 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 531.0
CSH3_k127_4679791_4 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02588,K21610 - 1.18.6.1,6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 327.0
CSH3_k127_4679791_5 - K02450 - - 0.0000000000000000000000000000001945 137.0
CSH3_k127_4679791_6 Phospholipid methyltransferase - - - 0.000000000000000001552 93.0
CSH3_k127_4679791_7 - - - - 0.000001405 55.0
CSH3_k127_4710886_0 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 426.0
CSH3_k127_4710886_1 DDE superfamily endonuclease - - - 0.000000000000003585 81.0
CSH3_k127_4710886_2 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.000001536 61.0
CSH3_k127_4715410_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 519.0
CSH3_k127_4715410_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 396.0
CSH3_k127_4715410_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 325.0
CSH3_k127_4715410_3 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000663 220.0
CSH3_k127_4715410_4 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000000000000000000000388 153.0
CSH3_k127_4717693_0 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 325.0
CSH3_k127_4717693_1 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000384 278.0
CSH3_k127_4717693_2 PFAM metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000004556 218.0
CSH3_k127_4717693_3 Protein of unknown function (DUF2551) - - - 0.00000000000000000000005627 102.0
CSH3_k127_4717693_4 - - - - 0.0000000000001051 76.0
CSH3_k127_4717693_5 - - - - 0.000000000001982 75.0
CSH3_k127_4717693_6 - - - - 0.00000000000468 70.0
CSH3_k127_4717693_7 - - - - 0.00000000004248 67.0
CSH3_k127_4717693_8 - - - - 0.0000000001094 70.0
CSH3_k127_4717693_9 - - - - 0.00000002423 58.0
CSH3_k127_4720653_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 532.0
CSH3_k127_4720653_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 518.0
CSH3_k127_4720653_10 Leiomodin-3 K22030 GO:0003008,GO:0003012,GO:0003674,GO:0003779,GO:0003785,GO:0005488,GO:0005515,GO:0005523,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005865,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007517,GO:0007519,GO:0008064,GO:0008092,GO:0008150,GO:0009653,GO:0009888,GO:0009987,GO:0010638,GO:0010720,GO:0010830,GO:0010831,GO:0010927,GO:0014706,GO:0014866,GO:0014902,GO:0014904,GO:0015629,GO:0016043,GO:0016202,GO:0022607,GO:0030016,GO:0030017,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030240,GO:0030832,GO:0030833,GO:0030838,GO:0031032,GO:0031334,GO:0031430,GO:0031672,GO:0032271,GO:0032273,GO:0032501,GO:0032502,GO:0032535,GO:0032956,GO:0032970,GO:0032989,GO:0033043,GO:0036379,GO:0042692,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043292,GO:0044085,GO:0044087,GO:0044089,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045010,GO:0045595,GO:0045597,GO:0045844,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048634,GO:0048636,GO:0048641,GO:0048643,GO:0048646,GO:0048731,GO:0048741,GO:0048742,GO:0048743,GO:0048747,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051239,GO:0051240,GO:0051493,GO:0051495,GO:0055001,GO:0055002,GO:0060284,GO:0060537,GO:0060538,GO:0061061,GO:0065007,GO:0065008,GO:0070925,GO:0071840,GO:0090066,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0110053,GO:1901861,GO:1901863,GO:1902903,GO:1902905,GO:2000026 - 0.0004308 46.0
CSH3_k127_4720653_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 518.0
CSH3_k127_4720653_3 Protein of unknown function (DUF1464) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004988 287.0
CSH3_k127_4720653_4 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000176 269.0
CSH3_k127_4720653_5 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000992 252.0
CSH3_k127_4720653_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000001137 190.0
CSH3_k127_4720653_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000046 187.0
CSH3_k127_4720653_8 PFAM PUA domain containing protein K07398 - - 0.0000000000000000000000000000000000000000000000002601 181.0
CSH3_k127_4720653_9 Urm1 (Ubiquitin related modifier) K03636 - - 0.00000000000000000008588 92.0
CSH3_k127_4724859_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 3.943e-315 977.0
CSH3_k127_4724859_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 2.567e-231 728.0
CSH3_k127_4724859_10 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000002991 248.0
CSH3_k127_4724859_11 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000001583 230.0
CSH3_k127_4724859_12 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000004056 216.0
CSH3_k127_4724859_13 competence protein COMEC K02238 - - 0.0000000000000000000000000000000000000000000000000000006655 215.0
CSH3_k127_4724859_14 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000007677 141.0
CSH3_k127_4724859_15 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000006244 135.0
CSH3_k127_4724859_16 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000004174 92.0
CSH3_k127_4724859_17 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000007093 69.0
CSH3_k127_4724859_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000008966 61.0
CSH3_k127_4724859_19 - - - - 0.000000008325 66.0
CSH3_k127_4724859_2 Histidine kinase K07646 - 2.7.13.3 2.161e-201 646.0
CSH3_k127_4724859_3 UbiD family K03182 - 4.1.1.98 3.979e-199 630.0
CSH3_k127_4724859_4 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 607.0
CSH3_k127_4724859_5 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 441.0
CSH3_k127_4724859_6 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 407.0
CSH3_k127_4724859_7 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 318.0
CSH3_k127_4724859_8 Conserved hypothetical ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001386 270.0
CSH3_k127_4724859_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003882 255.0
CSH3_k127_4732935_0 Tn3 transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 481.0
CSH3_k127_4732935_1 Transposase and inactivated derivatives, TnpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 361.0
CSH3_k127_4732935_2 - - - - 0.000000000000000000000000000000003465 132.0
CSH3_k127_4732935_3 Domain of unknown function (DUF4158) - - - 0.0000000000000000000000001282 111.0
CSH3_k127_4732935_4 Domain of unknown function (DUF4158) - - - 0.000000000000000000002728 93.0
CSH3_k127_4732935_5 Psort location Cytoplasmic, score - - - 0.00000002209 60.0
CSH3_k127_4732935_6 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000001464 51.0
CSH3_k127_4756931_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 1.123e-254 796.0
CSH3_k127_4756931_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.627e-230 732.0
CSH3_k127_4756931_10 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002609 254.0
CSH3_k127_4756931_11 COG1226 Kef-type K transport systems - - - 0.0000000000000000000000000000000000000000000000000000000003306 209.0
CSH3_k127_4756931_12 Methyl-coenzyme M reductase operon protein D K03422 - - 0.000000000000000000000000000000000000000195 155.0
CSH3_k127_4756931_13 Protein of unknown function (DUF356) K09727 - - 0.00000000000000000000000000000009912 128.0
CSH3_k127_4756931_14 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.0000000000000000000000000000008696 130.0
CSH3_k127_4756931_15 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000007995 88.0
CSH3_k127_4756931_16 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.000000003088 64.0
CSH3_k127_4756931_17 beta-lactamase activity K07126 - - 0.0000004489 54.0
CSH3_k127_4756931_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 592.0
CSH3_k127_4756931_3 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 560.0
CSH3_k127_4756931_4 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 548.0
CSH3_k127_4756931_5 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 505.0
CSH3_k127_4756931_6 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 407.0
CSH3_k127_4756931_7 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 362.0
CSH3_k127_4756931_8 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 317.0
CSH3_k127_4756931_9 PFAM TrkA-N domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 307.0
CSH3_k127_4764924_0 Type III restriction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 308.0
CSH3_k127_4764924_1 Proline racemase K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000007273 229.0
CSH3_k127_4764924_2 Restriction endonuclease K07448 - - 0.000002905 53.0
CSH3_k127_4772008_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000005409 229.0
CSH3_k127_4772008_1 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000001362 183.0
CSH3_k127_4772008_2 Flavodoxin - - - 0.000000000000000000000000000000000000000000007397 166.0
CSH3_k127_4772008_3 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000006354 110.0
CSH3_k127_4772008_4 - - - - 0.000000000000000000001222 96.0
CSH3_k127_4772008_5 - - - - 0.000008618 52.0
CSH3_k127_4819306_0 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 476.0
CSH3_k127_4819306_1 Transposase IS116/IS110/IS902 family - - - 0.00001663 48.0
CSH3_k127_4819306_2 Transposase IS200 like K07491 - - 0.0002151 48.0
CSH3_k127_4843265_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.397e-224 705.0
CSH3_k127_4843265_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.37e-221 694.0
CSH3_k127_4843265_10 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 299.0
CSH3_k127_4843265_11 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 289.0
CSH3_k127_4843265_12 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002719 253.0
CSH3_k127_4843265_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
CSH3_k127_4843265_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000007444 218.0
CSH3_k127_4843265_15 TIGRFAM ribosomal protein L30P K02907 - - 0.0000000000000000000000000000000000000000000000000000000000378 208.0
CSH3_k127_4843265_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000009142 200.0
CSH3_k127_4843265_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000003643 198.0
