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Overview

ID MAG00641
Name CSH3_bin.5
Sample SMP0015
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanosarcinia
Order Methanosarcinales
Family Methanoperedenaceae
Genus Methanoperedens
Species Methanoperedens sp028679855
Assembly information
Completeness (%) 67.4
Contamination (%) 3.15
GC content (%) 46.0
N50 (bp) 3,849
Genome size (bp) 1,099,395

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1317

Gene name Description KEGG GOs EC E-value Score Sequence
CSH3_k127_1005380_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 597.0
CSH3_k127_1005380_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 397.0
CSH3_k127_1005380_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 257.0
CSH3_k127_1005380_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000001029 119.0
CSH3_k127_1006193_0 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000117 185.0
CSH3_k127_1006193_1 HD domain - - - 0.00000000000000000000000000000000000000001887 156.0
CSH3_k127_1006193_2 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000007589 132.0
CSH3_k127_1006193_3 thioesterase domain - - - 0.00000000000000000000000000005351 121.0
CSH3_k127_1006193_4 Ferric uptake regulator family K03711,K09825 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000008861 101.0
CSH3_k127_1006193_5 - - - - 0.00000002527 58.0
CSH3_k127_1006193_6 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00003,K01139 - 1.1.1.3,2.7.6.5,3.1.7.2 0.0000001244 54.0
CSH3_k127_1006493_0 trisaccharide binding K01768 - 4.6.1.1 1.926e-254 814.0
CSH3_k127_1006493_1 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 372.0
CSH3_k127_1006493_2 ATPase, AAA superfamily K06921 - - 0.0000000000000000000000000000000000000000000000000000000000243 214.0
CSH3_k127_1006493_3 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000003724 91.0
CSH3_k127_1006493_4 PFAM Archaeal ATPase - - - 0.000000000000000001584 89.0
CSH3_k127_1006493_5 PFAM YcfA-like protein - - - 0.000000000000000006624 85.0
CSH3_k127_1006493_6 TIR domain - - - 0.00000006699 59.0
CSH3_k127_1006493_7 TIR domain - - - 0.00000009682 56.0
CSH3_k127_1019024_0 Uncharacterized protein conserved in archaea (DUF2114) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 480.0
CSH3_k127_1019024_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 277.0
CSH3_k127_1019024_2 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001129 267.0
CSH3_k127_1038555_0 plastoquinone (Complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 522.0
CSH3_k127_1038555_1 plastoquinone (Complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 451.0
CSH3_k127_1038555_2 Formate hydrogenlyase subunit 4 K12138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 334.0
CSH3_k127_1038555_3 Hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000766 176.0
CSH3_k127_1038555_4 PFAM Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000008214 53.0
CSH3_k127_1040273_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 526.0
CSH3_k127_1040273_1 - - - - 0.000000000000000000000000000000003426 134.0
CSH3_k127_1040273_2 NurA - - - 0.00000000000000000000000000003528 119.0
CSH3_k127_1040273_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000817 73.0
CSH3_k127_1046844_0 Pfam:DUF2276 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 453.0
CSH3_k127_1046844_1 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 355.0
CSH3_k127_1046844_2 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000000000002108 211.0
CSH3_k127_1046844_3 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000002543 162.0
CSH3_k127_1046844_4 formate dehydrogenase - - - 0.00000000000000000000000000000005278 136.0
CSH3_k127_1056460_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 329.0
CSH3_k127_1071519_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 309.0
CSH3_k127_1071519_1 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007355 273.0
CSH3_k127_1086013_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 470.0
CSH3_k127_1086013_1 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 322.0
CSH3_k127_1086013_2 DNA polymerase LigD, polymerase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000002113 187.0
CSH3_k127_1086013_3 TIGRFAM type I restriction system adenine methylase (hsdM) K03427 - 2.1.1.72 0.000000000005434 70.0
CSH3_k127_1092167_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 369.0
CSH3_k127_1092167_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005186 245.0
CSH3_k127_1092167_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000003624 215.0
CSH3_k127_1092167_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000056 199.0
CSH3_k127_1092167_4 Belongs to the UPF0146 family K09713 - - 0.0000000000000000000000000000003688 124.0
CSH3_k127_1092167_5 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000001617 104.0
CSH3_k127_1092167_6 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.00000000000000005802 83.0
CSH3_k127_1093821_0 HsdM N-terminal domain K03427 - 2.1.1.72 6.81e-273 850.0
CSH3_k127_1093821_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 397.0
CSH3_k127_1093821_2 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000007559 194.0
CSH3_k127_1093821_3 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000004041 148.0
CSH3_k127_1104132_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 401.0
CSH3_k127_1104132_1 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 334.0
CSH3_k127_1104132_2 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000005984 214.0
CSH3_k127_1104132_3 ArsR transcriptional regulator - - - 0.0000001862 54.0
CSH3_k127_1111512_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
CSH3_k127_1111512_1 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 340.0
CSH3_k127_1111512_2 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 323.0
CSH3_k127_1111512_3 TIGRFAM phosphate ABC transporter K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 307.0
CSH3_k127_1111512_4 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000004505 211.0
CSH3_k127_1111512_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000005825 128.0
CSH3_k127_1125514_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009655 273.0
CSH3_k127_1125514_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000005052 188.0
CSH3_k127_1125514_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000006371 128.0
CSH3_k127_1130788_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000009958 225.0
CSH3_k127_1130788_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000007329 115.0
CSH3_k127_1130788_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000003617 116.0
CSH3_k127_1130788_3 COG0170 Dolichol kinase - - - 0.0000000000001738 78.0
CSH3_k127_1162723_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 588.0
CSH3_k127_1162723_1 PFAM ATP-NAD AcoX kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 316.0
CSH3_k127_1162723_2 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.0000000000756 66.0
CSH3_k127_1174068_0 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 477.0
CSH3_k127_1174068_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008062 256.0
CSH3_k127_1174068_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000001174 164.0
CSH3_k127_11887_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.491e-246 769.0
CSH3_k127_11887_1 Xylose isomerase-like TIM barrel - - - 0.0000168 47.0
CSH3_k127_1237715_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 342.0
CSH3_k127_1237715_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 327.0
CSH3_k127_1237715_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
CSH3_k127_1237715_3 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000000000000001296 154.0
CSH3_k127_1237715_4 Domain of unknown function (DUF3387) K01153 - 3.1.21.3 0.00000000000000000000005779 100.0
CSH3_k127_125556_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.392e-224 704.0
CSH3_k127_125556_1 DEAD DEAH box helicase domain protein K03725 - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 235.0
CSH3_k127_125556_2 DEAD DEAH box helicase domain protein K03725 - - 0.000000000000000000000000000000000000000000000000007121 185.0
CSH3_k127_125556_3 nuclear chromosome segregation - - - 0.00000000000009785 76.0
CSH3_k127_1272779_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 516.0
CSH3_k127_1272779_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 306.0
CSH3_k127_1272779_2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K22162 - 1.5.7.2,1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 304.0
CSH3_k127_1272779_3 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000008771 229.0
CSH3_k127_1272779_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000002451 89.0
CSH3_k127_1272779_5 Putative antitoxin - - - 0.00005495 48.0
CSH3_k127_129062_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 398.0
CSH3_k127_129062_1 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000001474 188.0
CSH3_k127_129062_2 HD domain - - - 0.00000000000000000000000000000000000000004863 155.0
CSH3_k127_129062_3 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000224 134.0
CSH3_k127_129062_4 Ferric uptake regulator family K09825 - - 0.00000000000000000009649 95.0
CSH3_k127_129062_5 - - - - 0.00000008984 57.0
CSH3_k127_1335880_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 8.099e-233 729.0
CSH3_k127_1335880_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 6.944e-197 622.0
CSH3_k127_1346733_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 586.0
CSH3_k127_1346733_1 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 295.0
CSH3_k127_1346733_2 TIGRFAM ribosomal protein L30P K02907 - - 0.0000000000000000000000000000000000000000000000000002566 188.0
CSH3_k127_1346733_3 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000005001 182.0
CSH3_k127_1346733_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000006601 180.0
CSH3_k127_1346733_5 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000001518 172.0
CSH3_k127_1346733_6 PFAM Ribosomal protein K02912 - - 0.0000000000000000000004465 97.0
CSH3_k127_135370_0 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
CSH3_k127_135370_1 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 301.0
CSH3_k127_135370_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 291.0
CSH3_k127_135370_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000002758 175.0
CSH3_k127_135370_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000003301 170.0
CSH3_k127_135370_5 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000001092 133.0
CSH3_k127_135370_6 - - - - 0.0000000000000000000000001181 107.0
CSH3_k127_135370_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000000001625 103.0
CSH3_k127_135370_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000000403 82.0
CSH3_k127_135370_9 Protein of unknown function (DUF473) K09135 - - 0.00000000003892 69.0
CSH3_k127_1378916_0 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000007001 218.0
CSH3_k127_1378916_1 - - - - 0.00000000000000004 84.0
CSH3_k127_1378916_2 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000008468 60.0
CSH3_k127_139933_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 454.0
CSH3_k127_139933_1 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 406.0
CSH3_k127_141105_0 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000004661 268.0
CSH3_k127_141105_1 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
CSH3_k127_141105_2 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
CSH3_k127_141105_3 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000876 142.0
CSH3_k127_141105_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000002595 127.0
CSH3_k127_141105_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0009645 43.0
CSH3_k127_144816_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.632e-275 855.0
CSH3_k127_144816_1 Belongs to the peptidase M50B family - - - 0.000005682 48.0
CSH3_k127_1461015_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 602.0
CSH3_k127_1461015_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 422.0
CSH3_k127_1461015_2 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 321.0
CSH3_k127_1461015_3 PFAM O-methyltransferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001908 221.0
CSH3_k127_1461015_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000004566 209.0
CSH3_k127_1461015_5 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000000000000000000000000199 164.0
CSH3_k127_1461015_6 - - - - 0.0003575 48.0
CSH3_k127_14901_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.714e-300 931.0
CSH3_k127_14901_1 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 513.0
CSH3_k127_14901_2 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000636 283.0
CSH3_k127_14901_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000001737 184.0
CSH3_k127_14901_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000008394 182.0
CSH3_k127_1490123_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 420.0
CSH3_k127_1490123_1 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001557 245.0
CSH3_k127_1509386_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 5.867e-240 763.0
CSH3_k127_1509386_1 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 486.0
CSH3_k127_1509386_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 477.0
CSH3_k127_1509386_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 333.0
CSH3_k127_1509386_4 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000004955 243.0
CSH3_k127_1509386_5 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.0004317 43.0
CSH3_k127_1526001_0 HsdM N-terminal domain K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000005403 246.0
CSH3_k127_1526001_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000000000002538 233.0
CSH3_k127_1526001_2 HsdM N-terminal domain K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000001108 217.0
CSH3_k127_1526001_3 - - - - 0.0000000000000000000000000000000000000000000000001385 181.0
CSH3_k127_1526001_4 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.00000000000000000000000008426 109.0
CSH3_k127_1526001_5 type III restriction protein res subunit K01153 - 3.1.21.3 0.00000000000000000000001392 102.0
CSH3_k127_1526001_6 structural constituent of ribosome K02924 - - 0.00000000000008283 72.0
