Overview

ID MAG00753
Name DTH1_bin.7
Sample SMP0022
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family UBA6910
Genus UBA6910
Species
Assembly information
Completeness (%) 82.5
Contamination (%) 3.93
GC content (%) 69.0
N50 (bp) 4,595
Genome size (bp) 2,612,090

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2770

Gene name Description KEGG GOs EC E-value Score Sequence
DTH1_k127_10000934_0 COG4618 ABC-type protease lipase transport system, ATPase and permease components K16299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 514.0
DTH1_k127_10000934_1 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 443.0
DTH1_k127_10000934_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000007289 147.0
DTH1_k127_10000934_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000001607 119.0
DTH1_k127_10000934_4 positive regulation of growth K07746 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.000000457 55.0
DTH1_k127_100143_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1560.0
DTH1_k127_100143_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 405.0
DTH1_k127_100143_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 381.0
DTH1_k127_100143_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000009837 187.0
DTH1_k127_100143_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003018 173.0
DTH1_k127_100143_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000958 164.0
DTH1_k127_100143_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000001434 132.0
DTH1_k127_100143_7 Peptidase family M23 - - - 0.00000000004158 72.0
DTH1_k127_10028516_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.982e-216 679.0
DTH1_k127_10028516_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 300.0
DTH1_k127_10030238_0 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 508.0
DTH1_k127_10030238_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009957 263.0
DTH1_k127_10030238_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000002032 219.0
DTH1_k127_10030238_3 Bacterial SH3 domain - - - 0.000000000000000000001357 110.0
DTH1_k127_10031195_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 447.0
DTH1_k127_10031195_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 319.0
DTH1_k127_10031195_2 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000003518 178.0
DTH1_k127_10032349_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1334.0
DTH1_k127_10032349_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 571.0
DTH1_k127_10032349_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 541.0
DTH1_k127_10032349_3 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000001655 86.0
DTH1_k127_10032349_4 Belongs to the ompA family K03286 - - 0.000000000000169 74.0
DTH1_k127_10033794_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 565.0
DTH1_k127_10033794_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 407.0
DTH1_k127_10033794_2 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 390.0
DTH1_k127_10033794_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000002368 249.0
DTH1_k127_10036845_0 MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 569.0
DTH1_k127_10095295_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 2.001e-268 832.0
DTH1_k127_10095295_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 585.0
DTH1_k127_10095295_10 Protein of unknown function (DUF504) - - - 0.00000000000000000003838 101.0
DTH1_k127_10095295_2 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 370.0
DTH1_k127_10095295_3 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 341.0
DTH1_k127_10095295_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 318.0
DTH1_k127_10095295_5 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
DTH1_k127_10095295_6 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000007576 234.0
DTH1_k127_10095295_7 maturation - - - 0.0000000000000000000000000000000000000000000009241 171.0
DTH1_k127_10095295_8 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000947 165.0
DTH1_k127_10095295_9 THUMP - - - 0.00000000000000000000000000001156 124.0
DTH1_k127_10104100_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000006366 212.0
DTH1_k127_10104100_1 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000001985 172.0
DTH1_k127_10104100_2 Belongs to the universal stress protein A family - - - 0.000000002332 64.0
DTH1_k127_10105379_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1067.0
DTH1_k127_10105379_1 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 302.0
DTH1_k127_10105379_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000001054 86.0
DTH1_k127_10105379_2 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003884 257.0
DTH1_k127_10105379_3 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000004183 182.0
DTH1_k127_10105379_4 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000004284 175.0
DTH1_k127_10105379_5 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000001109 143.0
DTH1_k127_10105379_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000000004627 139.0
DTH1_k127_10105379_7 CBS domain - - - 0.0000000000000000000000000000002324 134.0
DTH1_k127_10105379_8 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000000001849 126.0
DTH1_k127_10105379_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000005082 113.0
DTH1_k127_10107784_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 5.31e-229 716.0
DTH1_k127_10107784_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001356 245.0
DTH1_k127_10107784_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000007992 81.0
DTH1_k127_1012286_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.634e-261 816.0
DTH1_k127_1012286_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 393.0
DTH1_k127_1012286_3 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000004315 81.0
DTH1_k127_1012286_4 Subtilase family - - - 0.000000005534 65.0
DTH1_k127_1015242_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 598.0
DTH1_k127_1015242_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 462.0
DTH1_k127_1015242_2 Sodium/hydrogen exchanger family - - - 0.0006651 43.0
DTH1_k127_1019078_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 9.642e-274 854.0
DTH1_k127_1019078_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 604.0
DTH1_k127_1019078_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 422.0
DTH1_k127_1019078_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 390.0
DTH1_k127_1019078_4 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005259 285.0
DTH1_k127_1019078_5 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000006199 135.0
DTH1_k127_1019078_6 Thioredoxin K05838 - - 0.0000000000000000001908 89.0
DTH1_k127_1022810_0 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 357.0
DTH1_k127_1022810_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000009029 219.0
DTH1_k127_1022810_2 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000002701 211.0
DTH1_k127_1022810_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0001011 44.0
DTH1_k127_1031521_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 578.0
DTH1_k127_1031521_1 Cell division and transport-associated protein TolA K03646 - - 0.000000000000000000000000000000000002701 143.0
DTH1_k127_1045710_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 620.0
DTH1_k127_1045710_1 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 606.0
DTH1_k127_1045710_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 550.0
DTH1_k127_1045710_3 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 486.0
DTH1_k127_1045710_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 480.0
DTH1_k127_1045710_5 domain, Protein K15923 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 454.0
DTH1_k127_1045710_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 371.0
DTH1_k127_1045710_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 357.0
DTH1_k127_1045710_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000009936 96.0
DTH1_k127_1045710_9 response regulator - - - 0.0000000000000000001348 94.0
DTH1_k127_105054_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.369e-287 886.0
DTH1_k127_105054_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.195e-199 628.0
DTH1_k127_105054_2 Beta-Casp domain K07576 - - 2.423e-195 625.0
DTH1_k127_105054_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 573.0
DTH1_k127_105054_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 411.0
DTH1_k127_105054_5 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000000002818 202.0
DTH1_k127_105054_6 membrane - - - 0.0000000000000000000000000000000000000000008664 162.0
DTH1_k127_105054_7 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000003372 128.0
DTH1_k127_105054_8 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000005565 125.0
DTH1_k127_105054_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000135 75.0
DTH1_k127_1053431_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 6.359e-281 871.0
DTH1_k127_1053431_1 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 392.0
DTH1_k127_1053431_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 359.0
DTH1_k127_1067673_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001951 274.0
DTH1_k127_1067673_1 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001081 261.0
DTH1_k127_1070796_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.94e-270 844.0
DTH1_k127_1070796_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.411e-207 662.0
DTH1_k127_1070796_2 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000004994 199.0
DTH1_k127_1070796_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000004665 157.0
DTH1_k127_1070796_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000002113 124.0
DTH1_k127_1078001_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.197e-233 729.0
DTH1_k127_1078001_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 518.0
DTH1_k127_1078001_10 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0005623 44.0
DTH1_k127_1078001_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 401.0
DTH1_k127_1078001_3 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
DTH1_k127_1078001_4 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
DTH1_k127_1078001_5 ApaG domain - - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
DTH1_k127_1078001_6 PIN domain - - - 0.00000000000000000000000000000000000000000000009327 172.0
DTH1_k127_1078001_7 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000003339 155.0
DTH1_k127_1078001_8 positive regulation of growth K01081 - 3.1.3.5 0.00000000000000000000000001165 110.0
DTH1_k127_1078001_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000003144 114.0
DTH1_k127_1080715_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
DTH1_k127_1080715_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 407.0
DTH1_k127_1087893_0 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 427.0
DTH1_k127_1087893_1 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000003348 248.0
DTH1_k127_1102559_0 Heavy-metal-associated domain K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 428.0
DTH1_k127_1102559_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000002766 265.0
DTH1_k127_1102559_2 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
DTH1_k127_1102559_3 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001089 254.0
DTH1_k127_1102559_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
DTH1_k127_1110959_0 Membrane - - - 1.246e-284 881.0
DTH1_k127_1115076_0 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 288.0
DTH1_k127_1115076_1 Biotin-lipoyl like K02022 - - 0.000000000000003443 79.0
DTH1_k127_1115076_2 WD-40 repeat - - - 0.000000000000006895 89.0
DTH1_k127_1141402_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 457.0
DTH1_k127_1141402_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 350.0
DTH1_k127_1141402_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000001651 255.0
DTH1_k127_1141402_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000001354 203.0
DTH1_k127_1141402_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000004889 125.0
DTH1_k127_1145069_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.437e-219 688.0
DTH1_k127_1145069_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
DTH1_k127_1145069_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000003901 72.0
DTH1_k127_1180064_0 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 501.0
DTH1_k127_1180064_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000007466 244.0
DTH1_k127_1180064_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000004319 138.0
DTH1_k127_1201261_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 473.0
DTH1_k127_1201261_1 Virulence protein RhuM family - - - 0.0000000000005827 77.0
DTH1_k127_1201261_2 - - - - 0.0000025 55.0
DTH1_k127_1201261_3 Resolvase - - - 0.00005585 53.0
DTH1_k127_1204233_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 535.0
DTH1_k127_1204233_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002847 277.0
DTH1_k127_1204233_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007665 256.0
DTH1_k127_1216587_0 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000000208 206.0
DTH1_k127_1216587_1 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000002515 170.0
DTH1_k127_1216587_2 Type II secretory pathway pseudopilin - - - 0.0000000000000000000000000000000000000002303 161.0
DTH1_k127_1216587_3 Secretin and TonB N terminus short domain K02453 - - 0.00000000000000449 80.0
DTH1_k127_123760_0 O-acetylhomoserine K01740 - 2.5.1.49 3.228e-229 714.0
DTH1_k127_123760_1 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 502.0
DTH1_k127_123760_2 atpase or kinase K06925 - - 0.000000000000000000000000000000000000000000000000000000277 203.0
DTH1_k127_123760_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000008148 161.0
DTH1_k127_125149_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 389.0
DTH1_k127_125149_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000002649 184.0
DTH1_k127_125149_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000007566 117.0
DTH1_k127_1251563_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.192e-218 682.0
DTH1_k127_1251563_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000026 52.0
DTH1_k127_1266546_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 2.102e-239 762.0
DTH1_k127_1266546_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 583.0
DTH1_k127_1266546_10 Resolvase, N terminal domain - - - 0.000000001134 65.0
DTH1_k127_1266546_11 - - - - 0.0003573 49.0
DTH1_k127_1266546_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 472.0
DTH1_k127_1266546_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 408.0
DTH1_k127_1266546_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 365.0
DTH1_k127_1266546_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 330.0
DTH1_k127_1266546_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 321.0
DTH1_k127_1266546_7 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000244 251.0
DTH1_k127_1266546_8 Protein of unknown function (DUF1318) K09978 - - 0.000000000000000000000000000000000000000000000000001049 190.0
DTH1_k127_1266546_9 - - - - 0.0000000001393 64.0
DTH1_k127_127054_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.794e-252 784.0
DTH1_k127_1270564_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 7.566e-210 660.0
DTH1_k127_1270564_1 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
DTH1_k127_1270564_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000538 126.0
DTH1_k127_1281965_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
DTH1_k127_1281965_1 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000005964 213.0
DTH1_k127_1281965_2 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000004618 88.0
DTH1_k127_1281965_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000004151 68.0
DTH1_k127_1298889_0 AMP-binding enzyme C-terminal domain K00666 - - 2.623e-282 874.0
DTH1_k127_1298889_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.633e-226 707.0
DTH1_k127_1298889_10 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000006571 188.0
DTH1_k127_1298889_11 - - - - 0.0000000000000000000000000001415 119.0
DTH1_k127_1298889_12 - - - - 0.000000000000000007393 100.0
DTH1_k127_1298889_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000001617 61.0
DTH1_k127_1298889_2 ABC transporter K01999 - - 4.343e-198 624.0
DTH1_k127_1298889_3 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 572.0
DTH1_k127_1298889_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 493.0
DTH1_k127_1298889_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 430.0
DTH1_k127_1298889_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 415.0
DTH1_k127_1298889_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 422.0
DTH1_k127_1298889_8 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 402.0
DTH1_k127_1298889_9 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 380.0
DTH1_k127_1307333_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1012.0
DTH1_k127_1307333_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.5e-323 997.0
DTH1_k127_1307333_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000309 138.0
DTH1_k127_1307333_11 MnmE helical domain K03650 - - 0.0000000000000000000000000000000001276 134.0
DTH1_k127_1307333_12 Planctomycete cytochrome C - - - 0.0000000000000000000000000000001809 128.0
DTH1_k127_1307333_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 432.0
DTH1_k127_1307333_3 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 405.0
DTH1_k127_1307333_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 357.0
DTH1_k127_1307333_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 350.0
DTH1_k127_1307333_6 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
DTH1_k127_1307333_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000004916 235.0
DTH1_k127_1307333_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000008326 203.0
DTH1_k127_1307333_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000002549 199.0
DTH1_k127_1338179_0 PQQ-like domain K00114 - 1.1.2.8 1.434e-318 985.0
DTH1_k127_1338179_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
DTH1_k127_1338179_2 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 330.0
DTH1_k127_1338179_3 Sulphur oxidation protein SoxZ K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 298.0
DTH1_k127_1338179_4 helix_turn_helix, Lux Regulon K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005841 266.0
DTH1_k127_1338179_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002315 247.0
DTH1_k127_1338179_6 - - - - 0.00000000000000001119 97.0
DTH1_k127_1365103_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 351.0
DTH1_k127_1365103_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
DTH1_k127_1371650_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1727.0
DTH1_k127_1371650_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1011.0
DTH1_k127_1371650_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 419.0
DTH1_k127_1371650_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
DTH1_k127_1371650_4 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 385.0
DTH1_k127_1371650_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000005466 235.0
DTH1_k127_1371650_6 Pfam Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000005045 187.0
DTH1_k127_1380101_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 462.0
DTH1_k127_1380101_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 340.0
DTH1_k127_1380101_2 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001404 247.0
DTH1_k127_1380101_3 - - - - 0.000000000000006385 81.0
DTH1_k127_1382933_0 CoA-binding domain protein K09181 - - 1.113e-251 789.0
DTH1_k127_1397596_0 4Fe-4S double cluster binding domain K11473 - - 0.00000000000000000000000000000000000000000000002386 172.0
DTH1_k127_1397596_1 COG0695 Glutaredoxin and related proteins - - - 0.0000000000000000000000000000002785 129.0
DTH1_k127_1397596_2 SdpI/YhfL protein family - - - 0.0000000000000000007257 98.0
DTH1_k127_1402655_0 Ammonium Transporter K03320 - - 2.042e-218 684.0
DTH1_k127_1402655_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 1.278e-216 679.0
DTH1_k127_1402655_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 427.0
DTH1_k127_1402655_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 423.0
DTH1_k127_1402655_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000008903 168.0
DTH1_k127_1402655_5 Ammonium Transporter K03320 - - 0.00000000000000006792 84.0
DTH1_k127_1403297_0 MMPL family - - - 0.0 1338.0
DTH1_k127_1403297_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 329.0
DTH1_k127_1403297_2 transcriptional regulator - - - 0.0000000000000000000000000000000005403 131.0
DTH1_k127_1407204_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
DTH1_k127_1407204_1 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 265.0
DTH1_k127_1422488_0 TRAP transporter solute receptor TAXI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 455.0
DTH1_k127_1422488_1 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000054 259.0
DTH1_k127_1422488_2 Protein of unknown function (DUF2863) - - - 0.000000000000000000000000000000000000000000000000000000001732 203.0
DTH1_k127_1422488_3 YCII-related domain K09780 - - 0.0000000000000000000000000000000000000000005181 169.0
DTH1_k127_1422488_4 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000002221 113.0
DTH1_k127_1432801_0 PFAM ATPase associated with various cellular activities, AAA_3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 480.0
DTH1_k127_1432801_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
DTH1_k127_1432801_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000003338 133.0
DTH1_k127_1470476_0 Poly-beta-hydroxybutyrate K03821 - - 1.724e-211 672.0
DTH1_k127_1470476_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 5.66e-211 665.0
DTH1_k127_1470476_2 TrkA-N domain protein K03499 - - 7.984e-205 647.0
DTH1_k127_1470476_3 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 469.0
DTH1_k127_1470476_4 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 354.0
DTH1_k127_1470476_5 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
DTH1_k127_1470476_6 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000002247 198.0
DTH1_k127_1470476_7 PFAM CheW domain protein K02659 - - 0.00000000000000000000000000000000000000000009222 168.0
DTH1_k127_1470476_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000001887 58.0
DTH1_k127_1484984_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 519.0
DTH1_k127_1484984_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 535.0
DTH1_k127_1484984_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 357.0
DTH1_k127_1484984_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 341.0
DTH1_k127_1485002_0 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
DTH1_k127_1485002_1 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 334.0
DTH1_k127_1485002_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
DTH1_k127_1485002_3 TIGRFAM DnaA regulatory inactivator Hda K10763 - - 0.0000000000000000000000000000722 117.0
DTH1_k127_1485002_4 ABC transporter K02013 - 3.6.3.34 0.0000000000000001181 93.0
DTH1_k127_1487911_0 Cysteine-rich domain - - - 8.387e-229 718.0
DTH1_k127_1487911_1 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009118 273.0
DTH1_k127_1487911_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
DTH1_k127_1487911_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000002881 214.0
DTH1_k127_148982_0 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 384.0
DTH1_k127_148982_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001572 274.0
DTH1_k127_148982_2 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000007358 219.0
DTH1_k127_148982_3 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000001807 178.0
DTH1_k127_1535985_0 Response regulator receiver K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 598.0
DTH1_k127_1535985_1 PFAM Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 537.0
DTH1_k127_1535985_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002447 106.0
DTH1_k127_1535985_3 Sel1-like repeats. K07126 - - 0.000000000000001363 86.0
DTH1_k127_154602_0 GGDEF domain - - - 6.986e-219 696.0
DTH1_k127_154602_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000003661 181.0
DTH1_k127_1558163_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 497.0
DTH1_k127_1558163_1 Transferase hexapeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000008015 231.0
DTH1_k127_1558163_2 Haem-degrading - - - 0.00000000000000000000000000000000000003609 159.0
DTH1_k127_1561004_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 467.0
DTH1_k127_1561004_1 Fe-S protein - - - 0.00006946 49.0
DTH1_k127_1583832_0 Insertion element 4 transposase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 414.0
DTH1_k127_1583832_1 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.000000000000000000000000000000131 127.0
DTH1_k127_1583832_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000002285 82.0
DTH1_k127_1585807_0 Multicopper oxidase K22349 - 1.16.3.3 7.203e-214 677.0
DTH1_k127_159598_0 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000001208 162.0
DTH1_k127_1597740_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.819e-220 690.0
DTH1_k127_1597740_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 595.0
DTH1_k127_1597740_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000004131 74.0
DTH1_k127_1619562_0 Malic enzyme K00029 - 1.1.1.40 0.0 1044.0
DTH1_k127_1644848_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000002351 233.0
DTH1_k127_1644848_1 overlaps another CDS with the same product name - - - 0.000000000001091 80.0
DTH1_k127_1658084_0 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 357.0
DTH1_k127_1658084_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 324.0
DTH1_k127_1658084_2 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000004506 189.0
DTH1_k127_1658084_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000007625 72.0
DTH1_k127_1719437_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.974e-211 665.0
DTH1_k127_1719437_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 374.0
DTH1_k127_1719437_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 308.0
DTH1_k127_1719437_3 esterase, PHB depolymerase - - - 0.0000000000000000000000000000000000000000001951 177.0
DTH1_k127_1725423_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.612e-255 794.0
DTH1_k127_1725423_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 480.0
DTH1_k127_1725423_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 477.0
DTH1_k127_1749839_0 RNA polymerase sigma factor K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 412.0
DTH1_k127_1749839_1 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000001831 187.0
DTH1_k127_1753548_0 FeS assembly protein SufB K09014 - - 3.09e-276 855.0
DTH1_k127_1753548_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 589.0
DTH1_k127_1753548_10 NnrU protein - - - 0.000001289 51.0
DTH1_k127_1753548_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 456.0
DTH1_k127_1753548_3 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
DTH1_k127_1753548_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
DTH1_k127_1753548_5 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
DTH1_k127_1753548_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002666 172.0
DTH1_k127_1753548_7 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.00000000000000000000000000000000000000006405 154.0
DTH1_k127_1753548_8 PaaD-like protein - - - 0.00000000000000000000000000000000000002592 146.0
DTH1_k127_1753548_9 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000004651 128.0
DTH1_k127_175409_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 589.0
DTH1_k127_175409_1 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000001592 154.0
DTH1_k127_175409_2 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000000000004818 156.0
DTH1_k127_175409_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000001015 137.0
DTH1_k127_175409_4 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000001395 68.0
DTH1_k127_17572_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 332.0
DTH1_k127_17572_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000002087 233.0
DTH1_k127_17572_2 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000002968 197.0
DTH1_k127_1777509_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1428.0
DTH1_k127_1777509_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 475.0
DTH1_k127_1777509_2 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 471.0
DTH1_k127_1777509_3 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 387.0
DTH1_k127_179751_0 PFAM FMN-binding domain protein K19339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 566.0
DTH1_k127_179751_1 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 331.0
DTH1_k127_180443_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 505.0
DTH1_k127_180443_1 abc transporter K06158 - - 0.0000003157 54.0
DTH1_k127_1821139_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 8.338e-248 771.0
