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Overview

ID MAG00735
Name DTH1_bin.34
Sample SMP0022
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family SM23-35
Genus JALHSV01
Species
Assembly information
Completeness (%) 84.48
Contamination (%) 0.0
GC content (%) 49.0
N50 (bp) 20,183
Genome size (bp) 1,391,315

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1318

Gene name Description KEGG GOs EC E-value Score Sequence
DTH1_k127_1171173_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 477.0
DTH1_k127_1171173_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 388.0
DTH1_k127_1171173_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005632 273.0
DTH1_k127_1171173_3 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000009632 175.0
DTH1_k127_1171173_4 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000542 146.0
DTH1_k127_1171173_5 PFAM Universal stress protein family - - - 0.000000000000415 80.0
DTH1_k127_1186535_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 9.999e-205 643.0
DTH1_k127_1186535_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 406.0
DTH1_k127_1186535_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 357.0
DTH1_k127_1186535_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000001305 158.0
DTH1_k127_1186535_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000002722 95.0
DTH1_k127_1186535_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000001538 89.0
DTH1_k127_118713_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 528.0
DTH1_k127_118713_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 424.0
DTH1_k127_118713_10 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000004713 88.0
DTH1_k127_118713_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 375.0
DTH1_k127_118713_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 315.0
DTH1_k127_118713_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 284.0
DTH1_k127_118713_5 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001031 273.0
DTH1_k127_118713_6 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000001199 224.0
DTH1_k127_118713_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000008316 224.0
DTH1_k127_118713_8 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000001334 154.0
DTH1_k127_118713_9 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000005583 111.0
DTH1_k127_1308455_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 1.334e-201 633.0
DTH1_k127_1308455_1 hydrogenase large subunit K14126 - 1.8.98.5 1.297e-194 618.0
DTH1_k127_1308455_10 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000003171 207.0
DTH1_k127_1308455_11 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000004995 178.0
DTH1_k127_1308455_12 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000004494 169.0
DTH1_k127_1308455_13 Domain of unknown function (DUF370) K09777 - - 0.00000000000000000000000000006643 118.0
DTH1_k127_1308455_14 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000006536 115.0
DTH1_k127_1308455_15 Sulfurtransferase TusA - - - 0.000000000000000000000001883 104.0
DTH1_k127_1308455_16 peptidyl-tyrosine sulfation - - - 0.00000000000000004674 86.0
DTH1_k127_1308455_17 Lactonase, 7-bladed beta-propeller - - - 0.00000000000009515 85.0
DTH1_k127_1308455_18 Uncharacterized ACR, COG1430 K09005 - - 0.0003912 43.0
DTH1_k127_1308455_2 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 592.0
DTH1_k127_1308455_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 551.0
DTH1_k127_1308455_4 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 528.0
DTH1_k127_1308455_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 500.0
DTH1_k127_1308455_6 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 403.0
DTH1_k127_1308455_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 377.0
DTH1_k127_1308455_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 299.0
DTH1_k127_1308455_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000002691 218.0
DTH1_k127_1309263_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.845e-280 875.0
DTH1_k127_1309263_1 Dehydratase family K01687 - 4.2.1.9 1.099e-257 807.0
DTH1_k127_1309263_10 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 454.0
DTH1_k127_1309263_11 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 445.0
DTH1_k127_1309263_12 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 429.0
DTH1_k127_1309263_13 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 351.0
DTH1_k127_1309263_14 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 323.0
DTH1_k127_1309263_15 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 304.0
DTH1_k127_1309263_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 287.0
DTH1_k127_1309263_17 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 287.0
DTH1_k127_1309263_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003778 263.0
DTH1_k127_1309263_19 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000103 264.0
DTH1_k127_1309263_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 2.1e-205 641.0
DTH1_k127_1309263_20 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008992 254.0
DTH1_k127_1309263_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000001079 245.0
DTH1_k127_1309263_22 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002431 244.0
DTH1_k127_1309263_23 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003587 242.0
DTH1_k127_1309263_24 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000008768 241.0
DTH1_k127_1309263_25 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000002228 225.0
DTH1_k127_1309263_26 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000000000000005121 173.0
DTH1_k127_1309263_27 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000002263 168.0
DTH1_k127_1309263_28 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000000000000005587 151.0
DTH1_k127_1309263_29 radical SAM domain protein - - - 0.0000000000000000000000000000000000105 151.0
DTH1_k127_1309263_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 3.123e-201 631.0
DTH1_k127_1309263_30 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000002163 154.0
DTH1_k127_1309263_31 PFAM Smr protein MutS2 - - - 0.000000000000000000000000000000001721 132.0
DTH1_k127_1309263_32 PFAM Smr protein MutS2 - - - 0.000000000000000000000000000003011 127.0
DTH1_k127_1309263_33 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000007136 123.0
DTH1_k127_1309263_34 Transposase K07491 - - 0.0000000000000000000000000004053 118.0
DTH1_k127_1309263_35 Protein of unknown function (DUF465) K09794 - - 0.000000000000000009525 85.0
DTH1_k127_1309263_36 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.00000000000000002059 92.0
DTH1_k127_1309263_37 integral membrane protein - - - 0.00000000008814 69.0
DTH1_k127_1309263_38 Glutaredoxin K03676 - - 0.0000000002588 62.0
DTH1_k127_1309263_4 Fructose-bisphosphate aldolase class-II - - - 6.599e-197 622.0
DTH1_k127_1309263_5 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 572.0
DTH1_k127_1309263_6 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 560.0
DTH1_k127_1309263_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 485.0
DTH1_k127_1309263_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 488.0
DTH1_k127_1309263_9 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 459.0
DTH1_k127_1317353_0 coenzyme F390 synthetase K01912 - 6.2.1.30 3.53e-210 661.0
DTH1_k127_1317353_1 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 1.366e-204 651.0
DTH1_k127_1317353_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 304.0
DTH1_k127_1317353_11 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 293.0
DTH1_k127_1317353_12 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001209 276.0
DTH1_k127_1317353_13 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004234 263.0
DTH1_k127_1317353_14 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000005408 239.0
DTH1_k127_1317353_15 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000001064 225.0
DTH1_k127_1317353_16 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000001269 217.0
DTH1_k127_1317353_17 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000001654 203.0
DTH1_k127_1317353_18 amino acid-binding ACT - - - 0.000000000000000000000000000000000000000000000000000000004465 201.0
DTH1_k127_1317353_19 - - - - 0.000000000000000000000000000000000000000001247 160.0
DTH1_k127_1317353_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 1.916e-202 637.0
DTH1_k127_1317353_20 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000001574 158.0
DTH1_k127_1317353_21 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000001359 121.0
DTH1_k127_1317353_22 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000002356 116.0
DTH1_k127_1317353_23 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000242 109.0
DTH1_k127_1317353_24 part of a sulfur-relay system - - - 0.000000000000000000000062 98.0
DTH1_k127_1317353_26 Recombinase - - - 0.00003433 48.0
DTH1_k127_1317353_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.286e-199 630.0
DTH1_k127_1317353_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 582.0
DTH1_k127_1317353_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 406.0
DTH1_k127_1317353_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 360.0
DTH1_k127_1317353_7 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 333.0
DTH1_k127_1317353_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 318.0
DTH1_k127_1317353_9 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 316.0
DTH1_k127_1320226_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.425e-199 629.0
DTH1_k127_1320226_1 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 593.0
DTH1_k127_1320226_10 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001898 278.0
DTH1_k127_1320226_11 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004778 278.0
DTH1_k127_1320226_12 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
DTH1_k127_1320226_13 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002334 272.0
DTH1_k127_1320226_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
DTH1_k127_1320226_15 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000004157 242.0
DTH1_k127_1320226_16 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000007478 237.0
DTH1_k127_1320226_17 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000008305 212.0
DTH1_k127_1320226_18 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000001493 207.0
DTH1_k127_1320226_19 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000003517 174.0
DTH1_k127_1320226_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 560.0
DTH1_k127_1320226_20 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000005212 162.0
DTH1_k127_1320226_21 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000001242 152.0
DTH1_k127_1320226_22 methyltransferase - - - 0.0000000000000000000000000000000000004067 147.0
DTH1_k127_1320226_23 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000005802 143.0
DTH1_k127_1320226_24 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.00000000000000000000000000002665 119.0
DTH1_k127_1320226_25 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000003489 118.0
DTH1_k127_1320226_27 - - - - 0.0000000000000000000001941 102.0
DTH1_k127_1320226_29 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000001677 87.0
DTH1_k127_1320226_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 552.0
DTH1_k127_1320226_30 Evidence 5 No homology to any previously reported sequences K03765 - - 0.000000000000002104 90.0
DTH1_k127_1320226_31 - - - - 0.0000003963 57.0
DTH1_k127_1320226_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 451.0
DTH1_k127_1320226_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 414.0
DTH1_k127_1320226_6 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 371.0
DTH1_k127_1320226_7 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 326.0
DTH1_k127_1320226_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 309.0
DTH1_k127_1320226_9 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 311.0
DTH1_k127_1327019_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 602.0
DTH1_k127_1327019_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 451.0
DTH1_k127_1327019_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 392.0
DTH1_k127_1327019_3 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 341.0
DTH1_k127_1327019_4 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000003376 238.0
DTH1_k127_1327019_5 nuclease activity K06218 - - 0.00000000000000000000000002129 110.0
DTH1_k127_1327019_6 AsmA-like C-terminal region - - - 0.00000000000000000003646 93.0
DTH1_k127_1327019_7 - - - - 0.000000000000000005008 85.0
DTH1_k127_1327019_9 Virulence protein RhuM family - - - 0.0000001749 55.0
DTH1_k127_1422657_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1183.0
DTH1_k127_1422657_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 441.0
DTH1_k127_1422657_2 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 428.0
DTH1_k127_1422657_3 PFAM pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000007331 151.0
DTH1_k127_1422657_4 Protein of unknown function (DUF2878) - - - 0.00000000000000000000000000000000003245 143.0
DTH1_k127_1422657_5 COGs COG4446 conserved - - - 0.00000000000000000000000000000331 125.0
DTH1_k127_1422657_6 nucleoside-diphosphate sugar epimerase K07071 - - 0.00001153 49.0
DTH1_k127_1429693_0 Glycosyltransferase like family 2 K07011,K20444 - - 1.845e-274 874.0
DTH1_k127_1429693_1 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 431.0
DTH1_k127_1455257_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1020.0
DTH1_k127_1455257_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.982e-248 775.0
DTH1_k127_1455257_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 495.0
DTH1_k127_1455257_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 425.0
DTH1_k127_1455257_4 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 378.0
DTH1_k127_1455257_5 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007817 257.0
DTH1_k127_1455257_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000001705 249.0
