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Overview

ID MAG00747
Name DTH1_bin.54
Sample SMP0022
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Dehalococcoidales
Family JAFGLR01
Genus JAFGLR01
Species
Assembly information
Completeness (%) 75.07
Contamination (%) 3.51
GC content (%) 50.0
N50 (bp) 3,312
Genome size (bp) 1,315,716

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1335

Gene name Description KEGG GOs EC E-value Score Sequence
DTH1_k127_10004245_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 354.0
DTH1_k127_10004245_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000002693 191.0
DTH1_k127_10057932_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 498.0
DTH1_k127_10076195_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 4.787e-211 664.0
DTH1_k127_10076195_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 423.0
DTH1_k127_10076195_2 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000000001965 134.0
DTH1_k127_10076195_3 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000263 112.0
DTH1_k127_10076195_4 Ribosomal protein S16 K02959 - - 0.00000000000000000000000003367 109.0
DTH1_k127_10076195_5 KH domain K06960 - - 0.00000000000000000000001706 101.0
DTH1_k127_10109402_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000361 255.0
DTH1_k127_1019661_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000008725 150.0
DTH1_k127_1019661_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000001762 76.0
DTH1_k127_1052271_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 458.0
DTH1_k127_1052271_1 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
DTH1_k127_1052271_2 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.000000000000000000000000000000000000000000000000000000002408 205.0
DTH1_k127_1052271_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000003129 203.0
DTH1_k127_1078876_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 281.0
DTH1_k127_109313_0 peptidase, M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008532 248.0
DTH1_k127_109313_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000005101 224.0
DTH1_k127_109313_2 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000002163 152.0
DTH1_k127_1140088_0 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006793 287.0
DTH1_k127_1145632_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 422.0
DTH1_k127_1145632_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000008082 134.0
DTH1_k127_1145632_2 HhH-GPD family K07457 - - 0.00006371 46.0
DTH1_k127_1196953_0 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 436.0
DTH1_k127_1196953_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 392.0
DTH1_k127_1196953_2 - K03975 - - 0.000003982 53.0
DTH1_k127_1201508_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 312.0
DTH1_k127_1201508_1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.00000000000000000004538 95.0
DTH1_k127_1218095_0 'Cold-shock' DNA-binding domain - - - 0.00000000000000000000000000000000000000000000004096 177.0
DTH1_k127_1218095_1 AMP binding - - - 0.0000000000000000000000001017 112.0
DTH1_k127_122655_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007381 282.0
DTH1_k127_122655_1 Putative neutral zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
DTH1_k127_122655_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000001201 151.0
DTH1_k127_122655_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000002042 128.0
DTH1_k127_1245511_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.000000000000000000000000000000000000000000000000000000000000001233 226.0
DTH1_k127_1245511_1 - - - - 0.0000006066 51.0
DTH1_k127_1281554_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 450.0
DTH1_k127_1281554_1 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 330.0
DTH1_k127_13067_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 337.0
DTH1_k127_13067_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000002934 193.0
DTH1_k127_13067_2 Glucose / Sorbosone dehydrogenase - - - 0.0000008612 61.0
DTH1_k127_132464_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.344e-205 656.0
DTH1_k127_1336394_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
DTH1_k127_1336394_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000002036 146.0
DTH1_k127_1336394_2 LuxR family transcriptional regulator K07696 - - 0.000000000000000000000000000000000001782 142.0
DTH1_k127_135696_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 535.0
DTH1_k127_135696_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 362.0
DTH1_k127_135696_2 - - - - 0.000000000000000001496 96.0
DTH1_k127_135696_3 HAD-superfamily hydrolase subfamily IA, variant 1 K01091 - 3.1.3.18 0.00007388 50.0
DTH1_k127_135696_4 type IV pilus modification protein PilV - - - 0.0001219 51.0
DTH1_k127_1368563_0 PFAM nitroreductase - - - 0.0000000000000000000000002499 113.0
DTH1_k127_1443253_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 1.283e-195 631.0
DTH1_k127_1443253_1 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000003253 267.0
DTH1_k127_1448893_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 474.0
DTH1_k127_1448893_1 cell redox homeostasis K00384,K03671 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000006342 229.0
DTH1_k127_1473553_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 589.0
DTH1_k127_1473553_1 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000008866 103.0
DTH1_k127_1473553_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000001281 74.0
DTH1_k127_1493059_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 567.0
DTH1_k127_1493059_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000355 51.0
DTH1_k127_1493059_2 Alpha-L-fucosidase - - - 0.0001746 48.0
DTH1_k127_1493836_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 582.0
DTH1_k127_1493836_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000753 143.0
DTH1_k127_1521668_0 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000008357 153.0
DTH1_k127_1521668_1 integral membrane protein - - - 0.00000000000000000000000000000000001038 147.0
DTH1_k127_1521668_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000008774 49.0
DTH1_k127_1539113_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.22e-291 905.0
DTH1_k127_1539113_1 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 572.0
DTH1_k127_1539113_2 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 298.0
DTH1_k127_1539113_3 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000002968 124.0
DTH1_k127_1551117_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000412 118.0
DTH1_k127_1551117_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000002039 89.0
DTH1_k127_155416_0 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 441.0
DTH1_k127_155416_1 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000001855 182.0
DTH1_k127_1559114_0 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000009297 146.0
DTH1_k127_1559114_1 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.00000000000000000000000000000001828 130.0
DTH1_k127_1559213_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008355 284.0
DTH1_k127_1559213_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
DTH1_k127_1559588_0 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 312.0
DTH1_k127_1559588_1 Acetyltransferase (GNAT) domain - - - 0.00000839 48.0
DTH1_k127_1563831_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 356.0
DTH1_k127_1563831_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000002999 63.0
DTH1_k127_1569923_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 260.0
DTH1_k127_1569923_1 4Fe-4S dicluster domain K00184,K07307 - - 0.0000000000132 70.0
DTH1_k127_1569923_2 Two component transcriptional regulator, winged helix family - - - 0.00000001203 56.0
DTH1_k127_1588989_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 374.0
DTH1_k127_1588989_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 349.0
DTH1_k127_1593025_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 392.0
DTH1_k127_1593025_1 Protein of unknown function DUF58 - - - 0.0003457 48.0
DTH1_k127_165817_0 Domain of unknown function (DUF1998) K06877 - - 3.498e-288 903.0
DTH1_k127_165817_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
DTH1_k127_165817_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
DTH1_k127_1672370_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 411.0
DTH1_k127_1680741_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
DTH1_k127_1680741_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000004734 167.0
DTH1_k127_1680741_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000003571 110.0
DTH1_k127_1680741_3 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.000000000005006 76.0
DTH1_k127_1699278_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 518.0
DTH1_k127_1699278_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000009981 157.0
DTH1_k127_1703573_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 391.0
DTH1_k127_1703573_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000001776 186.0
DTH1_k127_1714934_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 546.0
DTH1_k127_1714934_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 306.0
DTH1_k127_1714934_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000008932 59.0
DTH1_k127_1741314_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 552.0
DTH1_k127_1741314_1 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007411 265.0
DTH1_k127_1741314_2 Glutaredoxin K03676,K04771 - 3.4.21.107 0.000000000000000000000000000000007399 132.0
DTH1_k127_177747_0 zinc-transporting ATPase activity K02074,K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 284.0
DTH1_k127_177747_1 ABC-type metal ion transport system periplasmic component surface adhesin K09815,K11707 - - 0.0000000000000000000000000000000000000000000000000002485 191.0
DTH1_k127_1779918_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 305.0
DTH1_k127_1779918_1 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009255 275.0
DTH1_k127_1779918_2 COG1230 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000002631 245.0
DTH1_k127_1779918_3 ABC transporter substrate-binding protein - - - 0.00000000000000000006675 100.0
DTH1_k127_1779918_4 glutaredoxin-like protein, YruB-family - - - 0.000000000000000000238 88.0
DTH1_k127_181449_0 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 307.0
DTH1_k127_1819753_0 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 347.0
DTH1_k127_1819753_1 ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 312.0
DTH1_k127_1819753_2 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000001952 146.0
DTH1_k127_1827644_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 363.0
DTH1_k127_1827644_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000001478 132.0
DTH1_k127_1827644_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000006865 89.0
DTH1_k127_1848571_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 585.0
DTH1_k127_1848571_1 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000001987 98.0
DTH1_k127_1848571_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00001425 47.0
DTH1_k127_1852077_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 335.0
DTH1_k127_1852077_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000002896 231.0
DTH1_k127_1852077_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.000000000000000000000000002673 115.0
DTH1_k127_1867844_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 327.0
DTH1_k127_1867844_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 327.0
DTH1_k127_1867844_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000003879 221.0
DTH1_k127_1867844_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001133 225.0
DTH1_k127_1870827_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 425.0
DTH1_k127_1870827_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 293.0
DTH1_k127_1871544_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 319.0
DTH1_k127_1871544_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000004242 236.0
DTH1_k127_1871544_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000002144 154.0
DTH1_k127_1871544_3 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000003311 83.0
DTH1_k127_1885420_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 542.0
DTH1_k127_1885420_1 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 476.0
DTH1_k127_1885420_2 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000001826 135.0
DTH1_k127_1894896_0 Psort location Cytoplasmic, score K01262 - 3.4.11.9 0.000002568 59.0
DTH1_k127_1894896_1 proline dipeptidase activity K08688 - 3.5.3.3 0.0003341 44.0
DTH1_k127_1906882_0 Belongs to the 5'-nucleotidase family K01081,K07004,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 378.0
DTH1_k127_1906882_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000004953 140.0
DTH1_k127_1906882_2 - - - - 0.0000001355 63.0
DTH1_k127_1921162_0 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 572.0
DTH1_k127_1921162_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 325.0
DTH1_k127_1926766_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.569e-221 693.0
DTH1_k127_1935399_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 314.0
DTH1_k127_1935399_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000001849 109.0
DTH1_k127_1935399_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000108 56.0
DTH1_k127_1935399_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00001017 47.0
DTH1_k127_194262_0 Aminotransferase class I and II K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 322.0
DTH1_k127_194262_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000003608 209.0
DTH1_k127_1946702_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001961 134.0
DTH1_k127_19479_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 4.977e-223 702.0
DTH1_k127_19479_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 465.0
DTH1_k127_19479_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 427.0
DTH1_k127_19479_3 Caspase domain - - - 0.00000000000000001001 90.0
DTH1_k127_19479_4 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.00000000008905 68.0
DTH1_k127_19479_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000001626 53.0
DTH1_k127_1991472_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 305.0
DTH1_k127_1992976_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 514.0
DTH1_k127_1992976_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 505.0
