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Overview

ID MAG00679
Name DPH1_bin.26
Sample SMP0019
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species
Assembly information
Completeness (%) 64.69
Contamination (%) 0.99
GC content (%) 45.0
N50 (bp) 33,877
Genome size (bp) 1,204,771

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes995

Gene name Description KEGG GOs EC E-value Score Sequence
DPH1_k127_10163292_0 Peptidase family M28 K05994 - 3.4.11.10 0.0000000000000000000000000000006985 139.0
DPH1_k127_10163292_1 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.000000000000000000000000000001932 138.0
DPH1_k127_10163292_2 Transcriptional regulator K07729 - - 0.00000000000000000000001518 102.0
DPH1_k127_10163292_3 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.0000000000006334 76.0
DPH1_k127_10163292_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000007002 78.0
DPH1_k127_1034041_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 396.0
DPH1_k127_1034041_1 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000005629 232.0
DPH1_k127_1034041_2 Peptidase family C25 - - - 0.00000001754 68.0
DPH1_k127_1034041_3 cell redox homeostasis K17264 GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0005793,GO:0006457,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006986,GO:0008150,GO:0008152,GO:0009100,GO:0009986,GO:0009987,GO:0010033,GO:0012505,GO:0015036,GO:0015037,GO:0016020,GO:0016192,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0019725,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0031984,GO:0032940,GO:0033554,GO:0034774,GO:0034976,GO:0035580,GO:0035966,GO:0036230,GO:0042119,GO:0042175,GO:0042221,GO:0042581,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045454,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055114,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0097708,GO:0098827,GO:0099503,GO:0140096,GO:1901135,GO:1901564 - 0.00000002506 61.0
DPH1_k127_1034041_4 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000007539 64.0
DPH1_k127_1034041_5 Domain of unknown function (DUF2341) - - - 0.0001828 56.0
DPH1_k127_10395854_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 3.402e-271 863.0
DPH1_k127_10395854_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 484.0
DPH1_k127_10395854_2 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 320.0
DPH1_k127_10395854_3 COG1520 FOG WD40-like repeat - - - 0.00000000000000000001673 109.0
DPH1_k127_10602393_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 528.0
DPH1_k127_10602393_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
DPH1_k127_10602393_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001705 245.0
DPH1_k127_10602393_3 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001078 255.0
DPH1_k127_10602393_4 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000002817 248.0
DPH1_k127_10602393_5 Protein of unknown function (DUF996) - - - 0.000000000000000000000000000000000004226 148.0
DPH1_k127_10602393_6 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.000000000000000000000001077 116.0
DPH1_k127_10602393_7 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000009917 90.0
DPH1_k127_10602393_8 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000000000000000001182 100.0
DPH1_k127_10602393_9 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000003504 85.0
DPH1_k127_11248702_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1459.0
DPH1_k127_11248702_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.528e-298 926.0
DPH1_k127_11248702_10 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 328.0
DPH1_k127_11248702_11 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 327.0
DPH1_k127_11248702_12 transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 311.0
DPH1_k127_11248702_13 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 300.0
DPH1_k127_11248702_14 calcium proton exchanger K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 293.0
DPH1_k127_11248702_15 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 292.0
DPH1_k127_11248702_16 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 303.0
DPH1_k127_11248702_17 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 278.0
DPH1_k127_11248702_18 ATPases associated with a variety of cellular activities K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007812 270.0
DPH1_k127_11248702_19 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005433 242.0
DPH1_k127_11248702_2 helicase activity - - - 1.547e-241 763.0
DPH1_k127_11248702_20 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000006071 237.0
DPH1_k127_11248702_21 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003684 235.0
DPH1_k127_11248702_22 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000429 230.0
DPH1_k127_11248702_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000001534 226.0
DPH1_k127_11248702_24 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000004438 222.0
DPH1_k127_11248702_25 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.000000000000000000000000000000000000000000000000000000000001848 216.0
DPH1_k127_11248702_26 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000004528 224.0
DPH1_k127_11248702_27 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000001499 213.0
DPH1_k127_11248702_28 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.000000000000000000000000000000000000000000000000000000002705 213.0
DPH1_k127_11248702_29 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000001954 211.0
DPH1_k127_11248702_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 606.0
DPH1_k127_11248702_30 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000006974 206.0
DPH1_k127_11248702_31 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000009439 203.0
DPH1_k127_11248702_32 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.000000000000000000000000000000000000000000000000000002459 204.0
DPH1_k127_11248702_33 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000003291 209.0
DPH1_k127_11248702_34 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000002985 186.0
DPH1_k127_11248702_35 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000007192 171.0
DPH1_k127_11248702_36 - - - - 0.0000000000000000000000000000000000000000001372 167.0
DPH1_k127_11248702_37 PFAM helix-turn-helix HxlR type - - - 0.00000000000000000000000000000000000000009575 153.0
DPH1_k127_11248702_38 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000008143 143.0
DPH1_k127_11248702_39 Predicted SAM-dependent RNA methyltransferase - - - 0.00000000000000000000000000000004204 134.0
DPH1_k127_11248702_4 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 595.0
DPH1_k127_11248702_40 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000003161 134.0
DPH1_k127_11248702_41 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000000002609 124.0
DPH1_k127_11248702_42 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000008058 106.0
DPH1_k127_11248702_43 Papain family cysteine protease - - - 0.00000000000000000000000635 117.0
DPH1_k127_11248702_44 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000004006 91.0
DPH1_k127_11248702_45 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000001075 87.0
DPH1_k127_11248702_46 - - - - 0.00000000000000003522 83.0
DPH1_k127_11248702_47 PFAM conserved K07027 - - 0.000000000003977 77.0
DPH1_k127_11248702_48 Circadian clock protein KaiC - - - 0.00000001131 65.0
DPH1_k127_11248702_49 Peptidase family C25 - - - 0.00000003708 66.0
DPH1_k127_11248702_5 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 574.0
DPH1_k127_11248702_50 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000001297 57.0
DPH1_k127_11248702_52 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0008211 52.0
DPH1_k127_11248702_6 UPF0313 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 422.0
DPH1_k127_11248702_7 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 391.0
DPH1_k127_11248702_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 338.0
DPH1_k127_11248702_9 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 357.0
DPH1_k127_11325891_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.32e-277 872.0
DPH1_k127_11325891_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000003075 193.0
DPH1_k127_11325891_10 Periplasmic binding protein K02016 - - 0.0000000000003973 77.0
DPH1_k127_11325891_12 PFAM major facilitator superfamily MFS_1 - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000002744 66.0
DPH1_k127_11325891_13 AsnC-type helix-turn-helix domain - - - 0.0000958 51.0
DPH1_k127_11325891_2 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000006164 167.0
DPH1_k127_11325891_3 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000001305 142.0
DPH1_k127_11325891_4 4 iron, 4 sulfur cluster binding K00196 - - 0.000000000000000000000000000001192 127.0
DPH1_k127_11325891_5 GPR1 FUN34 yaaH family protein K07034 - - 0.00000000000000000000000001375 117.0
DPH1_k127_11325891_6 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000002487 111.0
DPH1_k127_11325891_7 serine threonine protein kinase - - - 0.000000000000000000008467 102.0
DPH1_k127_11325891_8 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.000000000000002003 84.0
DPH1_k127_11325891_9 - - - - 0.000000000000009449 80.0
DPH1_k127_11573296_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 338.0
DPH1_k127_11573296_1 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000004889 195.0
DPH1_k127_11573296_2 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000005636 155.0
DPH1_k127_11573296_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001825 102.0
DPH1_k127_11573296_4 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000007715 75.0
DPH1_k127_11573296_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000001429 64.0
DPH1_k127_1162821_0 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 517.0
DPH1_k127_1162821_1 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 488.0
DPH1_k127_1162821_10 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000005597 218.0
DPH1_k127_1162821_11 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000005117 192.0
DPH1_k127_1162821_12 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000001313 196.0
DPH1_k127_1162821_13 Papain family cysteine protease K14647 - - 0.00000000000000000000000000000000000000000000000002971 196.0
DPH1_k127_1162821_14 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000001991 171.0
DPH1_k127_1162821_15 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000003255 156.0
DPH1_k127_1162821_16 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000005102 148.0
DPH1_k127_1162821_17 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000004672 143.0
DPH1_k127_1162821_18 Family of unknown function (DUF438) K09155 - - 0.00000000000000000000000000001861 123.0
DPH1_k127_1162821_19 archaeal coiled-coil protein - - - 0.00000000000000000000000001873 120.0
DPH1_k127_1162821_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 479.0
DPH1_k127_1162821_20 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000004102 106.0