CSH3_k127_4843265_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000002805 178.0
CSH3_k127_4843265_19 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000003961 176.0
CSH3_k127_4843265_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 477.0
CSH3_k127_4843265_20 - - - - 0.00000000000000000000000000000000000000000000004684 183.0
CSH3_k127_4843265_21 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000001552 173.0
CSH3_k127_4843265_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000000000005972 164.0
CSH3_k127_4843265_23 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000002177 165.0
CSH3_k127_4843265_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000003695 149.0
CSH3_k127_4843265_25 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.0000000000000000000000000000000004052 134.0
CSH3_k127_4843265_26 PFAM Ribosomal protein K02912 - - 0.00000000000000000000000000000006002 130.0
CSH3_k127_4843265_27 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000638 124.0
CSH3_k127_4843265_28 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000021 99.0
CSH3_k127_4843265_29 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000000000000000891 94.0
CSH3_k127_4843265_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 424.0
CSH3_k127_4843265_30 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.0000000000000000001107 88.0
CSH3_k127_4843265_31 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000000258 84.0
CSH3_k127_4843265_32 Periplasmic or secreted lipoprotein - - - 0.000000000000001155 79.0
CSH3_k127_4843265_33 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000441 78.0
CSH3_k127_4843265_34 - - - - 0.00000000000004291 76.0
CSH3_k127_4843265_35 Transcription factor Pcc1 K09741 - - 0.0000000000357 66.0
CSH3_k127_4843265_36 Involved in regulation of DNA replication - - - 0.00000821 58.0
CSH3_k127_4843265_37 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000023 51.0
CSH3_k127_4843265_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 415.0
CSH3_k127_4843265_5 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 385.0
CSH3_k127_4843265_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 342.0
CSH3_k127_4843265_7 tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 353.0
CSH3_k127_4843265_8 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 304.0
CSH3_k127_4843265_9 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 303.0
CSH3_k127_4903255_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000003648 193.0
CSH3_k127_4903255_1 self proteolysis K03466,K06196,K12132 - 2.7.11.1 0.0000000000000004993 85.0
CSH3_k127_4905697_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 3.893e-264 822.0
CSH3_k127_4905697_1 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 2.538e-230 729.0
CSH3_k127_4905697_10 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000005082 133.0
CSH3_k127_4905697_11 - - - - 0.000000000000000000000006566 107.0
CSH3_k127_4905697_12 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes K03800 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000005331 103.0
CSH3_k127_4905697_13 - - - - 0.00000000000000000003897 104.0
CSH3_k127_4905697_14 - - - - 0.00000000000002749 79.0
CSH3_k127_4905697_15 - - - - 0.0000003744 57.0
CSH3_k127_4905697_16 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00007719 51.0
CSH3_k127_4905697_2 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 2.251e-221 698.0
CSH3_k127_4905697_3 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 460.0
CSH3_k127_4905697_4 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 402.0
CSH3_k127_4905697_5 cell wall organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 354.0
CSH3_k127_4905697_6 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004528 266.0
CSH3_k127_4905697_7 Membrane protein of unknown function DUF63 - - - 0.0000000000000000000000000000000000000000000000000000000000000003554 229.0
CSH3_k127_4905697_8 Belongs to the UPF0179 family K09730 - - 0.000000000000000000000000000000000000000002699 159.0
CSH3_k127_4905697_9 Stage II sporulation protein M K06384 - - 0.000000000000000000000000000000000008107 143.0
CSH3_k127_4911158_0 - K07039,K09933 - - 0.000000000000000000000000001335 124.0
CSH3_k127_4911158_1 Protein of unknown function (DUF1822) - - - 0.00000000000000000888 97.0
CSH3_k127_491708_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1122.0
CSH3_k127_491708_1 DNA methylase K07316 - 2.1.1.72 3.473e-194 624.0
CSH3_k127_491708_10 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.000000000000000000000000000000000000000000000000000000002726 207.0
CSH3_k127_491708_11 DNA methylase K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000002291 178.0
CSH3_k127_491708_12 - - - - 0.000000000000000000000000000006406 124.0
CSH3_k127_491708_13 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000003843 114.0
CSH3_k127_491708_14 CcmE K02197 - - 0.00000000001327 70.0
CSH3_k127_491708_16 - K06193 - - 0.0007284 46.0
CSH3_k127_491708_2 PFAM PilT protein domain protein K06865 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 595.0
CSH3_k127_491708_3 Has ATPase and non-specific DNA-binding activities K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 589.0
CSH3_k127_491708_4 MgtC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
CSH3_k127_491708_5 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002097 280.0
CSH3_k127_491708_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004355 273.0
CSH3_k127_491708_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000334 252.0
CSH3_k127_491708_8 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000001751 240.0
CSH3_k127_491708_9 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000549 217.0
CSH3_k127_4943246_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.033e-288 892.0
CSH3_k127_4943246_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 3.16e-268 839.0
CSH3_k127_4943246_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000005161 176.0
CSH3_k127_4943246_11 COG1361 S-layer domain - - - 0.000000000000000000000000000002485 135.0
CSH3_k127_4943246_12 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000001118 97.0
CSH3_k127_4943246_13 Psort location Cytoplasmic, score 8.96 K07491 - - 0.00000000000000000001232 95.0
CSH3_k127_4943246_14 NnrS protein - - - 0.000005756 52.0
CSH3_k127_4943246_2 FMN binding - - - 1.424e-261 813.0
CSH3_k127_4943246_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 402.0
CSH3_k127_4943246_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 333.0
CSH3_k127_4943246_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 320.0
CSH3_k127_4943246_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 306.0
CSH3_k127_4943246_7 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005658 269.0
CSH3_k127_4943246_8 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002035 260.0
CSH3_k127_4943246_9 Rhodanese Homology Domain K01011,K01613 - 2.8.1.1,2.8.1.2,4.1.1.65 0.00000000000000000000000000000000000000000000000000000008243 206.0
CSH3_k127_4945457_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 6.729e-200 641.0
CSH3_k127_4945457_1 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000701 198.0
CSH3_k127_4945457_2 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000000005338 177.0
CSH3_k127_497001_0 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 322.0
CSH3_k127_497001_1 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 292.0
CSH3_k127_497001_10 Uncharacterised protein family (UPF0175) - - - 0.000003652 51.0
CSH3_k127_497001_11 - - - - 0.00001164 54.0
CSH3_k127_497001_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004694 248.0
CSH3_k127_497001_3 protein conserved in archaea K09746 - - 0.00000000000000000000000000000347 131.0
CSH3_k127_497001_4 Deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE) that cause irreversible damage K05520 - 3.5.1.124 0.00000000000000000000000000007826 117.0
CSH3_k127_497001_5 - - - - 0.0000000000000000000003955 98.0
CSH3_k127_497001_6 Protein of unknown function (DUF1273) - - - 0.0000000000001436 76.0
CSH3_k127_497001_7 Macro domain - - - 0.0000000000003896 73.0
CSH3_k127_497001_8 - - - - 0.000000000004877 66.0
CSH3_k127_497001_9 Macro domain - - - 0.000000004699 59.0
CSH3_k127_505735_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 405.0
CSH3_k127_505735_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 340.0
CSH3_k127_505735_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000002748 103.0
CSH3_k127_505735_3 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000002889 54.0
CSH3_k127_5062796_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1178.0
CSH3_k127_5062796_1 Belongs to the MCM family K10726 - - 6.236e-268 841.0
CSH3_k127_5062796_10 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 338.0
CSH3_k127_5062796_11 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 312.0
CSH3_k127_5062796_12 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003534 275.0
CSH3_k127_5062796_13 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000004866 214.0
CSH3_k127_5062796_14 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000002747 170.0
CSH3_k127_5062796_15 COG0286 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 0.000000000000000000000000000000004074 128.0
CSH3_k127_5062796_16 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000002755 99.0
CSH3_k127_5062796_17 - - - - 0.0000000000000000000002997 101.0
CSH3_k127_5062796_18 - - - - 0.000000000000000002378 95.0
CSH3_k127_5062796_19 - - - - 0.000000000007037 74.0
CSH3_k127_5062796_2 SMART Elongator protein 3 MiaB NifB K22226 - - 9.626e-231 718.0
CSH3_k127_5062796_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.916e-213 677.0
CSH3_k127_5062796_4 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 612.0
CSH3_k127_5062796_5 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 452.0
CSH3_k127_5062796_6 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 410.0
CSH3_k127_5062796_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 384.0
