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Overview

ID MAG00756
Name DTH2_bin.10
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAKOQB01
Species
Assembly information
Completeness (%) 95.7
Contamination (%) 4.69
GC content (%) 64.0
N50 (bp) 49,216
Genome size (bp) 4,386,131

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4145

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10010668_0 Respiratory nitrate reductase beta C-terminal K00371,K17051 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 553.0
DTH2_k127_10010668_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 519.0
DTH2_k127_10010668_2 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
DTH2_k127_10010668_3 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000003467 176.0
DTH2_k127_10010668_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000005345 158.0
DTH2_k127_10010668_5 protein involved in response to NO K07234 - - 0.0000000004926 64.0
DTH2_k127_101762_0 DNA polymerase K00986 - 2.7.7.49 7.279e-204 644.0
DTH2_k127_101762_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 490.0
DTH2_k127_101762_10 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000004647 128.0
DTH2_k127_101762_11 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000001305 123.0
DTH2_k127_101762_12 - - - - 0.00000000000000000000000000003542 124.0
DTH2_k127_101762_13 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000002995 101.0
DTH2_k127_101762_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 465.0
DTH2_k127_101762_3 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 394.0
DTH2_k127_101762_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 289.0
DTH2_k127_101762_5 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
DTH2_k127_101762_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
DTH2_k127_101762_7 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000001383 193.0
DTH2_k127_101762_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000001736 169.0
DTH2_k127_101762_9 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000003375 139.0
DTH2_k127_1036063_0 Elements of external origin K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 313.0
DTH2_k127_1036063_1 Evidence 2b Function of strongly homologous gene K07497 - - 0.00000000000000000000000000000000000005938 144.0
DTH2_k127_12092_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 2103.0
DTH2_k127_12092_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1409.0
DTH2_k127_12092_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 511.0
DTH2_k127_12092_11 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 490.0
DTH2_k127_12092_12 beta' subunit K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 484.0
DTH2_k127_12092_13 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 481.0
DTH2_k127_12092_14 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 475.0
DTH2_k127_12092_15 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 470.0
DTH2_k127_12092_16 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 473.0
DTH2_k127_12092_17 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 437.0
DTH2_k127_12092_18 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 439.0
DTH2_k127_12092_19 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 403.0
DTH2_k127_12092_2 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1056.0
DTH2_k127_12092_20 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 406.0
DTH2_k127_12092_21 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 392.0
DTH2_k127_12092_22 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 400.0
DTH2_k127_12092_23 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 374.0
DTH2_k127_12092_24 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 374.0
DTH2_k127_12092_25 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 369.0
DTH2_k127_12092_26 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 342.0
DTH2_k127_12092_27 Stage II sporulation K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 351.0
DTH2_k127_12092_28 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 347.0
DTH2_k127_12092_29 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 314.0
DTH2_k127_12092_3 nitrite transporter K02575 - - 6.333e-308 949.0
DTH2_k127_12092_30 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 295.0
DTH2_k127_12092_31 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 307.0
DTH2_k127_12092_32 ABC-2 family transporter protein K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 298.0
DTH2_k127_12092_33 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
DTH2_k127_12092_34 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001318 280.0
DTH2_k127_12092_35 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
DTH2_k127_12092_36 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004608 289.0
DTH2_k127_12092_37 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 277.0
DTH2_k127_12092_38 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003547 272.0
DTH2_k127_12092_39 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
DTH2_k127_12092_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.096e-303 937.0
DTH2_k127_12092_40 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000597 260.0
DTH2_k127_12092_41 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000001094 260.0
DTH2_k127_12092_42 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
DTH2_k127_12092_43 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
DTH2_k127_12092_44 WHG domain - - - 0.000000000000000000000000000000000000000000000001516 181.0
DTH2_k127_12092_45 - - - - 0.00000000000000000000000000000000000000000003499 176.0
DTH2_k127_12092_46 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000003235 161.0
DTH2_k127_12092_47 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000006918 171.0
DTH2_k127_12092_48 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000872 130.0
DTH2_k127_12092_49 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000457 112.0
DTH2_k127_12092_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.308e-289 903.0
DTH2_k127_12092_50 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000001606 104.0
DTH2_k127_12092_51 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000002096 108.0
DTH2_k127_12092_52 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000013 115.0
DTH2_k127_12092_53 Histidine Phosphotransfer domain - - - 0.0000000000000000000001674 100.0
DTH2_k127_12092_54 Helix-hairpin-helix motif K02237 - - 0.0000000000000000002341 95.0
DTH2_k127_12092_55 Lipopolysaccharide assembly protein A domain K08992 - - 0.0001322 50.0
DTH2_k127_12092_6 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 2.578e-247 766.0
DTH2_k127_12092_7 Domain of Unknown Function (DUF748) - - - 5.443e-228 753.0
DTH2_k127_12092_8 Major Facilitator Superfamily K02575 - - 4.712e-211 665.0
DTH2_k127_12092_9 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 519.0
DTH2_k127_1245926_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1710.0
DTH2_k127_1245926_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.642e-251 782.0
DTH2_k127_1245926_10 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
DTH2_k127_1245926_11 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 296.0
DTH2_k127_1245926_12 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 234.0
DTH2_k127_1245926_13 FAD dependent oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000004746 238.0
DTH2_k127_1245926_14 intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000002681 159.0
DTH2_k127_1245926_15 LysM domain K08086 - - 0.0000000000000000000000000000000000000281 149.0
DTH2_k127_1245926_16 Alpha beta hydrolase - - - 0.000000000000000000000003131 105.0
DTH2_k127_1245926_17 Entericidin EcnA/B family - - - 0.000000007859 57.0
DTH2_k127_1245926_2 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 2.556e-240 759.0
DTH2_k127_1245926_3 o-acetylhomoserine K01740 - 2.5.1.49 5.692e-217 679.0
DTH2_k127_1245926_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 594.0
DTH2_k127_1245926_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 584.0
DTH2_k127_1245926_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 572.0
DTH2_k127_1245926_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 453.0
DTH2_k127_1245926_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 356.0
DTH2_k127_1245926_9 hydrolase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 332.0
DTH2_k127_1345057_0 FAD dependent oxidoreductase central domain - - - 0.0 1353.0
DTH2_k127_1345057_1 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 1.285e-311 990.0
DTH2_k127_1345057_10 alcohol dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 462.0
DTH2_k127_1345057_11 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 462.0
DTH2_k127_1345057_12 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 467.0
DTH2_k127_1345057_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 443.0
DTH2_k127_1345057_14 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 432.0
DTH2_k127_1345057_15 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 421.0
DTH2_k127_1345057_16 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 417.0
DTH2_k127_1345057_17 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 379.0
DTH2_k127_1345057_18 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 388.0
DTH2_k127_1345057_19 Membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
DTH2_k127_1345057_2 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 1.832e-258 816.0
DTH2_k127_1345057_20 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 329.0
DTH2_k127_1345057_21 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 325.0
DTH2_k127_1345057_22 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 321.0
DTH2_k127_1345057_23 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 342.0
DTH2_k127_1345057_24 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 314.0
DTH2_k127_1345057_25 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
DTH2_k127_1345057_26 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002786 273.0
DTH2_k127_1345057_27 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 267.0
DTH2_k127_1345057_28 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000005569 252.0
DTH2_k127_1345057_29 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000006004 229.0
DTH2_k127_1345057_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 4.317e-234 734.0
DTH2_k127_1345057_30 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000008171 220.0
DTH2_k127_1345057_31 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
DTH2_k127_1345057_32 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000000000006709 214.0
DTH2_k127_1345057_33 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000001134 191.0
DTH2_k127_1345057_34 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000002978 190.0
DTH2_k127_1345057_35 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000001492 177.0
DTH2_k127_1345057_36 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000918 171.0
DTH2_k127_1345057_37 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000005493 166.0
DTH2_k127_1345057_38 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000009249 171.0
DTH2_k127_1345057_39 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.000000000000000000000000000000000002377 150.0
DTH2_k127_1345057_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.719e-222 699.0
DTH2_k127_1345057_40 Multisubunit Na H antiporter, MnhG subunit K05564,K05571 - - 0.000000000000000000000000000008863 126.0
DTH2_k127_1345057_41 PFAM multiple resistance and pH regulation protein F K05563 - - 0.000000000000000000000001262 105.0
DTH2_k127_1345057_42 Protein of unknown function (DUF3429) - - - 0.000000000000000000002371 99.0
DTH2_k127_1345057_44 - - - - 0.0000000000001419 78.0
DTH2_k127_1345057_45 - - - - 0.000000000428 68.0
DTH2_k127_1345057_46 Protein of unknown function (DUF2934) - - - 0.0000004411 55.0
DTH2_k127_1345057_5 Peptidase M61 - - - 4.234e-214 681.0
DTH2_k127_1345057_6 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 547.0
DTH2_k127_1345057_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 527.0
DTH2_k127_1345057_8 flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 512.0
DTH2_k127_1345057_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
DTH2_k127_1363106_0 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 385.0
DTH2_k127_1363106_1 3',5'-cyclic-nucleotide phosphodiesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003172 242.0
DTH2_k127_1392153_0 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 317.0
DTH2_k127_1392153_1 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001189 277.0
DTH2_k127_1392153_2 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000005306 225.0
DTH2_k127_1392153_3 Flavin containing amine oxidoreductase K06955 - - 0.0000000000000000000000000000001515 140.0
DTH2_k127_1394092_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 434.0
DTH2_k127_1394092_1 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000002831 227.0
DTH2_k127_1403987_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 4.766e-269 849.0
DTH2_k127_1403987_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 2.35e-202 642.0
DTH2_k127_1403987_10 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 340.0
DTH2_k127_1403987_11 Pterin binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 334.0
DTH2_k127_1403987_12 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 305.0
DTH2_k127_1403987_13 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000006933 216.0
DTH2_k127_1403987_14 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000003744 189.0
DTH2_k127_1403987_15 system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000005919 153.0
DTH2_k127_1403987_16 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000001377 150.0
DTH2_k127_1403987_17 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000008521 155.0
DTH2_k127_1403987_18 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000001132 157.0
DTH2_k127_1403987_19 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000001736 143.0
DTH2_k127_1403987_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 517.0
DTH2_k127_1403987_20 PFAM Tol-Pal system TolA K03646 - - 0.00000000000000000000000008166 123.0
DTH2_k127_1403987_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 487.0
DTH2_k127_1403987_4 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 470.0
DTH2_k127_1403987_5 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 450.0
DTH2_k127_1403987_6 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 442.0
DTH2_k127_1403987_7 dioxygenase activity K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 401.0
DTH2_k127_1403987_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 393.0
DTH2_k127_1403987_9 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 372.0
DTH2_k127_1427712_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1857.0
DTH2_k127_1427712_1 Circularly permuted ATP-grasp type 2 - - - 2.602e-244 762.0
DTH2_k127_1427712_10 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 364.0
DTH2_k127_1427712_11 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 301.0
DTH2_k127_1427712_12 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
DTH2_k127_1427712_13 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000006358 189.0
DTH2_k127_1427712_14 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000001387 179.0
DTH2_k127_1427712_15 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000006393 139.0
DTH2_k127_1427712_16 Diguanylate cyclase - - - 0.0000000000000000000004903 108.0
DTH2_k127_1427712_17 COG0642 Signal transduction histidine kinase K20973 - 2.7.13.3 0.00000000000000003384 85.0
DTH2_k127_1427712_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.517e-215 683.0
DTH2_k127_1427712_3 Competence protein K02238 - - 5.745e-195 636.0
DTH2_k127_1427712_4 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 599.0
DTH2_k127_1427712_5 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 594.0
DTH2_k127_1427712_6 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 558.0
DTH2_k127_1427712_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 563.0
DTH2_k127_1427712_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 526.0
DTH2_k127_1427712_9 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 451.0
DTH2_k127_1429346_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1742.0
DTH2_k127_1429346_1 Histidine kinase-like ATPases - - - 0.0 1112.0
DTH2_k127_1429346_10 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 305.0
DTH2_k127_1429346_11 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007748 281.0
DTH2_k127_1429346_12 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001208 248.0
DTH2_k127_1429346_13 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000049 110.0
DTH2_k127_1429346_14 Histidine kinase K20976 - - 0.00000000000000000003176 94.0
DTH2_k127_1429346_15 - - - - 0.000000000005243 72.0
DTH2_k127_1429346_2 AMP-binding enzyme C-terminal domain K02182,K20034 GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044464,GO:0071704 6.2.1.44,6.2.1.48 8.098e-278 862.0
DTH2_k127_1429346_3 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 610.0
DTH2_k127_1429346_4 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 518.0
DTH2_k127_1429346_5 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 514.0
DTH2_k127_1429346_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 438.0
DTH2_k127_1429346_7 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 429.0
DTH2_k127_1429346_8 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 371.0
DTH2_k127_1429346_9 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 329.0
DTH2_k127_1505778_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2361.0
DTH2_k127_1505778_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2296.0
DTH2_k127_1505778_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1232.0
DTH2_k127_1505778_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007039 274.0
DTH2_k127_1505778_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 230.0
DTH2_k127_1505778_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000002726 87.0
DTH2_k127_1543727_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.35e-279 864.0
DTH2_k127_1543727_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 589.0
DTH2_k127_1543727_10 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
DTH2_k127_1543727_11 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 305.0
DTH2_k127_1543727_12 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001117 250.0
DTH2_k127_1543727_13 PFAM ribulose bisphosphate carboxylase small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000003009 226.0
DTH2_k127_1543727_14 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000002028 169.0
DTH2_k127_1543727_15 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000009299 163.0
DTH2_k127_1543727_16 Phospholipid methyltransferase - - - 0.0000000000000000002513 98.0
DTH2_k127_1543727_2 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 583.0
DTH2_k127_1543727_3 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 541.0
DTH2_k127_1543727_4 Phosphoribulokinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 487.0
DTH2_k127_1543727_5 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 445.0
DTH2_k127_1543727_6 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 441.0
DTH2_k127_1543727_7 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 436.0
DTH2_k127_1543727_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 413.0
DTH2_k127_1543727_9 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 306.0
DTH2_k127_1554253_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.197e-265 836.0
DTH2_k127_1554253_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K03299 - - 7.879e-257 803.0
DTH2_k127_1554253_10 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 336.0
DTH2_k127_1554253_11 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 294.0
DTH2_k127_1554253_12 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008027 272.0
DTH2_k127_1554253_13 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
DTH2_k127_1554253_14 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000001024 217.0
DTH2_k127_1554253_15 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
DTH2_k127_1554253_16 PAC sensor-containing diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000002262 191.0
DTH2_k127_1554253_17 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000008425 165.0
DTH2_k127_1554253_18 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000003361 147.0
DTH2_k127_1554253_19 Group II intron, maturase-specific domain - - - 0.00000000000000000000000000000000002103 135.0
DTH2_k127_1554253_2 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 8.864e-203 639.0
DTH2_k127_1554253_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 582.0
DTH2_k127_1554253_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 547.0
DTH2_k127_1554253_5 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 535.0
DTH2_k127_1554253_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 531.0
DTH2_k127_1554253_7 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 470.0
DTH2_k127_1554253_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 375.0
DTH2_k127_1554253_9 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 371.0
DTH2_k127_1583613_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.293e-234 737.0
DTH2_k127_1583613_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 522.0
DTH2_k127_1583613_2 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 469.0
DTH2_k127_1583613_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 298.0
DTH2_k127_1583613_4 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002191 253.0
DTH2_k127_1583613_5 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
DTH2_k127_1583613_6 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000105 200.0
DTH2_k127_1583613_7 Endoribonuclease L-PSP K10013 - - 0.0000000000000000000000000000000000000000000000005627 179.0
DTH2_k127_1583613_8 UPF0126 domain - - - 0.0000000489 56.0
DTH2_k127_1591458_0 PFAM extracellular solute-binding protein family 1 K05813 - - 1.032e-236 749.0
DTH2_k127_1591458_1 Pilus retraction K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 582.0
DTH2_k127_1591458_10 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001098 252.0
DTH2_k127_1591458_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000001709 190.0
DTH2_k127_1591458_13 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000004691 104.0
DTH2_k127_1591458_2 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 582.0
DTH2_k127_1591458_3 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 494.0
DTH2_k127_1591458_4 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 462.0
DTH2_k127_1591458_5 THUMP domain K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 436.0
DTH2_k127_1591458_6 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 357.0
DTH2_k127_1591458_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
DTH2_k127_1591458_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 280.0
DTH2_k127_1591458_9 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000601 275.0
DTH2_k127_1614795_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1020.0
DTH2_k127_1614795_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1019.0
DTH2_k127_1614795_10 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 525.0
DTH2_k127_1614795_11 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 537.0
DTH2_k127_1614795_12 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 496.0
DTH2_k127_1614795_13 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 475.0
DTH2_k127_1614795_14 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 443.0
DTH2_k127_1614795_15 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 434.0
DTH2_k127_1614795_16 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 418.0
DTH2_k127_1614795_17 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 418.0
DTH2_k127_1614795_18 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 412.0
DTH2_k127_1614795_19 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 398.0
DTH2_k127_1614795_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1014.0
DTH2_k127_1614795_20 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 357.0
DTH2_k127_1614795_21 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
DTH2_k127_1614795_22 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000321 286.0
DTH2_k127_1614795_23 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 293.0
DTH2_k127_1614795_24 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001189 287.0
DTH2_k127_1614795_25 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000278 265.0
DTH2_k127_1614795_26 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 256.0
DTH2_k127_1614795_27 lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001874 252.0
DTH2_k127_1614795_28 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000002599 244.0
DTH2_k127_1614795_29 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003643 245.0
DTH2_k127_1614795_3 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 2.82e-288 918.0
DTH2_k127_1614795_30 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001126 241.0
DTH2_k127_1614795_31 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
DTH2_k127_1614795_32 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
DTH2_k127_1614795_33 Haem-degrading K11477 - - 0.000000000000000000000000000000000000000000000000000002238 195.0
DTH2_k127_1614795_34 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001242 201.0
DTH2_k127_1614795_35 DUF218 domain - - - 0.00000000000000000000000000000000000000000000001783 181.0
DTH2_k127_1614795_36 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000001277 171.0
DTH2_k127_1614795_37 NLP P60 protein - - - 0.0000000000000000000000000000000000000002 158.0
DTH2_k127_1614795_38 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000002889 156.0
DTH2_k127_1614795_39 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000002406 153.0
DTH2_k127_1614795_4 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 2.435e-278 866.0
DTH2_k127_1614795_40 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000009548 147.0
DTH2_k127_1614795_41 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000009058 143.0
DTH2_k127_1614795_42 membrane - - - 0.0000000000000000000000000000000000008998 150.0
DTH2_k127_1614795_43 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000546 113.0
DTH2_k127_1614795_44 - - - - 0.000000000000000000002553 99.0
DTH2_k127_1614795_45 TM2 domain - - - 0.000000000000000000003841 97.0
DTH2_k127_1614795_46 Protein conserved in bacteria K09705 - - 0.000000001124 66.0
DTH2_k127_1614795_47 PFAM RDD domain containing protein - - - 0.0000001832 57.0
DTH2_k127_1614795_5 PFAM AMP-dependent synthetase and ligase K00666 - - 1.074e-270 842.0
DTH2_k127_1614795_6 Cysteine-rich domain - - - 5.65e-212 666.0
DTH2_k127_1614795_7 Oxidoreductase - - - 3.888e-208 659.0
DTH2_k127_1614795_8 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 620.0
DTH2_k127_1614795_9 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 548.0
DTH2_k127_1614962_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1317.0
DTH2_k127_1614962_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 596.0
DTH2_k127_1614962_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 608.0
DTH2_k127_1614962_3 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 350.0
DTH2_k127_1614962_4 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 322.0
DTH2_k127_1614962_5 Tat pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 252.0
DTH2_k127_1614962_6 Tat pathway signal - - - 0.000000000000000000000000000000000000000000000000000000000000002441 241.0
DTH2_k127_1614962_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000001624 184.0
DTH2_k127_1614962_8 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000004701 163.0
DTH2_k127_1614962_9 Protein of unknown function (DUF1800) - - - 0.00000294 51.0
DTH2_k127_1634200_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 8.534e-282 876.0
DTH2_k127_1634200_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 1.118e-273 853.0
DTH2_k127_1634200_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.452e-231 729.0
DTH2_k127_1634200_3 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 347.0
DTH2_k127_1634200_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001745 281.0
DTH2_k127_1634200_5 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007522 250.0
DTH2_k127_1634200_6 TonB C terminal - - - 0.00000000000000000000000000000009072 139.0
DTH2_k127_1634200_7 - - - - 0.0000001665 58.0
DTH2_k127_1637923_0 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
DTH2_k127_1637923_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000001354 239.0
DTH2_k127_1637923_2 Gram-negative porin - - - 0.000000000000000000033 103.0
DTH2_k127_1658347_0 MMPL family K03296,K18138,K18902 - - 1.062e-208 664.0
DTH2_k127_1658347_1 Extracellular ligand-binding receptor K01999 - - 1.286e-202 637.0
DTH2_k127_1658347_10 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002717 262.0
DTH2_k127_1658347_11 Lysozyme inhibitor LprI - - - 0.00000000000000000000000000000000000000000000000000000000000009244 228.0
DTH2_k127_1658347_12 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000007056 212.0
DTH2_k127_1658347_13 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000000006058 216.0
DTH2_k127_1658347_14 - - - - 0.000000000000000000000000000000000000000000003455 177.0
DTH2_k127_1658347_15 - - - - 0.00000000000000000000000000000000255 144.0
DTH2_k127_1658347_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 6.834e-200 637.0
DTH2_k127_1658347_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 496.0
DTH2_k127_1658347_4 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 499.0
DTH2_k127_1658347_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 474.0
DTH2_k127_1658347_6 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 447.0
DTH2_k127_1658347_7 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 413.0
DTH2_k127_1658347_8 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 363.0
DTH2_k127_1658347_9 RND efflux system, outer membrane lipoprotein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 339.0
DTH2_k127_1659654_0 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 501.0
DTH2_k127_1659654_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 292.0
DTH2_k127_1659654_2 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000445 179.0
DTH2_k127_1659654_3 LysM domain - - - 0.00000000002976 66.0
DTH2_k127_1686300_0 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 382.0
DTH2_k127_1686300_1 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000000000000000000000000000000000000000000168 228.0
DTH2_k127_1686300_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000008832 223.0
DTH2_k127_1686300_3 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000003346 217.0
DTH2_k127_1686300_4 - - - - 0.00000000000000000000000000000000000000000000000000002043 194.0
DTH2_k127_1686300_5 glutamate--cysteine ligase - - - 0.00000000000000000000000000000006071 136.0
DTH2_k127_1686300_6 transcription regulator containing HTH domain K18831 - - 0.000000000000000000000000001586 117.0
DTH2_k127_1686300_7 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system - - - 0.000000000000000000000001154 106.0
DTH2_k127_1686300_8 Protein of unknown function (DUF2788) - - - 0.000000000000000000000005637 104.0
DTH2_k127_1686300_9 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0001563 55.0
DTH2_k127_1798039_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.561e-235 744.0
DTH2_k127_1798039_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 569.0
DTH2_k127_1798039_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 543.0
DTH2_k127_1798039_3 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 526.0
DTH2_k127_1798039_4 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 297.0
DTH2_k127_1798039_5 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000003715 200.0
DTH2_k127_1798039_6 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000008489 169.0
DTH2_k127_1798039_7 Pfam O-Antigen Polymerase - - - 0.0000000000000000000000000000000002013 151.0
DTH2_k127_1798039_8 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000001431 116.0
DTH2_k127_1803408_0 Protein of unknown function (DUF2726) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
DTH2_k127_1803408_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002481 277.0
DTH2_k127_1803408_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000001872 146.0
DTH2_k127_1803408_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000003776 116.0
DTH2_k127_1832392_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 8.5e-284 899.0
DTH2_k127_1832392_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.597e-199 630.0
DTH2_k127_1832392_10 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000036 250.0
DTH2_k127_1832392_11 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000012 241.0
DTH2_k127_1832392_12 SpoU rRNA Methylase family K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000001109 232.0
DTH2_k127_1832392_13 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000002016 224.0
DTH2_k127_1832392_14 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000002526 155.0
DTH2_k127_1832392_15 peptidyl-prolyl K03775 - 5.2.1.8 0.000000000000000000000000000000000004699 143.0
DTH2_k127_1832392_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001617 143.0
DTH2_k127_1832392_17 - - - - 0.00000000498 65.0
DTH2_k127_1832392_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 617.0
DTH2_k127_1832392_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 559.0
DTH2_k127_1832392_4 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 389.0
DTH2_k127_1832392_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