DPH1_k127_1162821_21 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000004606 97.0
DPH1_k127_1162821_22 Protein of unknown function (DUF3795) - - - 0.0000000000000000004187 88.0
DPH1_k127_1162821_23 Protein of unknown function (DUF1614) - - - 0.000000000000000002998 94.0
DPH1_k127_1162821_24 PFAM helix-turn-helix domain protein K03627 - - 0.0000000000002421 76.0
DPH1_k127_1162821_25 ABC-type uncharacterized transport system - - - 0.000000000499 73.0
DPH1_k127_1162821_26 amine dehydrogenase activity - - - 0.000000001087 73.0
DPH1_k127_1162821_27 COG1522 Transcriptional regulators - - - 0.0000001167 60.0
DPH1_k127_1162821_28 Protein of unknown function (DUF3795) - - - 0.000002599 50.0
DPH1_k127_1162821_29 - - - - 0.000006353 50.0
DPH1_k127_1162821_3 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 439.0
DPH1_k127_1162821_31 oxidoreductase activity K02396 - - 0.00009573 49.0
DPH1_k127_1162821_33 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0004156 47.0
DPH1_k127_1162821_4 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 371.0
DPH1_k127_1162821_5 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 336.0
DPH1_k127_1162821_6 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 332.0
DPH1_k127_1162821_7 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002184 289.0
DPH1_k127_1162821_8 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
DPH1_k127_1162821_9 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003765 248.0
DPH1_k127_11634594_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1138.0
DPH1_k127_11634594_1 Cell division protein 48 (CDC48) N-terminal domain K13525 - - 1.702e-276 874.0
DPH1_k127_11634594_10 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006108 271.0
DPH1_k127_11634594_11 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005123 261.0
DPH1_k127_11634594_12 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000236 251.0
DPH1_k127_11634594_13 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000332 258.0
DPH1_k127_11634594_14 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000111 236.0
DPH1_k127_11634594_15 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000001241 214.0
DPH1_k127_11634594_16 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000002849 222.0
DPH1_k127_11634594_17 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000006356 204.0
DPH1_k127_11634594_18 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000638 206.0
DPH1_k127_11634594_19 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000002528 196.0
DPH1_k127_11634594_2 DNA gyrase topoisomerase IV, subunit A K02469 GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 1.252e-268 876.0
DPH1_k127_11634594_20 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000002927 185.0
DPH1_k127_11634594_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000001472 183.0
DPH1_k127_11634594_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000005097 143.0
DPH1_k127_11634594_23 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000000000001297 136.0
DPH1_k127_11634594_24 Putative small multi-drug export protein - - - 0.000000000000000000000000000001237 126.0
DPH1_k127_11634594_25 PRC-barrel domain - - - 0.000000000000001059 79.0
DPH1_k127_11634594_26 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000003087 70.0
DPH1_k127_11634594_27 - - - - 0.00000003811 61.0
DPH1_k127_11634594_28 - - - - 0.0000003634 59.0
DPH1_k127_11634594_29 Bacterial PH domain - - - 0.00008133 54.0
DPH1_k127_11634594_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 584.0
DPH1_k127_11634594_30 nucleic acid binding OB-fold tRNA helicase-type - - - 0.00009486 53.0
DPH1_k127_11634594_4 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 456.0
DPH1_k127_11634594_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 413.0
DPH1_k127_11634594_6 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 364.0
DPH1_k127_11634594_7 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 314.0
DPH1_k127_11634594_8 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 306.0
DPH1_k127_11634594_9 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004945 286.0
DPH1_k127_11738884_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.257e-197 624.0
DPH1_k127_11738884_1 PHP C-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 435.0
DPH1_k127_11738884_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000001211 166.0
DPH1_k127_11738884_3 - - - - 0.0000000000001911 83.0
DPH1_k127_11876683_0 atp-citrate synthase subunit 1 K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 3.472e-196 620.0
DPH1_k127_11876683_1 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000008559 148.0
DPH1_k127_11876683_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000001124 123.0
DPH1_k127_12012872_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 7.145e-199 629.0
DPH1_k127_12012872_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 481.0
DPH1_k127_12012872_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001708 259.0
DPH1_k127_12012872_3 HhH-GPD family K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000003742 238.0
DPH1_k127_12012872_4 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000006601 227.0
DPH1_k127_12012872_5 PKD domain K19668 - 3.2.1.91 0.0000000003373 73.0
DPH1_k127_12012872_6 COG3209 Rhs family protein - - - 0.0005538 52.0
DPH1_k127_12015188_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 480.0
DPH1_k127_12015188_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 300.0
DPH1_k127_12015188_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
DPH1_k127_12015188_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001504 211.0
DPH1_k127_12015188_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000005936 202.0
DPH1_k127_12015188_5 DsrE/DsrF-like family K04085 - - 0.0000000000000000000000000000004061 125.0
DPH1_k127_12015188_6 4Fe-4S dicluster domain K11473 - - 0.000000000000000003275 97.0
DPH1_k127_12015188_7 pectinesterase activity - - - 0.0000002669 61.0
DPH1_k127_1474935_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.207e-293 927.0
DPH1_k127_1474935_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 5.516e-204 654.0
DPH1_k127_1474935_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 511.0
DPH1_k127_1474935_3 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000001144 188.0
DPH1_k127_1474935_4 Right handed beta helix region - - - 0.0000000000000000008321 99.0
DPH1_k127_1474935_5 Periplasmic copper-binding protein (NosD) - - - 0.00000000000009089 83.0
DPH1_k127_1474935_6 metallopeptidase activity - - - 0.00000000001941 74.0
DPH1_k127_1513809_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001892 285.0
DPH1_k127_1513809_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002272 258.0
DPH1_k127_1513809_2 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000001233 151.0
DPH1_k127_1513809_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000004884 143.0
DPH1_k127_1513809_4 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000005084 91.0
DPH1_k127_1513809_5 Peptidase family C25 - - - 0.000000005288 68.0
DPH1_k127_1513809_6 helix_turn_helix ASNC type K03719 - - 0.00002216 53.0
DPH1_k127_153322_0 - K03561,K12287 - - 0.0000000000000000000000000000000000000000000354 184.0
DPH1_k127_153322_1 PFAM Fibronectin, type III domain - - - 0.00003535 57.0
DPH1_k127_166824_0 Aromatic amino acid lyase K01745 - 4.3.1.3 9.782e-265 823.0
DPH1_k127_166824_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.14e-228 720.0
DPH1_k127_166824_10 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000001864 132.0
DPH1_k127_166824_11 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.000000000000000000000000000002556 136.0
DPH1_k127_166824_12 snRNP Sm proteins K04796 - - 0.000000000000000005796 86.0
DPH1_k127_166824_13 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000000000001482 85.0
DPH1_k127_166824_14 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000002025 77.0
DPH1_k127_166824_15 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.00000004017 66.0
DPH1_k127_166824_16 PFAM PKD domain containing protein K07004 - - 0.0003111 52.0
DPH1_k127_166824_2 DUF3160 - - - 6.353e-210 674.0
DPH1_k127_166824_3 Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 469.0
DPH1_k127_166824_4 TIGRFAM Small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 403.0
DPH1_k127_166824_5 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 328.0
DPH1_k127_166824_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003248 264.0
DPH1_k127_166824_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
DPH1_k127_166824_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
DPH1_k127_166824_9 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000005721 214.0
DPH1_k127_1973688_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.96e-208 668.0
DPH1_k127_1973688_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 610.0
DPH1_k127_1973688_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 415.0
DPH1_k127_1973688_3 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000001439 220.0
DPH1_k127_1973688_4 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.0000000000000000000000000000000000000000000000724 177.0
DPH1_k127_1973688_5 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000006773 87.0
DPH1_k127_1986028_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 556.0
DPH1_k127_1986028_1 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 488.0
DPH1_k127_1986028_2 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009412 267.0
DPH1_k127_1986028_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
DPH1_k127_1986028_4 Hydrogenase maturation protease K03605 - - 0.0000007448 53.0
DPH1_k127_2011664_0 COG3291 FOG PKD repeat K01387 GO:0005575,GO:0005576 3.4.24.3 0.000001631 61.0
DPH1_k127_2011664_1 alginic acid biosynthetic process - - - 0.00001116 57.0
DPH1_k127_2159057_0 KH, type 1, domain K07041 - - 6.785e-262 820.0
DPH1_k127_2159057_1 helicase superfamily c-terminal domain K03724 - - 7.393e-258 825.0
DPH1_k127_2159057_10 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
DPH1_k127_2159057_11 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 300.0
DPH1_k127_2159057_12 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006452 281.0
DPH1_k127_2159057_13 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 273.0
DPH1_k127_2159057_14 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000006617 236.0
DPH1_k127_2159057_15 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000004171 204.0
DPH1_k127_2159057_16 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000000000000000003365 198.0
DPH1_k127_2159057_17 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000000000000000000000000000004952 189.0
DPH1_k127_2159057_18 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000005677 162.0
DPH1_k127_2159057_19 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000002026 106.0
DPH1_k127_2159057_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.256e-229 718.0
DPH1_k127_2159057_20 - - - - 0.0000000003441 64.0