DTH1_k127_1992976_2 Family of unknown function (DUF5343) - - - 0.0000000000000000000000000000000000000000000000000001972 191.0
DTH1_k127_1992976_3 - - - - 0.0000000000000000000000000004126 114.0
DTH1_k127_1996413_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 375.0
DTH1_k127_1996413_1 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000002262 205.0
DTH1_k127_1996413_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000001696 103.0
DTH1_k127_2010076_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.051e-238 745.0
DTH1_k127_2010076_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.243e-237 740.0
DTH1_k127_2010076_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000005672 117.0
DTH1_k127_2010076_11 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000008328 106.0
DTH1_k127_2010076_12 Preprotein translocase subunit K03210 - - 0.000000000000000008646 87.0
DTH1_k127_2010076_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 541.0
DTH1_k127_2010076_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 464.0
DTH1_k127_2010076_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 387.0
DTH1_k127_2010076_5 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000008301 215.0
DTH1_k127_2010076_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000003141 174.0
DTH1_k127_2010076_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000002063 158.0
DTH1_k127_2010076_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000003296 145.0
DTH1_k127_2010076_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000001881 116.0
DTH1_k127_204120_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000006956 224.0
DTH1_k127_204120_1 - - - - 0.00000000000000000000000000000000000000000001253 170.0
DTH1_k127_204120_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000001374 144.0
DTH1_k127_2101371_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000002153 213.0
DTH1_k127_2142552_0 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 324.0
DTH1_k127_2142552_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0005817 44.0
DTH1_k127_2151554_0 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 320.0
DTH1_k127_2151554_1 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.000000000000000001775 93.0
DTH1_k127_2178622_0 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000002515 174.0
DTH1_k127_2185416_0 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 465.0
DTH1_k127_2185416_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 329.0
DTH1_k127_2185416_2 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005311 248.0
DTH1_k127_2229964_0 Dak1_2 K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 537.0
DTH1_k127_2229964_1 Dodecin K09165 - - 0.000000000001419 70.0
DTH1_k127_2302060_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 295.0
DTH1_k127_2302060_1 AAA domain K07028 - - 0.00000000000000000000000000000000000004228 145.0
DTH1_k127_2380869_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 9.042e-222 697.0
DTH1_k127_2383770_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005353 283.0
DTH1_k127_2383770_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000004234 124.0
DTH1_k127_2392448_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000007011 140.0
DTH1_k127_2392448_1 Stress-responsive transcriptional regulator K03973 - - 0.0000000000000000009852 92.0
DTH1_k127_2392448_2 - - - - 0.000000000008841 76.0
DTH1_k127_2395593_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 2.876e-238 757.0
DTH1_k127_2395593_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 318.0
DTH1_k127_2395593_2 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002035 252.0
DTH1_k127_2395593_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000896 228.0
DTH1_k127_2395593_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000006332 169.0
DTH1_k127_2442547_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 310.0
DTH1_k127_2442547_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000008773 220.0
DTH1_k127_2442547_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0001219 48.0
DTH1_k127_2445207_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.539e-197 629.0
DTH1_k127_2445207_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002365 273.0
DTH1_k127_2445207_2 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000002578 224.0
DTH1_k127_2446101_0 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008813 467.0
DTH1_k127_2447800_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 418.0
DTH1_k127_2447800_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000006613 246.0
DTH1_k127_2447800_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000001024 93.0
DTH1_k127_246765_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.125e-202 644.0
DTH1_k127_246765_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 411.0
DTH1_k127_246765_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
DTH1_k127_246765_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 289.0
DTH1_k127_246765_4 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 264.0
DTH1_k127_246765_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000005967 194.0
DTH1_k127_246765_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000001067 158.0
DTH1_k127_246765_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000006625 150.0
DTH1_k127_246765_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000003329 138.0
DTH1_k127_246765_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000001654 105.0
DTH1_k127_2469414_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.273e-258 814.0
DTH1_k127_2469414_1 Iron-sulfur cluster-binding protein K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 432.0
DTH1_k127_2469414_2 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000001954 112.0
DTH1_k127_2469414_3 Phosphatidylethanolamine-binding protein - - - 0.00000000000000003033 92.0
DTH1_k127_2471866_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 308.0
DTH1_k127_2471866_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 284.0
DTH1_k127_2472647_0 Enoyl-CoA hydratase/isomerase K15866,K18474 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 0.0000000000000000000000000000000000000000000000000000000001469 213.0
DTH1_k127_2472647_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000008551 184.0
DTH1_k127_2472647_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000001112 166.0
DTH1_k127_2472647_3 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000000000000000000003161 134.0
DTH1_k127_2491889_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000005194 166.0
DTH1_k127_2491889_1 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000000000001319 98.0
DTH1_k127_2491889_2 to Saccharomyces cerevisiae JEM1 (YJL073W) K09523 GO:0000003,GO:0000741,GO:0000742,GO:0000746,GO:0000747,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0006997,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0016020,GO:0016043,GO:0019538,GO:0019941,GO:0019953,GO:0022414,GO:0030163,GO:0030433,GO:0033554,GO:0034975,GO:0034976,GO:0036503,GO:0042175,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044764,GO:0048284,GO:0050896,GO:0051082,GO:0051087,GO:0051603,GO:0051704,GO:0051716,GO:0071704,GO:0071840,GO:1901564,GO:1901565,GO:1901575,GO:1901698 - 0.0000000000007082 74.0
DTH1_k127_2533800_0 - - - - 0.0000000000000000000005372 109.0
DTH1_k127_2546719_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 8.994e-290 915.0
DTH1_k127_2546719_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001587 244.0
DTH1_k127_2546719_2 Domain of unknown function (DUF1893) - - - 0.00000006682 60.0
DTH1_k127_2546719_3 DNA integration - - - 0.000003138 50.0
DTH1_k127_2584810_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002318 282.0
DTH1_k127_2584810_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005905 240.0
DTH1_k127_2584810_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001891 246.0
DTH1_k127_2584810_3 oxidoreductase activity, acting on CH-OH group of donors K18337 - 1.1.1.173,1.1.1.377,1.1.1.378 0.0000000000000000000000000000000000000000000000000000001785 204.0
DTH1_k127_2584810_4 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000006547 203.0
DTH1_k127_2584810_5 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000005174 176.0
DTH1_k127_2584810_6 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000873 138.0
DTH1_k127_2584810_7 succinate dehydrogenase K00239 - 1.3.5.1,1.3.5.4 0.00000000000000002784 89.0
DTH1_k127_2584810_8 4Fe-4S dicluster domain - - - 0.000000000573 63.0
DTH1_k127_2612460_0 DNA-directed DNA polymerase K00960,K02337,K14162 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 0.0 1321.0
DTH1_k127_2612460_1 Transcriptional regulator, arsR family - - - 0.00000000000000000006642 93.0
DTH1_k127_2612460_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000002783 60.0
DTH1_k127_2639795_0 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 304.0
DTH1_k127_2639795_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00002838 53.0
DTH1_k127_2673386_0 Domain of unknown function (DUF2341) - - - 0.000000000000000000001078 102.0
DTH1_k127_2673386_1 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.00008835 48.0
DTH1_k127_2714672_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002063 270.0
DTH1_k127_2714672_1 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006072 263.0
DTH1_k127_2714672_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001731 255.0
DTH1_k127_2714672_3 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000001271 141.0
DTH1_k127_2714672_4 Cupin domain - - - 0.00000000000001197 79.0
DTH1_k127_2777013_0 Resolvase - - - 0.000000000000000000000000000001675 135.0
DTH1_k127_2788833_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 539.0
DTH1_k127_2788833_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 460.0
DTH1_k127_2788833_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002459 261.0
DTH1_k127_2788833_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000006764 223.0
DTH1_k127_2820132_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.623e-306 949.0
DTH1_k127_2820132_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 292.0
DTH1_k127_2822329_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 292.0
DTH1_k127_2822329_1 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000001047 208.0
DTH1_k127_2822329_2 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0004293 46.0
DTH1_k127_2848082_0 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 460.0
DTH1_k127_2848082_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000002616 173.0
DTH1_k127_2886247_0 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000001525 196.0
DTH1_k127_2886247_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000003018 162.0
DTH1_k127_2897279_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 284.0
DTH1_k127_2897279_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000003838 97.0
DTH1_k127_2897279_2 ROK family K00845 - 2.7.1.2 0.0000000000000004994 79.0
DTH1_k127_2897279_3 PFAM Cupin 2, conserved barrel - - - 0.00000000000001358 78.0
DTH1_k127_290778_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000001472 187.0
DTH1_k127_290778_1 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000004092 158.0
DTH1_k127_290778_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000002226 66.0
DTH1_k127_2956132_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 557.0
DTH1_k127_2956231_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 544.0
DTH1_k127_2956231_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 438.0
DTH1_k127_2956231_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 364.0
DTH1_k127_2956231_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000006539 224.0
DTH1_k127_2956231_4 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000001001 149.0
DTH1_k127_2956231_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000564 121.0
DTH1_k127_2965067_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 7.141e-217 691.0
DTH1_k127_2965067_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 578.0
DTH1_k127_2965067_10 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.000000000000000000000000000000000000000000168 164.0
DTH1_k127_2965067_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000004675 156.0
DTH1_k127_2965067_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000001054 153.0
DTH1_k127_2965067_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.000000000000000000000000000000001096 139.0
DTH1_k127_2965067_14 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000003199 131.0
DTH1_k127_2965067_15 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000008566 81.0
DTH1_k127_2965067_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 571.0
DTH1_k127_2965067_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 537.0
DTH1_k127_2965067_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00123,K00266 - 1.17.1.9,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 475.0
DTH1_k127_2965067_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 448.0
DTH1_k127_2965067_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 447.0
DTH1_k127_2965067_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 403.0
DTH1_k127_2965067_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000006607 249.0
DTH1_k127_2965067_9 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000002929 188.0
DTH1_k127_298520_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000001479 68.0
DTH1_k127_2995026_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 461.0
DTH1_k127_2995026_1 PFAM Cys Met metabolism, pyridoxal phosphate-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 383.0
DTH1_k127_2995026_2 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
DTH1_k127_2995026_3 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000011 228.0
DTH1_k127_2995026_4 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000002555 122.0
DTH1_k127_2995026_5 methionine transport K02071 - - 0.0000000000000001889 81.0
DTH1_k127_302164_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 557.0
DTH1_k127_302164_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000004807 203.0
DTH1_k127_302164_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000004163 207.0
DTH1_k127_302164_3 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000003516 145.0
DTH1_k127_3053833_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 481.0
DTH1_k127_3090684_0 - - - - 0.000000000000000001469 94.0