DTH2_k127_1832392_6 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 372.0
DTH2_k127_1832392_7 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 349.0
DTH2_k127_1832392_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 325.0
DTH2_k127_1832392_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000154 274.0
DTH2_k127_1856341_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000001429 198.0
DTH2_k127_1859325_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 5.814e-262 813.0
DTH2_k127_1859325_1 Bacterial extracellular solute-binding protein K02027 - - 3.733e-220 689.0
DTH2_k127_1859325_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 472.0
DTH2_k127_1859325_12 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 455.0
DTH2_k127_1859325_13 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 443.0
DTH2_k127_1859325_14 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 421.0
DTH2_k127_1859325_15 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 398.0
DTH2_k127_1859325_16 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 393.0
DTH2_k127_1859325_17 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 396.0
DTH2_k127_1859325_18 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 367.0
DTH2_k127_1859325_19 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 363.0
DTH2_k127_1859325_2 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 6.372e-211 659.0
DTH2_k127_1859325_20 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 349.0
DTH2_k127_1859325_21 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 344.0
DTH2_k127_1859325_22 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 309.0
DTH2_k127_1859325_23 YaeQ family - - - 0.0000000000000000000000000000000000000000000000000000000000000007568 223.0
DTH2_k127_1859325_24 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000005938 194.0
DTH2_k127_1859325_25 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001513 194.0
DTH2_k127_1859325_26 PFAM FMN-binding domain - - - 0.0000000000000000000000000008773 125.0
DTH2_k127_1859325_27 Plasmid stabilization system K19092 - - 0.00000000000000000000000000165 115.0
DTH2_k127_1859325_28 Phosphopantetheine attachment site - - - 0.00000000000000000004633 101.0
DTH2_k127_1859325_29 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.000000000000005339 76.0
DTH2_k127_1859325_3 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 1.826e-201 632.0
DTH2_k127_1859325_30 NADH pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.000000008318 59.0
DTH2_k127_1859325_31 Cytochrome c - - - 0.00000006263 54.0
DTH2_k127_1859325_32 nadh pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 0.00000006877 57.0
DTH2_k127_1859325_33 Cytochrome c - - - 0.0000005936 57.0
DTH2_k127_1859325_34 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000001378 53.0
DTH2_k127_1859325_35 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000748 52.0
DTH2_k127_1859325_4 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 573.0
DTH2_k127_1859325_5 PFAM Prokaryotic protein of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 541.0
DTH2_k127_1859325_6 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 540.0
DTH2_k127_1859325_7 ABC-type sugar K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 497.0
DTH2_k127_1859325_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 496.0
DTH2_k127_1859325_9 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 490.0
DTH2_k127_1878746_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 373.0
DTH2_k127_1878746_1 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
DTH2_k127_1878746_2 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002849 245.0
DTH2_k127_1878746_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000001511 214.0
DTH2_k127_1908711_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.289e-266 830.0
DTH2_k127_1908711_1 Cytochrome b(N-terminal)/b6/petB - - - 2.876e-231 732.0
DTH2_k127_1908711_2 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 292.0
DTH2_k127_1908711_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
DTH2_k127_1908711_4 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001252 252.0
DTH2_k127_1908711_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000002995 180.0
DTH2_k127_1908711_6 Invasion gene expression up-regulator SirB - - - 0.00000000000000000000000000007933 119.0
DTH2_k127_1908711_7 - - - - 0.000000000009105 68.0
DTH2_k127_1927890_0 FAD dependent oxidoreductase K13796 - - 2.349e-233 728.0
DTH2_k127_1927890_1 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 1.06e-214 677.0
DTH2_k127_1927890_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000002033 181.0
DTH2_k127_1927890_11 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000000000007145 159.0
DTH2_k127_1927890_12 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000001314 147.0
DTH2_k127_1927890_13 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000005483 130.0
DTH2_k127_1927890_14 - - - - 0.00000000000001105 85.0
DTH2_k127_1927890_15 Peptidase propeptide and YPEB domain - - - 0.00000000003364 69.0
DTH2_k127_1927890_2 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 552.0
DTH2_k127_1927890_3 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 396.0
DTH2_k127_1927890_4 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 301.0
DTH2_k127_1927890_5 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
DTH2_k127_1927890_6 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000000000000000000000000000004601 221.0
DTH2_k127_1927890_7 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000000000001003 195.0
DTH2_k127_1927890_8 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000001627 179.0
DTH2_k127_1927890_9 CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000002031 172.0
DTH2_k127_1954490_0 Efflux pump membrane transporter K18138 - - 0.0 1396.0
DTH2_k127_1954490_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 557.0
DTH2_k127_1954490_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 543.0
DTH2_k127_1954490_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 527.0
DTH2_k127_1954490_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 411.0
DTH2_k127_1954490_5 rhamnose metabolic process - - - 0.0000000000000000000000000000000001711 134.0
DTH2_k127_2083678_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 361.0
DTH2_k127_2083678_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 287.0
DTH2_k127_2083678_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000001008 201.0
DTH2_k127_2083678_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000002831 196.0
DTH2_k127_2083678_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000388 157.0
DTH2_k127_2083678_5 - - - - 0.000000000000000002451 89.0
DTH2_k127_208453_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 9.124e-239 745.0
DTH2_k127_208453_1 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.841e-225 701.0
DTH2_k127_208453_10 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 517.0
DTH2_k127_208453_11 periplasmic K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 483.0
DTH2_k127_208453_12 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 495.0
DTH2_k127_208453_13 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 461.0
DTH2_k127_208453_14 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
DTH2_k127_208453_15 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 386.0
DTH2_k127_208453_16 Pfam Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
DTH2_k127_208453_17 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 359.0
DTH2_k127_208453_18 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 336.0
DTH2_k127_208453_19 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 324.0
DTH2_k127_208453_2 Trap dicarboxylate transporter, dctm subunit - - - 1.36e-223 698.0
DTH2_k127_208453_20 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 321.0
DTH2_k127_208453_21 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002986 270.0
DTH2_k127_208453_22 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000136 248.0
DTH2_k127_208453_23 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001523 252.0
DTH2_k127_208453_24 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 240.0
DTH2_k127_208453_25 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
DTH2_k127_208453_26 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000001761 207.0
DTH2_k127_208453_27 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000001047 203.0
DTH2_k127_208453_28 Plasmid stabilization system K19092 - - 0.000000000000000000000000000000000000000007529 159.0
DTH2_k127_208453_29 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000003511 148.0
DTH2_k127_208453_3 MmgE PrpD family protein - - - 2.279e-208 656.0
DTH2_k127_208453_30 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000001566 126.0
DTH2_k127_208453_31 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000003324 127.0
DTH2_k127_208453_32 Dodecin K09165 - - 0.00000000000000000000000000006342 118.0
DTH2_k127_208453_33 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000015 115.0
DTH2_k127_208453_34 - - - - 0.00000000000000000000002326 108.0
DTH2_k127_208453_35 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000004486 91.0
DTH2_k127_208453_36 mRNA binding K07339 - - 0.000000000000000002989 89.0
DTH2_k127_208453_37 Domain of unknown function (DUF4160) - - - 0.000000000000000008231 84.0
DTH2_k127_208453_38 Protein of unknown function (DUF2442) - - - 0.00000000000001376 77.0
DTH2_k127_208453_39 Domain of unknown function (DUF4160) - - - 0.0000001962 52.0
DTH2_k127_208453_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 9.265e-208 654.0
DTH2_k127_208453_40 - - - - 0.0000002482 55.0
DTH2_k127_208453_41 protein import - - - 0.00001675 50.0
DTH2_k127_208453_42 - - - - 0.00002289 54.0
DTH2_k127_208453_5 CoA-transferase family III K18289 - 2.8.3.22 6.56e-196 627.0
DTH2_k127_208453_6 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 582.0
DTH2_k127_208453_7 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 578.0
DTH2_k127_208453_8 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 583.0
DTH2_k127_208453_9 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 562.0
DTH2_k127_2096085_0 Methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 561.0
DTH2_k127_2096085_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 349.0
DTH2_k127_2146646_0 Acyl-CoA dehydrogenase, middle domain - - - 1.552e-213 668.0
DTH2_k127_2146646_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 591.0
DTH2_k127_2146646_10 GYD domain - - - 0.00000000000000000000000000001804 120.0
DTH2_k127_2146646_11 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000000002389 105.0
DTH2_k127_2146646_12 - - - - 0.000000000000000009693 87.0
DTH2_k127_2146646_13 Belongs to the peptidase S1C family - - - 0.0000000005909 65.0
DTH2_k127_2146646_14 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000009119 59.0
DTH2_k127_2146646_15 Tripartite tricarboxylate transporter family receptor - - - 0.0001373 48.0
DTH2_k127_2146646_17 Protein of unknown function (DUF3617) - - - 0.0002138 50.0
DTH2_k127_2146646_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 344.0
DTH2_k127_2146646_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
DTH2_k127_2146646_4 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000002499 218.0
DTH2_k127_2146646_5 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000009851 179.0
DTH2_k127_2146646_6 - - - - 0.000000000000000000000000000000000000002862 151.0
DTH2_k127_2146646_7 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000000000000341 144.0
DTH2_k127_2146646_8 Plasmid stabilization system K19092 - - 0.00000000000000000000000000000000000004428 145.0
DTH2_k127_2146646_9 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000003833 153.0
DTH2_k127_2243413_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 580.0
DTH2_k127_2243413_1 Ketopantoate hydroxymethyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 497.0
DTH2_k127_2243413_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000001103 197.0
DTH2_k127_2243413_11 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - GO:0003674,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008270,GO:0015711,GO:0015718,GO:0015727,GO:0015849,GO:0015850,GO:0031317,GO:0032991,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046942,GO:0046983,GO:0051179,GO:0051234,GO:0071702,GO:1990351 - 0.000000000000000000000000000000000000000000000000004572 191.0
DTH2_k127_2243413_2 Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 374.0
DTH2_k127_2243413_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 376.0
DTH2_k127_2243413_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 354.0
DTH2_k127_2243413_5 TRAP dicarboxylate transporter, DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 314.0
DTH2_k127_2243413_6 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004348 267.0
DTH2_k127_2243413_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000005777 239.0
DTH2_k127_2243413_8 COG1145 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000001722 212.0
DTH2_k127_2243413_9 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000005089 215.0
DTH2_k127_2295863_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 557.0
DTH2_k127_2295863_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 358.0
DTH2_k127_2295863_10 - - - - 0.0000000000000000000001476 102.0
DTH2_k127_2295863_11 - - - - 0.00000000000000004343 87.0
DTH2_k127_2295863_12 carboxylic ester hydrolase activity K03929 - - 0.0000000003465 68.0
DTH2_k127_2295863_13 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000005564 55.0
DTH2_k127_2295863_15 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0009726 42.0
DTH2_k127_2295863_2 Diguanylate cyclase K13069 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0008270,GO:0009987,GO:0010639,GO:0016740,GO:0016772,GO:0016779,GO:0022610,GO:0031344,GO:0031345,GO:0031589,GO:0032879,GO:0033043,GO:0042710,GO:0042802,GO:0043167,GO:0043169,GO:0043708,GO:0043709,GO:0043900,GO:0043902,GO:0044010,GO:0044087,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0060187,GO:0060491,GO:0065007,GO:0090605,GO:0090609,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1902115,GO:1902116,GO:1902208,GO:1902209 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
DTH2_k127_2295863_3 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000006081 239.0
DTH2_k127_2295863_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
DTH2_k127_2295863_5 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000576 188.0
DTH2_k127_2295863_6 plasmid maintenance system antidote protein K21498 - - 0.0000000000000000000000000000000000000000001166 160.0
DTH2_k127_2295863_7 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000001006 140.0
DTH2_k127_2295863_8 protein conserved in bacteria - - - 0.00000000000000000000000000000002673 130.0
DTH2_k127_2295863_9 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000002407 110.0
DTH2_k127_2530251_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 5.327e-221 704.0
DTH2_k127_2530251_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001382 205.0
DTH2_k127_2530251_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000001234 185.0
DTH2_k127_2530251_3 ASCH - - - 0.000000000000000000000000000000000001234 145.0
DTH2_k127_2530251_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000005617 141.0
DTH2_k127_2530251_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000002548 132.0
DTH2_k127_2535414_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1669.0
DTH2_k127_2535414_1 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1068.0
DTH2_k127_2535414_10 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 339.0
DTH2_k127_2535414_11 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 301.0
DTH2_k127_2535414_12 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004112 269.0
DTH2_k127_2535414_13 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001494 258.0
DTH2_k127_2535414_14 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002955 264.0
DTH2_k127_2535414_15 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002757 232.0
DTH2_k127_2535414_16 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000004188 218.0
DTH2_k127_2535414_17 - - - - 0.000000000000000000000000000000000000000000000000000008685 193.0
DTH2_k127_2535414_18 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000001912 185.0
DTH2_k127_2535414_19 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000001108 162.0
DTH2_k127_2535414_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 1.009e-220 705.0
DTH2_k127_2535414_20 DsrC like protein K11179 - - 0.00000000000000000000000000000000000001407 151.0
DTH2_k127_2535414_21 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000000000002702 144.0
DTH2_k127_2535414_22 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000003743 107.0
DTH2_k127_2535414_23 - - - - 0.00000000000000000000001452 109.0
DTH2_k127_2535414_24 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000002132 89.0
DTH2_k127_2535414_25 - - - - 0.00000000001579 68.0
DTH2_k127_2535414_3 PUA-like domain K00958 - 2.7.7.4 2.943e-214 672.0
DTH2_k127_2535414_4 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 565.0
DTH2_k127_2535414_5 binding domain K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 520.0
DTH2_k127_2535414_6 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 486.0
DTH2_k127_2535414_7 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
DTH2_k127_2535414_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 432.0
DTH2_k127_2535414_9 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 398.0
DTH2_k127_2561113_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1279.0
DTH2_k127_2561113_1 DNA helicase K03657 - 3.6.4.12 1.148e-279 895.0
DTH2_k127_2561113_10 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 391.0
DTH2_k127_2561113_11 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 385.0
DTH2_k127_2561113_12 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
DTH2_k127_2561113_13 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 373.0
DTH2_k127_2561113_14 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 340.0
DTH2_k127_2561113_15 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 333.0
DTH2_k127_2561113_16 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 336.0
DTH2_k127_2561113_17 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 331.0
DTH2_k127_2561113_18 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 289.0
DTH2_k127_2561113_19 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005018 267.0
DTH2_k127_2561113_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 9.042e-238 740.0
DTH2_k127_2561113_20 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000000000000002266 212.0
DTH2_k127_2561113_21 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000002385 158.0
DTH2_k127_2561113_22 Multicopper oxidase - - - 0.000000000000000000000000000000000000001928 166.0
DTH2_k127_2561113_23 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000002444 141.0
DTH2_k127_2561113_24 - - - - 0.00000000000000000000000000009869 125.0
DTH2_k127_2561113_25 Ion channel - - - 0.00000000000000000000001509 105.0
DTH2_k127_2561113_26 Peptidase family M1 domain - - - 0.00000000000000002101 88.0
DTH2_k127_2561113_27 Protein of unknown function (DUF1800) - - - 0.000000002709 63.0
DTH2_k127_2561113_3 Putative modulator of DNA gyrase - - - 2.427e-200 634.0
DTH2_k127_2561113_4 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 527.0
DTH2_k127_2561113_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 539.0
DTH2_k127_2561113_6 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 533.0
DTH2_k127_2561113_7 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 471.0
DTH2_k127_2561113_8 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 457.0
DTH2_k127_2561113_9 Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 401.0
DTH2_k127_2570823_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 3.05e-251 777.0
DTH2_k127_2570823_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 445.0
DTH2_k127_2619183_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1400.0
DTH2_k127_2619183_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1380.0
DTH2_k127_2619183_10 branched-chain amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 477.0
DTH2_k127_2619183_11 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 472.0
DTH2_k127_2619183_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 441.0
DTH2_k127_2619183_13 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 425.0
DTH2_k127_2619183_14 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 297.0
DTH2_k127_2619183_15 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 299.0
DTH2_k127_2619183_16 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000004277 218.0
DTH2_k127_2619183_17 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.00000000000000000000000000000000000000000000000000000000002294 210.0
DTH2_k127_2619183_18 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000223 166.0
DTH2_k127_2619183_19 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000009993 70.0
DTH2_k127_2619183_2 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1200.0
DTH2_k127_2619183_20 AAA domain - - - 0.00000000000269 69.0
DTH2_k127_2619183_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0 1033.0
DTH2_k127_2619183_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 4.592e-307 953.0
DTH2_k127_2619183_5 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 6.284e-286 890.0
DTH2_k127_2619183_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 4.02e-219 690.0
DTH2_k127_2619183_7 Belongs to the thiolase family - - - 1.398e-211 663.0
DTH2_k127_2619183_8 CoA-transferase family III - - - 2.103e-208 659.0
DTH2_k127_2619183_9 COG1960 Acyl-CoA dehydrogenases - - - 1.214e-197 623.0
DTH2_k127_2623597_0 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 552.0
DTH2_k127_2623597_1 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 410.0
DTH2_k127_2623597_2 Asp/Glu/Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 377.0
DTH2_k127_2623597_3 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000004035 154.0
DTH2_k127_2708269_0 ABC transporter transmembrane region K06147,K18893 - - 8.633e-271 841.0
DTH2_k127_2708269_1 Luciferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 469.0
DTH2_k127_2708269_10 Putative transposase - - - 0.000000000001728 80.0
DTH2_k127_2708269_11 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00480 - 1.14.13.1 0.000000001292 61.0
DTH2_k127_2708269_2 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 469.0
DTH2_k127_2708269_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 308.0
DTH2_k127_2708269_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001237 217.0
DTH2_k127_2708269_5 Belongs to the peptidase S11 family K07258,K07262 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.000000000000000000000000000000000000000000000000000001601 203.0
DTH2_k127_2708269_6 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000005488 201.0
DTH2_k127_2708269_7 chain release factor K15034 - - 0.0000000000000000000000000000000000000000000000001547 180.0
DTH2_k127_2708269_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000007508 120.0
DTH2_k127_2708269_9 SpoVT / AbrB like domain - - - 0.00000000000001464 76.0
DTH2_k127_2708271_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 392.0
DTH2_k127_2708271_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 385.0
DTH2_k127_2708271_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000001093 130.0
DTH2_k127_2708271_3 ABC transporter transmembrane region K06147,K18893 - - 0.000000000000000002009 88.0
DTH2_k127_2708271_4 ABC transporter K06147,K18893 - - 0.0000000000000007507 81.0
DTH2_k127_2713909_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 304.0
DTH2_k127_2713909_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 258.0
DTH2_k127_2890705_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.232e-312 965.0
DTH2_k127_2890705_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 4.696e-236 734.0
DTH2_k127_2890705_10 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000037 187.0
DTH2_k127_2890705_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002049 83.0
DTH2_k127_2890705_12 - - - - 0.0002922 49.0
DTH2_k127_2890705_2 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 461.0
DTH2_k127_2890705_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 437.0
DTH2_k127_2890705_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 430.0
DTH2_k127_2890705_5 UTRA domain K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 349.0
DTH2_k127_2890705_6 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 321.0
DTH2_k127_2890705_7 Bacterial regulatory proteins, lacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 283.0
DTH2_k127_2890705_8 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
DTH2_k127_2890705_9 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000000000000003313 175.0
DTH2_k127_2891303_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1639.0
DTH2_k127_2891303_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 6.645e-264 824.0
DTH2_k127_2891303_10 Histidine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000003576 221.0
DTH2_k127_2891303_11 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000001383 177.0
DTH2_k127_2891303_12 - - - - 0.000000000000000000000000000000000000000009893 159.0
DTH2_k127_2891303_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000003695 119.0
DTH2_k127_2891303_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 502.0
DTH2_k127_2891303_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 495.0
DTH2_k127_2891303_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 446.0
DTH2_k127_2891303_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 443.0
DTH2_k127_2891303_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 392.0
DTH2_k127_2891303_7 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 339.0
DTH2_k127_2891303_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 306.0
DTH2_k127_2891303_9 Domain of unknown function (DUF309) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003106 231.0
DTH2_k127_2903124_0 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 0.0 1508.0
DTH2_k127_2903124_1 Highly conserved protein containing a thioredoxin domain K06888 - - 1.274e-243 771.0
DTH2_k127_2903124_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
DTH2_k127_2903124_11 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000007083 187.0
DTH2_k127_2903124_12 Formate dehydrogenase gamma subunit K00127 - - 0.00000000000000000000000000000000000000000000005997 179.0
DTH2_k127_2903124_13 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000001313 137.0
DTH2_k127_2903124_14 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000000000000008444 102.0
DTH2_k127_2903124_15 - - - - 0.00000000000000000001133 95.0
DTH2_k127_2903124_16 - - - - 0.000000000000000007315 93.0
DTH2_k127_2903124_17 - - - - 0.00002189 53.0
DTH2_k127_2903124_2 NADH-quinone oxidoreductase subunit F K00124 - - 1.177e-223 704.0
DTH2_k127_2903124_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 507.0
DTH2_k127_2903124_4 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
DTH2_k127_2903124_5 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 439.0
DTH2_k127_2903124_6 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 422.0
DTH2_k127_2903124_7 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
DTH2_k127_2903124_8 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
DTH2_k127_2903124_9 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 263.0
DTH2_k127_2974317_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.32e-251 783.0
DTH2_k127_2974317_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.104e-227 708.0
DTH2_k127_2974317_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 571.0
DTH2_k127_2974317_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 488.0
DTH2_k127_2974317_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
DTH2_k127_2974317_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
DTH2_k127_2974317_6 LysM domain K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 320.0
DTH2_k127_2974317_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000005875 215.0
DTH2_k127_2974317_8 Sporulation related domain K03749 - - 0.0000000000000000000000124 110.0
DTH2_k127_2974317_9 Colicin V production protein K03558 - - 0.000000000000000000002029 102.0
DTH2_k127_2976712_0 COG3666 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 591.0
DTH2_k127_3032920_0 TonB-dependent receptor K02014 - - 0.0 1071.0
DTH2_k127_3032920_1 Transposase K07497 - - 0.00000000008004 63.0
DTH2_k127_3032920_2 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000005867 56.0
DTH2_k127_3041739_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 498.0
DTH2_k127_3041739_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 334.0
DTH2_k127_3041739_2 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001556 239.0
DTH2_k127_3041739_3 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000001241 186.0
DTH2_k127_3049889_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1229.0
DTH2_k127_3049889_1 type VI secretion protein K11900 - - 1.286e-284 878.0
DTH2_k127_3049889_10 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000002233 190.0
DTH2_k127_3049889_11 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.00000000000000000000000000000000000000000000000001266 187.0
DTH2_k127_3049889_12 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000144 144.0
DTH2_k127_3049889_13 - - - - 0.00000000000257 79.0
DTH2_k127_3049889_14 - - - - 0.0000004035 52.0
DTH2_k127_3049889_2 Type VI secretion protein K11896 - - 3.823e-255 802.0
DTH2_k127_3049889_3 rhs element vgr protein K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 466.0
DTH2_k127_3049889_4 Signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 409.0
DTH2_k127_3049889_5 type VI secretion protein K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 321.0
DTH2_k127_3049889_6 Virulence protein SciE type K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 314.0
DTH2_k127_3049889_7 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 292.0
DTH2_k127_3049889_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 278.0
DTH2_k127_3049889_9 PFAM ImpA domain protein K11902 - - 0.00000000000000000000000000000000000000000000000000000000000000002318 236.0
DTH2_k127_3081055_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1124.0
DTH2_k127_3081055_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1014.0
DTH2_k127_3081055_10 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 422.0
DTH2_k127_3081055_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 398.0
DTH2_k127_3081055_12 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 387.0
DTH2_k127_3081055_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 368.0
DTH2_k127_3081055_14 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 335.0
DTH2_k127_3081055_15 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 318.0
DTH2_k127_3081055_16 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 283.0
DTH2_k127_3081055_17 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 273.0
DTH2_k127_3081055_18 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000002807 234.0
DTH2_k127_3081055_19 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000003568 196.0
DTH2_k127_3081055_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.916e-288 899.0
DTH2_k127_3081055_20 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000002723 162.0
DTH2_k127_3081055_21 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000006263 141.0
DTH2_k127_3081055_22 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000002147 131.0
DTH2_k127_3081055_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.486e-286 899.0
DTH2_k127_3081055_4 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 526.0
DTH2_k127_3081055_5 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 466.0
DTH2_k127_3081055_6 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 449.0
DTH2_k127_3081055_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 437.0
DTH2_k127_3081055_8 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 443.0
DTH2_k127_3081055_9 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 411.0
DTH2_k127_3184392_0 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 529.0
DTH2_k127_3184392_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
DTH2_k127_3184392_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 295.0
DTH2_k127_3184392_3 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000003537 122.0
DTH2_k127_3296825_0 DNA polymerase X family K02347 - - 6.277e-234 736.0
DTH2_k127_3296825_1 Sodium/calcium exchanger protein K07301 - - 2.557e-206 644.0
DTH2_k127_3296825_10 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
DTH2_k127_3296825_11 Exopolysaccharide synthesis, ExoD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 300.0
DTH2_k127_3296825_12 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 287.0
DTH2_k127_3296825_13 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 241.0
DTH2_k127_3296825_14 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000000000000002455 223.0
DTH2_k127_3296825_15 - - - - 0.000000000000000000000000000000000000000000000000000000000001686 212.0
DTH2_k127_3296825_16 - - - - 0.00000000000000000000000000000000000000000000000000000000005895 207.0
DTH2_k127_3296825_17 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
DTH2_k127_3296825_18 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000001963 160.0
DTH2_k127_3296825_19 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000003584 145.0
DTH2_k127_3296825_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 641.0
DTH2_k127_3296825_20 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002921 138.0
DTH2_k127_3296825_21 response regulator - - - 0.000000000000000000000000008568 124.0