DPH1_k127_2159057_21 PFAM GCN5-related N-acetyltransferase - - - 0.000000007655 64.0
DPH1_k127_2159057_22 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000924 48.0
DPH1_k127_2159057_3 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 566.0
DPH1_k127_2159057_4 Proprotein convertase P-domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 555.0
DPH1_k127_2159057_5 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 482.0
DPH1_k127_2159057_6 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 451.0
DPH1_k127_2159057_7 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 438.0
DPH1_k127_2159057_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 416.0
DPH1_k127_2159057_9 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 398.0
DPH1_k127_2260737_0 flavodoxin nitric oxide synthase - - - 7.367e-201 631.0
DPH1_k127_2260737_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 428.0
DPH1_k127_2260737_2 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 341.0
DPH1_k127_2260737_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 317.0
DPH1_k127_2260737_4 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000006576 206.0
DPH1_k127_2260737_5 PFAM PKD domain containing protein - - - 0.00000000000008686 85.0
DPH1_k127_2291402_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 8.525e-234 738.0
DPH1_k127_2291402_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 441.0
DPH1_k127_2291402_10 Domain of unknown function (DUF2341) - - - 0.000000000002563 81.0
DPH1_k127_2291402_11 regulation of response to stimulus - - - 0.0000000002007 76.0
DPH1_k127_2291402_12 extracellular matrix structural constituent K02035 - - 0.0000002079 65.0
DPH1_k127_2291402_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001801 271.0
DPH1_k127_2291402_3 Chlorophyllase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000008578 232.0
DPH1_k127_2291402_4 ATP-binding region ATPase domain protein K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.000000000000000000000000000000000000000000000000000161 205.0
DPH1_k127_2291402_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000002428 191.0
DPH1_k127_2291402_6 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000004745 169.0
DPH1_k127_2291402_7 Fic/DOC family - - - 0.000000000000000000000000000000000000000002082 167.0
DPH1_k127_2291402_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000002555 92.0
DPH1_k127_2291402_9 outer membrane autotransporter barrel domain - - - 0.0000000000002821 84.0
DPH1_k127_2454074_0 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000001141 187.0
DPH1_k127_2454074_1 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000003123 103.0
DPH1_k127_2787205_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 466.0
DPH1_k127_2787205_1 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000005286 268.0
DPH1_k127_2787205_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000005012 75.0
DPH1_k127_2882803_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 1.889e-232 734.0
DPH1_k127_2882803_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 451.0
DPH1_k127_2882803_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 277.0
DPH1_k127_2882803_3 Chlorophyllase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000009141 248.0
DPH1_k127_2882803_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000002647 186.0
DPH1_k127_2882803_5 PFAM Protein kinase domain K00384,K03407,K11527 - 1.8.1.9,2.7.13.3 0.0000000000000000000000000000000000000000006246 176.0
DPH1_k127_2882803_6 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000001024 162.0
DPH1_k127_2882803_7 outer membrane autotransporter barrel domain - - - 0.0000000002082 75.0
DPH1_k127_2882803_8 Ig domain protein group 2 domain protein - - - 0.0003493 54.0
DPH1_k127_3058311_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000002266 224.0
DPH1_k127_3058311_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000005361 200.0
DPH1_k127_3058311_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000001019 119.0
DPH1_k127_308349_0 aminopeptidase K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 426.0
DPH1_k127_308349_1 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000004904 145.0
DPH1_k127_308349_2 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000000000414 113.0
DPH1_k127_308349_3 Papain family cysteine protease - - - 0.0000000000000000000000005901 121.0
DPH1_k127_308349_4 Sugar (and other) transporter K08196 - - 0.00000000006195 74.0
DPH1_k127_308349_5 PFAM periplasmic copper-binding - - - 0.00000001117 68.0
DPH1_k127_3087997_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 428.0
DPH1_k127_3087997_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 429.0
DPH1_k127_3087997_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 327.0
DPH1_k127_3087997_3 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 304.0
DPH1_k127_3087997_4 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000007016 188.0
DPH1_k127_3087997_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000005589 76.0
DPH1_k127_3087997_6 COG1520 FOG WD40-like repeat - - - 0.00000000000002723 86.0
DPH1_k127_3087997_7 ribosomal small subunit binding - - - 0.0002231 53.0
DPH1_k127_3653375_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 2.358e-203 653.0
DPH1_k127_3653375_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 508.0
DPH1_k127_3653375_2 cell wall organization - - - 0.00000000000002208 81.0
DPH1_k127_3653375_3 Papain family cysteine protease - - - 0.00000000000003105 79.0
DPH1_k127_3679162_0 - K03561,K12287 - - 0.000000000000000000000000000000000000000000001516 188.0
DPH1_k127_3679162_1 cell wall organization - - - 0.00000000002896 74.0
DPH1_k127_3778672_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 479.0
DPH1_k127_3778672_1 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 338.0
DPH1_k127_3930991_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 454.0
DPH1_k127_3930991_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 324.0
DPH1_k127_3930991_2 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000001801 147.0
DPH1_k127_4519787_0 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 300.0
DPH1_k127_4519787_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000002501 134.0
DPH1_k127_4519787_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000186 119.0
DPH1_k127_4530320_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.057e-213 694.0
DPH1_k127_4530320_1 tRNA binding K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 494.0
DPH1_k127_4530320_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000009034 58.0
DPH1_k127_4530320_11 ASPIC and UnbV - - - 0.000537 52.0
DPH1_k127_4530320_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 431.0
DPH1_k127_4530320_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 382.0
DPH1_k127_4530320_4 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 346.0
DPH1_k127_4530320_5 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
DPH1_k127_4530320_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000001846 204.0
DPH1_k127_4530320_7 PFAM Fibronectin type III domain - - - 0.0000000000000000000000000000001732 142.0
DPH1_k127_4530320_8 but it may be involved in stabilization of the trimeric complex - - - 0.0000004498 53.0
DPH1_k127_4530320_9 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.000001657 51.0
DPH1_k127_4903766_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
DPH1_k127_4903766_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001041 236.0
DPH1_k127_4903766_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000009263 48.0
DPH1_k127_4908351_0 Heavy-metal-associated domain K17686 - 3.6.3.54 6.443e-277 874.0
DPH1_k127_4908351_1 Belongs to the TPP enzyme family K00158 - 1.2.3.3 1.943e-221 698.0
DPH1_k127_4908351_10 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000003274 210.0
DPH1_k127_4908351_11 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000002301 170.0
DPH1_k127_4908351_12 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000006622 165.0
DPH1_k127_4908351_13 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000007559 134.0
DPH1_k127_4908351_14 COG0517 FOG CBS domain - - - 0.0000000000000000000000006507 117.0
DPH1_k127_4908351_15 phosphorelay signal transduction system K07658 - - 0.0000000000000000000002198 104.0
DPH1_k127_4908351_16 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000651 89.0
DPH1_k127_4908351_17 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000001215 103.0
DPH1_k127_4908351_18 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000005036 78.0
DPH1_k127_4908351_19 Major facilitator Superfamily K08162,K08226,K16211 - - 0.0000000000009453 80.0
DPH1_k127_4908351_2 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 376.0
DPH1_k127_4908351_20 membrane-associated protein domain - - - 0.0000000000427 74.0
DPH1_k127_4908351_21 Sterol carrier protein - - - 0.0000000004792 65.0
DPH1_k127_4908351_22 cell adhesion involved in biofilm formation - - - 0.00000003878 65.0
DPH1_k127_4908351_23 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000004393 63.0
DPH1_k127_4908351_24 TIGRFAM lycopene cyclase domain - - - 0.000001546 54.0
DPH1_k127_4908351_25 COG1522 Transcriptional regulators - - - 0.000002712 59.0
DPH1_k127_4908351_3 Protein of unknown function (DUF3887) K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 366.0
DPH1_k127_4908351_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 345.0
DPH1_k127_4908351_5 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 310.0
DPH1_k127_4908351_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 300.0
DPH1_k127_4908351_7 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 293.0
DPH1_k127_4908351_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000005081 254.0
DPH1_k127_4908351_9 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003035 241.0
DPH1_k127_5139255_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 363.0
DPH1_k127_5139255_1 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 352.0
DPH1_k127_5139255_2 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000002186 125.0
DPH1_k127_5139255_3 PFAM Circadian clock protein KaiC - - - 0.0000000000000000000000001083 116.0
DPH1_k127_5139255_4 L-fuculose phosphate aldolase K01628 - 4.1.2.17 0.00000776 55.0
DPH1_k127_5198834_0 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 343.0
DPH1_k127_5198834_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000002756 275.0
DPH1_k127_5198834_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006739 275.0
DPH1_k127_5198834_3 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.00000005938 68.0
DPH1_k127_5198834_4 HemY domain protein K20276 - - 0.0000002344 66.0
DPH1_k127_5333217_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000001552 237.0
DPH1_k127_5333217_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001208 225.0
DPH1_k127_5333217_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000002407 177.0
DPH1_k127_5333217_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000002122 121.0