DTH1_k127_1455257_7 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000003032 234.0
DTH1_k127_1455257_8 belongs to the Fur family K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.000000000000000000000000000000000000000000001005 171.0
DTH1_k127_1527649_0 Surface antigen K07277 - - 1.233e-258 819.0
DTH1_k127_1527649_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 3.724e-204 646.0
DTH1_k127_1527649_10 lyase activity - - - 0.0000000000000000000000002507 110.0
DTH1_k127_1527649_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 447.0
DTH1_k127_1527649_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 394.0
DTH1_k127_1527649_4 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 386.0
DTH1_k127_1527649_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 379.0
DTH1_k127_1527649_6 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003969 258.0
DTH1_k127_1527649_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000317 176.0
DTH1_k127_1527649_8 Lysin motif - - - 0.0000000000000000000000000000007588 134.0
DTH1_k127_1527649_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000008974 125.0
DTH1_k127_1538220_0 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002469 273.0
DTH1_k127_1538220_1 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000001022 203.0
DTH1_k127_1538220_2 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000001279 178.0
DTH1_k127_1538220_3 - - - - 0.000000000000000000000006236 111.0
DTH1_k127_1573714_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1752.0
DTH1_k127_1573714_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.573e-312 963.0
DTH1_k127_1573714_10 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 353.0
DTH1_k127_1573714_11 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 342.0
DTH1_k127_1573714_12 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 346.0
DTH1_k127_1573714_13 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 324.0
DTH1_k127_1573714_14 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 302.0
DTH1_k127_1573714_15 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 297.0
DTH1_k127_1573714_16 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
DTH1_k127_1573714_17 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000006574 231.0
DTH1_k127_1573714_18 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000003311 227.0
DTH1_k127_1573714_19 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000004862 220.0
DTH1_k127_1573714_2 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 1.488e-250 785.0
DTH1_k127_1573714_20 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000694 190.0
DTH1_k127_1573714_21 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000001292 170.0
DTH1_k127_1573714_22 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000004582 162.0
DTH1_k127_1573714_23 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.000000000000000000000000000000000000000002819 159.0
DTH1_k127_1573714_24 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000103 151.0
DTH1_k127_1573714_25 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000007733 129.0
DTH1_k127_1573714_26 SMART Cold shock protein K03704 - - 0.0000000000000000000000000001136 116.0
DTH1_k127_1573714_28 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000001751 109.0
DTH1_k127_1573714_29 iron-sulfur cluster assembly - - - 0.00000000000000000000004769 100.0
DTH1_k127_1573714_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.591e-225 710.0
DTH1_k127_1573714_30 cobalt transport protein K16785 - - 0.00000007511 62.0
DTH1_k127_1573714_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.155e-220 694.0
DTH1_k127_1573714_5 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 537.0
DTH1_k127_1573714_6 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 486.0
DTH1_k127_1573714_7 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 487.0
DTH1_k127_1573714_8 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 377.0
DTH1_k127_1573714_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 376.0
DTH1_k127_1640378_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.616e-274 853.0
DTH1_k127_1640378_1 Endoribonuclease that initiates mRNA decay K18682 - - 6.756e-207 656.0
DTH1_k127_1640378_10 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 332.0
DTH1_k127_1640378_11 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 315.0
DTH1_k127_1640378_12 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 314.0
DTH1_k127_1640378_13 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 303.0
DTH1_k127_1640378_14 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 286.0
DTH1_k127_1640378_15 Protein of unknown function DUF89 K09116,K09680 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 278.0
DTH1_k127_1640378_16 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000006092 257.0
DTH1_k127_1640378_17 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000002244 231.0
DTH1_k127_1640378_18 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000205 208.0
DTH1_k127_1640378_19 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000000002586 204.0
DTH1_k127_1640378_2 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 616.0
DTH1_k127_1640378_20 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000001432 195.0
DTH1_k127_1640378_21 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000716 183.0
DTH1_k127_1640378_22 belongs to the Fur family K02076,K03711,K09823 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000001102 182.0
DTH1_k127_1640378_23 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000633 183.0
DTH1_k127_1640378_24 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000000000001979 161.0
DTH1_k127_1640378_25 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000006387 159.0
DTH1_k127_1640378_26 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000001706 164.0
DTH1_k127_1640378_27 Transcriptional regulator - - - 0.000000000000000000000000000000000000001634 155.0
DTH1_k127_1640378_28 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000001104 130.0
DTH1_k127_1640378_29 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000001469 96.0
DTH1_k127_1640378_3 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 518.0
DTH1_k127_1640378_30 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000002046 87.0
DTH1_k127_1640378_31 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000009505 83.0
DTH1_k127_1640378_32 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000002309 71.0
DTH1_k127_1640378_33 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000005274 58.0
DTH1_k127_1640378_34 PFAM Beta propeller domain K14475 - - 0.0008371 48.0
DTH1_k127_1640378_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 460.0
DTH1_k127_1640378_5 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 421.0
DTH1_k127_1640378_6 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 404.0
DTH1_k127_1640378_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 379.0
DTH1_k127_1640378_8 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 358.0
DTH1_k127_1640378_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 343.0
DTH1_k127_1648638_0 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 566.0
DTH1_k127_1648638_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 555.0
DTH1_k127_1648638_2 PFAM Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 443.0
DTH1_k127_1648638_3 UDP-N-acetylglucosamine 2-epimerase activity K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000001958 239.0
DTH1_k127_1648638_4 Polymer-forming cytoskeletal K12287 - - 0.0000000000000000000000000000000000001321 155.0
DTH1_k127_1648638_5 - - - - 0.0000000000000000000001763 107.0
DTH1_k127_1648638_6 flavin reductase - - - 0.0000000000000003431 79.0
DTH1_k127_165923_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 599.0
DTH1_k127_165923_1 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 544.0
DTH1_k127_165923_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 361.0
DTH1_k127_165923_11 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 352.0
DTH1_k127_165923_12 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 349.0
DTH1_k127_165923_13 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 304.0
DTH1_k127_165923_14 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000004857 258.0
DTH1_k127_165923_15 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000004429 227.0
DTH1_k127_165923_16 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000001315 160.0
DTH1_k127_165923_17 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000119 135.0
DTH1_k127_165923_18 Essential cell division protein K03589 - - 0.0000000000000000008332 96.0
DTH1_k127_165923_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 519.0
DTH1_k127_165923_20 Stringent starvation protein B K09985 - - 0.0000006137 57.0
DTH1_k127_165923_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 476.0
DTH1_k127_165923_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 426.0
DTH1_k127_165923_5 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
DTH1_k127_165923_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 408.0
DTH1_k127_165923_7 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 388.0
DTH1_k127_165923_8 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 387.0
DTH1_k127_165923_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 381.0
DTH1_k127_1687883_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 529.0
DTH1_k127_1687883_1 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 462.0
DTH1_k127_1687883_10 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.0000000000000000000000000000000000000000000000000000005617 223.0
DTH1_k127_1687883_11 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000000000000000000000001373 205.0
DTH1_k127_1687883_12 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000001391 169.0
DTH1_k127_1687883_13 - - - - 0.0000000000000000000000000000000000008692 145.0
DTH1_k127_1687883_14 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.00000000000000000000005661 99.0
DTH1_k127_1687883_15 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000002194 59.0
DTH1_k127_1687883_2 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 446.0
DTH1_k127_1687883_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 416.0
DTH1_k127_1687883_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 390.0
DTH1_k127_1687883_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 366.0
DTH1_k127_1687883_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 378.0
DTH1_k127_1687883_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 301.0
DTH1_k127_1687883_8 PFAM secretion protein HlyD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 301.0
DTH1_k127_1687883_9 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
DTH1_k127_1985065_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1581.0
DTH1_k127_1985065_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.825e-313 983.0
DTH1_k127_1985065_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.129e-198 624.0
DTH1_k127_1985065_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 504.0
DTH1_k127_1985065_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 494.0
DTH1_k127_1985065_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 407.0
DTH1_k127_1985065_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001548 243.0
DTH1_k127_1985065_7 Translation initiation factor SUI1 K03113 - - 0.000000000000000004754 88.0
DTH1_k127_1985065_8 - - - - 0.000000000000000764 81.0
DTH1_k127_1985065_9 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000007952 49.0
DTH1_k127_2300224_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 413.0
DTH1_k127_2300224_1 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 389.0
DTH1_k127_2300224_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 361.0
DTH1_k127_2300224_3 Protein of unknown function (DUF3124) - - - 0.00000002535 55.0
DTH1_k127_2307633_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1068.0
DTH1_k127_2307633_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 323.0
DTH1_k127_2307633_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
DTH1_k127_2307633_3 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000005712 266.0
DTH1_k127_2307633_4 Domain of unknown function (DUF4412) - - - 0.00000000000000000000005368 106.0
DTH1_k127_2307633_5 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000005797 60.0
DTH1_k127_2731233_0 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 518.0
DTH1_k127_2731233_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 366.0
DTH1_k127_2731233_2 NADPH-dependent FMN reductase K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 331.0
DTH1_k127_2731233_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 317.0
DTH1_k127_2731233_4 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000003085 210.0
DTH1_k127_2731233_5 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000005728 121.0
DTH1_k127_2731233_6 RelB antitoxin K07473 - - 0.000000000000000000000000005329 112.0
DTH1_k127_2731233_7 TIGRFAM addiction module toxin component, YafQ family K19157 - - 0.0000000000000000000000001814 108.0
DTH1_k127_2731233_8 Lipid A biosynthesis K02517 - 2.3.1.241 0.000001975 59.0
DTH1_k127_2731233_9 HMGL-like - - - 0.0000351 54.0
DTH1_k127_2873218_0 Sulphur transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 414.0
DTH1_k127_2873218_2 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000005121 203.0
DTH1_k127_2873218_3 Protein of unknown function (DUF3592) - - - 0.0000000000001292 82.0
DTH1_k127_2873218_4 - - - - 0.0000004287 56.0
DTH1_k127_3003693_0 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 530.0
DTH1_k127_3003693_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 400.0
DTH1_k127_3003693_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 348.0
DTH1_k127_3003693_3 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 327.0
DTH1_k127_3003693_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000001061 174.0
DTH1_k127_3003693_5 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000001364 139.0