DTH1_k127_1821139_2 Beta-lactamase - - - 0.00001663 48.0
DTH1_k127_1882947_0 aminopeptidase N K01256 - 3.4.11.2 2.142e-266 831.0
DTH1_k127_1882947_1 Divalent cation transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000005379 237.0
DTH1_k127_1882947_2 - - - - 0.0000000000000000000000000000000000000001052 169.0
DTH1_k127_19267_0 PFAM aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 503.0
DTH1_k127_19267_1 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 511.0
DTH1_k127_19267_2 Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 467.0
DTH1_k127_19267_3 zinc protease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
DTH1_k127_19267_4 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 342.0
DTH1_k127_19267_5 Complex I intermediate-associated protein 30 (CIA30) - - - 0.00000000000000000000000000000002383 133.0
DTH1_k127_19267_6 Flavin containing amine oxidoreductase K06954 - - 0.00000000000089 68.0
DTH1_k127_196217_0 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 348.0
DTH1_k127_196217_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
DTH1_k127_196217_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000005445 192.0
DTH1_k127_1993258_0 Protein kinase domain K12132 - 2.7.11.1 3.069e-202 659.0
DTH1_k127_2015971_0 - - - - 0.000000000000000000000000000000000001836 154.0
DTH1_k127_2015971_1 beta-galactosidase activity K01190,K01195 - 3.2.1.23,3.2.1.31 0.00000000000001689 74.0
DTH1_k127_2045275_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 553.0
DTH1_k127_2045275_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 511.0
DTH1_k127_2045275_2 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 312.0
DTH1_k127_2045275_3 - - - - 0.000000004176 60.0
DTH1_k127_2056629_0 polyphosphate kinase - - - 3.911e-230 722.0
DTH1_k127_2056629_1 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009967 249.0
DTH1_k127_2056629_2 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000001481 94.0
DTH1_k127_2089820_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 541.0
DTH1_k127_2089820_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000004171 188.0
DTH1_k127_2089820_2 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.000000989 55.0
DTH1_k127_2090981_0 Malic enzyme K00029 - 1.1.1.40 0.0 1077.0
DTH1_k127_2090981_1 elongation factor G K02355 - - 5e-324 1005.0
DTH1_k127_2090981_10 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000008404 145.0
DTH1_k127_2090981_11 - - - - 0.00000000000000000000000000000001337 128.0
DTH1_k127_2090981_12 - - - - 0.00000000000001998 80.0
DTH1_k127_2090981_13 Outer membrane lipoprotein K07285 - - 0.0006833 51.0
DTH1_k127_2090981_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
DTH1_k127_2090981_3 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
DTH1_k127_2090981_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 284.0
DTH1_k127_2090981_5 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
DTH1_k127_2090981_6 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
DTH1_k127_2090981_7 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000006062 181.0
DTH1_k127_2090981_8 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000002265 153.0
DTH1_k127_2090981_9 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001151 144.0
DTH1_k127_2091854_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2465.0
DTH1_k127_2091854_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 529.0
DTH1_k127_2091854_2 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000002691 150.0
DTH1_k127_2116095_0 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 432.0
DTH1_k127_2116095_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 294.0
DTH1_k127_2116095_2 GtrA-like protein - - - 0.000000000000000000000000178 112.0
DTH1_k127_2124197_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 339.0
DTH1_k127_2124197_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000001025 171.0
DTH1_k127_2124197_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000004813 147.0
DTH1_k127_2158644_0 Homospermidine synthase K00808 - 2.5.1.44 2.005e-216 684.0
DTH1_k127_2158644_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 332.0
DTH1_k127_2158644_2 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000001547 213.0
DTH1_k127_2158644_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000001888 179.0
DTH1_k127_2158644_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000003476 71.0
DTH1_k127_2158644_5 Protein of unknown function (DUF3567) - - - 0.00000000001197 68.0
DTH1_k127_2170801_0 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000001719 155.0
DTH1_k127_2170801_1 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000211 112.0
DTH1_k127_2170801_2 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000002475 83.0
DTH1_k127_2187598_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 547.0
DTH1_k127_2187598_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 310.0
DTH1_k127_2191541_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.476e-321 999.0
DTH1_k127_2191541_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000001059 236.0
DTH1_k127_2191541_2 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000003542 188.0
DTH1_k127_2191541_3 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000003242 136.0
DTH1_k127_2199935_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1034.0
DTH1_k127_2226538_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.148e-283 875.0
DTH1_k127_2226538_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
DTH1_k127_2226538_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000004435 125.0
DTH1_k127_2226538_3 Domain of unknown function (DUF4845) - - - 0.000000000000000000003672 100.0
DTH1_k127_2254154_0 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 420.0
DTH1_k127_2254154_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 315.0
DTH1_k127_2254154_2 LUD domain K00782 - - 0.00000000000000000000000000000002139 127.0
DTH1_k127_2272542_0 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 484.0
DTH1_k127_2272542_1 4Fe-4S binding domain K05524 - - 0.000000000000000000000000000000000002478 142.0
DTH1_k127_2272542_2 formylmethanofuran dehydrogenase, subunit K00201 - 1.2.7.12 0.0000000000000000000004263 100.0
DTH1_k127_2272542_3 PFAM molydopterin dinucleotide-binding region K00203,K00336 - 1.2.7.12,1.6.5.3 0.00000000000000003861 85.0
DTH1_k127_2273862_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.146e-262 820.0
DTH1_k127_2273862_1 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000005137 229.0
DTH1_k127_2273862_2 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000001118 180.0
DTH1_k127_2273862_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000718 69.0
DTH1_k127_2273862_4 KR domain - - - 0.000002572 58.0
DTH1_k127_2405848_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.251e-208 658.0
DTH1_k127_2466886_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 495.0
DTH1_k127_2466886_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
DTH1_k127_2466886_2 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002373 284.0
DTH1_k127_2466886_3 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 265.0
DTH1_k127_252751_0 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 323.0
DTH1_k127_252751_1 plastoquinol--plastocyanin reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000001465 210.0
DTH1_k127_252751_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000002661 136.0
DTH1_k127_2536771_0 COG1520 FOG WD40-like repeat - - - 0.0000002556 63.0
DTH1_k127_2538678_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.817e-207 653.0
DTH1_k127_2538678_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
DTH1_k127_2538678_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000323 184.0
DTH1_k127_2560843_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 399.0
DTH1_k127_2560843_1 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 278.0
DTH1_k127_2560843_2 SCP-2 sterol transfer family - - - 0.00000000000000000000001392 102.0
DTH1_k127_256512_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 - 1.2.7.1 0.0 2070.0
DTH1_k127_2578985_0 transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 538.0
DTH1_k127_2578985_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 359.0
DTH1_k127_2578985_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005023 278.0
DTH1_k127_2578985_3 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000002015 203.0
DTH1_k127_2578985_4 Ferredoxin - - - 0.000000000000000000000000000000007675 128.0
DTH1_k127_2578985_5 Ankyrin repeats (many copies) - GO:0003008,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0007010,GO:0007015,GO:0007600,GO:0007605,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0032420,GO:0032421,GO:0032426,GO:0032501,GO:0042995,GO:0043005,GO:0043226,GO:0044085,GO:0044422,GO:0044424,GO:0044463,GO:0044464,GO:0044877,GO:0050877,GO:0050954,GO:0051015,GO:0051017,GO:0061572,GO:0071840,GO:0097435,GO:0097458,GO:0098858,GO:0098862,GO:0120025,GO:0120038 - 0.00009613 48.0
DTH1_k127_2580609_0 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 422.0
DTH1_k127_2583502_0 - - - - 0.000000000000000000000000000000000000000000000000000000000004416 219.0
DTH1_k127_2583502_1 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000001154 143.0
DTH1_k127_2589555_0 Belongs to the GMC oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 359.0
DTH1_k127_2589555_1 - - - - 0.000000005066 61.0
DTH1_k127_2595690_0 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000003426 195.0
DTH1_k127_2597547_0 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 544.0
DTH1_k127_2597547_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
DTH1_k127_2597547_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 371.0
DTH1_k127_2613904_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 5.907e-206 642.0
DTH1_k127_2613904_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 320.0
DTH1_k127_2613904_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000003643 162.0
DTH1_k127_2613904_3 - - - - 0.000000000000000000000000000000000000000003549 161.0
DTH1_k127_2613904_4 Acyl carrier protein phosphodiesterase - - - 0.00000000000000000000000000000000000000897 145.0
DTH1_k127_2613904_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000005105 104.0
DTH1_k127_2613904_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000004181 87.0
DTH1_k127_2630190_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.461e-254 791.0
DTH1_k127_2630190_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 4.412e-194 611.0
DTH1_k127_2630190_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 522.0
DTH1_k127_2630190_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 360.0
DTH1_k127_2630190_4 pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 295.0
DTH1_k127_2658027_0 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 524.0
DTH1_k127_2658027_1 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 368.0
DTH1_k127_2686134_0 Protein of unknown function (DUF3141) - - - 0.0 1032.0
DTH1_k127_2686134_1 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 1.109e-241 760.0
DTH1_k127_2686134_10 - - - - 0.00000000000000000000000003099 110.0
DTH1_k127_2686134_11 - - - - 0.00000000000000002774 87.0
DTH1_k127_2686134_12 - - - - 0.0000000028 63.0
DTH1_k127_2686134_13 - - - - 0.000000008634 58.0
DTH1_k127_2686134_14 - - - - 0.00001554 50.0
DTH1_k127_2686134_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 572.0
DTH1_k127_2686134_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 549.0
DTH1_k127_2686134_4 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 462.0
DTH1_k127_2686134_5 phosphate K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 460.0
DTH1_k127_2686134_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 437.0
DTH1_k127_2686134_7 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002601 205.0
DTH1_k127_2686134_8 lipid catabolic process - - - 0.0000000000000000000000000000000000000000000005543 184.0
DTH1_k127_2686134_9 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000005469 149.0
DTH1_k127_2688969_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 347.0
DTH1_k127_2688969_1 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000008641 256.0
DTH1_k127_2688969_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000002082 121.0
DTH1_k127_2688969_3 Glycine zipper 2TM domain - - - 0.0000000000000000000005576 97.0
DTH1_k127_2698661_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.63e-237 741.0
DTH1_k127_2698661_1 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 409.0
DTH1_k127_2698661_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 369.0
DTH1_k127_2698661_3 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000006979 199.0
DTH1_k127_2698661_4 RDD family - - - 0.00000000000000000000000000002258 120.0
DTH1_k127_2702367_0 Belongs to the HypD family K04654 - - 2.347e-198 627.0
DTH1_k127_2702367_1 Formyl transferase K19640 - - 4.6e-198 626.0
DTH1_k127_2702367_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 583.0
DTH1_k127_2702367_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000001182 193.0
DTH1_k127_2702367_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000001181 117.0
DTH1_k127_2703734_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 600.0
DTH1_k127_2703734_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 486.0
DTH1_k127_2703734_2 peptidase U62, modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 328.0
DTH1_k127_2703734_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003661 244.0
DTH1_k127_2703734_4 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
DTH1_k127_2738954_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 357.0
DTH1_k127_2738954_1 Belongs to the enoyl-CoA hydratase isomerase family K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001028 265.0
DTH1_k127_2738954_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000136 246.0
DTH1_k127_2738954_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000005325 231.0
DTH1_k127_2738954_4 Ribonuclease T2 family - - - 0.000000000000000000000000000000000000000000000002575 179.0
DTH1_k127_2745219_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 9.938e-219 685.0
DTH1_k127_2745219_1 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 313.0
DTH1_k127_2745219_2 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000007831 246.0
DTH1_k127_2745219_3 - - - - 0.0000000000000000000000000000000004636 138.0
DTH1_k127_2745219_4 - - - - 0.000000146 55.0
DTH1_k127_2759475_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.436e-251 781.0
DTH1_k127_2759475_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 4.958e-227 711.0
DTH1_k127_2759475_2 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002756 275.0
DTH1_k127_2759475_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000001412 76.0
DTH1_k127_2759801_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 280.0
DTH1_k127_2759801_1 PIN domain - - - 0.000000000000000000000000000000000000000000007808 171.0
DTH1_k127_2759801_2 Domain of unknown function (DUF3368) - - - 0.000000000000000000000000000000000000005054 151.0
DTH1_k127_2759801_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000009286 140.0
DTH1_k127_2759801_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000003046 121.0
DTH1_k127_2759801_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000002608 119.0
DTH1_k127_2759801_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000001282 93.0
DTH1_k127_2759801_7 23S rRNA-intervening sequence protein - - - 0.00000000000000003471 82.0
DTH1_k127_2780096_0 4Fe-4S binding domain - - - 0.0 1044.0
DTH1_k127_2780096_1 Periplasmic copper-binding protein (NosD) K07218 - - 2.89e-211 670.0
DTH1_k127_2780096_2 Cytochrome C oxidase subunit II, periplasmic domain protein K00376 - 1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 581.0
DTH1_k127_2780096_3 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 427.0
DTH1_k127_2780096_4 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 404.0
DTH1_k127_2780096_5 NosL K19342 - - 0.00000000000000000000000000000000000000000000000000000000000001903 231.0
DTH1_k127_2780096_6 domain, Protein - - - 0.000000000000000000000000000000000000000000000005737 177.0
DTH1_k127_2780096_7 - - - - 0.0000000000000000000000000000000001416 139.0
DTH1_k127_2780096_8 - - - - 0.000000000000000000002895 96.0
DTH1_k127_2816664_0 type IV-A pilus assembly ATPase PilB K02652 - - 1.185e-250 785.0
DTH1_k127_2816664_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.16e-218 685.0
DTH1_k127_2816664_2 PFAM type II secretion system K02653 - - 2.504e-201 632.0
DTH1_k127_2816664_3 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 571.0
DTH1_k127_2816664_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 431.0
DTH1_k127_2816664_5 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 383.0
DTH1_k127_2816664_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000004976 132.0
DTH1_k127_2816664_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000001343 90.0
DTH1_k127_2816664_8 Dephospho-CoA kinase K00859 - 2.7.1.24 0.0000000000002571 80.0
DTH1_k127_282395_0 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 560.0
DTH1_k127_282395_1 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 312.0
DTH1_k127_282395_2 - - - - 0.000000000000000000000000000000000001358 142.0
DTH1_k127_282395_3 - - - - 0.000000000000000002773 85.0
DTH1_k127_2829971_0 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000006309 211.0
DTH1_k127_2829971_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000003027 133.0
DTH1_k127_2829971_2 - - - - 0.000000000001507 74.0
DTH1_k127_2868891_0 type IV pilus secretin PilQ K02666 - - 2.617e-228 741.0
DTH1_k127_2868891_1 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003938 252.0
DTH1_k127_2868891_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000134 223.0
DTH1_k127_2868891_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000002855 177.0
DTH1_k127_2868891_4 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000002193 180.0
DTH1_k127_2870264_0 twitching motility protein K02670 - - 6.135e-201 630.0
DTH1_k127_2870264_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 603.0
DTH1_k127_2870264_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000008196 184.0
DTH1_k127_2870264_3 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000005944 99.0
DTH1_k127_2893766_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 309.0
DTH1_k127_2893766_1 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000003606 181.0
DTH1_k127_2893766_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000003252 154.0
DTH1_k127_2893766_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000001735 91.0
DTH1_k127_2899257_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.017e-210 663.0
DTH1_k127_2899257_1 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
DTH1_k127_2899257_2 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002046 270.0
DTH1_k127_2899257_3 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000000000003508 228.0
DTH1_k127_2899257_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000002769 225.0
DTH1_k127_2899257_5 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000001392 168.0
DTH1_k127_2899257_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000003609 152.0
DTH1_k127_2899257_7 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000001421 115.0
DTH1_k127_2899257_8 psiF repeat - - - 0.00000000000000000001688 102.0
DTH1_k127_2899257_9 - - - - 0.00000004448 58.0
DTH1_k127_2917921_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001498 253.0
DTH1_k127_2917921_1 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000004705 205.0
DTH1_k127_2917921_2 Histidine kinase K19661 - 2.7.13.3 0.0000000000000000000000000000000004554 143.0
DTH1_k127_2917921_3 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000006485 126.0
DTH1_k127_2942813_0 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 437.0
DTH1_k127_2942813_1 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004876 276.0
DTH1_k127_2942813_2 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000006879 189.0
DTH1_k127_2942813_3 - - - - 0.0000000001112 64.0
DTH1_k127_2950269_0 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 462.0
DTH1_k127_2950269_1 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000000000000000000000008412 230.0
DTH1_k127_2950269_2 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000004814 168.0
DTH1_k127_2950269_3 - - - - 0.00000000000000000000000000000000006789 149.0
DTH1_k127_2950269_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000001616 89.0
DTH1_k127_2951028_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 7.221e-194 614.0
DTH1_k127_2951028_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
DTH1_k127_2951028_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
DTH1_k127_2951028_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000003321 248.0
DTH1_k127_2951028_4 ABC transporter K02003 - - 0.00000000004408 77.0
DTH1_k127_2951542_0 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 432.0
DTH1_k127_2951542_1 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000003018 186.0
DTH1_k127_2960242_0 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000001731 96.0
DTH1_k127_2960242_1 Cytochrome C assembly protein - - - 0.00000000000002101 86.0
DTH1_k127_2960242_2 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000003871 68.0
DTH1_k127_2973962_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1027.0
DTH1_k127_2973962_1 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 296.0
DTH1_k127_2973962_2 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000237 277.0
DTH1_k127_2987783_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 501.0
DTH1_k127_2987783_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 419.0
DTH1_k127_2987783_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 331.0
DTH1_k127_2987783_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006707 280.0
DTH1_k127_2987783_4 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000000000298 152.0
DTH1_k127_2987783_5 Diguanylate cyclase - - - 0.0000000000000000241 83.0
DTH1_k127_3012822_0 small subunit K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 1.853e-198 625.0
DTH1_k127_3012822_1 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 382.0
DTH1_k127_3012822_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003005 235.0
DTH1_k127_3012822_3 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000000005207 164.0
DTH1_k127_3012822_4 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000003336 108.0
DTH1_k127_3014349_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 381.0
DTH1_k127_3014349_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 379.0
DTH1_k127_3014349_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 327.0
DTH1_k127_3014349_3 Glyoxalase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001698 236.0
DTH1_k127_3014349_4 Rubredoxin - - - 0.000000000000000000000000811 118.0
DTH1_k127_3014349_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000003284 91.0
DTH1_k127_3014349_6 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000003585 59.0
DTH1_k127_3024717_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 9.695e-207 650.0
DTH1_k127_3024717_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 329.0
DTH1_k127_3024717_2 Glycine zipper - - - 0.00000000000000000000000000000000000000000000000000000003133 203.0
DTH1_k127_3051533_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 656.0
DTH1_k127_3051533_2 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 364.0
DTH1_k127_3051744_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 344.0
DTH1_k127_3051744_1 - - - - 0.0000000000000000000000000000000000000000009826 165.0
DTH1_k127_3051744_2 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.00000000000000000000000000001951 117.0
DTH1_k127_3056512_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 509.0
DTH1_k127_3056512_1 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
DTH1_k127_3056512_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000007284 167.0
DTH1_k127_3056512_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000003258 152.0
DTH1_k127_3056512_4 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000001255 132.0
DTH1_k127_3056512_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002148 90.0
DTH1_k127_3056512_6 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000007114 78.0
DTH1_k127_3062184_0 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 568.0
DTH1_k127_3062184_1 Diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 320.0
DTH1_k127_3062184_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000001713 203.0
DTH1_k127_3063418_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.192e-218 683.0
DTH1_k127_3063418_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 304.0
DTH1_k127_3063418_2 - - - - 0.000000000000000000000000000000003408 133.0
DTH1_k127_3063418_3 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000002866 131.0
DTH1_k127_3072081_0 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 560.0
DTH1_k127_3072081_1 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000003623 247.0
DTH1_k127_3074887_0 Male sterility - - - 5.132e-284 887.0
DTH1_k127_3074887_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
DTH1_k127_3074887_2 Bacterial transcriptional repressor - - - 0.00000000000000000000000000000000006087 137.0
DTH1_k127_3074887_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000003951 138.0
DTH1_k127_3074887_4 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000003032 136.0
DTH1_k127_3076177_0 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 490.0
DTH1_k127_3076177_1 type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000003644 214.0
DTH1_k127_3079356_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 411.0
DTH1_k127_3079356_1 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000006489 192.0
DTH1_k127_3079356_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000003422 175.0
DTH1_k127_3079356_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000004882 113.0
DTH1_k127_3083391_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 596.0
DTH1_k127_3083391_1 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 326.0
DTH1_k127_3099012_0 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009398 245.0
DTH1_k127_3099012_1 PFAM transcription elongation factor GreA GreB - - - 0.00000000000000000000000000000000000000000000007137 178.0
DTH1_k127_3099012_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000005436 67.0
DTH1_k127_3099012_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000001279 63.0
DTH1_k127_3099308_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 602.0
DTH1_k127_3099308_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 466.0
DTH1_k127_3099308_2 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 344.0
DTH1_k127_310745_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 499.0
DTH1_k127_3113823_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 591.0
DTH1_k127_3113823_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 334.0
DTH1_k127_3113823_2 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 293.0
DTH1_k127_3113823_3 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000004574 162.0
DTH1_k127_3168122_0 Fumarase C C-terminus K01744 - 4.3.1.1 4.272e-271 844.0
DTH1_k127_3168122_1 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 2.388e-245 762.0
DTH1_k127_3168122_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 532.0
DTH1_k127_3168122_3 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000006391 202.0
DTH1_k127_3173137_0 Sigma-54 interaction domain K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008112 604.0
DTH1_k127_3173137_1 Belongs to the UPF0337 (CsbD) family - - - 0.000000776 55.0
DTH1_k127_3173137_2 - - - - 0.00004623 51.0
DTH1_k127_3173343_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000005019 240.0
DTH1_k127_3173343_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000002106 179.0
DTH1_k127_3175524_0 Transport of potassium into the cell K03549 - - 3.91e-273 853.0
DTH1_k127_3175524_1 response regulator K08083 - - 0.0000000000000000000000000000000000000001579 153.0
DTH1_k127_3191906_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.373e-318 987.0
DTH1_k127_3191906_1 COG1982 Arginine lysine ornithine decarboxylases K01584 - 4.1.1.19 5.85e-204 637.0
DTH1_k127_3191906_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 570.0
DTH1_k127_3191906_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 372.0
DTH1_k127_3191906_4 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003377 251.0
DTH1_k127_319471_0 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 504.0
DTH1_k127_319471_1 type II secretion system protein E K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 319.0
DTH1_k127_319471_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002846 288.0
DTH1_k127_3211590_0 Peptidase, M50 family K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 453.0