DPH1_k127_5370780_0 COG0058 Glucan phosphorylase - - - 6.329e-222 702.0
DPH1_k127_5370780_1 Glycogen debranching enzyme N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 476.0
DPH1_k127_5370780_2 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 424.0
DPH1_k127_5370780_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 372.0
DPH1_k127_5370780_4 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000001093 90.0
DPH1_k127_5370780_5 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000004558 89.0
DPH1_k127_5775394_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001612 241.0
DPH1_k127_5775394_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000295 247.0
DPH1_k127_5775394_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000000001579 205.0
DPH1_k127_5775394_3 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000982 104.0
DPH1_k127_5775394_4 methyl-accepting chemotaxis protein K03406 - - 0.0000007311 57.0
DPH1_k127_5788580_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000005214 220.0
DPH1_k127_5788580_1 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000000000000000000000002135 139.0
DPH1_k127_5788580_2 MMPL family K07003 - - 0.0000000000000000000000001837 119.0
DPH1_k127_5788580_3 PFAM Transcriptional regulator TrmB - - - 0.0000000000000000000682 94.0
DPH1_k127_5788580_4 Protein of unknown function (DUF357) K09728 - - 0.0000000000001477 76.0
DPH1_k127_5788580_5 alpha-L-arabinofuranosidase - - - 0.0000000000003417 77.0
DPH1_k127_5972420_0 Circadian clock protein KaiC central region K08482 - - 0.00000000000000000000001991 111.0
DPH1_k127_5972420_1 PFAM PKD domain containing protein - - - 0.000000000000000001175 96.0
DPH1_k127_5972420_2 filamentous hemagglutinin family N-terminal domain - - - 0.000008574 59.0
DPH1_k127_5972420_3 Fibronectin type 3 domain K01637 - 4.1.3.1 0.0001033 55.0
DPH1_k127_59793_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 393.0
DPH1_k127_59793_1 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000955 193.0
DPH1_k127_59793_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000000001681 84.0
DPH1_k127_6034947_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 482.0
DPH1_k127_6034947_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 468.0
DPH1_k127_6034947_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007501 256.0
DPH1_k127_6034947_11 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 255.0
DPH1_k127_6034947_12 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000001042 198.0
DPH1_k127_6034947_13 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000001126 188.0
DPH1_k127_6034947_14 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.000000000000000000000000000000003445 136.0
DPH1_k127_6034947_15 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000005166 126.0
DPH1_k127_6034947_16 cluster protein-associated redox disulfide domain - - - 0.000000000000001868 78.0
DPH1_k127_6034947_17 dihydrofolate synthase activity K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.000158 45.0
DPH1_k127_6034947_18 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0003691 48.0
DPH1_k127_6034947_2 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 466.0
DPH1_k127_6034947_3 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 446.0
DPH1_k127_6034947_4 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 432.0
DPH1_k127_6034947_5 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 327.0
DPH1_k127_6034947_6 Clp protease K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 330.0
DPH1_k127_6034947_7 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
DPH1_k127_6034947_8 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 289.0
DPH1_k127_6034947_9 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000002419 259.0
DPH1_k127_612189_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.682e-211 674.0
DPH1_k127_612189_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.818e-198 625.0
DPH1_k127_612189_10 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
DPH1_k127_612189_11 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 244.0
DPH1_k127_612189_12 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000001332 201.0
DPH1_k127_612189_13 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000003001 186.0
DPH1_k127_612189_14 regulator of amino acid metabolism K07103 - - 0.0000000000000000000000000000000000001671 148.0
DPH1_k127_612189_15 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000002797 126.0
DPH1_k127_612189_16 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000000005561 118.0
DPH1_k127_612189_17 - - - - 0.0000000000000000000002633 97.0
DPH1_k127_612189_18 secreted hydrolase - - - 0.0000000000000000000278 102.0
DPH1_k127_612189_19 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000007111 81.0
DPH1_k127_612189_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 563.0
DPH1_k127_612189_20 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 0.0000000007867 67.0
DPH1_k127_612189_21 - - - - 0.00000003119 59.0
DPH1_k127_612189_22 Peptidase family C25 - - - 0.0000003331 63.0
DPH1_k127_612189_3 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 535.0
DPH1_k127_612189_4 RmlD substrate binding domain K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 509.0
DPH1_k127_612189_5 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 435.0
DPH1_k127_612189_6 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 392.0
DPH1_k127_612189_7 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007371 286.0
DPH1_k127_612189_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000821 269.0
DPH1_k127_612189_9 Patched family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007913 281.0
DPH1_k127_6175379_0 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001439 231.0
DPH1_k127_6175379_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000005767 113.0
DPH1_k127_6175379_2 Right handed beta helix region - - - 0.000004857 57.0
DPH1_k127_6175379_3 domain protein K20276 - - 0.00001739 51.0
DPH1_k127_6177811_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004855 273.0
DPH1_k127_6177811_1 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.000000000000000000000000000000005707 134.0
DPH1_k127_6177811_2 amine dehydrogenase activity - - - 0.000000000000001344 89.0
DPH1_k127_62368_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 7.842e-272 857.0
DPH1_k127_62368_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 616.0
DPH1_k127_62368_10 Belongs to the UPF0200 family - - - 0.0000000000000000000000000000000000000000000000004351 181.0
DPH1_k127_62368_11 Pas domain - - - 0.000000000000000000000000000000000000000000003794 175.0
DPH1_k127_62368_12 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000002548 168.0
DPH1_k127_62368_13 cyclopropane-fatty-acyl-phospholipid synthase K20444 - - 0.000000000000000000003555 106.0
DPH1_k127_62368_14 response regulator, receiver K07668,K07669 - - 0.000000000000000000005957 97.0
DPH1_k127_62368_15 Peptidase, M28 - - - 0.000000000000000000009578 106.0
DPH1_k127_62368_16 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000001603 93.0
DPH1_k127_62368_17 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00008388 55.0
DPH1_k127_62368_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 414.0
DPH1_k127_62368_3 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 380.0
DPH1_k127_62368_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 368.0
DPH1_k127_62368_5 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002861 273.0
DPH1_k127_62368_6 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000002911 234.0
DPH1_k127_62368_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000001596 229.0
DPH1_k127_62368_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000002076 220.0
DPH1_k127_62368_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000004406 221.0
DPH1_k127_6425623_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 585.0
DPH1_k127_6425623_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 314.0
DPH1_k127_6425623_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000149 137.0
DPH1_k127_6425623_3 aminopeptidase activity K05994 - 3.4.11.10 0.00000000000000000000000006145 122.0
DPH1_k127_6425623_4 Propeptide_C25 - - - 0.000000000001576 81.0
DPH1_k127_6425623_5 Lrp/AsnC ligand binding domain - - - 0.000000006327 59.0
DPH1_k127_6425623_6 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.000000006969 69.0
DPH1_k127_6425623_7 helix_turn_helix ASNC type K03719 - - 0.0000008589 57.0
DPH1_k127_6425623_8 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.000002494 52.0
DPH1_k127_6596664_0 Pentaxin family K12287 - - 0.000000005835 70.0
DPH1_k127_6596664_1 pathogenesis K13669 - - 0.00000006972 66.0
DPH1_k127_6596664_2 Lamin Tail Domain - - - 0.0000004799 64.0
DPH1_k127_6731965_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 538.0
DPH1_k127_6731965_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 556.0
DPH1_k127_6731965_10 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 329.0
DPH1_k127_6731965_11 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 310.0
DPH1_k127_6731965_12 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004406 293.0
DPH1_k127_6731965_13 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005729 276.0
DPH1_k127_6731965_14 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001489 274.0
DPH1_k127_6731965_15 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005955 269.0
DPH1_k127_6731965_16 GHMP kinases C terminal K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000005352 262.0
DPH1_k127_6731965_17 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001132 263.0
DPH1_k127_6731965_18 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000006342 254.0
DPH1_k127_6731965_19 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000004072 234.0
DPH1_k127_6731965_2 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 535.0
DPH1_k127_6731965_20 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000001144 224.0
DPH1_k127_6731965_21 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000002656 221.0
DPH1_k127_6731965_22 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000001885 199.0
DPH1_k127_6731965_23 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000007661 188.0
DPH1_k127_6731965_24 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000004361 194.0
DPH1_k127_6731965_25 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000008118 193.0
DPH1_k127_6731965_26 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.000000000000000000000000000000000000000000000648 178.0
DPH1_k127_6731965_27 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000001055 168.0
DPH1_k127_6731965_28 Male sterility protein - - - 0.00000000000000000000000000000000000000004356 164.0
DPH1_k127_6731965_29 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000001322 153.0
DPH1_k127_6731965_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 500.0
DPH1_k127_6731965_30 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000001199 138.0
DPH1_k127_6731965_31 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000006163 123.0