DTH1_k127_3003693_6 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0000000000000000000000000000000002475 133.0
DTH1_k127_3003693_7 - - - - 0.00001349 47.0
DTH1_k127_3054189_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 506.0
DTH1_k127_3054189_1 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 434.0
DTH1_k127_3054189_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000001169 204.0
DTH1_k127_3054189_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000003305 186.0
DTH1_k127_3054189_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000008793 157.0
DTH1_k127_3054189_13 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000002502 163.0
DTH1_k127_3054189_14 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000000007746 132.0
DTH1_k127_3054189_15 Ribosomal protein S16 K02959 - - 0.000000000000000000000000002168 112.0
DTH1_k127_3054189_2 PFAM Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 381.0
DTH1_k127_3054189_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 372.0
DTH1_k127_3054189_4 wide pore channel activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 361.0
DTH1_k127_3054189_5 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 316.0
DTH1_k127_3054189_6 CHASE2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 334.0
DTH1_k127_3054189_7 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
DTH1_k127_3054189_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008728 270.0
DTH1_k127_3054189_9 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000108 254.0
DTH1_k127_323987_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1255.0
DTH1_k127_323987_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1045.0
DTH1_k127_323987_10 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 481.0
DTH1_k127_323987_11 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 434.0
DTH1_k127_323987_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 391.0
DTH1_k127_323987_13 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 385.0
DTH1_k127_323987_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 366.0
DTH1_k127_323987_15 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 361.0
DTH1_k127_323987_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 367.0
DTH1_k127_323987_17 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 345.0
DTH1_k127_323987_18 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 336.0
DTH1_k127_323987_19 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 323.0
DTH1_k127_323987_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.161e-287 901.0
DTH1_k127_323987_20 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 322.0
DTH1_k127_323987_21 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 315.0
DTH1_k127_323987_22 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 314.0
DTH1_k127_323987_23 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 285.0
DTH1_k127_323987_24 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001008 283.0
DTH1_k127_323987_25 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002169 284.0
DTH1_k127_323987_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 272.0
DTH1_k127_323987_27 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005016 267.0
DTH1_k127_323987_28 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000001073 254.0
DTH1_k127_323987_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008908 252.0
DTH1_k127_323987_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.905e-220 688.0
DTH1_k127_323987_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006206 238.0
DTH1_k127_323987_31 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000006772 234.0
DTH1_k127_323987_32 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000004033 231.0
DTH1_k127_323987_33 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000003869 226.0
DTH1_k127_323987_34 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000004576 235.0
DTH1_k127_323987_35 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000006657 228.0
DTH1_k127_323987_36 HDIG domain protein K06950 - - 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
DTH1_k127_323987_37 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000003644 212.0
DTH1_k127_323987_38 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003788 215.0
DTH1_k127_323987_39 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000006795 211.0
DTH1_k127_323987_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 592.0
DTH1_k127_323987_40 Acyltransferase family K16568 - - 0.00000000000000000000000000000000000000000000000000000000003128 219.0
DTH1_k127_323987_41 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008076 205.0
DTH1_k127_323987_42 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000006769 183.0
DTH1_k127_323987_43 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000007977 201.0
DTH1_k127_323987_44 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000001764 177.0
DTH1_k127_323987_45 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001598 169.0
DTH1_k127_323987_46 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000001214 168.0
DTH1_k127_323987_47 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000008111 166.0
DTH1_k127_323987_48 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000004365 166.0
DTH1_k127_323987_49 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000197 156.0
DTH1_k127_323987_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 563.0
DTH1_k127_323987_50 HNH nucleases - - - 0.00000000000000000000000000000000000000002476 156.0
DTH1_k127_323987_51 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000001653 153.0
DTH1_k127_323987_52 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000006874 153.0
DTH1_k127_323987_53 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000105 145.0
DTH1_k127_323987_54 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000002362 140.0
DTH1_k127_323987_55 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000009544 127.0
DTH1_k127_323987_56 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000007642 124.0
DTH1_k127_323987_57 PFAM Glutaredoxin K06191 - - 0.00000000000000000000000000002005 119.0
DTH1_k127_323987_58 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000004197 117.0
DTH1_k127_323987_59 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000000000000006971 130.0
DTH1_k127_323987_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 562.0
DTH1_k127_323987_60 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000001383 110.0
DTH1_k127_323987_61 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.00000000000000000000000001395 109.0
DTH1_k127_323987_62 Na -dependent transporter K03453 - - 0.00000000000000000000000006306 119.0
DTH1_k127_323987_63 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001764 106.0
DTH1_k127_323987_64 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000001772 111.0
DTH1_k127_323987_65 NIL - - - 0.0000000000000000000000009379 105.0
DTH1_k127_323987_66 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001886 106.0
DTH1_k127_323987_67 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000001522 86.0
DTH1_k127_323987_68 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001423 75.0
DTH1_k127_323987_69 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002992 72.0
DTH1_k127_323987_7 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 557.0
DTH1_k127_323987_70 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000008623 76.0
DTH1_k127_323987_71 Putative regulatory protein - - - 0.000001483 52.0
DTH1_k127_323987_8 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 516.0
DTH1_k127_323987_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 500.0
DTH1_k127_3240226_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.07e-260 822.0
DTH1_k127_3240226_1 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000001319 149.0
DTH1_k127_3617389_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.593e-284 884.0
DTH1_k127_3617389_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.201e-250 794.0
DTH1_k127_3617389_10 Ami_3 - - - 0.00000000001313 76.0
DTH1_k127_3617389_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 563.0
DTH1_k127_3617389_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 358.0
DTH1_k127_3617389_4 UV-endonuclease UvdE K13281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 348.0
DTH1_k127_3617389_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 331.0
DTH1_k127_3617389_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 318.0
DTH1_k127_3617389_7 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000003515 156.0
DTH1_k127_3617389_8 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000000000000000000000000000000005919 153.0
DTH1_k127_3617389_9 Sporulation and spore germination - - - 0.0000000000000001633 87.0
DTH1_k127_3743337_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.949e-267 841.0
DTH1_k127_3743337_1 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 514.0
DTH1_k127_3743337_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 390.0
DTH1_k127_3743337_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000008576 194.0
DTH1_k127_3860315_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 493.0
DTH1_k127_3860315_1 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 301.0
DTH1_k127_3860315_2 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005145 232.0
DTH1_k127_3860315_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000699 142.0
DTH1_k127_3860315_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000008243 139.0
DTH1_k127_3860315_5 OstA-like protein K09774 - - 0.00000000000000000000000000000001775 132.0
DTH1_k127_3860315_6 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.0003393 50.0
DTH1_k127_3888215_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1146.0
DTH1_k127_3888215_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.881e-240 754.0
DTH1_k127_3888215_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000003775 177.0
DTH1_k127_3888215_11 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000234 110.0
DTH1_k127_3888215_12 phosphorelay signal transduction system - - - 0.000000000000000000003963 102.0
DTH1_k127_3888215_13 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000001443 63.0
DTH1_k127_3888215_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 504.0
DTH1_k127_3888215_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 440.0
DTH1_k127_3888215_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 368.0
DTH1_k127_3888215_5 metal-dependent enzyme K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 317.0
DTH1_k127_3888215_6 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 309.0
DTH1_k127_3888215_7 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004536 265.0
DTH1_k127_3888215_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
DTH1_k127_3888215_9 Dihydroorotate dehydrogenase electron transfer subunit K02823 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114 - 0.000000000000000000000000000000000000000000000000653 184.0
DTH1_k127_3933549_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1209.0
DTH1_k127_3933549_1 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 576.0
DTH1_k127_3933549_10 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000004698 168.0
DTH1_k127_3933549_11 Bacterial regulatory protein, Fis family K02481 - - 0.00000000000000000000000000000000004074 142.0
DTH1_k127_3933549_12 cell redox homeostasis - - - 0.000000000000000000000000005889 111.0
DTH1_k127_3933549_13 EamA-like transporter family - - - 0.00000002137 56.0
DTH1_k127_3933549_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 456.0
DTH1_k127_3933549_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 318.0
DTH1_k127_3933549_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
DTH1_k127_3933549_5 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
DTH1_k127_3933549_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 297.0
DTH1_k127_3933549_7 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 278.0
DTH1_k127_3933549_8 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
DTH1_k127_3933549_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000004164 258.0
DTH1_k127_3975142_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 450.0
DTH1_k127_3975142_1 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 434.0
DTH1_k127_3975142_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001265 216.0
DTH1_k127_3975142_11 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.000000000000000000000000000000000000000000000000000000000128 209.0
DTH1_k127_3975142_12 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000002546 195.0
DTH1_k127_3975142_13 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000001372 202.0
DTH1_k127_3975142_14 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000000000000000003249 146.0
DTH1_k127_3975142_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000142 123.0
DTH1_k127_3975142_16 - - - - 0.000000000000000000002944 97.0
DTH1_k127_3975142_17 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000001009 98.0
DTH1_k127_3975142_18 Protein of unknown function (DUF2905) - - - 0.000000000000000000255 90.0
DTH1_k127_3975142_19 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000001357 88.0
DTH1_k127_3975142_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 399.0
DTH1_k127_3975142_20 3D domain protein - - - 0.000000002622 63.0
DTH1_k127_3975142_21 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0008529 50.0
DTH1_k127_3975142_3 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 374.0
DTH1_k127_3975142_4 Major Facilitator Superfamily K16210 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 363.0
DTH1_k127_3975142_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 340.0
DTH1_k127_3975142_6 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 287.0
DTH1_k127_3975142_7 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009902 287.0
DTH1_k127_3975142_8 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001212 274.0