DTH1_k127_3211590_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
DTH1_k127_3222215_0 Tripartite tricarboxylate transporter TctA family K07793 - - 6.552e-256 796.0
DTH1_k127_3222215_1 AMP-binding enzyme C-terminal domain K18661 - - 1.664e-208 659.0
DTH1_k127_3222215_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000008933 132.0
DTH1_k127_3222215_11 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000001437 117.0
DTH1_k127_3222215_2 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 578.0
DTH1_k127_3222215_3 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 535.0
DTH1_k127_3222215_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 527.0
DTH1_k127_3222215_5 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 463.0
DTH1_k127_3222215_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 377.0
DTH1_k127_3222215_7 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
DTH1_k127_3222215_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 345.0
DTH1_k127_3222215_9 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000003318 160.0
DTH1_k127_3230206_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
DTH1_k127_3235266_0 Zinc-binding dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 514.0
DTH1_k127_3235266_1 Aldo keto reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 408.0
DTH1_k127_3235266_2 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.000000000000000000000000000000000000000000000000000000000007811 211.0
DTH1_k127_3235266_3 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000002564 150.0
DTH1_k127_3241251_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1244.0
DTH1_k127_3241251_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 548.0
DTH1_k127_3241251_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
DTH1_k127_3241251_3 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 432.0
DTH1_k127_3241251_4 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000002813 232.0
DTH1_k127_3241251_5 Molecular chaperone K05516 - - 0.000000000000000000000000000000000000000000004497 166.0
DTH1_k127_3241251_6 Belongs to the SfsA family K01892,K06206 - 6.1.1.21 0.00000000000000000000000000000007329 129.0
DTH1_k127_3241251_7 MerR HTH family regulatory protein K18997 - - 0.00000000004978 68.0
DTH1_k127_3245260_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.312e-209 657.0
DTH1_k127_3245260_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 369.0
DTH1_k127_3245260_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
DTH1_k127_3245260_3 DNA polymerase III, delta' K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000001287 199.0
DTH1_k127_3245938_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 334.0
DTH1_k127_3272168_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 433.0
DTH1_k127_3272168_1 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007116 238.0
DTH1_k127_3272168_2 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001474 213.0
DTH1_k127_3272168_3 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000001994 203.0
DTH1_k127_3272168_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000001857 113.0
DTH1_k127_3297840_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
DTH1_k127_3297840_1 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003449 225.0
DTH1_k127_3297840_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000104 203.0
DTH1_k127_3297840_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000004947 205.0
DTH1_k127_3326571_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 541.0
DTH1_k127_3326571_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000001252 235.0
DTH1_k127_3326571_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000002179 209.0
DTH1_k127_3379600_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 9.067e-216 673.0
DTH1_k127_3379600_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 316.0
DTH1_k127_3385513_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.805e-204 657.0
DTH1_k127_3405760_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 595.0
DTH1_k127_3405760_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000005329 112.0
DTH1_k127_3411218_0 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 292.0
DTH1_k127_3411218_1 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 269.0
DTH1_k127_3411218_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
DTH1_k127_3411218_3 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000352 224.0
DTH1_k127_3411218_4 Rubredoxin - - - 0.000000000000000000000000009988 119.0
DTH1_k127_341417_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 582.0
DTH1_k127_341417_1 Belongs to the globin family - - - 0.000000000000000000000000008218 117.0
DTH1_k127_341417_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000004385 67.0
DTH1_k127_341417_3 Cytochrome c - - - 0.0003116 44.0
DTH1_k127_3424129_0 Multicopper oxidase K22349 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
DTH1_k127_3424129_1 Cytochrome c-type biogenesis protein - - - 0.0000000002197 71.0
DTH1_k127_3428825_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 393.0
DTH1_k127_3428825_1 His Kinase A (phospho-acceptor) domain K07711 - 2.7.13.3 0.0000000000000000000000003194 110.0
DTH1_k127_3446790_0 Peptidase M1 membrane alanine aminopeptidase - - - 3.145e-221 707.0
DTH1_k127_3446790_1 Sugar (and other) transporter - - - 7.398e-201 638.0
DTH1_k127_3446790_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 487.0
DTH1_k127_3446790_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 461.0
DTH1_k127_3446790_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
DTH1_k127_3458377_0 PFAM FMN-binding domain protein K19339 - - 0.0000000000000000000000000000000000000000000000000005509 192.0
DTH1_k127_3458377_1 - - - - 0.000000000000000000000000000000000000000000001274 173.0
DTH1_k127_3458377_2 - - - - 0.000000000000005965 81.0
DTH1_k127_3458377_3 TraB family K09973 - - 0.0000000007394 63.0
DTH1_k127_346030_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 538.0
DTH1_k127_346030_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000274 94.0
DTH1_k127_3465090_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 379.0
DTH1_k127_3465090_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008761 277.0
DTH1_k127_3465090_2 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001489 261.0
DTH1_k127_3465090_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000006531 218.0
DTH1_k127_3466836_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 461.0
DTH1_k127_3466836_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000006816 232.0
DTH1_k127_3474659_0 Belongs to the GPI family K01810 - 5.3.1.9 2.04e-266 828.0
DTH1_k127_3474659_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 402.0
DTH1_k127_3474659_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000003167 92.0
DTH1_k127_3504117_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 9.192e-312 970.0
DTH1_k127_3504117_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 8.571e-196 621.0
DTH1_k127_3504117_2 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 453.0
DTH1_k127_3504117_3 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 402.0
DTH1_k127_3504117_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000003408 194.0
DTH1_k127_3504117_5 blue (type 1) copper - - - 0.0000000000000000000001589 99.0
DTH1_k127_3509530_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 569.0
DTH1_k127_3509530_1 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
DTH1_k127_3509530_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000005034 71.0
DTH1_k127_3512334_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 528.0
DTH1_k127_3512334_1 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000007959 162.0
DTH1_k127_3512334_2 - - - - 0.000000000000000000000000000000000001337 148.0
DTH1_k127_3512334_3 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000004112 98.0
DTH1_k127_3521462_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000008325 198.0
DTH1_k127_3521462_1 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000004758 170.0
DTH1_k127_3529380_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 312.0
DTH1_k127_3529380_1 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 282.0
DTH1_k127_3529380_2 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000000000000000000000001184 247.0
DTH1_k127_3529380_3 nitrogen regulatory protein P-II - - - 0.0000000000001795 71.0
DTH1_k127_3533590_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 314.0
DTH1_k127_3533590_1 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000002135 271.0
DTH1_k127_3533590_3 - - - - 0.0000000789 55.0
DTH1_k127_3537688_0 orn lys arg decarboxylase K01584 - 4.1.1.19 4.785e-264 816.0
DTH1_k127_3537688_1 Glucose sorbosone K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 508.0
DTH1_k127_3537688_2 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 399.0
DTH1_k127_3537688_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 376.0
DTH1_k127_3537688_4 Protein of unknown function (DUF560) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 361.0
DTH1_k127_3537688_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 352.0
DTH1_k127_3537688_6 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 319.0
DTH1_k127_3537688_7 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000597 241.0
DTH1_k127_3550316_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 503.0
DTH1_k127_3550316_1 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.000000000000000000000002002 104.0
DTH1_k127_3555506_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 1.202e-210 668.0
DTH1_k127_3555506_1 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 330.0
DTH1_k127_3604221_0 transposition - - - 2.086e-211 664.0
DTH1_k127_3604221_1 Acetyl xylan esterase (AXE1) - - - 0.00008702 45.0
DTH1_k127_3640789_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000002075 195.0
DTH1_k127_3640789_1 Phasin protein - - - 0.0000000000000000000000000000000000009384 145.0
DTH1_k127_3640789_2 Dioxygenase - - - 0.000000000000000000000002993 107.0
DTH1_k127_3655287_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 340.0
DTH1_k127_3655287_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000006967 143.0
DTH1_k127_3655287_2 Biopolymer transport protein K03559 - - 0.000000000000000000000000000001344 128.0
DTH1_k127_366205_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1255.0
DTH1_k127_366205_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 2.255e-198 647.0
DTH1_k127_366205_2 ATP adenylyltransferase K00988 - 2.7.7.53 0.00000000000000000000000000000001117 133.0
DTH1_k127_366205_3 - - - - 0.0000000000000000003933 94.0
DTH1_k127_366532_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.843e-204 649.0
DTH1_k127_366532_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 473.0
DTH1_k127_366532_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000008558 254.0
DTH1_k127_366532_3 GTP binding - - - 0.00000000000000005083 95.0
DTH1_k127_3667115_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 498.0
DTH1_k127_3667115_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
DTH1_k127_3667115_2 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 282.0
DTH1_k127_3667115_3 FOG HPt domain K20976 - - 0.000003812 51.0
DTH1_k127_3677073_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 7.347e-224 710.0
DTH1_k127_3677846_0 IS66 C-terminal element - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 451.0
DTH1_k127_3677846_1 PFAM IS66 Orf2 like protein K07484 - - 0.00000000000000000000000000004626 125.0
DTH1_k127_3682938_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000001808 276.0
DTH1_k127_3682938_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000002381 244.0
DTH1_k127_3682938_2 Belongs to the peptidase M48B family - - - 0.000000000000000000000000000000000000000000000000000000003257 212.0
DTH1_k127_3682938_3 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.00000000000000000000000000000000000000000000000001266 187.0
DTH1_k127_3682938_4 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000006805 52.0
DTH1_k127_3720069_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 517.0
DTH1_k127_3720069_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 495.0
DTH1_k127_3720069_2 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 445.0
DTH1_k127_3720069_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 267.0
DTH1_k127_3720069_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000001212 280.0
DTH1_k127_3720069_5 Protein of unknown function (DUF493) K09158 - - 0.000000000000000000000000000001216 122.0
DTH1_k127_3720069_6 Thioredoxin-like - - - 0.00000000000000000000000000007437 124.0
DTH1_k127_3723029_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 401.0
DTH1_k127_3723029_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 333.0
DTH1_k127_3723029_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 308.0
DTH1_k127_3723029_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000001431 192.0
DTH1_k127_3723029_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000002402 155.0
DTH1_k127_3723029_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001028 79.0
DTH1_k127_3743873_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 591.0
DTH1_k127_3743873_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
DTH1_k127_3743873_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001047 262.0
DTH1_k127_3752929_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.503e-281 874.0
DTH1_k127_3752929_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 284.0
DTH1_k127_3752929_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000615 80.0
DTH1_k127_3759084_0 Tetratricopeptide repeat K02200 - - 0.00000000000000000000000000000000000000236 150.0
DTH1_k127_3759084_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000003326 100.0
DTH1_k127_3759084_2 Thioredoxin-like - - - 0.0005538 45.0
DTH1_k127_3778140_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1008.0
DTH1_k127_3778140_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
DTH1_k127_3778140_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 323.0
DTH1_k127_3778140_3 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000244 273.0
DTH1_k127_3778140_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
DTH1_k127_3778140_5 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000003396 226.0
DTH1_k127_3778140_6 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000004875 176.0
DTH1_k127_3778140_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000004456 77.0
DTH1_k127_3798856_0 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 464.0
DTH1_k127_3798856_1 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 464.0
DTH1_k127_3798856_2 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 311.0
DTH1_k127_3798856_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 295.0
DTH1_k127_3798856_4 FMN_bind K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000005272 249.0
DTH1_k127_3798893_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.693e-270 841.0
DTH1_k127_3798893_1 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
DTH1_k127_3798893_2 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.0000000001445 65.0
DTH1_k127_3798893_3 - - - - 0.00009733 46.0
DTH1_k127_3807095_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.955e-268 833.0
DTH1_k127_3807095_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 553.0
DTH1_k127_3807095_10 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000002986 50.0
DTH1_k127_3807095_2 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 399.0
DTH1_k127_3807095_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 391.0
DTH1_k127_3807095_4 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000008937 230.0
DTH1_k127_3807095_5 Cytochrome c oxidase assembly protein CtaG/Cox11 K02258 - - 0.000000000000000000000000000000000000000000000000000002425 198.0
DTH1_k127_3807095_6 signal sequence binding - - - 0.0000000000000000000000001242 118.0
DTH1_k127_3807095_7 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000002072 106.0
DTH1_k127_3807095_8 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000008489 109.0
DTH1_k127_3813654_0 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 376.0
DTH1_k127_3813654_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000151 181.0
DTH1_k127_3818963_0 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 449.0
DTH1_k127_3818963_1 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004727 279.0
DTH1_k127_3818963_2 MaoC like domain - - - 0.00000000000000000000000000000000000000001598 171.0
DTH1_k127_3832333_0 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 502.0
DTH1_k127_3832333_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002674 262.0
DTH1_k127_3832333_2 - - - - 0.00000000000000000000000000000000000000000000008272 178.0
DTH1_k127_3832333_4 Peptidase family M48 - - - 0.0000001332 55.0
DTH1_k127_3832333_5 - - - - 0.0000002214 57.0
DTH1_k127_3839596_0 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001607 227.0
DTH1_k127_3839596_1 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.00000000000000000000000000000000000000000000000000002068 207.0
DTH1_k127_3839596_2 LuxR family transcriptional regulator K13041 - - 0.000000000000006343 76.0
DTH1_k127_3852244_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 585.0
DTH1_k127_3852244_1 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
DTH1_k127_3855888_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 386.0
DTH1_k127_3855888_1 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
DTH1_k127_3855888_2 - - - - 0.000000000000000000000001386 106.0
DTH1_k127_3859228_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.301e-253 802.0
DTH1_k127_3859228_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
DTH1_k127_3859228_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000001335 212.0
DTH1_k127_3859228_3 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000001547 134.0
DTH1_k127_3859228_4 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000007527 118.0
DTH1_k127_3859228_5 NMT1-like family - - - 0.000002095 50.0
DTH1_k127_3900031_0 Enoyl-(Acyl carrier protein) reductase K00059,K00076 - 1.1.1.100,1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 313.0
DTH1_k127_3900031_1 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002973 248.0
DTH1_k127_3900031_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000874 226.0
DTH1_k127_3900031_3 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000002232 140.0
DTH1_k127_3900031_4 Belongs to the 'phage' integrase family - - - 0.00000000006531 63.0
DTH1_k127_3900031_5 Belongs to the 'phage' integrase family - - - 0.0002065 44.0
DTH1_k127_3912182_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1149.0
DTH1_k127_3912182_1 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000002217 199.0
DTH1_k127_3912182_2 DNA recombination-mediator protein A K04096 - - 0.00000000000006151 72.0
DTH1_k127_3924946_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.244e-213 669.0
DTH1_k127_3924946_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 311.0
DTH1_k127_3925661_0 Multicopper oxidase K22349 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 415.0
DTH1_k127_3942298_0 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 369.0
DTH1_k127_3942298_1 - - - - 0.0000000000000261 74.0
DTH1_k127_397116_0 Member of a two-component regulatory system K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 373.0
DTH1_k127_397116_1 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 313.0
DTH1_k127_397116_2 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 267.0
DTH1_k127_397116_3 - K09004 - - 0.000000000000000000000000000000000000000000000000000000000128 209.0
DTH1_k127_397116_4 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000007065 143.0
DTH1_k127_397116_5 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000001025 144.0
DTH1_k127_3971436_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 488.0
DTH1_k127_3971436_1 integrase recombinase Y4RB (NP_444040)) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000014 268.0
DTH1_k127_3975371_0 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
DTH1_k127_3975371_1 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000001946 220.0
DTH1_k127_3975371_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000003562 200.0
DTH1_k127_3975371_3 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000003377 157.0
DTH1_k127_3975371_4 n-acetyltransferase - - - 0.0000000000000006696 78.0
DTH1_k127_398715_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 357.0
DTH1_k127_4004739_0 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 436.0
DTH1_k127_4004739_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 356.0
DTH1_k127_4004739_2 TPM domain - - - 0.000000000000000000000000000000000000000000001204 167.0
DTH1_k127_4006643_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.887e-250 779.0
DTH1_k127_4006643_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 560.0
DTH1_k127_4006643_2 Protein of unknown function (DUF465) - - - 0.0000000000000005323 81.0
DTH1_k127_4007932_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 3.343e-292 908.0
DTH1_k127_4007932_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 516.0
DTH1_k127_4007932_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000001175 55.0
DTH1_k127_4040968_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 297.0
DTH1_k127_4040968_1 Polysaccharide biosynthesis protein K01710,K01784 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.46,5.1.3.2 0.000000000000000000000000000000001187 139.0
DTH1_k127_4040968_2 O-Antigen ligase K02847 - - 0.0000000174 56.0
DTH1_k127_4048406_0 extracellular solute-binding protein - - - 0.0 1028.0
DTH1_k127_4048406_1 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 598.0
DTH1_k127_4048406_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 520.0
DTH1_k127_4048406_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 427.0
DTH1_k127_4048406_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000009968 198.0
DTH1_k127_4048406_5 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000004612 124.0
DTH1_k127_4048406_6 - - - - 0.00000000004237 65.0
DTH1_k127_4063755_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 532.0
DTH1_k127_4063755_1 ATP synthase subunit C K02124 - - 0.00000000000000000000653 94.0
DTH1_k127_4072265_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 7.482e-229 712.0
DTH1_k127_4072265_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
DTH1_k127_4072265_2 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 313.0
DTH1_k127_4072265_3 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 303.0
DTH1_k127_4072265_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000001375 141.0
DTH1_k127_4072265_5 PFAM PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000001404 140.0
DTH1_k127_4075110_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 3.427e-194 617.0
DTH1_k127_4075110_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 513.0
DTH1_k127_4075110_2 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
DTH1_k127_4075110_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001631 276.0
DTH1_k127_4075110_4 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00003692 49.0
DTH1_k127_4079227_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 538.0
DTH1_k127_4079227_1 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.000000000000000000005684 95.0
DTH1_k127_4104789_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1709.0
DTH1_k127_4104789_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1154.0
DTH1_k127_4104789_10 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 402.0
DTH1_k127_4104789_11 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 391.0
DTH1_k127_4104789_12 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
DTH1_k127_4104789_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
DTH1_k127_4104789_14 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000001016 224.0
DTH1_k127_4104789_15 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000004977 211.0
DTH1_k127_4104789_16 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001362 212.0
DTH1_k127_4104789_17 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000007614 195.0
DTH1_k127_4104789_18 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000000002649 179.0
DTH1_k127_4104789_19 (FHA) domain - - - 0.000000000000000000000000000000000000000008289 154.0
DTH1_k127_4104789_2 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 5.47e-298 923.0
DTH1_k127_4104789_20 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000005587 151.0
DTH1_k127_4104789_21 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000007935 138.0
DTH1_k127_4104789_22 Rhodanese Homology Domain - - - 0.0000000000000000000000000006682 116.0
DTH1_k127_4104789_23 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000003328 110.0
DTH1_k127_4104789_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.913e-295 923.0
DTH1_k127_4104789_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 6.786e-221 734.0
DTH1_k127_4104789_5 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 588.0
DTH1_k127_4104789_6 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 508.0
DTH1_k127_4104789_7 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
DTH1_k127_4104789_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 450.0
DTH1_k127_4104789_9 SMART Elongator protein 3 MiaB NifB K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 421.0
DTH1_k127_411685_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 397.0
DTH1_k127_411685_1 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
DTH1_k127_411685_2 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000002152 226.0
DTH1_k127_411685_3 - - - - 0.00000000000000000000000000000000000000000000000000000001023 216.0
DTH1_k127_411685_4 - - - - 0.0000000000000000000000000000000000000000004344 169.0
DTH1_k127_411685_5 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000002291 128.0
DTH1_k127_411685_6 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000000000001823 113.0
DTH1_k127_411685_7 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000002257 102.0
DTH1_k127_411685_8 glycosyl - - - 0.00000000005155 66.0
DTH1_k127_4120580_0 Bacterial regulatory protein, Fis family K19641 - - 2.89e-211 670.0
DTH1_k127_4120580_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K00534 - 1.12.7.2 0.00000000000000000000000000000000000002299 145.0
DTH1_k127_4120580_2 Formyl transferase, C-terminal domain K19640 - - 0.0000000000000000000000001401 107.0
DTH1_k127_4130156_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 5.212e-219 683.0
DTH1_k127_4130156_1 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 584.0
DTH1_k127_4156298_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.42e-208 655.0
DTH1_k127_4156298_1 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 453.0
DTH1_k127_4156298_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000009402 183.0
DTH1_k127_4177084_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 557.0
DTH1_k127_4177084_1 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001024 264.0
DTH1_k127_4177084_10 Beta-lactamase - - - 0.00014 47.0
DTH1_k127_4177084_2 PFAM PemK family protein K07171 - - 0.000000000000000000000000000000000000000004182 160.0
DTH1_k127_4177084_3 - - - - 0.0000000000000000000000000000000000008742 141.0
DTH1_k127_4177084_4 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000002506 129.0
DTH1_k127_4177084_5 - - - - 0.000000000000000000000000000002832 123.0
DTH1_k127_4177084_6 Transcriptional regulator - - - 0.00000000000000008817 84.0
DTH1_k127_4177084_7 Transcriptional regulator antitoxin, MazE K07172 - - 0.00000000000002891 75.0
DTH1_k127_4177084_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000008283 72.0
DTH1_k127_4177084_9 - - - - 0.000002827 59.0
DTH1_k127_4177955_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1009.0
DTH1_k127_4177955_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.448e-281 871.0
DTH1_k127_4177955_10 Protein of unknown function (DUF3619) - - - 0.000000000008372 72.0
DTH1_k127_4177955_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 561.0
DTH1_k127_4177955_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 382.0
DTH1_k127_4177955_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
DTH1_k127_4177955_5 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002873 265.0
DTH1_k127_4177955_6 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000277 276.0
DTH1_k127_4177955_7 Protein of unknown function (DUF3106) - - - 0.00000000000000000000006107 109.0
DTH1_k127_4177955_8 Protein of unknown function (DUF2905) - - - 0.000000000000000000000099 99.0
DTH1_k127_4180766_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.227e-224 699.0
DTH1_k127_4193076_0 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 288.0
DTH1_k127_4193076_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000002016 246.0
DTH1_k127_4193076_2 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
DTH1_k127_4193076_3 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000007464 112.0