CSH3_k127_5062796_8 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 357.0
CSH3_k127_5062796_9 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 360.0
CSH3_k127_508355_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1483.0
CSH3_k127_508355_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.112e-273 850.0
CSH3_k127_508355_10 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000004104 232.0
CSH3_k127_508355_11 PFAM ATPase, BadF BadG BcrA BcrD type K09680 - 2.7.1.33 0.00000000000000000000000000000000000000000000005994 177.0
CSH3_k127_508355_12 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000001542 134.0
CSH3_k127_508355_13 Gar1/Naf1 RNA binding region K07569 - - 0.0000000003749 65.0
CSH3_k127_508355_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 1.262e-218 687.0
CSH3_k127_508355_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 606.0
CSH3_k127_508355_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 573.0
CSH3_k127_508355_5 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 514.0
CSH3_k127_508355_6 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 481.0
CSH3_k127_508355_7 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 319.0
CSH3_k127_508355_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 284.0
CSH3_k127_508355_9 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
CSH3_k127_5093634_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 557.0
CSH3_k127_5093634_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 452.0
CSH3_k127_5093634_10 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000003827 132.0
CSH3_k127_5093634_11 Protein of unknown function (DUF429) K09147 - - 0.000000000000000000000000000000008731 130.0
CSH3_k127_5093634_12 Thymidylate kinase - - - 0.000000000000000000000000000005977 126.0
CSH3_k127_5093634_13 - - - - 0.0000000000000000000000001266 109.0
CSH3_k127_5093634_14 dUTPase - - - 0.000000000000009564 86.0
CSH3_k127_5093634_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
CSH3_k127_5093634_3 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 340.0
CSH3_k127_5093634_4 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 299.0
CSH3_k127_5093634_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000008533 248.0
CSH3_k127_5093634_6 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.000000000000000000000000000000000000000000000000000333 190.0
CSH3_k127_5093634_7 Protein of unknown function (DUF98) - - - 0.0000000000000000000000000000000000000000000000000008712 188.0
CSH3_k127_5093634_8 - - - - 0.0000000000000000000000000000000000000000000016 178.0
CSH3_k127_5093634_9 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000003855 169.0
CSH3_k127_5138145_0 helicase superfamily c-terminal domain - - - 1.924e-236 736.0
CSH3_k127_5138145_1 Protein of unknown function (DUF790) K09744 - - 8.191e-229 717.0
CSH3_k127_5138145_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000436 209.0
CSH3_k127_5138145_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001194 202.0
CSH3_k127_5138145_4 Transcriptional regulator, TrmB - - - 0.000000000000000000000000005383 114.0
CSH3_k127_5138145_5 HNH nucleases K07451 - - 0.00000000000000000000569 94.0
CSH3_k127_5138145_6 peptidyl-tyrosine sulfation - - - 0.00000000000000007447 89.0
CSH3_k127_5138145_7 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.000000000000001957 81.0
CSH3_k127_5183454_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 520.0
CSH3_k127_5183454_1 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 521.0
CSH3_k127_5183454_2 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 450.0
CSH3_k127_5183454_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 388.0
CSH3_k127_5183454_4 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000002099 269.0
CSH3_k127_5183454_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000005386 161.0
CSH3_k127_5183454_6 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000001682 145.0
CSH3_k127_5183454_7 Psort location Cytoplasmic, score 8.96 K07491 - - 0.000000001405 61.0
CSH3_k127_5208361_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.255e-289 916.0
CSH3_k127_5208361_1 TIGRFAM F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 319.0
CSH3_k127_5208361_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000000002849 233.0
CSH3_k127_5208361_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000008084 228.0
CSH3_k127_5259359_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 579.0
CSH3_k127_5259359_1 PFAM DNA RNA helicase, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 323.0
CSH3_k127_5259359_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000187 87.0
CSH3_k127_5259359_3 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000000000001906 79.0
CSH3_k127_5259359_4 Transposase DDE domain K07492 - - 0.00000000000006958 71.0
CSH3_k127_5278512_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 403.0
CSH3_k127_5278512_1 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 344.0
CSH3_k127_5278512_10 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000614 109.0
CSH3_k127_5278512_11 Belongs to the UPF0216 family K09737 - - 0.00000000000000000000002538 106.0
CSH3_k127_5278512_12 cheY-homologous receiver domain K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000343 96.0
CSH3_k127_5278512_13 integral membrane protein - - - 0.00000000000439 73.0
CSH3_k127_5278512_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 309.0
CSH3_k127_5278512_3 ATP-grasp domain K06913 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 304.0
CSH3_k127_5278512_4 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000000000000005073 225.0
CSH3_k127_5278512_5 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000006055 196.0
CSH3_k127_5278512_6 COG0455 ATPases involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000000000008535 189.0
CSH3_k127_5278512_7 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.00000000000000000000000000000000000000000003933 164.0
CSH3_k127_5278512_8 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000008604 162.0
CSH3_k127_5278512_9 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000003428 130.0
CSH3_k127_5306554_0 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 479.0
CSH3_k127_5306554_1 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000001012 250.0
CSH3_k127_5317244_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 2.98e-225 708.0
CSH3_k127_5354684_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 491.0
CSH3_k127_5354684_1 type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 475.0
CSH3_k127_5354684_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 389.0
CSH3_k127_5354684_3 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 322.0
CSH3_k127_5354684_4 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000001066 216.0
CSH3_k127_5354684_5 Rubrerythrin - - - 0.00000000000000000000000000000006349 127.0
CSH3_k127_5369880_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 434.0
CSH3_k127_5369880_1 FlgD Ig-like domain K21449 - - 0.000000000000000000000000000002694 132.0
CSH3_k127_5369925_0 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000452 245.0
CSH3_k127_5369925_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000008042 170.0
CSH3_k127_5369925_2 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000001806 150.0
CSH3_k127_5369925_3 PFAM ribosomal protein S8E K02995 - - 0.000000000000000000000000000000000002062 141.0
CSH3_k127_5369925_4 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000008134 70.0
CSH3_k127_5400404_0 Radical SAM K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 501.0
CSH3_k127_5400404_1 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000000000000000000000000000000008845 195.0
CSH3_k127_5400404_2 CoA binding domain K06929 - - 0.0000000000000000000000000000000000006097 143.0
CSH3_k127_5402463_0 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 578.0
CSH3_k127_5402463_1 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003477 276.0
CSH3_k127_5402463_2 - - - - 0.0000000000000000000000000000000000000001479 160.0
CSH3_k127_5402463_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000001105 84.0
CSH3_k127_5412475_0 DEAD DEAH box helicase K06877 - - 0.0 1025.0
CSH3_k127_5412475_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 475.0
CSH3_k127_5412475_10 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000001978 90.0
CSH3_k127_5412475_11 - - - - 0.00000000001515 68.0
CSH3_k127_5412475_12 DNA primase - - - 0.00000000008867 75.0
CSH3_k127_5412475_13 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.0001124 46.0
CSH3_k127_5412475_2 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 447.0
CSH3_k127_5412475_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 442.0
CSH3_k127_5412475_4 DEAD DEAH box helicase domain protein K10896 - - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
CSH3_k127_5412475_5 Domain of unknown function (DUF932) - - - 0.0000000000000000000000000000000000000000000000000000000363 209.0
CSH3_k127_5412475_6 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.000000000000000000000000000000000000000000000001852 196.0
CSH3_k127_5412475_7 Pfam:Gp37_Gp68 - - - 0.000000000000000000000000000000000000001543 156.0
CSH3_k127_5412475_8 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000005942 122.0
CSH3_k127_5412475_9 - - - - 0.00000000000000000000128 100.0
CSH3_k127_5419668_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1.348e-318 990.0
CSH3_k127_5419668_1 RuvA, C-terminal domain K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000133 171.0
CSH3_k127_5419668_2 PFAM regulatory protein, ArsR K07721 - - 0.00000000000000000000000000000000000000000001929 168.0
CSH3_k127_5419668_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000001703 118.0
CSH3_k127_5419668_4 Transposase DDE domain - - - 0.000000000001981 80.0
CSH3_k127_5465809_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001344 228.0
CSH3_k127_5465809_1 Transcriptional regulator, AbrB family K06193 - - 0.0000000000000000000000000000002421 124.0