DTH1_k127_3975142_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000003613 263.0
DTH1_k127_4102397_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 517.0
DTH1_k127_4102397_1 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 509.0
DTH1_k127_4102397_2 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 495.0
DTH1_k127_4102397_3 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 505.0
DTH1_k127_4102397_4 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 341.0
DTH1_k127_4102397_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 292.0
DTH1_k127_4102397_6 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001528 274.0
DTH1_k127_4102397_7 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000001093 176.0
DTH1_k127_4102397_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000008448 123.0
DTH1_k127_4102397_9 cytochrome C peroxidase - - - 0.00000000000002628 76.0
DTH1_k127_4208596_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 6.122e-253 795.0
DTH1_k127_4208596_1 glycolate transport K14393 - - 8.614e-222 699.0
DTH1_k127_4208596_2 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 515.0
DTH1_k127_4208596_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 400.0
DTH1_k127_4208596_4 branched-chain-amino-acid transaminase activity K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004092 279.0
DTH1_k127_4208596_5 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004636 250.0
DTH1_k127_4208596_6 Lipoate--protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000001104 169.0
DTH1_k127_4208596_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000001219 159.0
DTH1_k127_4208596_8 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000001944 149.0
DTH1_k127_4208596_9 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000004458 116.0
DTH1_k127_4400099_0 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000001778 159.0
DTH1_k127_4400099_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000509 95.0
DTH1_k127_4400099_2 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.0000000001614 72.0
DTH1_k127_4400099_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00002578 47.0
DTH1_k127_4451658_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 8.689e-261 816.0
DTH1_k127_4451658_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 8.658e-229 722.0
DTH1_k127_4451658_10 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 340.0
DTH1_k127_4451658_11 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 323.0
DTH1_k127_4451658_12 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 317.0
DTH1_k127_4451658_13 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003145 259.0
DTH1_k127_4451658_14 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000004921 258.0
DTH1_k127_4451658_15 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
DTH1_k127_4451658_16 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000004196 233.0
DTH1_k127_4451658_17 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000002094 177.0
DTH1_k127_4451658_18 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000002402 169.0
DTH1_k127_4451658_19 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000000000000692 152.0
DTH1_k127_4451658_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.091e-209 659.0
DTH1_k127_4451658_20 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000002345 108.0
DTH1_k127_4451658_21 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001449 106.0
DTH1_k127_4451658_22 - - - - 0.000000000000000000000007471 105.0
DTH1_k127_4451658_23 Type II secretion system protein B K02451 - - 0.0000000000000000000003555 106.0
DTH1_k127_4451658_24 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000002332 61.0
DTH1_k127_4451658_25 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00003487 47.0
DTH1_k127_4451658_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 567.0
DTH1_k127_4451658_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 541.0
DTH1_k127_4451658_5 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 509.0
DTH1_k127_4451658_6 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 501.0
DTH1_k127_4451658_7 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 479.0
DTH1_k127_4451658_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 459.0
DTH1_k127_4451658_9 PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 347.0
DTH1_k127_476588_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1135.0
DTH1_k127_476588_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 7.538e-253 802.0
DTH1_k127_476588_10 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 371.0
DTH1_k127_476588_11 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 326.0
DTH1_k127_476588_12 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002434 268.0
DTH1_k127_476588_13 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000009401 222.0
DTH1_k127_476588_14 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000002744 219.0
DTH1_k127_476588_15 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000005014 221.0
DTH1_k127_476588_16 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000194 211.0
DTH1_k127_476588_17 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000002289 117.0
DTH1_k127_476588_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000003974 106.0
DTH1_k127_476588_19 Tetratricopeptide repeat - - - 0.0005146 47.0
DTH1_k127_476588_2 GTP-binding GTPase Middle Region K03665 - - 1.082e-200 638.0
DTH1_k127_476588_3 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 591.0
DTH1_k127_476588_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 563.0
DTH1_k127_476588_5 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 499.0
DTH1_k127_476588_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 433.0
DTH1_k127_476588_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 431.0
DTH1_k127_476588_8 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 402.0
DTH1_k127_476588_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 392.0
DTH1_k127_4777507_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.927e-251 792.0
DTH1_k127_4777507_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 6.406e-244 760.0
DTH1_k127_4777507_10 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000009584 54.0
DTH1_k127_4777507_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.045e-222 704.0
DTH1_k127_4777507_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000005653 192.0
DTH1_k127_4777507_4 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000002887 189.0
DTH1_k127_4777507_5 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000000001213 184.0
DTH1_k127_4777507_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000007477 187.0
DTH1_k127_4777507_7 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000009643 148.0
DTH1_k127_4777507_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002684 116.0
DTH1_k127_4777507_9 Nitroreductase family - - - 0.000000000000000000001383 95.0
DTH1_k127_4807619_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 7.5e-220 692.0
DTH1_k127_4807619_1 Aminotransferase class-III K01845 - 5.4.3.8 2.694e-200 631.0
DTH1_k127_4807619_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 402.0
DTH1_k127_4807619_11 UDP-glucose (Heptosyl) LPS alpha 1,3-glucosyltransferase WaaG K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 396.0
DTH1_k127_4807619_12 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 379.0
DTH1_k127_4807619_13 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 349.0
DTH1_k127_4807619_14 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 342.0
DTH1_k127_4807619_15 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 289.0
DTH1_k127_4807619_16 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 293.0
DTH1_k127_4807619_17 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001422 259.0
DTH1_k127_4807619_19 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000005015 220.0
DTH1_k127_4807619_2 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 574.0
DTH1_k127_4807619_20 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005407 218.0
DTH1_k127_4807619_21 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000001777 210.0
DTH1_k127_4807619_22 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000003893 194.0
DTH1_k127_4807619_23 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.00000000000000000000000000000000000000000000000002864 183.0
DTH1_k127_4807619_24 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000001402 183.0
DTH1_k127_4807619_25 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000001201 182.0
DTH1_k127_4807619_26 competence protein - - - 0.00000000000000000000000000000000000000127 156.0
DTH1_k127_4807619_27 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000003207 136.0
DTH1_k127_4807619_28 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000000000004074 142.0
DTH1_k127_4807619_29 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000009659 138.0
DTH1_k127_4807619_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 552.0
DTH1_k127_4807619_30 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000001199 96.0
DTH1_k127_4807619_31 - - - - 0.0000000000000000185 90.0
DTH1_k127_4807619_32 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000001559 86.0
DTH1_k127_4807619_33 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000001889 71.0
DTH1_k127_4807619_34 Tetratricopeptide repeat-like domain - - - 0.00000000003629 72.0
DTH1_k127_4807619_35 One HIP oligomer binds the ATPase domains of at least two Hsc70 molecules dependent on activation of the Hsc70 ATPase by Hsp40. Stabilizes the ADP state of Hsc70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of Hsc70 with various target proteins (By similarity) K09560 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030544,GO:0030554,GO:0030674,GO:0031072,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060090,GO:0061077,GO:0061083,GO:0061084,GO:0065003,GO:0065007,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1903332,GO:1903333 - 0.00000000178 66.0
DTH1_k127_4807619_36 Lipid A core - O-antigen ligase K18814 - - 0.00000003559 65.0
DTH1_k127_4807619_37 PilZ domain - - - 0.00006468 51.0
DTH1_k127_4807619_38 hmm pf04305 - - - 0.0004335 47.0
DTH1_k127_4807619_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 531.0
DTH1_k127_4807619_5 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 512.0
DTH1_k127_4807619_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 508.0
DTH1_k127_4807619_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 490.0
DTH1_k127_4807619_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 461.0
DTH1_k127_4807619_9 cysteine synthase A K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 442.0
DTH1_k127_5021369_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1501.0
DTH1_k127_5021369_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.16e-262 815.0
DTH1_k127_5021369_10 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000009152 199.0
DTH1_k127_5021369_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000953 206.0
DTH1_k127_5021369_12 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000001979 197.0
DTH1_k127_5021369_13 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000001003 202.0
DTH1_k127_5021369_14 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000004503 179.0
DTH1_k127_5021369_15 methyltransferase activity - - - 0.0000000000000000000000000000000000000000002439 164.0
DTH1_k127_5021369_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.909e-203 646.0
DTH1_k127_5021369_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 590.0
DTH1_k127_5021369_4 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 481.0
DTH1_k127_5021369_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 461.0
DTH1_k127_5021369_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 316.0
DTH1_k127_5021369_7 pfam psp1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008537 249.0
DTH1_k127_5021369_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002089 241.0
DTH1_k127_5021369_9 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000001918 214.0
DTH1_k127_5054029_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1020.0
DTH1_k127_5054029_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 4.622e-241 764.0
DTH1_k127_5054029_2 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 4.712e-214 689.0
DTH1_k127_5054029_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 467.0
DTH1_k127_5054029_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000005261 213.0
DTH1_k127_5054029_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000000000000000000000000026 198.0
DTH1_k127_5054029_6 Universal stress protein - - - 0.000000000000000000000000000000000000000388 153.0
DTH1_k127_5054029_7 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000009999 151.0
DTH1_k127_5054029_8 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000274 68.0
DTH1_k127_5161885_0 FeoA K04759 - - 8.853e-260 820.0
DTH1_k127_5161885_1 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 306.0
DTH1_k127_5161885_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000003201 133.0
DTH1_k127_5161885_3 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000234 106.0
DTH1_k127_5161885_4 FeoA K04759 - - 0.00000000000001411 78.0
DTH1_k127_5186357_0 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 390.0
DTH1_k127_5186357_1 Ion channel K10716 - - 0.0000000000000000004888 91.0
DTH1_k127_5186357_2 - - - - 0.000002515 51.0
DTH1_k127_5207081_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.176e-314 979.0
DTH1_k127_5207081_1 Protein of unknown function, DUF255 K06888 - - 6.304e-248 781.0
DTH1_k127_5207081_10 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
DTH1_k127_5207081_11 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 471.0
DTH1_k127_5207081_12 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 447.0
DTH1_k127_5207081_13 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 435.0
DTH1_k127_5207081_14 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 415.0
DTH1_k127_5207081_15 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 390.0