CSH3_k127_1526001_7 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000068 71.0
CSH3_k127_1606543_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 442.0
CSH3_k127_1606543_1 Ca2 Na antiporter K07301 - - 0.0000000000007132 74.0
CSH3_k127_1608143_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 569.0
CSH3_k127_1608143_1 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 366.0
CSH3_k127_1608143_2 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.000000000003369 68.0
CSH3_k127_1651879_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.617e-217 681.0
CSH3_k127_1651879_1 DNA polymerase beta domain protein region K09717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003542 252.0
CSH3_k127_1651879_2 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000000000000000001865 160.0
CSH3_k127_1651879_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000000000000004099 107.0
CSH3_k127_1651879_4 - - - - 0.000000000002294 75.0
CSH3_k127_1651879_5 EamA-like transporter family - - - 0.00001182 53.0
CSH3_k127_165862_0 Belongs to the peptidase S16 family K06870 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001407 273.0
CSH3_k127_1674586_0 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000005071 250.0
CSH3_k127_1674586_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000004393 198.0
CSH3_k127_1674586_2 - - - - 0.00000000000000000000000000000003224 129.0
CSH3_k127_1676911_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000004636 149.0
CSH3_k127_1676911_1 Putative Fe-S cluster - - - 0.00000000000001597 78.0
CSH3_k127_1676911_2 PFAM DNA polymerase beta domain protein region - - - 0.000000002826 63.0
CSH3_k127_1676911_3 Protein of unknown function DUF86 - - - 0.0000001917 56.0
CSH3_k127_1692310_0 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000736 192.0
CSH3_k127_1692310_1 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000002556 185.0
CSH3_k127_1692310_2 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000004171 179.0
CSH3_k127_1692310_3 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000003296 170.0
CSH3_k127_1709698_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.365e-279 874.0
CSH3_k127_1709698_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000009007 109.0
CSH3_k127_1741167_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 400.0
CSH3_k127_1741167_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
CSH3_k127_1741167_2 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000002488 156.0
CSH3_k127_1741167_3 - - - - 0.0004736 42.0
CSH3_k127_1755824_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 399.0
CSH3_k127_1755824_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 339.0
CSH3_k127_1755824_2 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 304.0
CSH3_k127_1755824_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 294.0
CSH3_k127_1755824_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000000002667 190.0
CSH3_k127_1755824_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000007367 154.0
CSH3_k127_1755824_6 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000002955 85.0
CSH3_k127_1755824_7 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000009011 85.0
CSH3_k127_1755824_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000002315 85.0
CSH3_k127_1770123_0 Radical SAM ThiC family K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 520.0
CSH3_k127_1770123_1 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 461.0
CSH3_k127_1770123_2 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 310.0
CSH3_k127_1770123_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
CSH3_k127_1770123_4 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) K19091 GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0034641,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000002728 78.0
CSH3_k127_1770123_5 TIGRFAM F420-dependent oxidoreductase - - - 0.0000001956 54.0
CSH3_k127_1782953_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 580.0
CSH3_k127_1782953_1 - - - - 0.0000000000000000000000000000000000000000000000000001408 190.0
CSH3_k127_1782953_2 to GB L77117 SP Q58031 PID 1591324 percent identity - - - 0.0000000000000000000000000000000000000000000152 164.0
CSH3_k127_1793070_0 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 362.0
CSH3_k127_1793070_1 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002398 289.0
CSH3_k127_1793070_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000003962 238.0
CSH3_k127_1793070_3 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000000004689 203.0
CSH3_k127_1793070_4 Protein of unknown function (DUF2551) - - - 0.000001104 50.0
CSH3_k127_1801444_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 482.0
CSH3_k127_1801444_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000001303 120.0
CSH3_k127_1801444_2 PFAM transposase IS116 IS110 IS902 - - - 0.000000000000000006146 85.0
CSH3_k127_1801444_3 Transposase IS116/IS110/IS902 family - - - 0.0002378 45.0
CSH3_k127_1801444_4 Cytochrome C biogenesis protein transmembrane region - - - 0.000799 49.0
CSH3_k127_1848244_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 465.0
CSH3_k127_1848244_1 - K06864 - - 0.00000000000000000004171 93.0
CSH3_k127_1848244_2 - - - - 0.000000000000000005493 87.0
CSH3_k127_1848244_3 Methanogenesis marker protein 8 - - - 0.00000000002966 64.0
CSH3_k127_1857616_0 Belongs to the RtcB family K14415 - 6.5.1.3 3.068e-225 706.0
CSH3_k127_1857616_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 511.0
CSH3_k127_1857616_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000009532 250.0
CSH3_k127_1857616_3 protein conserved in archaea - - - 0.00000000000000000007464 92.0
CSH3_k127_186576_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 468.0
CSH3_k127_186576_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 376.0
CSH3_k127_186576_2 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001799 261.0
CSH3_k127_186809_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 328.0
CSH3_k127_186809_1 Citrate transporter - - - 0.00000000000000000000000000000009827 129.0
CSH3_k127_186809_2 metal ion transport K14445 - - 0.000000000000004192 75.0
CSH3_k127_1904027_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 470.0
CSH3_k127_1904027_1 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000002666 141.0
CSH3_k127_1904027_2 - - - - 0.00000000000000000000001136 104.0
CSH3_k127_1904027_3 - - - - 0.000000000000000000001912 97.0
CSH3_k127_1910914_0 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 558.0
CSH3_k127_1910914_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 483.0
CSH3_k127_1910914_2 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 359.0
CSH3_k127_1910914_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000001408 146.0
CSH3_k127_1910914_4 metal ion binding - - - 0.000000000000000000000000000001511 125.0
CSH3_k127_1910914_5 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000000008367 119.0
CSH3_k127_1910914_6 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000002507 102.0
CSH3_k127_1937216_0 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 554.0
CSH3_k127_1962776_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 454.0
CSH3_k127_1962776_1 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 397.0
CSH3_k127_1962776_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000001568 160.0
CSH3_k127_1962776_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00583 - 2.1.1.86 0.000000001473 61.0
CSH3_k127_2019671_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 567.0
CSH3_k127_2019671_1 TRAM domain - - - 0.0000000000000000002184 88.0
CSH3_k127_2028175_0 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 483.0
CSH3_k127_2028175_1 Protein of unknown function (DUF98) - - - 0.00000000000000000000000000000000000009567 144.0
CSH3_k127_2028175_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.00000000000000000000000000000000001375 138.0
CSH3_k127_2028175_3 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000002466 137.0
CSH3_k127_205213_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 317.0
CSH3_k127_205213_1 pfam ammecr1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000003091 216.0
CSH3_k127_205213_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000888 169.0
CSH3_k127_205213_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000006775 166.0
CSH3_k127_205213_4 Radical SAM domain protein - - - 0.0000000000000000000000000000000000004355 141.0
CSH3_k127_205213_5 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000001873 130.0
CSH3_k127_205213_6 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000001429 83.0
CSH3_k127_2063354_0 PFAM ABC transporter K00400 - - 5.936e-236 740.0
CSH3_k127_2063354_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 1.824e-201 634.0
CSH3_k127_2063354_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 1.715e-195 617.0
CSH3_k127_2063354_3 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 505.0
CSH3_k127_2063354_4 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 387.0
CSH3_k127_2063354_5 methanogenesis marker protein 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 385.0
CSH3_k127_2063354_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 332.0
CSH3_k127_2063354_7 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.000000000000000000000000000000000000000000000000000000000003791 211.0
CSH3_k127_2063354_8 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000009883 147.0
CSH3_k127_2063354_9 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000000000000000002427 139.0
CSH3_k127_2146760_0 Phosphoadenosine phosphosulfate reductase family K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 360.0
CSH3_k127_2146760_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 266.0
CSH3_k127_2163395_0 ATPase, AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 295.0
CSH3_k127_2163395_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000004638 107.0
CSH3_k127_2163395_2 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000001755 103.0
CSH3_k127_2163395_3 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.000267 45.0
CSH3_k127_2212698_0 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000651 262.0
CSH3_k127_2212698_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001765 239.0
CSH3_k127_2212698_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000000002685 234.0
CSH3_k127_2212698_3 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000001965 219.0
CSH3_k127_2212698_4 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000002367 198.0
CSH3_k127_2214634_0 acid binding OB-fold tRNA helicase-type K07463 - - 2.604e-272 854.0
CSH3_k127_2214634_1 nuclease K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 411.0
CSH3_k127_2214634_2 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000883 85.0
CSH3_k127_2219476_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 494.0
CSH3_k127_2219476_1 nucleic acid binding OB-fold tRNA helicase-type - - - 0.00000000000001078 78.0
CSH3_k127_2219476_2 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.0000000002902 61.0
CSH3_k127_2248498_0 Alpha beta hydrolase K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 417.0
CSH3_k127_2248498_1 hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000003604 246.0
CSH3_k127_2248498_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000002144 175.0
CSH3_k127_2254248_0 ATPases associated with a variety of cellular activities K00400 - - 1.414e-197 631.0
CSH3_k127_2254248_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 342.0
CSH3_k127_2254248_2 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007094 258.0
CSH3_k127_2254248_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001206 157.0
CSH3_k127_2254248_4 - - - - 0.000000000000000001787 87.0
CSH3_k127_2255732_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 366.0
CSH3_k127_2255732_1 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006137 280.0
CSH3_k127_2255732_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000000000000000000000005285 126.0
CSH3_k127_2255732_3 Phosphate transport regulator K07220 - - 0.000000000000000000000589 96.0
CSH3_k127_2277314_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 307.0
CSH3_k127_2277314_1 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000004581 186.0
CSH3_k127_2277314_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000001435 132.0
CSH3_k127_2277314_3 Iron-sulphur cluster biosynthesis K15724 - - 0.0000000000000000000000000005107 116.0
CSH3_k127_2277314_4 Protein of unknown function (DUF2551) - - - 0.000000000000000000008151 95.0
CSH3_k127_2284752_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 535.0
CSH3_k127_2284752_1 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 344.0
CSH3_k127_2284752_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001108 285.0
CSH3_k127_2284752_3 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002342 251.0
CSH3_k127_2284752_4 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000005561 78.0
CSH3_k127_228496_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001835 282.0
CSH3_k127_228496_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000003712 134.0
CSH3_k127_228496_2 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.0000000000000003463 79.0
CSH3_k127_228496_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000009091 61.0
CSH3_k127_228496_4 HEPN domain - - - 0.000000001634 68.0
CSH3_k127_228496_5 Nucleotidyltransferase domain K07076 - - 0.0000005964 60.0
CSH3_k127_2311465_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.198e-299 931.0
CSH3_k127_2311465_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 309.0
CSH3_k127_2311465_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000003946 214.0
CSH3_k127_2311465_3 Belongs to the sulfur carrier protein TusA family - - - 0.000000001551 61.0
CSH3_k127_2323028_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 295.0
CSH3_k127_2323028_1 PFAM TfuA domain protein, core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
CSH3_k127_2324481_0 Peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 463.0
CSH3_k127_2324481_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000004242 125.0