DTH2_k127_3296825_22 - - - - 0.00000000000000001153 88.0
DTH2_k127_3296825_23 - - - - 0.000000000155 67.0
DTH2_k127_3296825_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 612.0
DTH2_k127_3296825_4 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 514.0
DTH2_k127_3296825_5 cystathionine K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 447.0
DTH2_k127_3296825_6 Haemolysin-type calcium-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 467.0
DTH2_k127_3296825_7 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 447.0
DTH2_k127_3296825_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 426.0
DTH2_k127_3296825_9 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
DTH2_k127_3331935_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
DTH2_k127_3331935_1 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000001501 230.0
DTH2_k127_3331935_2 oxidoreductase K04090 - 1.2.7.8 0.0000000000000000000000000000000000000000004608 159.0
DTH2_k127_3331935_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000266 84.0
DTH2_k127_3459608_0 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1251.0
DTH2_k127_3459608_1 MMPL family K07003 - - 0.0 1064.0
DTH2_k127_3459608_10 Quinohemoprotein amine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 399.0
DTH2_k127_3459608_11 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 411.0
DTH2_k127_3459608_12 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 331.0
DTH2_k127_3459608_13 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
DTH2_k127_3459608_14 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006797 259.0
DTH2_k127_3459608_15 Methylamine dehydrogenase accessory protein MauD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007872 250.0
DTH2_k127_3459608_16 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003639 243.0
DTH2_k127_3459608_17 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006025 240.0
DTH2_k127_3459608_18 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002015 243.0
DTH2_k127_3459608_19 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000000000000000004406 193.0
DTH2_k127_3459608_2 AMP-binding enzyme K00666 - - 8.356e-298 924.0
DTH2_k127_3459608_20 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000001762 145.0
DTH2_k127_3459608_21 Cytochrome c - - - 0.0000000000000000000000000001753 121.0
DTH2_k127_3459608_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000123 94.0
DTH2_k127_3459608_23 Cytochrome B561 K12262 - - 0.00000886 48.0
DTH2_k127_3459608_3 Protein of unknown function (DUF1302) - - - 6.765e-233 735.0
DTH2_k127_3459608_4 Protein of unknown function (DUF1329) - - - 4.319e-222 696.0
DTH2_k127_3459608_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 1.483e-205 653.0
DTH2_k127_3459608_6 Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - 4.034e-195 621.0
DTH2_k127_3459608_7 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 608.0
DTH2_k127_3459608_8 Radical SAM superfamily K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 522.0
DTH2_k127_3459608_9 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 407.0
DTH2_k127_3516670_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.065e-290 897.0
DTH2_k127_3516670_1 ABC transporter transmembrane region - - - 9.928e-243 763.0
DTH2_k127_3516670_10 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 516.0
DTH2_k127_3516670_11 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 516.0
DTH2_k127_3516670_12 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 512.0
DTH2_k127_3516670_13 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 475.0
DTH2_k127_3516670_14 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 451.0
DTH2_k127_3516670_15 COG3980 Spore coat polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 438.0
DTH2_k127_3516670_16 TIGRFAM rfaE bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 411.0
DTH2_k127_3516670_17 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 359.0
DTH2_k127_3516670_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 331.0
DTH2_k127_3516670_19 Histidine kinase K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 340.0
DTH2_k127_3516670_2 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 1.804e-206 650.0
DTH2_k127_3516670_20 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 328.0
DTH2_k127_3516670_21 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 330.0
DTH2_k127_3516670_22 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 325.0
DTH2_k127_3516670_23 Glycosyl transferase 4-like domain K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 317.0
DTH2_k127_3516670_24 Cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 304.0
DTH2_k127_3516670_25 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 293.0
DTH2_k127_3516670_26 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000187 282.0
DTH2_k127_3516670_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000296 274.0
DTH2_k127_3516670_29 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 258.0
DTH2_k127_3516670_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 5.553e-204 644.0
DTH2_k127_3516670_30 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000483 244.0
DTH2_k127_3516670_31 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000001636 230.0
DTH2_k127_3516670_32 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000007425 228.0
DTH2_k127_3516670_33 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000004054 215.0
DTH2_k127_3516670_34 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000003772 209.0
DTH2_k127_3516670_35 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000001036 213.0
DTH2_k127_3516670_36 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000004508 205.0
DTH2_k127_3516670_37 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000001109 203.0
DTH2_k127_3516670_38 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000008177 203.0
DTH2_k127_3516670_39 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000003012 186.0
DTH2_k127_3516670_4 Putative zinc binding domain - - - 7.346e-203 640.0
DTH2_k127_3516670_40 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000002192 173.0
DTH2_k127_3516670_41 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000001306 176.0
DTH2_k127_3516670_42 Glycosyltransferase like family 2 K13005 - 2.4.1.60 0.0000000000000000000000000000000000000001132 164.0
DTH2_k127_3516670_43 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000009164 147.0
DTH2_k127_3516670_44 transcriptional regulator - - - 0.00000000000000000000000000000000836 130.0
DTH2_k127_3516670_45 CheW-like domain K02659 - - 0.0000000000000000000000000000001045 130.0
DTH2_k127_3516670_46 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000442 119.0
DTH2_k127_3516670_47 PIN domain - - - 0.00000000000000000000000000116 116.0
DTH2_k127_3516670_48 SpoVT / AbrB like domain - - - 0.00000000000332 70.0
DTH2_k127_3516670_49 CRISPR_assoc - - - 0.00001269 55.0
DTH2_k127_3516670_5 tRNA processing - - - 8.492e-202 633.0
DTH2_k127_3516670_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 576.0
DTH2_k127_3516670_7 Multidrug MFS transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 529.0
DTH2_k127_3516670_8 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 543.0
DTH2_k127_3516670_9 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 522.0
DTH2_k127_3625254_0 MCM2/3/5 family K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 452.0
DTH2_k127_3625254_1 Prokaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000001384 167.0
DTH2_k127_3625254_2 cytochrome P450 - - - 0.0000000000000001841 86.0
DTH2_k127_3643196_0 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 439.0
DTH2_k127_3643196_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 298.0
DTH2_k127_3690584_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1430.0
DTH2_k127_3690584_1 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1188.0
DTH2_k127_3690584_10 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.806e-211 665.0
DTH2_k127_3690584_100 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000273 181.0
DTH2_k127_3690584_101 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000007444 175.0
DTH2_k127_3690584_102 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000002174 178.0
DTH2_k127_3690584_103 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000006812 165.0
DTH2_k127_3690584_104 Type II secretory pathway, component - - - 0.00000000000000000000000000000000000000000108 167.0
DTH2_k127_3690584_105 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000002312 168.0
DTH2_k127_3690584_106 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000009081 152.0
DTH2_k127_3690584_107 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000001466 151.0
DTH2_k127_3690584_108 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000001404 140.0
DTH2_k127_3690584_109 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000001689 145.0
DTH2_k127_3690584_11 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 608.0
DTH2_k127_3690584_110 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000004231 145.0
DTH2_k127_3690584_111 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000002025 136.0
DTH2_k127_3690584_112 sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000006646 133.0
DTH2_k127_3690584_113 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000007155 134.0
DTH2_k127_3690584_114 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000000000000000000000000000001422 137.0
DTH2_k127_3690584_115 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000008091 131.0
DTH2_k127_3690584_116 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000001765 116.0
DTH2_k127_3690584_117 Putative transposase - - - 0.0000000000000000000000001805 123.0
DTH2_k127_3690584_118 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000006241 109.0
DTH2_k127_3690584_119 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000000000000000004705 104.0
DTH2_k127_3690584_12 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 597.0
DTH2_k127_3690584_120 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000001018 97.0
DTH2_k127_3690584_121 Protein of unknown function (DUF2970) - - - 0.000000000000000001085 91.0
DTH2_k127_3690584_122 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000001577 94.0
DTH2_k127_3690584_123 PFAM PsiF repeat protein - - - 0.00000000006757 65.0
DTH2_k127_3690584_124 mercury ion transmembrane transporter activity - - - 0.0000000008497 64.0
DTH2_k127_3690584_125 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000001564 61.0
DTH2_k127_3690584_127 PFAM GCN5-related N-acetyltransferase - - - 0.00000343 59.0
DTH2_k127_3690584_128 Tetratricopeptide repeat - - - 0.000005176 59.0
DTH2_k127_3690584_129 - - - - 0.0009263 49.0
DTH2_k127_3690584_13 permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 609.0
DTH2_k127_3690584_14 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 605.0
DTH2_k127_3690584_15 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 593.0
DTH2_k127_3690584_16 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 589.0
DTH2_k127_3690584_17 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 581.0
DTH2_k127_3690584_18 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 559.0
DTH2_k127_3690584_19 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 562.0
DTH2_k127_3690584_2 Elongation factor G, domain IV K02355 - - 2.286e-307 955.0
DTH2_k127_3690584_20 SpoVR family K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 556.0
DTH2_k127_3690584_21 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 547.0
DTH2_k127_3690584_22 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 545.0
DTH2_k127_3690584_23 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 523.0
DTH2_k127_3690584_24 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 520.0
DTH2_k127_3690584_25 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 518.0
DTH2_k127_3690584_26 Cobalamin biosynthesis protein CobW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 510.0
DTH2_k127_3690584_27 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 503.0
DTH2_k127_3690584_28 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 507.0
DTH2_k127_3690584_29 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 477.0
DTH2_k127_3690584_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.302e-304 938.0
DTH2_k127_3690584_30 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 470.0
DTH2_k127_3690584_31 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 466.0
DTH2_k127_3690584_32 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 463.0
DTH2_k127_3690584_33 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 450.0
DTH2_k127_3690584_34 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 425.0
DTH2_k127_3690584_35 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 425.0
DTH2_k127_3690584_36 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 422.0
DTH2_k127_3690584_37 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 420.0
DTH2_k127_3690584_38 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 424.0
DTH2_k127_3690584_39 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 412.0
DTH2_k127_3690584_4 PrkA AAA domain K07180 - - 8.929e-275 859.0
DTH2_k127_3690584_40 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 420.0
DTH2_k127_3690584_41 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 404.0
DTH2_k127_3690584_42 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 407.0
DTH2_k127_3690584_43 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
DTH2_k127_3690584_44 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 388.0
DTH2_k127_3690584_45 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008115 387.0
DTH2_k127_3690584_46 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 383.0
DTH2_k127_3690584_47 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 384.0
DTH2_k127_3690584_48 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 381.0
DTH2_k127_3690584_49 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 402.0
DTH2_k127_3690584_5 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.018e-256 809.0
DTH2_k127_3690584_50 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 379.0
DTH2_k127_3690584_51 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 371.0
DTH2_k127_3690584_52 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
DTH2_k127_3690584_53 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 343.0
DTH2_k127_3690584_54 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 340.0
DTH2_k127_3690584_55 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 332.0
DTH2_k127_3690584_56 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 331.0
DTH2_k127_3690584_57 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 327.0
DTH2_k127_3690584_58 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 321.0
DTH2_k127_3690584_59 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 313.0
DTH2_k127_3690584_6 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.167e-244 773.0
DTH2_k127_3690584_60 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 313.0
DTH2_k127_3690584_61 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 306.0
DTH2_k127_3690584_62 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 299.0
DTH2_k127_3690584_63 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 294.0
DTH2_k127_3690584_64 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 284.0
DTH2_k127_3690584_65 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002213 285.0
DTH2_k127_3690584_66 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000049 284.0
DTH2_k127_3690584_67 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007469 278.0
DTH2_k127_3690584_68 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
DTH2_k127_3690584_69 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001628 269.0
DTH2_k127_3690584_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.681e-229 714.0
DTH2_k127_3690584_70 ABC transporter permease K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002875 270.0
DTH2_k127_3690584_71 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 265.0
DTH2_k127_3690584_72 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
DTH2_k127_3690584_73 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000004334 265.0
DTH2_k127_3690584_74 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001886 272.0
DTH2_k127_3690584_75 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
DTH2_k127_3690584_76 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000001709 248.0
DTH2_k127_3690584_77 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002068 256.0
DTH2_k127_3690584_78 cytochrome C oxidase K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004004 244.0
DTH2_k127_3690584_79 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
DTH2_k127_3690584_8 Peptidase family S49 K04773 - - 7.421e-216 687.0
DTH2_k127_3690584_80 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002479 244.0
DTH2_k127_3690584_81 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000008164 250.0
DTH2_k127_3690584_82 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000348 235.0
DTH2_k127_3690584_83 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000000000000000002111 241.0
DTH2_k127_3690584_84 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
DTH2_k127_3690584_85 Hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000521 228.0
DTH2_k127_3690584_86 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
DTH2_k127_3690584_87 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000001489 225.0
DTH2_k127_3690584_88 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000423 219.0
DTH2_k127_3690584_89 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000003342 219.0
DTH2_k127_3690584_9 Aldehyde dehydrogenase family - - - 2.626e-212 667.0
DTH2_k127_3690584_90 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000000000000000000000428 224.0
DTH2_k127_3690584_91 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000007825 222.0
DTH2_k127_3690584_92 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
DTH2_k127_3690584_93 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000974 207.0
DTH2_k127_3690584_94 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000007215 204.0
DTH2_k127_3690584_95 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000001276 194.0
DTH2_k127_3690584_96 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000003735 192.0
DTH2_k127_3690584_97 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000000001443 194.0
DTH2_k127_3690584_98 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000001505 186.0
DTH2_k127_3690584_99 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000001568 196.0
DTH2_k127_3749461_0 oxidoreductase activity - - - 0.0 1111.0
DTH2_k127_3749461_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5e-324 998.0
DTH2_k127_3749461_10 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 599.0
DTH2_k127_3749461_11 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 583.0
DTH2_k127_3749461_12 PFAM Mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 572.0
DTH2_k127_3749461_13 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 556.0
DTH2_k127_3749461_14 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 556.0
DTH2_k127_3749461_15 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 556.0
DTH2_k127_3749461_16 Belongs to the ABC transporter superfamily K02032,K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 554.0
DTH2_k127_3749461_17 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 542.0
DTH2_k127_3749461_18 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 527.0
DTH2_k127_3749461_19 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 521.0
DTH2_k127_3749461_2 extracellular solute-binding protein, family 5 K02035 - - 3.168e-307 946.0
DTH2_k127_3749461_20 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 522.0
DTH2_k127_3749461_21 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 447.0
DTH2_k127_3749461_22 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 451.0
DTH2_k127_3749461_23 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 447.0
DTH2_k127_3749461_24 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 441.0
DTH2_k127_3749461_25 LysR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 428.0
DTH2_k127_3749461_26 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 417.0
DTH2_k127_3749461_27 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 403.0
DTH2_k127_3749461_28 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 396.0
DTH2_k127_3749461_29 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 392.0
DTH2_k127_3749461_3 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 6.018e-289 895.0
DTH2_k127_3749461_30 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 385.0
DTH2_k127_3749461_31 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 380.0
DTH2_k127_3749461_32 BFD domain protein 2Fe-2S -binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 374.0
DTH2_k127_3749461_33 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 355.0
DTH2_k127_3749461_34 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
DTH2_k127_3749461_35 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 350.0
DTH2_k127_3749461_36 Superoxide dismutase K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
DTH2_k127_3749461_37 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 341.0
DTH2_k127_3749461_38 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 334.0
DTH2_k127_3749461_39 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
DTH2_k127_3749461_4 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.984e-288 910.0
DTH2_k127_3749461_40 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 323.0
DTH2_k127_3749461_41 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 309.0
DTH2_k127_3749461_42 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 315.0
DTH2_k127_3749461_43 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002666 288.0
DTH2_k127_3749461_44 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002273 278.0
DTH2_k127_3749461_45 Chromate resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007529 279.0
DTH2_k127_3749461_46 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000048 268.0
DTH2_k127_3749461_47 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007581 275.0
DTH2_k127_3749461_48 negative regulator of sigma E activity K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000963 272.0
DTH2_k127_3749461_49 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009977 258.0
DTH2_k127_3749461_5 Belongs to the malate synthase family K01638 - 2.3.3.9 3.933e-282 873.0
DTH2_k127_3749461_50 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009975 249.0
DTH2_k127_3749461_51 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000001377 254.0
DTH2_k127_3749461_52 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000004177 236.0
DTH2_k127_3749461_53 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000000004564 232.0
DTH2_k127_3749461_54 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
DTH2_k127_3749461_55 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
DTH2_k127_3749461_56 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000116 206.0
DTH2_k127_3749461_57 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000005392 198.0
DTH2_k127_3749461_58 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000003349 192.0
DTH2_k127_3749461_59 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000005226 184.0
DTH2_k127_3749461_6 Isocitrate lyase K01637 - 4.1.3.1 1.52e-250 777.0
DTH2_k127_3749461_60 oxidation protein K17227 - - 0.000000000000000000000000000000000000000002544 157.0
DTH2_k127_3749461_61 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000002909 160.0
DTH2_k127_3749461_62 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000009052 160.0
DTH2_k127_3749461_63 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000001299 156.0
DTH2_k127_3749461_64 Thioredoxin-like - - - 0.000000000000000000000000000000000000005731 151.0
DTH2_k127_3749461_65 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000003012 132.0
DTH2_k127_3749461_66 Peptidase S24-like - - - 0.000000000000000000000000000000002189 133.0
DTH2_k127_3749461_67 Phage integrase family - - - 0.00000000000000000000000000000004102 133.0
DTH2_k127_3749461_68 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000005578 129.0
DTH2_k127_3749461_69 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000005035 112.0
DTH2_k127_3749461_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.884e-247 776.0
DTH2_k127_3749461_70 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000001199 111.0
DTH2_k127_3749461_71 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000002997 105.0
DTH2_k127_3749461_72 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000109 104.0
DTH2_k127_3749461_73 Domain of unknown function (DUF4845) - - - 0.00000000000000000000429 97.0
DTH2_k127_3749461_74 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000001078 89.0
DTH2_k127_3749461_76 - - - - 0.000000000928 64.0
DTH2_k127_3749461_77 DsrE/DsrF-like family K09004 - - 0.0000000009761 65.0
DTH2_k127_3749461_78 Anti sigma-E protein RseA K03597 - - 0.000000001019 67.0
DTH2_k127_3749461_79 - - - - 0.000006097 50.0
DTH2_k127_3749461_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.814e-210 660.0
DTH2_k127_3749461_80 Acetyltransferase (GNAT) domain - - - 0.00003278 52.0
DTH2_k127_3749461_81 Acetyltransferase (GNAT) domain - - - 0.0004646 47.0
DTH2_k127_3749461_9 Chromate K07240 - - 1.011e-204 646.0
DTH2_k127_3793346_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1230.0
DTH2_k127_3793346_1 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1052.0
DTH2_k127_3793346_10 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 498.0
DTH2_k127_3793346_11 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 481.0
DTH2_k127_3793346_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 479.0
DTH2_k127_3793346_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 464.0
DTH2_k127_3793346_14 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
DTH2_k127_3793346_15 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 449.0
DTH2_k127_3793346_16 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 445.0
DTH2_k127_3793346_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 462.0
DTH2_k127_3793346_18 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 445.0
DTH2_k127_3793346_19 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 439.0
DTH2_k127_3793346_2 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 8.805e-313 960.0
DTH2_k127_3793346_20 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
DTH2_k127_3793346_21 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 396.0
DTH2_k127_3793346_22 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 413.0
DTH2_k127_3793346_23 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
DTH2_k127_3793346_24 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 374.0
DTH2_k127_3793346_25 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 357.0
DTH2_k127_3793346_26 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
DTH2_k127_3793346_27 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 334.0
DTH2_k127_3793346_28 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
DTH2_k127_3793346_29 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
DTH2_k127_3793346_3 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 2.216e-312 969.0
DTH2_k127_3793346_30 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001095 275.0
DTH2_k127_3793346_31 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005869 279.0
DTH2_k127_3793346_32 Biopolymer transport K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
DTH2_k127_3793346_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001573 280.0
DTH2_k127_3793346_34 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001355 256.0
DTH2_k127_3793346_35 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
DTH2_k127_3793346_36 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005888 262.0
DTH2_k127_3793346_37 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003709 231.0
DTH2_k127_3793346_38 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000009101 229.0
DTH2_k127_3793346_39 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000006811 199.0
DTH2_k127_3793346_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.465e-296 917.0
DTH2_k127_3793346_40 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000004608 196.0
DTH2_k127_3793346_41 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000001148 194.0
DTH2_k127_3793346_42 Transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000005416 184.0
DTH2_k127_3793346_43 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002422 168.0
DTH2_k127_3793346_44 Biopolymer transport protein, ExbD K03559 - - 0.00000000000000000000000000000000000000003469 156.0
DTH2_k127_3793346_45 Cytochrome K08738 - - 0.0000000000000000000000000000000001356 134.0
DTH2_k127_3793346_46 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000003937 138.0
DTH2_k127_3793346_47 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000001347 128.0
DTH2_k127_3793346_48 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000007239 124.0
DTH2_k127_3793346_49 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000001629 119.0
DTH2_k127_3793346_5 AMP-binding enzyme C-terminal domain - - - 2.602e-229 720.0
DTH2_k127_3793346_50 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000007657 118.0
DTH2_k127_3793346_51 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000001234 109.0
DTH2_k127_3793346_52 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000003478 97.0
DTH2_k127_3793346_53 - - - - 0.0000000000001476 73.0
DTH2_k127_3793346_54 - - - - 0.000611 46.0
DTH2_k127_3793346_6 AMP-binding enzyme C-terminal domain K18661 - - 1.153e-217 687.0
DTH2_k127_3793346_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 604.0
DTH2_k127_3793346_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 582.0
DTH2_k127_3793346_9 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 515.0
DTH2_k127_3800468_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1052.0
DTH2_k127_3800468_1 Fe-S oxidoreductase K21834 - - 5.129e-276 868.0
DTH2_k127_3800468_10 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 426.0
DTH2_k127_3800468_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 396.0
DTH2_k127_3800468_12 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 407.0
DTH2_k127_3800468_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
DTH2_k127_3800468_14 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 355.0
DTH2_k127_3800468_15 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 348.0
DTH2_k127_3800468_16 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 324.0
DTH2_k127_3800468_17 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 290.0
DTH2_k127_3800468_18 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 269.0
DTH2_k127_3800468_19 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
DTH2_k127_3800468_2 Branched-chain amino acid transport system / permease component K01995,K01998 - - 4.469e-258 808.0
DTH2_k127_3800468_20 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
DTH2_k127_3800468_21 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000002455 198.0
DTH2_k127_3800468_22 DsrE/DsrF-like family K07235 - - 0.000000000000000000000000000000000000000000000000000001771 193.0
DTH2_k127_3800468_23 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000000000000000000000000000001798 194.0
DTH2_k127_3800468_24 Belongs to the DsrF TusC family K07236 - - 0.0000000000000000000000000000000000000000000000001575 178.0
DTH2_k127_3800468_25 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000005639 173.0
DTH2_k127_3800468_26 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000002065 155.0
DTH2_k127_3800468_27 Cas6 Crispr - - - 0.000000000000000000000000000000000000001592 158.0
DTH2_k127_3800468_28 - - - - 0.000000000000000000000000000000000000001666 157.0
DTH2_k127_3800468_29 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000001925 151.0
DTH2_k127_3800468_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.322e-247 767.0
DTH2_k127_3800468_30 - - - - 0.00000000000000000000000000002426 125.0
DTH2_k127_3800468_31 DsrH like protein K07237 - - 0.0000000000000000000000000001967 121.0
DTH2_k127_3800468_32 - - - - 0.0000000000000000000007405 98.0
DTH2_k127_3800468_33 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000005051 90.0
DTH2_k127_3800468_4 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 7.6e-232 727.0
DTH2_k127_3800468_5 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 5.982e-223 698.0
DTH2_k127_3800468_6 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 5.591e-213 664.0
DTH2_k127_3800468_7 Periplasmic binding protein K01999 - - 5.347e-203 648.0
DTH2_k127_3800468_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 447.0
DTH2_k127_3800468_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 428.0
DTH2_k127_3867021_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.966e-293 904.0
DTH2_k127_3867021_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 2.75e-207 646.0
DTH2_k127_3867021_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 430.0
DTH2_k127_3867021_3 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 401.0
DTH2_k127_3867021_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 376.0
DTH2_k127_3867021_5 acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 361.0
DTH2_k127_3867021_6 synthase small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 292.0
DTH2_k127_3870491_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 9.732e-308 962.0
DTH2_k127_3870491_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 3.351e-214 685.0
DTH2_k127_3870491_10 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000001072 239.0