DTH1_k127_4193076_4 - - - - 0.0003457 48.0
DTH1_k127_4194005_0 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.175e-217 680.0
DTH1_k127_4194005_1 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 405.0
DTH1_k127_4204599_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0 1030.0
DTH1_k127_4204599_1 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.004e-219 687.0
DTH1_k127_4204599_2 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 336.0
DTH1_k127_4204599_3 membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 290.0
DTH1_k127_4230111_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567,K08356 - 1.20.2.1,1.20.9.1 0.0 1163.0
DTH1_k127_4230111_1 4Fe-4S dicluster domain K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 403.0
DTH1_k127_4230111_2 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.0000000000000000000000000000000007285 133.0
DTH1_k127_4230844_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1210.0
DTH1_k127_4257987_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 530.0
DTH1_k127_4257987_1 Polysaccharide deacetylase - - - 0.0000000000000000000004673 107.0
DTH1_k127_4265346_0 Heat shock 70 kDa protein K04043 - - 7.9e-322 994.0
DTH1_k127_4265346_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000007143 175.0
DTH1_k127_4285146_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 9.768e-232 750.0
DTH1_k127_4285146_1 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 488.0
DTH1_k127_4285146_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000000000003197 179.0
DTH1_k127_4285146_3 Nickel-dependent hydrogenase - - - 0.00000000000000005068 83.0
DTH1_k127_4320130_0 Cytochrome D1 heme domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 625.0
DTH1_k127_4320130_1 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 334.0
DTH1_k127_4320130_2 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000003215 172.0
DTH1_k127_4354697_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 413.0
DTH1_k127_4354697_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 396.0
DTH1_k127_4354697_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 377.0
DTH1_k127_4354697_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
DTH1_k127_4354697_4 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000295 278.0
DTH1_k127_4354697_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000003111 207.0
DTH1_k127_4392578_0 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 486.0
DTH1_k127_4401221_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1028.0
DTH1_k127_4401221_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.892e-253 789.0
DTH1_k127_4401221_10 Cytochrome c K08738 - - 0.00000000000000000000000000000214 125.0
DTH1_k127_4401221_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 434.0
DTH1_k127_4401221_3 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 422.0
DTH1_k127_4401221_4 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 426.0
DTH1_k127_4401221_5 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 375.0
DTH1_k127_4401221_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
DTH1_k127_4401221_7 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006667 269.0
DTH1_k127_4401221_8 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.0000000000000000000000000000000000000000000000000000000000001117 218.0
DTH1_k127_4401221_9 Cytochrome c K08738 - - 0.0000000000000000000000000000001125 132.0
DTH1_k127_4406309_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 389.0
DTH1_k127_4406309_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003925 280.0
DTH1_k127_4406309_2 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000001241 194.0
DTH1_k127_4406309_3 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000586 141.0
DTH1_k127_4406309_4 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000001403 136.0
DTH1_k127_4413815_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.596e-230 722.0
DTH1_k127_4413815_1 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 443.0
DTH1_k127_4413815_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006018 258.0
DTH1_k127_4413815_3 Bacterial transcriptional repressor - - - 0.00000003861 56.0
DTH1_k127_4417386_0 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
DTH1_k127_4417386_1 SpoIIAA-like - - - 0.00000000000000000000000000000000002158 138.0
DTH1_k127_4417386_2 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000008283 135.0
DTH1_k127_4430037_0 PFAM glycosyl transferase family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 344.0
DTH1_k127_4430037_1 Family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 329.0
DTH1_k127_4430037_2 epimerase dehydratase K08678 - 4.1.1.35 0.000001347 53.0
DTH1_k127_4480659_0 ribonuclease II K01147 - 3.1.13.1 3.146e-200 634.0
DTH1_k127_4480659_1 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 319.0
DTH1_k127_4480659_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
DTH1_k127_4509116_0 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 367.0
DTH1_k127_4509116_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000002521 220.0
DTH1_k127_4509116_2 Divalent cation transporter K06213 - - 0.000000000000000000000000000000000000000000000000000005404 195.0
DTH1_k127_4523865_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.458e-278 868.0
DTH1_k127_4523865_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.049e-267 829.0
DTH1_k127_4523865_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.488e-207 653.0
DTH1_k127_4523865_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.881e-196 616.0
DTH1_k127_4523865_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 391.0
DTH1_k127_4523865_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
DTH1_k127_4527031_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.83e-253 784.0
DTH1_k127_4527031_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.101e-235 744.0
DTH1_k127_4527031_2 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 528.0
DTH1_k127_4527031_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
DTH1_k127_4527031_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
DTH1_k127_4527031_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001028 242.0
DTH1_k127_4528846_0 Molecular chaperone. Has ATPase activity K04079 - - 6.443e-293 913.0
DTH1_k127_4528846_1 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 306.0
DTH1_k127_4534380_0 ABC transporter transmembrane region K06147 - - 2.927e-303 938.0
DTH1_k127_4534380_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.958e-244 762.0
DTH1_k127_4534380_2 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 606.0
DTH1_k127_4534380_3 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
DTH1_k127_4534380_4 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 352.0
DTH1_k127_4534380_5 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 346.0
DTH1_k127_4534380_6 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 327.0
DTH1_k127_4534380_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
DTH1_k127_4534380_8 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 307.0
DTH1_k127_4534380_9 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000006976 194.0
DTH1_k127_4538471_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 610.0
DTH1_k127_4538471_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 509.0
DTH1_k127_4538471_2 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 354.0
DTH1_k127_4538471_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000055 292.0
DTH1_k127_4538471_4 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004964 242.0
DTH1_k127_4538471_5 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000004911 192.0
DTH1_k127_4538471_6 MazG-like family - - - 0.0000000000000000000000000000000005465 132.0
DTH1_k127_4538471_7 Protein of unknown function (DUF465) K09794 - - 0.000000006148 63.0
DTH1_k127_4551318_0 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 518.0
DTH1_k127_4551318_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009079 279.0
DTH1_k127_4551318_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000008843 53.0
DTH1_k127_4552393_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1667.0
DTH1_k127_4552393_1 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 395.0
DTH1_k127_4552393_2 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 349.0
DTH1_k127_4552393_3 Chaperone protein TorD - - - 0.00000000000000000000000000000000000000001468 158.0
DTH1_k127_4552393_4 - - - - 0.00000000000000003218 84.0
DTH1_k127_4552393_5 - - - - 0.00000000003358 73.0
DTH1_k127_4556444_0 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 323.0
DTH1_k127_4556444_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
DTH1_k127_4556444_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000003317 92.0
DTH1_k127_4643775_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.282e-292 910.0
DTH1_k127_4643775_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000001178 123.0
DTH1_k127_4643775_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00002812 46.0
DTH1_k127_4654767_0 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 481.0
DTH1_k127_4654767_1 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 376.0
DTH1_k127_4654767_2 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 379.0
DTH1_k127_4660575_0 NADPH-dependent glutamate synthase beta - - - 3.999e-306 949.0
DTH1_k127_4660575_1 Fe-S oxidoreductase K21834 - - 1.152e-267 829.0
DTH1_k127_4660575_10 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000002056 201.0
DTH1_k127_4660575_11 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000000000000000000000000000003575 215.0
DTH1_k127_4660575_12 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000001111 188.0
DTH1_k127_4660575_13 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000000005865 188.0
DTH1_k127_4660575_14 DsrC like protein - - - 0.000000000000000000000000000000000000000000007216 164.0
DTH1_k127_4660575_15 DsrH like protein K07237 - - 0.000000000000000000000000000000388 125.0
DTH1_k127_4660575_16 - - - - 0.000000000000000000000000004002 115.0
DTH1_k127_4660575_17 - - - - 0.00000000000000000000001008 102.0
DTH1_k127_4660575_2 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.099e-219 687.0
DTH1_k127_4660575_3 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 1.696e-217 677.0
DTH1_k127_4660575_4 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 501.0
DTH1_k127_4660575_5 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 349.0
DTH1_k127_4660575_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 350.0
DTH1_k127_4660575_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 354.0
DTH1_k127_4660575_8 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000000000000001699 214.0
DTH1_k127_4660575_9 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
DTH1_k127_469337_0 Nitronate monooxygenase K00459 - 1.13.12.16 6.932e-224 701.0
DTH1_k127_469337_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 563.0
DTH1_k127_469337_2 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
DTH1_k127_469337_3 - - - - 0.0000000005677 65.0
DTH1_k127_469337_4 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0006269 47.0
DTH1_k127_4694237_0 Sulfate transporter antisigma-factor antagonist STAS - - - 6.065e-299 932.0
DTH1_k127_4694237_1 STAS domain K03321 - - 1.505e-231 733.0
DTH1_k127_4694237_2 Chromate K07240 - - 5.172e-200 636.0
DTH1_k127_4694237_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 559.0
DTH1_k127_4694237_4 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 323.0
DTH1_k127_4694237_5 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 296.0
DTH1_k127_4694237_6 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000000000000000000000000000002384 201.0
DTH1_k127_4694237_7 Ethylbenzene dehydrogenase - - - 0.000000000000000000002683 105.0
DTH1_k127_4694237_8 Carboxymuconolactone decarboxylase family - - - 0.000000000000162 71.0
DTH1_k127_4694237_9 Protein tyrosine kinase - - - 0.0001681 52.0
DTH1_k127_4694252_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 353.0
DTH1_k127_4694252_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 323.0
DTH1_k127_4694252_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005815 254.0
DTH1_k127_4694252_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009855 243.0
DTH1_k127_4694252_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000000000006312 131.0
DTH1_k127_4694252_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001028 79.0
DTH1_k127_4694252_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000003656 73.0
DTH1_k127_4694252_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000002438 49.0
DTH1_k127_4751824_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 540.0
DTH1_k127_4751824_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
DTH1_k127_4751824_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
DTH1_k127_4751824_3 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000000002158 135.0
DTH1_k127_4764109_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.981e-274 847.0
DTH1_k127_4764109_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 388.0
DTH1_k127_4764109_2 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 337.0
DTH1_k127_4764109_3 Cbb3-type cytochrome oxidase K00407 - - 0.00000000001071 69.0
DTH1_k127_4765321_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.077e-224 699.0
DTH1_k127_4765321_1 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 355.0
DTH1_k127_4765321_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 333.0
DTH1_k127_4765321_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000107 285.0
DTH1_k127_4765321_4 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 283.0
DTH1_k127_4765321_5 stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000003594 164.0
DTH1_k127_4765321_6 NGG1p interacting factor 3 - - - 0.000000000000000000000000003678 111.0
DTH1_k127_4775483_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 511.0
DTH1_k127_4775483_1 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000006329 124.0
DTH1_k127_4775483_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00001102 49.0
DTH1_k127_4787499_0 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001995 278.0
DTH1_k127_4787499_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001291 237.0
DTH1_k127_4787499_2 HPP family K07168 - - 0.000000001435 59.0
DTH1_k127_4797217_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1420.0
DTH1_k127_4797217_1 FecR protein - - - 0.000003045 57.0
DTH1_k127_4803797_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1065.0
DTH1_k127_4803797_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 567.0
DTH1_k127_4803797_2 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 515.0
DTH1_k127_4803797_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
DTH1_k127_4803797_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
DTH1_k127_4803797_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000006447 197.0
DTH1_k127_4803797_6 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000003145 167.0
DTH1_k127_4803797_7 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000002592 127.0
DTH1_k127_4803797_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000006835 94.0
DTH1_k127_4811691_0 argininosuccinate lyase K01755 - 4.3.2.1 2.683e-229 718.0
DTH1_k127_4811691_1 Histidine kinase K08082 - 2.7.13.3 0.000000001796 62.0
DTH1_k127_4819634_0 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 472.0
DTH1_k127_4819634_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 361.0
DTH1_k127_4819634_2 Protein of unknown function DUF72 - - - 0.0000000002832 64.0
DTH1_k127_4822952_0 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003889 243.0
DTH1_k127_4822952_1 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
DTH1_k127_4822952_2 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000009769 133.0
DTH1_k127_4822952_3 Helix-turn-helix K21498 - - 0.00000000000000000000000000003528 119.0
DTH1_k127_4822952_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000005334 115.0
DTH1_k127_4822952_5 Rubredoxin - - - 0.00000000000000000000002218 109.0
DTH1_k127_4822952_6 Hydrogenase-1 expression protein HyaE - - - 0.000000000000000000001898 109.0
DTH1_k127_4822952_7 Ni,Fe-hydrogenase I large subunit - - - 0.00000000000000229 83.0
DTH1_k127_4828076_0 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 456.0
DTH1_k127_4828076_1 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 315.0
DTH1_k127_4828076_2 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000003421 175.0
DTH1_k127_4828076_3 - - - - 0.0000000000000000000000000000000000000007986 154.0
DTH1_k127_4872691_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 9.649e-216 674.0
DTH1_k127_4872691_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 431.0
DTH1_k127_4872691_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 342.0
DTH1_k127_4872691_3 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
DTH1_k127_4872691_4 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007832 250.0
DTH1_k127_4872691_5 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000279 245.0
DTH1_k127_4872691_6 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000000000001597 219.0
DTH1_k127_4872691_7 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000003263 188.0
DTH1_k127_4872691_8 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000008477 111.0
DTH1_k127_4875486_0 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 409.0
DTH1_k127_4875486_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 391.0
DTH1_k127_4875486_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000001281 147.0
DTH1_k127_4875822_0 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
DTH1_k127_4875822_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
DTH1_k127_4875822_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
DTH1_k127_4875822_3 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000001142 203.0
DTH1_k127_4875822_4 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000000005727 186.0
DTH1_k127_4875822_5 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000009941 153.0
DTH1_k127_4875822_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000008355 119.0
DTH1_k127_4875822_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000004797 107.0
DTH1_k127_4876706_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.483e-261 812.0
DTH1_k127_4876706_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.55e-226 721.0
DTH1_k127_4876706_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 409.0
DTH1_k127_4876706_3 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000004232 211.0
DTH1_k127_4876706_4 protein conserved in bacteria K03690 - - 0.000000000000000000000000000000000000000009206 165.0
DTH1_k127_4876706_5 Tim44 - - - 0.0000000000000000000000000000000000004615 142.0
DTH1_k127_4876706_6 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000442 127.0
DTH1_k127_4876706_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000003093 78.0
DTH1_k127_4891835_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 546.0
DTH1_k127_4891835_1 D-amino acid dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004442 260.0
DTH1_k127_4899141_0 TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA K03694 - - 0.0 1179.0
DTH1_k127_4899141_1 sulfide dehydrogenase K05301 - 1.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 514.0
DTH1_k127_4899141_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 329.0
DTH1_k127_4899141_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
DTH1_k127_4899141_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000002813 199.0
DTH1_k127_4899141_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000005339 162.0
DTH1_k127_4899141_6 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000005352 149.0
DTH1_k127_4899141_7 cytochrome - - - 0.0000000000000002858 83.0
DTH1_k127_4907052_0 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 313.0
DTH1_k127_4907052_1 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 312.0
DTH1_k127_4912289_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 3.01e-245 763.0
DTH1_k127_4912289_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000002217 150.0
DTH1_k127_4918484_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 578.0
DTH1_k127_4918484_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000001746 209.0
DTH1_k127_4918484_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000004081 113.0
DTH1_k127_4927319_0 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 582.0
DTH1_k127_4927319_1 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 467.0
DTH1_k127_4927319_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 447.0
DTH1_k127_4927319_3 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 429.0
DTH1_k127_4927319_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 306.0
DTH1_k127_4927319_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000005469 230.0
DTH1_k127_4927319_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0000000000000000000001112 108.0
DTH1_k127_4939858_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 477.0
DTH1_k127_4939858_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 253.0
DTH1_k127_4939858_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000008188 135.0
DTH1_k127_4958067_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1190.0
DTH1_k127_4958067_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 419.0
DTH1_k127_4958067_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 367.0
DTH1_k127_4958067_3 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.00000000000000000000000000000000000000006685 160.0
DTH1_k127_4958067_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000007685 133.0
DTH1_k127_4967978_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 7.706e-270 834.0
DTH1_k127_4967978_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.263e-213 671.0
DTH1_k127_4967978_2 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 443.0
DTH1_k127_4967978_3 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 388.0
DTH1_k127_4967978_4 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000005507 153.0
DTH1_k127_4975556_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 5.42e-242 756.0
DTH1_k127_4975556_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000007253 235.0
DTH1_k127_4975556_2 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000001613 207.0
DTH1_k127_4975556_3 protein conserved in bacteria K09806 - - 0.000000000000000000000002086 105.0
DTH1_k127_4976206_0 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000004849 255.0
DTH1_k127_4976206_1 VIT family - - - 0.0000000000000000000000000000000000000001517 159.0
DTH1_k127_4976914_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1327.0
DTH1_k127_4976914_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000001959 127.0
DTH1_k127_4976994_0 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 265.0
DTH1_k127_4976994_1 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000000000000001756 237.0
DTH1_k127_4976994_2 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003369 216.0
DTH1_k127_4976994_3 Glycine zipper 2TM domain - - - 0.00000005296 59.0
DTH1_k127_5021588_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.249e-290 897.0
DTH1_k127_5021588_1 SMART CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 616.0
DTH1_k127_5021588_2 response regulator K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 332.0
DTH1_k127_5021588_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000007351 169.0
DTH1_k127_5021588_4 Redoxin domain protein - - - 0.000000000000000000000000000000000000002466 150.0
DTH1_k127_5021588_5 PFAM HAMP domain, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, His Kinase A (phosphoacceptor) domain, Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.0000000000000000000000002042 110.0
DTH1_k127_5039660_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.0 1022.0
DTH1_k127_5039660_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 251.0
DTH1_k127_5039660_2 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000008667 190.0
DTH1_k127_5039660_3 - - - - 0.000000000000000000000000002712 119.0
DTH1_k127_5039660_4 YMGG-like Gly-zipper - - - 0.0000000000000000001782 89.0
DTH1_k127_5046379_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 570.0
DTH1_k127_5046379_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 532.0
DTH1_k127_5046379_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008647 271.0
DTH1_k127_5046379_3 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
DTH1_k127_5046379_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000009129 127.0
DTH1_k127_5046379_5 Thioredoxin domain - - - 0.000000000000000000000000522 106.0
DTH1_k127_5046379_6 4Fe-4S dicluster domain - - - 0.0000000000000006547 83.0
DTH1_k127_5064301_0 serine threonine protein kinase K12132 - 2.7.11.1 2.041e-262 821.0
DTH1_k127_5064301_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 360.0
DTH1_k127_5064301_2 (FHA) domain - - - 0.000000000000000000000000000000000000000000000001265 176.0
DTH1_k127_507211_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.105e-251 782.0
DTH1_k127_507211_1 Belongs to the GARS family K01945 - 6.3.4.13 1.86e-204 644.0
DTH1_k127_507211_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 543.0
DTH1_k127_507211_3 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000001235 123.0
DTH1_k127_507211_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000001586 117.0
DTH1_k127_5076736_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 378.0
DTH1_k127_5076736_1 Methyl-transferase K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002486 283.0
DTH1_k127_5076736_2 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000005582 196.0
DTH1_k127_5077390_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.322e-286 893.0
DTH1_k127_5077390_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 406.0
DTH1_k127_5077390_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 349.0
DTH1_k127_5077390_3 4Fe-4S ferredoxin K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 331.0
DTH1_k127_5077390_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 261.0
DTH1_k127_5077390_5 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001169 248.0
DTH1_k127_5077390_6 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002583 224.0
DTH1_k127_5077390_7 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000004014 210.0
DTH1_k127_5081714_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.295e-238 747.0
DTH1_k127_5086090_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 521.0
DTH1_k127_5086090_1 dihydroorotase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 353.0
DTH1_k127_5086973_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 4.951e-310 957.0
DTH1_k127_5086973_1 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 297.0
DTH1_k127_5091289_0 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 454.0
DTH1_k127_5091289_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 410.0
DTH1_k127_5091289_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
DTH1_k127_5091289_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 383.0
DTH1_k127_5091289_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
DTH1_k127_5091289_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000002256 262.0
DTH1_k127_509189_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 501.0
DTH1_k127_509189_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 503.0
DTH1_k127_509189_2 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000008703 117.0
DTH1_k127_509189_3 Phosphoribosyl transferase domain - - - 0.00004851 50.0
DTH1_k127_5103542_0 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 604.0
DTH1_k127_5103542_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 351.0
DTH1_k127_5119038_0 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000000000009813 180.0
DTH1_k127_5119038_1 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000000146 177.0
DTH1_k127_5119038_2 Uncharacterised protein family (UPF0149) K07039 - - 0.00000000000000000000000000000000000000000000003625 188.0
DTH1_k127_5119038_3 UvrD-like helicase C-terminal domain - - - 0.00000000000000000000000000000000000000001204 156.0
DTH1_k127_5119038_4 Alg9-like mannosyltransferase family K05286 - - 0.0000000001689 74.0
DTH1_k127_5129019_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1131.0
DTH1_k127_5155131_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 543.0
DTH1_k127_5155131_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 525.0
DTH1_k127_5160505_0 8 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 341.0
DTH1_k127_5160505_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008311 283.0
DTH1_k127_5184723_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 323.0
DTH1_k127_5184723_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 302.0
DTH1_k127_5184723_2 carboxylase K01965 - 6.4.1.3 0.0000000000000000000004725 95.0
DTH1_k127_5193858_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.062e-206 662.0
DTH1_k127_5193858_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000004274 209.0