DPH1_k127_6731965_32 Transcriptional regulator, TrmB - - - 0.00000000000000000000000001748 113.0
DPH1_k127_6731965_33 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000234 110.0
DPH1_k127_6731965_34 PQ loop repeat K15383 - - 0.0000000000000000001547 91.0
DPH1_k127_6731965_35 - - - - 0.000000000001366 71.0
DPH1_k127_6731965_36 Methyltransferase domain - - - 0.000000000002048 74.0
DPH1_k127_6731965_37 Nicotianamine synthase protein - - - 0.00000000009771 70.0
DPH1_k127_6731965_38 Radical SAM - - - 0.0000000008367 70.0
DPH1_k127_6731965_39 - - - - 0.0000002157 54.0
DPH1_k127_6731965_4 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 496.0
DPH1_k127_6731965_40 Lipocalin-like domain - - - 0.0000004541 62.0
DPH1_k127_6731965_41 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000002273 59.0
DPH1_k127_6731965_42 - - - - 0.00000695 52.0
DPH1_k127_6731965_5 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 495.0
DPH1_k127_6731965_6 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 466.0
DPH1_k127_6731965_7 resolution of meiotic recombination intermediates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 478.0
DPH1_k127_6731965_8 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 451.0
DPH1_k127_6731965_9 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 350.0
DPH1_k127_6741396_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1590.0
DPH1_k127_6741396_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 595.0
DPH1_k127_6741396_10 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000009482 228.0
DPH1_k127_6741396_11 PFAM HD domain K03698 - - 0.000000000000000000000000000000000000000000000000000000000001845 222.0
DPH1_k127_6741396_12 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000001191 192.0
DPH1_k127_6741396_13 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000000000000000134 190.0
DPH1_k127_6741396_14 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000000000251 186.0
DPH1_k127_6741396_15 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000003624 164.0
DPH1_k127_6741396_16 phosphoesterase RecJ domain protein - - - 0.000000000000000000000000000000000000008616 158.0
DPH1_k127_6741396_17 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000004779 138.0
DPH1_k127_6741396_18 ArsR transcriptional regulator - - - 0.00000000000000000000000000000002759 132.0
DPH1_k127_6741396_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000137 128.0
DPH1_k127_6741396_2 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 536.0
DPH1_k127_6741396_20 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000001456 122.0
DPH1_k127_6741396_21 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000005111 106.0
DPH1_k127_6741396_22 Integral membrane protein DUF106 - - - 0.00000000000000000000000893 109.0
DPH1_k127_6741396_23 Conserved repeat domain - - - 0.000000000000000001684 96.0
DPH1_k127_6741396_24 Trm112p-like protein - - - 0.0000000000000002456 79.0
DPH1_k127_6741396_25 Domain of unknown function (DUF4382) - - - 0.00000000000003868 82.0
DPH1_k127_6741396_26 Domain of unknown function (DUF4382) - - - 0.00000000001491 72.0
DPH1_k127_6741396_27 Domain of unknown function DUF11 - - - 0.00000000001616 78.0
DPH1_k127_6741396_28 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000007542 63.0
DPH1_k127_6741396_3 HELICc2 K03722,K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 441.0
DPH1_k127_6741396_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 381.0
DPH1_k127_6741396_5 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 371.0
DPH1_k127_6741396_6 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 373.0
DPH1_k127_6741396_7 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 362.0
DPH1_k127_6741396_8 Leucine rich repeats (6 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 310.0
DPH1_k127_6741396_9 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001146 225.0
DPH1_k127_6757077_0 KH, type 1, domain K07041 - - 2.151e-260 816.0
DPH1_k127_6757077_1 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 444.0
DPH1_k127_6757077_10 endonuclease III K07457 - - 0.00009202 45.0
DPH1_k127_6757077_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 416.0
DPH1_k127_6757077_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 302.0
DPH1_k127_6757077_4 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
DPH1_k127_6757077_5 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000175 273.0
DPH1_k127_6757077_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000002837 240.0
DPH1_k127_6757077_7 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000003509 196.0
DPH1_k127_6757077_8 Right handed beta helix region - - - 0.000000000000000000000000003791 128.0
DPH1_k127_6757077_9 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000000457 55.0
DPH1_k127_6968476_0 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 340.0
DPH1_k127_6968476_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 253.0
DPH1_k127_6968476_2 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 243.0
DPH1_k127_6968476_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000002307 173.0
DPH1_k127_6968476_4 Cupin 2, conserved barrel domain protein K09988 - 5.3.1.15 0.00000000000000000000000000000000000000000000003308 173.0
DPH1_k127_6968476_5 Cupin domain - - - 0.0000000000000000000000000000004556 127.0
DPH1_k127_6968476_6 Propeptide_C25 - - - 0.000000000000004776 89.0
DPH1_k127_7066072_0 Psort location Extracellular, score 9.64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001772 298.0
DPH1_k127_7066072_1 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000001239 250.0
DPH1_k127_7066072_2 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000002082 134.0
DPH1_k127_7066072_3 Fibronectin type 3 domain K20276 - - 0.0000000000000000000000000009851 124.0
DPH1_k127_7066072_4 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002139 113.0
DPH1_k127_7066072_5 F5/8 type C domain - - - 0.000002405 60.0
DPH1_k127_7066072_6 - - - - 0.000007783 52.0
DPH1_k127_7243793_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 413.0
DPH1_k127_7243793_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 331.0
DPH1_k127_7243793_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006514 246.0
DPH1_k127_7243793_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000002649 179.0
DPH1_k127_7243793_4 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002004 132.0
DPH1_k127_7243793_5 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000004723 91.0
DPH1_k127_7243793_6 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000000000000005464 100.0
DPH1_k127_7243793_7 Binds to the 23S rRNA K02922 - - 0.00000000000007646 72.0
DPH1_k127_7243793_8 Conserved repeat domain - - - 0.000000000002831 79.0
DPH1_k127_7243793_9 Uncharacterised protein family (UPF0227) K07000 - - 0.00000001146 64.0
DPH1_k127_7490662_0 Oxidoreductase family, C-terminal alpha beta domain K13016 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 447.0
DPH1_k127_7490662_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 392.0
DPH1_k127_7490662_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 376.0
DPH1_k127_7490662_3 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001047 225.0
DPH1_k127_7490662_4 Succinoglycan biosynthesis protein exoa - - - 0.0000000000000000000000000000000000000001153 163.0
DPH1_k127_7490662_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000001534 61.0
DPH1_k127_7591415_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1110.0
DPH1_k127_7591415_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1098.0
DPH1_k127_7591415_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 431.0
DPH1_k127_7591415_11 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 355.0
DPH1_k127_7591415_12 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 344.0
DPH1_k127_7591415_13 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 331.0
DPH1_k127_7591415_14 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 327.0
DPH1_k127_7591415_15 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 322.0
DPH1_k127_7591415_16 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 316.0
DPH1_k127_7591415_17 by modhmm K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 306.0
DPH1_k127_7591415_18 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 274.0
DPH1_k127_7591415_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000007916 242.0
DPH1_k127_7591415_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 3.41e-235 741.0
DPH1_k127_7591415_20 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000008771 242.0
DPH1_k127_7591415_21 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000002678 247.0
DPH1_k127_7591415_22 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000358 226.0
DPH1_k127_7591415_23 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
DPH1_k127_7591415_24 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000002288 230.0
DPH1_k127_7591415_25 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000002942 224.0
DPH1_k127_7591415_26 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000001674 221.0
DPH1_k127_7591415_27 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000004532 211.0
DPH1_k127_7591415_28 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000008996 218.0
DPH1_k127_7591415_29 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000009389 208.0
DPH1_k127_7591415_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.294e-226 708.0
DPH1_k127_7591415_30 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000002846 200.0
DPH1_k127_7591415_31 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000002238 195.0
DPH1_k127_7591415_32 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
DPH1_k127_7591415_33 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000002057 187.0
DPH1_k127_7591415_34 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000000003986 179.0
DPH1_k127_7591415_35 Lysine exporter protein LysE YggA - - - 0.00000000000000000000000000000000000004365 150.0
DPH1_k127_7591415_36 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000005326 150.0
DPH1_k127_7591415_37 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000002116 147.0
DPH1_k127_7591415_38 - - - - 0.00000000000000000000000000000000001717 141.0
DPH1_k127_7591415_39 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001841 130.0
DPH1_k127_7591415_4 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 3.231e-211 671.0
DPH1_k127_7591415_40 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000009203 124.0
DPH1_k127_7591415_41 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000001799 113.0
DPH1_k127_7591415_42 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000008156 97.0
DPH1_k127_7591415_43 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000001319 98.0
DPH1_k127_7591415_44 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000003398 97.0
DPH1_k127_7591415_45 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000001441 107.0
DPH1_k127_7591415_46 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000153 93.0