DTH2_k127_3870491_11 PFAM HupH hydrogenase expression protein K03618 - - 0.0000000000000000000000000000000000000000000000000000000000000000002079 239.0
DTH2_k127_3870491_12 Hydrogenase maturation protease K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000006812 211.0
DTH2_k127_3870491_13 Ni,Fe-hydrogenase I large subunit - - - 0.000000000000000000000000000000000000000000000000000001414 206.0
DTH2_k127_3870491_14 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000006183 152.0
DTH2_k127_3870491_15 transcriptional regulators K03892 - - 0.000000000000000000000000000000000001719 141.0
DTH2_k127_3870491_16 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.000000000000000000000000000000000004699 143.0
DTH2_k127_3870491_17 Rubredoxin - - - 0.000000000000000000000000000001235 123.0
DTH2_k127_3870491_18 Hydrogenase-1 expression protein HyaE K03619 - - 0.000000000000000000000000002299 118.0
DTH2_k127_3870491_19 Hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000005325 111.0
DTH2_k127_3870491_2 Formyl transferase K19640 - - 4.845e-212 676.0
DTH2_k127_3870491_20 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000001077 109.0
DTH2_k127_3870491_21 Helix-turn-helix K21498 - - 0.00000000000000000000006239 99.0
DTH2_k127_3870491_22 - - - - 0.0000000000000000000001563 104.0
DTH2_k127_3870491_23 NHL repeat - - - 0.000000000000009587 85.0
DTH2_k127_3870491_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000001148 81.0
DTH2_k127_3870491_25 PFAM UvrB UvrC protein - - - 0.000001354 59.0
DTH2_k127_3870491_3 Belongs to the HypD family K04654 - - 7.108e-202 634.0
DTH2_k127_3870491_4 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 533.0
DTH2_k127_3870491_5 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 519.0
DTH2_k127_3870491_7 Hydrogenase K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 423.0
DTH2_k127_3870491_8 6-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 426.0
DTH2_k127_3870491_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002062 249.0
DTH2_k127_393292_0 Belongs to the 'phage' integrase family - - - 7.668e-220 687.0
DTH2_k127_393292_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 558.0
DTH2_k127_393292_2 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 428.0
DTH2_k127_3969510_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1238.0
DTH2_k127_3969510_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1024.0
DTH2_k127_3969510_10 D-amino acid K00285 - 1.4.5.1 1.146e-209 657.0
DTH2_k127_3969510_100 Histidine kinase-like ATPase domain - - - 0.000000000005629 73.0
DTH2_k127_3969510_101 - - - - 0.000000002124 62.0
DTH2_k127_3969510_102 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000351 61.0
DTH2_k127_3969510_11 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.672e-208 662.0
DTH2_k127_3969510_12 L-carnitine dehydratase bile acid-inducible protein F - - - 2.017e-202 636.0
DTH2_k127_3969510_13 Histidine ammonia-lyase K01745 - 4.3.1.3 8.074e-199 631.0
DTH2_k127_3969510_14 Phosphoesterase family - - - 2.067e-197 627.0
DTH2_k127_3969510_15 Histidine ammonia-lyase K01745 - 4.3.1.3 2.776e-195 626.0
DTH2_k127_3969510_16 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 606.0
DTH2_k127_3969510_17 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 573.0
DTH2_k127_3969510_18 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 572.0
DTH2_k127_3969510_19 Pyridoxamine 5'-phosphate K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 574.0
DTH2_k127_3969510_2 Belongs to the malic enzymes family K00029 - 1.1.1.40 4.79e-320 996.0
DTH2_k127_3969510_20 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 541.0
DTH2_k127_3969510_21 PFAM extracellular solute-binding protein family 1 K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
DTH2_k127_3969510_22 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 512.0
DTH2_k127_3969510_23 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 512.0
DTH2_k127_3969510_24 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 502.0
DTH2_k127_3969510_25 aldo keto reductase K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 497.0
DTH2_k127_3969510_26 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 481.0
DTH2_k127_3969510_27 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 474.0
DTH2_k127_3969510_28 Multidrug ABC transporter permease K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 471.0
DTH2_k127_3969510_29 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 469.0
DTH2_k127_3969510_3 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 8.319e-318 982.0
DTH2_k127_3969510_30 Serine hydroxymethyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 476.0
DTH2_k127_3969510_31 glycine betaine K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 460.0
DTH2_k127_3969510_32 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 481.0
DTH2_k127_3969510_33 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 450.0
DTH2_k127_3969510_34 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
DTH2_k127_3969510_35 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 433.0
DTH2_k127_3969510_36 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 433.0
DTH2_k127_3969510_37 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 431.0
DTH2_k127_3969510_38 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 423.0
DTH2_k127_3969510_39 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 434.0
DTH2_k127_3969510_4 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.718e-303 937.0
DTH2_k127_3969510_40 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 418.0
DTH2_k127_3969510_41 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 412.0
DTH2_k127_3969510_42 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 403.0
DTH2_k127_3969510_43 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 394.0
DTH2_k127_3969510_44 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072,K11076 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 399.0
DTH2_k127_3969510_45 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 386.0
DTH2_k127_3969510_46 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 398.0
DTH2_k127_3969510_47 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 387.0
DTH2_k127_3969510_48 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 384.0
DTH2_k127_3969510_49 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 367.0
DTH2_k127_3969510_5 transport system, fused permease components - - - 3.557e-284 891.0
DTH2_k127_3969510_50 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
DTH2_k127_3969510_51 binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 362.0
DTH2_k127_3969510_52 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 351.0
DTH2_k127_3969510_53 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 346.0
DTH2_k127_3969510_54 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 344.0
DTH2_k127_3969510_55 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 344.0
DTH2_k127_3969510_56 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 345.0
DTH2_k127_3969510_57 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 335.0
DTH2_k127_3969510_58 PFAM conserved K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 340.0
DTH2_k127_3969510_59 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 330.0
DTH2_k127_3969510_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.452e-282 873.0
DTH2_k127_3969510_60 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 334.0
DTH2_k127_3969510_61 COG0451 Nucleoside-diphosphate-sugar epimerases K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
DTH2_k127_3969510_62 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 316.0
DTH2_k127_3969510_63 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 317.0
DTH2_k127_3969510_64 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 304.0
DTH2_k127_3969510_65 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
DTH2_k127_3969510_66 ABC-type proline glycine betaine transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
DTH2_k127_3969510_67 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001894 259.0
DTH2_k127_3969510_68 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000709 264.0
DTH2_k127_3969510_69 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007921 250.0
DTH2_k127_3969510_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.962e-267 827.0
DTH2_k127_3969510_70 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000001668 260.0
DTH2_k127_3969510_71 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000008675 237.0
DTH2_k127_3969510_72 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
DTH2_k127_3969510_73 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003014 232.0
DTH2_k127_3969510_75 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000004517 222.0
DTH2_k127_3969510_76 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
DTH2_k127_3969510_77 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000001496 206.0
DTH2_k127_3969510_78 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000001628 206.0
DTH2_k127_3969510_79 PFAM BLUF domain protein - - - 0.000000000000000000000000000000000000000000000000000000003957 210.0
DTH2_k127_3969510_8 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 6.658e-229 731.0
DTH2_k127_3969510_80 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000459 199.0
DTH2_k127_3969510_81 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000003058 192.0
DTH2_k127_3969510_82 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000802 185.0
DTH2_k127_3969510_83 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000002662 182.0
DTH2_k127_3969510_84 Auxin binding protein - - - 0.00000000000000000000000000000000000000000008211 164.0
DTH2_k127_3969510_85 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000178 163.0
DTH2_k127_3969510_86 OmpA family - - - 0.000000000000000000000000000000000000002431 157.0
DTH2_k127_3969510_87 MaoC like domain - - - 0.000000000000000000000000000000000000004269 151.0
DTH2_k127_3969510_88 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000003927 142.0
DTH2_k127_3969510_89 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000003659 138.0
DTH2_k127_3969510_9 Tripartite tricarboxylate transporter TctA family K07793 - - 1.023e-213 678.0
DTH2_k127_3969510_90 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000002367 117.0
DTH2_k127_3969510_91 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001144 111.0
DTH2_k127_3969510_92 PFAM Thioredoxin K00384 - 1.8.1.9 0.00000000000000000000000001678 114.0
DTH2_k127_3969510_93 PFAM FecR protein - - - 0.000000000000000000000001483 108.0
DTH2_k127_3969510_94 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000002325 100.0
DTH2_k127_3969510_95 Domain of unknown function (DUF1850) - - - 0.000000000000000003878 89.0
DTH2_k127_3969510_96 ATP synthase I chain K02116 - - 0.00000000000000000408 88.0
DTH2_k127_3969510_97 STAS domain K06378 - - 0.000000000000001657 81.0
DTH2_k127_3969510_98 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000002548 73.0
DTH2_k127_3969510_99 Putative transposase - - - 0.000000000002084 67.0
DTH2_k127_402506_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 576.0
DTH2_k127_402506_1 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 493.0
DTH2_k127_402506_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001518 261.0
DTH2_k127_402506_11 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005194 240.0
DTH2_k127_402506_12 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000004339 212.0
DTH2_k127_402506_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000003036 188.0
DTH2_k127_402506_14 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000001362 183.0
DTH2_k127_402506_15 Cytochrome c - - - 0.000000000000000000000000000000001433 143.0
DTH2_k127_402506_16 Cytochrome c - - - 0.0000000000000000000000000002425 128.0
DTH2_k127_402506_17 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000001674 104.0
DTH2_k127_402506_18 lipolytic protein G-D-S-L family - - - 0.00000000000000001082 96.0
DTH2_k127_402506_19 Cytochrome c - - - 0.00000004104 64.0
DTH2_k127_402506_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 411.0
DTH2_k127_402506_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 369.0
DTH2_k127_402506_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 342.0
DTH2_k127_402506_5 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 340.0
DTH2_k127_402506_6 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 322.0
DTH2_k127_402506_7 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 318.0
DTH2_k127_402506_8 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 316.0
DTH2_k127_402506_9 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007108 275.0
DTH2_k127_4042077_0 B12 binding domain K00548 - 2.1.1.13 0.0 1833.0
DTH2_k127_4042077_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1567.0
DTH2_k127_4042077_10 Multicopper oxidase - - - 6.999e-246 777.0
DTH2_k127_4042077_100 Two component transcriptional regulator K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001092 283.0
DTH2_k127_4042077_101 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
DTH2_k127_4042077_102 sequence-specific DNA binding K05804,K13631,K13632,K18325,K19056 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009635,GO:0009636,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032787,GO:0032991,GO:0032993,GO:0035690,GO:0036245,GO:0042180,GO:0042182,GO:0042221,GO:0042493,GO:0042802,GO:0042803,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046185,GO:0046394,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051596,GO:0051716,GO:0060255,GO:0061727,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0072330,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:0140110,GO:1901363,GO:1901562,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001746 286.0
DTH2_k127_4042077_103 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
DTH2_k127_4042077_104 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
DTH2_k127_4042077_105 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003822 271.0
DTH2_k127_4042077_106 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008552 273.0
DTH2_k127_4042077_107 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002316 254.0
DTH2_k127_4042077_108 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000005626 250.0
DTH2_k127_4042077_109 lipoate-protein ligase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
DTH2_k127_4042077_11 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 2.491e-240 751.0
DTH2_k127_4042077_110 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001958 261.0
DTH2_k127_4042077_111 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003601 251.0
DTH2_k127_4042077_112 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000005743 243.0
DTH2_k127_4042077_113 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000006084 259.0
DTH2_k127_4042077_114 Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004252 247.0
DTH2_k127_4042077_115 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
DTH2_k127_4042077_116 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003822 246.0
DTH2_k127_4042077_117 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
DTH2_k127_4042077_118 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
DTH2_k127_4042077_119 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004096 240.0
DTH2_k127_4042077_12 PFAM MmgE PrpD family protein - - - 1.327e-230 721.0
DTH2_k127_4042077_120 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000002149 224.0
DTH2_k127_4042077_121 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000007028 221.0
DTH2_k127_4042077_122 PFAM nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
DTH2_k127_4042077_123 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000000000000000101 211.0
DTH2_k127_4042077_124 - - - - 0.00000000000000000000000000000000000000000000000000000001446 206.0
DTH2_k127_4042077_125 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000003567 205.0
DTH2_k127_4042077_126 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.000000000000000000000000000000000000000000000000000000205 207.0
DTH2_k127_4042077_127 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000001782 192.0
DTH2_k127_4042077_128 Domain of unknown function (DUF4396) - - - 0.000000000000000000000000000000000000000000000000000281 192.0
DTH2_k127_4042077_129 signal peptide protein - - - 0.0000000000000000000000000000000000000000000000000007457 192.0
DTH2_k127_4042077_13 ABC transporter C-terminal domain K15738 - - 3.691e-230 729.0
DTH2_k127_4042077_130 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000006204 183.0
DTH2_k127_4042077_131 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000007442 171.0
DTH2_k127_4042077_132 PIN domain - - - 0.000000000000000000000000000000000000000000001762 171.0
DTH2_k127_4042077_133 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000003291 167.0
DTH2_k127_4042077_134 - - - - 0.00000000000000000000000000000000000000000001012 174.0
DTH2_k127_4042077_135 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000002122 178.0
DTH2_k127_4042077_136 transcriptional - - - 0.0000000000000000000000000000000000000000001548 170.0
DTH2_k127_4042077_137 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000006881 166.0
DTH2_k127_4042077_138 - - - - 0.000000000000000000000000000000000000000003975 164.0
DTH2_k127_4042077_139 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000001576 159.0
DTH2_k127_4042077_14 Prolyl oligopeptidase family - - - 1.285e-229 731.0
DTH2_k127_4042077_140 Lecithin retinol acyltransferase - - - 0.0000000000000000000000000000000000000003116 158.0
DTH2_k127_4042077_141 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000001345 153.0
DTH2_k127_4042077_142 Cyclase dehydrase - - - 0.000000000000000000000000000000000000002239 159.0
DTH2_k127_4042077_143 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000002007 151.0
DTH2_k127_4042077_144 BON domain - - - 0.0000000000000000000000000000000000001372 157.0
DTH2_k127_4042077_145 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000005754 156.0
DTH2_k127_4042077_146 - - - - 0.00000000000000000000000000000000001375 138.0
DTH2_k127_4042077_147 Glycine-zipper domain - - - 0.00000000000000000000000000000000001811 143.0
DTH2_k127_4042077_149 - - - - 0.0000000000000000000000000000000004234 136.0
DTH2_k127_4042077_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.651e-229 716.0
DTH2_k127_4042077_150 Ferredoxin K05337 - - 0.000000000000000000000000000000002147 131.0
DTH2_k127_4042077_151 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.000000000000000000000000000000004639 130.0
DTH2_k127_4042077_152 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000000000157 148.0
DTH2_k127_4042077_153 Domain of unknown function (DUF1857) - - - 0.00000000000000000000000000000002532 131.0
DTH2_k127_4042077_154 toxin-antitoxin pair type II binding K19156 GO:0001558,GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040008,GO:0042802,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000002674 128.0
DTH2_k127_4042077_155 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000001374 126.0
DTH2_k127_4042077_156 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000003703 122.0
DTH2_k127_4042077_157 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000004861 122.0
DTH2_k127_4042077_158 - - - - 0.0000000000000000000000000001449 122.0
DTH2_k127_4042077_159 - - - - 0.0000000000000000000000000007444 119.0
DTH2_k127_4042077_16 cytosine deaminase K01485 - 3.5.4.1 3.06e-228 711.0
DTH2_k127_4042077_160 Cytochrome c K17223 - - 0.0000000000000000000000001325 112.0
DTH2_k127_4042077_161 - - - - 0.00000000000000000000000742 106.0
DTH2_k127_4042077_162 Protein of unknown function (DUF3567) - - - 0.0000000000000000000001598 108.0
DTH2_k127_4042077_163 - - - - 0.000000000000000000000769 100.0
DTH2_k127_4042077_164 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000007732 102.0
DTH2_k127_4042077_165 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000002873 83.0
DTH2_k127_4042077_166 Domain of unknown function (DUF1840) - - - 0.00000000000000041 82.0
DTH2_k127_4042077_167 FAD dependent oxidoreductase K13796 - - 0.0000000000000008464 78.0
DTH2_k127_4042077_168 addiction module killer protein - - - 0.0000000002805 62.0
DTH2_k127_4042077_169 Protein of unknown function (DUF3144) - - - 0.00000002376 67.0
DTH2_k127_4042077_17 TRAP dicarboxylate transporter, DctM subunit K11690 - - 5.391e-222 696.0
DTH2_k127_4042077_171 PFAM CBS domain - - - 0.000008595 55.0
DTH2_k127_4042077_172 response regulator - - - 0.00006446 47.0
DTH2_k127_4042077_173 cobalamin synthesis protein - - - 0.0002922 49.0
DTH2_k127_4042077_18 Ammonium Transporter Family K03320,K06580 - - 1.048e-219 686.0
DTH2_k127_4042077_19 Sulfatase - - - 1.983e-218 691.0
DTH2_k127_4042077_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1283.0
DTH2_k127_4042077_20 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 7.862e-213 685.0
DTH2_k127_4042077_21 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.931e-208 655.0
DTH2_k127_4042077_22 von Willebrand factor, type A K07114 - - 1.849e-204 656.0
DTH2_k127_4042077_23 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 6.251e-197 627.0
DTH2_k127_4042077_24 Transketolase, pyrimidine binding domain K21417 - - 1.393e-194 609.0
DTH2_k127_4042077_25 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 2.295e-194 614.0
DTH2_k127_4042077_26 CitB domain protein K13795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 607.0
DTH2_k127_4042077_27 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 616.0
DTH2_k127_4042077_28 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 607.0
DTH2_k127_4042077_29 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 599.0
DTH2_k127_4042077_3 dna topoisomerase III K03169 - 5.99.1.2 0.0 1143.0
DTH2_k127_4042077_30 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 593.0
DTH2_k127_4042077_31 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 589.0
DTH2_k127_4042077_32 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 584.0
DTH2_k127_4042077_33 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 586.0
DTH2_k127_4042077_34 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 578.0
DTH2_k127_4042077_35 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 564.0
DTH2_k127_4042077_36 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 567.0
DTH2_k127_4042077_37 AMP-binding enzyme K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 565.0
DTH2_k127_4042077_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 559.0
DTH2_k127_4042077_39 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 544.0
DTH2_k127_4042077_4 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1030.0
DTH2_k127_4042077_40 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 533.0
DTH2_k127_4042077_41 basic membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 509.0
DTH2_k127_4042077_42 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 503.0
DTH2_k127_4042077_43 Beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 499.0
DTH2_k127_4042077_44 TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 491.0
DTH2_k127_4042077_45 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 495.0
DTH2_k127_4042077_46 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 497.0
DTH2_k127_4042077_47 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 481.0
DTH2_k127_4042077_48 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 481.0
DTH2_k127_4042077_49 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 484.0
DTH2_k127_4042077_5 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 6.185e-285 889.0
DTH2_k127_4042077_50 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 470.0
DTH2_k127_4042077_51 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 470.0
DTH2_k127_4042077_52 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 463.0
DTH2_k127_4042077_53 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 462.0
DTH2_k127_4042077_54 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 465.0
DTH2_k127_4042077_55 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 455.0
DTH2_k127_4042077_56 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 437.0
DTH2_k127_4042077_57 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 448.0
DTH2_k127_4042077_58 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 433.0
DTH2_k127_4042077_59 PFAM ABC transporter K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 435.0
DTH2_k127_4042077_6 synthetase K01907 - 6.2.1.16 7.252e-285 889.0
DTH2_k127_4042077_60 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 435.0
DTH2_k127_4042077_61 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 431.0
DTH2_k127_4042077_62 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 429.0
DTH2_k127_4042077_63 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 423.0
DTH2_k127_4042077_64 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 419.0
DTH2_k127_4042077_65 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 417.0
DTH2_k127_4042077_66 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 405.0
DTH2_k127_4042077_67 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 407.0
DTH2_k127_4042077_68 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 403.0
DTH2_k127_4042077_69 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 405.0
DTH2_k127_4042077_7 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.086e-279 879.0
DTH2_k127_4042077_70 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 396.0
DTH2_k127_4042077_71 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 402.0
DTH2_k127_4042077_72 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 385.0
DTH2_k127_4042077_73 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 395.0
DTH2_k127_4042077_74 COG1176 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 381.0
DTH2_k127_4042077_75 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 384.0
DTH2_k127_4042077_76 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 374.0
DTH2_k127_4042077_77 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 375.0
DTH2_k127_4042077_78 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 368.0
DTH2_k127_4042077_79 Tripartite ATP-independent periplasmic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 358.0
DTH2_k127_4042077_8 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.645e-259 817.0
DTH2_k127_4042077_80 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
DTH2_k127_4042077_81 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 354.0
DTH2_k127_4042077_82 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
DTH2_k127_4042077_83 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 363.0
DTH2_k127_4042077_84 ABC transporter permease K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 359.0
DTH2_k127_4042077_85 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 354.0
DTH2_k127_4042077_86 coenzyme F420-1:gamma-L-glutamate ligase activity K19285,K19286 - 1.5.1.38,1.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
DTH2_k127_4042077_87 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 341.0
DTH2_k127_4042077_88 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 327.0
DTH2_k127_4042077_89 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
DTH2_k127_4042077_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.968e-256 813.0
DTH2_k127_4042077_90 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
DTH2_k127_4042077_91 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 299.0
DTH2_k127_4042077_92 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 306.0
DTH2_k127_4042077_93 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 302.0
DTH2_k127_4042077_94 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 298.0
DTH2_k127_4042077_95 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 296.0
DTH2_k127_4042077_96 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 291.0
DTH2_k127_4042077_97 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000022 292.0
DTH2_k127_4042077_98 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 294.0
DTH2_k127_4042077_99 DNA import into cell involved in transformation K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 293.0
DTH2_k127_407096_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.081e-301 952.0
DTH2_k127_407096_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 9.047e-234 731.0
DTH2_k127_407096_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000002459 164.0
DTH2_k127_407096_11 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000001333 93.0
DTH2_k127_407096_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 604.0
DTH2_k127_407096_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 477.0
DTH2_k127_407096_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 394.0
DTH2_k127_407096_5 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 381.0
DTH2_k127_407096_6 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008235 263.0
DTH2_k127_407096_7 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003179 239.0
DTH2_k127_407096_8 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000001017 196.0
DTH2_k127_407096_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000005765 186.0
DTH2_k127_4078226_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 5.152e-196 613.0
DTH2_k127_4078226_1 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000006401 215.0
DTH2_k127_4218101_0 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 289.0
DTH2_k127_4218101_1 Phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003497 269.0
DTH2_k127_4218101_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000002734 207.0
DTH2_k127_4265301_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.803e-282 876.0
DTH2_k127_4265301_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 4.759e-258 820.0
DTH2_k127_4265301_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 392.0
DTH2_k127_4265301_11 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 381.0
DTH2_k127_4265301_12 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 334.0
DTH2_k127_4265301_13 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 307.0
DTH2_k127_4265301_14 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000002913 224.0
DTH2_k127_4265301_15 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000000000000000006536 211.0
DTH2_k127_4265301_16 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000000000000000004557 161.0
DTH2_k127_4265301_17 DNA mediated transformation - - - 0.000000000000000000000000000000000001278 147.0
DTH2_k127_4265301_18 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000001946 134.0
DTH2_k127_4265301_19 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000003894 130.0
DTH2_k127_4265301_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.083e-215 680.0
DTH2_k127_4265301_20 FMN binding - - - 0.0000000000000000000000000000006389 128.0
DTH2_k127_4265301_21 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000002495 105.0
DTH2_k127_4265301_22 Phosphopantetheine attachment site - - - 0.000000000000000005392 94.0
DTH2_k127_4265301_23 membrane - - - 0.000000001312 64.0
DTH2_k127_4265301_24 - - - - 0.000004923 53.0
DTH2_k127_4265301_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 539.0
DTH2_k127_4265301_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 503.0
DTH2_k127_4265301_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 503.0
DTH2_k127_4265301_6 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 489.0
DTH2_k127_4265301_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 471.0
DTH2_k127_4265301_8 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 457.0
DTH2_k127_4265301_9 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 427.0
DTH2_k127_4265380_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1335.0
DTH2_k127_4265380_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.051e-253 798.0
DTH2_k127_4265380_10 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 478.0
DTH2_k127_4265380_11 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 477.0
DTH2_k127_4265380_12 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
DTH2_k127_4265380_13 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 457.0
DTH2_k127_4265380_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 454.0
DTH2_k127_4265380_15 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 436.0
DTH2_k127_4265380_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 422.0
DTH2_k127_4265380_17 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
DTH2_k127_4265380_18 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 357.0
DTH2_k127_4265380_19 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 354.0
DTH2_k127_4265380_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 4.819e-241 765.0
DTH2_k127_4265380_20 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 359.0
DTH2_k127_4265380_21 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 349.0
DTH2_k127_4265380_22 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 348.0
DTH2_k127_4265380_23 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 334.0
DTH2_k127_4265380_24 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 299.0
DTH2_k127_4265380_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 305.0
DTH2_k127_4265380_26 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 298.0
DTH2_k127_4265380_27 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000107 268.0
DTH2_k127_4265380_28 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
DTH2_k127_4265380_29 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
DTH2_k127_4265380_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.089e-200 642.0
DTH2_k127_4265380_30 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.0000000000000000000000000000000000000000000000000000000000000005113 226.0
DTH2_k127_4265380_31 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000005823 198.0
DTH2_k127_4265380_32 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000001235 193.0