DTH1_k127_5193858_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000001206 203.0
DTH1_k127_5198820_0 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 8.784e-309 952.0
DTH1_k127_5198820_1 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 451.0
DTH1_k127_5198820_2 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 391.0
DTH1_k127_5198820_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
DTH1_k127_5198820_4 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 281.0
DTH1_k127_5198820_5 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006899 276.0
DTH1_k127_5198820_6 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000001025 144.0
DTH1_k127_5213304_0 response regulator receiver K13041 - - 0.00000000000000000000000000000000000000000000000000000000001692 218.0
DTH1_k127_5213304_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000001491 130.0
DTH1_k127_5213304_2 Planctomycete cytochrome C - - - 0.0000000000000000000000002839 111.0
DTH1_k127_5213419_0 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 337.0
DTH1_k127_5213419_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000005063 190.0
DTH1_k127_5213419_2 SpoIIAA-like - - - 0.0000000000000000000000000000000000003971 153.0
DTH1_k127_5213419_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000003137 101.0
DTH1_k127_5213419_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000415 51.0
DTH1_k127_5230079_0 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 427.0
DTH1_k127_5230079_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 328.0
DTH1_k127_5230079_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000007928 183.0
DTH1_k127_5230079_3 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000001041 185.0
DTH1_k127_5240955_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 552.0
DTH1_k127_5240955_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 313.0
DTH1_k127_5240955_2 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000005588 247.0
DTH1_k127_5241051_0 Signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005736 243.0
DTH1_k127_5241051_1 PFAM response regulator receiver K15012 - - 0.00000000000000000000000000000000000000000000000000000000000001608 230.0
DTH1_k127_5241051_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000009484 114.0
DTH1_k127_5253480_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 573.0
DTH1_k127_5253480_1 - - - - 0.00000000000000000000000000000000000000000000000000000000002511 231.0
DTH1_k127_5253480_2 Wzy family polymerase, exosortase system type 1 associated - - - 0.00000000000000000000005921 101.0
DTH1_k127_5253895_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.248e-300 934.0
DTH1_k127_52597_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 2.964e-245 773.0
DTH1_k127_52597_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 523.0
DTH1_k127_52597_2 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 460.0
DTH1_k127_52597_3 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 283.0
DTH1_k127_52597_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000006003 215.0
DTH1_k127_52597_5 FtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000002487 207.0
DTH1_k127_52597_6 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000002081 203.0
DTH1_k127_52597_7 Small MutS-related domain - - - 0.0000000000000000000000000000000000000000000000000007094 189.0
DTH1_k127_5262092_0 Putative beta-barrel porin 2 - - - 0.00000000000000000000000000000000000000000000000000000004494 214.0
DTH1_k127_5262092_1 - - - - 0.00000000000001735 85.0
DTH1_k127_5272693_0 PFAM ABC-1 domain protein K03688 - - 2.408e-245 768.0
DTH1_k127_5272693_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000006046 211.0
DTH1_k127_5272693_2 - - - - 0.000000000000000000000000000000000000000000000000000005079 197.0
DTH1_k127_5272693_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000002222 184.0
DTH1_k127_5307747_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 397.0
DTH1_k127_5307747_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000174 234.0
DTH1_k127_5307747_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000001021 183.0
DTH1_k127_5307747_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.00000000000274 68.0
DTH1_k127_5320845_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 524.0
DTH1_k127_5320845_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 531.0
DTH1_k127_5320845_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 356.0
DTH1_k127_5320845_3 PIN domain K07065 - - 0.0000000000000000000000000000000001078 137.0
DTH1_k127_5320845_4 Glycosyl transferases group 1 K03208 - - 0.00000000007634 64.0
DTH1_k127_5326875_0 DNA polymerase X family K02347 - - 1.544e-256 802.0
DTH1_k127_5326875_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 360.0
DTH1_k127_5326875_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000005802 143.0
DTH1_k127_5326875_3 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000003634 152.0
DTH1_k127_5332307_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 3.989e-209 679.0
DTH1_k127_5332307_1 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
DTH1_k127_5403968_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 569.0
DTH1_k127_5403968_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 555.0
DTH1_k127_5403968_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 517.0
DTH1_k127_5403968_3 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 273.0
DTH1_k127_5403968_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
DTH1_k127_5403968_5 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
DTH1_k127_5403968_6 PFAM Rieske 2Fe-2S K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000001113 173.0
DTH1_k127_5403968_7 Protein of unknown function (DUF2788) - - - 0.000000000000000000000006778 102.0
DTH1_k127_5403968_8 - - - - 0.0000004668 61.0
DTH1_k127_5458399_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1748.0
DTH1_k127_5458399_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008589 260.0
DTH1_k127_5458399_2 Domain of unknown function (DUF4149) - - - 0.00000000000003585 74.0
DTH1_k127_5467885_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.792e-319 991.0
DTH1_k127_5467885_1 AAA ATPase central domain protein K07478 - - 7.741e-221 691.0
DTH1_k127_5467885_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.254e-209 657.0
DTH1_k127_5467885_3 Helix-turn-helix type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 403.0
DTH1_k127_5467885_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
DTH1_k127_5476387_0 Pfam Fatty acid - - - 0.0 1065.0
DTH1_k127_5476387_1 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 433.0
DTH1_k127_5476387_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 362.0
DTH1_k127_5476387_3 glycosyl transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 327.0
DTH1_k127_5476387_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 269.0
DTH1_k127_5476387_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000002141 208.0
DTH1_k127_5476387_6 - - - - 0.000000000000000000000000000000000001264 150.0
DTH1_k127_5476387_7 DNA repair photolyase - - - 0.0002356 43.0
DTH1_k127_5482153_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 348.0
DTH1_k127_5482153_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000003104 230.0
DTH1_k127_5482153_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000001478 87.0
DTH1_k127_548311_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 511.0
DTH1_k127_548311_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 499.0
DTH1_k127_548311_2 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 362.0
DTH1_k127_548311_3 Protein conserved in bacteria - - - 0.00000006065 59.0
DTH1_k127_5497265_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 5.754e-224 698.0
DTH1_k127_5497265_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000001158 233.0
DTH1_k127_5497265_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000001212 59.0
DTH1_k127_5500798_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 9.927e-209 655.0
DTH1_k127_5500798_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 533.0
DTH1_k127_5500798_2 Histidine kinase K07637 - 2.7.13.3 0.00000000000000000001367 92.0
DTH1_k127_550283_0 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 420.0
DTH1_k127_550283_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 299.0
DTH1_k127_550283_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000001477 226.0
DTH1_k127_550283_3 TIGRFAM phasin family protein - - - 0.000000000000000000000000000000007399 132.0
DTH1_k127_5526116_0 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001047 267.0
DTH1_k127_5526116_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000001057 237.0
DTH1_k127_5526116_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000401 187.0
DTH1_k127_5526116_3 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000000000008028 167.0
DTH1_k127_5526116_4 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000004707 172.0
DTH1_k127_5526116_5 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.0000000000000000000000000000000000000000005108 160.0
DTH1_k127_5526116_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000002 70.0
DTH1_k127_5526259_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 9.589e-273 848.0
DTH1_k127_5526259_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 615.0
DTH1_k127_5526259_2 dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 306.0
DTH1_k127_5526259_3 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000004397 150.0
DTH1_k127_5526259_4 periplasmic protein - - - 0.00000000000000000009006 101.0
DTH1_k127_5545027_0 protein synthesis factor, GTP-binding K06207 - - 7.241e-308 952.0
DTH1_k127_5545027_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000452 228.0
DTH1_k127_5548095_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1170.0
DTH1_k127_5549815_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 501.0
DTH1_k127_5549815_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 464.0
DTH1_k127_5549815_2 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 404.0
DTH1_k127_5549815_3 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 384.0
DTH1_k127_5549815_4 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 347.0
DTH1_k127_5549815_5 17 kDa surface antigen - - - 0.0000000000000000000000000000000004826 140.0
DTH1_k127_5549815_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000122 121.0
DTH1_k127_5549815_7 - - - - 0.00000000000000000000005491 105.0
DTH1_k127_5549815_8 - - - - 0.000000000000000000008024 105.0
DTH1_k127_5571930_0 Nuclease-related domain - - - 8.677e-194 614.0
DTH1_k127_5606791_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.258e-254 792.0
DTH1_k127_5606791_1 Permease MlaE K02066 - - 0.0004643 49.0
DTH1_k127_5613381_0 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 502.0
DTH1_k127_5613381_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000007427 210.0
DTH1_k127_5613381_2 DNA mismatch repair protein, C-terminal domain K03572 - - 0.00000000000000000000000000000000000000002643 154.0
DTH1_k127_5613381_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.00000000000000000000000000000000000002224 145.0
DTH1_k127_5616251_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000001043 154.0
DTH1_k127_5616251_1 PIN domain - - - 0.000000000000000000000000000000000005473 145.0
DTH1_k127_5620242_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 440.0
DTH1_k127_5620242_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000002025 197.0
DTH1_k127_5642011_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 429.0
DTH1_k127_5642011_1 Putative ATP-dependent DNA helicase recG C-terminal - - - 0.000000000000000000009116 96.0
DTH1_k127_5668574_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 533.0
DTH1_k127_5668574_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000002682 138.0
DTH1_k127_5668574_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000001453 97.0
DTH1_k127_5699624_0 Domain of unknown function (DUF4091) - - - 0.0002769 53.0
DTH1_k127_5727783_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 467.0
DTH1_k127_5727783_1 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 405.0
DTH1_k127_5727783_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 353.0
DTH1_k127_5727783_3 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004552 299.0
DTH1_k127_5727783_4 TIR domain - - - 0.000000000000000000000000000003111 139.0
DTH1_k127_5727783_5 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.000000000000002244 79.0
DTH1_k127_5735903_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 287.0
DTH1_k127_5735903_1 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000000000000000000000004636 170.0
DTH1_k127_5735903_2 - - - - 0.0004021 47.0
DTH1_k127_5758239_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1226.0
DTH1_k127_5758239_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.594e-294 914.0
DTH1_k127_5758239_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 356.0
DTH1_k127_5758239_3 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 334.0
DTH1_k127_5758239_4 regulatory protein Crp K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002827 265.0
DTH1_k127_5758239_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000176 69.0
DTH1_k127_5769604_0 Esterase, phb depolymerase family - - - 0.0000000000000000000000000000000001432 135.0
DTH1_k127_5769604_2 - - - - 0.0000000000003138 81.0
DTH1_k127_5780485_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 316.0
DTH1_k127_5780485_1 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000001406 191.0
DTH1_k127_5788794_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 415.0
DTH1_k127_5788794_1 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000000000000000000000000000000000000000000002416 216.0
DTH1_k127_5788794_2 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.000000006488 68.0
DTH1_k127_5788794_3 - - - - 0.0000001141 58.0
DTH1_k127_5790708_0 Insecticidal toxin complex protein TcaC - - - 4.216e-262 869.0
DTH1_k127_5790708_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.701e-220 688.0
DTH1_k127_5790708_2 - - - - 0.00000001134 64.0
DTH1_k127_5795467_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 413.0
DTH1_k127_5795467_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000227 237.0
DTH1_k127_5795467_2 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000009928 203.0
DTH1_k127_5795467_3 DUF218 domain - - - 0.00000000000000000000000000000000000000000001409 169.0
DTH1_k127_5807116_0 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 429.0
DTH1_k127_5807116_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000002787 202.0
DTH1_k127_5807116_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000627 87.0
DTH1_k127_5809514_0 GMP synthase C terminal domain K01951 - 6.3.5.2 7.168e-299 921.0
DTH1_k127_5809514_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.986e-249 777.0
DTH1_k127_5809514_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000001149 148.0
DTH1_k127_5809514_3 Domain of unknown function (DUF4124) - - - 0.0000000000000007687 85.0
DTH1_k127_5811830_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 423.0
DTH1_k127_5811830_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
DTH1_k127_5811830_2 Pfam Fatty acid - - - 0.000000000000000000000000000000000000000000000000000000000004744 211.0
DTH1_k127_5811830_3 ABC transporter K15738 - - 0.000000000000000000000000000000000000000000000000000000006734 201.0
DTH1_k127_5811830_4 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000002582 158.0
DTH1_k127_58387_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.491e-312 969.0
DTH1_k127_5842879_0 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
DTH1_k127_5842879_1 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000001462 221.0
DTH1_k127_5895718_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 5.472e-282 882.0
DTH1_k127_5895718_1 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 344.0
DTH1_k127_5917310_0 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 481.0
DTH1_k127_5917310_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 456.0
DTH1_k127_5917310_2 PLD-like domain - - - 0.00000000000000000000000000000003845 127.0
DTH1_k127_5918212_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 306.0
DTH1_k127_5918212_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 293.0
DTH1_k127_5918212_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000004014 237.0
DTH1_k127_5918552_0 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 368.0
DTH1_k127_5918552_1 - - - - 0.00000000000000000000009738 108.0
DTH1_k127_5921102_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.001e-204 643.0
DTH1_k127_5921102_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
DTH1_k127_5921102_2 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000001271 258.0
DTH1_k127_5921102_3 Rhodanese Homology Domain - - - 0.00000000000000000000000007909 110.0
DTH1_k127_5923218_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 449.0
DTH1_k127_5923218_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 329.0
DTH1_k127_5923877_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 479.0
DTH1_k127_5923877_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 359.0
DTH1_k127_5931853_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 539.0
DTH1_k127_5931853_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 472.0
DTH1_k127_5958085_0 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001369 246.0
DTH1_k127_5958085_1 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000000006078 220.0
DTH1_k127_5968300_0 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000787 200.0
DTH1_k127_5968300_1 anaerobic respiration - - - 0.00000000000000000000000000000000000000000004778 170.0
DTH1_k127_5968300_2 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.000000000000000000000000000007825 130.0
DTH1_k127_5974207_0 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 542.0
DTH1_k127_5974207_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 297.0
DTH1_k127_5984452_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.677e-227 717.0
DTH1_k127_5984452_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0003507 45.0
DTH1_k127_6013165_0 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
DTH1_k127_6013165_1 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 331.0
DTH1_k127_6013165_2 Binding-protein-dependent transport system inner membrane component K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 319.0
DTH1_k127_6013165_3 PFAM ABC transporter related K10004 - - 0.0000000000000000000000000000000000000001373 163.0
DTH1_k127_6013165_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000532 130.0
DTH1_k127_6025329_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1120.0
DTH1_k127_6025329_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 610.0
DTH1_k127_6025329_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000199 205.0
DTH1_k127_6025329_3 Membrane-bound serine protease (ClpP class) K07403 - - 0.0007338 47.0
DTH1_k127_6069788_0 Sulfatase K01130 - 3.1.6.1 0.0 1435.0
DTH1_k127_6069788_1 Sulfatase K01130 - 3.1.6.1 0.0 1394.0
DTH1_k127_6069788_10 Ion channel - - - 0.0000000000000002405 88.0
DTH1_k127_6069788_2 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 302.0
DTH1_k127_6069788_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006255 238.0
DTH1_k127_6069788_4 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000002719 228.0
DTH1_k127_6069788_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000002009 192.0
DTH1_k127_6069788_6 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000007065 169.0
DTH1_k127_6069788_7 - - - - 0.000000000000000000000000000000000000000001338 172.0
DTH1_k127_6069788_8 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000008561 132.0
DTH1_k127_6069788_9 - - - - 0.00000000000000000000000000001799 121.0
DTH1_k127_6118781_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1005.0
DTH1_k127_6118781_1 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000008714 206.0
DTH1_k127_6118781_2 Pfam Glutaredoxin - - - 0.0000000000000000000000000000005458 142.0
DTH1_k127_6148809_0 chemotaxis K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 537.0
DTH1_k127_6148809_1 PFAM CheW domain protein K02659 - - 0.000000000000000000000000000000000000006295 149.0
DTH1_k127_6148809_2 Histidine kinase K02487,K06596 - - 0.000000000000000000000000000003179 125.0
DTH1_k127_6149590_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 311.0
DTH1_k127_6149590_1 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000006307 144.0
DTH1_k127_6149590_2 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000625 108.0
DTH1_k127_6167549_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 5.002e-206 649.0
DTH1_k127_6167549_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 330.0
DTH1_k127_6167549_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
DTH1_k127_6167549_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000011 142.0
DTH1_k127_6170172_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.593e-271 848.0
DTH1_k127_6170172_1 Isocitrate lyase K01637 - 4.1.3.1 2.388e-249 775.0
DTH1_k127_6170172_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.553e-228 712.0
DTH1_k127_6170172_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 238.0
DTH1_k127_6194064_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 482.0
DTH1_k127_6194064_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 411.0
DTH1_k127_6194064_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001463 280.0
DTH1_k127_6201598_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 411.0
DTH1_k127_6201598_1 blue (type 1) copper - - - 0.0000000000000000000000000000001629 128.0
DTH1_k127_6201598_2 negative regulation of establishment of protein localization K02570 - - 0.000000000000000001812 89.0
DTH1_k127_6224896_0 Magnesium transport protein CorA - - - 3.854e-229 721.0
DTH1_k127_6224896_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001688 283.0
DTH1_k127_6224896_2 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003823 269.0
DTH1_k127_6227679_0 SNARE associated Golgi protein - - - 0.0 1042.0
DTH1_k127_6227679_1 PFAM ABC transporter K06158 - - 2.673e-223 706.0
DTH1_k127_6227679_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 561.0
DTH1_k127_6227679_3 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 446.0
DTH1_k127_6227679_4 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 326.0
DTH1_k127_6228741_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 3.528e-219 690.0
DTH1_k127_6228741_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004148 295.0
DTH1_k127_6228741_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
DTH1_k127_6228741_3 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000833 249.0
DTH1_k127_6228741_4 Trypsin K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000001026 158.0
DTH1_k127_6228741_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000005514 171.0
DTH1_k127_6228741_6 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000001169 131.0
DTH1_k127_6228741_7 Protein of unknown function (DUF3460) - - - 0.0000000000003698 73.0
DTH1_k127_6249480_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 320.0
DTH1_k127_6249480_1 Glycosyl transferase family 41 - - - 0.000000000000000009336 88.0
DTH1_k127_6249480_2 Histone deacetylase domain - - - 0.00000000009253 65.0
DTH1_k127_6282235_0 - - - - 0.000000000009551 77.0
DTH1_k127_6282235_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00004621 50.0
DTH1_k127_6284047_0 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 426.0
DTH1_k127_6284047_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 367.0
DTH1_k127_6289799_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 451.0
DTH1_k127_6289799_1 LemA family K03744 - - 0.00000000000000000000000005009 109.0
DTH1_k127_6313494_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 372.0
DTH1_k127_6313494_1 YEATS family - - - 0.0000000000009003 78.0
DTH1_k127_6313494_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000002195 65.0
DTH1_k127_6314255_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 467.0
DTH1_k127_6314255_1 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 341.0
DTH1_k127_6314255_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.000000000000000000000000000000000000000000000000000000000001875 209.0
DTH1_k127_6314255_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000002583 67.0
DTH1_k127_6326105_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 492.0
DTH1_k127_6326105_1 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 324.0
DTH1_k127_6326105_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00003186 46.0
DTH1_k127_6344320_0 PFAM transposase IS66 K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002217 285.0
DTH1_k127_6344320_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002344 263.0
DTH1_k127_6344320_2 alpha beta K06889 - - 0.000000000000000000000000000000000000000000000003258 185.0
DTH1_k127_6344320_3 - - - - 0.0000000000000000000000000000000000003964 147.0
DTH1_k127_6344320_4 PFAM IS66 Orf2 family protein K07484 - - 0.0000000000000000000000000002229 122.0
DTH1_k127_6350799_0 Belongs to the glycosyl hydrolase 57 family - - - 7.989e-241 755.0
DTH1_k127_6350799_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000005474 227.0
DTH1_k127_6350799_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000009066 186.0
DTH1_k127_6355515_0 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 472.0
DTH1_k127_6355515_1 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 363.0
DTH1_k127_6355515_2 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 231.0
DTH1_k127_6355515_3 FecR protein - - - 0.000000000000000000000000000001786 133.0
DTH1_k127_6355515_4 Protein of unknown function (DUF560) - - - 0.000000000000004795 88.0
DTH1_k127_6374758_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.121e-266 834.0
DTH1_k127_6383673_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.057e-259 811.0
DTH1_k127_6383673_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000006179 111.0
DTH1_k127_6383673_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000002029 92.0
DTH1_k127_6407962_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.401e-272 852.0
DTH1_k127_6407962_1 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 464.0
DTH1_k127_6407962_10 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 0.0000000003672 62.0
DTH1_k127_6407962_11 - - - - 0.0002172 51.0
DTH1_k127_6407962_2 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
DTH1_k127_6407962_3 addiction module antidote protein - - - 0.00000000000000000000000000000000000000000005593 162.0
DTH1_k127_6407962_4 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000003788 149.0
DTH1_k127_6407962_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000009457 127.0
DTH1_k127_6407962_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000001765 116.0
DTH1_k127_6407962_7 PFAM Phage Tail Collar Domain - - - 0.00000000000000001024 83.0
DTH1_k127_6407962_8 toxin-antitoxin pair type II binding - - - 0.0000000000000008445 79.0
DTH1_k127_6415742_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 609.0
DTH1_k127_6415742_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 466.0
DTH1_k127_6415742_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000003442 134.0
DTH1_k127_6415742_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000004655 141.0
DTH1_k127_6415742_12 similarity to GP 17427840 K07497 - - 0.00000000000000000000447 97.0
DTH1_k127_6415742_13 integral membrane protein - - - 0.0000007937 54.0
DTH1_k127_6415742_14 integral membrane protein - - - 0.00002196 47.0
DTH1_k127_6415742_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 462.0
DTH1_k127_6415742_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 477.0
DTH1_k127_6415742_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 356.0
DTH1_k127_6415742_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000001608 238.0
DTH1_k127_6415742_6 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
DTH1_k127_6415742_7 PFAM ATP-binding region - - - 0.0000000000000000000000000000000000000000000000000004287 197.0
DTH1_k127_6415742_8 Transposase K07497 - - 0.000000000000000000000000000000000000001796 148.0
DTH1_k127_6415742_9 Alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000002881 154.0
DTH1_k127_6449093_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1089.0
DTH1_k127_6449093_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
DTH1_k127_6449093_2 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000001233 199.0
DTH1_k127_6449093_3 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000001927 163.0
DTH1_k127_6482158_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001009 259.0
DTH1_k127_6482158_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000001106 201.0
DTH1_k127_6487897_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 581.0
DTH1_k127_6487897_1 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000000104 205.0