CSH3_k127_5465809_2 - - - - 0.0000000000000001495 81.0
CSH3_k127_5465809_3 Transcriptional regulator - - - 0.00000000000001792 78.0
CSH3_k127_5465809_4 oligosaccharyl transferase STT3 subunit - - - 0.00001596 55.0
CSH3_k127_5487981_0 transposase K07492 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 284.0
CSH3_k127_5487981_1 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 259.0
CSH3_k127_5487981_2 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000502 256.0
CSH3_k127_5487981_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000004844 109.0
CSH3_k127_5499684_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.648e-318 990.0
CSH3_k127_5499684_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 2.4e-223 701.0
CSH3_k127_5499684_10 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000004451 181.0
CSH3_k127_5499684_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000005201 147.0
CSH3_k127_5499684_12 transcriptional K07729 - - 0.00000000000000000000007225 104.0
CSH3_k127_5499684_13 TIGRFAM Protein of - - - 0.000000000000005172 77.0
CSH3_k127_5499684_14 Protein of unknown function DUF134 - - - 0.000000006274 58.0
CSH3_k127_5499684_15 - - - - 0.000000007482 63.0
CSH3_k127_5499684_16 - - - - 0.00000003374 64.0
CSH3_k127_5499684_17 TIGRFAM cation diffusion facilitator family transporter - - - 0.00004516 48.0
CSH3_k127_5499684_2 SMART Elongator protein 3 MiaB NifB - - - 6.332e-209 662.0
CSH3_k127_5499684_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 474.0
CSH3_k127_5499684_4 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 430.0
CSH3_k127_5499684_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000008506 238.0
CSH3_k127_5499684_6 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000116 222.0
CSH3_k127_5499684_7 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000001337 202.0
CSH3_k127_5499684_8 KaiC - - - 0.0000000000000000000000000000000000000000000000000001441 197.0
CSH3_k127_5499684_9 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.0000000000000000000000000000000000000000000000000004224 197.0
CSH3_k127_553802_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 2.476e-217 685.0
CSH3_k127_553802_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.523e-199 625.0
CSH3_k127_553802_10 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
CSH3_k127_553802_11 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001259 253.0
CSH3_k127_553802_12 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000003077 214.0
CSH3_k127_553802_13 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000001573 194.0
CSH3_k127_553802_14 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000001344 164.0
CSH3_k127_553802_15 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000001721 151.0
CSH3_k127_553802_16 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000004128 138.0
CSH3_k127_553802_17 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000001824 124.0
CSH3_k127_553802_18 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000003537 122.0
CSH3_k127_553802_19 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000006788 126.0
CSH3_k127_553802_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 596.0
CSH3_k127_553802_20 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.0000000000000000003644 89.0
CSH3_k127_553802_21 structural constituent of ribosome K02962 - - 0.000000000005084 68.0
CSH3_k127_553802_22 - - - - 0.000000003247 61.0
CSH3_k127_553802_23 Protein of unknown function (DUF3795) - - - 0.00008835 48.0
CSH3_k127_553802_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 509.0
CSH3_k127_553802_4 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 445.0
CSH3_k127_553802_5 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 441.0
CSH3_k127_553802_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 407.0
CSH3_k127_553802_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 384.0
CSH3_k127_553802_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 380.0
CSH3_k127_553802_9 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 332.0
CSH3_k127_5555482_0 Putative Ig domain - - - 0.00000000000000000000000000000000000000001778 177.0
CSH3_k127_5555482_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000008557 155.0
CSH3_k127_5555482_2 ISXO2-like transposase domain - - - 0.00000000000000000000000000000000004244 137.0
CSH3_k127_5555482_3 Domain of unknown function (DUF4082) - - - 0.000000000000000000000002371 121.0
CSH3_k127_5620546_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 486.0
CSH3_k127_5620546_1 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008118 254.0
CSH3_k127_5620546_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000001971 216.0
CSH3_k127_5620546_3 RibD C-terminal domain K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000703 170.0
CSH3_k127_5620546_4 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000006208 129.0
CSH3_k127_5620546_5 PFAM RibD C-terminal domain K14654 - 1.1.1.302 0.00000001304 59.0
CSH3_k127_564109_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.862e-215 681.0
CSH3_k127_564109_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000009213 154.0
CSH3_k127_564109_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000005603 103.0
CSH3_k127_564310_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1234.0
CSH3_k127_564310_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1213.0
CSH3_k127_564310_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000005672 142.0
CSH3_k127_564310_11 Protein of unknown function (DUF1284) K09706 - - 0.000000000000000000000000000001436 124.0
CSH3_k127_564310_12 PFAM Tetratricopeptide repeat - - - 0.00001536 55.0
CSH3_k127_564310_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 6.803e-196 619.0
CSH3_k127_564310_3 GDP dissociation inhibitor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 571.0
CSH3_k127_564310_4 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 460.0
CSH3_k127_564310_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 409.0
CSH3_k127_564310_6 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 384.0
CSH3_k127_564310_7 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000005363 215.0
CSH3_k127_564310_8 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001795 210.0
CSH3_k127_564310_9 - - - - 0.00000000000000000000000000000000000001294 156.0
CSH3_k127_565373_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 4.487e-213 674.0
CSH3_k127_565373_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 3.76e-201 642.0
CSH3_k127_565373_10 Major facilitator superfamily K19576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007331 259.0
CSH3_k127_565373_11 S-layer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001801 262.0
CSH3_k127_565373_12 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000001062 191.0
CSH3_k127_565373_13 membrane-associated protein domain - - - 0.000000000000000000000000009822 123.0
CSH3_k127_565373_14 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000005396 106.0
CSH3_k127_565373_15 but it may be involved in stabilization of the trimeric complex - - - 0.00000000001184 66.0
CSH3_k127_565373_16 - K06193 - - 0.0007219 46.0
CSH3_k127_565373_2 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 527.0
CSH3_k127_565373_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 487.0
CSH3_k127_565373_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 464.0
CSH3_k127_565373_5 Domain of unknown function (DUF1743) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 384.0
CSH3_k127_565373_6 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 355.0
CSH3_k127_565373_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 336.0
CSH3_k127_565373_8 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 301.0
CSH3_k127_565373_9 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 280.0
CSH3_k127_5753182_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001298 303.0
CSH3_k127_5753182_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000267 192.0
CSH3_k127_5753182_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000002456 175.0
CSH3_k127_5753182_3 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000001131 154.0
CSH3_k127_5753182_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162 - 1.2.4.1 0.00000000000000000003331 93.0
CSH3_k127_5796108_0 membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 413.0
CSH3_k127_5796108_1 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000002163 211.0
CSH3_k127_5796108_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000007045 186.0
CSH3_k127_5796108_3 nucleic acid-binding protein, contains PIN domain K07065 - - 0.0000000000000000000000002152 110.0
CSH3_k127_5796108_4 transcriptional - - - 0.000000000000009209 86.0
CSH3_k127_5796108_5 Tellurite resistance protein TehB - - - 0.00000000000002322 74.0
CSH3_k127_5796108_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000678 77.0
CSH3_k127_5796108_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - 0.0003578 51.0
CSH3_k127_5796108_8 Transcriptional regulator, TrmB - - - 0.0004119 48.0
CSH3_k127_5807217_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 527.0
CSH3_k127_5807217_1 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 427.0
CSH3_k127_5807217_10 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit - GO:0008150,GO:0008152,GO:0009058,GO:0042618,GO:0042619,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.00000001038 64.0
CSH3_k127_5807217_11 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000001565 66.0
CSH3_k127_5807217_12 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000002827 65.0
CSH3_k127_5807217_13 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000003431 59.0
CSH3_k127_5807217_2 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
CSH3_k127_5807217_3 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001727 256.0
CSH3_k127_5807217_4 TIGRFAM CRISPR-associated RAMP protein - - - 0.0000000000000000000000000000000000000000001042 167.0
CSH3_k127_5807217_5 TIGRFAM CRISPR-associated RAMP protein - - - 0.000000000000000000000000000000000000006717 158.0