DTH2_k127_4265380_33 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000007956 194.0
DTH2_k127_4265380_34 PFAM Secreted repeat of - - - 0.000000000000000000000000000000000000000000000000005347 188.0
DTH2_k127_4265380_35 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000000004052 167.0
DTH2_k127_4265380_36 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000001447 156.0
DTH2_k127_4265380_37 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000005685 154.0
DTH2_k127_4265380_38 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000004119 157.0
DTH2_k127_4265380_39 Preprotein translocase K03210 - - 0.00000000000000000000000000000001873 130.0
DTH2_k127_4265380_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 583.0
DTH2_k127_4265380_40 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000002299 118.0
DTH2_k127_4265380_41 diguanylate cyclase - - - 0.00000000000000005215 89.0
DTH2_k127_4265380_42 Cytochrome B561 - - - 0.00000000000000233 77.0
DTH2_k127_4265380_5 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 563.0
DTH2_k127_4265380_6 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 519.0
DTH2_k127_4265380_7 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 517.0
DTH2_k127_4265380_8 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 494.0
DTH2_k127_4265380_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 489.0
DTH2_k127_4358716_0 FAD linked oxidase domain protein - - - 0.0 1999.0
DTH2_k127_4358716_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.581e-266 834.0
DTH2_k127_4358716_10 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
DTH2_k127_4358716_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 604.0
DTH2_k127_4358716_12 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 586.0
DTH2_k127_4358716_13 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 574.0
DTH2_k127_4358716_14 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 589.0
DTH2_k127_4358716_15 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 548.0
DTH2_k127_4358716_16 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 545.0
DTH2_k127_4358716_17 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 514.0
DTH2_k127_4358716_18 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 492.0
DTH2_k127_4358716_19 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 475.0
DTH2_k127_4358716_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 5.506e-243 758.0
DTH2_k127_4358716_20 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 466.0
DTH2_k127_4358716_21 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 470.0
DTH2_k127_4358716_22 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 403.0
DTH2_k127_4358716_23 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 374.0
DTH2_k127_4358716_24 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 359.0
DTH2_k127_4358716_25 PFAM Serine threonine protein kinase-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 377.0
DTH2_k127_4358716_26 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 349.0
DTH2_k127_4358716_27 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 334.0
DTH2_k127_4358716_28 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 324.0
DTH2_k127_4358716_29 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
DTH2_k127_4358716_3 Ammonium transporter K03320 - - 3.404e-230 726.0
DTH2_k127_4358716_30 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
DTH2_k127_4358716_31 Lysine exporter protein (Lyse ygga) K11250 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 292.0
DTH2_k127_4358716_32 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
DTH2_k127_4358716_33 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000259 285.0
DTH2_k127_4358716_34 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005855 271.0
DTH2_k127_4358716_35 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 266.0
DTH2_k127_4358716_36 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002321 274.0
DTH2_k127_4358716_37 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000005852 269.0
DTH2_k127_4358716_38 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000249 261.0
DTH2_k127_4358716_39 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
DTH2_k127_4358716_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.217e-225 705.0
DTH2_k127_4358716_40 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
DTH2_k127_4358716_41 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000001903 258.0
DTH2_k127_4358716_42 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004816 248.0
DTH2_k127_4358716_43 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003659 244.0
DTH2_k127_4358716_44 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000001468 254.0
DTH2_k127_4358716_45 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
DTH2_k127_4358716_46 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002113 237.0
DTH2_k127_4358716_47 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003228 237.0
DTH2_k127_4358716_48 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
DTH2_k127_4358716_49 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000003421 203.0
DTH2_k127_4358716_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.011e-214 676.0
DTH2_k127_4358716_50 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000002158 195.0
DTH2_k127_4358716_51 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000368 188.0
DTH2_k127_4358716_52 HIT domain - - - 0.00000000000000000000000000000000000000000000001003 176.0
DTH2_k127_4358716_53 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000002361 179.0
DTH2_k127_4358716_54 Ferredoxin - - - 0.0000000000000000000000000000000000000000000007181 167.0
DTH2_k127_4358716_55 SMART Transport-associated and nodulation region - - - 0.00000000000000000000000000000000000000000087 164.0
DTH2_k127_4358716_56 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000001503 164.0
DTH2_k127_4358716_57 - - - - 0.000000000000000000000000000000000000005781 157.0
DTH2_k127_4358716_58 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000000007525 152.0
DTH2_k127_4358716_59 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000817 156.0
DTH2_k127_4358716_6 Cell shape determining protein, MreB Mrl family K03569 - - 6.885e-199 624.0
DTH2_k127_4358716_60 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000001268 153.0
DTH2_k127_4358716_61 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000004478 137.0
DTH2_k127_4358716_62 - - - - 0.00000000000000000000000000000004419 127.0
DTH2_k127_4358716_63 Transcriptional regulator - - - 0.0000000000000000000000000000005068 126.0
DTH2_k127_4358716_64 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000012 121.0
DTH2_k127_4358716_65 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000146 119.0
DTH2_k127_4358716_66 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000001474 119.0
DTH2_k127_4358716_67 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001659 123.0
DTH2_k127_4358716_68 - - - - 0.0000000000000000000000000004954 122.0
DTH2_k127_4358716_69 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000001378 114.0
DTH2_k127_4358716_7 Glutamate-cysteine ligase K01919 - 6.3.2.2 7.947e-199 629.0
DTH2_k127_4358716_70 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000006066 116.0
DTH2_k127_4358716_72 Membrane fusogenic activity K09806 - - 0.0000000000000000001933 90.0
DTH2_k127_4358716_73 cytochrome complex assembly - - - 0.00000000001549 75.0
DTH2_k127_4358716_74 PFAM Sporulation domain protein - - - 0.00000000001709 74.0
DTH2_k127_4358716_75 - - - - 0.0000000004963 67.0
DTH2_k127_4358716_76 Belongs to the 'phage' integrase family - - - 0.00000001201 57.0
DTH2_k127_4358716_8 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.868e-194 613.0
DTH2_k127_4358716_9 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 602.0
DTH2_k127_4508876_0 COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B K13482 - 1.17.1.4 0.0 1184.0
DTH2_k127_4508876_1 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 3.56e-322 992.0
DTH2_k127_4508876_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 516.0
DTH2_k127_4508876_11 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
DTH2_k127_4508876_12 LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 470.0
DTH2_k127_4508876_13 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 455.0
DTH2_k127_4508876_14 signal transduction protein containing sensor and EAL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 331.0
DTH2_k127_4508876_15 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 318.0
DTH2_k127_4508876_16 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 303.0
DTH2_k127_4508876_17 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006022 285.0
DTH2_k127_4508876_18 Carboxylesterase family K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 273.0
DTH2_k127_4508876_19 Nucleoside-binding outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005108 221.0
DTH2_k127_4508876_2 transport systems, ATPase components K02056 - 3.6.3.17 7.104e-260 809.0
DTH2_k127_4508876_20 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000000004078 186.0
DTH2_k127_4508876_21 FCD - - - 0.0000000000000000000000000000000000000000000000006677 184.0
DTH2_k127_4508876_22 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000005917 174.0
DTH2_k127_4508876_23 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000007471 153.0
DTH2_k127_4508876_24 Glycine-zipper domain - - - 0.000000000000000000000000000000000005886 145.0
DTH2_k127_4508876_25 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000001041 150.0
DTH2_k127_4508876_26 - - - - 0.0000000000000000000000561 104.0
DTH2_k127_4508876_27 - - - - 0.00000000000000001089 91.0
DTH2_k127_4508876_28 Dienelactone hydrolase family - - - 0.000000000002032 75.0
DTH2_k127_4508876_29 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000009437 57.0
DTH2_k127_4508876_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.32e-239 759.0
DTH2_k127_4508876_30 Domain of unknown function (DUF4124) - - - 0.000002082 56.0
DTH2_k127_4508876_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00002025 51.0
DTH2_k127_4508876_32 sodium:proton antiporter activity K03316 - - 0.00006026 50.0
DTH2_k127_4508876_33 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.0008015 48.0
DTH2_k127_4508876_4 peptidase dimerisation domain protein - - - 2.892e-207 651.0
DTH2_k127_4508876_5 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 4.996e-196 623.0
DTH2_k127_4508876_6 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 599.0
DTH2_k127_4508876_7 deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 589.0
DTH2_k127_4508876_8 Pfam:DUF989 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 584.0
DTH2_k127_4508876_9 Basic membrane lipoprotein K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 529.0
DTH2_k127_4514083_0 surface antigen variable number repeat protein K07001 - - 2.951e-295 923.0
DTH2_k127_4514083_1 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 551.0
DTH2_k127_4514083_10 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000000000001884 166.0
DTH2_k127_4514083_11 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000001712 131.0
DTH2_k127_4514083_12 Sodium Bile acid symporter family - - - 0.0000000000000000002977 98.0
DTH2_k127_4514083_13 Protein of unknown function (DUF2783) - - - 0.0000000000000006719 79.0
DTH2_k127_4514083_14 secondary active sulfate transmembrane transporter activity K03321 - - 0.00000000002542 65.0
DTH2_k127_4514083_2 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 543.0
DTH2_k127_4514083_3 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 391.0
DTH2_k127_4514083_4 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 367.0
DTH2_k127_4514083_5 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
DTH2_k127_4514083_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005404 260.0
DTH2_k127_4514083_7 phosphinothricin N-acetyltransferase activity K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
DTH2_k127_4514083_8 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000002257 190.0
DTH2_k127_4514083_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001057 179.0
DTH2_k127_45365_0 oxidoreductase K04090 - 1.2.7.8 0.0 1461.0
DTH2_k127_45365_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1043.0
DTH2_k127_45365_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
DTH2_k127_45365_11 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 567.0
DTH2_k127_45365_12 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 559.0
DTH2_k127_45365_13 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 564.0
DTH2_k127_45365_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 548.0
DTH2_k127_45365_15 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 491.0
DTH2_k127_45365_16 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 464.0
DTH2_k127_45365_17 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 432.0
DTH2_k127_45365_18 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 412.0
DTH2_k127_45365_19 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 387.0
DTH2_k127_45365_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.963e-309 967.0
DTH2_k127_45365_20 KR domain K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 372.0
DTH2_k127_45365_21 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 366.0
DTH2_k127_45365_22 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 362.0
DTH2_k127_45365_23 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 360.0
DTH2_k127_45365_24 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
DTH2_k127_45365_25 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 337.0
DTH2_k127_45365_26 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 327.0
DTH2_k127_45365_27 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005932 280.0
DTH2_k127_45365_28 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005298 276.0
DTH2_k127_45365_29 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001275 261.0
DTH2_k127_45365_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.723e-291 914.0
DTH2_k127_45365_30 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
DTH2_k127_45365_31 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000538 258.0
DTH2_k127_45365_32 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000002404 252.0
DTH2_k127_45365_33 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000003772 235.0
DTH2_k127_45365_34 Tetratricopeptide repeat K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000004207 238.0
DTH2_k127_45365_35 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
DTH2_k127_45365_36 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000004174 235.0
DTH2_k127_45365_37 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001834 225.0
DTH2_k127_45365_38 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
DTH2_k127_45365_39 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000002519 214.0
DTH2_k127_45365_4 A predicted alpha-helical domain with a conserved ER motif. - - - 8.884e-262 827.0
DTH2_k127_45365_40 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000005638 203.0
DTH2_k127_45365_41 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000471 211.0
DTH2_k127_45365_42 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000003049 193.0
DTH2_k127_45365_43 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000004759 185.0
DTH2_k127_45365_44 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000003401 180.0
DTH2_k127_45365_45 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000001835 177.0
DTH2_k127_45365_46 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000002783 170.0
DTH2_k127_45365_47 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000312 165.0
DTH2_k127_45365_48 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000005297 158.0
DTH2_k127_45365_49 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000001806 147.0
DTH2_k127_45365_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.981e-257 812.0
DTH2_k127_45365_50 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000004239 142.0
DTH2_k127_45365_51 Helix-turn-helix domain K15539 - - 0.00000000000000000000000000003728 130.0
DTH2_k127_45365_52 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000003624 106.0
DTH2_k127_45365_53 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000001749 86.0
DTH2_k127_45365_54 protein conserved in bacteria K09937 - - 0.00000000000009749 74.0
DTH2_k127_45365_55 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000021 64.0
DTH2_k127_45365_56 dehydrogenase - - - 0.00006767 49.0
DTH2_k127_45365_6 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 1.949e-237 740.0
DTH2_k127_45365_7 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.546e-219 687.0
DTH2_k127_45365_8 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 7.389e-216 676.0
DTH2_k127_45365_9 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.557e-199 629.0
DTH2_k127_457974_0 PFAM carboxyl transferase K01615 - 4.1.1.70 1.21e-297 923.0
DTH2_k127_457974_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.615e-266 829.0
DTH2_k127_457974_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 485.0
DTH2_k127_457974_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 429.0
DTH2_k127_457974_12 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 400.0
DTH2_k127_457974_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 406.0
DTH2_k127_457974_14 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 376.0
DTH2_k127_457974_15 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 362.0
DTH2_k127_457974_16 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 342.0
DTH2_k127_457974_17 HsdM N-terminal domain K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 294.0
DTH2_k127_457974_18 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 291.0
DTH2_k127_457974_19 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001645 275.0
DTH2_k127_457974_2 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.109e-254 790.0
DTH2_k127_457974_20 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003884 231.0
DTH2_k127_457974_21 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000001341 220.0
DTH2_k127_457974_22 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
DTH2_k127_457974_23 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000005645 182.0
DTH2_k127_457974_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000002478 142.0
DTH2_k127_457974_25 Domain of unknown function (DUF4387) - - - 0.000000000000000000000000000581 123.0
DTH2_k127_457974_26 Biotin-requiring enzyme - - - 0.000000000000000000002547 94.0
DTH2_k127_457974_27 - - - - 0.0000000000000143 85.0
DTH2_k127_457974_28 PFAM conserved - - - 0.0000000000000223 82.0
DTH2_k127_457974_29 cellulase activity - - - 0.0000005462 63.0
DTH2_k127_457974_3 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.124e-240 752.0
DTH2_k127_457974_30 Bacterial Ig-like domain (group 3) - - - 0.00001525 58.0
DTH2_k127_457974_4 Aldehyde dehydrogenase family K15514 - 1.2.1.77 4.372e-214 676.0
DTH2_k127_457974_5 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 7.792e-212 664.0
DTH2_k127_457974_6 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 595.0
DTH2_k127_457974_7 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 560.0
DTH2_k127_457974_8 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 526.0
DTH2_k127_457974_9 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 495.0
DTH2_k127_4588093_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1213.0
DTH2_k127_4588093_1 GMP synthase C terminal domain K01951 - 6.3.5.2 2.621e-282 875.0
DTH2_k127_4588093_10 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000003825 221.0
DTH2_k127_4588093_11 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000007189 184.0
DTH2_k127_4588093_12 Oligoketide cyclase lipid transport protein - - - 0.000000000000000000000000000000000000000001066 161.0
DTH2_k127_4588093_13 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000001246 155.0
DTH2_k127_4588093_14 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000008956 143.0
DTH2_k127_4588093_15 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000872 132.0
DTH2_k127_4588093_16 Domain of unknown function (DUF4124) - - - 0.00000000000000003639 90.0
DTH2_k127_4588093_17 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000001194 75.0
DTH2_k127_4588093_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.983e-241 755.0
DTH2_k127_4588093_3 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 498.0
DTH2_k127_4588093_4 C-terminal region of band_7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
DTH2_k127_4588093_5 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 421.0
DTH2_k127_4588093_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 403.0
DTH2_k127_4588093_7 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 395.0
DTH2_k127_4588093_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 347.0
DTH2_k127_4588093_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000009085 233.0
DTH2_k127_4606802_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 8.39e-209 662.0
DTH2_k127_4606802_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 526.0
DTH2_k127_4606802_2 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
DTH2_k127_4606802_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 440.0
DTH2_k127_4606802_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005549 244.0
DTH2_k127_4606802_5 PFAM cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
DTH2_k127_4606802_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000001747 192.0
DTH2_k127_4606802_7 Belongs to the frataxin family K06202 - - 0.0000000000000000000000000000000004626 133.0
DTH2_k127_4623641_0 2Fe-2S iron-sulfur cluster binding domain K22086 - 1.5.99.5 1.377e-247 788.0
DTH2_k127_4623641_1 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 490.0
DTH2_k127_4623641_2 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 443.0
DTH2_k127_4623641_3 abc transporter atp-binding protein K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 399.0
DTH2_k127_4623641_4 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 366.0
DTH2_k127_4623641_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
DTH2_k127_4623641_6 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
DTH2_k127_4623641_7 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000002303 146.0
DTH2_k127_4623641_8 Sarcosine oxidase, gamma subunit K00305 - 1.5.3.1 0.00000000000000000000402 101.0
DTH2_k127_473007_0 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 559.0
DTH2_k127_473007_1 Amino-transferase class IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
DTH2_k127_473007_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 298.0
DTH2_k127_473007_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003076 255.0
DTH2_k127_473007_4 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001117 237.0
DTH2_k127_473007_5 - - - - 0.0000000000000000000000000000000000001576 147.0
DTH2_k127_4842407_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1455.0
DTH2_k127_4842407_1 Tetratricopeptide repeat - - - 0.0 1208.0
DTH2_k127_4842407_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 439.0
DTH2_k127_4842407_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 432.0
DTH2_k127_4842407_12 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 432.0
DTH2_k127_4842407_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 415.0
DTH2_k127_4842407_14 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 368.0
DTH2_k127_4842407_15 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 357.0
DTH2_k127_4842407_16 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 355.0
DTH2_k127_4842407_17 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
DTH2_k127_4842407_18 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 327.0
DTH2_k127_4842407_19 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 335.0
DTH2_k127_4842407_2 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 7.026e-289 903.0
DTH2_k127_4842407_20 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 290.0
DTH2_k127_4842407_21 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 298.0
DTH2_k127_4842407_22 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 302.0
DTH2_k127_4842407_23 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
DTH2_k127_4842407_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001314 277.0
DTH2_k127_4842407_25 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 280.0
DTH2_k127_4842407_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003508 275.0
DTH2_k127_4842407_27 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007281 257.0
DTH2_k127_4842407_28 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
DTH2_k127_4842407_29 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
DTH2_k127_4842407_3 Tetratricopeptide repeat - - - 2.646e-233 739.0
DTH2_k127_4842407_30 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
DTH2_k127_4842407_31 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008592 244.0
DTH2_k127_4842407_32 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
DTH2_k127_4842407_33 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000208 238.0
DTH2_k127_4842407_34 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
DTH2_k127_4842407_35 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000008606 223.0
DTH2_k127_4842407_36 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000001988 227.0
DTH2_k127_4842407_37 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001287 220.0
DTH2_k127_4842407_38 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000000000000000001386 209.0
DTH2_k127_4842407_39 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000008851 219.0
DTH2_k127_4842407_4 Cyclohexanecarboxylate-CoA ligase K04116,K12507 - - 5.639e-223 704.0
DTH2_k127_4842407_40 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000002162 204.0
DTH2_k127_4842407_41 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000006374 189.0
DTH2_k127_4842407_42 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000003358 179.0
DTH2_k127_4842407_43 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000002767 162.0
DTH2_k127_4842407_44 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000003885 154.0
DTH2_k127_4842407_45 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000000000009934 138.0
DTH2_k127_4842407_46 - - - - 0.0000000000000000000000000000003211 126.0
DTH2_k127_4842407_47 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000004675 124.0
DTH2_k127_4842407_48 - - - - 0.0000000000000003285 94.0
DTH2_k127_4842407_49 Transposase IS4 family - - - 0.000001428 55.0
DTH2_k127_4842407_5 COG0277 FAD FMN-containing dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 544.0
DTH2_k127_4842407_50 Abortive infection C-terminus - - - 0.000001603 56.0
DTH2_k127_4842407_51 ATPases associated with a variety of cellular activities K01996 - - 0.000009895 55.0
DTH2_k127_4842407_52 Domain of unknown function (DUF4124) - - - 0.0002306 49.0
DTH2_k127_4842407_6 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 516.0
DTH2_k127_4842407_7 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 499.0
DTH2_k127_4842407_8 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 468.0
DTH2_k127_4842407_9 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 458.0
DTH2_k127_4877386_0 Dehydratase family K13875 - 4.2.1.25 3.654e-302 933.0
DTH2_k127_4877386_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 513.0
DTH2_k127_4877386_2 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 480.0
DTH2_k127_4877386_3 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 442.0
DTH2_k127_4877386_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 431.0
DTH2_k127_4877386_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 343.0
DTH2_k127_4877386_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000001218 121.0
DTH2_k127_5041122_0 Tricorn protease homolog K08676 - - 0.0 1105.0
DTH2_k127_5041122_1 Male sterility protein - - - 0.0 1005.0
DTH2_k127_5041122_10 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 6.349e-203 640.0
DTH2_k127_5041122_11 ABC-type Fe3 transport system, periplasmic component - - - 5.145e-196 620.0
DTH2_k127_5041122_12 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 601.0
DTH2_k127_5041122_13 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 592.0
DTH2_k127_5041122_14 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 561.0
DTH2_k127_5041122_15 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 499.0
DTH2_k127_5041122_16 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 499.0
DTH2_k127_5041122_17 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 488.0
DTH2_k127_5041122_18 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 473.0
DTH2_k127_5041122_19 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 457.0
DTH2_k127_5041122_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.82e-318 981.0
DTH2_k127_5041122_20 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 430.0
DTH2_k127_5041122_21 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 398.0
DTH2_k127_5041122_22 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 383.0
DTH2_k127_5041122_23 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 365.0
DTH2_k127_5041122_24 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 341.0
DTH2_k127_5041122_25 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 324.0
DTH2_k127_5041122_26 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 324.0
DTH2_k127_5041122_27 Threonyl alanyl tRNA synthetase K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 326.0
DTH2_k127_5041122_28 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 319.0
DTH2_k127_5041122_29 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 319.0
DTH2_k127_5041122_3 ABC-type Fe3 transport system permease component K02011 - - 2.159e-250 788.0
DTH2_k127_5041122_30 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 319.0
DTH2_k127_5041122_31 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 282.0
DTH2_k127_5041122_32 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 281.0
DTH2_k127_5041122_33 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 277.0
DTH2_k127_5041122_34 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001766 269.0
DTH2_k127_5041122_35 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000172 254.0
DTH2_k127_5041122_36 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
DTH2_k127_5041122_37 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
DTH2_k127_5041122_38 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000002359 209.0
DTH2_k127_5041122_39 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000004909 200.0
DTH2_k127_5041122_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 4.342e-248 779.0
DTH2_k127_5041122_40 - - - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
DTH2_k127_5041122_41 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000005958 181.0
DTH2_k127_5041122_42 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000002138 181.0
DTH2_k127_5041122_43 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000007758 175.0
DTH2_k127_5041122_44 PFAM poly granule associated family protein - - - 0.000000000000000000000000000000000000002323 152.0
DTH2_k127_5041122_45 acyl-coA-binding protein - - - 0.000000000000000000000000000000000322 134.0
DTH2_k127_5041122_46 Twin-arginine translocation pathway signal protein - - - 0.0000000000000000000000000000000004461 138.0
DTH2_k127_5041122_47 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000002116 131.0
DTH2_k127_5041122_48 PFAM RDD domain containing protein - - - 0.0000000000000000000000000002122 121.0
DTH2_k127_5041122_49 - - - - 0.000000000000000000000004775 111.0
DTH2_k127_5041122_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 9.032e-228 722.0
DTH2_k127_5041122_50 Protein of unknown function (DUF3106) - - - 0.000000000000000004375 91.0
DTH2_k127_5041122_51 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000001207 86.0
DTH2_k127_5041122_52 Protein of unknown function (DUF3619) - - - 0.0000000001122 70.0
DTH2_k127_5041122_53 Putative transposase - - - 0.0000000009315 62.0
DTH2_k127_5041122_54 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.0000005545 54.0
DTH2_k127_5041122_6 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 3.589e-224 707.0
DTH2_k127_5041122_7 GMC oxidoreductase - - - 2.639e-222 701.0
DTH2_k127_5041122_8 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.627e-213 679.0
DTH2_k127_5041122_9 Branched-chain amino acid transport system / permease component K01997,K01998 - - 1.608e-209 667.0
DTH2_k127_5052701_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.836e-215 673.0
DTH2_k127_5052701_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 500.0
DTH2_k127_5052701_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000003335 57.0
DTH2_k127_509061_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000198 278.0
DTH2_k127_5141714_0 PFAM Integrase catalytic - - - 1.24e-275 856.0
DTH2_k127_5141714_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 432.0
DTH2_k127_5141714_2 PFAM IstB domain protein ATP-binding protein - - - 0.00000004651 57.0
DTH2_k127_5160561_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 1.54e-284 883.0
DTH2_k127_5160561_1 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 1.44e-277 862.0
DTH2_k127_5160561_10 TIGRFAM taurine ABC transporter, periplasmic binding protein K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 508.0
DTH2_k127_5160561_11 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 522.0
DTH2_k127_5160561_12 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 494.0
DTH2_k127_5160561_13 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 497.0
DTH2_k127_5160561_14 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 467.0
DTH2_k127_5160561_15 ABC transporter K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 464.0