DTH1_k127_3090684_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000003637 69.0
DTH1_k127_3099355_0 fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 377.0
DTH1_k127_3099355_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000004411 147.0
DTH1_k127_3119228_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 1.505e-210 664.0
DTH1_k127_3119228_1 COG1454 Alcohol dehydrogenase, class IV - - - 0.000001833 53.0
DTH1_k127_3136852_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000101 194.0
DTH1_k127_3165288_0 - - - - 0.0000000000000000000000000000000006291 132.0
DTH1_k127_3165288_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000007082 130.0
DTH1_k127_3168367_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.79e-269 842.0
DTH1_k127_3168367_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000004067 182.0
DTH1_k127_3168367_2 Calcineurin-like phosphoesterase - - - 0.0000000001048 70.0
DTH1_k127_3222739_0 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 302.0
DTH1_k127_3222739_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000672 226.0
DTH1_k127_3222739_2 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000004223 210.0
DTH1_k127_3222739_3 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000001024 162.0
DTH1_k127_3222739_4 Cyclophilin-like K09143 - - 0.00000000000000000000000000000001968 129.0
DTH1_k127_323561_0 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 330.0
DTH1_k127_323561_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000003213 188.0
DTH1_k127_3248687_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 505.0
DTH1_k127_3248687_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000002882 96.0
DTH1_k127_3300357_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1083.0
DTH1_k127_3300357_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000008992 117.0
DTH1_k127_3331174_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 349.0
DTH1_k127_3331174_1 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003149 269.0
DTH1_k127_3331174_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000284 100.0
DTH1_k127_3331174_3 Acetyltransferase (GNAT) domain - - - 0.00000372 50.0
DTH1_k127_3331174_4 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.000005633 53.0
DTH1_k127_3331174_5 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 0.000958 45.0
DTH1_k127_3388575_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000009939 226.0
DTH1_k127_3388575_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000001493 214.0
DTH1_k127_3441215_0 KH domain K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000005032 238.0
DTH1_k127_3441215_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000002806 117.0
DTH1_k127_3441215_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000001705 110.0
DTH1_k127_3458618_0 ABC transporter, transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 542.0
DTH1_k127_3460188_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 329.0
DTH1_k127_3460188_1 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000009156 139.0
DTH1_k127_3485179_1 - - - - 0.0005029 54.0
DTH1_k127_3508402_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 301.0
DTH1_k127_3508426_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000007104 207.0
DTH1_k127_3508426_1 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000009551 166.0
DTH1_k127_3528169_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000003,GO:0000160,GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007059,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0019954,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0034622,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042254,GO:0042255,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1990904 - 0.00000000000000000000000000000000000000002797 156.0
DTH1_k127_3528169_1 Lysin motif - - - 0.00000000000000000000000002272 119.0
DTH1_k127_3546157_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000003577 237.0
DTH1_k127_3546157_1 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001663 211.0
DTH1_k127_3546157_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000001294 179.0
DTH1_k127_3546157_3 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001481 94.0
DTH1_k127_3579497_0 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 328.0
DTH1_k127_3579497_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001037 179.0
DTH1_k127_360132_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000007561 245.0
DTH1_k127_360132_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000008612 225.0
DTH1_k127_3617480_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 538.0
DTH1_k127_3617480_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.000000000000000000000000000000000000000005868 157.0
DTH1_k127_3617480_2 Peptidase C26 K01658,K01664 GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.000000000000003177 76.0
DTH1_k127_3626866_0 AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 383.0
DTH1_k127_3626866_1 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000001166 218.0
DTH1_k127_3635499_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 306.0
DTH1_k127_3635499_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000006449 158.0
DTH1_k127_3635499_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000692 142.0
DTH1_k127_3635499_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001567 81.0
DTH1_k127_3663814_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.874e-244 764.0
DTH1_k127_3663814_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.914e-225 710.0
DTH1_k127_3663814_10 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000000000009695 100.0
DTH1_k127_3663814_11 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.00000000000000000001508 93.0
DTH1_k127_3663814_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 611.0
DTH1_k127_3663814_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 474.0
DTH1_k127_3663814_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 456.0
DTH1_k127_3663814_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 423.0
DTH1_k127_3663814_6 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003233 250.0
DTH1_k127_3663814_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000001781 247.0
DTH1_k127_3663814_8 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000111 178.0
DTH1_k127_3663814_9 MgtC family K07507 - - 0.00000000000000000000000000000000001184 139.0
DTH1_k127_3699423_0 Belongs to the enoyl-CoA hydratase isomerase family - GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000001392 206.0
DTH1_k127_3699423_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000004733 172.0
DTH1_k127_3699423_2 - - - - 0.00000000000959 67.0
DTH1_k127_3699423_3 - - - - 0.000000001053 61.0
DTH1_k127_3708267_0 Biotin carboxylase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 459.0
DTH1_k127_3708267_1 Conserved carboxylase domain K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 310.0
DTH1_k127_3708506_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 498.0
DTH1_k127_3708506_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000107 252.0
DTH1_k127_3708506_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000009081 128.0
DTH1_k127_375266_0 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000004135 147.0
DTH1_k127_3762762_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 301.0
DTH1_k127_3762762_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000001026 177.0
DTH1_k127_3762762_2 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000001513 178.0
DTH1_k127_3762762_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000002096 142.0
DTH1_k127_3791643_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008727 274.0
DTH1_k127_3791643_1 serine-type aminopeptidase activity K02030,K14475 - - 0.00000000000000000000002714 104.0
DTH1_k127_3794545_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 382.0
DTH1_k127_3794545_1 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000003782 232.0
DTH1_k127_3795347_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 313.0
DTH1_k127_3795347_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000964 214.0
DTH1_k127_3795347_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000873 145.0
DTH1_k127_3795347_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000001143 136.0
DTH1_k127_3795347_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000002258 108.0
DTH1_k127_38110_0 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 6.504e-248 777.0
DTH1_k127_38110_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 348.0
DTH1_k127_38110_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
DTH1_k127_38110_3 acylphosphatase activity K01512 - 3.6.1.7 0.00000000000000000006258 92.0
DTH1_k127_4003609_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000003081 96.0
DTH1_k127_4005016_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K03520 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 312.0
DTH1_k127_4005016_1 Pyridine nucleotide-disulphide oxidoreductase K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.00000000000000000000000000000000000007836 148.0
DTH1_k127_4059873_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 612.0
DTH1_k127_4108548_0 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003976 242.0
DTH1_k127_4108548_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000009809 200.0
DTH1_k127_4108548_2 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000005303 142.0
DTH1_k127_4110808_0 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 400.0
DTH1_k127_4110808_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000002844 154.0
DTH1_k127_4111864_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 442.0
DTH1_k127_4111864_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000001366 164.0
DTH1_k127_4114837_0 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000005244 216.0
DTH1_k127_4114837_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000673 198.0
DTH1_k127_4114837_2 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000001104 68.0
DTH1_k127_4114837_3 TIGRFAM nickel ABC transporter, periplasmic nickel-binding protein K02035,K15584 - - 0.0000000006782 65.0
DTH1_k127_4118251_0 Histidine kinase - - - 0.00000006332 63.0
DTH1_k127_414674_0 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 297.0
DTH1_k127_414674_1 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003271 246.0
DTH1_k127_414674_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000005374 216.0
DTH1_k127_414674_3 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000003507 197.0
DTH1_k127_4181908_0 4 iron, 4 sulfur cluster binding - - - 0.0000000715 55.0
DTH1_k127_4181908_1 Major Facilitator Superfamily - - - 0.00000008228 61.0
DTH1_k127_4231951_0 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000000000000000001235 193.0
DTH1_k127_423403_0 Peptidase M50 - - - 0.000000000000000000000000001763 115.0
DTH1_k127_423403_1 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000002886 63.0
DTH1_k127_423403_2 Beta-lactamase superfamily domain - - - 0.000000003374 64.0
DTH1_k127_4262007_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000168 264.0
DTH1_k127_4262007_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000001689 163.0
DTH1_k127_4262007_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000002018 52.0
DTH1_k127_4274864_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004408 273.0
DTH1_k127_4274864_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000009307 201.0
DTH1_k127_4274864_2 FemAB family - - - 0.0004857 43.0
DTH1_k127_4277915_0 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 409.0
DTH1_k127_4335029_0 oxidation-reduction process - - - 1.245e-318 1003.0
DTH1_k127_4335029_1 phosphate transporter K03306 - - 0.00000000000000005637 81.0
DTH1_k127_4348623_0 Fumarate reductase flavoprotein C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 316.0
DTH1_k127_4348623_1 Metallo-beta-lactamase superfamily K05555 - - 0.00000000000000000000000000002969 122.0
DTH1_k127_4348623_2 4Fe-4S ferredoxin, iron-sulfur binding family protein - - - 0.000000000000001267 79.0
DTH1_k127_4349337_0 Transmembrane secretion effector K08217 - - 0.000000000000000000000000000000000000000000000000001217 199.0
DTH1_k127_4349337_1 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000002036 61.0
DTH1_k127_4349337_2 Trypsin - - - 0.000005122 53.0
DTH1_k127_4388591_0 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001233 256.0
DTH1_k127_4388591_1 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000525 246.0
DTH1_k127_4388591_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000005932 169.0
DTH1_k127_4388591_3 MaoC like domain - - - 0.000000000000000000000000002437 116.0
DTH1_k127_4388591_4 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000005633 107.0
DTH1_k127_4423910_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 599.0
DTH1_k127_4423910_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 472.0
DTH1_k127_4423910_2 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 364.0
DTH1_k127_4423910_3 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 350.0
DTH1_k127_4423910_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 333.0
DTH1_k127_4423910_5 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
DTH1_k127_4423910_6 NIL - - - 0.000000000000000000000000000000000000000000000000000000009142 200.0
DTH1_k127_4423910_7 PHP-associated - - - 0.00000000000000000000000000000000000000000000000000000263 198.0
DTH1_k127_4423910_8 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000009329 141.0
DTH1_k127_4423910_9 copper ion binding K03926,K16219,K17915 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0022607,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 2.1.1.244 0.00000000000001774 74.0
DTH1_k127_4458809_0 Putative Ig domain - - - 0.00000000003865 68.0
DTH1_k127_4492904_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000256 225.0
DTH1_k127_4492904_1 Rhomboid family - - - 0.000000000000000000000000000000000000000000006714 170.0
DTH1_k127_4564837_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1080.0
DTH1_k127_4564837_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 542.0
DTH1_k127_4565911_0 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000009495 260.0
DTH1_k127_4565911_1 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001624 247.0
DTH1_k127_4575774_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005639 293.0