CSH3_k127_5807217_6 transposase K07492 - - 0.0000000000000000000000000000000004233 132.0
CSH3_k127_5807217_7 PFAM Helicase conserved C-terminal domain - - - 0.00000000000000000000000000000004335 126.0
CSH3_k127_5807217_8 transposase K07492 - - 0.0000000000000000000000000007977 115.0
CSH3_k127_5807217_9 Transposase DDE domain K07492 - - 0.000000000000004192 74.0
CSH3_k127_5904034_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.064e-245 766.0
CSH3_k127_5904034_1 HEPN domain - - - 0.000000000000000000000000000000000999 133.0
CSH3_k127_5904034_2 Nucleotidyltransferase domain - - - 0.0000000000000005805 81.0
CSH3_k127_5904034_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000001633 72.0
CSH3_k127_5904034_4 - - - - 0.000000006114 67.0
CSH3_k127_5904034_5 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0001485 45.0
CSH3_k127_5907209_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 448.0
CSH3_k127_5907209_1 - - - - 0.0000000000002594 76.0
CSH3_k127_5990489_0 PFAM SEC-C motif K09858 - - 0.000000001128 61.0
CSH3_k127_5995696_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 5.017e-204 642.0
CSH3_k127_5995696_1 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000005717 134.0
CSH3_k127_5995696_2 all-trans-retinol 13,14-reductase activity - - - 0.000004655 57.0
CSH3_k127_601126_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.000000000000007984 83.0
CSH3_k127_601126_2 Lrp/AsnC ligand binding domain - - - 0.00004945 50.0
CSH3_k127_601126_3 Lrp/AsnC ligand binding domain - - - 0.0002481 53.0
CSH3_k127_6063257_0 N-4 methylation of cytosine K00590 - 2.1.1.113 2.667e-202 640.0
CSH3_k127_6063257_1 Restriction endonuclease BsobI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 387.0
CSH3_k127_6063257_2 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 346.0
CSH3_k127_6063257_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002735 260.0
CSH3_k127_6063257_4 COG1078 HD superfamily phosphohydrolases K06885 - - 0.000000000000000000173 101.0
CSH3_k127_6074449_0 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000005387 178.0
CSH3_k127_6074449_1 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000006967 155.0
CSH3_k127_6074449_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000001164 146.0
CSH3_k127_6074449_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000347 91.0
CSH3_k127_6074449_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000003133 88.0
CSH3_k127_6081085_0 WD40 repeat, subgroup - - - 0.0 1400.0
CSH3_k127_6081085_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 579.0
CSH3_k127_6081085_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 505.0
CSH3_k127_6081085_3 PFAM NAD dependent epimerase dehydratase family K01784,K02473,K08678 - 4.1.1.35,5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 303.0
CSH3_k127_6081085_4 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 289.0
CSH3_k127_6081085_5 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000001074 208.0
CSH3_k127_6081085_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000002373 159.0
CSH3_k127_6081085_7 domain protein - - - 0.000000001814 73.0
CSH3_k127_6114287_0 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 606.0
CSH3_k127_6114287_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 486.0
CSH3_k127_6114287_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 329.0
CSH3_k127_6114287_3 - - - - 0.0000000000000000000000000000000000003326 151.0
CSH3_k127_6114287_4 Nodulation protein S (NodS) - - - 0.000000000000006073 84.0
CSH3_k127_6114287_5 Uncharacterized protein conserved in archaea (DUF2119) - - - 0.0000009622 53.0
CSH3_k127_6114287_6 ADP-ribosylglycohydrolase - - - 0.000307 45.0
CSH3_k127_6128593_0 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 435.0
CSH3_k127_6128593_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 425.0
CSH3_k127_6128593_2 HTH-type transcriptional regulatory protein K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 303.0
CSH3_k127_6128593_3 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
CSH3_k127_6128593_4 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.00000000000000000000000000000000000000001425 157.0
CSH3_k127_6128593_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000001308 118.0
CSH3_k127_6128593_6 - - - - 0.000000000000000000006827 95.0
CSH3_k127_6128593_7 Encoded by - - - 0.000000000003827 70.0
CSH3_k127_6165680_0 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 385.0
CSH3_k127_6165680_1 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 320.0
CSH3_k127_6165680_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000001434 87.0
CSH3_k127_6165680_3 Protein of unknown function (DUF2769) - - - 0.000000000003413 70.0
CSH3_k127_6165685_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 552.0
CSH3_k127_6165685_1 PFAM Radical SAM domain protein K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 368.0
CSH3_k127_6165685_10 HTH DNA binding domain - - - 0.0000000000000000001332 96.0
CSH3_k127_6165685_11 Pfam:DUF1628 - - - 0.000000007863 62.0
CSH3_k127_6165685_12 - - - - 0.00001063 51.0
CSH3_k127_6165685_13 metal cluster binding K06940 - - 0.00004737 53.0
CSH3_k127_6165685_2 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000285 251.0
CSH3_k127_6165685_3 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000000000000001901 208.0
CSH3_k127_6165685_4 - - - - 0.00000000000000000000000000000000003723 139.0
CSH3_k127_6165685_5 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000000000824 126.0
CSH3_k127_6165685_6 - - - - 0.00000000000000000000000000003194 123.0
CSH3_k127_6165685_7 Transposase K07492 - - 0.00000000000000000000000000006955 119.0
CSH3_k127_6165685_8 Transposase DDE domain - - - 0.00000000000000000000000003161 109.0
CSH3_k127_6165685_9 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000000000000000000000002713 112.0
CSH3_k127_6165933_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 2.389e-294 916.0
CSH3_k127_6165933_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.098e-291 904.0
CSH3_k127_6165933_10 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 452.0
CSH3_k127_6165933_11 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 440.0
CSH3_k127_6165933_12 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 413.0
CSH3_k127_6165933_13 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 396.0
CSH3_k127_6165933_14 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 387.0
CSH3_k127_6165933_15 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 374.0
CSH3_k127_6165933_16 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 370.0
CSH3_k127_6165933_17 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 364.0
CSH3_k127_6165933_18 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 360.0
CSH3_k127_6165933_19 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 358.0
CSH3_k127_6165933_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 8.273e-244 764.0
CSH3_k127_6165933_20 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
CSH3_k127_6165933_21 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 326.0
CSH3_k127_6165933_22 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 305.0
CSH3_k127_6165933_23 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 303.0
CSH3_k127_6165933_24 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002023 286.0
CSH3_k127_6165933_25 tRNAHis guanylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004467 268.0
CSH3_k127_6165933_26 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002522 263.0
CSH3_k127_6165933_27 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.0000000000000000000000000000000000000000000000000000000000000000000000003158 282.0
CSH3_k127_6165933_28 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000009411 240.0
CSH3_k127_6165933_29 Acetyl xylan esterase (AXE1) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000004842 242.0
CSH3_k127_6165933_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 591.0
CSH3_k127_6165933_30 Domain of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
CSH3_k127_6165933_31 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000001188 218.0
CSH3_k127_6165933_32 TIGRFAM archaeoflavoprotein AfpA - - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
CSH3_k127_6165933_33 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000001169 204.0
CSH3_k127_6165933_34 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000000000000003208 193.0
CSH3_k127_6165933_35 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001461 181.0
CSH3_k127_6165933_36 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000002882 170.0
CSH3_k127_6165933_37 eRF1 domain 2 - - - 0.0000000000000000000000000000000000000000006267 169.0
CSH3_k127_6165933_38 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000008258 156.0
CSH3_k127_6165933_39 - - - - 0.0000000000000000000000000000006098 141.0
CSH3_k127_6165933_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 584.0
CSH3_k127_6165933_40 S-layer protein - - - 0.0000000000000000000000000002106 135.0
CSH3_k127_6165933_41 binds to the 23S rRNA K02921 - - 0.000000000000000000000000003104 114.0
CSH3_k127_6165933_42 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000006293 106.0
CSH3_k127_6165933_43 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0000000000000000000001246 106.0
CSH3_k127_6165933_44 - - - - 0.00000000000000000000522 99.0
CSH3_k127_6165933_45 PFAM PRC-barrel domain - - - 0.00000000000000000001312 95.0
CSH3_k127_6165933_46 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000008891 93.0
CSH3_k127_6165933_47 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000001984 87.0
CSH3_k127_6165933_48 Probably involved in the biogenesis of the ribosome K14561 - - 0.00000000000000278 81.0
CSH3_k127_6165933_49 - - - - 0.000000000002695 71.0
CSH3_k127_6165933_5 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 571.0
CSH3_k127_6165933_50 metal-dependent protease of the PAD1 JAB1 superfamily K20110 - 3.4.19.15 0.00000000003727 70.0