DPH1_k127_7591415_47 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.00000000000000001435 89.0
DPH1_k127_7591415_48 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000001955 86.0
DPH1_k127_7591415_49 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000002745 87.0
DPH1_k127_7591415_5 DEAD DEAH box helicase domain protein K10896 - - 2.844e-200 648.0
DPH1_k127_7591415_50 PFAM NHL repeat containing protein - - - 0.000000000000009236 88.0
DPH1_k127_7591415_51 parallel beta-helix repeat - - - 0.00000000000001914 85.0
DPH1_k127_7591415_52 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000002991 76.0
DPH1_k127_7591415_53 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000004592 72.0
DPH1_k127_7591415_54 PFAM PKD domain containing protein - - - 0.000000005627 69.0
DPH1_k127_7591415_55 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000214 60.0
DPH1_k127_7591415_56 COG1522 Transcriptional regulators K03718 - - 0.00000003091 59.0
DPH1_k127_7591415_58 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000001625 53.0
DPH1_k127_7591415_59 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000003645 59.0
DPH1_k127_7591415_6 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 9.492e-197 623.0
DPH1_k127_7591415_60 - - - - 0.000004515 58.0
DPH1_k127_7591415_61 COG1522 Transcriptional regulators - - - 0.00001955 52.0
DPH1_k127_7591415_62 H subunit K02107 - - 0.00006204 50.0
DPH1_k127_7591415_63 CAAX protease self-immunity K07052 - - 0.0001439 52.0
DPH1_k127_7591415_7 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 482.0
DPH1_k127_7591415_8 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 463.0
DPH1_k127_7591415_9 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 454.0
DPH1_k127_7675720_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 516.0
DPH1_k127_7675720_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 503.0
DPH1_k127_7675720_10 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000004559 201.0
DPH1_k127_7675720_11 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.000000000000000000000000000000000000000000000000000006801 191.0
DPH1_k127_7675720_12 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000002552 189.0
DPH1_k127_7675720_13 - K07092 - - 0.0000000000000000000000000000000000000000000000003256 177.0
DPH1_k127_7675720_14 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000003289 179.0
DPH1_k127_7675720_15 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000000006036 158.0
DPH1_k127_7675720_16 Rubrerythrin - - - 0.00000000000000000000000000000000000002654 149.0
DPH1_k127_7675720_17 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000002062 126.0
DPH1_k127_7675720_18 Belongs to the Fur family K09825 - - 0.00000000000000000000000002206 113.0
DPH1_k127_7675720_19 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000006868 107.0
DPH1_k127_7675720_2 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 460.0
DPH1_k127_7675720_20 protein conserved in archaea - - - 0.0000000000000000001601 91.0
DPH1_k127_7675720_22 - K03741 - 1.20.4.1 0.000000000001889 71.0
DPH1_k127_7675720_23 collagenase K01387 - 3.4.24.3 0.000000000689 70.0
DPH1_k127_7675720_24 FIST_C - - - 0.000000323 63.0
DPH1_k127_7675720_25 Peptidase family C25 - - - 0.000004178 60.0
DPH1_k127_7675720_26 membrane-associated protein domain - - - 0.00002792 57.0
DPH1_k127_7675720_27 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02396 - - 0.00002792 57.0
DPH1_k127_7675720_3 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 347.0
DPH1_k127_7675720_4 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 300.0
DPH1_k127_7675720_5 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 306.0
DPH1_k127_7675720_6 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 300.0
DPH1_k127_7675720_7 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 281.0
DPH1_k127_7675720_8 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003404 273.0
DPH1_k127_7675720_9 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000004341 222.0
DPH1_k127_8025363_0 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 550.0
DPH1_k127_8025363_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 488.0
DPH1_k127_8025363_10 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.0000000000000000000000004642 118.0
DPH1_k127_8025363_11 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000001015 102.0
DPH1_k127_8025363_12 Domain of unknown function (DUF4314) - - - 0.00000006674 57.0
DPH1_k127_8025363_13 PFAM UvrD REP helicase - - - 0.0000004147 56.0
DPH1_k127_8025363_14 - - - - 0.0000008305 54.0
DPH1_k127_8025363_15 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001619 53.0
DPH1_k127_8025363_2 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 395.0
DPH1_k127_8025363_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 351.0
DPH1_k127_8025363_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 328.0
DPH1_k127_8025363_5 Penicillin acylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 339.0
DPH1_k127_8025363_6 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006685 245.0
DPH1_k127_8025363_7 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000002583 232.0
DPH1_k127_8025363_8 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000000009776 207.0
DPH1_k127_8025363_9 transcriptional - - - 0.0000000000000000000000000001029 119.0
DPH1_k127_80749_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.498e-311 975.0
DPH1_k127_80749_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 5.957e-257 801.0
DPH1_k127_80749_10 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 416.0
DPH1_k127_80749_11 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 357.0
DPH1_k127_80749_12 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 300.0
DPH1_k127_80749_13 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000383 295.0
DPH1_k127_80749_14 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007077 288.0
DPH1_k127_80749_15 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000004444 243.0
DPH1_k127_80749_16 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000001109 228.0
DPH1_k127_80749_17 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001005 210.0
DPH1_k127_80749_18 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000004045 202.0
DPH1_k127_80749_19 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000001818 203.0
DPH1_k127_80749_2 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.233e-252 788.0
DPH1_k127_80749_20 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000000009633 188.0
DPH1_k127_80749_21 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.000000000000000000000000000000000000000000000352 173.0
DPH1_k127_80749_22 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000388 125.0
DPH1_k127_80749_23 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000008871 135.0
DPH1_k127_80749_24 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000002815 111.0
DPH1_k127_80749_25 - - - - 0.0000000000000001152 85.0
DPH1_k127_80749_26 Nitroreductase family - - - 0.000000000000000435 91.0
DPH1_k127_80749_27 Hsp20/alpha crystallin family K13993 - - 0.000000000000001461 82.0
DPH1_k127_80749_28 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.000000000000003238 83.0
DPH1_k127_80749_29 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000001005 82.0
DPH1_k127_80749_3 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 1.944e-242 764.0
DPH1_k127_80749_30 Uncharacterised protein family UPF0058 - - - 0.00000006976 58.0
DPH1_k127_80749_31 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000001052 64.0
DPH1_k127_80749_32 PFAM response regulator receiver - - - 0.000003005 54.0
DPH1_k127_80749_33 Peptidase family C25 - - - 0.0000266 56.0
DPH1_k127_80749_34 Glycosyl hydrolases family 18 K01183 - 3.2.1.14 0.0002214 55.0
DPH1_k127_80749_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.934e-241 766.0
DPH1_k127_80749_5 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 603.0
DPH1_k127_80749_6 Biotin carboxylase K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 526.0
DPH1_k127_80749_7 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 459.0
DPH1_k127_80749_8 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 439.0
DPH1_k127_80749_9 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 438.0
DPH1_k127_8414568_0 Heat shock 70 kDa protein K04043 - - 3.016e-237 750.0
DPH1_k127_8414568_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 5.856e-221 698.0
DPH1_k127_8414568_2 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 492.0
DPH1_k127_8414568_3 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 416.0
DPH1_k127_8414568_4 Pfam:DUF552 K09152 - - 0.000000000000000000000001542 107.0
DPH1_k127_8414568_5 - - - - 0.0000000000000006298 84.0
DPH1_k127_8414568_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000002454 85.0
DPH1_k127_8414568_7 PFAM CBS domain containing protein K04767 - - 0.0000000000000582 77.0
DPH1_k127_8414568_8 Universal stress protein family - - - 0.000000000002235 73.0
DPH1_k127_8414568_9 sequence-specific DNA binding - - - 0.0002197 47.0
DPH1_k127_8417599_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1579.0
DPH1_k127_8417599_1 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.034e-266 850.0
DPH1_k127_8417599_10 PFAM Histone deacetylase K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000002556 233.0
DPH1_k127_8417599_11 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000004718 210.0
DPH1_k127_8417599_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000004437 209.0
DPH1_k127_8417599_13 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000005368 186.0
DPH1_k127_8417599_14 PFAM Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000005855 194.0
DPH1_k127_8417599_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000002935 189.0
DPH1_k127_8417599_16 pfam nmd3 K07562 - - 0.0000000000000000000000000000000000000000000004353 180.0
DPH1_k127_8417599_17 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000003958 175.0
DPH1_k127_8417599_18 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000008087 172.0
DPH1_k127_8417599_19 transcription regulator activity - - - 0.0000000000000000000000000000000000000001718 154.0
DPH1_k127_8417599_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.359e-217 696.0
DPH1_k127_8417599_20 spore germination K03605 - - 0.00000000000000000000000001547 114.0
DPH1_k127_8417599_21 Papain family cysteine protease - - - 0.000000000000000000000002548 115.0
DPH1_k127_8417599_22 peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000008235 107.0
DPH1_k127_8417599_23 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000141 96.0
DPH1_k127_8417599_24 Glycosyl transferase family 2 - - - 0.0000000000002923 78.0
DPH1_k127_8417599_26 - - - - 0.00000000001801 70.0
DPH1_k127_8417599_27 Acetyltransferase (GNAT) domain - - - 0.0000000002422 68.0
DPH1_k127_8417599_28 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000004722 64.0
DPH1_k127_8417599_29 PFAM NHL repeat containing protein - - - 0.0000004067 59.0