DTH1_k127_5207081_16 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 352.0
DTH1_k127_5207081_17 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 351.0
DTH1_k127_5207081_18 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 340.0
DTH1_k127_5207081_19 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 316.0
DTH1_k127_5207081_2 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 7.681e-218 685.0
DTH1_k127_5207081_20 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 301.0
DTH1_k127_5207081_21 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
DTH1_k127_5207081_22 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 297.0
DTH1_k127_5207081_23 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 296.0
DTH1_k127_5207081_24 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001798 282.0
DTH1_k127_5207081_25 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003142 285.0
DTH1_k127_5207081_26 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000004508 259.0
DTH1_k127_5207081_27 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
DTH1_k127_5207081_28 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000348 202.0
DTH1_k127_5207081_29 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000007731 194.0
DTH1_k127_5207081_3 cell redox homeostasis - - - 1.319e-217 684.0
DTH1_k127_5207081_30 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000002256 190.0
DTH1_k127_5207081_31 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000001574 147.0
DTH1_k127_5207081_32 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000002968 101.0
DTH1_k127_5207081_34 Putative zinc- or iron-chelating domain - - - 0.0000000000000008213 82.0
DTH1_k127_5207081_35 DUF167 - - - 0.00000000000001401 76.0
DTH1_k127_5207081_36 peptidyl-tyrosine sulfation - - - 0.00000000003592 73.0
DTH1_k127_5207081_37 - - - - 0.000001531 56.0
DTH1_k127_5207081_38 Helix-turn-helix domain - - - 0.0002984 50.0
DTH1_k127_5207081_4 PFAM magnesium chelatase ChlI subunit K07391 - - 1.21e-205 651.0
DTH1_k127_5207081_5 Metallo-beta-lactamase superfamily - - - 7.577e-195 621.0
DTH1_k127_5207081_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 608.0
DTH1_k127_5207081_7 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 592.0
DTH1_k127_5207081_8 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 484.0
DTH1_k127_5207081_9 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 466.0
DTH1_k127_5269679_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 563.0
DTH1_k127_5269679_1 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 396.0
DTH1_k127_5269679_10 PFAM pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000001255 155.0
DTH1_k127_5269679_11 - - - - 0.0000000000000000000000000000000000000741 147.0
DTH1_k127_5269679_12 - - - - 0.0000000000000000000000000000001047 130.0
DTH1_k127_5269679_13 - - - - 0.0000000000000000000000000007405 114.0
DTH1_k127_5269679_14 nucleoside-diphosphate sugar epimerase K07071 - - 0.00001102 49.0
DTH1_k127_5269679_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 383.0
DTH1_k127_5269679_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 369.0
DTH1_k127_5269679_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 356.0
DTH1_k127_5269679_5 Ferritin Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 294.0
DTH1_k127_5269679_6 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007739 242.0
DTH1_k127_5269679_7 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000001842 213.0
DTH1_k127_5269679_8 - - - - 0.0000000000000000000000000000000000000000000000007027 181.0
DTH1_k127_5269679_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000001025 163.0
DTH1_k127_528543_0 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005312 270.0
DTH1_k127_528543_1 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000007168 244.0
DTH1_k127_528543_2 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000001077 224.0
DTH1_k127_528543_3 AMP binding - - - 0.000000000000000000000000000000000000000006365 167.0
DTH1_k127_5353220_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1680.0
DTH1_k127_5353220_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 2.357e-298 931.0
DTH1_k127_5353220_10 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
DTH1_k127_5353220_11 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 299.0
DTH1_k127_5353220_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002137 273.0
DTH1_k127_5353220_13 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005504 265.0
DTH1_k127_5353220_14 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000002535 219.0
DTH1_k127_5353220_15 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000001585 210.0
DTH1_k127_5353220_16 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000002899 176.0
DTH1_k127_5353220_17 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000007286 164.0
DTH1_k127_5353220_18 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000001195 149.0
DTH1_k127_5353220_19 Enzyme of the cupin superfamily K06995 - - 0.000000000000000000000000000000003167 130.0
DTH1_k127_5353220_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.353e-195 618.0
DTH1_k127_5353220_20 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000001884 109.0
DTH1_k127_5353220_21 PFAM Major Facilitator Superfamily K08177 - - 0.0000000000000116 76.0
DTH1_k127_5353220_22 - - - - 0.00000000001131 66.0
DTH1_k127_5353220_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 633.0
DTH1_k127_5353220_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 461.0
DTH1_k127_5353220_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 382.0
DTH1_k127_5353220_6 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 370.0
DTH1_k127_5353220_7 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 387.0
DTH1_k127_5353220_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 351.0
DTH1_k127_5353220_9 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 350.0
DTH1_k127_5451472_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.061e-279 872.0
DTH1_k127_5451472_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 509.0
DTH1_k127_5451472_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 438.0
DTH1_k127_5451472_3 PFAM Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 402.0
DTH1_k127_5451472_4 Radical SAM K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000004012 236.0
DTH1_k127_5451472_5 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000007003 226.0
DTH1_k127_5451472_6 beta-galactosidase activity K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000428 219.0
DTH1_k127_5451472_7 4Fe-4S single cluster domain - - - 0.00000000001127 75.0
DTH1_k127_5526740_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1097.0
DTH1_k127_5526740_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 376.0
DTH1_k127_5526740_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000958 139.0
DTH1_k127_5526740_5 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000001864 82.0
DTH1_k127_5526740_6 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000003002 84.0
DTH1_k127_5614917_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.775e-200 637.0
DTH1_k127_5614917_1 Ftsk_gamma K03466 - - 2.105e-197 637.0
DTH1_k127_5614917_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 281.0
DTH1_k127_5614917_11 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.0000000000000000000000000000000000000000001829 164.0
DTH1_k127_5614917_12 Kelch motif - - - 0.0000000000000000000000000000000000008078 149.0
DTH1_k127_5614917_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 611.0
DTH1_k127_5614917_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 584.0
DTH1_k127_5614917_4 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 550.0
DTH1_k127_5614917_5 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 490.0
DTH1_k127_5614917_6 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 372.0
DTH1_k127_5614917_7 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 369.0
DTH1_k127_5614917_8 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 305.0
DTH1_k127_5614917_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
DTH1_k127_5831947_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.291e-288 894.0
DTH1_k127_5831947_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.627e-227 733.0
DTH1_k127_5831947_10 HNH nucleases - - - 0.000000000000000000000000000000000003628 139.0
DTH1_k127_5831947_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000005323 137.0
DTH1_k127_5831947_12 General secretion pathway protein D K02453 - - 0.0000000000000000000000000002665 130.0
DTH1_k127_5831947_13 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000002749 115.0
DTH1_k127_5831947_14 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00000000000000000007367 91.0
DTH1_k127_5831947_15 Domain of unknown function (DUF4912) K09942 - - 0.0000000000007043 80.0
DTH1_k127_5831947_16 - - - - 0.000003578 49.0
DTH1_k127_5831947_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.244e-217 683.0
DTH1_k127_5831947_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 7.945e-201 635.0
DTH1_k127_5831947_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.109e-200 634.0
DTH1_k127_5831947_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 481.0
DTH1_k127_5831947_6 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 367.0
DTH1_k127_5831947_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 377.0
DTH1_k127_5831947_8 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001288 272.0
DTH1_k127_5831947_9 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000002678 232.0
DTH1_k127_5868203_0 Domain of unknown function (DUF4139) - - - 1.099e-196 624.0
DTH1_k127_5868203_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 572.0
DTH1_k127_5868203_10 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000245 221.0
DTH1_k127_5868203_11 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000006345 172.0
DTH1_k127_5868203_12 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000007141 139.0
DTH1_k127_5868203_13 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000006893 89.0
DTH1_k127_5868203_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 496.0
DTH1_k127_5868203_3 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 432.0
DTH1_k127_5868203_4 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 436.0
DTH1_k127_5868203_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 409.0
DTH1_k127_5868203_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 396.0
DTH1_k127_5868203_7 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 363.0
DTH1_k127_5868203_8 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007894 272.0
DTH1_k127_5868203_9 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005789 250.0
DTH1_k127_5870032_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 551.0
DTH1_k127_5870032_1 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 412.0
DTH1_k127_5870032_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 366.0
DTH1_k127_5870032_3 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000001055 216.0
DTH1_k127_5870032_4 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000004306 188.0
DTH1_k127_5870032_5 PFAM Fimbrial assembly K02461 - - 0.00000000000000000000000001283 125.0
DTH1_k127_5870032_6 Type II secretion system (T2SS), protein M subtype b - - - 0.00000000001731 72.0
DTH1_k127_5870032_7 pilus assembly protein PilW K02459,K02672 - - 0.000000002646 67.0
DTH1_k127_5870032_8 Prokaryotic N-terminal methylation motif K02458 - - 0.0000007102 58.0
DTH1_k127_5870032_9 Prokaryotic N-terminal methylation motif K02457 - - 0.00001881 53.0
DTH1_k127_5880942_0 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 488.0
DTH1_k127_5880942_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 396.0
DTH1_k127_5880942_2 helix_turn_helix gluconate operon transcriptional repressor K03710 - - 0.0000000007831 61.0
DTH1_k127_5913499_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 416.0
DTH1_k127_5913499_1 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 370.0
DTH1_k127_5913499_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000004911 202.0
DTH1_k127_5913499_3 Histidine kinase - - - 0.0000000000000000000177 96.0
DTH1_k127_5913499_4 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000002752 92.0
DTH1_k127_5913499_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000007135 93.0
DTH1_k127_5931707_0 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 328.0
DTH1_k127_5931707_1 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000242 237.0
DTH1_k127_5931707_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000006167 163.0
DTH1_k127_5931707_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000001814 156.0
DTH1_k127_6025093_0 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 398.0
DTH1_k127_6025093_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 285.0
DTH1_k127_6025093_2 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009885 292.0
DTH1_k127_6025093_3 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000006484 208.0
DTH1_k127_6025093_4 Membrane - - - 0.0000000000006282 77.0
DTH1_k127_6035623_0 FAD binding domain K00278 - 1.4.3.16 1.45e-204 652.0
DTH1_k127_6035623_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 444.0
DTH1_k127_6035623_10 Peptidase family M48 - - - 0.00000000000000000000000000000000000001423 148.0
DTH1_k127_6035623_11 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000003562 113.0
DTH1_k127_6035623_12 chaperone-mediated protein folding - - - 0.000000000000000001135 94.0
DTH1_k127_6035623_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 416.0
DTH1_k127_6035623_3 binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 412.0
DTH1_k127_6035623_4 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004039 265.0
DTH1_k127_6035623_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
DTH1_k127_6035623_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000006214 210.0
DTH1_k127_6035623_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001527 207.0
DTH1_k127_6035623_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000009743 179.0