CSH3_k127_2324481_2 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000007793 105.0
CSH3_k127_233874_0 phosphoesterase RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 399.0
CSH3_k127_233874_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000007519 144.0
CSH3_k127_2340906_0 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 455.0
CSH3_k127_2340906_1 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 344.0
CSH3_k127_2340906_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000008244 69.0
CSH3_k127_2340906_3 peptidase M42 family protein - - - 0.0000000007448 61.0
CSH3_k127_2365097_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 5.333e-263 825.0
CSH3_k127_2405164_0 COG0464 ATPases of the AAA class K13525 - - 1.008e-278 875.0
CSH3_k127_2405164_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 517.0
CSH3_k127_2405164_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000001838 182.0
CSH3_k127_2405164_3 PFAM PRC-barrel domain - - - 0.0000000000000000000001105 99.0
CSH3_k127_2405164_4 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000002782 89.0
CSH3_k127_2405164_5 - - - - 0.0000000004143 67.0
CSH3_k127_2405164_6 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000008595 55.0
CSH3_k127_2446723_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 426.0
CSH3_k127_2446723_1 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 340.0
CSH3_k127_2446723_2 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 295.0
CSH3_k127_2446723_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000004758 102.0
CSH3_k127_2463252_0 Radical SAM K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 523.0
CSH3_k127_2463252_1 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000000000000000000000000000001356 186.0
CSH3_k127_2463252_2 CoA binding domain K06929 - - 0.00000000000000000000000000000000000001806 147.0
CSH3_k127_2463252_3 TIGRFAM type I restriction system adenine methylase (hsdM) K03427 - 2.1.1.72 0.00000000000006973 72.0
CSH3_k127_2469930_0 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000003033 229.0
CSH3_k127_2469930_1 PFAM Phosphatidylglycerophosphatase A - - - 0.000000000000000000000000000000000000000000000000000000000000253 216.0
CSH3_k127_2469930_2 PFAM HhH-GPD family protein K03575 - - 0.000000000002172 72.0
CSH3_k127_2469930_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000002727 63.0
CSH3_k127_2472204_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 1.662e-226 718.0
CSH3_k127_2472204_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 3.987e-206 650.0
CSH3_k127_2472204_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
CSH3_k127_2472204_3 COG1138 Cytochrome c biogenesis factor K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
CSH3_k127_2472204_4 KEOPS complex Cgi121-like subunit K09119 - - 0.000000000000000000000000000000000004191 142.0
CSH3_k127_2472204_5 Transposase DDE domain K07495 - - 0.0000001465 53.0
CSH3_k127_248412_0 TIGRFAM UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 546.0
CSH3_k127_248412_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000002725 257.0
CSH3_k127_248412_2 TGS domain protein K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005587 255.0
CSH3_k127_248412_3 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000006889 93.0
CSH3_k127_248412_4 Protein of unknown function (DUF2283) - - - 0.00000000346 61.0
CSH3_k127_2507245_0 PFAM Aldehyde dehydrogenase K22187 - - 6.191e-202 635.0
CSH3_k127_2507245_1 Aminotransferase class-III K00823,K00836 - 2.6.1.19,2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 534.0
CSH3_k127_2507245_2 Belongs to the peptidase S16 family K06870 - - 0.0000000000000000002845 97.0
CSH3_k127_2528323_0 Domain of unknown function K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 277.0
CSH3_k127_2528323_1 Putative zincin peptidase - - - 0.0000000002854 69.0
CSH3_k127_258034_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 588.0
CSH3_k127_258034_1 SMART Elongator protein 3 MiaB NifB K06935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
CSH3_k127_258034_2 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000001286 177.0
CSH3_k127_2637781_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000007918 225.0
CSH3_k127_2637781_1 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000003844 123.0
CSH3_k127_2668737_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 4.107e-202 636.0
CSH3_k127_2668737_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 319.0
CSH3_k127_2668737_2 - - - - 0.0001021 52.0
CSH3_k127_2684820_0 KH, type 1, domain K07041 - - 1.039e-289 898.0
CSH3_k127_2684820_1 GDP dissociation inhibitor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 574.0
CSH3_k127_2684820_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 295.0
CSH3_k127_2684820_3 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000001356 208.0
CSH3_k127_2684820_4 Xylose isomerase-like TIM barrel - - - 0.00002409 48.0
CSH3_k127_272569_0 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 449.0
CSH3_k127_272569_1 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001076 267.0
CSH3_k127_2755738_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 368.0
CSH3_k127_2755738_1 - - - - 0.00006153 53.0
CSH3_k127_2821810_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 469.0
CSH3_k127_2821810_1 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000004755 156.0
CSH3_k127_2821810_2 Membrane protein of unknown function DUF63 - - - 0.0000000000000000000000000000000000002249 146.0
CSH3_k127_2821810_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000001738 137.0
CSH3_k127_282665_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 479.0
CSH3_k127_282665_1 methyltransferase activity - - - 0.00000000000000000000000000000000000000000206 158.0
CSH3_k127_2842870_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 420.0
CSH3_k127_2842870_1 in RNase L inhibitor, RLI K06174 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 304.0
CSH3_k127_2842870_2 RNase L inhibitor, RLI - - - 0.000000000000000009027 91.0
CSH3_k127_28480_0 Protein of unknown function (DUF460) K09150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 575.0
CSH3_k127_28480_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002247 265.0
CSH3_k127_28480_2 hydrolase K04794 - 3.1.1.29 0.000000000000000000000000000000000000000000000001373 175.0
CSH3_k127_28480_3 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000003663 67.0
CSH3_k127_28480_4 - - - - 0.0000001217 57.0
CSH3_k127_2871630_0 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 526.0
CSH3_k127_2871630_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 426.0
CSH3_k127_2871630_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000001204 179.0
CSH3_k127_2871630_3 Radical SAM domain protein K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000003036 173.0
CSH3_k127_2871630_4 Transposase DDE domain K07495 - - 0.0000000001101 63.0
CSH3_k127_287765_0 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 452.0
CSH3_k127_287765_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 320.0
CSH3_k127_287765_2 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.0000000000000000000000000000008052 123.0
CSH3_k127_2878771_0 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000001258 147.0
CSH3_k127_2878771_1 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000002466 125.0
CSH3_k127_2878771_2 Nucleotidyltransferase domain K07075 - - 0.00000002709 57.0
CSH3_k127_2883729_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.816e-251 787.0
CSH3_k127_2883729_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000006977 239.0
CSH3_k127_2883729_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000001277 176.0
CSH3_k127_2883729_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000004715 117.0
CSH3_k127_2883729_4 Binds to the 23S rRNA K02896 - - 0.000000000000000000000001165 104.0
CSH3_k127_2883729_5 - - - - 0.0000000000009604 77.0
CSH3_k127_2889157_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 464.0
CSH3_k127_2889157_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001666 280.0
CSH3_k127_2889157_2 Fe-S cluster K04488 - - 0.00000000000000000000000000000000000000000000000000000000002859 208.0
CSH3_k127_2889157_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000001049 64.0
CSH3_k127_2962235_0 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000009548 213.0
CSH3_k127_2962235_1 PFAM Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000002524 177.0
CSH3_k127_2962235_2 PFAM Cation K03498 - - 0.0000000000000000001819 89.0
CSH3_k127_2996184_0 HMGL-like K01649 - 2.3.3.13 1.994e-206 649.0
CSH3_k127_2996184_1 protein conserved in archaea - - - 0.000000000000000000000000000000000000001174 160.0
CSH3_k127_2996184_2 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000001062 75.0
CSH3_k127_3024269_0 PFAM ubiE COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000008752 151.0
CSH3_k127_3024269_1 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.0000000000000000000000004197 110.0
CSH3_k127_3024269_2 membrane protein (DUF2078) K08982 - - 0.00000000001205 67.0
CSH3_k127_3054173_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000001168 192.0
CSH3_k127_3054173_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000001076 160.0
CSH3_k127_3054173_2 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000004612 124.0
CSH3_k127_3066407_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 437.0
CSH3_k127_3066407_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 410.0
CSH3_k127_3066407_2 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003434 255.0
CSH3_k127_3066407_3 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000006586 243.0
CSH3_k127_3066407_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000001551 172.0
CSH3_k127_3066407_5 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000005398 160.0
CSH3_k127_3066407_6 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000004881 75.0
CSH3_k127_3098104_0 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 544.0
CSH3_k127_3098104_1 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 313.0
CSH3_k127_3098104_2 Methyl-coenzyme M reductase operon protein D K03422 - - 0.000000000000000000000000000000000008741 141.0
CSH3_k127_3098104_3 adenyl ribonucleotide binding - - - 0.00000000000000000000000007456 111.0
CSH3_k127_3098104_4 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.000000003026 61.0
CSH3_k127_309907_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 8.991e-230 724.0
CSH3_k127_309907_1 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 373.0
CSH3_k127_309907_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 355.0
CSH3_k127_309907_3 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 258.0
CSH3_k127_3122200_0 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 459.0
CSH3_k127_3122200_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000001293 198.0
CSH3_k127_3122200_2 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000004493 175.0
CSH3_k127_3122200_3 - - - - 0.0000000000000313 77.0
CSH3_k127_3122200_4 - - - - 0.00000000000008041 72.0
CSH3_k127_3149671_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 463.0
CSH3_k127_3149671_1 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000003504 227.0
CSH3_k127_3149671_2 Family of unknown function (DUF5371) - - - 0.00000000000000001377 83.0
CSH3_k127_3149671_3 Uncharacterized metal-binding protein (DUF2227) - - - 0.00000000001892 67.0
CSH3_k127_3173784_0 Psort location Cytoplasmic, score K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 523.0
CSH3_k127_3173784_1 Domain of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000009731 229.0
CSH3_k127_3173784_2 (Rhomboid) family - - - 0.000000000008322 71.0
CSH3_k127_3189829_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 7.969e-305 948.0
CSH3_k127_3189829_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 439.0
CSH3_k127_3189829_2 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 347.0
CSH3_k127_3189829_3 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000002274 221.0
CSH3_k127_3189829_4 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000000000000007685 150.0
CSH3_k127_3189829_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 - - - 0.00000000000000000000001622 106.0
CSH3_k127_3189829_6 transcriptional K07729 - - 0.0000000000000000000001419 102.0
CSH3_k127_3201853_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 505.0
CSH3_k127_3201853_1 PFAM AIR synthase related protein K07388 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 385.0
CSH3_k127_3235552_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.894e-195 615.0
CSH3_k127_3235552_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.291e-195 612.0
CSH3_k127_3235552_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 424.0
CSH3_k127_3235552_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004404 271.0
CSH3_k127_3235552_4 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007532 243.0
CSH3_k127_3235552_5 DUF35 OB-fold domain, acyl-CoA-associated K07068,K07549 - - 0.000000000000000000001933 98.0
CSH3_k127_3235552_6 - - - - 0.00000001946 57.0
CSH3_k127_3242069_0 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 330.0
CSH3_k127_3242069_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 311.0
CSH3_k127_3242069_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000008475 241.0
CSH3_k127_3242069_3 carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000000000002448 181.0
CSH3_k127_3242069_4 - - - - 0.000000000000000000000000003871 114.0
CSH3_k127_3296196_0 Mn2 dependent serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 421.0
CSH3_k127_3296196_1 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000004572 234.0
CSH3_k127_3324715_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 352.0
CSH3_k127_3324715_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 324.0
CSH3_k127_3324715_2 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 294.0
CSH3_k127_3324715_3 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000001978 198.0
CSH3_k127_3329100_0 Type II/IV secretion system protein - - - 2.497e-202 651.0
CSH3_k127_3329100_1 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000003146 184.0
CSH3_k127_3334310_0 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001636 249.0