DTH1_k127_6487897_2 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000115 151.0
DTH1_k127_6487897_3 - - - - 0.000000000000000004077 89.0
DTH1_k127_6487897_4 DNA-binding transcription factor activity K01420 - - 0.00000000000000005466 91.0
DTH1_k127_6522694_0 FAD binding domain K00394 - 1.8.99.2 0.0 1257.0
DTH1_k127_6522694_1 PFAM AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
DTH1_k127_6522694_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
DTH1_k127_6522694_3 PFAM von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000004138 166.0
DTH1_k127_6523033_0 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000005099 239.0
DTH1_k127_6523033_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000003249 206.0
DTH1_k127_6523033_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000001686 210.0
DTH1_k127_6523224_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.887e-202 640.0
DTH1_k127_6523224_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000006598 106.0
DTH1_k127_6523224_2 peptidase - - - 0.000000000000000000007743 94.0
DTH1_k127_656941_0 von Willebrand factor, type A - - - 0.0 1188.0
DTH1_k127_656941_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 567.0
DTH1_k127_656941_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001006 228.0
DTH1_k127_656941_11 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000006292 217.0
DTH1_k127_656941_12 - - - - 0.000000000000000000000000000000000000000000000003008 182.0
DTH1_k127_656941_13 regulation of methylation-dependent chromatin silencing K03684,K09968 - 3.1.13.5 0.0000000000000000000000000000000000000001795 154.0
DTH1_k127_656941_14 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000305 138.0
DTH1_k127_656941_16 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000008739 86.0
DTH1_k127_656941_17 - - - - 0.0000000000000008292 81.0
DTH1_k127_656941_2 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 488.0
DTH1_k127_656941_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 472.0
DTH1_k127_656941_4 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 448.0
DTH1_k127_656941_5 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 346.0
DTH1_k127_656941_6 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 342.0
DTH1_k127_656941_7 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
DTH1_k127_656941_8 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001751 267.0
DTH1_k127_656941_9 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000007148 243.0
DTH1_k127_6600600_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 533.0
DTH1_k127_6600600_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000003508 268.0
DTH1_k127_6600600_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000003172 195.0
DTH1_k127_6659066_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001244 267.0
DTH1_k127_6659066_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000003659 254.0
DTH1_k127_6659066_2 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000001836 135.0
DTH1_k127_6659066_3 Heavy metal-associated domain protein K07213 - - 0.00000000000000000001244 93.0
DTH1_k127_6665160_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 336.0
DTH1_k127_6665160_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000001293 111.0
DTH1_k127_6689761_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.417e-225 703.0
DTH1_k127_6689761_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 392.0
DTH1_k127_6689761_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000002057 169.0
DTH1_k127_6689761_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000121 171.0
DTH1_k127_6689761_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000003395 160.0
DTH1_k127_6689761_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000005873 145.0
DTH1_k127_6689761_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000001728 147.0
DTH1_k127_6689761_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000006659 139.0
DTH1_k127_6689761_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000008698 141.0
DTH1_k127_6689761_17 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000002795 94.0
DTH1_k127_6689761_18 Ribosomal protein L30 K02907 - - 0.00000000000000004486 90.0
DTH1_k127_6689761_19 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000004978 69.0
DTH1_k127_6689761_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 306.0
DTH1_k127_6689761_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000155 271.0
DTH1_k127_6689761_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000362 262.0
DTH1_k127_6689761_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006269 255.0
DTH1_k127_6689761_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000007658 226.0
DTH1_k127_6689761_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000004704 224.0
DTH1_k127_6689761_8 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000000000297 205.0
DTH1_k127_6689761_9 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000288 198.0
DTH1_k127_6690205_0 UvrD REP K03657 - 3.6.4.12 0.0 1011.0
DTH1_k127_6690205_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.313e-194 610.0
DTH1_k127_6690205_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 480.0
DTH1_k127_6690205_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000004638 250.0
DTH1_k127_6690205_4 - - - - 0.0000000000000000000000000000000000000000004858 167.0
DTH1_k127_6710298_0 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000000000000000007514 235.0
DTH1_k127_6710298_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000001401 149.0
DTH1_k127_6730323_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 532.0
DTH1_k127_6730323_1 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 477.0
DTH1_k127_6730323_2 Zinc-finger domain - - - 0.0000000000000000000000000002722 114.0
DTH1_k127_6730323_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000003632 94.0
DTH1_k127_6731603_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1258.0
DTH1_k127_6731603_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 5.923e-269 848.0
DTH1_k127_6731603_2 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 418.0
DTH1_k127_6731603_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 396.0
DTH1_k127_6731603_4 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 318.0
DTH1_k127_6731603_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 292.0
DTH1_k127_6731603_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
DTH1_k127_6731603_7 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000005675 144.0
DTH1_k127_674523_0 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 497.0
DTH1_k127_674523_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 336.0
DTH1_k127_674523_2 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002537 241.0
DTH1_k127_674523_3 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000001079 138.0
DTH1_k127_674523_4 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000235 137.0
DTH1_k127_6756454_0 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 610.0
DTH1_k127_6756454_1 PFAM multicopper oxidase type 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 575.0
DTH1_k127_6756454_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000003817 259.0
DTH1_k127_6756454_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000008286 176.0
DTH1_k127_6760854_0 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001125 254.0
DTH1_k127_6760854_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000001034 164.0
DTH1_k127_6773477_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1641.0
DTH1_k127_6773477_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 543.0
DTH1_k127_6773477_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000002059 171.0
DTH1_k127_6775016_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 517.0
DTH1_k127_6775016_1 Belongs to the DnaA family K10763 - - 0.00000000000000000000000001207 112.0
DTH1_k127_6776396_0 ABC transporter - - - 8.581e-198 622.0
DTH1_k127_6776396_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000001815 205.0
DTH1_k127_6776396_2 protein conserved in bacteria - - - 0.0000000000000000000000000002291 121.0
DTH1_k127_6778932_0 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 305.0
DTH1_k127_6778932_1 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000007616 175.0
DTH1_k127_6785269_0 HELICc2 K03722 - 3.6.4.12 2.226e-274 858.0
DTH1_k127_6785269_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.352e-228 716.0
DTH1_k127_6785269_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 255.0
DTH1_k127_6785269_11 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003135 252.0
DTH1_k127_6785269_12 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000011 179.0
DTH1_k127_6785269_13 Phasin protein - - - 0.00000000000000000000000000000000000000003474 159.0
DTH1_k127_6785269_14 Universal stress protein family - - - 0.00000000000000000000000000000002717 131.0
DTH1_k127_6785269_15 - - - - 0.00000000000000000000000000000217 136.0
DTH1_k127_6785269_16 - - - - 0.0000000001057 66.0
DTH1_k127_6785269_2 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 3.401e-201 646.0
DTH1_k127_6785269_3 Cytochrome c bacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 608.0
DTH1_k127_6785269_4 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 540.0
DTH1_k127_6785269_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 426.0
DTH1_k127_6785269_6 PFAM Zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 361.0
DTH1_k127_6785269_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 324.0
DTH1_k127_6785269_8 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 328.0
DTH1_k127_6785269_9 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
DTH1_k127_6792365_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1905.0
DTH1_k127_6792365_1 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001525 258.0
DTH1_k127_6792365_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
DTH1_k127_6792365_3 photosynthesis - - - 0.00000000000000000000000000000000000000000000000001162 184.0
DTH1_k127_6792422_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.937e-265 822.0
DTH1_k127_6792422_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 1.327e-194 622.0
DTH1_k127_6792422_2 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 427.0
DTH1_k127_6792422_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 409.0
DTH1_k127_6792422_4 - - - - 0.0000000000001209 78.0
DTH1_k127_6792422_5 - - - - 0.000000000000278 81.0
DTH1_k127_6792422_6 Major facilitator Superfamily - - - 0.0000000004744 66.0
DTH1_k127_6802368_0 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 516.0
DTH1_k127_6802368_1 chorismate binding enzyme - - - 0.00002609 49.0
DTH1_k127_6811004_0 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 455.0
DTH1_k127_6811004_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 416.0
DTH1_k127_6811004_2 Short-chain dehydrogenase reductase SDR - - - 0.000007581 49.0
DTH1_k127_6815701_0 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 297.0
DTH1_k127_6815701_1 Phospholipid methyltransferase - - - 0.000000000000000001461 94.0
DTH1_k127_6815701_2 Phospholipid methyltransferase - - - 0.000000000001478 69.0
DTH1_k127_6822362_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 294.0
DTH1_k127_6822362_1 PFAM transport-associated - - - 0.00000000000000000000000000000000000000000000000000006091 193.0
DTH1_k127_6822362_2 Cytidylyltransferase-like K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000003612 170.0
DTH1_k127_6827023_0 aminopeptidase N K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008232 267.0
DTH1_k127_6827023_1 Peptidase M15 K03791 - - 0.000000000000000000000000000000000000000000000000000000000000001398 224.0
DTH1_k127_6832553_0 Protein of unknown function, DUF255 K06888 - - 1.262e-279 883.0
DTH1_k127_6832553_1 amino acid ABC transporter K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 476.0
DTH1_k127_6832553_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 392.0
DTH1_k127_6832553_3 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000001732 203.0
DTH1_k127_6832553_4 - - - - 0.00000000000000000000000000000000000000000000000000004623 190.0
DTH1_k127_6832553_5 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000003237 134.0
DTH1_k127_6845834_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 597.0
DTH1_k127_6845834_1 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 368.0
DTH1_k127_6873455_0 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 602.0
DTH1_k127_6873455_1 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000005046 128.0
DTH1_k127_6903582_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 445.0
DTH1_k127_6903582_1 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 424.0
DTH1_k127_6903582_2 Putative methyltransferase K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 336.0
DTH1_k127_6903582_3 Formaldehyde-activating enzyme (Fae) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
DTH1_k127_6903582_4 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001969 270.0
DTH1_k127_6903582_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000007515 247.0
DTH1_k127_6903582_6 diguanylate cyclase - - - 0.0000000000000000000003775 98.0
DTH1_k127_6903582_7 ThiS family K03154 - - 0.000000000000000000002249 95.0
DTH1_k127_6903582_8 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000008409 48.0
DTH1_k127_69116_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 602.0
DTH1_k127_69116_1 Soluble lytic murein transglycosylase L domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 567.0
DTH1_k127_69116_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 362.0
DTH1_k127_6915351_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 611.0
DTH1_k127_6915351_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000009311 169.0
DTH1_k127_6921086_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1363.0
DTH1_k127_6921086_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 7.65e-220 689.0
DTH1_k127_6921086_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 572.0
DTH1_k127_6921086_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 556.0
DTH1_k127_6921086_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 463.0
DTH1_k127_6921086_5 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 372.0
DTH1_k127_6921086_6 Protein conserved in bacteria - - - 0.0000000000000912 84.0
DTH1_k127_6921086_7 ATPase (AAA K06923 - - 0.0006968 44.0
DTH1_k127_693387_0 glutaminyl-tRNA K01886 - 6.1.1.18 1.846e-280 871.0
DTH1_k127_693387_1 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
DTH1_k127_693387_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
DTH1_k127_693387_3 LysR substrate binding domain - - - 0.000000000000008676 75.0
DTH1_k127_69599_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 344.0
DTH1_k127_69599_1 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000000002196 236.0
DTH1_k127_69599_2 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000619 183.0
DTH1_k127_69599_3 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000524 174.0
DTH1_k127_7004177_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 2.681e-300 933.0
DTH1_k127_7004177_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 5.632e-293 903.0
DTH1_k127_7004177_2 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 461.0
DTH1_k127_7004177_3 Two-component sensor kinase N-terminal K07645 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000003457 121.0
DTH1_k127_7005868_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2343.0
DTH1_k127_7005868_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2050.0
DTH1_k127_7005868_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1196.0
DTH1_k127_7005868_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009877 261.0
DTH1_k127_7005868_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001377 227.0
DTH1_k127_7005868_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000007233 119.0
DTH1_k127_7009327_0 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000003604 219.0
DTH1_k127_7009327_1 - - - - 0.00000001061 64.0
DTH1_k127_7010782_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1086.0
DTH1_k127_7010782_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000003035 148.0
DTH1_k127_7010782_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00002278 48.0
DTH1_k127_7034071_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 2.595e-201 634.0
DTH1_k127_7034071_1 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 378.0
DTH1_k127_7034071_2 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000009585 195.0
DTH1_k127_7034071_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000008563 189.0
DTH1_k127_7044207_0 Histidine kinase - - - 1.149e-234 745.0
DTH1_k127_7044207_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
DTH1_k127_7044207_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000705 196.0
DTH1_k127_7044207_3 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000003854 180.0
DTH1_k127_7044207_4 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000001468 158.0
DTH1_k127_7044207_5 Putative zinc-finger - - - 0.000000000001084 72.0
DTH1_k127_7044207_6 - - - - 0.00000001124 63.0
DTH1_k127_7045702_0 type II secretion system protein K02454 - - 1.947e-243 763.0
DTH1_k127_7056310_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 5.165e-199 649.0
DTH1_k127_7056310_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 314.0
DTH1_k127_7056310_2 Glycine-zipper domain - - - 0.00000000000000000000008092 101.0
DTH1_k127_7056310_3 - - - - 0.0000000000000000000001172 104.0
DTH1_k127_7059785_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 421.0
DTH1_k127_7059785_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 389.0
DTH1_k127_7059785_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000006525 218.0
DTH1_k127_7059785_3 NusG domain II - - - 0.000000382 52.0
DTH1_k127_7073850_0 nitrous oxide reductase K00376 - 1.7.2.4 0.0 1044.0
DTH1_k127_7073850_1 FMN_bind - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 485.0
DTH1_k127_7077653_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1114.0
DTH1_k127_7078241_0 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 388.0
DTH1_k127_7078241_1 Phospholipase D Active site motif K06131 - - 0.00000000000000000000000000000000000000000000000000000002436 203.0
DTH1_k127_7078241_2 IMP dehydrogenase activity - - - 0.000000000000000000000000000000000002016 148.0
DTH1_k127_7078241_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.00000000000005183 83.0
DTH1_k127_7078241_4 mttA/Hcf106 family K03116 - - 0.000000000003529 68.0
DTH1_k127_7078241_5 antisigma factor binding K02066,K02660,K04749,K04757,K05946,K06378 - 2.4.1.187,2.7.11.1 0.000000002358 65.0
DTH1_k127_7085372_0 Tetratricopeptide repeat - - - 1.848e-203 644.0
DTH1_k127_7085372_1 Ammonium Transporter Family K03320,K06580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 588.0
DTH1_k127_7085372_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001376 224.0
DTH1_k127_7085372_3 - - - - 0.000000000000000000000000001036 125.0
DTH1_k127_7085372_4 transcriptional regulator, SARP family - - - 0.000002324 59.0
DTH1_k127_7085372_5 TIR domain - - - 0.00009022 54.0
DTH1_k127_7107530_0 von Willebrand factor (vWF) type A domain K16259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000246 254.0
DTH1_k127_7107530_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009231 231.0
DTH1_k127_7107530_2 dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000002103 222.0
DTH1_k127_7107530_3 - - - - 0.000000000000000000005414 96.0
DTH1_k127_7132442_0 Multi-copper K06324,K22350 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 465.0
DTH1_k127_7132442_1 Cytochrome c - - - 0.00000000000000000000002722 104.0
DTH1_k127_7133368_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.728e-220 688.0
DTH1_k127_7133368_1 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 308.0
DTH1_k127_7133368_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000001351 86.0
DTH1_k127_7141480_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 580.0
DTH1_k127_7141480_1 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000002378 193.0
DTH1_k127_7141480_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000001068 171.0
DTH1_k127_7143865_0 Esterase of the alpha-beta hydrolase superfamily - - - 2.745e-232 747.0
DTH1_k127_7149429_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 479.0
DTH1_k127_7149429_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000001393 190.0
DTH1_k127_7149429_2 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000001157 168.0
DTH1_k127_7149429_3 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000008235 150.0
DTH1_k127_7149429_4 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000001391 143.0
DTH1_k127_7149429_5 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000009583 112.0
DTH1_k127_7153082_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.437e-208 653.0
DTH1_k127_7153082_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 497.0
DTH1_k127_7153082_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 387.0
DTH1_k127_7153082_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000001086 57.0
DTH1_k127_7179840_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.9e-221 690.0
DTH1_k127_7179840_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 552.0
DTH1_k127_7179840_2 TIGRFAM squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 365.0
DTH1_k127_7179840_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 353.0
DTH1_k127_7179840_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 297.0
DTH1_k127_7179840_5 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000001877 91.0
DTH1_k127_7179840_6 - - - - 0.0005122 52.0
DTH1_k127_7181277_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.107e-301 928.0
DTH1_k127_7181277_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 576.0
DTH1_k127_7181277_2 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 502.0
DTH1_k127_7181277_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 360.0
DTH1_k127_7181277_4 4Fe-4S dicluster domain K18930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001252 277.0
DTH1_k127_7296056_0 Large family of predicted nucleotide-binding domains K07175 - - 6.661e-253 785.0
DTH1_k127_7296056_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 9.542e-225 704.0
DTH1_k127_7296056_2 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 333.0
DTH1_k127_7296056_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 302.0
DTH1_k127_7296056_4 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007663 256.0
DTH1_k127_7296056_5 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000001754 227.0
DTH1_k127_7296056_6 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000004596 211.0
DTH1_k127_7296056_7 Ribosomal protein S18 K02963 - - 0.0000000000000000000000000000000004175 133.0
DTH1_k127_7323854_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 486.0
DTH1_k127_7323854_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 308.0
DTH1_k127_7323854_2 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000001685 228.0
DTH1_k127_7325456_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 573.0
DTH1_k127_7325456_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
DTH1_k127_7325456_2 Trypsin - - - 0.0000000000000000000000000000000000000000000000004805 193.0
DTH1_k127_7325456_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000001282 186.0
DTH1_k127_7325456_4 - - - - 0.00000000000000000000000000000000000000001651 160.0
DTH1_k127_7325456_5 DsrC like protein - - - 0.00000000000000000000000000000000000000002531 157.0
DTH1_k127_7325456_6 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000904 145.0
DTH1_k127_7325456_7 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000003768 109.0
DTH1_k127_7325456_8 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000361 93.0
DTH1_k127_7325456_9 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000007449 86.0
DTH1_k127_7326265_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1515.0
DTH1_k127_7326265_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1513.0
DTH1_k127_7326265_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
DTH1_k127_7326265_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 374.0
DTH1_k127_7326265_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000004791 139.0
DTH1_k127_7326265_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000002383 138.0
DTH1_k127_7326265_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000292 117.0
DTH1_k127_7326265_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000176 69.0
DTH1_k127_7337501_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 448.0
DTH1_k127_7337501_1 Protein of unknown function - - - 0.000000000000000000000000000000000000000002607 162.0
DTH1_k127_7360527_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.461e-301 936.0
DTH1_k127_7360527_1 His Kinase A (phospho-acceptor) domain - - - 8.024e-240 752.0
DTH1_k127_7360527_10 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000002298 175.0
DTH1_k127_7360527_11 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000007192 150.0
DTH1_k127_7360527_12 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000001848 131.0
DTH1_k127_7360527_13 - - - - 0.00000000000000002335 88.0
DTH1_k127_7360527_14 Recombinase zinc beta ribbon domain K06400 - - 0.000000002296 62.0
DTH1_k127_7360527_2 DNA polymerase III K02342 - 2.7.7.7 1.222e-238 757.0
DTH1_k127_7360527_3 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.003e-214 672.0
DTH1_k127_7360527_4 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 5.21e-205 686.0
DTH1_k127_7360527_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 475.0
DTH1_k127_7360527_6 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 367.0
DTH1_k127_7360527_7 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 315.0
DTH1_k127_7360527_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000009685 244.0
DTH1_k127_7360527_9 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000008179 175.0
DTH1_k127_7361482_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.554e-265 835.0
DTH1_k127_7374391_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
DTH1_k127_7374391_1 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.00000000000000000000000009225 109.0
DTH1_k127_7374391_2 PFAM TOBE domain protein - - - 0.000000000000000001779 87.0
DTH1_k127_7440956_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.049e-251 781.0
DTH1_k127_7440956_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 4.094e-218 685.0
DTH1_k127_7440956_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 309.0
DTH1_k127_7440956_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
DTH1_k127_7440956_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000005051 192.0
DTH1_k127_7440956_5 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000002016 177.0
DTH1_k127_7440956_6 HNH nucleases - - - 0.00000000000000000000000000000000000000000000001097 177.0
DTH1_k127_7440956_7 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.000000000000000000000000000008855 124.0
DTH1_k127_7440956_8 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000006706 66.0
DTH1_k127_7441666_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 563.0
DTH1_k127_7441666_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 361.0
DTH1_k127_7441666_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000004621 128.0
DTH1_k127_7441666_3 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000001875 118.0
DTH1_k127_7443553_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 541.0
DTH1_k127_7443553_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 494.0
DTH1_k127_7443553_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
DTH1_k127_7443553_3 PFAM membrane protein of K08972 - - 0.0000000000000000000000000000000000000253 148.0
DTH1_k127_7443553_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000001022 110.0
DTH1_k127_7491397_0 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 413.0
DTH1_k127_7491397_1 Amidohydrolase family K00200 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 391.0
DTH1_k127_7504920_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 545.0
DTH1_k127_7504920_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 336.0
DTH1_k127_7520850_0 Amino acid kinase family - - - 0.0000000000000000000000000000000000000000000004973 173.0
DTH1_k127_7520850_1 4-HFC-P synthase - - - 0.000000000000000000000000000000000000000000003464 169.0
DTH1_k127_7520850_2 H4MPT-linked C1 transfer pathway protein - - - 0.0000000003247 64.0
DTH1_k127_7541373_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 3.503e-204 642.0
DTH1_k127_7541373_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000002344 160.0
DTH1_k127_7543099_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 477.0
DTH1_k127_7543099_1 serine threonine protein kinase - - - 0.0000000000000000000000000006275 117.0
DTH1_k127_7608303_0 Cytochrome b(N-terminal)/b6/petB - - - 1.046e-253 798.0
DTH1_k127_7608303_1 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000164 262.0
DTH1_k127_7608303_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000002274 156.0