DTH1_k127_6035623_9 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000005791 175.0
DTH1_k127_6314847_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3.208e-280 872.0
DTH1_k127_6314847_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 434.0
DTH1_k127_6314847_2 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 268.0
DTH1_k127_6314847_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000002481 246.0
DTH1_k127_6314847_5 gas vesicle protein - - - 0.0000000000000000000001198 101.0
DTH1_k127_6314847_6 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000007961 68.0
DTH1_k127_6409709_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 391.0
DTH1_k127_6409709_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002107 243.0
DTH1_k127_6409709_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000001059 213.0
DTH1_k127_6409709_3 - K07275 - - 0.000000000000000001174 93.0
DTH1_k127_6428300_0 PFAM ferredoxin-dependent glutamate synthase - - - 2.804e-294 908.0
DTH1_k127_6428300_1 Conserved region in glutamate synthase - - - 7.398e-273 846.0
DTH1_k127_6428300_10 PFAM Radical SAM domain protein K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000003829 248.0
DTH1_k127_6428300_11 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.000000000000000000000000000000000000000000127 167.0
DTH1_k127_6428300_12 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000005684 105.0
DTH1_k127_6428300_2 L-glutamate biosynthetic process - - - 2.192e-197 619.0
DTH1_k127_6428300_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 499.0
DTH1_k127_6428300_4 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 429.0
DTH1_k127_6428300_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 400.0
DTH1_k127_6428300_6 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 396.0
DTH1_k127_6428300_7 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 396.0
DTH1_k127_6428300_8 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 377.0
DTH1_k127_6428300_9 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005064 271.0
DTH1_k127_6479525_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.825e-246 785.0
DTH1_k127_6479525_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 546.0
DTH1_k127_6479525_2 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 339.0
DTH1_k127_6479525_3 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.000000000000000005589 90.0
DTH1_k127_6556623_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 490.0
DTH1_k127_6556623_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 466.0
DTH1_k127_6556623_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000005354 189.0
DTH1_k127_6556623_11 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000003079 185.0
DTH1_k127_6556623_12 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000000000001187 153.0
DTH1_k127_6556623_13 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.00000000000000000000000000000000000001375 156.0
DTH1_k127_6556623_14 COG1522 Transcriptional regulators - - - 0.00000000000005711 74.0
DTH1_k127_6556623_15 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000002332 52.0
DTH1_k127_6556623_16 Sporulation related domain - - - 0.000006251 56.0
DTH1_k127_6556623_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 306.0
DTH1_k127_6556623_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 307.0
DTH1_k127_6556623_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 263.0
DTH1_k127_6556623_5 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
DTH1_k127_6556623_6 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004035 243.0
DTH1_k127_6556623_7 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000001309 224.0
DTH1_k127_6556623_8 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000003251 218.0
DTH1_k127_6556623_9 Fumarase C-terminus K01676,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000003076 188.0
DTH1_k127_6703065_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 353.0
DTH1_k127_6801225_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 609.0
DTH1_k127_6801225_1 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 553.0
DTH1_k127_6801225_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000001952 223.0
DTH1_k127_6801225_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000005368 186.0
DTH1_k127_6801225_4 SMART Rhodanese domain protein - - - 0.000000000000000000000000004171 114.0
DTH1_k127_6848162_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 366.0
DTH1_k127_6848162_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 292.0
DTH1_k127_6848162_2 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000007716 231.0
DTH1_k127_6848162_3 mechanosensitive ion channel - - - 0.00000000004642 66.0
DTH1_k127_7037438_0 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000000000000000000001467 169.0
DTH1_k127_7037438_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000006323 150.0
DTH1_k127_7037438_2 PFAM ribosomal protein S8E K02995 - - 0.000000000000000000000008898 100.0
DTH1_k127_7037438_3 - - - - 0.00006767 49.0
DTH1_k127_7103352_0 PFAM response regulator receiver - - - 0.0000000000000000000000000003016 118.0
DTH1_k127_7103352_1 PAS domain - - - 0.000000000000000000000000792 110.0
DTH1_k127_7141745_0 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 610.0
DTH1_k127_7141745_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 520.0
DTH1_k127_7162141_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1094.0
DTH1_k127_7162141_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1072.0
DTH1_k127_7162141_10 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 366.0
DTH1_k127_7162141_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 336.0
DTH1_k127_7162141_12 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 329.0
DTH1_k127_7162141_13 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 289.0
DTH1_k127_7162141_14 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008234 281.0
DTH1_k127_7162141_15 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
DTH1_k127_7162141_16 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004319 268.0
DTH1_k127_7162141_17 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000717 255.0
DTH1_k127_7162141_18 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000001634 241.0
DTH1_k127_7162141_19 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000003133 233.0
DTH1_k127_7162141_2 1,4-alpha-glucan branching enzyme activity K00700,K01187,K01236,K17734 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 1e-322 1002.0
DTH1_k127_7162141_20 ATP cone domain - - - 0.000000000000000000000000000000000000000000000000000000000000001349 228.0
DTH1_k127_7162141_21 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
DTH1_k127_7162141_22 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000006075 203.0
DTH1_k127_7162141_23 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000000000005403 177.0
DTH1_k127_7162141_24 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000007025 168.0
DTH1_k127_7162141_26 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000003989 166.0
DTH1_k127_7162141_27 Thioredoxin-like - - - 0.0000000000000000000000000000000004633 137.0
DTH1_k127_7162141_28 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000002866 132.0
DTH1_k127_7162141_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000001536 132.0
DTH1_k127_7162141_3 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 3.952e-228 724.0
DTH1_k127_7162141_30 NusG domain II - - - 0.000000000000002609 80.0
DTH1_k127_7162141_31 - - - - 0.00000000000002762 75.0
DTH1_k127_7162141_32 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000002865 70.0
DTH1_k127_7162141_34 COG NOG19146 non supervised orthologous group - - - 0.0000817 47.0
DTH1_k127_7162141_35 Protein of unknown function (DUF1573) - - - 0.0001454 46.0
DTH1_k127_7162141_37 - - - - 0.0003341 44.0
DTH1_k127_7162141_4 GAF domain - - - 1.134e-203 660.0
DTH1_k127_7162141_5 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 542.0
DTH1_k127_7162141_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 483.0
DTH1_k127_7162141_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 454.0
DTH1_k127_7162141_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 376.0
DTH1_k127_7162141_9 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 377.0
DTH1_k127_716964_0 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1014.0
DTH1_k127_716964_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.601e-314 975.0
DTH1_k127_716964_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000012 130.0
DTH1_k127_716964_11 Thiamine-binding protein - - - 0.0000000000000000000000000000006309 125.0
DTH1_k127_716964_2 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 9.493e-273 864.0
DTH1_k127_716964_3 DNA polymerase K02347 - - 9.906e-234 735.0
DTH1_k127_716964_4 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 7.024e-197 621.0
DTH1_k127_716964_5 FAD binding domain K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 591.0
DTH1_k127_716964_6 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 514.0
DTH1_k127_716964_7 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 405.0
DTH1_k127_716964_8 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
DTH1_k127_716964_9 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 298.0
DTH1_k127_7208551_0 PFAM Radical SAM - - - 8.345e-220 694.0
DTH1_k127_7208551_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 561.0
DTH1_k127_7208551_2 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 541.0
DTH1_k127_7208551_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
DTH1_k127_7208551_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 314.0
DTH1_k127_7208551_5 - - - - 0.000000000000000000000000000000000000000000000000003665 185.0
DTH1_k127_7208551_6 HIT domain K02503 - - 0.000000000000000000000000000000000000000002581 160.0
DTH1_k127_7208551_7 SNARE associated Golgi protein - - - 0.0000000000000000000000009538 111.0
DTH1_k127_7208551_8 4Fe-4S binding domain - - - 0.00000000000000000000002276 100.0
DTH1_k127_7400746_0 Telomere recombination K04656 - - 8.972e-226 724.0
DTH1_k127_7400746_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 447.0
DTH1_k127_7505382_0 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 604.0
DTH1_k127_7505382_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 587.0
DTH1_k127_7505382_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 503.0
DTH1_k127_7505382_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 328.0
DTH1_k127_7505382_4 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000001065 169.0
DTH1_k127_7505382_5 Transcription factor zinc-finger - - - 0.0000000000000000000000001275 113.0
DTH1_k127_7505382_7 von Willebrand factor, type A - - - 0.0000001793 59.0
DTH1_k127_7596623_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000387 167.0
DTH1_k127_7596623_1 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000003493 137.0
DTH1_k127_7596623_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000001092 58.0
DTH1_k127_7598586_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1114.0
DTH1_k127_7598586_1 Transport of potassium into the cell K03549 - - 2.078e-241 760.0
DTH1_k127_7598586_10 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000001479 185.0
DTH1_k127_7598586_12 response regulator - - - 0.00000000000000000000000000000001888 139.0
DTH1_k127_7598586_13 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000002493 99.0
DTH1_k127_7598586_14 - - - - 0.00000000000002104 74.0
DTH1_k127_7598586_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.897e-200 640.0
DTH1_k127_7598586_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 550.0
DTH1_k127_7598586_4 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 421.0
DTH1_k127_7598586_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 326.0
DTH1_k127_7598586_6 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001942 284.0
DTH1_k127_7598586_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 280.0
DTH1_k127_7598586_8 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000007014 241.0
DTH1_k127_7598586_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000001744 241.0
DTH1_k127_7602393_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.893e-244 759.0
DTH1_k127_7602393_1 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 301.0
DTH1_k127_7602393_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000002596 177.0
DTH1_k127_7602393_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000002979 105.0
DTH1_k127_7623821_0 COG0058 Glucan phosphorylase - - - 7.456e-255 796.0
DTH1_k127_7623821_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.111e-202 638.0
DTH1_k127_7623821_10 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000004157 211.0
DTH1_k127_7623821_11 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000004074 216.0
DTH1_k127_7623821_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000004037 191.0
DTH1_k127_7623821_14 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000001479 178.0
DTH1_k127_7623821_15 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000003793 148.0
DTH1_k127_7623821_16 Domain of unknown function (DUF4388) - - - 0.0000000000000000000006301 105.0
DTH1_k127_7623821_18 protein secretion K03116,K03117 - - 0.0000000000001241 75.0
DTH1_k127_7623821_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 524.0
DTH1_k127_7623821_3 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 494.0
DTH1_k127_7623821_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 389.0
DTH1_k127_7623821_5 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 389.0
DTH1_k127_7623821_6 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 348.0
DTH1_k127_7623821_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 346.0
DTH1_k127_7623821_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 334.0
DTH1_k127_7623821_9 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 290.0
DTH1_k127_7638816_0 Glycosyl hydrolase family 57 - - - 2.235e-225 719.0
DTH1_k127_7638816_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.758e-199 624.0