CSH3_k127_3334310_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000001078 231.0
CSH3_k127_3334310_2 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000004631 203.0
CSH3_k127_3354554_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005382 286.0
CSH3_k127_3354554_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 261.0
CSH3_k127_3354554_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001523 234.0
CSH3_k127_3407958_0 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 467.0
CSH3_k127_3407958_1 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000253 143.0
CSH3_k127_3427660_0 DEAD DEAH box helicase domain protein K03724 - - 3.315e-235 740.0
CSH3_k127_3427660_1 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 366.0
CSH3_k127_3427660_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 346.0
CSH3_k127_3427660_3 Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000541 157.0
CSH3_k127_3427660_4 PFAM phosphatidate cytidylyltransferase - - - 0.000000000000000000000000000000001739 136.0
CSH3_k127_3427660_5 - - - - 0.0000000000000004969 83.0
CSH3_k127_3430350_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 1.458e-242 758.0
CSH3_k127_3430350_1 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 381.0
CSH3_k127_3430350_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 312.0
CSH3_k127_3430350_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 293.0
CSH3_k127_3430350_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000004754 88.0
CSH3_k127_3469700_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.169e-200 634.0
CSH3_k127_3469700_1 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 403.0
CSH3_k127_3469700_2 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 396.0
CSH3_k127_3469700_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000005426 215.0
CSH3_k127_3469700_4 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000006665 183.0
CSH3_k127_3495156_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 358.0
CSH3_k127_350978_0 Necessary for normal cell division and for the maintenance of normal septation - - - 0.000000000000000000000000000000000000000000000000000000000000000001806 231.0
CSH3_k127_350978_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000005219 178.0
CSH3_k127_350978_2 nuclease activity - - - 0.000000000000000003075 87.0
CSH3_k127_350978_3 HEAT repeats - - - 0.0000000000000005699 86.0
CSH3_k127_3510576_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 608.0
CSH3_k127_3518666_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 460.0
CSH3_k127_3518666_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000001657 240.0
CSH3_k127_3518666_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000001689 122.0
CSH3_k127_3518666_3 - - - - 0.000000000000001592 79.0
CSH3_k127_3518666_4 Putative zinc- or iron-chelating domain K06940 - - 0.0000000004215 68.0
CSH3_k127_3530_0 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000004312 115.0
CSH3_k127_3530_1 - - - - 0.0000000000000000000000005071 114.0
CSH3_k127_3530_2 Fic/DOC family - - - 0.0000000008166 61.0
CSH3_k127_3534022_0 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000001306 222.0
CSH3_k127_3534022_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000001888 172.0
CSH3_k127_3534022_2 PIN domain - - - 0.000000000000000000000000000000002686 134.0
CSH3_k127_3534022_3 - - - - 0.0001109 47.0
CSH3_k127_3534134_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 417.0
CSH3_k127_3534134_1 abc transporter atp-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000557 237.0
CSH3_k127_3534134_2 domain protein K01992 - - 0.0001502 50.0
CSH3_k127_3554526_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1073.0
CSH3_k127_3554526_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 9.221e-216 674.0
CSH3_k127_3554526_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 318.0
CSH3_k127_3554526_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.0000000000000000000000000000000000000000000004973 173.0
CSH3_k127_3554526_4 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000002589 117.0
CSH3_k127_3554526_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000007082 63.0
CSH3_k127_3554526_6 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0001056 46.0
CSH3_k127_356488_0 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 393.0
CSH3_k127_356488_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000433 261.0
CSH3_k127_356488_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000001862 140.0
CSH3_k127_356488_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000002332 116.0
CSH3_k127_356488_4 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000004844 79.0
CSH3_k127_357854_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 379.0
CSH3_k127_357854_1 Domain of unknown function (DUF362) K07138 - - 0.0000000000000000000000000000000001542 134.0
CSH3_k127_3581288_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 610.0
CSH3_k127_3581288_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 298.0
CSH3_k127_3581288_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000004446 143.0
CSH3_k127_3581288_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00001183 49.0
CSH3_k127_3596538_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 424.0
CSH3_k127_3596538_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000003689 215.0
CSH3_k127_3600607_0 ATP-grasp domain K06914 - 6.3.4.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 288.0
CSH3_k127_3600607_1 - - - - 0.0000000000000000000000000000000000000005751 153.0
CSH3_k127_3600607_2 - - - - 0.000000000000000000000852 109.0
CSH3_k127_3600607_3 - - - - 0.00000000000008337 79.0
CSH3_k127_3604931_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000001203 224.0
CSH3_k127_3610207_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 602.0
CSH3_k127_3610207_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 355.0
CSH3_k127_3610207_2 inter-alpha-trypsin inhibitor heavy chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004285 276.0
CSH3_k127_3610207_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162 - 1.2.4.1 0.00000000000000000005697 91.0
CSH3_k127_3610207_4 Belongs to the UPF0248 family K09715 - - 0.000000000008959 68.0
CSH3_k127_3670036_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.166e-232 728.0
CSH3_k127_3702545_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 463.0
CSH3_k127_3702545_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 428.0
CSH3_k127_3702545_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000008619 243.0
CSH3_k127_3702545_3 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000459 198.0
CSH3_k127_3702545_4 RuvA, C-terminal domain K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000001624 189.0
CSH3_k127_3709062_0 Thermolysin metallopeptidase, alpha-helical domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 383.0
CSH3_k127_3709062_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 376.0
CSH3_k127_3709062_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 385.0
CSH3_k127_3709062_3 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000000000001536 219.0
CSH3_k127_3709062_4 - - - - 0.00000000000000000000005259 103.0
CSH3_k127_3709062_5 Peptidase M4 - - - 0.0000001183 56.0
CSH3_k127_3709247_0 Pfam:Methyltransf_26 - - - 0.00000000000000000000000000000000000000000000000000000000000000008601 243.0
CSH3_k127_3712267_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 377.0
CSH3_k127_3712267_1 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 287.0
CSH3_k127_3720583_0 Has ATPase and non-specific DNA-binding activities K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 594.0
CSH3_k127_3720583_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 489.0
CSH3_k127_3720583_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 302.0
CSH3_k127_3720583_3 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001037 288.0
CSH3_k127_3720583_4 Protein of unknown function (DUF3772) K05802 - - 0.000000000000005844 85.0
CSH3_k127_3720583_5 PFAM Transposase IS200 like K07491 - - 0.0000001493 54.0
CSH3_k127_3735361_0 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007011 280.0
CSH3_k127_3735361_1 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000892 247.0
CSH3_k127_3735361_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000002755 179.0
CSH3_k127_3741541_0 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 312.0
CSH3_k127_3741541_1 - - - - 0.000026 53.0
CSH3_k127_3748702_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 443.0
CSH3_k127_3748702_1 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000601 228.0
CSH3_k127_3748702_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000005278 203.0
CSH3_k127_3748702_3 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000003494 185.0
CSH3_k127_3748702_4 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.000000000000000000000000000000000009939 139.0
CSH3_k127_3748702_5 membrane - - - 0.000000000000000000005813 100.0
CSH3_k127_3748702_6 Uncharacterised ArCR, COG2043 - - - 0.000000000000001599 77.0
CSH3_k127_3755252_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004021 284.0
CSH3_k127_3755252_1 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.000000000000001653 77.0
CSH3_k127_3759793_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.848e-212 666.0
CSH3_k127_3759793_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 5.275e-204 641.0
CSH3_k127_3759793_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000005898 179.0
CSH3_k127_3759793_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000005144 93.0
CSH3_k127_3759793_4 zinc finger - - - 0.0000000000000002821 80.0
CSH3_k127_3759793_5 - - - - 0.0000000000001255 72.0
CSH3_k127_3795662_0 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 506.0
CSH3_k127_3795662_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 394.0
CSH3_k127_3795662_2 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 372.0
CSH3_k127_3795662_3 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 303.0
CSH3_k127_3795662_4 - - - - 0.000000000000005914 78.0
CSH3_k127_3795662_5 Dodecin K09165 - - 0.00007302 46.0
CSH3_k127_3797439_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 552.0
CSH3_k127_3797439_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000004258 59.0
CSH3_k127_3810226_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 518.0
CSH3_k127_3810226_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000001722 123.0
CSH3_k127_3810226_2 integral membrane protein K07027 - - 0.00000000000000004406 92.0
CSH3_k127_3857443_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 540.0
CSH3_k127_3857443_1 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 407.0
CSH3_k127_3857443_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000002328 249.0
CSH3_k127_3870156_0 PFAM AIR synthase related protein K07123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 458.0
CSH3_k127_3870156_1 radical SAM domain protein K22226 - - 0.0000000000000000000000000000000000000000000000000005025 184.0
CSH3_k127_3870156_2 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000005022 162.0
CSH3_k127_3870156_3 Pfam:UPF0118 - - - 0.000000000000000000009675 93.0
CSH3_k127_3897268_0 COG0785 Cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000348 149.0
CSH3_k127_3897268_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000001119 76.0
CSH3_k127_3897268_2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone - - - 0.0000001466 53.0
CSH3_k127_3897268_3 Protein of unknown function with PCYCGC motif - - - 0.000005492 49.0
CSH3_k127_3901288_0 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 332.0
CSH3_k127_3901288_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000001348 204.0
CSH3_k127_3901288_2 PFAM Cupin domain - - - 0.00000000000000000000000004137 109.0
CSH3_k127_3925465_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 601.0
CSH3_k127_3925465_1 Uncharacterised protein family UPF0058 - - - 0.00000000000000000001932 92.0
CSH3_k127_395359_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0000000000000000000000000000000000000000000000000000000000000000000000003394 254.0
CSH3_k127_395359_1 DNA methylase K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000003275 192.0
CSH3_k127_395359_2 PFAM DNA polymerase beta domain protein region K07076 - - 0.000000000000000000000000001068 118.0
CSH3_k127_395359_3 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.000000005697 61.0
CSH3_k127_3954320_0 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 485.0
CSH3_k127_399631_0 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
CSH3_k127_399631_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001217 247.0
CSH3_k127_399631_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000002203 231.0
CSH3_k127_399631_3 AN1-like Zinc finger K07059 - - 0.0000000004693 61.0
CSH3_k127_4015790_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 327.0
CSH3_k127_4015790_1 - - - - 0.000000000000000000000000000000000000000000000003319 176.0
CSH3_k127_4015790_2 AAA domain K07133 - - 0.000000000000000000000000002314 116.0
CSH3_k127_4015790_3 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000001411 56.0
CSH3_k127_4033218_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.008e-228 724.0
CSH3_k127_4033218_1 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 9.345e-208 653.0
CSH3_k127_4033218_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 611.0
CSH3_k127_4044141_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 1.719e-219 694.0
CSH3_k127_4044141_1 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 343.0
CSH3_k127_4044141_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000003717 166.0
CSH3_k127_4044141_3 HEPN domain - - - 0.000000000000000008327 85.0
CSH3_k127_4044446_0 AAA family ATPase, CDC48 subfamily K13525 - - 1.424e-318 990.0
CSH3_k127_4044446_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 603.0
CSH3_k127_4044446_2 Transposase IS200 like K07491 - - 0.0000004965 54.0
CSH3_k127_4076804_0 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 416.0
CSH3_k127_4076804_1 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000001325 220.0
CSH3_k127_4076804_2 - - - - 0.00000000000000000000000000000000001768 141.0