DTH1_k127_7608303_3 - - - - 0.000000000000000000000000000000000000000632 154.0
DTH1_k127_7608303_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0005623 44.0
DTH1_k127_7611506_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 326.0
DTH1_k127_7611506_1 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000009448 201.0
DTH1_k127_7611506_2 - - - - 0.0000000000000000000000000000000000000000000000000001242 194.0
DTH1_k127_7611506_3 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000001183 182.0
DTH1_k127_7654873_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
DTH1_k127_7654873_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 395.0
DTH1_k127_7654873_2 - - - - 0.00000000000000000001044 98.0
DTH1_k127_7655813_0 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000007778 164.0
DTH1_k127_7655813_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000006464 51.0
DTH1_k127_7678586_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 7.355e-211 665.0
DTH1_k127_7678586_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00003723 46.0
DTH1_k127_7690887_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1035.0
DTH1_k127_7690887_1 TonB-dependent Receptor Plug K02014 - - 3.011e-251 798.0
DTH1_k127_7690887_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 534.0
DTH1_k127_7690887_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 302.0
DTH1_k127_7690887_4 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
DTH1_k127_7690887_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
DTH1_k127_7690887_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000002981 108.0
DTH1_k127_7690887_7 Mut7-C ubiquitin - - - 0.00000000000000000000001721 113.0
DTH1_k127_7690887_8 - - - - 0.0000000000000002644 89.0
DTH1_k127_7707720_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 522.0
DTH1_k127_7707720_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000004212 242.0
DTH1_k127_7717212_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 526.0
DTH1_k127_7717212_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
DTH1_k127_7717212_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 396.0
DTH1_k127_7717212_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000002033 160.0
DTH1_k127_7717212_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000002024 141.0
DTH1_k127_7717212_5 - - - - 0.000002501 53.0
DTH1_k127_7723236_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
DTH1_k127_7723236_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 356.0
DTH1_k127_7723236_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 340.0
DTH1_k127_7723236_3 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 320.0
DTH1_k127_7723236_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000002768 114.0
DTH1_k127_7723236_5 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000000002484 111.0
DTH1_k127_7779013_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 461.0
DTH1_k127_7779013_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 349.0
DTH1_k127_7779013_2 ATP-grasp domain - - - 0.00000001028 58.0
DTH1_k127_7786963_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.357e-251 783.0
DTH1_k127_7786963_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 2.244e-233 727.0
DTH1_k127_7786963_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 548.0
DTH1_k127_7786963_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 498.0
DTH1_k127_7786963_4 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
DTH1_k127_7786963_5 membrane protein, terc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 305.0
DTH1_k127_7786963_6 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000008138 171.0
DTH1_k127_7786963_7 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000001024 162.0
DTH1_k127_7787186_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1396.0
DTH1_k127_7787186_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 602.0
DTH1_k127_7787186_2 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 477.0
DTH1_k127_7787186_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 443.0
DTH1_k127_7787186_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 404.0
DTH1_k127_7787186_5 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000113 226.0
DTH1_k127_7787186_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000041 194.0
DTH1_k127_7787186_7 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.000000000000000000000000000001644 125.0
DTH1_k127_7793630_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
DTH1_k127_7793630_1 Alpha beta hydrolase - - - 0.0000000000000000000000173 102.0
DTH1_k127_7794342_0 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 321.0
DTH1_k127_7794342_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 288.0
DTH1_k127_7794342_2 - - - - 0.0000000000000000000000000000000000000003371 155.0
DTH1_k127_7837296_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 538.0
DTH1_k127_7837296_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000275 209.0
DTH1_k127_7837296_2 TRANSCRIPTIONal - - - 0.000000000000000000000003274 105.0
DTH1_k127_7839475_0 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000003125 205.0
DTH1_k127_7839475_1 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000000000000009271 192.0
DTH1_k127_7842020_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1094.0
DTH1_k127_7853_0 TonB-dependent receptor K02014 - - 1.041e-216 702.0
DTH1_k127_7853_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 385.0
DTH1_k127_7853_2 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 274.0
DTH1_k127_7853_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003938 261.0
DTH1_k127_7853_4 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 262.0
DTH1_k127_7853_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000006677 199.0
DTH1_k127_7853_6 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000001168 192.0
DTH1_k127_7853_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000001912 53.0
DTH1_k127_786603_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.485e-297 927.0
DTH1_k127_786603_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.115e-232 728.0
DTH1_k127_786603_2 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 442.0
DTH1_k127_786603_3 GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003427 267.0
DTH1_k127_786603_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000001948 183.0
DTH1_k127_786603_5 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000004513 166.0
DTH1_k127_786603_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000009741 128.0
DTH1_k127_786603_7 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0000000000000000000208 94.0
DTH1_k127_786603_8 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000005172 77.0
DTH1_k127_787342_0 PFAM MgtC SapB transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 482.0
DTH1_k127_787342_1 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 389.0
DTH1_k127_7920847_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 583.0
DTH1_k127_7920847_1 ABC transporter K02013 - 3.6.3.34 0.00000000000000003866 83.0
DTH1_k127_7921832_0 PFAM ROK family protein K00845,K00847 - 2.7.1.2,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 398.0
DTH1_k127_7921832_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003009 295.0
DTH1_k127_7921832_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000001483 63.0
DTH1_k127_7933993_0 PFAM multicopper oxidase type 2 K22350 - 1.16.3.3 4.503e-310 987.0
DTH1_k127_7933993_1 Protein conserved in bacteria - - - 0.000000000000000005633 100.0
DTH1_k127_7934761_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 395.0
DTH1_k127_7934761_1 - - - - 0.0000000000000000000000000000000000000000000000000000001413 206.0
DTH1_k127_7934761_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000003245 180.0
DTH1_k127_7940541_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 361.0
DTH1_k127_7940541_1 - - - - 0.00000000000000000000000000000000000000000000000007419 202.0
DTH1_k127_7940541_2 Chaperone - - - 0.0000000000000000000000000000000000000000000000001227 188.0
DTH1_k127_7940541_3 Phosphoribosyl transferase domain - - - 0.00000000000000000000005511 99.0
DTH1_k127_7940541_4 - - - - 0.0000000001878 71.0
DTH1_k127_7940541_5 - - - - 0.000000007655 64.0
DTH1_k127_7959280_0 B12 binding domain K00548 - 2.1.1.13 0.0 1717.0
DTH1_k127_7959280_1 (GGDEF) domain K21024 - 3.1.4.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 507.0
DTH1_k127_7959280_2 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000006289 222.0
DTH1_k127_7959280_4 NYN domain - - - 0.000000000000004894 75.0
DTH1_k127_7959589_0 Belongs to the peptidase S8 family - - - 7.676e-208 655.0
DTH1_k127_7959589_1 Flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004378 244.0
DTH1_k127_7959589_2 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000000000000000000000000000000000000001677 242.0
DTH1_k127_7959589_3 GAF domain K21405 - - 0.000000000001138 70.0
DTH1_k127_7966544_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1370.0
DTH1_k127_7966544_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 1.032e-222 696.0
DTH1_k127_7966544_2 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000001099 211.0
DTH1_k127_7970849_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 434.0
DTH1_k127_7970849_1 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 352.0
DTH1_k127_7970849_2 - - - - 0.0000000000000000000003301 98.0
DTH1_k127_7970849_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000001108 86.0
DTH1_k127_7972800_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 6.614e-250 784.0
DTH1_k127_7972800_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.21e-233 728.0
DTH1_k127_7972800_10 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000001033 183.0
DTH1_k127_7972800_11 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000131 175.0
DTH1_k127_7972800_12 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000003956 136.0
DTH1_k127_7972800_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000005207 140.0
DTH1_k127_7972800_14 - - - - 0.000000000000000000000000000000008954 132.0
DTH1_k127_7972800_15 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000002042 119.0
DTH1_k127_7972800_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.062e-196 617.0
DTH1_k127_7972800_3 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 544.0
DTH1_k127_7972800_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 544.0
DTH1_k127_7972800_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 502.0
DTH1_k127_7972800_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 338.0
DTH1_k127_7972800_7 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 303.0
DTH1_k127_7972800_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 303.0
DTH1_k127_7972800_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003849 273.0
DTH1_k127_8003214_0 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 352.0
DTH1_k127_8003214_1 diguanylate cyclase - - - 0.00000000000000000000000000000000003211 141.0
DTH1_k127_8006438_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 397.0
DTH1_k127_8006438_1 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.000000000001438 68.0
DTH1_k127_8006438_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000006245 49.0
DTH1_k127_8016577_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 3.997e-224 715.0
DTH1_k127_8016577_1 Pfam Sulfatase K01130 - 3.1.6.1 1.2e-220 694.0
DTH1_k127_8016577_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 463.0
DTH1_k127_8016577_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 331.0
DTH1_k127_8016577_4 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 304.0
DTH1_k127_8016577_5 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K02805,K18653 - 2.6.1.104,2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
DTH1_k127_8016577_6 dTDP-6-deoxy-3,4-keto-hexulose isomerase - - - 0.000000000000000000000000000000000000000404 161.0
DTH1_k127_8016577_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000002367 143.0
DTH1_k127_8016577_8 - - - - 0.000000000001425 70.0
DTH1_k127_8016577_9 membrane - - - 0.00006316 54.0
DTH1_k127_8018534_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 315.0
DTH1_k127_8018534_1 Molybdenum ABC transporter K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 292.0
DTH1_k127_8018534_2 ATPases associated with a variety of cellular activities K02010,K02017,K11072 - 3.6.3.29,3.6.3.30,3.6.3.31 0.0000000000000000000000000000000000000003581 154.0
DTH1_k127_8030719_0 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 295.0
DTH1_k127_8030719_1 - - - - 0.00000000000000000000000000000000000000000000009114 191.0
DTH1_k127_8030719_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000002699 181.0
DTH1_k127_8062730_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.816e-212 668.0
DTH1_k127_8062730_1 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009989 302.0
DTH1_k127_8062730_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000491 158.0
DTH1_k127_8077567_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.222e-320 986.0
DTH1_k127_8077567_1 PFAM Cysteine-rich - - - 1.763e-226 713.0
DTH1_k127_8077567_2 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 521.0
DTH1_k127_8077567_3 glycolate oxidase subunit GlcD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 344.0
DTH1_k127_8077567_4 ATP synthase (C/AC39) subunit K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 301.0
DTH1_k127_8077567_5 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004178 220.0
DTH1_k127_8077567_6 - - - - 0.0000000000000000003272 91.0
DTH1_k127_809318_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
DTH1_k127_809318_1 - - - - 0.000000000000000000000000000002401 134.0
DTH1_k127_8099651_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
DTH1_k127_8099651_1 LemA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006436 280.0
DTH1_k127_8099651_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005616 256.0
DTH1_k127_8099651_3 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
DTH1_k127_8099651_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002331 218.0
DTH1_k127_8099651_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000006896 212.0
DTH1_k127_8099651_6 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003713 199.0
DTH1_k127_8099651_7 Glycine zipper 2TM domain - - - 0.00000009868 60.0
DTH1_k127_8099651_8 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.000158 44.0
DTH1_k127_8115609_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 382.0
DTH1_k127_8115609_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 306.0
DTH1_k127_8115609_2 Major facilitator Superfamily - - - 0.0000000000000711 75.0
DTH1_k127_8133261_0 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 322.0
DTH1_k127_8133261_1 Cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000001139 237.0
DTH1_k127_8133261_2 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000003127 164.0
DTH1_k127_8133261_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0008741 42.0
DTH1_k127_8166666_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000004217 236.0
DTH1_k127_8166666_1 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001733 187.0
DTH1_k127_8166666_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000927 76.0
DTH1_k127_8209096_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 606.0
DTH1_k127_8209096_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 408.0
DTH1_k127_8209096_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000008529 237.0
DTH1_k127_8209096_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000001003 237.0
DTH1_k127_8209096_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000002307 143.0
DTH1_k127_8209096_5 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000007456 91.0
DTH1_k127_8222568_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 1.138e-194 611.0
DTH1_k127_8222568_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 512.0
DTH1_k127_8222568_2 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 377.0
DTH1_k127_8222568_3 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000244 205.0
DTH1_k127_8222568_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000001761 116.0
DTH1_k127_8222568_5 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000003115 64.0
DTH1_k127_8240273_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 387.0
DTH1_k127_8240273_1 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000177 128.0
DTH1_k127_8240273_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000003319 89.0
DTH1_k127_8244354_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 467.0
DTH1_k127_8244354_1 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 386.0
DTH1_k127_8244354_2 Peptidase S24-like - - - 0.00000000000000000000000000000001789 142.0
DTH1_k127_8244354_3 DsrC like protein K11179 - - 0.0000000000000000000000000000006502 126.0
DTH1_k127_8244354_4 - - - - 0.00000000000003287 81.0
DTH1_k127_8244354_5 - - - - 0.000000000005143 71.0
DTH1_k127_8254664_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.728e-222 704.0
DTH1_k127_8254664_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 415.0
DTH1_k127_8254664_2 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000002941 162.0
DTH1_k127_8263997_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 509.0
DTH1_k127_8263997_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 348.0
DTH1_k127_8263997_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000096 288.0
DTH1_k127_8270992_0 PFAM multicopper oxidase type 2 K22350 - 1.16.3.3 3.5e-323 1021.0
DTH1_k127_8270992_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 3.487e-195 620.0
DTH1_k127_8270992_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 407.0
DTH1_k127_8270992_3 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
DTH1_k127_8270992_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 321.0
DTH1_k127_8270992_5 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000008288 136.0
DTH1_k127_8274185_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 386.0
DTH1_k127_8274185_1 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000000004247 154.0
DTH1_k127_8274185_2 Outer membrane efflux protein - - - 0.0000000000000347 75.0
DTH1_k127_8274185_3 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.00002775 53.0
DTH1_k127_8293085_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 467.0
DTH1_k127_8293085_1 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 331.0
DTH1_k127_8293085_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000166 230.0
DTH1_k127_8293085_3 tellurite resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000193 216.0
DTH1_k127_8293085_4 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.0000000000000000000000000000000000000000000001067 177.0
DTH1_k127_8294046_0 Zn-dependent protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 341.0
DTH1_k127_8294046_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000547 138.0
DTH1_k127_8294046_2 PFAM Rhomboid family - - - 0.0000000003126 72.0
DTH1_k127_8300783_0 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 419.0
DTH1_k127_8300783_1 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 317.0
DTH1_k127_8300783_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 285.0
DTH1_k127_8300783_3 - - - - 0.0000000000000000000000000000003831 128.0
DTH1_k127_8318281_0 type I secretion membrane fusion K02022,K12537 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 335.0
DTH1_k127_8318281_1 Peptidase S8 K08651,K14645 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000009954 245.0
DTH1_k127_8318281_2 Protein of unknown function (DUF3467) - - - 0.0002032 50.0
DTH1_k127_8335155_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 550.0
DTH1_k127_8335155_1 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 351.0
DTH1_k127_8335155_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005672 261.0
DTH1_k127_8335155_3 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000001592 182.0
DTH1_k127_8335155_4 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000113 156.0
DTH1_k127_8350098_0 Outer membrane protein beta-barrel family - - - 6.725e-277 873.0
DTH1_k127_8350098_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000001277 140.0
DTH1_k127_8357623_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1073.0
DTH1_k127_8357623_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000009139 226.0
DTH1_k127_8373916_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 293.0
DTH1_k127_8373916_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005068 241.0
DTH1_k127_8373916_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000003119 158.0
DTH1_k127_8384880_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 3.923e-215 688.0
DTH1_k127_8384880_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 385.0
DTH1_k127_8385912_0 4Fe-4S dicluster domain - - - 1.327e-232 745.0
DTH1_k127_8385912_1 Protein of unknown function (DUF3306) - - - 0.00000000000000000000004701 103.0
DTH1_k127_8416639_0 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 490.0
DTH1_k127_8416639_1 SCO1 SenC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
DTH1_k127_8416639_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001519 266.0
DTH1_k127_8416639_3 COG0790 FOG TPR repeat, SEL1 subfamily K07126 GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564 - 0.00000000000000000000000000000000000000000000000000000001552 209.0
DTH1_k127_8431939_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1711.0
DTH1_k127_8431939_1 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 509.0
DTH1_k127_8431939_10 diguanylate cyclase - - - 0.00000008585 54.0
DTH1_k127_8431939_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 371.0
DTH1_k127_8431939_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 348.0
DTH1_k127_8431939_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 322.0
DTH1_k127_8431939_5 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
DTH1_k127_8431939_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000006193 182.0
DTH1_k127_8431939_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000000000000000000000000000000000000006372 173.0
DTH1_k127_8431939_8 - - - - 0.0000000000000000000000000000000000000000002657 178.0
DTH1_k127_8431939_9 diguanylate cyclase - - - 0.0000000000000000000000000002091 128.0
DTH1_k127_8465119_0 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000001642 173.0
DTH1_k127_8465119_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000005048 110.0
DTH1_k127_8465119_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000939 58.0
DTH1_k127_847289_0 PFAM Peptidase M16 K07263 - - 3.674e-210 661.0
DTH1_k127_847289_1 PFAM Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 535.0
DTH1_k127_847289_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000006588 241.0
DTH1_k127_847289_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000002837 207.0
DTH1_k127_8502341_0 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 343.0
DTH1_k127_8502341_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000473 201.0
DTH1_k127_8502341_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000001201 147.0
DTH1_k127_8502341_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000004378 93.0
DTH1_k127_853167_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 462.0
DTH1_k127_853167_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 380.0
DTH1_k127_853167_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004251 254.0
DTH1_k127_8547267_0 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 610.0
DTH1_k127_8547267_1 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000000000001192 189.0
DTH1_k127_85809_0 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 377.0
DTH1_k127_85809_1 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000002862 240.0
DTH1_k127_85809_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000003011 220.0
DTH1_k127_85809_3 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000001575 120.0
DTH1_k127_8611977_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 589.0
DTH1_k127_8611977_1 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 392.0
DTH1_k127_8611977_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000003996 194.0
DTH1_k127_8611977_3 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000004322 149.0
DTH1_k127_8621255_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1069.0
DTH1_k127_8621255_1 Type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 529.0
DTH1_k127_8621255_2 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000006209 207.0
DTH1_k127_8621255_3 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000005429 188.0
DTH1_k127_8622012_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.037e-260 822.0
DTH1_k127_8622012_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 504.0
DTH1_k127_8622012_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000003645 241.0
DTH1_k127_8622012_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
DTH1_k127_8622012_4 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000101 156.0
DTH1_k127_8622012_5 - - - - 0.000000000000001389 79.0
DTH1_k127_8623051_0 Domain of unknown function (DUF3400) - - - 0.0 1958.0
DTH1_k127_8623051_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 414.0
DTH1_k127_8623051_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 389.0
DTH1_k127_8623051_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 338.0
DTH1_k127_8623051_4 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000001152 213.0
DTH1_k127_8623051_5 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000001285 177.0
DTH1_k127_8623051_6 membrane - - - 0.000000000000000000000000000000000000000000000009304 177.0
DTH1_k127_8623051_8 import inner membrane translocase subunit Tim44 - - - 0.00001091 48.0
DTH1_k127_8639191_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 2.654e-230 724.0
DTH1_k127_8665383_0 Glucose / Sorbosone dehydrogenase - - - 2.371e-234 730.0
DTH1_k127_8665383_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.112e-215 684.0
DTH1_k127_8665383_2 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 265.0
DTH1_k127_8665383_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000002284 205.0
DTH1_k127_8665383_4 Cytochrome c - - - 0.00000000000000000000008307 109.0
DTH1_k127_867561_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1433.0
DTH1_k127_867561_1 24 kD subunit K00122 - 1.17.1.9 2.789e-276 859.0
DTH1_k127_867561_2 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 344.0
DTH1_k127_867561_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 291.0
DTH1_k127_867561_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000005722 233.0
DTH1_k127_867561_5 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000009149 131.0
DTH1_k127_867561_6 - - - - 0.0000000000000000000000001637 115.0
DTH1_k127_867561_7 Protein of unknown function (DUF2889) - - - 0.000000004419 62.0
DTH1_k127_8681024_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 4.55e-222 695.0
DTH1_k127_8681024_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
DTH1_k127_8681024_2 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000002314 194.0
DTH1_k127_8681024_3 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000003239 207.0
DTH1_k127_8681024_4 ribonuclease II K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000007447 177.0
DTH1_k127_8681024_5 Protein of unknown function (DUF3568) - - - 0.0000000000000000000000003523 111.0
DTH1_k127_8682056_0 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 307.0
DTH1_k127_8685245_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 494.0
DTH1_k127_8685245_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 412.0
DTH1_k127_8685245_2 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000001636 208.0
DTH1_k127_8685245_3 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000007382 213.0
DTH1_k127_8696836_0 TIGRFAM type I secretion system ATPase K06148,K12536 - - 2.628e-196 628.0
DTH1_k127_8696836_1 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022,K12537 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 507.0
DTH1_k127_8696836_2 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 293.0
DTH1_k127_8704375_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.035e-232 725.0
DTH1_k127_8704375_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.342e-202 637.0
DTH1_k127_8704375_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 356.0
DTH1_k127_8704375_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 328.0
DTH1_k127_8704375_4 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000007537 209.0
DTH1_k127_8704375_5 - - - - 0.0000000000000000000000044 106.0
DTH1_k127_8704375_6 - - - - 0.000000000000000000001682 96.0
DTH1_k127_8709739_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 8.338e-268 833.0
DTH1_k127_8724245_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 1.868e-250 782.0
DTH1_k127_8735473_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1065.0
DTH1_k127_8735473_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.449e-235 733.0