DTH1_k127_4575774_1 acid phosphatase activity - - - 0.000000000000000000000000000000000000000001921 161.0
DTH1_k127_4575774_2 membrane K00389 - - 0.00000000000002056 76.0
DTH1_k127_4579533_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.172e-299 926.0
DTH1_k127_4579533_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001272 263.0
DTH1_k127_4579533_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000008552 178.0
DTH1_k127_458274_0 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000000000000000008389 212.0
DTH1_k127_458274_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000005707 171.0
DTH1_k127_458274_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000002318 98.0
DTH1_k127_458341_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004996 255.0
DTH1_k127_458341_1 ABC transporter substrate-binding protein - - - 0.000000000000000000000000000000000000000000000002606 193.0
DTH1_k127_4650520_0 Methyltransferase domain - - - 0.000000000000000000000000000000000003534 139.0
DTH1_k127_4650520_1 Shikimate kinase K00891 - 2.7.1.71 0.00000000000000000000000000000000001446 140.0
DTH1_k127_4716611_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000004981 237.0
DTH1_k127_4716611_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000001404 154.0
DTH1_k127_4816378_0 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 325.0
DTH1_k127_4816378_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000008155 183.0
DTH1_k127_4816378_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000005711 74.0
DTH1_k127_4831456_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 486.0
DTH1_k127_4831456_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 454.0
DTH1_k127_4831456_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000001848 216.0
DTH1_k127_4831456_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000005754 188.0
DTH1_k127_4831456_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000002097 99.0
DTH1_k127_4831456_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000003595 61.0
DTH1_k127_4831456_6 Zn-dependent hydrolases of the - - - 0.0000002997 55.0
DTH1_k127_4894394_0 E3 Ubiquitin ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 451.0
DTH1_k127_4894394_1 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 317.0
DTH1_k127_4894394_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000008578 232.0
DTH1_k127_4946462_0 pyridoxamine 5'-phosphate K07005 - - 0.00000000000002116 78.0
DTH1_k127_4993106_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003714 281.0
DTH1_k127_4993106_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000002389 92.0
DTH1_k127_4993106_2 - - - - 0.0001484 47.0
DTH1_k127_5079504_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 486.0
DTH1_k127_5079504_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000002115 128.0
DTH1_k127_509475_0 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 490.0
DTH1_k127_509475_1 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 362.0
DTH1_k127_509475_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000008253 172.0
DTH1_k127_5110145_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003942 272.0
DTH1_k127_5110145_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000001669 214.0
DTH1_k127_5120994_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 440.0
DTH1_k127_5120994_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001543 157.0
DTH1_k127_5120994_2 PFAM Uncharacterised protein, DegV family COG1307 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000001582 129.0
DTH1_k127_5143991_0 efflux protein, MATE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000191 250.0
DTH1_k127_5150729_0 AAA-like domain K06915 - - 1.324e-230 726.0
DTH1_k127_5150729_1 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 364.0
DTH1_k127_5150729_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 323.0
DTH1_k127_5150729_3 PFAM HAS barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
DTH1_k127_5150729_4 nuclease K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 0.000000000000000000000000000000000000000000000000000000000000211 221.0
DTH1_k127_5150729_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000001092 176.0
DTH1_k127_5150729_6 binds to the 23S rRNA K02939 - - 0.0000000000000000002697 92.0
DTH1_k127_5154525_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.215e-260 814.0
DTH1_k127_5154525_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004886 276.0
DTH1_k127_5162600_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 295.0
DTH1_k127_5162600_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000002981 258.0
DTH1_k127_5223785_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
DTH1_k127_5223785_1 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.0000000000000000000000000000001763 127.0
DTH1_k127_5232939_0 Terminase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 301.0
DTH1_k127_5232939_1 Band 7 protein - - - 0.0000000000000000000000001511 121.0
DTH1_k127_523480_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 550.0
DTH1_k127_523480_1 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000001039 199.0
DTH1_k127_523480_2 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000004936 102.0
DTH1_k127_5282236_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 412.0
DTH1_k127_5282236_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000000000009569 212.0
DTH1_k127_5282236_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001769 157.0
DTH1_k127_5282236_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000004639 130.0
DTH1_k127_5282236_4 IMP cyclohydrolase activity K11175 - 2.1.2.2 0.0000002974 61.0
DTH1_k127_5287152_0 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 513.0
DTH1_k127_5287152_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 324.0
DTH1_k127_5287152_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000002287 256.0
DTH1_k127_5287152_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000265 198.0
DTH1_k127_5287152_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829,K19969,K21342 - 2.7.1.71,4.2.3.152,4.2.3.154,4.2.3.4 0.000000000000001569 78.0
DTH1_k127_5287819_0 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000049 258.0
DTH1_k127_5287819_1 ThiF family - - - 0.0000001062 60.0
DTH1_k127_5291493_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 389.0
DTH1_k127_5291493_1 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 290.0
DTH1_k127_5291493_2 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.0000000000000000000000000000000000000000000000000000002206 208.0
DTH1_k127_5291493_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000004226 192.0
DTH1_k127_5291493_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000002914 80.0
DTH1_k127_5291493_5 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.000008338 49.0
DTH1_k127_5359503_0 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001052 292.0
DTH1_k127_5359503_1 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000002181 244.0
DTH1_k127_5359503_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000003845 152.0
DTH1_k127_5359503_3 Amidohydrolase K07045 - - 0.000000000000000000000000003684 115.0
DTH1_k127_5359503_4 - - - - 0.00007093 47.0
DTH1_k127_5392042_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 504.0
DTH1_k127_5392042_1 Divergent PAP2 family K09775 - - 0.00000000000000000000000000000002076 130.0
DTH1_k127_5392042_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000009315 62.0
DTH1_k127_539632_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 423.0
DTH1_k127_539632_1 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 366.0
DTH1_k127_5423216_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 347.0
DTH1_k127_5423216_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 332.0
DTH1_k127_5423216_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000003122 226.0
DTH1_k127_5423216_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000001705 192.0
DTH1_k127_5423216_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.000000000000000000000000002089 115.0
DTH1_k127_5457418_0 ABC transporter transmembrane region K06147 - - 3.72e-286 893.0
DTH1_k127_5457418_1 ABC transporter K06147 - - 0.000000000000000000007734 92.0
DTH1_k127_5457418_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000008082 89.0
DTH1_k127_5468321_0 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 377.0
DTH1_k127_5468321_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 372.0
DTH1_k127_5468321_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002337 282.0
DTH1_k127_5468321_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000003917 271.0
DTH1_k127_5468321_4 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000003246 194.0
DTH1_k127_5468321_5 - - - - 0.000000000000000000000004156 103.0
DTH1_k127_5470691_0 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 295.0
DTH1_k127_5470691_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000001508 132.0
DTH1_k127_5500730_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 4.434e-253 799.0
DTH1_k127_5500730_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 298.0
DTH1_k127_5503967_0 Fumarate reductase flavoprotein C-term - - - 0.000000000000000000000000000000000000000000001506 169.0
DTH1_k127_5503967_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000004423 99.0
DTH1_k127_5503967_2 4Fe-4S ferredoxin, iron-sulfur binding family protein - - - 0.0000000000000002727 82.0
DTH1_k127_5503967_3 - - - - 0.00001436 49.0
DTH1_k127_5508172_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000005829 177.0
DTH1_k127_5508172_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000001672 168.0
DTH1_k127_5508172_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000005048 153.0
DTH1_k127_5508172_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000009228 80.0
DTH1_k127_5508172_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000008616 54.0
DTH1_k127_5514055_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 1.3e-263 826.0
DTH1_k127_5514843_0 - - - - 0.00000000000000000000000000000000000000000000002867 182.0
DTH1_k127_5514843_1 Protein of unknown function DUF45 K07043 - - 0.000000002702 59.0
DTH1_k127_554411_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 427.0
DTH1_k127_554411_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000009118 201.0
DTH1_k127_554411_2 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000003161 184.0
DTH1_k127_5558661_0 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000009338 175.0
DTH1_k127_5558661_1 - - - - 0.00000000000000002059 84.0
DTH1_k127_5570188_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 552.0
DTH1_k127_5570188_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 390.0
DTH1_k127_5597796_0 4Fe-4S dicluster domain - - - 3.441e-230 724.0
DTH1_k127_5597796_1 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000005981 108.0
DTH1_k127_5597796_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00007233 49.0
DTH1_k127_5600393_0 Psort location Cytoplasmic, score - - - 0.0 1354.0
DTH1_k127_5600393_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000005122 237.0
DTH1_k127_5632608_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 331.0
DTH1_k127_5632608_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000144 126.0
DTH1_k127_5667966_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 582.0
DTH1_k127_5667966_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001691 247.0
DTH1_k127_5688318_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 433.0
DTH1_k127_5688318_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000001388 215.0
DTH1_k127_5759444_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 507.0
DTH1_k127_5759444_1 GYD domain - - - 0.000000000000000000000000000007551 122.0
DTH1_k127_5759444_2 Universal stress protein family - - - 0.000000000003055 72.0
DTH1_k127_5763379_0 DNA ligase K01971 - 6.5.1.1 7.505e-201 651.0
DTH1_k127_5763379_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 241.0
DTH1_k127_5769454_0 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000002182 196.0
DTH1_k127_5769454_1 denitrification pathway - - - 0.00000000000000000000000000000000001702 142.0
DTH1_k127_5775793_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005658 267.0
DTH1_k127_5775793_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000008395 68.0
DTH1_k127_5883404_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 2.768e-203 642.0
DTH1_k127_5883404_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000002136 171.0
DTH1_k127_5883404_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000008331 121.0
DTH1_k127_5883404_3 phosphatase 2c K14497 GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009787,GO:0009788,GO:0009966,GO:0009968,GO:0009987,GO:0010029,GO:0010030,GO:0010646,GO:0010648,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0023051,GO:0023057,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0048518,GO:0048519,GO:0048523,GO:0048580,GO:0048582,GO:0048583,GO:0048585,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051239,GO:0051240,GO:0065007,GO:0071704,GO:0140096,GO:1900140,GO:1901419,GO:1901420,GO:1901564,GO:1905957,GO:1905958,GO:2000026 3.1.3.16 0.0000000000000000000000001028 115.0
DTH1_k127_5883404_4 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000003174 70.0
DTH1_k127_5901411_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 497.0
DTH1_k127_5901411_1 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000007837 220.0
DTH1_k127_5901411_2 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000007324 134.0
DTH1_k127_5921786_0 HpcH/HpaI aldolase/citrate lyase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 311.0
DTH1_k127_5921786_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 296.0
DTH1_k127_5921786_2 ECF sigma factor K03088 - - 0.0000000000000000000000000001737 122.0
DTH1_k127_5921786_3 Tfp pilus assembly protein FimV - - - 0.00001802 57.0
DTH1_k127_5979531_0 Phosphatidylethanolamine-binding protein - - - 0.0000000000000000000007615 108.0
DTH1_k127_5979531_1 Phosphatidylethanolamine-binding protein K06910 - - 0.00000001965 66.0
DTH1_k127_6018087_0 Major facilitator Superfamily K08168 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 389.0
DTH1_k127_6033260_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 316.0
DTH1_k127_6033260_1 TrkA-C domain K03499 - - 0.000000000000002616 78.0
DTH1_k127_6043908_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000181 234.0