CSH3_k127_6165933_51 Poly(R)-hydroxyalkanoic acid synthase class III PhaE subunit - GO:0008150,GO:0008152,GO:0009058,GO:0042618,GO:0042619,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.0000001621 60.0
CSH3_k127_6165933_52 - - - - 0.0000007241 60.0
CSH3_k127_6165933_53 - - - - 0.0005401 43.0
CSH3_k127_6165933_6 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 547.0
CSH3_k127_6165933_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 535.0
CSH3_k127_6165933_8 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 527.0
CSH3_k127_6165933_9 serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 479.0
CSH3_k127_6170733_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.105e-295 919.0
CSH3_k127_6170733_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 522.0
CSH3_k127_6170733_2 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
CSH3_k127_6170733_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 392.0
CSH3_k127_6170733_4 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 390.0
CSH3_k127_6170733_5 Domain of unknown function (DUF4870) - - - 0.000000000000000000000000000485 118.0
CSH3_k127_6170733_6 ISXO2-like transposase domain - - - 0.00000000000000000000000004391 111.0
CSH3_k127_6211346_0 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000002247 87.0
CSH3_k127_6211346_1 Nucleotidyltransferase domain K07076 - - 0.0000000000004479 70.0
CSH3_k127_6211346_2 Domain of unknown function - - - 0.000000009908 69.0
CSH3_k127_6211346_3 PFAM BNR Asp-box repeat - - - 0.00001304 59.0
CSH3_k127_6214251_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 589.0
CSH3_k127_6214251_1 COG3497 Phage tail sheath protein FI K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 439.0
CSH3_k127_6214251_10 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000002828 141.0
CSH3_k127_6214251_11 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000001477 119.0
CSH3_k127_6214251_12 - - - - 0.00000000000000001593 83.0
CSH3_k127_6214251_2 Phage protein D - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000223 280.0
CSH3_k127_6214251_3 PFAM Phage-related baseplate assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
CSH3_k127_6214251_4 PAAR motif - - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
CSH3_k127_6214251_5 phage tail region protein - - - 0.00000000000000000000000000000000000000000000000000000001375 200.0
CSH3_k127_6214251_6 Baseplate J-like protein - - - 0.0000000000000000000000000000000000000000000000000000004287 216.0
CSH3_k127_6214251_7 - - - - 0.00000000000000000000000000000000000000000000000000009232 188.0
CSH3_k127_6214251_8 PFAM T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000005226 178.0
CSH3_k127_6214251_9 LysM domain - - - 0.0000000000000000000000000000000000000000000003984 174.0
CSH3_k127_6230474_0 Aconitate B N-terminal domain K01682 - 4.2.1.3,4.2.1.99 3.516e-317 990.0
CSH3_k127_6230474_1 DEAD DEAH box helicase K03654 - 3.6.4.12 7.91e-257 812.0
CSH3_k127_6230474_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 325.0
CSH3_k127_6230474_11 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
CSH3_k127_6230474_12 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 301.0
CSH3_k127_6230474_13 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 289.0
CSH3_k127_6230474_14 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001512 279.0
CSH3_k127_6230474_15 binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002565 252.0
CSH3_k127_6230474_16 Necessary for normal cell division and for the maintenance of normal septation - - - 0.000000000000000000000000000000000000000000000000000000000003722 213.0
CSH3_k127_6230474_17 - - - - 0.0000000000000000000000000000000000000000000000000000002447 207.0
CSH3_k127_6230474_18 PFAM conserved - - - 0.0000000000000000000000000000000000000000003343 162.0
CSH3_k127_6230474_19 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000000000000000000000000000000000444 151.0
CSH3_k127_6230474_2 PFAM ABC transporter K00400 - - 2.747e-239 749.0
CSH3_k127_6230474_20 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000003221 159.0
CSH3_k127_6230474_21 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000005272 121.0
CSH3_k127_6230474_22 protein conserved in archaea - - - 0.0000000000000000000000000008972 122.0
CSH3_k127_6230474_23 peptidyl-tyrosine sulfation - - - 0.000000000004607 72.0
CSH3_k127_6230474_24 Domain of unknown function (DUF1894) - - - 0.000000000666 63.0
CSH3_k127_6230474_25 Domain of unknown function DUF22 - - - 0.000000001357 64.0
CSH3_k127_6230474_26 - K00507 - 1.14.19.1 0.000000003905 68.0
CSH3_k127_6230474_27 - - - - 0.00000003252 56.0
CSH3_k127_6230474_28 Protein of unknown function DUF134 K06933 - - 0.0000001271 55.0
CSH3_k127_6230474_29 Family of unknown function (DUF5320) - - - 0.000007298 50.0
CSH3_k127_6230474_3 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 3.058e-205 651.0
CSH3_k127_6230474_30 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0001616 46.0
CSH3_k127_6230474_31 Tetratricopeptide TPR_2 repeat protein - - - 0.0007388 49.0
CSH3_k127_6230474_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 513.0
CSH3_k127_6230474_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
CSH3_k127_6230474_6 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
CSH3_k127_6230474_7 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 349.0
CSH3_k127_6230474_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 342.0
CSH3_k127_6230474_9 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 330.0
CSH3_k127_6231170_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 316.0
CSH3_k127_6231170_1 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.000000000000000000000000000000000000000000000000000000000000000003639 231.0
CSH3_k127_6231170_2 - - - - 0.00000000000000000000000000000008337 132.0
CSH3_k127_6251403_0 PFAM Kelch repeat type 1 K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000007921 256.0
CSH3_k127_6251403_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000003908 209.0
CSH3_k127_6251403_2 cell adhesion involved in biofilm formation K02014,K11031 - - 0.0000000000000000000000000009465 132.0
CSH3_k127_6251403_3 Fibronectin type 3 domain - - - 0.0000000000000000000005421 113.0
CSH3_k127_6251403_4 Domain of unknown function (DUF2341) - - - 0.000000000006261 80.0
CSH3_k127_6251403_5 DDE superfamily endonuclease K07494,K07499 - - 0.00000008033 55.0
CSH3_k127_6256314_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 5.442e-303 951.0
CSH3_k127_6256314_1 in RNase L inhibitor, RLI K06174 - - 8.405e-267 832.0
CSH3_k127_6256314_10 Transcriptional regulator, AbrB family - - - 0.0000000000000000000000000000000000000000007273 159.0
CSH3_k127_6256314_11 - - - - 0.000000000000000000000000000000000008379 141.0
CSH3_k127_6256314_12 - - - - 0.00000000000000000000004769 100.0
CSH3_k127_6256314_13 RNase L inhibitor, RLI - - - 0.0000000000000000000001052 101.0
CSH3_k127_6256314_14 - - - - 0.000000000002177 68.0
CSH3_k127_6256314_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 7.872e-215 675.0
CSH3_k127_6256314_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 1.595e-206 649.0
CSH3_k127_6256314_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 416.0
CSH3_k127_6256314_5 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 304.0
CSH3_k127_6256314_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 290.0
CSH3_k127_6256314_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
CSH3_k127_6256314_8 - - - - 0.00000000000000000000000000000000000000000000000000000007021 199.0
CSH3_k127_6256314_9 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000003356 184.0
CSH3_k127_6278669_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1022.0
CSH3_k127_6278669_1 PFAM type II secretion system protein E K07332 - - 3.332e-210 666.0
CSH3_k127_6278669_10 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 315.0
CSH3_k127_6278669_11 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 304.0
CSH3_k127_6278669_12 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 288.0
CSH3_k127_6278669_13 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002518 276.0
CSH3_k127_6278669_14 KaiC K07331 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
CSH3_k127_6278669_15 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000006363 231.0
CSH3_k127_6278669_16 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000000000000000000000000001526 194.0
CSH3_k127_6278669_17 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000006897 173.0
CSH3_k127_6278669_18 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000001966 149.0
CSH3_k127_6278669_19 CheC inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000001161 149.0
CSH3_k127_6278669_2 Chemotaxis protein CheA K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 561.0
CSH3_k127_6278669_20 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000005555 138.0
CSH3_k127_6278669_21 Archaebacterial flagellin K07330 - - 0.000000000000000000000000000000002706 133.0
CSH3_k127_6278669_22 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000007054 109.0
CSH3_k127_6278669_23 archaeal flagellar protein F K07329 - - 0.0000005596 56.0
CSH3_k127_6278669_24 - - - - 0.000001185 54.0
CSH3_k127_6278669_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 486.0
CSH3_k127_6278669_4 type II secretion system protein K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 455.0
CSH3_k127_6278669_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 443.0
CSH3_k127_6278669_6 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 424.0
CSH3_k127_6278669_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 397.0
CSH3_k127_6278669_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 379.0
CSH3_k127_6278669_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 333.0
CSH3_k127_6282469_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.002e-305 959.0
CSH3_k127_6282469_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 1.946e-203 639.0
CSH3_k127_6282469_10 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003268 269.0