DTH1_k127_8735473_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000001497 80.0
DTH1_k127_8735473_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000001838 64.0
DTH1_k127_8737026_0 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 448.0
DTH1_k127_8739395_0 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000001785 125.0
DTH1_k127_8739395_1 - - - - 0.000000000000000000002325 100.0
DTH1_k127_8739395_2 Site-specific recombinase - - - 0.0000000000000000001126 102.0
DTH1_k127_8739395_3 - - - - 0.00006775 53.0
DTH1_k127_8751070_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1114.0
DTH1_k127_8751070_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 554.0
DTH1_k127_8751070_2 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 287.0
DTH1_k127_8809466_0 Transposase DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004982 291.0
DTH1_k127_8845584_0 Two component regulator three Y domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000562 260.0
DTH1_k127_8845584_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000002873 60.0
DTH1_k127_8860677_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.407e-265 832.0
DTH1_k127_8860677_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005104 253.0
DTH1_k127_8860677_2 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000001257 115.0
DTH1_k127_8860677_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000001104 101.0
DTH1_k127_8862511_0 Transcriptional regulator, Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
DTH1_k127_8862511_1 Protein of unknown function DUF116 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 266.0
DTH1_k127_8862511_2 His Kinase A (phosphoacceptor) domain - - - 0.0002932 45.0
DTH1_k127_8899515_0 Acyl-CoA dehydrogenase N terminal K20035 - - 2.751e-244 764.0
DTH1_k127_8899515_1 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 425.0
DTH1_k127_8899515_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 404.0
DTH1_k127_8899515_3 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 393.0
DTH1_k127_8908875_0 Domain of unknown function (DUF4157) - - - 4.439e-246 791.0
DTH1_k127_8908875_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 400.0
DTH1_k127_8912586_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1046.0
DTH1_k127_8912586_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 608.0
DTH1_k127_8912586_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 482.0
DTH1_k127_8924760_0 Belongs to the malate synthase family K01638 - 2.3.3.9 1.107e-278 866.0
DTH1_k127_8924760_1 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 567.0
DTH1_k127_8924760_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
DTH1_k127_8924760_3 (ABC) transporter K05685,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
DTH1_k127_8924760_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000349 252.0
DTH1_k127_8930510_0 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 472.0
DTH1_k127_8930510_1 IS66 Orf2 like protein K07484 - - 0.00000000000000000000000000000000000000000000000000000008728 198.0
DTH1_k127_8930510_2 Transposase IS66 family - - - 0.00000000000000000000000000000000001142 141.0
DTH1_k127_8930510_3 Integrase - - - 0.00000000000000001297 84.0
DTH1_k127_8961919_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 6.239e-212 660.0
DTH1_k127_8961919_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000001603 236.0
DTH1_k127_8961919_2 Fe-S cluster K03616 - - 0.0000000000000000000000000000001226 130.0
DTH1_k127_8961919_3 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000002936 121.0
DTH1_k127_8975288_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 412.0
DTH1_k127_8975288_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
DTH1_k127_8975288_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000003281 192.0
DTH1_k127_8988427_0 Glycogen debranching enzyme - - - 0.0 1579.0
DTH1_k127_8988427_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
DTH1_k127_8988427_2 - - - - 0.00000000000000000000000000000000000000006623 160.0
DTH1_k127_8988427_3 Ion channel - - - 0.000000000000000000000000006671 113.0
DTH1_k127_9012671_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000001596 97.0
DTH1_k127_9012671_1 - - - - 0.00000002977 59.0
DTH1_k127_9012671_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.000579 49.0
DTH1_k127_9012790_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 493.0
DTH1_k127_9012790_1 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000002783 270.0
DTH1_k127_9012790_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000245 193.0
DTH1_k127_9032134_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 3.4e-256 803.0
DTH1_k127_9032134_1 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 437.0
DTH1_k127_9032134_2 Protein of unknown function (DUF1289) K06938 - - 0.0000000001049 64.0
DTH1_k127_90357_0 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 479.0
DTH1_k127_90357_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003038 259.0
DTH1_k127_90357_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005516 261.0
DTH1_k127_90357_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000001137 167.0
DTH1_k127_9041902_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 1.272e-268 838.0
DTH1_k127_9041902_1 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
DTH1_k127_9054667_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.113e-236 739.0
DTH1_k127_9054667_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 430.0
DTH1_k127_9054667_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 373.0
DTH1_k127_9054667_3 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000001832 107.0
DTH1_k127_9054667_4 Belongs to the peptidase S8 family - - - 0.0000000000002792 72.0
DTH1_k127_906077_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1052.0
DTH1_k127_906077_1 Thermostable hemolysin - - - 0.000000000000000000000000000000000000000000001242 173.0
DTH1_k127_906077_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000009103 163.0
DTH1_k127_906077_3 PFAM CHAD domain containing protein - - - 0.000000653 53.0
DTH1_k127_9070747_0 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 455.0
DTH1_k127_9070747_1 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 307.0
DTH1_k127_9072649_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 447.0
DTH1_k127_9072649_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000005261 180.0
DTH1_k127_9072649_2 - - - - 0.0000000000000000000000000000000000000003451 164.0
DTH1_k127_9080250_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
DTH1_k127_9080250_1 Signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000007705 199.0
DTH1_k127_9104242_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 530.0
DTH1_k127_9104242_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000008839 193.0
DTH1_k127_9110673_0 chain 5 L K00341 - 1.6.5.3 9.971e-300 933.0
DTH1_k127_9110673_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 507.0
DTH1_k127_9110673_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 301.0
DTH1_k127_9110673_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004359 272.0
DTH1_k127_9110673_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000003088 171.0
DTH1_k127_9110673_5 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.00000000001471 65.0
DTH1_k127_9110673_6 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000006157 55.0
DTH1_k127_9124317_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 561.0
DTH1_k127_916744_0 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 287.0
DTH1_k127_916744_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004383 268.0
DTH1_k127_916744_2 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000003504 184.0
DTH1_k127_916744_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000588 138.0
DTH1_k127_9178847_0 Sodium:solute symporter family - - - 6.102e-284 889.0
DTH1_k127_9178847_1 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 384.0
DTH1_k127_9178847_2 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000005619 157.0
DTH1_k127_9204238_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
DTH1_k127_9204238_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004834 274.0
DTH1_k127_9204238_2 Universal stress protein - - - 0.00000000000000000000000000000000001151 144.0
DTH1_k127_9204238_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000001165 123.0
DTH1_k127_9213221_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.828e-204 648.0
DTH1_k127_9213221_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000009488 217.0
DTH1_k127_9213221_2 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.000000000000000000004211 96.0
DTH1_k127_9215675_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 585.0
DTH1_k127_9215675_1 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 356.0
DTH1_k127_9215675_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
DTH1_k127_9215675_3 Protein of unknown function DUF45 K07043 - - 0.0000000001528 73.0
DTH1_k127_9237138_0 Iron-sulfur cluster-binding domain K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 555.0
DTH1_k127_9237138_1 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 463.0
DTH1_k127_9237138_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 389.0
DTH1_k127_9237138_3 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 350.0
DTH1_k127_9237138_4 Transport Permease Protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000152 284.0
DTH1_k127_9237138_5 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000116 248.0
DTH1_k127_9237138_6 Phasin protein - - - 0.000000000000000000000000000000000002402 145.0
DTH1_k127_9237138_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000001665 59.0
DTH1_k127_9238365_0 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 352.0
DTH1_k127_9238365_1 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 337.0
DTH1_k127_9258679_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 4.682e-212 662.0
DTH1_k127_9258679_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 487.0
DTH1_k127_9258679_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 406.0
DTH1_k127_9258679_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
DTH1_k127_9258679_4 transcriptional - - - 0.0000000000000000000000000000000000000000187 157.0
DTH1_k127_9258679_5 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000748 52.0
DTH1_k127_9263220_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 519.0
DTH1_k127_9263220_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 389.0
DTH1_k127_9263220_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004611 274.0
DTH1_k127_9263220_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
DTH1_k127_9277748_0 PQQ-like domain - - - 3.949e-315 967.0
DTH1_k127_9277748_1 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 450.0
DTH1_k127_9277748_2 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 382.0
DTH1_k127_9277748_3 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
DTH1_k127_9277748_4 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004521 250.0
DTH1_k127_9277748_5 - - - - 0.0000000000000000000000000000000000000000000000000000006431 203.0
DTH1_k127_9277748_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000002771 154.0
DTH1_k127_9277748_7 Cytochrome c - - - 0.00000000000000000000000000003808 132.0
DTH1_k127_9295149_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.396e-233 724.0
DTH1_k127_9295149_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 363.0
DTH1_k127_9295149_2 - - - - 0.0000000000000006124 79.0
DTH1_k127_9295149_3 His Kinase A (phospho-acceptor) domain - - - 0.00000000000005072 72.0
DTH1_k127_9320101_0 beta-galactosidase activity K01190 - 3.2.1.23 0.00000000003594 75.0
DTH1_k127_9372785_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 467.0
DTH1_k127_9372785_1 response to hydrogen peroxide K08985 - - 0.0000001104 61.0
DTH1_k127_9380468_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 379.0
DTH1_k127_9380468_1 PFAM Aminotransferase, class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 374.0
DTH1_k127_9380468_2 Iron-sulfur cluster assembly transcription factor IscR K13643 - - 0.000000000000000000000000000000000000000000000000000000000000001707 221.0
DTH1_k127_9380468_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000001595 165.0
DTH1_k127_9390301_0 Acts as a magnesium transporter K06213 - - 1.258e-209 661.0
DTH1_k127_9390301_1 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000005007 209.0
DTH1_k127_9391930_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.722e-271 842.0
DTH1_k127_9391930_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 502.0
DTH1_k127_9391930_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 475.0
DTH1_k127_9391930_3 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000001906 168.0
DTH1_k127_9391930_4 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000005323 128.0
DTH1_k127_9397332_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 482.0
DTH1_k127_9397332_1 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 377.0
DTH1_k127_9397332_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001692 255.0
DTH1_k127_9397332_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000009705 185.0
DTH1_k127_9397332_4 transcriptional - - - 0.0000000000000000000000000000000000000000000000006546 178.0
DTH1_k127_9400991_0 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 517.0
DTH1_k127_9400991_1 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 337.0
DTH1_k127_9400991_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 327.0
DTH1_k127_9404036_0 Membrane - - - 8.105e-221 694.0
DTH1_k127_9441998_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1253.0
DTH1_k127_9441998_1 - - - - 0.000000000000000000000002052 112.0
DTH1_k127_9441998_2 Modulates RecA activity K03565 - - 0.0000000001027 63.0
DTH1_k127_945006_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 583.0
DTH1_k127_945006_1 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004444 243.0
DTH1_k127_945006_2 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000002703 156.0
DTH1_k127_9451785_0 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001783 249.0
DTH1_k127_9451785_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000004219 211.0
DTH1_k127_9480463_0 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 267.0
DTH1_k127_9480463_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 250.0
DTH1_k127_9480463_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001532 237.0
DTH1_k127_9480463_3 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000000002105 174.0
DTH1_k127_9480463_4 methyltransferase activity - - - 0.000000000000000000000000000000005086 134.0
DTH1_k127_9480463_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000005789 127.0
DTH1_k127_9480463_6 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.0000000000000000000000000001757 125.0
DTH1_k127_9480463_7 HPP family K07168 - - 0.000000000000000000512 90.0
DTH1_k127_9480463_8 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000007851 91.0
DTH1_k127_9480463_9 - - - - 0.0000000001028 72.0
DTH1_k127_9490984_0 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 374.0
DTH1_k127_9490984_1 Hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009449 274.0
DTH1_k127_9490984_2 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000003272 172.0
DTH1_k127_9490984_3 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000001369 176.0
DTH1_k127_9490984_4 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000001744 63.0
DTH1_k127_9548777_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 529.0
DTH1_k127_9548777_1 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 454.0
DTH1_k127_9548777_10 malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.00000000000000002896 95.0
DTH1_k127_9548777_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 442.0
DTH1_k127_9548777_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 310.0
DTH1_k127_9548777_4 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000008973 264.0
DTH1_k127_9548777_5 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000006849 262.0
DTH1_k127_9548777_6 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
DTH1_k127_9548777_7 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.0000000000000000000000000000000000001355 147.0
DTH1_k127_9548777_8 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000002447 132.0
DTH1_k127_9548777_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000002562 97.0
DTH1_k127_9551426_0 Aminotransferase K01845 - 5.4.3.8 7.588e-214 670.0
DTH1_k127_9551426_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 544.0
DTH1_k127_9551426_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
DTH1_k127_9551426_3 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000001681 235.0
DTH1_k127_9558183_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1246.0
DTH1_k127_9558183_1 homoserine dehydrogenase K00003 - 1.1.1.3 7.614e-229 714.0
DTH1_k127_9558183_10 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000111 245.0
DTH1_k127_9558183_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000002504 237.0
DTH1_k127_9558183_12 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000009987 142.0
DTH1_k127_9558183_13 Putative diguanylate phosphodiesterase - - - 0.0000000000000001038 95.0
DTH1_k127_9558183_14 Signal Transduction Histidine Kinase - - - 0.0000000000009468 82.0
DTH1_k127_9558183_2 Threonine synthase K01733 - 4.2.3.1 5.516e-224 702.0
DTH1_k127_9558183_3 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 3.103e-221 694.0
DTH1_k127_9558183_4 Aminotransferase class I and II K14261 - - 2.565e-209 655.0
DTH1_k127_9558183_5 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 473.0
DTH1_k127_9558183_6 CoA-binding domain protein K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 359.0
DTH1_k127_9558183_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 355.0
DTH1_k127_9558183_8 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 311.0
DTH1_k127_9558183_9 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
DTH1_k127_9570666_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 383.0
DTH1_k127_9570666_1 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 360.0
DTH1_k127_9570666_2 NmrA-like family - - - 0.0000272 47.0
DTH1_k127_9574149_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 374.0
DTH1_k127_9574149_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 298.0
DTH1_k127_9574149_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000001882 243.0
DTH1_k127_9582454_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 7.256e-197 622.0
DTH1_k127_9582454_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 355.0
DTH1_k127_9582454_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
DTH1_k127_9582454_3 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000022 184.0
DTH1_k127_9582454_4 - - - - 0.0000002959 56.0
DTH1_k127_9589403_0 Multicopper oxidase K22349 - 1.16.3.3 2.805e-280 881.0
DTH1_k127_9589403_1 Multicopper oxidase K22349 - 1.16.3.3 1.481e-256 806.0
DTH1_k127_9589403_2 PFAM Ankyrin K10799 - 2.4.2.30 0.00000000004645 68.0
DTH1_k127_959538_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 2.137e-242 755.0
DTH1_k127_959538_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000003338 199.0
DTH1_k127_959538_2 KTSC domain - - - 0.000000000000000009446 85.0
DTH1_k127_959538_3 Archease protein family (MTH1598/TM1083) - - - 0.000000000000001004 77.0
DTH1_k127_9606682_0 ribonuclease, Rne Rng family K08301 - - 6.955e-233 739.0
DTH1_k127_9606682_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000575 271.0
DTH1_k127_9606682_2 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000005557 211.0
DTH1_k127_9606682_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000003086 115.0
DTH1_k127_9606682_4 DUF167 K09131 - - 0.00000000000000000000000006413 110.0
DTH1_k127_9606682_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000001398 65.0
DTH1_k127_9606933_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 529.0
DTH1_k127_9606933_1 L-cysteine cystine lyase K04127,K11325 - 5.1.1.17 0.00000000000000000000000000000000000000000000000002549 197.0
DTH1_k127_9606933_2 Telomere recombination K07566 - 2.7.7.87 0.0000004408 51.0
DTH1_k127_9628318_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.972e-196 620.0
DTH1_k127_9628318_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 440.0
DTH1_k127_9628318_10 response to antibiotic K07122 - - 0.0000000000000005701 89.0
DTH1_k127_9628318_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 422.0
DTH1_k127_9628318_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 400.0
DTH1_k127_9628318_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
DTH1_k127_9628318_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 352.0
DTH1_k127_9628318_6 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
DTH1_k127_9628318_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
DTH1_k127_9628318_8 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000002145 126.0
DTH1_k127_9628318_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000001007 101.0
DTH1_k127_9642301_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005451 282.0
DTH1_k127_9642301_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000003 262.0
DTH1_k127_9642301_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
DTH1_k127_9642301_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000007072 171.0
DTH1_k127_9642301_4 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000002155 132.0
DTH1_k127_9648739_0 acyl-CoA dehydrogenase K06445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 293.0
DTH1_k127_9648739_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
DTH1_k127_9648739_2 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 0.000000000000000000002043 95.0
DTH1_k127_9685284_0 Polysaccharide biosynthesis protein - - - 1.773e-255 800.0
DTH1_k127_9762411_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1080.0
DTH1_k127_9762411_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 608.0
DTH1_k127_9762411_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 469.0
DTH1_k127_9762411_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000002239 141.0
DTH1_k127_976736_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 511.0
DTH1_k127_976736_1 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 383.0
DTH1_k127_976736_2 FR47-like protein - - - 0.00000000000000000000000007456 111.0
DTH1_k127_9791601_0 acyl-CoA dehydrogenase K06445 - - 1.552e-268 839.0
DTH1_k127_9791601_1 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000005939 69.0
DTH1_k127_9794526_0 Cytochrome c oxidase, subunit K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 386.0
DTH1_k127_9794526_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 333.0
DTH1_k127_9796085_0 cytochrome - - - 1.679e-254 795.0
DTH1_k127_9796085_1 4Fe-4S single cluster domain - - - 8.715e-226 703.0
DTH1_k127_9796085_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 418.0
DTH1_k127_9796085_3 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
DTH1_k127_9796085_4 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000002492 214.0
DTH1_k127_9796085_5 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000003418 196.0
DTH1_k127_9814135_0 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 320.0
DTH1_k127_9814135_1 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000001187 167.0
DTH1_k127_9816653_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 582.0
DTH1_k127_9816653_1 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 477.0
DTH1_k127_9816653_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 411.0
DTH1_k127_9816653_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 334.0
DTH1_k127_9816653_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000005387 178.0
DTH1_k127_9826519_0 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000005958 168.0
DTH1_k127_9826519_1 Cysteine-rich secretory protein family - - - 0.000000002832 63.0
DTH1_k127_9836809_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 7.529e-201 638.0
DTH1_k127_9836809_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 508.0
DTH1_k127_9836809_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 304.0
DTH1_k127_9836809_3 metal cluster binding - - - 0.000000000000000000000000000003496 130.0
DTH1_k127_9836809_4 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000001799 108.0
DTH1_k127_9842573_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 301.0
DTH1_k127_9842573_1 Enoyl-(Acyl carrier protein) reductase K16066 - 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009088 277.0
DTH1_k127_9842573_2 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000001051 174.0
DTH1_k127_9843658_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
DTH1_k127_9843658_1 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000002442 240.0
DTH1_k127_9843658_2 - - - - 0.000000000000004295 84.0
DTH1_k127_9846414_0 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 293.0
DTH1_k127_9846414_1 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000001013 244.0
DTH1_k127_9846414_2 Transglycosylase associated protein - - - 0.00000000000000000000000000000000002119 136.0
DTH1_k127_9846414_3 ABC transporter transmembrane region K06147,K11004 - - 0.00000000003554 65.0
DTH1_k127_9850124_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 366.0
DTH1_k127_9850124_1 required for the transposition of insertion element IS2404 - - - 0.00000000000000000000000000000000004567 141.0
DTH1_k127_9850124_2 required for the transposition of insertion element IS2404 - - - 0.0000000000000000000000000002769 118.0
DTH1_k127_9850124_3 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000231 92.0
DTH1_k127_985284_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 560.0
DTH1_k127_985284_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 444.0
DTH1_k127_985284_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 333.0
DTH1_k127_985284_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000007054 107.0
DTH1_k127_9853621_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 5.368e-201 631.0
DTH1_k127_9853621_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 486.0
DTH1_k127_9853621_10 - - - - 0.0000000000007549 70.0
DTH1_k127_9853621_2 Major facilitator Superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 464.0
DTH1_k127_9853621_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 453.0
DTH1_k127_9853621_4 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 375.0
DTH1_k127_9853621_5 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007735 247.0
DTH1_k127_9853621_6 Dihydrofolate reductase K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000002668 195.0
DTH1_k127_9853621_7 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001372 139.0
DTH1_k127_9853621_8 TIR domain - - - 0.0000000000000000000000006021 118.0
DTH1_k127_9853621_9 Ammonium transporter K03320,K06580 - - 0.0000000000000000000002606 96.0
DTH1_k127_9860427_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 548.0
DTH1_k127_9860427_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 364.0
DTH1_k127_9860427_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 288.0
DTH1_k127_98909_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 556.0
DTH1_k127_9912044_0 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
DTH1_k127_9912044_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
DTH1_k127_9912044_2 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000001896 136.0
DTH1_k127_9912044_3 - - - - 0.0000007764 55.0
DTH1_k127_9958735_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 9.232e-231 719.0
DTH1_k127_9958735_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000000003538 138.0
DTH1_k127_9958735_2 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000003074 132.0
DTH1_k127_9958735_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000002364 91.0
DTH1_k127_9961351_0 alpha beta hydrolase fold K03821 - - 7.498e-246 771.0
DTH1_k127_9961351_1 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 540.0
DTH1_k127_9961351_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 512.0
DTH1_k127_9961351_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 460.0
DTH1_k127_9961351_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 321.0
DTH1_k127_9961351_5 Putative regulatory protein - - - 0.00000000000000000000000000001192 121.0
DTH1_k127_9961351_6 Type II secretion system protein B K02451 - - 0.0000000000000000006543 89.0
DTH1_k127_9967913_0 Transmembrane secretion effector - - - 1.348e-233 740.0
DTH1_k127_9967913_1 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000008724 145.0
DTH1_k127_99788_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.42e-302 939.0
DTH1_k127_99788_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 535.0
DTH1_k127_99788_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000002047 221.0
DTH1_k127_99788_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000008059 171.0
DTH1_k127_99788_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000006989 164.0
DTH1_k127_99788_5 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000000000004952 88.0