DTH1_k127_6043908_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000003089 196.0
DTH1_k127_6043908_2 electron transfer activity K05337 - - 0.000000005786 59.0
DTH1_k127_604554_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.048e-201 635.0
DTH1_k127_604554_1 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000004022 148.0
DTH1_k127_6046308_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000007917 186.0
DTH1_k127_6046308_1 Involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000000001527 183.0
DTH1_k127_6046308_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000316 44.0
DTH1_k127_6059332_0 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000001935 179.0
DTH1_k127_6083230_0 sulfur carrier activity K09004 - - 0.00000000000000000000000000000006509 126.0
DTH1_k127_6083230_1 acid phosphatase activity - - - 0.0000000000000000002303 98.0
DTH1_k127_6088322_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 487.0
DTH1_k127_6088322_1 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000002588 175.0
DTH1_k127_6088322_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000002853 67.0
DTH1_k127_6088322_3 - - - - 0.0000032 51.0
DTH1_k127_6089271_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 437.0
DTH1_k127_6089271_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 338.0
DTH1_k127_6089271_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000682 156.0
DTH1_k127_6096419_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 375.0
DTH1_k127_6096419_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000008683 231.0
DTH1_k127_6096419_2 CoA binding domain K09181 - - 0.00000005855 57.0
DTH1_k127_6100985_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
DTH1_k127_6100985_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K02003,K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000006914 220.0
DTH1_k127_6100985_2 HlyD family secretion protein K02005,K13888 - - 0.00000002682 66.0
DTH1_k127_6101206_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 4.614e-195 631.0
DTH1_k127_6101206_1 ligase activity K01474,K10854 - 3.5.2.14,6.4.1.6 0.0000000004971 62.0
DTH1_k127_6109195_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 297.0
DTH1_k127_6109195_1 AMP binding - - - 0.000000000000000000000000000000001739 134.0
DTH1_k127_6122161_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 355.0
DTH1_k127_6122161_1 AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000001069 134.0
DTH1_k127_6148926_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000004611 241.0
DTH1_k127_6148926_1 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000003314 96.0
DTH1_k127_6163076_0 DegV family - - - 0.000000000000000000000000000000000000000001589 166.0
DTH1_k127_6163076_1 Periplasmic binding protein K01999 - - 0.0005916 52.0
DTH1_k127_616760_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
DTH1_k127_616760_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 277.0
DTH1_k127_616760_2 Diguanylate cyclase - - - 0.00005644 45.0
DTH1_k127_6181096_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0 1124.0
DTH1_k127_6181096_1 Putative Fe-S cluster K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 560.0
DTH1_k127_6181096_2 Pterin binding enzyme K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 348.0
DTH1_k127_6181096_3 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000002836 93.0
DTH1_k127_6181096_4 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000007907 70.0
DTH1_k127_6184289_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 498.0
DTH1_k127_6184289_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 401.0
DTH1_k127_6184289_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 295.0
DTH1_k127_6184289_3 Methionine synthase B12-binding module cap domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001568 230.0
DTH1_k127_6184289_4 Glycosyl hydrolase family 63 C-terminal domain - - - 0.000000000000000000008882 107.0
DTH1_k127_6184289_5 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000001181 106.0
DTH1_k127_6188919_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 394.0
DTH1_k127_6188919_1 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 287.0
DTH1_k127_6188919_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 284.0
DTH1_k127_6188919_3 PFAM DegV - - - 0.000005754 49.0
DTH1_k127_6196402_0 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000571 238.0
DTH1_k127_6208146_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 538.0
DTH1_k127_6208146_1 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000005609 77.0
DTH1_k127_6215434_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 556.0
DTH1_k127_6215434_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 360.0
DTH1_k127_6215434_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 256.0
DTH1_k127_6215434_3 response regulator - - - 0.00000536 54.0
DTH1_k127_6218863_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000314 164.0
DTH1_k127_6234502_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000009971 182.0
DTH1_k127_6234502_1 Dihydroorotate dehydrogenase - - - 0.000004299 53.0
DTH1_k127_624697_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 4.908e-214 679.0
DTH1_k127_624697_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 359.0
DTH1_k127_624697_2 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000001108 239.0
DTH1_k127_624697_3 Competence-damaged protein K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000002482 168.0
DTH1_k127_624697_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002793 141.0
DTH1_k127_624697_5 Belongs to the 'phage' integrase family - - - 0.000000000000000001002 86.0
DTH1_k127_6254255_0 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003915 256.0
DTH1_k127_6254255_1 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000009926 126.0
DTH1_k127_6287288_0 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000001248 168.0
DTH1_k127_6305022_0 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 357.0
DTH1_k127_6305022_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000001284 174.0
DTH1_k127_6305022_2 FAD dependent oxidoreductase K07007 - - 0.00000000000000000000000000000000001064 137.0
DTH1_k127_6321745_0 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000003299 237.0
DTH1_k127_6321745_1 Dihydroxyacetone kinase family - - - 0.000000000000000000000000000000001559 137.0
DTH1_k127_6323981_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 325.0
DTH1_k127_6323981_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 319.0
DTH1_k127_6326882_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 412.0
DTH1_k127_6326882_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000001261 156.0
DTH1_k127_6326882_2 Belongs to the CinA family K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000001378 73.0
DTH1_k127_6336337_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 485.0
DTH1_k127_6336337_1 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000105 77.0
DTH1_k127_6336337_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000005079 76.0
DTH1_k127_6336337_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000003068 51.0
DTH1_k127_6343594_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 301.0
DTH1_k127_6343594_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000915 113.0
DTH1_k127_6352342_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 465.0
DTH1_k127_6352342_1 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000006632 141.0
DTH1_k127_6355380_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 516.0
DTH1_k127_6355380_1 Protein of unknown function (DUF1464) - - - 0.00000000002586 66.0
DTH1_k127_6381490_0 III protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 374.0
DTH1_k127_6381490_1 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000001285 121.0
DTH1_k127_6382782_0 Major facilitator superfamily K03449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 393.0
DTH1_k127_6382782_1 Acetyl xylan esterase (AXE1) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 312.0
DTH1_k127_6382782_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000001341 199.0
DTH1_k127_6382782_3 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000001919 111.0
DTH1_k127_6382782_4 Glyoxalase-like domain K05606 - 5.1.99.1 0.0009014 46.0
DTH1_k127_6410000_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000001963 182.0
DTH1_k127_6410000_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000005988 102.0
DTH1_k127_6411612_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 354.0
DTH1_k127_6411612_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000003166 153.0
DTH1_k127_6411612_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000003014 128.0
DTH1_k127_6411612_3 4Fe-4S dicluster domain - - - 0.00000000000000000001912 93.0
DTH1_k127_6413298_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 408.0
DTH1_k127_6413298_1 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.0000000000008578 71.0
DTH1_k127_6432270_0 E1-E2 ATPase K01531 - 3.6.3.2 2.772e-226 730.0
DTH1_k127_6437090_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.0000000000000000000000000000000000000000000000000000000002374 218.0
DTH1_k127_644243_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 422.0
DTH1_k127_644243_1 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000005053 102.0
DTH1_k127_6443540_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 427.0
DTH1_k127_6454435_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000002576 226.0
DTH1_k127_6454435_1 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000001169 204.0
DTH1_k127_6462858_0 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003481 259.0
DTH1_k127_6462858_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000004018 251.0
DTH1_k127_6462858_2 COG COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000002358 132.0
DTH1_k127_6462858_3 peptidase, M24 - - - 0.000000000000001984 80.0
DTH1_k127_6477130_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 387.0
DTH1_k127_6477130_1 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.00000000000000000000000000000000000000000005498 165.0
DTH1_k127_6478891_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
DTH1_k127_6482084_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 4.973e-214 673.0
DTH1_k127_6482084_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 500.0
DTH1_k127_6482084_2 - - - - 0.0000000000000000000000006505 111.0
DTH1_k127_6482084_3 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000001516 68.0
DTH1_k127_6486536_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.666e-247 775.0
DTH1_k127_6486536_1 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 569.0
DTH1_k127_6486536_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000001032 159.0
DTH1_k127_6486536_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000004806 127.0
DTH1_k127_6487243_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 539.0
DTH1_k127_6487243_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000001669 179.0
DTH1_k127_6489293_0 Elongation factor G C-terminus K06207 - - 2.517e-265 830.0
DTH1_k127_6489293_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 304.0
DTH1_k127_6512699_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 331.0
DTH1_k127_6512699_1 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000295 181.0
DTH1_k127_6512699_2 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000001802 123.0
DTH1_k127_6512699_3 Methyltransferase type 11 - - - 0.00000000000000009208 88.0
DTH1_k127_6512699_4 - - - - 0.000000001171 66.0
DTH1_k127_6512699_5 methyltransferase K16648 - - 0.0008605 49.0
DTH1_k127_6513801_0 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000006841 153.0
DTH1_k127_6522319_0 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000002017 212.0
DTH1_k127_6522319_1 YHYH protein - - - 0.00000000000000002251 92.0
DTH1_k127_6522319_2 Flavodoxin domain - - - 0.0000006764 55.0
DTH1_k127_6526207_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 505.0
DTH1_k127_6526207_1 Transcriptional regulator - - - 0.0000000000000000000000000000000007301 133.0
DTH1_k127_6526572_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002033 253.0
DTH1_k127_6526572_1 PFAM MaoC like domain - - - 0.0000000000000000000000000005238 119.0
DTH1_k127_6526572_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.00001102 49.0
DTH1_k127_6547167_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000001399 223.0
DTH1_k127_6547167_1 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000003237 179.0
DTH1_k127_6547167_2 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000003459 74.0
DTH1_k127_6558701_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
DTH1_k127_656291_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 9.278e-265 835.0
DTH1_k127_656291_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 290.0
DTH1_k127_656291_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000000000000000000000000000000000001343 174.0
DTH1_k127_656291_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000008345 135.0
DTH1_k127_656291_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000006147 106.0
DTH1_k127_656291_5 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000007349 106.0
DTH1_k127_6570399_0 Histidine kinase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001195 294.0
DTH1_k127_6570399_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000001403 170.0
DTH1_k127_6570399_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000536 81.0
DTH1_k127_6584264_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001982 226.0
DTH1_k127_6584264_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000001211 163.0
DTH1_k127_6589165_0 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000005215 244.0
DTH1_k127_6604956_0 Amidohydrolase K07045,K14333,K15063 - 4.1.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 408.0
DTH1_k127_6604956_1 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000001256 169.0
DTH1_k127_6604956_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0005731 50.0
DTH1_k127_6614611_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 458.0
DTH1_k127_6614611_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 301.0
DTH1_k127_6614611_2 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 275.0
DTH1_k127_6614611_3 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000007768 169.0
DTH1_k127_6614611_4 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000002464 123.0