CSH3_k127_412102_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 499.0
CSH3_k127_412102_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 305.0
CSH3_k127_412102_2 Major facilitator superfamily K19576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003253 255.0
CSH3_k127_412102_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000001213 170.0
CSH3_k127_412102_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000002451 115.0
CSH3_k127_412102_5 - - - - 0.000000000000000006347 86.0
CSH3_k127_4128262_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 455.0
CSH3_k127_4128262_1 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000005145 80.0
CSH3_k127_4128262_2 PFAM malic K00027 - 1.1.1.38 0.0001278 45.0
CSH3_k127_4129620_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 583.0
CSH3_k127_4129620_1 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000001303 220.0
CSH3_k127_4129620_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000007723 146.0
CSH3_k127_4156131_0 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 505.0
CSH3_k127_4156131_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 307.0
CSH3_k127_4156131_2 Non-histone chromosomal protein MC1 - - - 0.00000000000000000000000000000000000000000005041 162.0
CSH3_k127_4156131_3 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000005094 115.0
CSH3_k127_4156131_4 Rhodanese Homology Domain - - - 0.000000000000000003471 87.0
CSH3_k127_4156131_5 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000003083 65.0
CSH3_k127_4158480_0 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 423.0
CSH3_k127_4158480_1 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000119 129.0
CSH3_k127_4158480_2 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000001163 94.0
CSH3_k127_4158480_3 PFAM PP-loop domain protein K06864 - - 0.000001149 50.0
CSH3_k127_416391_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 4.47e-220 689.0
CSH3_k127_416391_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 456.0
CSH3_k127_416391_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 373.0
CSH3_k127_416391_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 338.0
CSH3_k127_416391_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 304.0
CSH3_k127_416391_5 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000000008235 239.0
CSH3_k127_4175124_0 DHH family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 397.0
CSH3_k127_4175124_1 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 383.0
CSH3_k127_4175124_2 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001801 265.0
CSH3_k127_4175124_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000000000000001048 130.0
CSH3_k127_4175124_4 Transcription factor Pcc1 K09741 - - 0.000000006378 60.0
CSH3_k127_4181046_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 323.0
CSH3_k127_4181046_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002673 271.0
CSH3_k127_4181046_2 Mediates influx of magnesium ions - - - 0.00000000000000000000000000000000000000000000000001491 198.0
CSH3_k127_4181046_3 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000004948 98.0
CSH3_k127_4181046_4 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00009277 45.0
CSH3_k127_4181046_5 COG1361 S-layer domain - - - 0.0001251 54.0
CSH3_k127_4228727_0 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000004192 237.0
CSH3_k127_4228727_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000002338 192.0
CSH3_k127_4228727_2 structural constituent of ribosome K02962 - - 0.000000000000006771 77.0
CSH3_k127_4229256_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.241e-204 649.0
CSH3_k127_4229256_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 454.0
CSH3_k127_4229256_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000003066 179.0
CSH3_k127_4229256_3 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.00000000000000000000000000000000003825 136.0
CSH3_k127_4229256_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000005141 97.0
CSH3_k127_4229256_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000002393 95.0
CSH3_k127_4229256_6 PFAM CO dehydrogenase beta subunit acetyl-CoA synthase epsilon subunit K00195,K03800 - 6.3.1.20 0.000000000000000000003223 103.0
CSH3_k127_4320596_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000009716 246.0
CSH3_k127_4320596_1 archaeal Zn-finger protein - - - 0.00000000000000000000000000000132 128.0
CSH3_k127_4320596_2 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.0000000000009891 71.0
CSH3_k127_4332049_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 9.183e-271 847.0
CSH3_k127_4332049_1 FMN binding - - - 6.127e-259 806.0
CSH3_k127_4332049_2 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 285.0
CSH3_k127_4332049_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000001715 169.0
CSH3_k127_4332049_4 PFAM ferredoxin-dependent glutamate synthase - - - 0.00000000000000000000000009215 107.0
CSH3_k127_4349712_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 291.0
CSH3_k127_4349712_1 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001076 247.0
CSH3_k127_4349712_2 TIGRFAM archaeoflavoprotein AfpA - - - 0.0000000000000000000000000000000000000000000000000000000002575 207.0
CSH3_k127_4349712_3 COG1522 Transcriptional regulators - - - 0.0000000000000000000000003239 107.0
CSH3_k127_4349712_4 Protein of unknown function (DUF1616) - - - 0.0000001065 54.0
CSH3_k127_4350666_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 331.0
CSH3_k127_4350666_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 322.0
CSH3_k127_4350666_2 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 286.0
CSH3_k127_4350666_3 PFAM Rubrerythrin - - - 0.0000288 53.0
CSH3_k127_437686_0 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 513.0
CSH3_k127_437686_1 Trm112p-like protein - - - 0.0000000000000000000000002681 105.0
CSH3_k127_4398307_0 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 505.0
CSH3_k127_4398307_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 404.0
CSH3_k127_4398307_2 COGs COG3316 Transposase and inactivated derivatives - - - 0.0000001135 56.0
CSH3_k127_4425124_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.827e-197 625.0
CSH3_k127_4425124_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003027 284.0
CSH3_k127_4425124_2 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000008856 124.0
CSH3_k127_4434597_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 569.0
CSH3_k127_4434597_1 eRF1 domain 2 - - - 0.0000000000000000000000000004542 120.0
CSH3_k127_4434597_2 RNA-binding protein involved in rRNA processing K07569 - - 0.000000003175 61.0
CSH3_k127_4444827_0 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 526.0
CSH3_k127_4444827_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 408.0
CSH3_k127_4444827_2 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000005507 220.0
CSH3_k127_4444827_3 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000000000000000000001345 110.0
CSH3_k127_4444827_4 F420H2 dehydrogenase subunit FpoO K22170 - 1.5.98.3 0.00000000000006612 76.0
CSH3_k127_4444827_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000054 63.0
CSH3_k127_4444827_6 - - - - 0.00000008262 57.0
CSH3_k127_4444827_7 DGC domain protein - - - 0.0000004411 55.0
CSH3_k127_4450402_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 348.0
CSH3_k127_4450402_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006958 253.0
CSH3_k127_4480353_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.056e-255 797.0
CSH3_k127_4480353_1 tRNAHis guanylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001794 257.0
CSH3_k127_4480353_2 PFAM PRC-barrel domain - - - 0.00000000000000000000000003116 111.0
CSH3_k127_4484202_0 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 455.0
CSH3_k127_4484202_1 Protein of unknown function (DUF1464) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009813 254.0
CSH3_k127_4484202_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001816 238.0
CSH3_k127_4484202_3 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000016 201.0
CSH3_k127_4484202_4 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000262 73.0
CSH3_k127_452212_0 Involved in regulation of DNA replication K10725 - - 4.263e-256 792.0
CSH3_k127_452212_1 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 286.0
CSH3_k127_452212_2 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000001011 236.0
CSH3_k127_452212_3 PFAM Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000004596 179.0
CSH3_k127_4529958_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 437.0
CSH3_k127_4529958_1 Transposase DDE domain K07487 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005267 285.0
CSH3_k127_4529958_2 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.0000000000000000000000000000001536 132.0
CSH3_k127_4565300_0 DEAD DEAH box helicase domain protein K10896 - - 2.18e-275 865.0
CSH3_k127_4565300_1 - - - - 0.0000000000000000000000000000000000000000000000000000005335 196.0
CSH3_k127_4565300_2 PIN domain - - - 0.00000000000000000000000739 103.0
CSH3_k127_4565300_3 - - - - 0.00000000116 61.0
CSH3_k127_4565300_4 Thioredoxin domain - - - 0.0000000041 61.0
CSH3_k127_4583516_0 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 368.0
CSH3_k127_4583516_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.000000000000000000000006686 103.0
CSH3_k127_4583516_2 general secretion pathway protein K02457 - - 0.0000000001211 68.0
CSH3_k127_4624405_0 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 320.0
CSH3_k127_4624405_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001552 269.0
CSH3_k127_4624405_2 PFAM transposase IS116 IS110 IS902 - - - 0.000000000004829 69.0
CSH3_k127_4657142_0 in RNase L inhibitor, RLI K06174 - - 5.462e-194 612.0
CSH3_k127_4657142_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 425.0
CSH3_k127_4659644_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.129e-243 760.0
CSH3_k127_4659644_1 phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000002218 182.0
CSH3_k127_466511_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
CSH3_k127_466511_1 Transposase - - - 0.00000000000000000000000000000000007269 137.0
CSH3_k127_466511_2 Domain of unknown function (DUF4338) - - - 0.000000000001608 74.0
CSH3_k127_466511_3 PFAM Transposase IS66 family K07484 - - 0.000000000007628 72.0
CSH3_k127_4682485_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 603.0
CSH3_k127_4682485_1 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000003801 231.0
CSH3_k127_4682485_2 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.0000001316 53.0
CSH3_k127_4687285_0 PFAM dihydropteroate synthase, DHPS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 506.0
CSH3_k127_4687285_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000594 95.0
CSH3_k127_4687285_2 MarC family integral membrane protein K05595 - - 0.0002798 43.0
CSH3_k127_4696271_0 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 423.0
CSH3_k127_4696271_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003289 222.0
CSH3_k127_47_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 600.0
CSH3_k127_47_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 457.0
CSH3_k127_47_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 450.0
CSH3_k127_47_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 414.0
CSH3_k127_47_4 V4R K07013 - - 0.0000000000000000000000000000000000000000000000000000000000000009477 228.0
CSH3_k127_47_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000009742 164.0
CSH3_k127_47_6 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000002686 135.0
CSH3_k127_47_7 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.00000000000000000002775 93.0
CSH3_k127_47_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000002506 79.0
CSH3_k127_47_9 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.00000000000006798 72.0
CSH3_k127_4704228_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 441.0
CSH3_k127_4704228_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008743,GO:0009066,GO:0009987,GO:0016043,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 362.0
CSH3_k127_470808_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 588.0
CSH3_k127_470808_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 304.0
CSH3_k127_4772827_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 396.0
CSH3_k127_4772827_1 S4 RNA-binding domain K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000005387 97.0
CSH3_k127_4776816_0 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 609.0
CSH3_k127_4776816_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 566.0
CSH3_k127_4776816_10 DsrE/DsrF-like family K07236 - - 0.00000000689 61.0
CSH3_k127_4776816_2 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 485.0
CSH3_k127_4776816_3 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 407.0
CSH3_k127_4776816_4 Involved in molybdopterin and thiamine biosynthesis, family 2 K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 316.0
CSH3_k127_4776816_5 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 303.0
CSH3_k127_4776816_6 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000005743 210.0
CSH3_k127_4776816_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000001494 189.0
CSH3_k127_4776816_8 Sulfurtransferase TusA K04085 - - 0.0000000000000000007227 89.0
CSH3_k127_4776816_9 DsrE/DsrF-like family - - - 0.00000000003777 68.0
CSH3_k127_4798939_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 319.0
CSH3_k127_4798939_1 Cupin 2, conserved barrel domain protein K00971,K01809,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000004089 171.0
CSH3_k127_4832586_0 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000002714 104.0
CSH3_k127_4832586_1 COG0464 ATPases of the AAA class K13525 - - 0.00000000003666 63.0
CSH3_k127_4856057_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.125e-285 919.0
CSH3_k127_4856057_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.276e-214 679.0
CSH3_k127_4856057_2 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000006011 174.0
CSH3_k127_4856057_3 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.00000000000000001709 85.0
CSH3_k127_4894230_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 437.0
CSH3_k127_4894230_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 379.0