DPH1_k127_8417599_3 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 2.758e-198 629.0
DPH1_k127_8417599_30 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000001052 60.0
DPH1_k127_8417599_31 S-layer homology domain - - - 0.000002063 53.0
DPH1_k127_8417599_32 Phage integrase family - - - 0.000105 52.0
DPH1_k127_8417599_4 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 559.0
DPH1_k127_8417599_5 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 479.0
DPH1_k127_8417599_6 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 370.0
DPH1_k127_8417599_7 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 359.0
DPH1_k127_8417599_8 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 351.0
DPH1_k127_8417599_9 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007239 275.0
DPH1_k127_8486725_0 Psort location Cytoplasmic, score - - - 0.0 1392.0
DPH1_k127_8486725_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1172.0
DPH1_k127_8486725_10 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
DPH1_k127_8486725_11 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
DPH1_k127_8486725_12 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004051 278.0
DPH1_k127_8486725_13 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
DPH1_k127_8486725_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00125 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000008602 259.0
DPH1_k127_8486725_15 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
DPH1_k127_8486725_16 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000006295 227.0
DPH1_k127_8486725_17 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000006415 229.0
DPH1_k127_8486725_18 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000001792 220.0
DPH1_k127_8486725_19 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000004562 221.0
DPH1_k127_8486725_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 0.0 1168.0
DPH1_k127_8486725_20 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000001439 157.0
DPH1_k127_8486725_21 4Fe-4S binding domain - - - 0.000000000000000000000000000000000001264 143.0
DPH1_k127_8486725_22 Participates in transcription termination K02600 - - 0.000000000000000000000000000009143 123.0
DPH1_k127_8486725_23 binds to the 23S rRNA K02921 - - 0.0000000000000000000000002173 108.0
DPH1_k127_8486725_24 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000003863 106.0
DPH1_k127_8486725_25 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000002997 102.0
DPH1_k127_8486725_26 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000004581 104.0
DPH1_k127_8486725_27 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000001242 88.0
DPH1_k127_8486725_28 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000005653 87.0
DPH1_k127_8486725_29 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.00000000000001533 76.0
DPH1_k127_8486725_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1039.0
DPH1_k127_8486725_30 4Fe-4S dicluster domain - - - 0.000000000001403 76.0
DPH1_k127_8486725_31 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000009192 57.0
DPH1_k127_8486725_32 Transcription factor Pcc1 K09741 - - 0.000005466 51.0
DPH1_k127_8486725_33 related to archaeal Holliday junction resolvase - - - 0.000607 47.0
DPH1_k127_8486725_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.339e-210 673.0
DPH1_k127_8486725_5 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 609.0
DPH1_k127_8486725_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 469.0
DPH1_k127_8486725_7 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 472.0
DPH1_k127_8486725_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 409.0
DPH1_k127_8486725_9 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 337.0
DPH1_k127_8599625_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 575.0
DPH1_k127_8599625_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 456.0
DPH1_k127_8599625_10 Biotin-protein ligase, N terminal - - - 0.0000005633 62.0
DPH1_k127_8599625_11 PKD domain - - - 0.00003167 49.0
DPH1_k127_8599625_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000255 47.0
DPH1_k127_8599625_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000003154 253.0
DPH1_k127_8599625_3 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000002895 228.0
DPH1_k127_8599625_4 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000602 180.0
DPH1_k127_8599625_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000005552 151.0
DPH1_k127_8599625_6 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000001482 147.0
DPH1_k127_8599625_7 Sulfotransferase family - - - 0.0000000000000000000000000000000002684 136.0
DPH1_k127_8599625_8 protein conserved in archaea - - - 0.000000000000000001032 91.0
DPH1_k127_8599625_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000001429 72.0
DPH1_k127_8734552_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 480.0
DPH1_k127_8734552_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 355.0
DPH1_k127_8734552_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 276.0
DPH1_k127_8734552_11 Peptidase S9 prolyl oligopeptidase active site K01281 - 3.4.14.11 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 264.0
DPH1_k127_8734552_12 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000198 262.0
DPH1_k127_8734552_13 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000008219 217.0
DPH1_k127_8734552_14 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.000000000000000000000000000000000000000000000000008729 201.0
DPH1_k127_8734552_15 - - - - 0.0000000000000000000000000000000000000000000000692 170.0
DPH1_k127_8734552_16 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000005366 158.0
DPH1_k127_8734552_17 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000007878 159.0
DPH1_k127_8734552_18 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000002158 146.0
DPH1_k127_8734552_19 Papain family cysteine protease - - - 0.0000000000000000000000000000000000004771 154.0
DPH1_k127_8734552_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 354.0
DPH1_k127_8734552_20 Uncharacterised protein family (UPF0179) K09730 - - 0.000000000000000000000000000000000005281 141.0
DPH1_k127_8734552_21 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000000002665 139.0
DPH1_k127_8734552_22 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.0000000000000000000000000000007082 126.0
DPH1_k127_8734552_23 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000002556 121.0
DPH1_k127_8734552_24 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000316 117.0
DPH1_k127_8734552_25 - - - - 0.000000000000000000000009953 108.0
DPH1_k127_8734552_26 membrane - - - 0.00000000000000000000007742 111.0
DPH1_k127_8734552_27 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000003834 101.0
DPH1_k127_8734552_28 PFAM Ig domain protein group 2 domain protein - - - 0.000000000000000001484 102.0
DPH1_k127_8734552_29 cell adhesion involved in biofilm formation K02014,K11031 - - 0.000000000000000003392 101.0
DPH1_k127_8734552_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 339.0
DPH1_k127_8734552_30 Thioredoxin-like - - - 0.0000000000001164 79.0
DPH1_k127_8734552_31 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000002019 59.0
DPH1_k127_8734552_32 Bacterial lipoate protein ligase C-terminus K03800 - 6.3.1.20 0.0000002631 55.0
DPH1_k127_8734552_34 UbiA prenyltransferase family - - - 0.0002106 53.0
DPH1_k127_8734552_4 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 345.0
DPH1_k127_8734552_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 330.0
DPH1_k127_8734552_6 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 321.0
DPH1_k127_8734552_7 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 314.0
DPH1_k127_8734552_8 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 301.0
DPH1_k127_8734552_9 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001567 287.0
DPH1_k127_8844730_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 8.488e-311 966.0
DPH1_k127_8844730_1 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 496.0
DPH1_k127_8844730_10 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 333.0
DPH1_k127_8844730_11 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 317.0
DPH1_k127_8844730_12 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 323.0
DPH1_k127_8844730_13 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 310.0
DPH1_k127_8844730_14 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 315.0
DPH1_k127_8844730_15 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
DPH1_k127_8844730_16 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
DPH1_k127_8844730_17 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 298.0
DPH1_k127_8844730_18 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 300.0
DPH1_k127_8844730_19 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 288.0
DPH1_k127_8844730_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 471.0
DPH1_k127_8844730_20 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000478 303.0
DPH1_k127_8844730_21 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007279 287.0
DPH1_k127_8844730_22 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009277 267.0
DPH1_k127_8844730_23 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 267.0
DPH1_k127_8844730_24 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000233 266.0
DPH1_k127_8844730_25 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001231 267.0
DPH1_k127_8844730_26 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
DPH1_k127_8844730_27 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002684 263.0
DPH1_k127_8844730_28 Belongs to the complex I 20 kDa subunit family K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000004225 233.0
DPH1_k127_8844730_29 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
DPH1_k127_8844730_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 453.0
DPH1_k127_8844730_30 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
DPH1_k127_8844730_31 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000006783 216.0
DPH1_k127_8844730_32 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000001237 206.0
DPH1_k127_8844730_33 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000002425 198.0
DPH1_k127_8844730_34 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000003116 186.0
DPH1_k127_8844730_35 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000003494 182.0
DPH1_k127_8844730_36 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000001129 190.0
DPH1_k127_8844730_37 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000001667 185.0
DPH1_k127_8844730_38 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000001999 164.0
DPH1_k127_8844730_39 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.0000000000000000000000000000000000000000002994 161.0
DPH1_k127_8844730_4 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 426.0
DPH1_k127_8844730_40 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.00000000000000000000000000000000000000005113 158.0
DPH1_k127_8844730_41 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000009455 151.0