DTH1_k127_6616332_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 505.0
DTH1_k127_666522_0 Iron dependent K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000005831 229.0
DTH1_k127_666522_1 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000000000005055 217.0
DTH1_k127_6687281_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 494.0
DTH1_k127_6687281_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 375.0
DTH1_k127_6687281_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001685 235.0
DTH1_k127_6711217_0 AMP-binding enzyme K01897 - 6.2.1.3 4.58e-223 698.0
DTH1_k127_6711217_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 469.0
DTH1_k127_6711217_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 467.0
DTH1_k127_6711217_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 376.0
DTH1_k127_6723900_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000025 165.0
DTH1_k127_6723900_1 alpha-L-arabinofuranosidase - - - 0.000000000003694 73.0
DTH1_k127_6761146_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 339.0
DTH1_k127_6761146_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000001044 241.0
DTH1_k127_6765201_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 326.0
DTH1_k127_6765201_1 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000271 157.0
DTH1_k127_6765201_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000009591 118.0
DTH1_k127_6765201_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000002091 85.0
DTH1_k127_677494_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 507.0
DTH1_k127_677494_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000004601 247.0
DTH1_k127_677494_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000006123 233.0
DTH1_k127_677494_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000006109 196.0
DTH1_k127_677494_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000001367 178.0
DTH1_k127_677494_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000006071 151.0
DTH1_k127_678115_0 PFAM RNA binding S1 domain protein K02945 - - 0.0000000000000000000000000000000000000000000000000000887 198.0
DTH1_k127_6788472_0 GXGXG motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 400.0
DTH1_k127_6788472_1 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 396.0
DTH1_k127_6792066_0 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 423.0
DTH1_k127_6792066_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.0000002 52.0
DTH1_k127_6802395_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001744 281.0
DTH1_k127_6811347_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 537.0
DTH1_k127_6811347_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
DTH1_k127_6811347_2 PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000003231 172.0
DTH1_k127_6811347_3 AAA domain K07028 - - 0.0000000000002703 78.0
DTH1_k127_6813222_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 392.0
DTH1_k127_6813222_1 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000009861 91.0
DTH1_k127_6827546_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 7.962e-245 767.0
DTH1_k127_6827546_1 HMGL-like K02594 - 2.3.3.14 3.158e-198 625.0
DTH1_k127_6827546_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 505.0
DTH1_k127_6827546_3 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677,K03779 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 336.0
DTH1_k127_6827546_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 335.0
DTH1_k127_6827546_5 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000203 288.0
DTH1_k127_6827546_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000002486 203.0
DTH1_k127_6827546_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000009326 71.0
DTH1_k127_6827546_8 succinate dehydrogenase activity K00242,K00246 - - 0.000001405 55.0
DTH1_k127_686426_0 Hep Hag repeat protein - - - 0.00000000000000008476 95.0
DTH1_k127_6866172_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 404.0
DTH1_k127_6870785_0 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000001111 220.0
DTH1_k127_6870785_1 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.000000000000000000000001609 121.0
DTH1_k127_6870785_2 YHYH protein - - - 0.00000000000000000977 93.0
DTH1_k127_6870785_3 Flavin containing amine oxidoreductase - - - 0.0006339 46.0
DTH1_k127_6871267_0 Hydrolase - - - 0.00000000009922 72.0
DTH1_k127_6879088_0 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000001956 158.0
DTH1_k127_6887519_0 Telomere recombination K04656 - - 1.516e-269 850.0
DTH1_k127_6887519_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 408.0
DTH1_k127_6887519_2 PFAM DegV family protein - - - 0.0000000000000000000000003388 109.0
DTH1_k127_6887519_3 hydrogenase assembly chaperone HypC HupF K04653 - - 0.000000000000000004345 85.0
DTH1_k127_6889611_0 - - - - 0.0005426 49.0
DTH1_k127_6897814_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000009556 183.0
DTH1_k127_6900725_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 571.0
DTH1_k127_6900725_1 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000006435 174.0
DTH1_k127_6900725_2 - - - - 0.0000000000000000000000433 107.0
DTH1_k127_6900725_3 Protein of unknown function (DUF1847) - - - 0.00000000000000001986 83.0
DTH1_k127_6946338_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 1.132e-200 649.0
DTH1_k127_6946338_1 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000001384 225.0
DTH1_k127_6946338_2 Transcription factor zinc-finger K09981 - - 0.000000000004456 70.0
DTH1_k127_6954870_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000003532 109.0
DTH1_k127_6954870_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000006075 69.0
DTH1_k127_6963420_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 241.0
DTH1_k127_6963420_1 Thioredoxin - - - 0.000000000000000000009884 100.0
DTH1_k127_6991034_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 620.0
DTH1_k127_7005270_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000604 91.0
DTH1_k127_7005270_1 metallopeptidase activity K01186 - 3.2.1.18 0.0000000000000000127 97.0
DTH1_k127_7010853_0 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 303.0
DTH1_k127_7010853_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000001483 199.0
DTH1_k127_7051484_0 Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 303.0
DTH1_k127_7051484_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000006985 139.0
DTH1_k127_7081312_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 414.0
DTH1_k127_7081312_1 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 279.0
DTH1_k127_7081312_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000003103 85.0
DTH1_k127_7102491_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000006351 205.0
DTH1_k127_7102491_1 Oxidoreductase K15022 - 1.17.1.10 0.000000000000000000000000000000005251 133.0
DTH1_k127_7102491_2 Histidine kinase K07777 - 2.7.13.3 0.000000000000000000000000001205 119.0
DTH1_k127_7121867_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003613 233.0
DTH1_k127_7148062_0 Poly A polymerase head domain K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 301.0
DTH1_k127_7148062_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000001111 211.0
DTH1_k127_7148062_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000005544 183.0
DTH1_k127_7245699_0 ATPase AAA-2 domain protein K03696 - - 0.0 1053.0
DTH1_k127_7245699_1 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000001096 68.0
DTH1_k127_7267040_0 R3H domain - - - 1.926e-203 646.0
DTH1_k127_7267040_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 469.0
DTH1_k127_7267040_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000001074 187.0
DTH1_k127_7267040_3 Alpha/beta hydrolase family - - - 0.0000000001164 64.0
DTH1_k127_7321568_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005651 244.0
DTH1_k127_7324711_0 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 534.0
DTH1_k127_7324711_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 363.0
DTH1_k127_7324711_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000001279 164.0
DTH1_k127_7324711_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000001363 138.0
DTH1_k127_7324711_4 COG0170 Dolichol kinase - - - 0.00005146 53.0
DTH1_k127_7362305_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 464.0
DTH1_k127_7362305_1 - - - - 0.0000008862 55.0
DTH1_k127_7397428_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000002962 246.0
DTH1_k127_7397428_1 PFAM ABC-2 type transporter K01992 - - 0.000009003 53.0
DTH1_k127_7399342_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1068.0
DTH1_k127_7399342_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004095 273.0
DTH1_k127_7399342_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
DTH1_k127_7452298_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000003623 178.0
DTH1_k127_7452298_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000007034 162.0
DTH1_k127_7452298_2 DHH family K07462 - - 0.00000000000000000000000000000002152 129.0
DTH1_k127_7452298_3 Putative Fe-S cluster - - - 0.00000000000000000000211 100.0
DTH1_k127_7453354_0 FAD binding domain - - - 0.0000000005894 70.0
DTH1_k127_7470557_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 338.0
DTH1_k127_7470557_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000003554 65.0
DTH1_k127_747961_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000005606 168.0
DTH1_k127_749187_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 7.188e-260 816.0
DTH1_k127_749187_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000001721 214.0
DTH1_k127_7502940_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 8.612e-216 682.0
DTH1_k127_7506123_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 571.0
DTH1_k127_7506123_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000005827 171.0
DTH1_k127_7506123_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000047 123.0
DTH1_k127_7506123_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000004669 83.0
DTH1_k127_7506123_4 membrane protein (DUF2078) K08982 - - 0.000000002863 61.0
DTH1_k127_7516925_0 electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000007981 206.0
DTH1_k127_752172_0 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000273 153.0
DTH1_k127_7532023_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 561.0
DTH1_k127_7536034_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 301.0
DTH1_k127_7536034_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002388 285.0
DTH1_k127_7545227_0 PFAM 4Fe-4S binding domain K00184 - - 0.00000000000000000000000000000002257 129.0
DTH1_k127_7545227_1 Formate-dependent nitrite reductase, membrane - - - 0.0000000000000000002042 96.0
DTH1_k127_7557951_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 9.815e-302 931.0
DTH1_k127_7557951_1 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000002262 55.0
DTH1_k127_7576488_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 507.0
DTH1_k127_7576488_1 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 340.0
DTH1_k127_7576488_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 304.0
DTH1_k127_7576488_3 Helix-turn-helix domain - - - 0.00000000000000000001955 99.0
DTH1_k127_7581971_0 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002932 282.0
DTH1_k127_7608973_0 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005788 278.0
DTH1_k127_7608973_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000005305 194.0
DTH1_k127_7608973_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000007244 189.0
DTH1_k127_7608973_3 GAF domain - - - 0.00000000000000000000000000000000000000000000001265 186.0
DTH1_k127_7608973_4 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000001301 126.0
DTH1_k127_7625311_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000003034 192.0
DTH1_k127_7625311_1 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000007331 151.0
DTH1_k127_7625311_2 Transposase - - - 0.00000000000000000000000000000000001327 137.0
DTH1_k127_7625311_3 PFAM Integrase catalytic region K07497 - - 0.0000000001744 63.0
DTH1_k127_762975_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 451.0
DTH1_k127_762975_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 301.0
DTH1_k127_762975_2 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.0000000000000000000000000000000000000000000000000000000009347 213.0
DTH1_k127_762975_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000004023 204.0
DTH1_k127_762975_4 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000763 130.0
DTH1_k127_7678401_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 576.0
DTH1_k127_7678401_1 Elongation factor Tu domain 2 K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 589.0
DTH1_k127_7678401_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 301.0
DTH1_k127_7678401_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000009367 244.0
DTH1_k127_7678401_4 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000003459 160.0
DTH1_k127_7678401_5 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000001837 123.0
DTH1_k127_7718663_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 355.0
DTH1_k127_7718663_1 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000001407 60.0
DTH1_k127_7751748_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 548.0
DTH1_k127_7764899_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 479.0
DTH1_k127_7764899_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000004262 149.0
DTH1_k127_7764899_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000003429 65.0
DTH1_k127_7776557_0 DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000003457 238.0
DTH1_k127_7776557_1 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000000000000000000001951 159.0
DTH1_k127_7776557_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000167 147.0
DTH1_k127_7776557_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000004234 136.0
DTH1_k127_7776557_4 - - - - 0.0000000000000000000000000002946 116.0
DTH1_k127_7786346_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 391.0
DTH1_k127_7786346_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000001905 162.0
DTH1_k127_7786346_2 SNARE associated Golgi protein - - - 0.0000000000000005323 79.0
DTH1_k127_7800954_0 domain protein - - - 0.0000000000001348 83.0
DTH1_k127_7805275_0 Heat shock 70 kDa protein K04043 - - 5.543e-287 891.0
DTH1_k127_7805275_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002703 254.0