CSH3_k127_4894230_2 Protein of unknown function (DUF434) - - - 0.000000000000000000000000000000000000000000661 164.0
CSH3_k127_4894230_3 - - - - 0.0000000000000000000000000000000000000001931 156.0
CSH3_k127_4894230_4 DNA methylase K07316 - 2.1.1.72 0.0000000000003344 72.0
CSH3_k127_496447_0 - - - - 0.000000000000000000000000000000000000002297 154.0
CSH3_k127_496447_1 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000009561 153.0
CSH3_k127_496447_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000003396 117.0
CSH3_k127_496447_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000001753 99.0
CSH3_k127_5002745_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 410.0
CSH3_k127_5002745_1 PFAM Appr-1-p processing - - - 0.000000000000000000000000000000000000000000000000000000000000008568 220.0
CSH3_k127_5002745_2 COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase K03179 - 2.5.1.39 0.00002242 48.0
CSH3_k127_5011974_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 557.0
CSH3_k127_5015063_0 - - - - 0.0000002137 58.0
CSH3_k127_5029097_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 452.0
CSH3_k127_5029097_1 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000001603 222.0
CSH3_k127_5029097_2 Belongs to the acylphosphatase family - - - 0.000000000000000000000000000000000000000002344 160.0
CSH3_k127_5029097_3 ThiS family K03636 - - 0.00000000000000000000302 95.0
CSH3_k127_5055002_0 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 578.0
CSH3_k127_5055002_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000001141 171.0
CSH3_k127_5055002_2 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000002159 113.0
CSH3_k127_5055002_3 - - - - 0.0000000000000003988 81.0
CSH3_k127_5078616_0 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 344.0
CSH3_k127_5078616_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001198 280.0
CSH3_k127_5078616_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001444 266.0
CSH3_k127_5078616_3 PFAM metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003196 248.0
CSH3_k127_5078616_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000001904 176.0
CSH3_k127_5078616_5 DEAD DEAH box helicase K06877 - - 0.000000000000000000003839 93.0
CSH3_k127_5082671_0 S-layer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 601.0
CSH3_k127_5082671_1 Dihydrouridine synthase (Dus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 313.0
CSH3_k127_5082671_2 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000004393 198.0
CSH3_k127_5082671_3 PFAM amine oxidase - - - 0.0000000000000000000000000000000000004615 142.0
CSH3_k127_5090807_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.344e-218 682.0
CSH3_k127_5090807_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 573.0
CSH3_k127_5090807_2 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000005507 128.0
CSH3_k127_5090807_3 Type III restriction enzyme res subunit K01156 - 3.1.21.5 0.0000000000000000002608 91.0
CSH3_k127_5090807_4 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.00000002209 60.0
CSH3_k127_5095811_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 6.714e-266 831.0
CSH3_k127_5095811_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 399.0
CSH3_k127_5095811_2 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 354.0
CSH3_k127_5095811_3 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000003424 103.0
CSH3_k127_5143006_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 531.0
CSH3_k127_5143006_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 297.0
CSH3_k127_5143006_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000001036 51.0
CSH3_k127_5240271_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1229.0
CSH3_k127_5240271_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
CSH3_k127_5240271_2 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000005978 182.0
CSH3_k127_5246808_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 389.0
CSH3_k127_5246808_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000007536 140.0
CSH3_k127_5271773_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 521.0
CSH3_k127_5271773_1 PFAM ApbE family K09740 - - 0.00008226 45.0
CSH3_k127_5294964_0 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 473.0
CSH3_k127_5294964_1 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000003613 185.0
CSH3_k127_530228_0 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 403.0
CSH3_k127_530228_1 - K07275 - - 0.00000000000000000000000000000000000000000000000000002994 195.0
CSH3_k127_530228_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000002197 103.0
CSH3_k127_5307467_0 PFAM elongation factor Tu domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 360.0
CSH3_k127_5307467_1 plastoquinone (Complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007501 256.0
CSH3_k127_5307467_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000007661 55.0
CSH3_k127_5322360_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 348.0
CSH3_k127_5322360_1 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.0000000000000000000000000000000000000000000002407 170.0
CSH3_k127_5322360_2 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000141 110.0
CSH3_k127_5322360_3 B-block binding subunit of TFIIIC - - - 0.000000000000000000000001728 106.0
CSH3_k127_5345991_0 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 549.0
CSH3_k127_5345991_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 492.0
CSH3_k127_5345991_10 Transposase and inactivated derivatives - - - 0.0000000000000002521 80.0
CSH3_k127_5345991_2 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 484.0
CSH3_k127_5345991_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 452.0
CSH3_k127_5345991_4 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 452.0
CSH3_k127_5345991_5 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02588,K21610 - 1.18.6.1,6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 387.0
CSH3_k127_5345991_6 PFAM Glycosyl transferase family 2 K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 323.0
CSH3_k127_5345991_7 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002108 269.0
CSH3_k127_5345991_8 KH domain protein K06961 - - 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
CSH3_k127_5345991_9 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000003164 151.0
CSH3_k127_5350985_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 522.0
CSH3_k127_5350985_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000009118 193.0
CSH3_k127_5350985_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000003156 120.0
CSH3_k127_5350985_3 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000004218 91.0
CSH3_k127_5364715_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 4.783e-271 850.0
CSH3_k127_5364715_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 358.0
CSH3_k127_5364715_2 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000000000000000000000000000000005432 207.0
CSH3_k127_5364715_3 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000006649 193.0
CSH3_k127_5364715_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162 - 1.2.4.1 0.00000000000000000000000000000000000118 151.0
CSH3_k127_5364715_5 nucleotidyltransferase activity - - - 0.00000000000002216 81.0
CSH3_k127_5382455_0 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 488.0
CSH3_k127_5382455_1 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.0000000000005005 71.0
CSH3_k127_5416807_0 RNA ligase K07468 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 333.0
CSH3_k127_5416807_1 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 319.0
CSH3_k127_5416807_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 301.0
CSH3_k127_5416807_3 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003301 246.0
CSH3_k127_5416807_4 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000009118 216.0
CSH3_k127_5416807_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000001197 143.0
CSH3_k127_5416807_6 Helix-turn-helix XRE-family like proteins K03627 - - 0.00000000000000002687 83.0
CSH3_k127_5416807_7 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000002114 51.0
CSH3_k127_5419818_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 501.0
CSH3_k127_5419818_1 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000002784 255.0
CSH3_k127_5419818_2 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000008689 164.0
CSH3_k127_5419818_3 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000000000001374 132.0
CSH3_k127_5419818_4 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000001554 83.0
CSH3_k127_5421139_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 554.0
CSH3_k127_5421139_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003977 241.0
CSH3_k127_5421139_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000001528 236.0
CSH3_k127_5421139_3 plastoquinone (Complex I) K12141 - - 0.00000000000000000000000000000000000000000000000000000000000002205 219.0
CSH3_k127_5421139_4 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K12143 - - 0.000000000000000000000000292 109.0
CSH3_k127_5421139_5 universal stress protein - - - 0.000002665 55.0
CSH3_k127_5438735_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1579.0
CSH3_k127_5438735_1 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000003354 131.0
CSH3_k127_5438735_2 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000004457 93.0
CSH3_k127_5452232_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 394.0
CSH3_k127_5452232_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 301.0
CSH3_k127_5452232_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002638 217.0
CSH3_k127_5452232_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000002165 137.0
CSH3_k127_5452232_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K22166 - 1.5.98.3 0.000000000000000000000000000000003708 131.0
CSH3_k127_5452232_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000006366 108.0
CSH3_k127_5452232_6 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K22167 - 1.5.98.3 0.0000000000000000000000019 105.0
CSH3_k127_5452232_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.0000000000001942 72.0
CSH3_k127_5452232_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000001286 50.0
CSH3_k127_5458425_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.368e-216 677.0
CSH3_k127_5458425_1 PFAM GTP-binding protein HSR1-related K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 339.0
CSH3_k127_5458425_10 - - - - 0.000000000000000000002885 100.0
CSH3_k127_5458425_11 Belongs to the sulfur carrier protein TusA family - - - 0.000000000003663 67.0
CSH3_k127_5458425_12 - - - - 0.0000000006695 65.0
CSH3_k127_5458425_2 ZPR1-related zinc finger protein K06874 - - 0.00000000000000000000000000000000000000000000000000000000000002957 220.0
CSH3_k127_5458425_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000152 183.0
CSH3_k127_5458425_4 PFAM PUA domain containing protein K07575 - - 0.000000000000000000000000000000000000000000000001339 178.0
CSH3_k127_5458425_5 Zn-ribbon containing protein K07163 - - 0.0000000000000000000000000000000000000001653 153.0
CSH3_k127_5458425_6 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.00000000000000000000000000000000000001509 147.0
CSH3_k127_5458425_7 Pfam:DUF552 K09152 - - 0.0000000000000000000000000000000005805 134.0
CSH3_k127_5458425_8 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.00000000000000000000000000001298 119.0
CSH3_k127_5458425_9 binds to the 23S rRNA K02922 - - 0.0000000000000000000001471 97.0
CSH3_k127_546727_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000001395 185.0
CSH3_k127_546727_1 Necessary for normal cell division and for the maintenance of normal septation - - - 0.000000000000000000000000000000000004864 140.0
CSH3_k127_546727_2 Protein of unknown function (DUF356) K09727 - - 0.0000000000000000000000000000003611 126.0
CSH3_k127_5481332_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.018e-299 929.0
CSH3_k127_5481332_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 585.0
CSH3_k127_5481332_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 542.0
CSH3_k127_5481332_3 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 493.0
CSH3_k127_5481332_4 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 303.0
CSH3_k127_5481332_5 Protein of unknown function (DUF1699) - - - 0.0000000000000000000000000000000000000000000000000001294 188.0
CSH3_k127_5481332_6 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000006268 62.0
CSH3_k127_5481332_7 Transposase IS116/IS110/IS902 family - - - 0.000007298 50.0
CSH3_k127_5505990_0 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 521.0
CSH3_k127_5505990_1 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 315.0
CSH3_k127_5510251_0 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 400.0
CSH3_k127_5510251_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 340.0
CSH3_k127_5510251_2 Segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000000000000000000000000000000000001447 214.0
CSH3_k127_5510251_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000508 104.0
CSH3_k127_5523949_0 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
CSH3_k127_5523949_1 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000004067 136.0
CSH3_k127_5523949_2 cheY-homologous receiver domain - - - 0.000000000000009766 79.0
CSH3_k127_5523949_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000002807 51.0
CSH3_k127_5533116_0 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 465.0
CSH3_k127_5533116_1 COGs COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000001191 98.0
CSH3_k127_5571938_0 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 302.0
CSH3_k127_5571938_1 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 288.0
CSH3_k127_5571938_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000034 281.0
CSH3_k127_5571938_3 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000007974 222.0
CSH3_k127_5571938_4 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000000004875 145.0
CSH3_k127_5571938_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000005582 63.0
CSH3_k127_5641245_0 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