CSH3_k127_6282469_11 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000004267 240.0
CSH3_k127_6282469_12 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000004505 211.0
CSH3_k127_6282469_13 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000007995 205.0
CSH3_k127_6282469_14 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000000000000000000000000007627 199.0
CSH3_k127_6282469_15 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000879 151.0
CSH3_k127_6282469_16 PFAM pyridoxamine 5'-phosphate K07006 - - 0.00000000000000006197 85.0
CSH3_k127_6282469_17 - - - - 0.00000000002976 66.0
CSH3_k127_6282469_18 Nucleotidyltransferase domain K07076 - - 0.000003411 54.0
CSH3_k127_6282469_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 8.173e-200 632.0
CSH3_k127_6282469_3 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 391.0
CSH3_k127_6282469_4 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 377.0
CSH3_k127_6282469_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 361.0
CSH3_k127_6282469_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 342.0
CSH3_k127_6282469_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 327.0
CSH3_k127_6282469_8 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 310.0
CSH3_k127_6282469_9 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 290.0
CSH3_k127_629135_0 aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 523.0
CSH3_k127_629135_1 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 424.0
CSH3_k127_629135_10 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000004777 63.0
CSH3_k127_629135_11 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000007438 57.0
CSH3_k127_629135_2 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 390.0
CSH3_k127_629135_3 AAA domain K14949 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 308.0
CSH3_k127_629135_4 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 299.0
CSH3_k127_629135_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000001887 185.0
CSH3_k127_629135_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000001712 179.0
CSH3_k127_629135_7 Trm112p-like protein - - - 0.0000000000000000000000002017 106.0
CSH3_k127_629135_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000006129 80.0
CSH3_k127_629135_9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000001666 68.0
CSH3_k127_6301971_0 COG3385 FOG Transposase and inactivated derivatives K07495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 455.0
CSH3_k127_6301971_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 404.0
CSH3_k127_6301971_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 336.0
CSH3_k127_6301971_3 The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001133 149.0
CSH3_k127_6301971_4 PFAM MULE transposase, conserved domain - - - 0.0000000000000000018 100.0
CSH3_k127_6301971_5 to GB L77117 SP Q57808 PID 1499149 percent identity - - - 0.00000000000000639 75.0
CSH3_k127_6301971_6 - - - - 0.0007844 42.0
CSH3_k127_6353669_0 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000001301 239.0
CSH3_k127_6353669_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
CSH3_k127_6353669_2 PFAM Phosphatidylglycerophosphatase A - - - 0.000000000000000000000000000000000000000000000000000000000001416 216.0
CSH3_k127_6353669_3 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.0000000000000000000000000000000000000000000000000000001269 201.0
CSH3_k127_6353669_4 Belongs to the glycosyl hydrolase family 6 K01179,K20276,K21449 - 3.2.1.4 0.00000000000000000000000000000000000000000000000001638 198.0
CSH3_k127_6353669_5 Predicted permease K07089 - - 0.00000000000000000000000000001371 121.0
CSH3_k127_6353669_6 PAC2 family K07159 - - 0.0000000000000000002008 97.0
CSH3_k127_6362226_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1350.0
CSH3_k127_6362226_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 1.896e-313 968.0
CSH3_k127_6362226_10 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 461.0
CSH3_k127_6362226_11 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 394.0
CSH3_k127_6362226_12 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 393.0
CSH3_k127_6362226_13 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 390.0
CSH3_k127_6362226_14 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 389.0
CSH3_k127_6362226_15 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 368.0
CSH3_k127_6362226_17 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 353.0
CSH3_k127_6362226_18 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 351.0
CSH3_k127_6362226_19 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 342.0
CSH3_k127_6362226_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.703e-246 796.0
CSH3_k127_6362226_20 Rio2, N-terminal K07179 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 338.0
CSH3_k127_6362226_21 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 334.0
CSH3_k127_6362226_22 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 330.0
CSH3_k127_6362226_23 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 325.0
CSH3_k127_6362226_24 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 315.0
CSH3_k127_6362226_25 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K22162 - 1.5.7.2,1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 319.0
CSH3_k127_6362226_26 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 301.0
CSH3_k127_6362226_27 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 275.0
CSH3_k127_6362226_28 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007896 273.0
CSH3_k127_6362226_29 ATPases associated with a variety of cellular activities K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004512 254.0
CSH3_k127_6362226_3 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 3.191e-236 740.0
CSH3_k127_6362226_30 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000008542 245.0
CSH3_k127_6362226_31 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
CSH3_k127_6362226_32 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000001065 233.0
CSH3_k127_6362226_33 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000008623 221.0
CSH3_k127_6362226_34 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000219 194.0
CSH3_k127_6362226_35 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000233 190.0
CSH3_k127_6362226_36 transcription termination protein NusA K02600 - - 0.000000000000000000000000000000000000000000000000003827 184.0
CSH3_k127_6362226_37 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000003374 187.0
CSH3_k127_6362226_38 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000001658 157.0
CSH3_k127_6362226_39 Belongs to the UPF0146 family K09713 - - 0.000000000000000000000000000000000000001318 151.0
CSH3_k127_6362226_4 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.318e-217 680.0
CSH3_k127_6362226_40 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000001966 163.0
CSH3_k127_6362226_41 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000000000000008553 131.0
CSH3_k127_6362226_42 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000004259 116.0
CSH3_k127_6362226_43 Transport permease protein K09694 - - 0.00000000000000000000000003053 117.0
CSH3_k127_6362226_44 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000003383 91.0
CSH3_k127_6362226_45 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.00000000000000000234 87.0
CSH3_k127_6362226_46 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000003047 87.0
CSH3_k127_6362226_47 Family of unknown function (DUF5371) - - - 0.00000000000000001193 85.0
CSH3_k127_6362226_49 Uncharacterized ACR, COG1430 K09005 - - 0.000000009583 61.0
CSH3_k127_6362226_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 8.587e-203 636.0
CSH3_k127_6362226_50 - - - - 0.0002965 53.0
CSH3_k127_6362226_51 Possibly the antitoxin component of a - - - 0.0003276 44.0
CSH3_k127_6362226_6 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 527.0
CSH3_k127_6362226_7 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 521.0
CSH3_k127_6362226_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 504.0
CSH3_k127_6362226_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 493.0
CSH3_k127_6378805_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 588.0
CSH3_k127_6378805_1 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 523.0
CSH3_k127_6378805_10 - - - - 0.000000000000000000000000000000003187 142.0
CSH3_k127_6378805_11 PKD domain containing protein - - - 0.0000000000002643 82.0
CSH3_k127_6378805_12 membrane-bound metal-dependent K07038 - - 0.0001952 50.0
CSH3_k127_6378805_2 type II secretion system protein K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 407.0
CSH3_k127_6378805_3 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 404.0
CSH3_k127_6378805_4 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 389.0
CSH3_k127_6378805_5 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 358.0
CSH3_k127_6378805_6 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000097 257.0
CSH3_k127_6378805_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000007988 234.0
CSH3_k127_6378805_8 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000005518 226.0
CSH3_k127_6378805_9 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000009883 209.0
CSH3_k127_6407945_0 TIGRFAM small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 512.0
CSH3_k127_6407945_1 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 385.0
CSH3_k127_6407945_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
CSH3_k127_6407945_3 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000003655 209.0
CSH3_k127_6407945_4 Fibronectin type 3 domain - - - 0.000000000000000000000000604 116.0
CSH3_k127_6410030_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 4.117e-198 625.0
CSH3_k127_6410030_1 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 616.0
CSH3_k127_6410030_10 COG1361 S-layer domain - - - 0.000000000000000000000000000000000007918 152.0
CSH3_k127_6410030_11 transcriptional - - - 0.0000000000000000000000000000000004009 142.0