DTH1_k127_7638816_10 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000003113 207.0
DTH1_k127_7638816_11 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000006486 199.0
DTH1_k127_7638816_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000001128 180.0
DTH1_k127_7638816_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000001583 161.0
DTH1_k127_7638816_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000003131 161.0
DTH1_k127_7638816_15 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000003759 151.0
DTH1_k127_7638816_16 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000006432 141.0
DTH1_k127_7638816_17 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000267 128.0
DTH1_k127_7638816_19 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000004402 90.0
DTH1_k127_7638816_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 466.0
DTH1_k127_7638816_20 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.00000000000001213 89.0
DTH1_k127_7638816_21 cell cycle K05589,K12065,K13052 - - 0.00000000000002644 76.0
DTH1_k127_7638816_22 Polyketide cyclase / dehydrase and lipid transport - - - 0.0003 49.0
DTH1_k127_7638816_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 456.0
DTH1_k127_7638816_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 436.0
DTH1_k127_7638816_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 428.0
DTH1_k127_7638816_6 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 401.0
DTH1_k127_7638816_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 368.0
DTH1_k127_7638816_8 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000004811 265.0
DTH1_k127_7638816_9 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
DTH1_k127_785074_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 571.0
DTH1_k127_785074_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 530.0
DTH1_k127_785074_10 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004896 248.0
DTH1_k127_785074_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000005371 227.0
DTH1_k127_785074_12 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000002479 187.0
DTH1_k127_785074_13 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001054 163.0
DTH1_k127_785074_14 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001292 149.0
DTH1_k127_785074_15 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000004362 147.0
DTH1_k127_785074_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000005831 122.0
DTH1_k127_785074_17 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000007075 114.0
DTH1_k127_785074_18 AMP binding - - - 0.0000001319 53.0
DTH1_k127_785074_19 Part of a membrane complex involved in electron transport K03613 - - 0.0000002247 53.0
DTH1_k127_785074_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 483.0
DTH1_k127_785074_20 electron transfer activity K03616 - - 0.00006949 48.0
DTH1_k127_785074_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 478.0
DTH1_k127_785074_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 392.0
DTH1_k127_785074_5 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 323.0
DTH1_k127_785074_6 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 291.0
DTH1_k127_785074_7 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003725 279.0
DTH1_k127_785074_8 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001131 255.0
DTH1_k127_785074_9 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
DTH1_k127_7951679_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.439e-253 793.0
DTH1_k127_7951679_1 PFAM Type II secretion system protein E K02454 - - 1.327e-197 627.0
DTH1_k127_7951679_10 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000956 167.0
DTH1_k127_7951679_11 SMART PDZ DHR GLGF domain protein K02452 - - 0.00000000000000000000000000000000000000001458 164.0
DTH1_k127_7951679_12 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000008756 144.0
DTH1_k127_7951679_13 Belongs to the peptidase S8 family - - - 0.000000000000000000000000001134 122.0
DTH1_k127_7951679_14 - - - - 0.0000000000000000002223 97.0
DTH1_k127_7951679_16 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000003634 78.0
DTH1_k127_7951679_17 CAAX protease self-immunity - - - 0.000000009133 64.0
DTH1_k127_7951679_18 Prokaryotic N-terminal methylation motif K02458 - - 0.0000003356 59.0
DTH1_k127_7951679_19 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.00001449 54.0
DTH1_k127_7951679_2 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 546.0
DTH1_k127_7951679_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 464.0
DTH1_k127_7951679_4 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 438.0
DTH1_k127_7951679_5 Subtilase family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 344.0
DTH1_k127_7951679_6 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 296.0
DTH1_k127_7951679_7 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004305 273.0
DTH1_k127_7951679_8 Type II secretory pathway K02653 - - 0.0000000000000000000000000000000000000000000000000000000000006765 225.0
DTH1_k127_7951679_9 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000002101 211.0
DTH1_k127_7977214_0 TRCF K03723 - - 2.72e-232 754.0
DTH1_k127_7977214_1 4Fe-4S binding domain - - - 5.755e-205 653.0
DTH1_k127_7977214_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 437.0
DTH1_k127_7977214_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 377.0
DTH1_k127_7977214_4 - - - - 0.00000000000000000000000000000000000000000000000000134 190.0
DTH1_k127_7977214_5 TPR repeat - - - 0.000000000000000000003854 102.0
DTH1_k127_8103154_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.185e-247 767.0
DTH1_k127_8103154_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 5.018e-213 671.0
DTH1_k127_8103154_10 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004811 256.0
DTH1_k127_8103154_11 to the N-terminal region of K07491 - - 0.000000000000000000000000000000000000000000000000436 178.0
DTH1_k127_8103154_12 YbbR-like protein - - - 0.000000000000000000000000000000000000000000000483 174.0
DTH1_k127_8103154_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001311 74.0
DTH1_k127_8103154_15 - - - - 0.00000001221 61.0
DTH1_k127_8103154_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 539.0
DTH1_k127_8103154_3 Glycosyl transferase family 21 K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 445.0
DTH1_k127_8103154_4 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 398.0
DTH1_k127_8103154_5 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 352.0
DTH1_k127_8103154_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 342.0
DTH1_k127_8103154_7 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 362.0
DTH1_k127_8103154_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 289.0
DTH1_k127_8103154_9 cellulose synthase operon protein YhjU - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001129 296.0
DTH1_k127_8109518_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1111.0
DTH1_k127_8109518_1 Elongation factor G, domain IV K02355 - - 2.098e-309 961.0
DTH1_k127_8109518_10 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 332.0
DTH1_k127_8109518_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 321.0
DTH1_k127_8109518_12 proteolysis K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000004265 231.0
DTH1_k127_8109518_13 diguanylate cyclase - - - 0.000000000000000000000000000000000000000001212 172.0
DTH1_k127_8109518_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000007609 136.0
DTH1_k127_8109518_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000001761 137.0
DTH1_k127_8109518_16 - K07275 - - 0.00000000000000000000016 99.0
DTH1_k127_8109518_17 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000004552 54.0
DTH1_k127_8109518_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.219e-271 842.0
DTH1_k127_8109518_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.03e-248 773.0
DTH1_k127_8109518_4 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 594.0
DTH1_k127_8109518_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 582.0
DTH1_k127_8109518_6 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 483.0
DTH1_k127_8109518_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 461.0
DTH1_k127_8109518_8 - K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 425.0
DTH1_k127_8109518_9 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 333.0
DTH1_k127_8155196_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 451.0
DTH1_k127_8155196_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 450.0
DTH1_k127_8155196_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000387 194.0
DTH1_k127_8155196_11 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000003909 189.0
DTH1_k127_8155196_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000003407 178.0
DTH1_k127_8155196_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 390.0
DTH1_k127_8155196_3 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 326.0
DTH1_k127_8155196_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 304.0
DTH1_k127_8155196_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000004202 255.0
DTH1_k127_8155196_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000002637 233.0
DTH1_k127_8155196_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000466 231.0
DTH1_k127_8155196_8 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000143 214.0
DTH1_k127_8155196_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007394 211.0
DTH1_k127_8295391_0 teichoic acid transport K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 291.0
DTH1_k127_8295391_1 ABC-2 type transporter K09688,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
DTH1_k127_8295391_2 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000006387 214.0
DTH1_k127_8325485_0 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 540.0
DTH1_k127_8325485_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 518.0
DTH1_k127_8325485_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 464.0
DTH1_k127_8325485_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 416.0
DTH1_k127_8325485_4 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 343.0
DTH1_k127_8325485_5 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 338.0
DTH1_k127_8325485_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000001555 214.0
DTH1_k127_8325485_7 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000009004 164.0
DTH1_k127_8325485_8 Universal stress protein family - - - 0.00000000000000000000000237 108.0
DTH1_k127_8325485_9 RDD family - - - 0.00000000000000000000003164 104.0
DTH1_k127_8326712_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 3.452e-234 742.0
DTH1_k127_8326712_1 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 1.572e-215 679.0
DTH1_k127_8326712_10 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 437.0
DTH1_k127_8326712_11 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
DTH1_k127_8326712_12 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 356.0
DTH1_k127_8326712_13 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 301.0
DTH1_k127_8326712_14 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 285.0
DTH1_k127_8326712_15 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003544 274.0
DTH1_k127_8326712_16 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003707 274.0
DTH1_k127_8326712_17 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
DTH1_k127_8326712_18 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007945 253.0
DTH1_k127_8326712_19 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000002285 233.0
DTH1_k127_8326712_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.214e-207 653.0
DTH1_k127_8326712_20 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
DTH1_k127_8326712_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000005922 226.0
DTH1_k127_8326712_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001313 209.0
DTH1_k127_8326712_23 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000003349 198.0
DTH1_k127_8326712_24 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000003021 180.0
DTH1_k127_8326712_25 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000002547 178.0
DTH1_k127_8326712_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000962 175.0
DTH1_k127_8326712_27 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000005666 169.0
DTH1_k127_8326712_28 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000004948 168.0
DTH1_k127_8326712_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000008003 142.0
DTH1_k127_8326712_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.701e-199 632.0
DTH1_k127_8326712_30 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000001471 133.0
DTH1_k127_8326712_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000008708 116.0
DTH1_k127_8326712_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000007609 63.0
DTH1_k127_8326712_34 Putative prokaryotic signal transducing protein - - - 0.000946 44.0
DTH1_k127_8326712_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 608.0
DTH1_k127_8326712_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 521.0
DTH1_k127_8326712_6 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 469.0
DTH1_k127_8326712_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 467.0
DTH1_k127_8326712_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 447.0
DTH1_k127_8326712_9 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 446.0
DTH1_k127_8760808_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.303e-231 722.0
DTH1_k127_8760808_1 Elongation factor SelB, winged helix K03833 - - 6.866e-218 692.0
DTH1_k127_8760808_10 protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000001386 185.0
DTH1_k127_8760808_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000004963 171.0
DTH1_k127_8760808_12 nucleotide metabolic process - - - 0.0000000000000000000000000000000000003842 149.0
DTH1_k127_8760808_13 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.00000000000000000000000001321 119.0
DTH1_k127_8760808_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000003881 117.0