CSH3_k127_5641245_1 Clp protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007401 246.0
CSH3_k127_5748458_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 464.0
CSH3_k127_5748458_1 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 388.0
CSH3_k127_5748458_2 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 384.0
CSH3_k127_5748458_3 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000009719 258.0
CSH3_k127_5748458_4 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000001925 143.0
CSH3_k127_5748458_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000004595 139.0
CSH3_k127_5748458_6 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000000002129 125.0
CSH3_k127_5755834_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000009263 108.0
CSH3_k127_5755834_1 ABC-2 family transporter protein K01992 - - 0.0000000000000002842 92.0
CSH3_k127_5761723_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
CSH3_k127_5761723_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000001075 74.0
CSH3_k127_5761723_2 MjaI restriction endonuclease - - - 0.00001098 48.0
CSH3_k127_5777_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.196e-308 961.0
CSH3_k127_5781970_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 528.0
CSH3_k127_5781970_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000002203 177.0
CSH3_k127_5790789_0 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 342.0
CSH3_k127_5790789_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 302.0
CSH3_k127_5800974_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 417.0
CSH3_k127_5800974_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000006226 120.0
CSH3_k127_5800974_2 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000000000000000000000000007894 114.0
CSH3_k127_5800974_3 - - - - 0.0000000000000000001223 90.0
CSH3_k127_5811626_0 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001637 267.0
CSH3_k127_5811626_1 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000001857 218.0
CSH3_k127_5811626_2 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000002309 120.0
CSH3_k127_5853121_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 489.0
CSH3_k127_5853121_1 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000001681 186.0
CSH3_k127_5855553_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 6.322e-204 640.0
CSH3_k127_5855553_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 502.0
CSH3_k127_5855553_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000001285 126.0
CSH3_k127_5861908_0 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 406.0
CSH3_k127_5861908_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 342.0
CSH3_k127_5861908_2 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000302 177.0
CSH3_k127_5861908_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000005533 69.0
CSH3_k127_5861908_4 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.00000004816 58.0
CSH3_k127_5890379_0 CcmB protein K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007586 266.0
CSH3_k127_5890379_1 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000001979 248.0
CSH3_k127_5890379_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000016 86.0
CSH3_k127_5968189_0 urocanate hydratase activity K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.834e-224 708.0
CSH3_k127_5968189_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 450.0
CSH3_k127_5968189_2 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000001799 224.0
CSH3_k127_5968189_3 Belongs to the arginase family K01479 - 3.5.3.8 0.000000000000000000000000000000000000000000000000000001659 203.0
CSH3_k127_5968189_4 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000003298 100.0
CSH3_k127_6076149_0 PFAM PilT protein domain protein K06865 - - 1.117e-221 703.0
CSH3_k127_6076149_1 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 431.0
CSH3_k127_6076149_2 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001686 212.0
CSH3_k127_6076149_3 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000001735 156.0
CSH3_k127_6083815_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 515.0
CSH3_k127_6083815_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000004443 240.0
CSH3_k127_6083815_2 AAA-like domain K06915 - - 0.000002515 53.0
CSH3_k127_6090844_0 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 411.0
CSH3_k127_6090844_1 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 410.0
CSH3_k127_6090844_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000005197 82.0
CSH3_k127_6123691_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 467.0
CSH3_k127_6144615_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 524.0
CSH3_k127_6144615_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 300.0
CSH3_k127_6144615_2 RNA methylase K07446 - 2.1.1.213 0.000000000000000000005283 98.0
CSH3_k127_6148202_0 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 384.0
CSH3_k127_6148202_1 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002276 271.0
CSH3_k127_6148202_2 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000001189 212.0
CSH3_k127_6148202_3 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.000000000000000000000000002506 112.0
CSH3_k127_6148202_4 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000008977 111.0
CSH3_k127_6148202_5 4Fe-4S binding domain K00171 - 1.2.7.1 0.00000000000000000002492 102.0
CSH3_k127_6148202_6 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.00000000000000000005114 91.0
CSH3_k127_6148202_7 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.0000000000000000005972 88.0
CSH3_k127_6159300_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 513.0
CSH3_k127_6159300_1 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 367.0
CSH3_k127_6159300_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000879 212.0
CSH3_k127_6159300_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000195 185.0
CSH3_k127_6159300_4 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000000000000000000001844 133.0
CSH3_k127_6159300_5 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000002 102.0
CSH3_k127_6159300_6 Transposase IS66 family - - - 0.00000000116 61.0
CSH3_k127_6159300_7 PFAM Methyltransferase type 11 - - - 0.000004995 55.0
CSH3_k127_6159300_8 Transcriptional regulators - - - 0.00001681 50.0
CSH3_k127_6159300_9 Protein of unknown function DUF45 K07043 - - 0.0008326 44.0
CSH3_k127_618681_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 2.897e-240 758.0
CSH3_k127_618681_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 9.415e-195 617.0
CSH3_k127_618681_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 295.0
CSH3_k127_618681_3 MULE transposase domain - - - 0.0008862 50.0
CSH3_k127_6199572_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 497.0
CSH3_k127_6199572_1 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.000000000000000000000000000000000000000000000000000000000414 207.0
CSH3_k127_6199572_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000002654 145.0
CSH3_k127_6199572_3 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000000105 108.0
CSH3_k127_6199572_4 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000004005 86.0
CSH3_k127_6199572_5 nuclease activity K18828 - - 0.00001893 50.0
CSH3_k127_6207919_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006971 233.0
CSH3_k127_6207919_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000001068 222.0
CSH3_k127_6207919_2 Prokaryotic N-terminal methylation motif - - - 0.0000000000001108 72.0
CSH3_k127_6207919_3 PFAM Lytic transglycosylase catalytic - - - 0.00000000003209 68.0
CSH3_k127_6221302_0 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000473 270.0
CSH3_k127_6221302_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000001877 149.0
CSH3_k127_6221302_2 AAA ATPase domain - - - 0.000000000000000000000000000003537 122.0
CSH3_k127_6221302_3 PFAM RNA-binding protein K06964 - - 0.000001204 51.0
CSH3_k127_6251527_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000001722 237.0
CSH3_k127_6251527_1 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000002198 171.0
CSH3_k127_6251527_2 UbiD family K03182 - 4.1.1.98 0.00000000000000000000000153 104.0
CSH3_k127_6251527_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000002753 52.0
CSH3_k127_6251527_4 Ribonuclease III family - - - 0.0004734 47.0
CSH3_k127_6257275_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 1.106e-287 893.0
CSH3_k127_6257275_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003201 272.0
CSH3_k127_6265990_0 Clp protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000001089 240.0
CSH3_k127_6265990_1 PFAM regulatory protein, ArsR K07721 - - 0.000000000000000000000000000000000000000003177 162.0
CSH3_k127_6265990_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000001973 53.0
CSH3_k127_6281456_0 radical SAM domain protein K09711 - - 0.000000000000000000000000000000000000000000000000000007097 201.0
CSH3_k127_6281456_1 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000002947 137.0
CSH3_k127_6281456_2 - - - - 0.00000000000001883 80.0
CSH3_k127_6310875_0 Cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 432.0
CSH3_k127_6310875_1 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 364.0
CSH3_k127_6310875_2 Fe-S cluster K04488 - - 0.00000000000000000000000000000000000000000000000000000001216 210.0
CSH3_k127_6310875_3 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000000608 162.0
CSH3_k127_6310875_4 Non-histone chromosomal protein MC1 - - - 0.00000000000000000000000000000000000000003507 154.0
CSH3_k127_6310875_5 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000122 148.0
CSH3_k127_6310875_6 Rubrerythrin K19824 - - 0.00000000000007507 72.0
CSH3_k127_6329751_0 PFAM ferredoxin-dependent glutamate synthase - - - 9.876e-289 892.0
CSH3_k127_6329751_1 - - - - 0.0000000001505 65.0
CSH3_k127_6345676_0 Translation initiation factor 2 alpha subunit K03237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 332.0
CSH3_k127_6345676_1 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 306.0
CSH3_k127_6345676_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000001585 190.0
CSH3_k127_6345676_3 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000001093 151.0
CSH3_k127_6345676_4 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000002677 138.0
CSH3_k127_6345676_5 protein conserved in archaea K09723 - - 0.00000000000000000000001452 109.0
CSH3_k127_6345676_6 PFAM Ribosomal protein S27E K02978 - - 0.000000000000000000000077 98.0
CSH3_k127_6345676_7 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000328 64.0
CSH3_k127_6372930_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 421.0
CSH3_k127_6372930_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000001202 161.0
CSH3_k127_6372930_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000003738 132.0
CSH3_k127_6372930_3 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000002505 92.0
CSH3_k127_6411524_0 Arsenical pump membrane protein K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 425.0
CSH3_k127_6411524_1 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 356.0
CSH3_k127_6411524_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000000001353 91.0
CSH3_k127_6424774_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 7.093e-197 618.0
CSH3_k127_6424774_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000003253 196.0
CSH3_k127_6424774_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000004698 65.0
CSH3_k127_6448159_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 535.0
CSH3_k127_6448159_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 487.0
CSH3_k127_6448159_2 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 371.0
CSH3_k127_6448159_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000000000000000000000001214 233.0
CSH3_k127_6448159_4 methyltransferase small K07579 - - 0.00000000000000000000000000000000000000005089 154.0
CSH3_k127_6448159_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000001889 149.0
CSH3_k127_6448159_6 - - - - 0.0000000000000000000000000000000009349 136.0
CSH3_k127_6448159_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000000000000249 108.0
CSH3_k127_6448159_8 protein conserved in archaea - - - 0.0000000000000000000000004738 110.0
CSH3_k127_6491879_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 411.0
CSH3_k127_6491879_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000406 124.0
CSH3_k127_6491879_2 - - - - 0.00000000000000001948 85.0
CSH3_k127_6491879_3 Probable zinc-ribbon domain - - - 0.0000000000002344 70.0
CSH3_k127_6491879_4 - - - - 0.000000000001341 68.0
CSH3_k127_6491879_5 - - - - 0.00000000002257 68.0
CSH3_k127_6491879_6 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00002252 55.0
CSH3_k127_6493627_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 583.0
CSH3_k127_6493627_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 293.0
CSH3_k127_6493627_2 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000001591 235.0
CSH3_k127_6493627_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
CSH3_k127_6493627_4 BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000000006676 196.0
CSH3_k127_6493627_5 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000000000000001429 166.0
CSH3_k127_6493627_6 - K00960 - 2.7.7.6 0.0000000000000000000004083 96.0
CSH3_k127_6493627_7 - - - - 0.000000000000000002544 92.0
CSH3_k127_6494550_0 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 397.0
CSH3_k127_6494550_1 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000001235 190.0
CSH3_k127_6494550_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000001392 146.0
CSH3_k127_6494550_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000001365 70.0
CSH3_k127_6514347_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1176.0
CSH3_k127_6514347_1 TIGRFAM small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 495.0
CSH3_k127_6514347_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 488.0
CSH3_k127_6514347_3 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000001642 225.0
CSH3_k127_6514347_4 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000001215 204.0
CSH3_k127_6514347_5 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000001926 207.0
CSH3_k127_6514347_6 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000009304 100.0