DTH2_k127_5160561_16 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 451.0
DTH2_k127_5160561_17 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 445.0
DTH2_k127_5160561_18 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 452.0
DTH2_k127_5160561_19 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 435.0
DTH2_k127_5160561_2 Sulfatase K01130 - 3.1.6.1 1.404e-262 824.0
DTH2_k127_5160561_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 394.0
DTH2_k127_5160561_21 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 378.0
DTH2_k127_5160561_22 PFAM Helix-turn-helix, type 11 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 304.0
DTH2_k127_5160561_23 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 315.0
DTH2_k127_5160561_24 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006409 281.0
DTH2_k127_5160561_25 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001555 249.0
DTH2_k127_5160561_26 Transcriptional regulator K19333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006388 254.0
DTH2_k127_5160561_27 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001451 214.0
DTH2_k127_5160561_28 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000001113 207.0
DTH2_k127_5160561_29 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000379 201.0
DTH2_k127_5160561_3 FAD dependent oxidoreductase K07256 - - 5.927e-255 791.0
DTH2_k127_5160561_30 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000008436 186.0
DTH2_k127_5160561_31 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000003735 196.0
DTH2_k127_5160561_32 PIN domain - - - 0.0000000000000000000000000000000000000000000008893 168.0
DTH2_k127_5160561_33 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000001105 178.0
DTH2_k127_5160561_34 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000001625 160.0
DTH2_k127_5160561_35 Helix-turn-helix domain - - - 0.0000000000000000000000000000001972 126.0
DTH2_k127_5160561_38 Post-segregation antitoxin CcdA K19164 - - 0.00000000000000002898 90.0
DTH2_k127_5160561_39 Domain of unknown function (DUF4437) - - - 0.00000002613 56.0
DTH2_k127_5160561_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.498e-214 676.0
DTH2_k127_5160561_41 SpoVT / AbrB like domain - - - 0.00008191 48.0
DTH2_k127_5160561_5 Aminotransferase K00375 - - 2.393e-210 667.0
DTH2_k127_5160561_6 Dehydrogenase K15515 - 1.2.1.81 1.664e-208 657.0
DTH2_k127_5160561_7 Group II intron, maturase-specific domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 582.0
DTH2_k127_5160561_8 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 580.0
DTH2_k127_5160561_9 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 512.0
DTH2_k127_5204654_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 301.0
DTH2_k127_5204654_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000001451 205.0
DTH2_k127_5234357_0 GAF domain - - - 6.613e-230 720.0
DTH2_k127_5234357_1 Prokaryotic N-terminal methylation motif K02650 - - 0.00002068 48.0
DTH2_k127_5298606_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 4.91e-273 853.0
DTH2_k127_5298606_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 576.0
DTH2_k127_5298606_10 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000307 175.0
DTH2_k127_5298606_11 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000001623 162.0
DTH2_k127_5298606_12 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000005773 145.0
DTH2_k127_5298606_13 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000004039 130.0
DTH2_k127_5298606_14 Protein of unknown function (DUF2905) - - - 0.0000000000000000477 81.0
DTH2_k127_5298606_15 pyrroloquinoline quinone binding K12287 - - 0.0000000000003755 83.0
DTH2_k127_5298606_2 Soluble lytic murein K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 569.0
DTH2_k127_5298606_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 554.0
DTH2_k127_5298606_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 461.0
DTH2_k127_5298606_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 379.0
DTH2_k127_5298606_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 327.0
DTH2_k127_5298606_7 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
DTH2_k127_5298606_8 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 323.0
DTH2_k127_5298606_9 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005161 263.0
DTH2_k127_5302902_0 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
DTH2_k127_5302902_1 - - - - 0.000000000000000000000000000000000000000000000000000000002166 202.0
DTH2_k127_5302902_2 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00007494 46.0
DTH2_k127_5312682_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2516.0
DTH2_k127_5312682_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 4.652e-274 866.0
DTH2_k127_5312682_10 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 531.0
DTH2_k127_5312682_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 525.0
DTH2_k127_5312682_12 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 456.0
DTH2_k127_5312682_13 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 451.0
DTH2_k127_5312682_14 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 441.0
DTH2_k127_5312682_15 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 434.0
DTH2_k127_5312682_16 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 434.0
DTH2_k127_5312682_17 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 416.0
DTH2_k127_5312682_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 411.0
DTH2_k127_5312682_19 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 401.0
DTH2_k127_5312682_2 CoA binding domain K09181 - - 2.331e-256 808.0
DTH2_k127_5312682_20 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 394.0
DTH2_k127_5312682_21 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
DTH2_k127_5312682_22 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 376.0
DTH2_k127_5312682_23 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
DTH2_k127_5312682_24 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 364.0
DTH2_k127_5312682_25 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 337.0
DTH2_k127_5312682_26 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 339.0
DTH2_k127_5312682_27 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 328.0
DTH2_k127_5312682_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 316.0
DTH2_k127_5312682_29 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 311.0
DTH2_k127_5312682_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.2e-256 796.0
DTH2_k127_5312682_30 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
DTH2_k127_5312682_31 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000447 279.0
DTH2_k127_5312682_32 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
DTH2_k127_5312682_33 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 276.0
DTH2_k127_5312682_34 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
DTH2_k127_5312682_35 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008835 276.0
DTH2_k127_5312682_36 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000003352 266.0
DTH2_k127_5312682_37 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004444 256.0
DTH2_k127_5312682_38 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001582 263.0
DTH2_k127_5312682_39 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
DTH2_k127_5312682_4 type IV pilus secretin PilQ K02666 - - 1.108e-230 739.0
DTH2_k127_5312682_40 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005771 247.0
DTH2_k127_5312682_41 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000002497 230.0
DTH2_k127_5312682_42 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000006253 213.0
DTH2_k127_5312682_43 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000002298 209.0
DTH2_k127_5312682_44 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000000003291 192.0
DTH2_k127_5312682_45 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000002329 191.0
DTH2_k127_5312682_46 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000006532 188.0
DTH2_k127_5312682_47 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000006812 179.0
DTH2_k127_5312682_48 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000003533 181.0
DTH2_k127_5312682_49 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000001708 181.0
DTH2_k127_5312682_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 6.01e-220 691.0
DTH2_k127_5312682_50 Cupin 2, conserved barrel domain protein K11312 - - 0.00000000000000000000000000000000000000000000001749 176.0
DTH2_k127_5312682_51 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000003376 172.0
DTH2_k127_5312682_52 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000001482 166.0
DTH2_k127_5312682_53 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000000002369 147.0
DTH2_k127_5312682_54 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000000000000001197 144.0
DTH2_k127_5312682_55 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000009591 144.0
DTH2_k127_5312682_56 protein domain associated with - - - 0.0000000000000000000000000000000001305 144.0
DTH2_k127_5312682_57 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000002352 123.0
DTH2_k127_5312682_58 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000002607 109.0
DTH2_k127_5312682_59 Large extracellular alpha-helical protein - - - 0.0000000000000000001254 104.0
DTH2_k127_5312682_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.896e-209 660.0
DTH2_k127_5312682_60 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000002253 91.0
DTH2_k127_5312682_61 NTP binding protein (Contains STAS domain) K04749,K07122 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716 - 0.000000000000004601 78.0
DTH2_k127_5312682_62 Transposase - - - 0.000000000000004969 81.0
DTH2_k127_5312682_63 FR47-like protein K06976 - - 0.0000000000008401 73.0
DTH2_k127_5312682_65 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0003852 45.0
DTH2_k127_5312682_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 580.0
DTH2_k127_5312682_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 563.0
DTH2_k127_5312682_9 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009603 537.0
DTH2_k127_5320365_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1384.0
DTH2_k127_5320365_1 Aminotransferase K14261 - - 4.698e-227 707.0
DTH2_k127_5320365_10 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000002057 160.0
DTH2_k127_5320365_11 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000003411 158.0
DTH2_k127_5320365_12 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.00000000000000000000001475 107.0
DTH2_k127_5320365_13 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000001677 93.0
DTH2_k127_5320365_14 Tetratricopeptide repeat - - - 0.000000001835 70.0
DTH2_k127_5320365_15 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000004682 61.0
DTH2_k127_5320365_2 SMART Nucleotide binding protein, PINc K07175 - - 1.824e-206 655.0
DTH2_k127_5320365_3 Threonine synthase K01733 - 4.2.3.1 3.982e-197 625.0
DTH2_k127_5320365_4 homoserine dehydrogenase K00003 - 1.1.1.3 8.799e-197 623.0
DTH2_k127_5320365_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 529.0
DTH2_k127_5320365_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 317.0
DTH2_k127_5320365_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000368 243.0
DTH2_k127_5320365_8 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000001114 224.0
DTH2_k127_5320365_9 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000004424 184.0
DTH2_k127_5482154_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0 1011.0
DTH2_k127_5482154_1 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.848e-306 952.0
DTH2_k127_5482154_10 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 505.0
DTH2_k127_5482154_11 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 514.0
DTH2_k127_5482154_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 483.0
DTH2_k127_5482154_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 484.0
DTH2_k127_5482154_14 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
DTH2_k127_5482154_15 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 446.0
DTH2_k127_5482154_16 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 441.0
DTH2_k127_5482154_17 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 452.0
DTH2_k127_5482154_18 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 434.0
DTH2_k127_5482154_19 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 439.0
DTH2_k127_5482154_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.503e-287 897.0
DTH2_k127_5482154_20 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 430.0
DTH2_k127_5482154_21 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 424.0
DTH2_k127_5482154_22 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 417.0
DTH2_k127_5482154_23 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 351.0
DTH2_k127_5482154_24 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 340.0
DTH2_k127_5482154_25 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 336.0
DTH2_k127_5482154_26 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 331.0
DTH2_k127_5482154_27 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 326.0
DTH2_k127_5482154_28 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 325.0
DTH2_k127_5482154_29 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 304.0
DTH2_k127_5482154_3 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 1.759e-279 882.0
DTH2_k127_5482154_30 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 289.0
DTH2_k127_5482154_31 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
DTH2_k127_5482154_32 d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000951 280.0
DTH2_k127_5482154_33 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
DTH2_k127_5482154_34 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 252.0
DTH2_k127_5482154_35 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000028 239.0
DTH2_k127_5482154_36 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007962 242.0
DTH2_k127_5482154_37 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
DTH2_k127_5482154_38 - - - - 0.00000000000000000000000000000000000000000000000000000000000003897 222.0
DTH2_k127_5482154_39 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000005039 216.0
DTH2_k127_5482154_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.195e-259 817.0
DTH2_k127_5482154_41 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000001994 190.0
DTH2_k127_5482154_42 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000005754 188.0
DTH2_k127_5482154_43 regulatory - - - 0.000000000000000000000000000000000000000000000000001463 190.0
DTH2_k127_5482154_44 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000008189 184.0
DTH2_k127_5482154_45 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000006515 191.0
DTH2_k127_5482154_46 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000002978 179.0
DTH2_k127_5482154_47 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000001339 170.0
DTH2_k127_5482154_48 LemA family - - - 0.0000000000000000000000000000000000000000002747 166.0
DTH2_k127_5482154_49 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000001977 158.0
DTH2_k127_5482154_5 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 2.786e-211 665.0
DTH2_k127_5482154_50 Small Multidrug Resistance protein K03297 - - 0.000000000000000000000000000000000001095 145.0
DTH2_k127_5482154_51 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000001999 142.0
DTH2_k127_5482154_52 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000003372 135.0
DTH2_k127_5482154_53 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000002968 130.0
DTH2_k127_5482154_54 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000001331 121.0
DTH2_k127_5482154_55 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000001648 119.0
DTH2_k127_5482154_56 Nucleotidyltransferase domain K07076 - - 0.000000000000000000000000008027 114.0
DTH2_k127_5482154_57 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000001426 108.0
DTH2_k127_5482154_58 PFAM Small Multidrug Resistance protein K03297 - - 0.00000000000000000000003446 109.0
DTH2_k127_5482154_59 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000003638 92.0
DTH2_k127_5482154_6 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 577.0
DTH2_k127_5482154_60 HEPN domain - - - 0.00000000000000005126 87.0
DTH2_k127_5482154_61 PFAM MaoC domain protein dehydratase - - - 0.000000000000000428 80.0
DTH2_k127_5482154_62 - - - - 0.00000000005406 69.0
DTH2_k127_5482154_63 thiolester hydrolase activity K17362 - - 0.0000000001172 68.0
DTH2_k127_5482154_64 CotH kinase protein - - - 0.0000000001388 70.0
DTH2_k127_5482154_65 PFAM transposase, IS4 family protein - - - 0.000002064 51.0
DTH2_k127_5482154_7 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 567.0
DTH2_k127_5482154_8 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 542.0
DTH2_k127_5482154_9 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 520.0
DTH2_k127_5523521_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1324.0
DTH2_k127_5523521_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 3.168e-277 879.0
DTH2_k127_5523521_10 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 496.0
DTH2_k127_5523521_11 Lytic transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 458.0
DTH2_k127_5523521_12 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 416.0
DTH2_k127_5523521_13 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 411.0
DTH2_k127_5523521_14 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 379.0
DTH2_k127_5523521_15 PFAM ABC transporter related K10017,K10025 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 367.0
DTH2_k127_5523521_16 Ligated ion channel L-glutamate- and glycine-binding site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 336.0
DTH2_k127_5523521_17 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 332.0
DTH2_k127_5523521_18 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 331.0
DTH2_k127_5523521_19 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 327.0
DTH2_k127_5523521_2 ABC transporter transmembrane region K06147 - - 3.594e-275 865.0
DTH2_k127_5523521_20 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 317.0
DTH2_k127_5523521_21 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
DTH2_k127_5523521_22 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
DTH2_k127_5523521_23 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
DTH2_k127_5523521_24 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 294.0
DTH2_k127_5523521_25 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006932 271.0
DTH2_k127_5523521_26 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004664 269.0
DTH2_k127_5523521_27 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003174 269.0
DTH2_k127_5523521_28 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006013 273.0
DTH2_k127_5523521_29 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003134 249.0
DTH2_k127_5523521_3 FtsX-like permease family K02004 - - 9.806e-209 677.0
DTH2_k127_5523521_30 PFAM pyridoxamine 5-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
DTH2_k127_5523521_31 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000001312 225.0
DTH2_k127_5523521_32 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001351 226.0
DTH2_k127_5523521_33 Glyoxalase bleomycin resistance - - - 0.0000000000000000000000000000000000000000000000000009705 185.0
DTH2_k127_5523521_34 PFAM MAPEG family - - - 0.000000000000000000000000000000000003398 149.0
DTH2_k127_5523521_35 carbon monoxide dehydrogenase K09386 - - 0.000000000000000000000000000000000565 137.0
DTH2_k127_5523521_36 enzyme binding - - - 0.000000000000000000000000000001458 126.0
DTH2_k127_5523521_37 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000003488 112.0
DTH2_k127_5523521_38 Protein of unknown function (DUF1059) - - - 0.0000000000000000000000006435 106.0
DTH2_k127_5523521_39 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000002959 105.0
DTH2_k127_5523521_4 Peptidase C39 family K13409 - - 1.225e-205 664.0
DTH2_k127_5523521_40 IS66 Orf2 like protein - - - 0.000000000003405 71.0
DTH2_k127_5523521_41 nuclease K01174 - 3.1.31.1 0.00000001552 59.0
DTH2_k127_5523521_42 - - - - 0.00000006509 60.0
DTH2_k127_5523521_44 - - - - 0.0000001623 53.0
DTH2_k127_5523521_46 - - - - 0.00003017 46.0
DTH2_k127_5523521_47 PEP-CTERM motif - - - 0.00006128 52.0
DTH2_k127_5523521_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 599.0
DTH2_k127_5523521_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 544.0
DTH2_k127_5523521_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 516.0
DTH2_k127_5523521_8 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 522.0
DTH2_k127_5523521_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 496.0
DTH2_k127_5525700_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.77e-275 860.0
DTH2_k127_5525700_1 phenylacetic acid degradation protein paaN - - - 2.802e-258 807.0
DTH2_k127_5525700_10 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 380.0
DTH2_k127_5525700_11 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
DTH2_k127_5525700_12 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 369.0
DTH2_k127_5525700_13 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 366.0
DTH2_k127_5525700_14 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 367.0
DTH2_k127_5525700_15 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 306.0
DTH2_k127_5525700_16 Phenylacetic acid degradation protein PaaY K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 285.0
DTH2_k127_5525700_17 O-Methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001182 271.0
DTH2_k127_5525700_18 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001603 262.0
DTH2_k127_5525700_19 lipopolysaccharide heptosyltransferase I K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003842 267.0
DTH2_k127_5525700_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.172e-212 668.0
DTH2_k127_5525700_20 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
DTH2_k127_5525700_21 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000000000000000000000000000000002174 224.0
DTH2_k127_5525700_22 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
DTH2_k127_5525700_23 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.00000000000000000000000000000000000000000000000000002925 190.0
DTH2_k127_5525700_24 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000000000000000004114 178.0
DTH2_k127_5525700_25 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000001051 148.0
DTH2_k127_5525700_26 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000003997 115.0
DTH2_k127_5525700_27 - - - - 0.000000000000000001242 88.0
DTH2_k127_5525700_28 Histidine kinase - - - 0.0000007681 58.0
DTH2_k127_5525700_29 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00003284 48.0
DTH2_k127_5525700_3 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 584.0
DTH2_k127_5525700_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 596.0
DTH2_k127_5525700_5 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 584.0
DTH2_k127_5525700_6 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 502.0
DTH2_k127_5525700_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 465.0
DTH2_k127_5525700_8 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 416.0
DTH2_k127_5525700_9 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 399.0
DTH2_k127_5554333_0 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 297.0
DTH2_k127_5554333_1 5-oxoprolinase K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000002803 221.0
DTH2_k127_5633063_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1483.0
DTH2_k127_5633063_1 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1347.0
DTH2_k127_5633063_10 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.277e-219 687.0
DTH2_k127_5633063_11 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 4.926e-218 691.0
DTH2_k127_5633063_12 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.153e-215 679.0
DTH2_k127_5633063_13 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 4.473e-212 662.0
DTH2_k127_5633063_14 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.627e-208 654.0
DTH2_k127_5633063_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.633e-203 640.0
DTH2_k127_5633063_16 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 4.778e-202 638.0
DTH2_k127_5633063_17 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 606.0
DTH2_k127_5633063_18 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
DTH2_k127_5633063_19 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 593.0
DTH2_k127_5633063_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1281.0
DTH2_k127_5633063_20 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 598.0
DTH2_k127_5633063_21 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 584.0
DTH2_k127_5633063_22 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 567.0
DTH2_k127_5633063_23 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 560.0
DTH2_k127_5633063_24 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 556.0
DTH2_k127_5633063_25 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 567.0
DTH2_k127_5633063_26 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 551.0
DTH2_k127_5633063_27 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 556.0
DTH2_k127_5633063_28 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 543.0
DTH2_k127_5633063_29 Sigma-54 interaction domain K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 537.0
DTH2_k127_5633063_3 Malic enzyme K00029 - 1.1.1.40 0.0 1130.0
DTH2_k127_5633063_30 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 503.0
DTH2_k127_5633063_31 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 501.0
DTH2_k127_5633063_32 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 486.0
DTH2_k127_5633063_33 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 482.0
DTH2_k127_5633063_34 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 467.0
DTH2_k127_5633063_35 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 459.0
DTH2_k127_5633063_36 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 425.0
DTH2_k127_5633063_37 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 433.0
DTH2_k127_5633063_38 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 412.0
DTH2_k127_5633063_39 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 405.0
DTH2_k127_5633063_4 Belongs to the transketolase family K00615 - 2.2.1.1 1.437e-289 906.0
DTH2_k127_5633063_40 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 392.0
DTH2_k127_5633063_41 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
DTH2_k127_5633063_42 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
DTH2_k127_5633063_43 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 359.0
DTH2_k127_5633063_44 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 354.0
DTH2_k127_5633063_45 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 352.0
DTH2_k127_5633063_46 COG3293 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 329.0
DTH2_k127_5633063_47 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 326.0
DTH2_k127_5633063_48 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 332.0
DTH2_k127_5633063_49 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 309.0
DTH2_k127_5633063_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.458e-279 868.0
DTH2_k127_5633063_50 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 308.0
DTH2_k127_5633063_51 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
DTH2_k127_5633063_52 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 299.0
DTH2_k127_5633063_53 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 298.0
DTH2_k127_5633063_54 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 287.0
DTH2_k127_5633063_55 FHA Domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 293.0
DTH2_k127_5633063_56 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 287.0
DTH2_k127_5633063_57 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003502 280.0
DTH2_k127_5633063_58 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000354 254.0
DTH2_k127_5633063_59 TonB C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003335 251.0
DTH2_k127_5633063_6 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 8.391e-263 817.0
DTH2_k127_5633063_60 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000008731 239.0
DTH2_k127_5633063_61 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
DTH2_k127_5633063_62 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
DTH2_k127_5633063_63 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000001384 220.0
DTH2_k127_5633063_64 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
DTH2_k127_5633063_65 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000004628 225.0
DTH2_k127_5633063_66 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000009946 212.0
DTH2_k127_5633063_67 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000005222 207.0
DTH2_k127_5633063_68 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000114 189.0
DTH2_k127_5633063_69 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001559 189.0
DTH2_k127_5633063_7 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.605e-254 789.0
DTH2_k127_5633063_70 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000002823 193.0
DTH2_k127_5633063_71 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000001384 183.0
DTH2_k127_5633063_72 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000001636 185.0
DTH2_k127_5633063_73 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000104 166.0
DTH2_k127_5633063_74 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000082 155.0
DTH2_k127_5633063_75 YGGT family K02221 - - 0.0000000000000000000000000000000000000000491 158.0
DTH2_k127_5633063_76 mRNA catabolic process - - - 0.0000000000000000000000000000000000000007348 156.0
DTH2_k127_5633063_77 ribonuclease K01167 - 3.1.27.3 0.000000000000000000000000000000000000001837 151.0
DTH2_k127_5633063_78 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000005058 152.0
DTH2_k127_5633063_79 zinc-ribbon domain - - - 0.0000000000000000000000000000000000001032 156.0
DTH2_k127_5633063_8 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.493e-249 780.0
DTH2_k127_5633063_80 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000002651 153.0
DTH2_k127_5633063_81 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000004352 138.0
DTH2_k127_5633063_82 Lysin motif - - - 0.000000000000000000000000000000001811 140.0
DTH2_k127_5633063_83 KTSC domain - - - 0.000000000000000000000000000001052 121.0
DTH2_k127_5633063_84 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000001171 119.0
DTH2_k127_5633063_85 Barstar (barnase inhibitor) - - - 0.0000000000000000000003212 100.0
DTH2_k127_5633063_86 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000003545 98.0
DTH2_k127_5633063_87 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000001142 83.0
DTH2_k127_5633063_88 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.0000000000000005129 81.0
DTH2_k127_5633063_89 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000001309 72.0
DTH2_k127_5633063_9 RNB K01147 - 3.1.13.1 3.316e-219 698.0
DTH2_k127_5633063_91 - K06950 - - 0.000000002453 63.0
DTH2_k127_5633063_92 membrane K06077 - - 0.000000003551 61.0
DTH2_k127_5633063_93 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000001162 60.0
DTH2_k127_5633063_94 COG3133 Outer membrane lipoprotein K06077 - - 0.00000009256 58.0
DTH2_k127_5633063_95 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000001756 53.0
DTH2_k127_5633063_97 Protein of unknown function (DUF721) - - - 0.0005437 49.0
DTH2_k127_5704815_0 DNA polymerase K02337 - 2.7.7.7 0.0 1139.0
DTH2_k127_5704815_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0 1041.0
DTH2_k127_5704815_10 ribonuclease, Rne Rng family K08301 - - 1.403e-227 713.0
DTH2_k127_5704815_11 Bacterial extracellular solute-binding protein K10108 - - 1.327e-220 689.0
DTH2_k127_5704815_12 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 2.793e-216 687.0
DTH2_k127_5704815_13 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 1.533e-212 684.0
DTH2_k127_5704815_14 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.685e-207 651.0
DTH2_k127_5704815_15 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.239e-205 650.0
DTH2_k127_5704815_16 Belongs to the GARS family K01945 - 6.3.4.13 1.807e-202 640.0
DTH2_k127_5704815_17 PFAM extracellular solute-binding protein family 1 K17315 - - 7.155e-199 627.0
DTH2_k127_5704815_18 ABC transporter K10111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 574.0
DTH2_k127_5704815_19 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 576.0
DTH2_k127_5704815_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1038.0
DTH2_k127_5704815_20 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 564.0
DTH2_k127_5704815_21 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 571.0
DTH2_k127_5704815_22 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 560.0
DTH2_k127_5704815_23 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 546.0
DTH2_k127_5704815_24 Binding-protein-dependent transport system inner membrane component K10110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 527.0
DTH2_k127_5704815_25 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 504.0
DTH2_k127_5704815_26 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 509.0
DTH2_k127_5704815_27 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 509.0
DTH2_k127_5704815_28 ATPases associated with a variety of cellular activities K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 514.0
DTH2_k127_5704815_29 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 496.0
DTH2_k127_5704815_3 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 6.746e-314 968.0
DTH2_k127_5704815_30 Binding-protein-dependent transport system inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 478.0