DTH1_k127_7807888_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 403.0
DTH1_k127_7807888_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000001699 223.0
DTH1_k127_7807888_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000001218 61.0
DTH1_k127_7886821_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000003969 258.0
DTH1_k127_7886821_1 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000596 211.0
DTH1_k127_7901368_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 348.0
DTH1_k127_7901368_1 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 350.0
DTH1_k127_7901368_2 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 294.0
DTH1_k127_7901368_3 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000002635 199.0
DTH1_k127_7901368_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000838 156.0
DTH1_k127_7901368_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000252 122.0
DTH1_k127_7901368_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000001916 113.0
DTH1_k127_7901368_7 Binds the 23S rRNA K02909 - - 0.00000000000000000000000002086 109.0
DTH1_k127_7966167_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 534.0
DTH1_k127_7966167_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000003655 141.0
DTH1_k127_798322_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 559.0
DTH1_k127_798322_1 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 382.0
DTH1_k127_798322_2 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 287.0
DTH1_k127_798322_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.00000000000000000000001687 106.0
DTH1_k127_7989393_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000005293 190.0
DTH1_k127_7989393_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000015 184.0
DTH1_k127_7997994_0 FAD dependent oxidoreductase K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
DTH1_k127_8000203_0 Pyruvate formate lyase-like K07540 - 4.1.99.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 536.0
DTH1_k127_8000203_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 424.0
DTH1_k127_8000203_2 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000009574 200.0
DTH1_k127_8000203_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.0000002634 53.0
DTH1_k127_8006021_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 312.0
DTH1_k127_8006021_1 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000001523 100.0
DTH1_k127_8015325_0 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000004782 243.0
DTH1_k127_8015325_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000001252 69.0
DTH1_k127_801864_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 300.0
DTH1_k127_801864_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000305 269.0
DTH1_k127_801864_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006915 246.0
DTH1_k127_801864_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000006404 112.0
DTH1_k127_801864_4 ATP binding cassette transporter ABC protein K01990 - - 0.0005003 45.0
DTH1_k127_8034919_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 407.0
DTH1_k127_8034919_1 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000001004 169.0
DTH1_k127_8034919_2 helix_turn_helix ASNC type K03718 - - 0.0000000000000002949 84.0
DTH1_k127_8048034_0 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000001407 93.0
DTH1_k127_8048034_1 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000008947 85.0
DTH1_k127_8062990_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 466.0
DTH1_k127_8073440_0 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
DTH1_k127_8073440_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008592 229.0
DTH1_k127_8083435_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 377.0
DTH1_k127_8083435_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 270.0
DTH1_k127_8083435_2 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.000000000002391 71.0
DTH1_k127_8088746_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 507.0
DTH1_k127_8088746_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 497.0
DTH1_k127_8088746_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000006599 146.0
DTH1_k127_8094191_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 491.0
DTH1_k127_8094191_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 417.0
DTH1_k127_8094191_2 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000002209 186.0
DTH1_k127_8094191_3 ligase activity, forming carbon-carbon bonds K07402 - - 0.000000000000000005787 86.0
DTH1_k127_811873_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 332.0
DTH1_k127_811873_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000001944 90.0
DTH1_k127_8118952_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 328.0
DTH1_k127_8118952_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000004808 139.0
DTH1_k127_8121171_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.011e-317 988.0
DTH1_k127_8121171_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000436 241.0
DTH1_k127_8121171_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000002164 227.0
DTH1_k127_8121171_3 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000003497 51.0
DTH1_k127_8140397_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 556.0
DTH1_k127_8140397_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 454.0
DTH1_k127_8143334_0 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000004172 136.0
DTH1_k127_8143334_1 TIGRFAM Tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000005754 120.0
DTH1_k127_8155757_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000002697 228.0
DTH1_k127_8177655_0 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000004556 182.0
DTH1_k127_8177655_1 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000001256 150.0
DTH1_k127_8177655_2 PFAM Uncharacterised ACR, YkgG family COG1556 K00782 - - 0.00000005841 56.0
DTH1_k127_8179399_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.446e-305 955.0
DTH1_k127_8179399_1 Dak1_2 K07030 - - 1.226e-203 647.0
DTH1_k127_8179399_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001319 265.0
DTH1_k127_8179399_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000005592 228.0
DTH1_k127_8179399_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000002296 118.0
DTH1_k127_8179399_5 PFAM response regulator receiver - - - 0.0000000000000000000002441 101.0
DTH1_k127_8179399_6 Ribosomal L28 family K02902 - - 0.0000000000000000002228 90.0
DTH1_k127_8179399_7 CRP FNR family transcriptional regulator K01420 - - 0.00002472 53.0
DTH1_k127_8181584_1 - K01278,K03561,K12287 - 3.4.14.5 0.0000000000000000009418 97.0
DTH1_k127_8196294_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 361.0
DTH1_k127_8196547_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 437.0
DTH1_k127_8196916_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 320.0
DTH1_k127_8196916_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 308.0
DTH1_k127_8196916_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000001253 99.0
DTH1_k127_8196916_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000372 50.0
DTH1_k127_8261596_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000006378 198.0
DTH1_k127_8261596_1 - - - - 0.00000000000001421 74.0
DTH1_k127_8268969_0 DNA modification repair radical SAM protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 329.0
DTH1_k127_8277209_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001148 284.0
DTH1_k127_8277209_1 Zincin-like metallopeptidase - - - 0.00000000000000000000003122 103.0
DTH1_k127_8328444_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.086e-291 914.0
DTH1_k127_8336681_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.498e-224 711.0
DTH1_k127_8336681_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 527.0
DTH1_k127_8336681_2 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 383.0
DTH1_k127_8336681_3 PQ loop repeat K15383 - - 0.0000003975 53.0
DTH1_k127_8403680_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 569.0
DTH1_k127_8403680_1 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
DTH1_k127_8403680_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000008124 243.0
DTH1_k127_8403680_3 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.0000000000000000000000000000000000000001424 155.0
DTH1_k127_8422666_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 533.0
DTH1_k127_8422666_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 405.0
DTH1_k127_8422666_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001958 271.0
DTH1_k127_8422666_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000007842 224.0
DTH1_k127_8472748_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001053 291.0
DTH1_k127_8472748_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000003742 145.0
DTH1_k127_8474944_0 ABC transporter, transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 559.0
DTH1_k127_8474944_1 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 357.0
DTH1_k127_8474944_2 PFAM LmbE family protein K18455 - 3.5.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 302.0
DTH1_k127_8474944_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000377 173.0
DTH1_k127_8474944_4 Protein of unknown function (DUF664) - - - 0.00000000000003212 79.0
DTH1_k127_8477069_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002598 250.0
DTH1_k127_8477069_1 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000000002051 194.0
DTH1_k127_8477069_2 Cytochrome c3 - - - 0.00000000000000000000000002479 116.0
DTH1_k127_8481054_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000006832 186.0
DTH1_k127_8481054_1 Histidine kinase-like ATPases K04079 - - 0.0000000234 66.0
DTH1_k127_8484230_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 373.0
DTH1_k127_8484230_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 299.0
DTH1_k127_8484230_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000458 168.0
DTH1_k127_8484230_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000003889 99.0
DTH1_k127_8488982_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1164.0
DTH1_k127_8488982_1 - - - - 0.00004621 50.0
DTH1_k127_8488982_2 Recombinase zinc beta ribbon domain - - - 0.0002688 44.0
DTH1_k127_850325_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 306.0
DTH1_k127_850325_1 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008968 287.0
DTH1_k127_850325_2 transport system involved in gliding motility, auxiliary K01992 - - 0.0000000000000000000000000000000000000000000000000000000002853 222.0
DTH1_k127_850325_3 Psort location CytoplasmicMembrane, score K01992 - - 0.000000000000000000000000000000000000000000000001133 183.0
DTH1_k127_850325_4 Domain of unknown function (DUF4340) - - - 0.000000001184 66.0
DTH1_k127_8523969_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 595.0
DTH1_k127_8523969_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003095 274.0
DTH1_k127_8523969_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000006567 236.0
DTH1_k127_8523969_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000007041 204.0
DTH1_k127_8523969_4 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000009615 153.0
DTH1_k127_8523969_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000002473 127.0
DTH1_k127_8523969_6 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000004616 83.0
DTH1_k127_8533847_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000001556 213.0
DTH1_k127_8542893_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 576.0
DTH1_k127_8542893_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003248 264.0
DTH1_k127_8542893_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000002683 201.0
DTH1_k127_8542893_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000007285 133.0
DTH1_k127_8545080_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.157e-227 722.0
DTH1_k127_8545080_1 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000135 205.0
DTH1_k127_8545080_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000001168 152.0
DTH1_k127_8545080_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000007125 117.0
DTH1_k127_8552137_0 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 365.0
DTH1_k127_8552137_1 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000000000000006904 230.0
DTH1_k127_8552137_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000006148 202.0
DTH1_k127_8552137_3 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000181 201.0
DTH1_k127_8552137_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000002119 136.0
DTH1_k127_8552137_5 Colicin V production protein K03558 - - 0.0000000000000000000000000000000005434 137.0
DTH1_k127_8552137_6 - - - - 0.000000000000000000008059 102.0
DTH1_k127_8558938_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 388.0
DTH1_k127_8558938_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003556 257.0
DTH1_k127_8558938_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000001802 108.0
DTH1_k127_8565341_0 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000002889 241.0
DTH1_k127_8565341_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000009064 188.0
DTH1_k127_8588163_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 574.0
DTH1_k127_8588163_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 281.0
DTH1_k127_8588163_2 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000953 249.0
DTH1_k127_8588163_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000007701 209.0
DTH1_k127_8588163_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000002461 153.0
DTH1_k127_8593643_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K07469,K11177 - 1.17.1.4,1.2.5.3,1.2.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 479.0
DTH1_k127_8593643_1 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000007318 94.0
DTH1_k127_8595953_0 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 355.0
DTH1_k127_8595953_1 Protein of unknown function (DUF1847) - - - 0.000000000004321 70.0
DTH1_k127_8612264_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 427.0
DTH1_k127_8612264_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000001066 68.0
DTH1_k127_8653946_0 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 297.0
DTH1_k127_8653946_1 Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002163 261.0
DTH1_k127_8680475_0 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 307.0
DTH1_k127_8680475_1 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 289.0
DTH1_k127_8680475_2 - - - - 0.0000000000000000000000000000000000000000000000000003872 192.0