CSH3_k127_6514347_7 - - - - 0.000000000000003315 88.0
CSH3_k127_6514347_8 - - - - 0.00000001895 63.0
CSH3_k127_6514347_9 N-4 methylation of cytosine - - - 0.0002061 44.0
CSH3_k127_6526326_0 FAD binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 520.0
CSH3_k127_6526326_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000002083 267.0
CSH3_k127_6526326_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000007169 252.0
CSH3_k127_6526326_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000001027 143.0
CSH3_k127_6526326_4 SigmaK-factor processing regulatory protein BofA - - - 0.000000007223 59.0
CSH3_k127_6530652_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1129.0
CSH3_k127_6530652_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 398.0
CSH3_k127_6530652_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 351.0
CSH3_k127_6538123_0 Metallo-beta-lactamase superfamily K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 340.0
CSH3_k127_6538123_1 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 301.0
CSH3_k127_6538123_2 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000001505 109.0
CSH3_k127_6538123_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000001212 104.0
CSH3_k127_6605358_0 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 531.0
CSH3_k127_6605358_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000002044 195.0
CSH3_k127_6605358_2 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000013 186.0
CSH3_k127_6605358_3 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000005626 167.0
CSH3_k127_6605358_4 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.00000000000000009077 83.0
CSH3_k127_6605358_5 RNA cap guanine-N2 methyltransferase - - - 0.000000008282 57.0
CSH3_k127_6605358_6 Protein of unknown function DUF72 - - - 0.0001591 47.0
CSH3_k127_6605528_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1170.0
CSH3_k127_6605528_1 protein containing a TIR (Toll-Interleukin 1-resistance) domain - - - 0.00000000000000000000000000000000000000001581 162.0
CSH3_k127_6605528_2 Nucleotidyltransferase domain - - - 0.0000000000000000000006033 101.0
CSH3_k127_6630621_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 507.0
CSH3_k127_6630621_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 477.0
CSH3_k127_6630621_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 354.0
CSH3_k127_6630621_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001191 256.0
CSH3_k127_6658430_0 Domain of unknown function (DUF1743) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 386.0
CSH3_k127_6658430_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000002158 138.0
CSH3_k127_6724843_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 551.0
CSH3_k127_6724843_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001724 275.0
CSH3_k127_6729408_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000001516 231.0
CSH3_k127_6729408_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000003454 188.0
CSH3_k127_6729408_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000003458 141.0
CSH3_k127_673005_0 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 501.0
CSH3_k127_673005_1 Family of unknown function (DUF5328) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 310.0
CSH3_k127_673005_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000009757 190.0
CSH3_k127_673005_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.0000000000000000000000000000000000000000000001058 169.0
CSH3_k127_673005_4 Protein of unknown function DUF86 - - - 0.00000000001187 66.0
CSH3_k127_6803909_0 Belongs to the MCM family K10726 - - 6.922e-269 843.0
CSH3_k127_6803909_1 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000000299 96.0
CSH3_k127_6803909_2 archaeal coiled-coil protein - - - 0.0000000000000000001053 93.0
CSH3_k127_6803909_3 - - - - 0.000000000001272 76.0
CSH3_k127_6862214_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 483.0
CSH3_k127_6862214_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 297.0
CSH3_k127_6862214_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000249 280.0
CSH3_k127_6862214_3 - - - - 0.00000001257 60.0
CSH3_k127_6862214_4 Zinc-finger associated domain (zf-AD) - - - 0.00001163 54.0
CSH3_k127_6871912_0 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 536.0
CSH3_k127_6871912_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 342.0
CSH3_k127_6871912_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 332.0
CSH3_k127_6871912_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000002396 109.0
CSH3_k127_696762_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 533.0
CSH3_k127_696762_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.000000000000000000000001973 104.0
CSH3_k127_696762_2 Pfam:DUF2276 - - - 0.0000002247 53.0
CSH3_k127_705487_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 486.0
CSH3_k127_705487_1 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000005879 157.0
CSH3_k127_717479_0 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 357.0
CSH3_k127_717479_1 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K08321,K11645 - 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003253 281.0
CSH3_k127_717479_2 LVIVD repeat K03929,K07017,K12287 - - 0.0000000411 63.0
CSH3_k127_73608_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 351.0
CSH3_k127_73608_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 323.0
CSH3_k127_73608_2 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 300.0
CSH3_k127_73608_3 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000009464 220.0
CSH3_k127_73608_4 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000011 199.0
CSH3_k127_73608_5 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000001162 173.0
CSH3_k127_741803_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 419.0
CSH3_k127_741803_1 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.000000000000000000000000000000000000000000000000000000000000000000000003517 247.0
CSH3_k127_741803_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K00657,K03825 - 2.3.1.57 0.0000000000000003219 81.0
CSH3_k127_7428_0 - - - - 4.737e-228 723.0
CSH3_k127_7428_1 - - - - 0.00000000000000000000004255 105.0
CSH3_k127_7428_2 - - - - 0.00005243 51.0
CSH3_k127_747002_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 321.0
CSH3_k127_747002_1 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008934 271.0
CSH3_k127_747002_2 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000003074 182.0
CSH3_k127_747002_3 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 - - 0.00000000000000000000008499 100.0
CSH3_k127_747002_4 - - - - 0.000000000000000000005169 93.0
CSH3_k127_763979_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 445.0
CSH3_k127_763979_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 295.0
CSH3_k127_763979_2 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000009066 144.0
CSH3_k127_76803_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 4.57e-218 681.0
CSH3_k127_76803_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000001075 177.0
CSH3_k127_768558_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.39e-306 955.0
CSH3_k127_768558_1 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 292.0
CSH3_k127_768558_2 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000238 274.0
CSH3_k127_77347_0 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001219 257.0
CSH3_k127_77347_1 PAC2 family K07159 - - 0.0000000000000000000000005393 115.0
CSH3_k127_77347_2 conserved protein involved in oxidation of intracellular sulfur K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.00025 45.0
CSH3_k127_791339_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.196e-265 826.0
CSH3_k127_791339_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 474.0
CSH3_k127_791339_2 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000159 181.0
CSH3_k127_84545_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 360.0
CSH3_k127_84545_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001503 279.0
CSH3_k127_84545_2 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000000003111 200.0
CSH3_k127_84545_3 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000366 184.0
CSH3_k127_84545_4 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000001009 141.0
CSH3_k127_84545_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000002063 117.0
CSH3_k127_865170_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 2.826e-216 683.0
CSH3_k127_865170_1 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 575.0
CSH3_k127_865170_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 355.0
CSH3_k127_865170_3 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 298.0
CSH3_k127_865170_4 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 296.0
CSH3_k127_865170_5 PFAM glycosyl transferase group 1 K13677 - 2.4.1.208 0.000000000000000000000000000000000000001934 159.0
CSH3_k127_86891_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 608.0
CSH3_k127_86891_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 588.0
CSH3_k127_86891_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 512.0
CSH3_k127_86891_3 SNARE associated Golgi protein K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.000000000000000000000000000000000000000000002251 169.0
CSH3_k127_880638_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 1.039e-197 627.0
CSH3_k127_89433_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1289.0
CSH3_k127_89433_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 7.929e-234 728.0
CSH3_k127_89433_10 toxin-antitoxin pair type II binding - - - 0.000000000000000000000002838 104.0
CSH3_k127_89433_11 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000000008191 94.0
CSH3_k127_89433_12 PFAM Methyltransferase type 11 - - - 0.0000001886 55.0
CSH3_k127_89433_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 2.687e-209 662.0
CSH3_k127_89433_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 479.0
CSH3_k127_89433_4 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 342.0
CSH3_k127_89433_5 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009368 278.0
CSH3_k127_89433_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 240.0
CSH3_k127_89433_7 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000005989 216.0
CSH3_k127_89433_8 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000157 202.0
CSH3_k127_89433_9 transcription termination protein NusA K02600 - - 0.00000000000000000000000000000000000000000000000000001302 191.0
CSH3_k127_896499_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 478.0
CSH3_k127_896499_1 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 326.0
CSH3_k127_896499_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000001186 121.0
CSH3_k127_90435_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 593.0
CSH3_k127_90435_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 366.0
CSH3_k127_90435_2 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000107 254.0
CSH3_k127_90435_3 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000000000002412 151.0
CSH3_k127_90435_4 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000022 96.0
CSH3_k127_90435_5 Domain of unknown function (DUF1858) - - - 0.00000000000000000004142 93.0
CSH3_k127_90435_6 - - - - 0.00000002369 57.0
CSH3_k127_908176_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 423.0
CSH3_k127_908176_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000005119 263.0
CSH3_k127_908176_2 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000000000000000004313 166.0
CSH3_k127_908176_3 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.00000000000000000000000000000199 126.0
CSH3_k127_912115_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 448.0
CSH3_k127_912115_1 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 425.0
CSH3_k127_912115_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
CSH3_k127_912115_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002316 250.0
CSH3_k127_912634_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 587.0
CSH3_k127_912634_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 361.0
CSH3_k127_912634_2 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000926 262.0
CSH3_k127_912634_3 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000001857 136.0
CSH3_k127_912634_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000009296 123.0
CSH3_k127_931467_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 339.0
CSH3_k127_931467_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000004776 245.0
CSH3_k127_945005_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1159.0
CSH3_k127_945005_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 370.0
CSH3_k127_945005_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 324.0
CSH3_k127_945005_3 extracellular solute-binding protein, family 1 K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006246 270.0
CSH3_k127_945005_4 Family of unknown function (DUF5371) - - - 0.000006353 50.0
CSH3_k127_953621_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 452.0
CSH3_k127_953621_1 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 417.0
CSH3_k127_953621_2 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000001646 195.0
CSH3_k127_962221_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 608.0
CSH3_k127_962221_1 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000001003 121.0
CSH3_k127_962221_2 Homeodomain-like domain - - - 0.000002321 50.0
CSH3_k127_969660_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 580.0
CSH3_k127_969660_1 - - - - 0.0000000000000000000000000000000000005001 148.0
CSH3_k127_969660_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000001643 81.0
CSH3_k127_97298_0 - - - - 0.0000000000000000000000000000000000000000000000003592 192.0
CSH3_k127_97298_1 - - - - 0.0000000000000000000000000001612 130.0
CSH3_k127_97298_2 - - - - 0.0001465 48.0
CSH3_k127_979463_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 2.406e-222 697.0
CSH3_k127_979463_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 2.525e-207 651.0
CSH3_k127_979463_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001316 288.0
CSH3_k127_979463_3 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003156 269.0