DTH2_k127_5704815_31 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 482.0
DTH2_k127_5704815_32 TonB-dependent Receptor Plug Domain K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 446.0
DTH2_k127_5704815_33 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 433.0
DTH2_k127_5704815_34 Maltoporin (phage lambda and maltose receptor) K02024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 407.0
DTH2_k127_5704815_35 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 402.0
DTH2_k127_5704815_36 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 404.0
DTH2_k127_5704815_37 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 387.0
DTH2_k127_5704815_38 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 385.0
DTH2_k127_5704815_39 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 365.0
DTH2_k127_5704815_4 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 5.447e-296 929.0
DTH2_k127_5704815_40 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 357.0
DTH2_k127_5704815_41 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 343.0
DTH2_k127_5704815_42 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 322.0
DTH2_k127_5704815_43 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 321.0
DTH2_k127_5704815_44 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
DTH2_k127_5704815_45 cytochrome c biogenesis protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 304.0
DTH2_k127_5704815_46 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
DTH2_k127_5704815_47 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 284.0
DTH2_k127_5704815_48 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002493 259.0
DTH2_k127_5704815_49 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002971 242.0
DTH2_k127_5704815_5 Alpha amylase, catalytic domain K01176 - 3.2.1.1 3.914e-274 852.0
DTH2_k127_5704815_50 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000002367 232.0
DTH2_k127_5704815_51 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000003765 222.0
DTH2_k127_5704815_52 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000001857 220.0
DTH2_k127_5704815_53 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000002282 223.0
DTH2_k127_5704815_54 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000006767 214.0
DTH2_k127_5704815_55 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000007457 211.0
DTH2_k127_5704815_56 Bacterial pullanase-associated domain - - - 0.000000000000000000000000000000000000000000000000000000004331 204.0
DTH2_k127_5704815_57 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000003163 201.0
DTH2_k127_5704815_58 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000003739 210.0
DTH2_k127_5704815_59 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000001188 191.0
DTH2_k127_5704815_6 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.739e-270 848.0
DTH2_k127_5704815_60 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.00000000000000000000000000000000000000000000000000002484 196.0
DTH2_k127_5704815_61 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001705 186.0
DTH2_k127_5704815_62 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000008867 182.0
DTH2_k127_5704815_63 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000001959 180.0
DTH2_k127_5704815_64 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000005879 177.0
DTH2_k127_5704815_65 - - - - 0.00000000000000000000000000000000000000000000008941 175.0
DTH2_k127_5704815_66 - - - - 0.0000000000000000000000000000000000000000001496 168.0
DTH2_k127_5704815_67 - - - - 0.0000000000000000000000000000000000000000001626 172.0
DTH2_k127_5704815_68 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000004271 178.0
DTH2_k127_5704815_69 Histidine kinase - - - 0.000000000000000000000000000000005041 133.0
DTH2_k127_5704815_7 Bacterial protein of unknown function (DUF853) K06915 - - 9.283e-255 793.0
DTH2_k127_5704815_70 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000007444 134.0
DTH2_k127_5704815_71 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000106 136.0
DTH2_k127_5704815_72 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000003672 141.0
DTH2_k127_5704815_73 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000009126 133.0
DTH2_k127_5704815_74 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000001297 131.0
DTH2_k127_5704815_75 Tetratricopeptide repeat - - - 0.00000000000000000000000000000118 128.0
DTH2_k127_5704815_76 Cytochrome c K08738 - - 0.000000000000000000000000000005081 121.0
DTH2_k127_5704815_77 - - - - 0.000000000000000000000000007546 123.0
DTH2_k127_5704815_78 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001656 109.0
DTH2_k127_5704815_79 - - - - 0.0000000000000000000008952 109.0
DTH2_k127_5704815_8 Maltose transport system permease protein MalF P2 domain K10109 - - 8.556e-242 759.0
DTH2_k127_5704815_80 metal cluster binding - - - 0.0000000000000000000009446 102.0
DTH2_k127_5704815_81 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000005833 109.0
DTH2_k127_5704815_82 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000006489 108.0
DTH2_k127_5704815_83 redox protein, regulator of disulfide bond formation - - - 0.0000000000003389 81.0
DTH2_k127_5704815_84 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000118 59.0
DTH2_k127_5704815_85 Sel1 domain protein repeat-containing protein K07126 - - 0.0000002846 61.0
DTH2_k127_5704815_9 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835 - 5.4.2.2 4.84e-240 763.0
DTH2_k127_5775540_0 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000002268 202.0
DTH2_k127_5775540_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000002022 154.0
DTH2_k127_5775540_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000001775 61.0
DTH2_k127_5775540_2 nucleic acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000000000001868 148.0
DTH2_k127_5775540_3 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000006104 146.0
DTH2_k127_5775540_4 peptidase - - - 0.00000000000000000000000000000000006404 139.0
DTH2_k127_5775540_5 peptidase - - - 0.000000000000000000000000000002643 121.0
DTH2_k127_5775540_6 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000000001046 115.0
DTH2_k127_5775540_7 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000002686 109.0
DTH2_k127_5775540_8 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000000008865 102.0
DTH2_k127_5775540_9 positive regulation of growth - - - 0.00000000000000001217 84.0
DTH2_k127_5800999_0 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 1.002e-195 629.0
DTH2_k127_5800999_1 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 438.0
DTH2_k127_5800999_2 Helix-turn-helix XRE-family like proteins K07726 - - 0.00000000000000000000000000000000001079 138.0
DTH2_k127_5800999_3 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.000000000000000000000000000000001551 131.0
DTH2_k127_5970040_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
DTH2_k127_5970040_1 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 252.0
DTH2_k127_5970040_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000576 125.0
DTH2_k127_5987514_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 8.727e-267 823.0
DTH2_k127_5987514_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 468.0
DTH2_k127_5987514_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 439.0
DTH2_k127_5987514_3 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000000000009948 120.0
DTH2_k127_616317_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 8.926e-242 768.0
DTH2_k127_616317_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 468.0
DTH2_k127_616317_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 372.0
DTH2_k127_616317_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001381 278.0
DTH2_k127_616317_4 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000005748 225.0
DTH2_k127_616317_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000001365 197.0
DTH2_k127_616317_6 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000007736 98.0
DTH2_k127_6242689_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.051e-312 965.0
DTH2_k127_6242689_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.966e-218 695.0
DTH2_k127_6242689_10 - - - - 0.0000000000000000000000000000000005089 143.0
DTH2_k127_6242689_11 PFAM Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000003634 137.0
DTH2_k127_6242689_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 571.0
DTH2_k127_6242689_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 498.0
DTH2_k127_6242689_4 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
DTH2_k127_6242689_5 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 392.0
DTH2_k127_6242689_6 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 369.0
DTH2_k127_6242689_7 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000000001211 213.0
DTH2_k127_6242689_8 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000004042 188.0
DTH2_k127_6242689_9 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000283 179.0
DTH2_k127_6328447_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 509.0
DTH2_k127_6328447_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 490.0
DTH2_k127_6328447_10 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000005638 57.0
DTH2_k127_6328447_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009501 267.0
DTH2_k127_6328447_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000001471 240.0
DTH2_k127_6328447_5 PFAM NAD dependent epimerase dehydratase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000001276 207.0
DTH2_k127_6328447_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000003457 181.0
DTH2_k127_6328447_7 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000002958 181.0
DTH2_k127_6328447_8 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000001067 178.0
DTH2_k127_6328447_9 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000001021 122.0
DTH2_k127_6339016_0 Molecular chaperone. Has ATPase activity K04079 - - 2.375e-298 926.0
DTH2_k127_6339016_1 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 577.0
DTH2_k127_6339016_10 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
DTH2_k127_6339016_11 phosphorelay sensor kinase activity K02342,K02851 - 2.7.7.7,2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000005019 257.0
DTH2_k127_6339016_12 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000006471 251.0
DTH2_k127_6339016_13 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000005184 244.0
DTH2_k127_6339016_14 glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000004845 223.0
DTH2_k127_6339016_15 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000007057 202.0
DTH2_k127_6339016_16 Copper resistance protein D - - - 0.00000000000000000000000000000000005552 138.0
DTH2_k127_6339016_17 Cytochrome c - - - 0.00000000000000000000000000003538 121.0
DTH2_k127_6339016_18 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000001563 120.0
DTH2_k127_6339016_19 Cytochrome c, class I - - - 0.0000000000000000000000000002593 117.0
DTH2_k127_6339016_2 Transcriptional regulator with HTH domain and aminotransferase domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 511.0
DTH2_k127_6339016_20 Receptor family ligand binding region K01999 - - 0.0000000000099 72.0
DTH2_k127_6339016_21 Membrane protease subunits, stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001163 55.0
DTH2_k127_6339016_3 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 489.0
DTH2_k127_6339016_4 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 433.0
DTH2_k127_6339016_5 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 405.0
DTH2_k127_6339016_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 295.0
DTH2_k127_6339016_7 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000322 308.0
DTH2_k127_6339016_8 PFAM glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005539 279.0
DTH2_k127_6339016_9 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005417 271.0
DTH2_k127_634144_0 Aminotransferase class-III K00823 - 2.6.1.19 5.89e-217 683.0
DTH2_k127_634144_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.439e-201 631.0
DTH2_k127_634144_10 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 384.0
DTH2_k127_634144_11 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 362.0
DTH2_k127_634144_12 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 364.0
DTH2_k127_634144_13 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 364.0
DTH2_k127_634144_14 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 326.0
DTH2_k127_634144_15 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 297.0
DTH2_k127_634144_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009238 235.0
DTH2_k127_634144_17 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000001427 221.0
DTH2_k127_634144_18 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000007975 220.0
DTH2_k127_634144_19 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000001006 218.0
DTH2_k127_634144_2 TAP-like protein K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 547.0
DTH2_k127_634144_20 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000000000000000005671 173.0
DTH2_k127_634144_21 PFAM thiamineS protein - - - 0.000000000000000000000002801 104.0
DTH2_k127_634144_22 - - - - 0.000000000003674 70.0
DTH2_k127_634144_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 539.0
DTH2_k127_634144_4 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 505.0
DTH2_k127_634144_5 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 464.0
DTH2_k127_634144_6 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 448.0
DTH2_k127_634144_7 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 425.0
DTH2_k127_634144_8 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 404.0
DTH2_k127_634144_9 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 403.0
DTH2_k127_6439114_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0 1200.0
DTH2_k127_6439114_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1041.0
DTH2_k127_6439114_10 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101 - 1.1.2.3 2.488e-211 661.0
DTH2_k127_6439114_11 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 586.0
DTH2_k127_6439114_12 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 572.0
DTH2_k127_6439114_13 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 570.0
DTH2_k127_6439114_14 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 561.0
DTH2_k127_6439114_15 binding-protein-dependent transport systems inner membrane component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 476.0
DTH2_k127_6439114_16 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 473.0
DTH2_k127_6439114_17 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 447.0
DTH2_k127_6439114_18 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 435.0
DTH2_k127_6439114_19 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 433.0
DTH2_k127_6439114_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.737e-312 968.0
DTH2_k127_6439114_20 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 404.0
DTH2_k127_6439114_21 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 395.0
DTH2_k127_6439114_22 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
DTH2_k127_6439114_23 coenzyme F390 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 371.0
DTH2_k127_6439114_24 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 362.0
DTH2_k127_6439114_25 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 356.0
DTH2_k127_6439114_26 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 345.0
DTH2_k127_6439114_27 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
DTH2_k127_6439114_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 342.0
DTH2_k127_6439114_29 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 335.0
DTH2_k127_6439114_3 Phosphopantetheine attachment site - - - 3.917e-270 862.0
DTH2_k127_6439114_30 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 330.0
DTH2_k127_6439114_31 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 325.0
DTH2_k127_6439114_32 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 326.0
DTH2_k127_6439114_33 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 313.0
DTH2_k127_6439114_34 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
DTH2_k127_6439114_35 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005886 256.0
DTH2_k127_6439114_36 Prokaryotic cytochrome b561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
DTH2_k127_6439114_37 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
DTH2_k127_6439114_38 Electron transfer DM13 - - - 0.000000000000000000000000000000000000000000000000000000000000000003723 229.0
DTH2_k127_6439114_39 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
DTH2_k127_6439114_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.635e-269 837.0
DTH2_k127_6439114_40 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000136 222.0
DTH2_k127_6439114_41 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000003952 226.0
DTH2_k127_6439114_42 succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000004911 194.0
DTH2_k127_6439114_43 - - - - 0.000000000000000000000000000000000000000000002854 168.0
DTH2_k127_6439114_44 Nitroreductase family - - - 0.000000000000000000000000000000000000000000003303 171.0
DTH2_k127_6439114_45 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000001043 167.0
DTH2_k127_6439114_46 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000002671 152.0
DTH2_k127_6439114_47 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000000000000000135 143.0
DTH2_k127_6439114_48 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000001542 147.0
DTH2_k127_6439114_49 Transcriptional regulator K01420 - - 0.00000000000000000000000000000000000223 150.0
DTH2_k127_6439114_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 2.418e-244 769.0
DTH2_k127_6439114_50 Universal stress protein - - - 0.000000000000000000000000000000000003111 143.0
DTH2_k127_6439114_51 GYD domain - - - 0.0000000000000000000000000000000000258 138.0
DTH2_k127_6439114_52 nucleotidyltransferase activity - - - 0.000000000000000000000000000000001911 142.0
DTH2_k127_6439114_53 - - - - 0.0000000000000000000000000000001586 130.0
DTH2_k127_6439114_54 Protein of unknown function DUF86 - - - 0.000000000000000000000000000003371 123.0
DTH2_k127_6439114_55 Protein of unknown function (DUF504) - - - 0.00000000000000000000000003902 110.0
DTH2_k127_6439114_56 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000009877 108.0
DTH2_k127_6439114_57 - - - - 0.000000000000000000000005181 106.0
DTH2_k127_6439114_58 Protein of unknown function DUF86 - - - 0.00000000000000000000001684 106.0
DTH2_k127_6439114_59 - - - - 0.000000000000000000001276 97.0
DTH2_k127_6439114_6 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 2.528e-243 763.0
DTH2_k127_6439114_60 - - - - 0.00000000000000001165 83.0
DTH2_k127_6439114_61 Protein required for attachment to host cells - - - 0.0000000000000003276 84.0
DTH2_k127_6439114_63 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000004284 53.0
DTH2_k127_6439114_64 Transcriptional regulator - - - 0.0001273 45.0
DTH2_k127_6439114_7 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 1.718e-225 709.0
DTH2_k127_6439114_8 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 5.536e-216 679.0
DTH2_k127_6439114_9 protein containing a von Willebrand factor type A (vWA) domain - - - 8.537e-215 677.0
DTH2_k127_6523664_0 4Fe-4S dicluster domain - - - 0.0 1356.0
DTH2_k127_6523664_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1308.0
DTH2_k127_6523664_10 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 3.223e-204 641.0
DTH2_k127_6523664_11 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 559.0
DTH2_k127_6523664_12 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 534.0
DTH2_k127_6523664_13 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 515.0
DTH2_k127_6523664_14 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 512.0
DTH2_k127_6523664_15 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 486.0
DTH2_k127_6523664_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 471.0
DTH2_k127_6523664_17 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 452.0
DTH2_k127_6523664_18 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 421.0
DTH2_k127_6523664_19 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 407.0
DTH2_k127_6523664_2 CoA binding domain - - - 1.035e-296 925.0
DTH2_k127_6523664_20 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 401.0
DTH2_k127_6523664_21 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 365.0
DTH2_k127_6523664_22 4Fe-4S binding domain K18362 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 356.0
DTH2_k127_6523664_23 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 351.0
DTH2_k127_6523664_24 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 329.0
DTH2_k127_6523664_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
DTH2_k127_6523664_26 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
DTH2_k127_6523664_27 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003083 274.0
DTH2_k127_6523664_28 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
DTH2_k127_6523664_29 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
DTH2_k127_6523664_3 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 3.173e-247 782.0
DTH2_k127_6523664_30 lipase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007515 234.0
DTH2_k127_6523664_31 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000001601 229.0
DTH2_k127_6523664_32 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
DTH2_k127_6523664_33 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000102 215.0
DTH2_k127_6523664_34 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000000000000006818 198.0
DTH2_k127_6523664_35 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000004014 193.0
DTH2_k127_6523664_36 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000000000003116 186.0
DTH2_k127_6523664_37 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000003619 189.0
DTH2_k127_6523664_38 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000007637 183.0
DTH2_k127_6523664_39 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000001961 166.0
DTH2_k127_6523664_4 AMP-binding enzyme K12508 - 6.2.1.34 2.303e-246 774.0
DTH2_k127_6523664_40 transcriptional regulator - - - 0.000000000000000000000000000000000000414 144.0
DTH2_k127_6523664_41 N-acetyltransferase K00675 - 2.3.1.118 0.00000000000000000000000000000003666 137.0
DTH2_k127_6523664_42 PQ loop repeat K15383 - - 0.0000000000000000000000000003249 116.0
DTH2_k127_6523664_43 amine dehydrogenase activity K13730 - - 0.000000000000000000000000000705 127.0
DTH2_k127_6523664_44 - - - - 0.000000000000000000005699 104.0
DTH2_k127_6523664_45 PFAM CHRD domain containing protein - - - 0.00000000000000001038 91.0
DTH2_k127_6523664_46 Outer membrane protein beta-barrel domain - - - 0.0000000000000001415 88.0
DTH2_k127_6523664_5 GMC oxidoreductase K00108 - 1.1.99.1 8.165e-240 754.0
DTH2_k127_6523664_6 NHL repeat - - - 3.15e-226 706.0
DTH2_k127_6523664_7 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.346e-213 668.0
DTH2_k127_6523664_8 B12 binding domain - - - 1.249e-208 666.0
DTH2_k127_6523664_9 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 4.324e-207 651.0
DTH2_k127_6532217_0 Penicillin amidase K01434 - 3.5.1.11 3.472e-319 1002.0
DTH2_k127_6532217_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000001573 224.0
DTH2_k127_6532217_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000001839 122.0
DTH2_k127_6532217_3 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.00000000007501 74.0
DTH2_k127_656825_0 type VI secretion protein K11891 - - 0.0 1187.0
DTH2_k127_656825_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1105.0
DTH2_k127_656825_10 type VI secretion protein K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 475.0
DTH2_k127_656825_11 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 451.0
DTH2_k127_656825_12 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 453.0
DTH2_k127_656825_13 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 436.0
DTH2_k127_656825_14 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 425.0
DTH2_k127_656825_15 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 417.0
DTH2_k127_656825_16 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 404.0
DTH2_k127_656825_17 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 368.0
DTH2_k127_656825_18 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
DTH2_k127_656825_19 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 337.0
DTH2_k127_656825_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.353e-302 947.0
DTH2_k127_656825_20 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 314.0
DTH2_k127_656825_21 TIGRFAM type VI secretion system FHA domain protein K07169,K11913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 325.0
DTH2_k127_656825_22 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 294.0
DTH2_k127_656825_23 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000124 277.0
DTH2_k127_656825_24 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
DTH2_k127_656825_25 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 258.0
DTH2_k127_656825_26 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000001767 254.0
DTH2_k127_656825_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000939 242.0
DTH2_k127_656825_28 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000003122 226.0
DTH2_k127_656825_29 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000241 209.0
DTH2_k127_656825_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.207e-285 895.0
DTH2_k127_656825_30 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003707 194.0
DTH2_k127_656825_31 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000000001555 167.0
DTH2_k127_656825_32 - - - - 0.00000000000000000000000000000000000003909 149.0
DTH2_k127_656825_33 TIGRFAM type VI secretion lipoprotein, VC_A0113 family K11906 - - 0.000000000000000000000000000002412 130.0
DTH2_k127_656825_34 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000036 118.0
DTH2_k127_656825_35 Lysin motif - - - 0.0000000000000000000000001202 117.0
DTH2_k127_656825_36 Histidine kinase - - - 0.000000000000000000001141 109.0
DTH2_k127_656825_37 Antirepressor K07741 - - 0.0009869 49.0
DTH2_k127_656825_4 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.833e-259 807.0
DTH2_k127_656825_5 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 1.825e-215 678.0
DTH2_k127_656825_6 Extracellular solute-binding protein K02055,K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 597.0
DTH2_k127_656825_7 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 595.0
DTH2_k127_656825_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 552.0
DTH2_k127_656825_9 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 483.0
DTH2_k127_659948_0 ABC-type Fe3 transport system, permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 514.0
DTH2_k127_659948_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
DTH2_k127_659948_2 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 464.0
DTH2_k127_659948_3 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
DTH2_k127_659948_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000002023 123.0
DTH2_k127_659948_6 - - - - 0.0007114 47.0
DTH2_k127_6608630_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 5e-324 998.0
DTH2_k127_6608630_1 Transport of potassium into the cell K03549 - - 2.19e-229 726.0
DTH2_k127_6608630_10 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009172 242.0
DTH2_k127_6608630_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000003681 174.0
DTH2_k127_6608630_12 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.000000000000000000000000000001052 139.0
DTH2_k127_6608630_13 Thioredoxin domain - - - 0.0000000000000000004391 89.0
DTH2_k127_6608630_14 Predicted permease K07089 - - 0.000000000003264 72.0
DTH2_k127_6608630_2 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 1.666e-206 647.0
DTH2_k127_6608630_3 nucleoside-diphosphate sugar epimerase - - - 2.73e-200 634.0
DTH2_k127_6608630_4 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 458.0
DTH2_k127_6608630_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 475.0
DTH2_k127_6608630_6 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 435.0
DTH2_k127_6608630_7 Succinylglutamate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 339.0
DTH2_k127_6608630_8 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001139 280.0
DTH2_k127_6608630_9 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003218 280.0
DTH2_k127_6611071_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1482.0
DTH2_k127_6611071_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1007.0
DTH2_k127_6611071_10 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 463.0
DTH2_k127_6611071_11 DNA recombination protein, rmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 462.0
DTH2_k127_6611071_12 Elements of external origin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 447.0
DTH2_k127_6611071_13 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 414.0
DTH2_k127_6611071_14 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 365.0
DTH2_k127_6611071_15 major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 335.0
DTH2_k127_6611071_16 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
DTH2_k127_6611071_17 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002357 280.0
DTH2_k127_6611071_18 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009947 264.0
DTH2_k127_6611071_19 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006264 252.0
DTH2_k127_6611071_2 FtsX-like permease family K02004 - - 1.154e-278 880.0
DTH2_k127_6611071_20 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000008423 196.0
DTH2_k127_6611071_21 - - - - 0.00000000000000000000000000000000000000000002655 167.0
DTH2_k127_6611071_22 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000003308 160.0
DTH2_k127_6611071_23 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000005935 152.0
DTH2_k127_6611071_24 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000126 153.0
DTH2_k127_6611071_25 Tautomerase enzyme - - - 0.0000000000000000000000000000000000003113 146.0
DTH2_k127_6611071_26 Psort location Extracellular, score - - - 0.0000000000000000000000000221 118.0
DTH2_k127_6611071_27 protein conserved in bacteria K09966 - - 0.000000000000000000000001933 107.0
DTH2_k127_6611071_28 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000000000000127 109.0
DTH2_k127_6611071_29 Cysteine-rich secretory protein family - - - 0.00000000000000000000006293 106.0
DTH2_k127_6611071_3 Tripartite tricarboxylate transporter TctA family - - - 9.078e-253 788.0
DTH2_k127_6611071_30 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000003154 98.0
DTH2_k127_6611071_31 PIN domain - - - 0.0000000000000000000008544 102.0
DTH2_k127_6611071_32 MlaD protein K02067 - - 0.0000000000007996 79.0
DTH2_k127_6611071_33 PEP-CTERM motif - - - 0.000008864 48.0
DTH2_k127_6611071_34 protein related to plant photosystem II stability assembly factor - - - 0.0000107 55.0
DTH2_k127_6611071_35 3' exoribonuclease, RNase T-like - - - 0.00001452 58.0
DTH2_k127_6611071_37 - - - - 0.0005382 51.0
DTH2_k127_6611071_4 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.621e-246 767.0
DTH2_k127_6611071_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.613e-214 674.0
DTH2_k127_6611071_6 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 520.0
DTH2_k127_6611071_7 Aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 505.0
DTH2_k127_6611071_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 482.0
DTH2_k127_6611071_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 471.0
DTH2_k127_6619695_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000443 196.0
DTH2_k127_6619695_1 ribosome binding - - - 0.00006241 52.0
DTH2_k127_6623247_0 Domain of unknown function (DUF3362) - - - 0.0 1232.0
DTH2_k127_6623247_1 SNARE associated Golgi protein - - - 9.517e-317 985.0
DTH2_k127_6623247_10 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 543.0
DTH2_k127_6623247_100 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000004454 151.0
DTH2_k127_6623247_101 - - - - 0.0000000000000000000000000000000000001492 145.0
DTH2_k127_6623247_102 YHS domain protein - - - 0.000000000000000000000000000000000002567 145.0
DTH2_k127_6623247_103 SnoaL-like domain - - - 0.0000000000000000000000000000000001125 137.0
DTH2_k127_6623247_104 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000001516 139.0
DTH2_k127_6623247_105 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001698 136.0
DTH2_k127_6623247_106 - - - - 0.00000000000000000000000000000001861 132.0
DTH2_k127_6623247_107 GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001818 129.0
DTH2_k127_6623247_108 PIN domain - - - 0.0000000000000000000000000001502 121.0
DTH2_k127_6623247_109 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000006005 123.0
DTH2_k127_6623247_11 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 540.0
DTH2_k127_6623247_110 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000002131 116.0
DTH2_k127_6623247_111 Cold shock K03704 - - 0.000000000000000000000000009522 109.0
DTH2_k127_6623247_112 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000001645 111.0
DTH2_k127_6623247_113 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001383 102.0
DTH2_k127_6623247_114 Domain of unknown function (DUF1992) - - - 0.0000000000000000000009623 99.0
DTH2_k127_6623247_115 - - - - 0.000000000000000000001573 103.0
DTH2_k127_6623247_116 Hemerythrin HHE cation binding domain - - - 0.00000000000000001125 89.0
DTH2_k127_6623247_117 - - - - 0.0000000000000004873 79.0
DTH2_k127_6623247_118 Heavy-metal resistance - - - 0.00000000000000867 82.0