CSH3_k127_6410030_12 MMPL family K07003 - - 0.0000000000000000000000000000001008 138.0
CSH3_k127_6410030_13 - - - - 0.0000000000000000000000000000113 133.0
CSH3_k127_6410030_14 GYD domain - - - 0.000000000000000000000000002242 113.0
CSH3_k127_6410030_15 IMG reference gene - - - 0.0000000000001113 78.0
CSH3_k127_6410030_16 COG3316 Transposase and inactivated derivatives K07498 - - 0.00004956 48.0
CSH3_k127_6410030_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 520.0
CSH3_k127_6410030_3 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 453.0
CSH3_k127_6410030_4 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 392.0
CSH3_k127_6410030_5 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 320.0
CSH3_k127_6410030_6 phosphate transporter K16331 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000002437 238.0
CSH3_k127_6410030_7 Pfam:Arch_ATPase - - - 0.00000000000000000000000000000000000000000000000000009928 202.0
CSH3_k127_6410030_8 - - - - 0.00000000000000000000000000000000000000000000000001338 184.0
CSH3_k127_6410030_9 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000001935 194.0
CSH3_k127_6444644_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 0.0 1196.0
CSH3_k127_6444644_1 PFAM type II secretion system protein E K07332 - - 1.271e-237 755.0
CSH3_k127_6444644_2 type II secretion system protein K07333 - - 1.208e-225 716.0
CSH3_k127_6444644_3 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 467.0
CSH3_k127_6444644_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000411 272.0
CSH3_k127_6444644_5 - - - - 0.00000000000000000000000000000000000000007518 159.0
CSH3_k127_6444644_6 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000000000000000000000000003743 136.0
CSH3_k127_6444644_7 ABC-2 type transporter K09690 - - 0.0000000000000000000003046 97.0
CSH3_k127_6444644_8 - - - - 0.000000000001505 76.0
CSH3_k127_6473361_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 341.0
CSH3_k127_6473361_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 299.0
CSH3_k127_6473361_2 DUF72 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000147 282.0
CSH3_k127_6473361_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000002787 203.0
CSH3_k127_6473361_4 - - - - 0.000000000000000000000001604 108.0
CSH3_k127_6473361_5 Protein of unknown function (DUF429) - - - 0.000000000000000001737 89.0
CSH3_k127_6473361_6 Protein of unknown function DUF72 - - - 0.0000000000000003757 89.0
CSH3_k127_6473361_7 Homeodomain-like domain - - - 0.0000004408 51.0
CSH3_k127_6526385_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 532.0
CSH3_k127_6526385_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 480.0
CSH3_k127_6526385_10 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000002708 227.0
CSH3_k127_6526385_11 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001188 222.0
CSH3_k127_6526385_12 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000000000002068 246.0
CSH3_k127_6526385_13 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000000000000000005183 199.0
CSH3_k127_6526385_14 - - - - 0.000000000000000000000000000000006453 134.0
CSH3_k127_6526385_15 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000002733 100.0
CSH3_k127_6526385_16 VanZ like family - - - 0.00000000000000008689 96.0
CSH3_k127_6526385_17 - - - - 0.000000000000009105 83.0
CSH3_k127_6526385_19 best DB hits BLAST gb AAD45539.1 - - - 0.00000000002781 64.0
CSH3_k127_6526385_2 Glycosyl transferase family 4 K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 411.0
CSH3_k127_6526385_3 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 403.0
CSH3_k127_6526385_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 400.0
CSH3_k127_6526385_5 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 340.0
CSH3_k127_6526385_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 312.0
CSH3_k127_6526385_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 301.0
CSH3_k127_6526385_8 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
CSH3_k127_6526385_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007888 235.0
CSH3_k127_65436_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1044.0
CSH3_k127_65436_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 3.599e-292 905.0
CSH3_k127_65436_10 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
CSH3_k127_65436_11 Molydopterin dinucleotide binding domain K00203 - 1.2.7.12 0.0000000000000000000000000000000000000000000808 162.0
CSH3_k127_65436_12 lyase activity - - - 0.00000000000000000000003807 105.0
CSH3_k127_65436_13 ABC-type tungstate transport system, permease component K05772 - - 0.000000007226 61.0
CSH3_k127_65436_2 Molybdopterin oxidoreductase K00201 - 1.2.7.12 5.925e-231 720.0
CSH3_k127_65436_3 Domain of unknown function (DUF814) - - - 1.118e-201 647.0
CSH3_k127_65436_4 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 556.0
CSH3_k127_65436_5 4Fe-4S double cluster binding domain K00205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 461.0
CSH3_k127_65436_6 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 458.0
CSH3_k127_65436_7 PFAM Aldehyde dehydrogenase K00135,K18601 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 362.0
CSH3_k127_65436_8 GXGXG motif K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 337.0
CSH3_k127_65436_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000002644 236.0
CSH3_k127_6626208_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 605.0
CSH3_k127_6626208_1 Urocanase C-terminal domain K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 326.0
CSH3_k127_6626208_2 Belongs to the arginase family K01479,K12255 - 3.5.3.7,3.5.3.8 0.00000000000000000000000000000000000000000000000000004357 200.0
CSH3_k127_6626208_3 transposase IS200-family protein K07491 - - 0.00000000000131 71.0
CSH3_k127_6626208_4 Transposase IS200 like K07491 - - 0.0007365 43.0
CSH3_k127_6809939_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 456.0
CSH3_k127_699953_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.951e-213 668.0
CSH3_k127_699953_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 534.0
CSH3_k127_699953_2 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 345.0
CSH3_k127_699953_3 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000000005509 209.0
CSH3_k127_699953_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000003863 180.0
CSH3_k127_699953_5 DDE superfamily endonuclease - - - 0.000000000000101 70.0
CSH3_k127_71737_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 2.295e-218 686.0
CSH3_k127_71737_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 489.0
CSH3_k127_71737_2 Alpha/beta hydrolase family K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 410.0
CSH3_k127_71737_3 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 291.0
CSH3_k127_71737_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003054 278.0
CSH3_k127_71737_5 COG0694 Thioredoxin-like proteins and domains - - - 0.0002093 49.0
CSH3_k127_73469_0 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 589.0
CSH3_k127_73469_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 556.0
CSH3_k127_73469_2 AAA domain (Cdc48 subfamily) K07392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 418.0
CSH3_k127_73469_3 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 416.0
CSH3_k127_73469_4 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 401.0
CSH3_k127_73469_5 Helix-turn-helix domain protein K07731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 292.0
CSH3_k127_73469_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000002665 193.0
CSH3_k127_73469_7 PFAM response regulator receiver - - - 0.00000000000000004411 89.0
CSH3_k127_741093_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 445.0
CSH3_k127_741093_1 DNA ligase D, 3-phosphoesterase domain - - - 0.0000000000000000000000000000000000000000004637 162.0
CSH3_k127_741093_2 - - - - 0.000000000000000000000000000000000001093 143.0
CSH3_k127_741093_3 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000487 156.0
CSH3_k127_741093_4 - - - - 0.0000000000004453 79.0
CSH3_k127_741093_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K06919 - - 0.000000000001802 76.0
CSH3_k127_741093_7 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0001328 53.0
CSH3_k127_770107_0 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 464.0
CSH3_k127_770107_1 PFAM phosphatidate cytidylyltransferase - - - 0.000000000000000000000000000000000000000000000000000144 192.0
CSH3_k127_846559_0 Transcriptional regulator, TrmB - - - 0.000000000000000000000000123 111.0
CSH3_k127_846559_1 Transposase - - - 0.0000000000000000006596 87.0
CSH3_k127_879281_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 5.068e-212 667.0
CSH3_k127_879281_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 6.386e-199 629.0
CSH3_k127_879281_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 615.0
CSH3_k127_879281_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 501.0
CSH3_k127_879281_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000006658 229.0
CSH3_k127_879281_5 BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000005401 185.0
CSH3_k127_879281_6 DDE superfamily endonuclease - - - 0.0000000000000000000001853 102.0
CSH3_k127_879281_7 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000003989 49.0
CSH3_k127_92303_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1373.0
CSH3_k127_92303_1 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.00000000000000000000008069 105.0
CSH3_k127_92303_2 Short C-terminal domain K08982 - - 0.0000000000005034 71.0
CSH3_k127_92303_3 COG3316 Transposase and inactivated derivatives K07498 - - 0.0000000008907 63.0
CSH3_k127_92303_4 DNA-binding transcription factor activity K03892 - - 0.0001707 49.0
CSH3_k127_949117_0 PFAM DNA methylase N-4 N-6 K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 388.0
CSH3_k127_994688_0 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 376.0
CSH3_k127_994688_1 PFAM transposase IS66 K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001469 265.0