DTH1_k127_8760808_15 Protein of unknown function (DUF2845) - - - 0.0000000000000001362 84.0
DTH1_k127_8760808_2 Bacterial protein of unknown function (DUF853) K06915 - - 2.161e-209 660.0
DTH1_k127_8760808_3 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 493.0
DTH1_k127_8760808_4 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 415.0
DTH1_k127_8760808_5 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 373.0
DTH1_k127_8760808_6 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 330.0
DTH1_k127_8760808_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
DTH1_k127_8760808_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000002594 197.0
DTH1_k127_8760808_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000006798 197.0
DTH1_k127_8933076_0 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 569.0
DTH1_k127_8933076_1 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 512.0
DTH1_k127_8933076_10 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000006505 172.0
DTH1_k127_8933076_11 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000007124 172.0
DTH1_k127_8933076_12 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000181 170.0
DTH1_k127_8933076_13 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000003387 134.0
DTH1_k127_8933076_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000009949 110.0
DTH1_k127_8933076_16 Protein of unknown function (DUF507) - - - 0.0000000000000000000000001737 108.0
DTH1_k127_8933076_17 Protein of unknown function (DUF507) - - - 0.0000000000000000000000001792 109.0
DTH1_k127_8933076_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001559 104.0
DTH1_k127_8933076_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 367.0
DTH1_k127_8933076_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 356.0
DTH1_k127_8933076_4 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 331.0
DTH1_k127_8933076_5 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
DTH1_k127_8933076_6 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003858 273.0
DTH1_k127_8933076_7 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 257.0
DTH1_k127_8933076_8 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000003681 220.0
DTH1_k127_8933076_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000006269 186.0
DTH1_k127_9124352_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1037.0
DTH1_k127_9124352_1 carbon starvation protein CstA K06200 - - 7.917e-302 936.0
DTH1_k127_9124352_10 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 426.0
DTH1_k127_9124352_11 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 422.0
DTH1_k127_9124352_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 400.0
DTH1_k127_9124352_13 radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 388.0
DTH1_k127_9124352_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 387.0
DTH1_k127_9124352_15 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 379.0
DTH1_k127_9124352_16 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 379.0
DTH1_k127_9124352_17 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 359.0
DTH1_k127_9124352_18 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 366.0
DTH1_k127_9124352_19 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 343.0
DTH1_k127_9124352_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.247e-286 888.0
DTH1_k127_9124352_20 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 325.0
DTH1_k127_9124352_21 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 342.0
DTH1_k127_9124352_22 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 304.0
DTH1_k127_9124352_23 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 314.0
DTH1_k127_9124352_24 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008393 284.0
DTH1_k127_9124352_25 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008723 273.0
DTH1_k127_9124352_26 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007309 275.0
DTH1_k127_9124352_27 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000004796 258.0
DTH1_k127_9124352_28 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001433 258.0
DTH1_k127_9124352_29 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000001651 253.0
DTH1_k127_9124352_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.967e-284 900.0
DTH1_k127_9124352_30 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000004774 269.0
DTH1_k127_9124352_31 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000004762 243.0
DTH1_k127_9124352_32 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007625 242.0
DTH1_k127_9124352_33 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000002259 242.0
DTH1_k127_9124352_34 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000001437 242.0
DTH1_k127_9124352_35 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000463 223.0
DTH1_k127_9124352_36 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000002088 222.0
DTH1_k127_9124352_37 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000166 220.0
DTH1_k127_9124352_38 Histidine kinase K02668,K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002924 226.0
DTH1_k127_9124352_39 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000003988 216.0
DTH1_k127_9124352_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.985e-232 731.0
DTH1_k127_9124352_40 nucleotide catabolic process - - - 0.00000000000000000000000000000000000000000000000000004414 191.0
DTH1_k127_9124352_41 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000005793 189.0
DTH1_k127_9124352_42 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000003791 179.0
DTH1_k127_9124352_43 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000003077 171.0
DTH1_k127_9124352_44 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000001114 169.0
DTH1_k127_9124352_45 Response regulator, receiver K11443 - - 0.00000000000000000000000000000000000000000001218 165.0
DTH1_k127_9124352_46 - - - - 0.00000000000000000000000000000000000000000003764 168.0
DTH1_k127_9124352_47 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000007615 168.0
DTH1_k127_9124352_48 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000005974 160.0
DTH1_k127_9124352_49 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000001098 154.0
DTH1_k127_9124352_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 564.0
DTH1_k127_9124352_50 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000000000000000000000004884 145.0
DTH1_k127_9124352_51 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.0000000000000000000000000000002692 129.0
DTH1_k127_9124352_52 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000001273 126.0
DTH1_k127_9124352_53 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000001416 130.0
DTH1_k127_9124352_54 - - - - 0.00000000000000000000000001037 119.0
DTH1_k127_9124352_55 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000005898 119.0
DTH1_k127_9124352_56 Predicted RNA-binding protein - - - 0.000000000000000000001156 96.0
DTH1_k127_9124352_57 PFAM Bacterial regulatory proteins, luxR family - - - 0.000000000000000000113 91.0
DTH1_k127_9124352_58 Tetratricopeptide repeats - - - 0.00000000004932 69.0
DTH1_k127_9124352_6 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 503.0
DTH1_k127_9124352_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 480.0
DTH1_k127_9124352_8 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 452.0
DTH1_k127_9124352_9 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 435.0
DTH1_k127_9168505_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.04e-278 871.0
DTH1_k127_9168505_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.027e-217 687.0
DTH1_k127_9168505_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 425.0
DTH1_k127_9168505_11 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 415.0
DTH1_k127_9168505_12 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 427.0
DTH1_k127_9168505_13 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 385.0
DTH1_k127_9168505_14 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 350.0
DTH1_k127_9168505_15 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 332.0
DTH1_k127_9168505_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 330.0
DTH1_k127_9168505_17 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 317.0
DTH1_k127_9168505_18 Belongs to the MurCDEF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 328.0
DTH1_k127_9168505_19 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 315.0
DTH1_k127_9168505_2 Nickel-dependent hydrogenase - - - 6.312e-214 671.0
DTH1_k127_9168505_20 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 316.0
DTH1_k127_9168505_21 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 310.0
DTH1_k127_9168505_22 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 314.0
DTH1_k127_9168505_23 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
DTH1_k127_9168505_24 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 299.0
DTH1_k127_9168505_25 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 307.0
DTH1_k127_9168505_26 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
DTH1_k127_9168505_27 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 287.0
DTH1_k127_9168505_28 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000001967 246.0
DTH1_k127_9168505_29 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000001517 239.0
DTH1_k127_9168505_3 Histidine kinase - - - 7.364e-211 691.0
DTH1_k127_9168505_30 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000001184 226.0
DTH1_k127_9168505_31 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
DTH1_k127_9168505_32 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000747 216.0
DTH1_k127_9168505_33 - - - - 0.00000000000000000000000000000000000000000000000001607 182.0
DTH1_k127_9168505_34 the in vivo substrate is - - - 0.0000000000000000000000000000000000000000000000002294 187.0
DTH1_k127_9168505_35 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000001094 171.0
DTH1_k127_9168505_36 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000001852 173.0
DTH1_k127_9168505_37 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000000001048 156.0
DTH1_k127_9168505_38 Universal stress protein K06149 - - 0.0000000000000000000000000000000000402 139.0
DTH1_k127_9168505_39 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000537 141.0
DTH1_k127_9168505_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 593.0
DTH1_k127_9168505_40 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000001485 138.0
DTH1_k127_9168505_41 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000003124 134.0
DTH1_k127_9168505_42 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.000000000000000000000000000000003497 140.0
DTH1_k127_9168505_43 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000007296 130.0
DTH1_k127_9168505_44 proteolysis K03665 - - 0.000000000000000000000000000001107 127.0
DTH1_k127_9168505_45 - - - - 0.0000000000000000000000001746 107.0
DTH1_k127_9168505_46 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000003882 83.0
DTH1_k127_9168505_47 Protein of unknown function DUF72 - - - 0.00000003729 57.0
DTH1_k127_9168505_49 Tetratricopeptide repeat - - - 0.0004132 43.0
DTH1_k127_9168505_5 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 573.0
DTH1_k127_9168505_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 563.0
DTH1_k127_9168505_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 462.0
DTH1_k127_9168505_8 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 462.0
DTH1_k127_9168505_9 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 455.0
DTH1_k127_988504_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 450.0
DTH1_k127_988504_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 378.0
DTH1_k127_988504_2 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 313.0
DTH1_k127_988504_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 323.0
DTH1_k127_988504_4 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000507 280.0
DTH1_k127_988504_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000001628 263.0
DTH1_k127_988504_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000863 217.0
DTH1_k127_988504_7 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000006256 178.0
DTH1_k127_988504_8 - - - - 0.0000000000000000000000000000000000000000000000006601 183.0
DTH1_k127_988504_9 Protein conserved in bacteria K09928 - - 0.0000000000002254 75.0
DTH1_k127_9952963_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 465.0
DTH1_k127_9952963_1 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
DTH1_k127_9952963_2 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000000000000000000004492 177.0
DTH1_k127_9952963_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000001251 157.0
DTH1_k127_9952963_4 YGGT family K02221 - - 0.00000000000000000000000000000009081 128.0
DTH1_k127_9956154_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 515.0
DTH1_k127_9956154_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 472.0
DTH1_k127_9956154_10 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000001418 102.0
DTH1_k127_9956154_11 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000002684 73.0
DTH1_k127_9956154_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000003665 72.0
DTH1_k127_9956154_13 regulation of DNA repair K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000006284 72.0
DTH1_k127_9956154_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 325.0
DTH1_k127_9956154_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 317.0
DTH1_k127_9956154_4 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001914 281.0
DTH1_k127_9956154_5 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000177 179.0
DTH1_k127_9956154_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000001782 141.0
DTH1_k127_9956154_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000001939 130.0
DTH1_k127_9956154_8 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000000004442 122.0
DTH1_k127_9956154_9 MlaD protein K02067 - - 0.000000000000000000000000004216 119.0