DTH1_k127_8680475_3 PAC2 family - - - 0.000000000000000000000000000000000000000009206 165.0
DTH1_k127_8796158_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000004426 186.0
DTH1_k127_8796158_1 - K07403 - - 0.0000009166 57.0
DTH1_k127_8798930_0 Subtilase family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000001406 199.0
DTH1_k127_8802914_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 488.0
DTH1_k127_8802914_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003033 282.0
DTH1_k127_8802914_2 Glutamine amidotransferase class-I - - - 0.0000000000000000000000001985 110.0
DTH1_k127_8802914_3 CTP synthase K01937 - 6.3.4.2 0.000000000000742 72.0
DTH1_k127_8817145_0 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 488.0
DTH1_k127_8817145_1 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 417.0
DTH1_k127_8817145_2 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000177 183.0
DTH1_k127_8817878_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 587.0
DTH1_k127_8817878_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001189 235.0
DTH1_k127_8817878_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
DTH1_k127_8817878_3 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000002274 182.0
DTH1_k127_8817878_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000007736 166.0
DTH1_k127_8817878_5 RNase_H superfamily K07502 - - 0.000000001617 61.0
DTH1_k127_8817878_6 RNase_H superfamily K07502 - - 0.0000002265 54.0
DTH1_k127_8822428_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 582.0
DTH1_k127_8822428_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 569.0
DTH1_k127_8881916_0 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 386.0
DTH1_k127_8881916_1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000003904 182.0
DTH1_k127_8881916_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000137 131.0
DTH1_k127_8912012_0 Fumarate reductase flavoprotein C-term - - - 0.000000000000000000000533 108.0
DTH1_k127_8912644_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 482.0
DTH1_k127_8912644_1 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003695 273.0
DTH1_k127_8912644_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000188 163.0
DTH1_k127_8912644_3 ABC-2 family transporter protein - - - 0.00000000000000000000001004 109.0
DTH1_k127_8942365_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 299.0
DTH1_k127_8942365_1 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000005054 189.0
DTH1_k127_8942365_2 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.0000000000000000000000000000000000005045 143.0
DTH1_k127_8942365_3 cell redox homeostasis - - - 0.000000000000000000001168 97.0
DTH1_k127_9002447_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 368.0
DTH1_k127_9038043_0 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000001021 210.0
DTH1_k127_9038043_1 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000003489 187.0
DTH1_k127_9046985_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 431.0
DTH1_k127_9046985_1 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 364.0
DTH1_k127_9046985_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000001262 115.0
DTH1_k127_9062521_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.789e-262 817.0
DTH1_k127_9062521_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.03e-212 666.0
DTH1_k127_9062521_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 8.299e-199 631.0
DTH1_k127_9062521_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 304.0
DTH1_k127_9087029_0 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 298.0
DTH1_k127_9087029_1 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006164 244.0
DTH1_k127_9087029_2 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000001638 139.0
DTH1_k127_9087029_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000003805 126.0
DTH1_k127_9087029_4 - - - - 0.000000000000000001078 85.0
DTH1_k127_9118659_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003984 284.0
DTH1_k127_9118659_1 nucleic-acid-binding protein containing a Zn-ribbon - - - 0.0000000000000000000006735 99.0
DTH1_k127_9143001_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 431.0
DTH1_k127_9143001_1 2-methylcitrate dehydratase activity K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000003118 189.0
DTH1_k127_9158433_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000002367 148.0
DTH1_k127_9158433_1 META domain protein - - - 0.0000000000003813 75.0
DTH1_k127_9207453_0 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001339 266.0
DTH1_k127_9207453_1 Putative regulatory protein - - - 0.0000000000000001753 83.0
DTH1_k127_9207453_2 - - - - 0.0000000000108 65.0
DTH1_k127_9215836_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000006689 215.0
DTH1_k127_9249441_0 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 437.0
DTH1_k127_9249441_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
DTH1_k127_9249441_2 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000002307 173.0
DTH1_k127_9249441_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000001117 131.0
DTH1_k127_9249441_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000001731 111.0
DTH1_k127_9249441_5 Parallel beta-helix repeats - - - 0.0002845 44.0
DTH1_k127_9274608_0 MFS_1 like family - - - 0.000000000000000000000000000000000000000000704 173.0
DTH1_k127_9295836_0 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002246 266.0
DTH1_k127_9295836_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
DTH1_k127_9295836_2 KH domain K06346 - - 0.00000000000000000000000000000000000000000000000000008725 194.0
DTH1_k127_9295836_3 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000001366 159.0
DTH1_k127_9295836_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000002796 121.0
DTH1_k127_9295836_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000679 108.0
DTH1_k127_9295836_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000007525 85.0
DTH1_k127_9295836_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000002727 76.0
DTH1_k127_9296314_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.000000000000000000000000000000000001017 145.0
DTH1_k127_9305260_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 366.0
DTH1_k127_9306928_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
DTH1_k127_9306928_1 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000006845 203.0
DTH1_k127_9306928_2 PFAM molybdopterin-guanine dinucleotide biosynthesis MobB region K03753 - - 0.0001415 48.0
DTH1_k127_9306928_3 - - - - 0.0005841 49.0
DTH1_k127_9308674_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 291.0
DTH1_k127_9308674_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000001295 235.0
DTH1_k127_9308674_2 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000002829 135.0
DTH1_k127_9308674_3 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.000000000000000000000000000001505 123.0
DTH1_k127_9308674_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000004431 70.0
DTH1_k127_9325874_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 361.0
DTH1_k127_9325874_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000002553 185.0
DTH1_k127_9325874_2 structural constituent of ribosome K02879 - - 0.0000000000000000000000000000000000000000001522 162.0
DTH1_k127_9325874_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004507 153.0
DTH1_k127_9325874_4 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000006125 60.0
DTH1_k127_9358381_0 PFAM Response regulator receiver domain K02479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
DTH1_k127_9358381_1 Histidine kinase - - - 0.0000003906 55.0
DTH1_k127_9389780_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 400.0
DTH1_k127_9389780_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 396.0
DTH1_k127_9389780_2 acid phosphatase activity - - - 0.0000000000000000001425 97.0
DTH1_k127_9389832_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 582.0
DTH1_k127_9389832_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 397.0
DTH1_k127_9409285_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000001737 162.0
DTH1_k127_9409285_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000003697 68.0
DTH1_k127_9411525_0 Resolvase, N terminal domain - - - 5.894e-198 625.0
DTH1_k127_9430885_0 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000009425 238.0
DTH1_k127_9430885_1 - - - - 0.0000000000000008523 82.0
DTH1_k127_9445404_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.196e-219 691.0
DTH1_k127_9445404_1 Alpha/beta hydrolase family K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000672 213.0
DTH1_k127_9489293_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 506.0
DTH1_k127_9498937_0 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000152 277.0
DTH1_k127_9498937_1 cell redox homeostasis K00384,K03671 - 1.8.1.9 0.00000000000000000000009624 105.0
DTH1_k127_9518737_0 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 0.00000000000000000000000000000000001238 145.0
DTH1_k127_9518737_1 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000002114 130.0
DTH1_k127_9532068_0 Thymidylate synthase K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 332.0
DTH1_k127_9532068_1 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 289.0
DTH1_k127_9532068_2 - - - - 0.0000000007581 60.0
DTH1_k127_9534053_0 NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 369.0
DTH1_k127_9534053_1 hmm pf01266 K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000001638 241.0
DTH1_k127_9534053_2 MmgE/PrpD family - - - 0.00000000000000000000000007623 122.0
DTH1_k127_9534053_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000003511 60.0
DTH1_k127_9534053_4 Radical SAM domain protein - - - 0.0000000114 56.0
DTH1_k127_9534053_5 mttA/Hcf106 family K03116 - - 0.00000002003 61.0
DTH1_k127_9594203_0 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000001299 156.0
DTH1_k127_9594203_1 transcriptional regulator PadR family K10947 - - 0.000000000000000000000001805 108.0
DTH1_k127_960165_0 TIGRFAM sodium ion-translocating decarboxylase, beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 311.0
DTH1_k127_960165_1 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000001545 231.0
DTH1_k127_960165_2 Cytidylate kinase-like family - - - 0.0000000000000000008825 94.0
DTH1_k127_9605967_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 9.448e-246 769.0
DTH1_k127_9605967_1 Ftsk_gamma K03466 - - 1.146e-233 744.0
DTH1_k127_9605967_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 516.0
DTH1_k127_9605967_3 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000006756 242.0
DTH1_k127_9605967_4 Cupin domain - - - 0.0000000000000000000000000000000000197 138.0
DTH1_k127_9609261_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 312.0
DTH1_k127_9609261_1 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008803 262.0
DTH1_k127_9609476_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 361.0
DTH1_k127_964653_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 336.0
DTH1_k127_9658443_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 552.0
DTH1_k127_9658443_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 439.0
DTH1_k127_9658443_2 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 448.0
DTH1_k127_9658443_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 404.0
DTH1_k127_9658443_4 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 293.0
DTH1_k127_9658443_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001553 257.0
DTH1_k127_9658443_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000008007 172.0
DTH1_k127_9668500_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1178.0
DTH1_k127_9668500_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 488.0
DTH1_k127_9668500_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000003043 245.0
DTH1_k127_9668500_3 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000003589 101.0
DTH1_k127_9684483_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 332.0
DTH1_k127_9684483_1 Family of unknown function (DUF438) K09155 - - 0.00000000000000000000000000000001447 132.0
DTH1_k127_9691837_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 301.0
DTH1_k127_9691837_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000004591 61.0
DTH1_k127_9691837_2 PFAM Cupin - - - 0.0002695 49.0
DTH1_k127_9729282_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 386.0
DTH1_k127_9729282_1 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000001409 141.0
DTH1_k127_973348_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 4.475e-285 888.0
DTH1_k127_973348_1 calcium proton exchanger K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003764 265.0
DTH1_k127_9739549_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 555.0
DTH1_k127_9739549_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000434 224.0
DTH1_k127_9739549_2 - - - - 0.0000000000000000000000000000000000000000000001217 177.0
DTH1_k127_9739549_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000002309 96.0
DTH1_k127_9753395_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 448.0
DTH1_k127_9753395_1 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000385 286.0
DTH1_k127_9753395_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000006336 86.0
DTH1_k127_9762334_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 341.0
DTH1_k127_9762334_1 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009858 243.0
DTH1_k127_9762334_2 - - - - 0.000000000000000000001007 95.0
DTH1_k127_9782724_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 308.0
DTH1_k127_9782724_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001232 284.0
DTH1_k127_978721_0 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.324e-207 658.0
DTH1_k127_978721_1 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 473.0
DTH1_k127_978721_2 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 298.0
DTH1_k127_978721_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000002318 144.0
DTH1_k127_9827085_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003617 263.0
DTH1_k127_9827085_1 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000002848 79.0
DTH1_k127_9922283_0 Alpha amylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 412.0
DTH1_k127_9922283_1 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000005029 208.0
DTH1_k127_9922283_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000005936 186.0