DPH1_k127_8844730_42 Belongs to the UPF0251 family - - - 0.00000000000000000000000000000004647 128.0
DPH1_k127_8844730_43 SMART Excinuclease ABC, C subunit - - - 0.0000000000000000000000000000002934 127.0
DPH1_k127_8844730_44 Mediates zinc uptake. May also transport other divalent cations K07238 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - 0.0000000000000000000000000000005482 131.0
DPH1_k127_8844730_45 hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000000000000000973 121.0
DPH1_k127_8844730_46 nitrogen fixation - - - 0.000000000000000000000008394 104.0
DPH1_k127_8844730_47 Divalent ion tolerance protein K03926 - - 0.0000000000000000000001715 100.0
DPH1_k127_8844730_48 PFAM glutaredoxin - - - 0.00000000000000000004326 93.0
DPH1_k127_8844730_49 Lrp/AsnC ligand binding domain - - - 0.00000000000000000005438 91.0
DPH1_k127_8844730_5 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 410.0
DPH1_k127_8844730_50 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.000000000000000001861 89.0
DPH1_k127_8844730_51 HAD-hyrolase-like - - - 0.000000000000000004842 93.0
DPH1_k127_8844730_52 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000138 87.0
DPH1_k127_8844730_53 PFAM regulatory protein, ArsR - - - 0.00000000000000003185 91.0
DPH1_k127_8844730_54 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000005929 81.0
DPH1_k127_8844730_55 Transcriptional regulator K07108 - - 0.0000000000000005129 81.0
DPH1_k127_8844730_56 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000005241 79.0
DPH1_k127_8844730_57 - - - - 0.0000000000001243 75.0
DPH1_k127_8844730_58 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000002213 73.0
DPH1_k127_8844730_59 Conserved repeat domain - - - 0.00000000000145 81.0
DPH1_k127_8844730_6 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 390.0
DPH1_k127_8844730_60 - - - - 0.0002392 48.0
DPH1_k127_8844730_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 370.0
DPH1_k127_8844730_8 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 361.0
DPH1_k127_8844730_9 TIGRFAM ribosomal RNA small subunit methyltransferase RsmB K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 355.0
DPH1_k127_885801_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 450.0
DPH1_k127_885801_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 347.0
DPH1_k127_885801_10 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000808 184.0
DPH1_k127_885801_11 NUDIX domain - - - 0.0000000000000000000000000000000000008232 143.0
DPH1_k127_885801_12 AraC-like ligand binding domain - - - 0.00000000000000000000000000000003881 128.0
DPH1_k127_885801_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000005738 134.0
DPH1_k127_885801_14 - - - - 0.00000000000000000000000005029 113.0
DPH1_k127_885801_15 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000369 83.0
DPH1_k127_885801_16 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000001365 91.0
DPH1_k127_885801_17 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000002857 72.0
DPH1_k127_885801_18 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000007217 73.0
DPH1_k127_885801_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 344.0
DPH1_k127_885801_3 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 252.0
DPH1_k127_885801_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000007974 234.0
DPH1_k127_885801_5 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000000000000000000000000000000003064 218.0
DPH1_k127_885801_6 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000001901 211.0
DPH1_k127_885801_7 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000001008 205.0
DPH1_k127_885801_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000005123 180.0
DPH1_k127_885801_9 Hydrogenase expression formation protein (HypD) K04654 - - 0.00000000000000000000000000000000000000000000009106 173.0
DPH1_k127_8928006_0 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000005317 252.0
DPH1_k127_8928006_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000001048 198.0
DPH1_k127_8928006_2 - K03561,K12287 - - 0.00000000000000000000000000000000000004897 164.0
DPH1_k127_8928006_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000000007527 137.0
DPH1_k127_8928006_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000009839 48.0
DPH1_k127_9039674_0 NADH-Ubiquinone plastoquinone (complex I) K05568,K14115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 448.0
DPH1_k127_9039674_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 348.0
DPH1_k127_9039674_10 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000001341 136.0
DPH1_k127_9039674_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000000763 130.0
DPH1_k127_9039674_12 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000578 125.0
DPH1_k127_9039674_13 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000355 114.0
DPH1_k127_9039674_14 Membrane bound hydrogenase - - - 0.00000000000000000000003934 102.0
DPH1_k127_9039674_15 - - - - 0.0000000000000000000001781 101.0
DPH1_k127_9039674_16 PFAM multiple resistance and pH regulation protein F K05570 - - 0.0000000000000000000003152 99.0
DPH1_k127_9039674_17 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000002205 91.0
DPH1_k127_9039674_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000007164 87.0
DPH1_k127_9039674_19 Domain of unknown function (DUF4040) - - - 0.00000000000008637 76.0
DPH1_k127_9039674_2 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 340.0
DPH1_k127_9039674_20 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000001593 55.0
DPH1_k127_9039674_21 Ser Thr phosphatase family protein K07098 - - 0.0001537 54.0
DPH1_k127_9039674_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000002655 229.0
DPH1_k127_9039674_4 Na H ion antiporter subunit K05569 - - 0.000000000000000000000000000000000000000000000000000000000000001664 223.0
DPH1_k127_9039674_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000001998 223.0
DPH1_k127_9039674_6 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000008174 227.0
DPH1_k127_9039674_7 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000007461 203.0
DPH1_k127_9039674_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.000000000000000000000000000000000000000007575 162.0
DPH1_k127_9039674_9 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000003074 157.0
DPH1_k127_9335429_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.271e-262 819.0
DPH1_k127_9335429_1 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 407.0
DPH1_k127_9335429_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000001935 118.0
DPH1_k127_9335429_11 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000002535 131.0
DPH1_k127_9335429_13 Fibronectin type III domain - - - 0.000000000000000000000000003112 128.0
DPH1_k127_9335429_14 thiolester hydrolase activity K01259,K06889,K21193 - 3.4.11.5 0.00000000000000000000003333 112.0
DPH1_k127_9335429_15 Belongs to the peptidase S8 family - - - 0.00000000000000000000007499 112.0
DPH1_k127_9335429_16 Domain of unknown function (DUF4870) - - - 0.0000000000000000000006605 99.0
DPH1_k127_9335429_17 - K00960 - 2.7.7.6 0.00000000000000000307 85.0
DPH1_k127_9335429_18 Domain of unknown function (DUF4382) - - - 0.0000000000000004251 85.0
DPH1_k127_9335429_19 PQQ-like domain K17713 - - 0.0000000000000004662 92.0
DPH1_k127_9335429_2 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 406.0
DPH1_k127_9335429_20 PFAM Peptidase C1A, papain - - - 0.0000000000000205 86.0
DPH1_k127_9335429_21 metallopeptidase activity - - - 0.0000000000002087 83.0
DPH1_k127_9335429_22 Belongs to the peptidase S8 family K20276 - - 0.0000000000002752 84.0
DPH1_k127_9335429_23 cell wall organization - - - 0.0000000000004509 82.0
DPH1_k127_9335429_24 PFAM Nitroreductase - - - 0.0000000000005268 82.0
DPH1_k127_9335429_25 PFAM Nitroreductase - - - 0.00000000005956 76.0
DPH1_k127_9335429_26 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.000000003855 70.0
DPH1_k127_9335429_28 metallopeptidase activity - - - 0.0000001036 60.0
DPH1_k127_9335429_29 Transcriptional regulator - - - 0.0000003601 61.0
DPH1_k127_9335429_3 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 372.0
DPH1_k127_9335429_30 Rhomboid family - - - 0.000002681 60.0
DPH1_k127_9335429_31 Caspase domain - - - 0.00003284 56.0
DPH1_k127_9335429_32 EamA-like transporter family - - - 0.00004892 54.0
DPH1_k127_9335429_33 Peptidase family C25 - - - 0.00008909 56.0
DPH1_k127_9335429_34 TIGRFAM Bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.0004406 51.0
DPH1_k127_9335429_35 metallopeptidase activity - - - 0.000735 52.0
DPH1_k127_9335429_4 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 292.0
DPH1_k127_9335429_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003136 279.0
DPH1_k127_9335429_6 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004234 292.0
DPH1_k127_9335429_7 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000006119 187.0
DPH1_k127_9335429_8 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000001599 153.0
DPH1_k127_9335429_9 Cathepsin C exclusion domain K01275 GO:0000323,GO:0001775,GO:0001906,GO:0001909,GO:0001913,GO:0002250,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002449,GO:0002456,GO:0002460,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005793,GO:0005794,GO:0005798,GO:0005813,GO:0005815,GO:0005856,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006915,GO:0006955,GO:0006996,GO:0007568,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008236,GO:0009056,GO:0009057,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010952,GO:0012501,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016485,GO:0016504,GO:0016505,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0019899,GO:0019902,GO:0022607,GO:0023051,GO:0023056,GO:0030134,GO:0030135,GO:0030141,GO:0030162,GO:0030163,GO:0030234,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031404,GO:0031410,GO:0031638,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032502,GO:0032940,GO:0033116,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042176,GO:0042221,GO:0042582,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043621,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045732,GO:0045862,GO:0046903,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051087,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0051604,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0052547,GO:0060205,GO:0060255,GO:0061024,GO:0061134,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090114,GO:0097708,GO:0098588,GO:0098772,GO:0099503,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:2001233,GO:2001235 3.4.14.1 0.0000000000000000000000000000001597 141.0
DPH1_k127_9799822_0 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 418.0
DPH1_k127_9799822_1 PFAM PEGA domain - - - 0.00000000000000000000000000000000003081 152.0
DPH1_k127_9799822_2 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.00000000000005456 74.0
DPH1_k127_9799822_3 - - - - 0.000000623 55.0
DPH1_k127_9799822_4 - - - - 0.000001378 53.0