DTH2_k127_6623247_119 Cytochrome c - - - 0.0000000002899 61.0
DTH2_k127_6623247_12 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 539.0
DTH2_k127_6623247_120 positive regulation of growth - - - 0.00000008049 58.0
DTH2_k127_6623247_121 Cytochrome c - - - 0.0000004377 55.0
DTH2_k127_6623247_122 RsgA GTPase K06949 - 3.1.3.100 0.000001536 51.0
DTH2_k127_6623247_123 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000004384 54.0
DTH2_k127_6623247_124 Putative zinc-finger - - - 0.00001003 51.0
DTH2_k127_6623247_125 - - - - 0.00002471 48.0
DTH2_k127_6623247_13 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 527.0
DTH2_k127_6623247_14 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 511.0
DTH2_k127_6623247_15 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 507.0
DTH2_k127_6623247_16 Trypsin K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 493.0
DTH2_k127_6623247_17 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 467.0
DTH2_k127_6623247_18 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 462.0
DTH2_k127_6623247_19 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 461.0
DTH2_k127_6623247_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.691e-289 902.0
DTH2_k127_6623247_20 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 449.0
DTH2_k127_6623247_21 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 451.0
DTH2_k127_6623247_22 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 447.0
DTH2_k127_6623247_23 rieske 2fe-2s K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 425.0
DTH2_k127_6623247_24 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 420.0
DTH2_k127_6623247_25 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 419.0
DTH2_k127_6623247_26 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 413.0
DTH2_k127_6623247_27 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 412.0
DTH2_k127_6623247_28 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 407.0
DTH2_k127_6623247_29 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 402.0
DTH2_k127_6623247_3 peptidase M24 K01262 - 3.4.11.9 2.107e-258 810.0
DTH2_k127_6623247_30 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
DTH2_k127_6623247_31 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 393.0
DTH2_k127_6623247_32 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 388.0
DTH2_k127_6623247_33 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 388.0
DTH2_k127_6623247_34 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 377.0
DTH2_k127_6623247_35 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 388.0
DTH2_k127_6623247_36 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
DTH2_k127_6623247_37 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 374.0
DTH2_k127_6623247_38 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
DTH2_k127_6623247_39 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 357.0
DTH2_k127_6623247_4 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 2.052e-219 693.0
DTH2_k127_6623247_40 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
DTH2_k127_6623247_41 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 355.0
DTH2_k127_6623247_42 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 331.0
DTH2_k127_6623247_43 peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 331.0
DTH2_k127_6623247_44 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
DTH2_k127_6623247_45 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 346.0
DTH2_k127_6623247_46 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
DTH2_k127_6623247_47 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 321.0
DTH2_k127_6623247_48 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 318.0
DTH2_k127_6623247_49 SMART extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 312.0
DTH2_k127_6623247_5 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 2.367e-201 643.0
DTH2_k127_6623247_50 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 321.0
DTH2_k127_6623247_51 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 299.0
DTH2_k127_6623247_52 Two component transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
DTH2_k127_6623247_53 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 304.0
DTH2_k127_6623247_54 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
DTH2_k127_6623247_55 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 291.0
DTH2_k127_6623247_56 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 293.0
DTH2_k127_6623247_57 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 293.0
DTH2_k127_6623247_58 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
DTH2_k127_6623247_59 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003035 286.0
DTH2_k127_6623247_6 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 584.0
DTH2_k127_6623247_60 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002112 288.0
DTH2_k127_6623247_61 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004041 290.0
DTH2_k127_6623247_62 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
DTH2_k127_6623247_63 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003315 265.0
DTH2_k127_6623247_64 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004828 256.0
DTH2_k127_6623247_65 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002785 245.0
DTH2_k127_6623247_66 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000395 256.0
DTH2_k127_6623247_67 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001215 249.0
DTH2_k127_6623247_68 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000003794 249.0
DTH2_k127_6623247_69 Histidine kinase K07648 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005726 260.0
DTH2_k127_6623247_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 578.0
DTH2_k127_6623247_70 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
DTH2_k127_6623247_71 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.00000000000000000000000000000000000000000000000000000000000000000004851 240.0
DTH2_k127_6623247_72 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000005745 231.0
DTH2_k127_6623247_73 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000001209 237.0
DTH2_k127_6623247_74 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000001005 231.0
DTH2_k127_6623247_75 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000877 218.0
DTH2_k127_6623247_76 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001813 214.0
DTH2_k127_6623247_77 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000000000002237 218.0
DTH2_k127_6623247_78 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
DTH2_k127_6623247_79 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
DTH2_k127_6623247_8 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 563.0
DTH2_k127_6623247_80 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000001621 218.0
DTH2_k127_6623247_81 tetR family - - - 0.00000000000000000000000000000000000000000000000000000000001759 216.0
DTH2_k127_6623247_82 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001806 207.0
DTH2_k127_6623247_83 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000002504 210.0
DTH2_k127_6623247_84 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000372 197.0
DTH2_k127_6623247_85 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000001123 200.0
DTH2_k127_6623247_86 DNA-binding - - - 0.000000000000000000000000000000000000000000000000000003164 196.0
DTH2_k127_6623247_87 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000000004025 197.0
DTH2_k127_6623247_88 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000005524 196.0
DTH2_k127_6623247_89 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000002234 193.0
DTH2_k127_6623247_9 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 547.0
DTH2_k127_6623247_90 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000008594 194.0
DTH2_k127_6623247_91 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000001231 177.0
DTH2_k127_6623247_92 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000001371 179.0
DTH2_k127_6623247_93 Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000000000000117 171.0
DTH2_k127_6623247_94 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000004526 169.0
DTH2_k127_6623247_95 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000064 171.0
DTH2_k127_6623247_96 TPM domain - - - 0.00000000000000000000000000000000000000000001437 174.0
DTH2_k127_6623247_98 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000003216 157.0
DTH2_k127_6623247_99 - - - - 0.0000000000000000000000000000000000000006128 151.0
DTH2_k127_6630484_0 Histidine kinase K02487,K06596 - - 1.672e-307 990.0
DTH2_k127_6630484_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 521.0
DTH2_k127_6630484_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
DTH2_k127_6630484_3 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 365.0
DTH2_k127_6630484_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 317.0
DTH2_k127_6630484_5 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000004965 176.0
DTH2_k127_6630484_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000001345 170.0
DTH2_k127_6630484_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000006325 164.0
DTH2_k127_66871_0 FAD dependent oxidoreductase central domain - - - 0.0 1226.0
DTH2_k127_66871_1 Amidohydrolase family K01465 - 3.5.2.3 1.473e-203 641.0
DTH2_k127_66871_10 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000000000000000000000111 234.0
DTH2_k127_66871_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000007429 197.0
DTH2_k127_66871_12 Sarcosine oxidase, delta subunit family K22085 - 1.5.99.5 0.000000000000000000000000001465 117.0
DTH2_k127_66871_13 ABC transporter K02029,K10009 - - 0.0000000000000000000000009131 113.0
DTH2_k127_66871_2 Sarcosine oxidase, subunit beta K00303 - 1.5.3.1 3.674e-199 627.0
DTH2_k127_66871_3 PFAM ABC transporter related K02028,K09972,K10004 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 361.0
DTH2_k127_66871_4 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 342.0
DTH2_k127_66871_5 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 301.0
DTH2_k127_66871_6 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 299.0
DTH2_k127_66871_7 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000498 284.0
DTH2_k127_66871_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001865 276.0
DTH2_k127_66871_9 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001926 263.0
DTH2_k127_67768_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.494e-276 860.0
DTH2_k127_67768_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.56e-262 833.0
DTH2_k127_67768_10 succinylglutamate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 411.0
DTH2_k127_67768_11 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 411.0
DTH2_k127_67768_12 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
DTH2_k127_67768_13 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
DTH2_k127_67768_14 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 287.0
DTH2_k127_67768_15 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 281.0
DTH2_k127_67768_16 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006564 243.0
DTH2_k127_67768_17 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000002095 246.0
DTH2_k127_67768_18 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007666 228.0
DTH2_k127_67768_19 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
DTH2_k127_67768_2 protein related to plant photosystem II stability assembly factor - - - 4.632e-219 685.0
DTH2_k127_67768_20 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000154 140.0
DTH2_k127_67768_21 ThiS family K03636 - - 0.000000000000000000000000000000006969 128.0
DTH2_k127_67768_22 membrane K08972 - - 0.0000000000000000000000000000001311 129.0
DTH2_k127_67768_23 CoA binding domain - - - 0.0000000000000000000000000000009727 130.0
DTH2_k127_67768_24 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000005529 86.0
DTH2_k127_67768_25 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000002161 78.0
DTH2_k127_67768_26 - - - - 0.0000259 53.0
DTH2_k127_67768_3 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 587.0
DTH2_k127_67768_4 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 564.0
DTH2_k127_67768_5 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 526.0
DTH2_k127_67768_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 506.0
DTH2_k127_67768_7 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 492.0
DTH2_k127_67768_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 469.0
DTH2_k127_67768_9 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 438.0
DTH2_k127_6777732_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1277.0
DTH2_k127_6777732_1 aminopeptidase N K01256 - 3.4.11.2 5e-324 1013.0
DTH2_k127_6777732_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 427.0
DTH2_k127_6777732_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 372.0
DTH2_k127_6777732_12 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 335.0
DTH2_k127_6777732_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
DTH2_k127_6777732_14 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 339.0
DTH2_k127_6777732_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 319.0
DTH2_k127_6777732_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001673 291.0
DTH2_k127_6777732_17 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 270.0
DTH2_k127_6777732_18 dna polymerase iii K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000001955 260.0
DTH2_k127_6777732_19 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006825 247.0
DTH2_k127_6777732_2 Belongs to the peptidase M16 family K07263 - - 1.526e-318 1001.0
DTH2_k127_6777732_20 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000007448 248.0
DTH2_k127_6777732_21 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001485 250.0
DTH2_k127_6777732_22 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
DTH2_k127_6777732_23 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000283 229.0
DTH2_k127_6777732_24 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000001669 171.0
DTH2_k127_6777732_25 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000002477 171.0
DTH2_k127_6777732_26 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004623 169.0
DTH2_k127_6777732_27 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000000000000139 166.0
DTH2_k127_6777732_28 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000000000007459 155.0
DTH2_k127_6777732_29 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000001033 138.0
DTH2_k127_6777732_3 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 6.594e-275 863.0
DTH2_k127_6777732_30 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000003945 140.0
DTH2_k127_6777732_31 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000009947 63.0
DTH2_k127_6777732_32 Domain of unknown function (DUF4936) - - - 0.0000002636 56.0
DTH2_k127_6777732_4 acyl-CoA dehydrogenase K00248 - 1.3.8.1 6.818e-246 773.0
DTH2_k127_6777732_5 DEAD-like helicases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 598.0
DTH2_k127_6777732_6 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 498.0
DTH2_k127_6777732_7 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 498.0
DTH2_k127_6777732_8 viral genome integration into host DNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 428.0
DTH2_k127_6777732_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 399.0
DTH2_k127_6815442_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.356e-253 786.0
DTH2_k127_6815442_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 332.0
DTH2_k127_6815442_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000004296 163.0
DTH2_k127_6815442_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000008049 148.0
DTH2_k127_6815442_4 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000002313 142.0
DTH2_k127_6815442_5 mRNA binding - - - 0.000000000000000000000000007401 117.0
DTH2_k127_6815442_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000009349 110.0
DTH2_k127_6815442_7 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000001261 116.0
DTH2_k127_6825145_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1091.0
DTH2_k127_6825145_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1014.0
DTH2_k127_6825145_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.434e-256 792.0
DTH2_k127_6825145_11 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 2.104e-250 780.0
DTH2_k127_6825145_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.135e-247 766.0
DTH2_k127_6825145_13 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.221e-246 769.0
DTH2_k127_6825145_14 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.387e-241 749.0
DTH2_k127_6825145_15 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 4.054e-218 693.0
DTH2_k127_6825145_16 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 1.898e-207 657.0
DTH2_k127_6825145_17 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 1.868e-203 647.0
DTH2_k127_6825145_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 587.0
DTH2_k127_6825145_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 545.0
DTH2_k127_6825145_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 5e-324 1006.0
DTH2_k127_6825145_20 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 484.0
DTH2_k127_6825145_21 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 473.0
DTH2_k127_6825145_22 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 471.0
DTH2_k127_6825145_23 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 428.0
DTH2_k127_6825145_24 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 408.0
DTH2_k127_6825145_25 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 392.0
DTH2_k127_6825145_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 387.0
DTH2_k127_6825145_27 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 363.0
DTH2_k127_6825145_28 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 355.0
DTH2_k127_6825145_29 CoA-transferase activity K01027,K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 348.0
DTH2_k127_6825145_3 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 1.839e-315 971.0
DTH2_k127_6825145_30 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 352.0
DTH2_k127_6825145_31 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 352.0
DTH2_k127_6825145_32 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 340.0
DTH2_k127_6825145_33 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 336.0
DTH2_k127_6825145_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 325.0
DTH2_k127_6825145_36 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 334.0
DTH2_k127_6825145_37 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 334.0
DTH2_k127_6825145_38 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 311.0
DTH2_k127_6825145_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
DTH2_k127_6825145_4 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 9.703e-314 972.0
DTH2_k127_6825145_40 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 308.0
DTH2_k127_6825145_41 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 300.0
DTH2_k127_6825145_42 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 289.0
DTH2_k127_6825145_43 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001155 275.0
DTH2_k127_6825145_44 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001228 274.0
DTH2_k127_6825145_45 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
DTH2_k127_6825145_46 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
DTH2_k127_6825145_47 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
DTH2_k127_6825145_48 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.00000000000000000000000000000000000000000000000000000000000000000000093 239.0
DTH2_k127_6825145_49 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
DTH2_k127_6825145_5 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 9.132e-300 928.0
DTH2_k127_6825145_50 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000004646 235.0
DTH2_k127_6825145_51 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000007196 218.0
DTH2_k127_6825145_52 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001531 199.0
DTH2_k127_6825145_53 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000003134 206.0
DTH2_k127_6825145_54 tellurite resistance protein - - - 0.00000000000000000000000000000000000000000000000436 182.0
DTH2_k127_6825145_55 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000001094 160.0
DTH2_k127_6825145_56 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000001642 152.0
DTH2_k127_6825145_57 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000003237 151.0
DTH2_k127_6825145_58 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000005539 146.0
DTH2_k127_6825145_59 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000006979 133.0
DTH2_k127_6825145_6 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.399e-279 869.0
DTH2_k127_6825145_60 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000008123 128.0
DTH2_k127_6825145_61 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000001004 118.0
DTH2_k127_6825145_62 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000004275 108.0
DTH2_k127_6825145_63 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000001903 107.0
DTH2_k127_6825145_64 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000004477 78.0
DTH2_k127_6825145_65 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000101 74.0
DTH2_k127_6825145_67 - - - - 0.000000000181 70.0
DTH2_k127_6825145_68 Protein of unknown function (DUF3024) - - - 0.0000006001 55.0
DTH2_k127_6825145_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.249e-267 828.0
DTH2_k127_6825145_8 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.253e-266 826.0
DTH2_k127_6825145_9 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.376e-265 829.0
DTH2_k127_6826429_0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000008757 228.0
DTH2_k127_6826429_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000001616 179.0
DTH2_k127_6826429_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000005655 169.0
DTH2_k127_7221879_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1135.0
DTH2_k127_7221879_1 Acyl-CoA dehydrogenase N terminal - - - 7.647e-272 852.0
DTH2_k127_7221879_10 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 308.0
DTH2_k127_7221879_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004697 280.0
DTH2_k127_7221879_12 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002946 285.0
DTH2_k127_7221879_13 PFAM Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001117 271.0
DTH2_k127_7221879_14 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000001612 241.0
DTH2_k127_7221879_15 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
DTH2_k127_7221879_16 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000004535 213.0
DTH2_k127_7221879_17 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000001458 210.0
DTH2_k127_7221879_18 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000003223 211.0
DTH2_k127_7221879_19 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000002787 202.0
DTH2_k127_7221879_2 Acyl-CoA synthetase (NDP forming) K09181 - - 1.399e-259 829.0
DTH2_k127_7221879_20 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000001067 174.0
DTH2_k127_7221879_21 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000001063 169.0
DTH2_k127_7221879_22 TraB family K09973 - - 0.00000000000000000000000000000000000000000003565 172.0
DTH2_k127_7221879_23 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000001055 160.0
DTH2_k127_7221879_24 hydrogenase maturation protease - - - 0.00000000000000000000000000000000000409 142.0
DTH2_k127_7221879_26 assembly chaperone K07346 - - 0.0000000000000000000000008769 114.0
DTH2_k127_7221879_27 dksA traR - - - 0.0000000000000000001554 93.0
DTH2_k127_7221879_28 Spore Coat Protein U domain - - - 0.0000000000000000001931 94.0
DTH2_k127_7221879_29 Secreted protein - - - 0.000000000000000006671 90.0
DTH2_k127_7221879_3 CHAT domain - - - 1.798e-256 821.0
DTH2_k127_7221879_30 Spore Coat Protein U domain - - - 0.00000000000001117 81.0
DTH2_k127_7221879_31 PFAM Glycosyl transferases group 1 K12995 - 2.4.1.348 0.00000000000132 76.0
DTH2_k127_7221879_4 Belongs to the thiolase family K00632 - 2.3.1.16 7.108e-202 634.0
DTH2_k127_7221879_5 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 572.0
DTH2_k127_7221879_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 444.0
DTH2_k127_7221879_7 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 408.0
DTH2_k127_7221879_8 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 383.0
DTH2_k127_7221879_9 Outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 364.0
DTH2_k127_737895_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1055.0
DTH2_k127_737895_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.074e-284 886.0
DTH2_k127_737895_10 transcriptional regulator, Rrf2 family K13643 - - 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
DTH2_k127_737895_11 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000004367 191.0
DTH2_k127_737895_12 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000006041 176.0
DTH2_k127_737895_13 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000002585 174.0
DTH2_k127_737895_14 NUDIX domain - - - 0.000000000000000000000000000000000000000000004849 177.0
DTH2_k127_737895_15 nitrogen regulatory protein P-II - - - 0.000000000000000000000000000004874 135.0
DTH2_k127_737895_16 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000009198 112.0
DTH2_k127_737895_17 - - - - 0.000000000000000000001403 96.0
DTH2_k127_737895_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 3.486e-233 732.0
DTH2_k127_737895_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.612e-227 706.0
DTH2_k127_737895_4 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 593.0
DTH2_k127_737895_5 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 374.0
DTH2_k127_737895_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 260.0
DTH2_k127_737895_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005466 256.0
DTH2_k127_737895_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009227 244.0
DTH2_k127_737895_9 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002143 237.0
DTH2_k127_7391074_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1299.0
DTH2_k127_7391074_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1262.0
DTH2_k127_7391074_10 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 571.0
DTH2_k127_7391074_11 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 512.0
DTH2_k127_7391074_12 sulfide dehydrogenase K05301 - 1.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 510.0
DTH2_k127_7391074_13 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 506.0
DTH2_k127_7391074_14 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 481.0
DTH2_k127_7391074_15 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 405.0
DTH2_k127_7391074_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 411.0
DTH2_k127_7391074_17 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 - 1.1.1.178,1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 375.0
DTH2_k127_7391074_18 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 381.0
DTH2_k127_7391074_19 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 362.0
DTH2_k127_7391074_2 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1016.0
DTH2_k127_7391074_20 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 346.0
DTH2_k127_7391074_21 mechanosensitive K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 348.0
DTH2_k127_7391074_22 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 333.0
DTH2_k127_7391074_23 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 317.0
DTH2_k127_7391074_24 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 309.0
DTH2_k127_7391074_25 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 305.0
DTH2_k127_7391074_26 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002418 267.0
DTH2_k127_7391074_27 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003712 286.0
DTH2_k127_7391074_28 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001689 247.0
DTH2_k127_7391074_29 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000001232 243.0
DTH2_k127_7391074_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 5.032e-315 979.0
DTH2_k127_7391074_30 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000003889 237.0
DTH2_k127_7391074_31 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000001038 224.0
DTH2_k127_7391074_32 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000001932 223.0
DTH2_k127_7391074_33 N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000003564 213.0
DTH2_k127_7391074_34 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000526 224.0
DTH2_k127_7391074_35 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000001439 191.0
DTH2_k127_7391074_36 - - - - 0.0000000000000000000000000000000000000000000000001215 181.0
DTH2_k127_7391074_37 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000007397 166.0
DTH2_k127_7391074_38 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000005317 168.0
DTH2_k127_7391074_39 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000001395 157.0
DTH2_k127_7391074_4 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 2.575e-308 957.0
DTH2_k127_7391074_40 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000016 147.0
DTH2_k127_7391074_41 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000000000000001925 143.0
DTH2_k127_7391074_42 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001664 138.0
DTH2_k127_7391074_43 Cold shock protein K03704 - - 0.0000000000000000000000000000000002042 134.0
DTH2_k127_7391074_44 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000002851 108.0
DTH2_k127_7391074_45 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000005178 119.0
DTH2_k127_7391074_46 Trm112p-like protein K09791 - - 0.00000000000000000000006548 99.0
DTH2_k127_7391074_47 cytochrome - - - 0.000000000000000000002817 98.0
DTH2_k127_7391074_48 toxin-antitoxin pair type II binding - - - 0.000000000000000126 82.0
DTH2_k127_7391074_49 trans-aconitate 2-methyltransferase activity K00563,K02169,K16868 - 2.1.1.187,2.1.1.197,2.1.1.265 0.0000000000000003179 89.0
DTH2_k127_7391074_5 Converts isocitrate to alpha ketoglutarate K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 5.822e-239 743.0
DTH2_k127_7391074_50 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.00000000003788 67.0
DTH2_k127_7391074_51 - - - - 0.0002086 51.0
DTH2_k127_7391074_6 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.693e-224 700.0
DTH2_k127_7391074_7 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 7.494e-222 700.0
DTH2_k127_7391074_8 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.461e-215 684.0
DTH2_k127_7391074_9 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.104e-212 672.0
DTH2_k127_7588838_0 AcrB/AcrD/AcrF family - - - 0.0 1355.0
DTH2_k127_7588838_1 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.026e-270 846.0
DTH2_k127_7588838_10 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000004475 110.0
DTH2_k127_7588838_11 Protein of unknown function (DUF2846) - - - 0.000000000000000000005589 99.0
DTH2_k127_7588838_12 - - - - 0.00000000000000002986 85.0
DTH2_k127_7588838_13 Metal-sensitive transcriptional repressor - - - 0.00000000000002406 76.0
DTH2_k127_7588838_2 Protein of unknown function (DUF1298) - - - 2.126e-236 743.0
DTH2_k127_7588838_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 454.0
DTH2_k127_7588838_4 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 391.0
DTH2_k127_7588838_5 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 337.0
DTH2_k127_7588838_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003569 242.0
DTH2_k127_7588838_7 CHAD - - - 0.000000000000000000000000000000000000000000000000000000000000008599 235.0
DTH2_k127_7588838_8 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000000001293 216.0
DTH2_k127_7588838_9 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000008199 191.0
DTH2_k127_7625619_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1014.0
DTH2_k127_7625619_1 DNA helicase K03657 - 3.6.4.12 8.901e-295 919.0
DTH2_k127_7625619_10 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 290.0
DTH2_k127_7625619_11 HIUase/Transthyretin family K07127 - 3.5.2.17 0.000000000000000000000000000005114 124.0
DTH2_k127_7625619_12 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.00000000000000000000000000003117 118.0
DTH2_k127_7625619_13 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000009019 107.0
DTH2_k127_7625619_14 - - - - 0.00000000000000000001075 100.0
DTH2_k127_7625619_15 Transposase IS200 like K07491 - - 0.00000000000000000002993 91.0
DTH2_k127_7625619_16 Transposase IS200 like K07491 - - 0.00000000000000000007601 89.0
DTH2_k127_7625619_17 Transposase IS200 like K07491 - - 0.00000000000000000019 93.0
DTH2_k127_7625619_18 - - - - 0.000000000000121 76.0
DTH2_k127_7625619_19 DNA integration - - - 0.0000001815 53.0
DTH2_k127_7625619_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 1.686e-223 701.0
DTH2_k127_7625619_3 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 601.0
DTH2_k127_7625619_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 475.0
DTH2_k127_7625619_5 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 475.0
DTH2_k127_7625619_6 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 398.0
DTH2_k127_7625619_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 384.0
DTH2_k127_7625619_8 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 365.0
DTH2_k127_7625619_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
DTH2_k127_7663426_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 577.0
DTH2_k127_7663426_1 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 440.0
DTH2_k127_7663426_10 - - - - 0.000000000000001506 82.0
DTH2_k127_7663426_11 - - - - 0.00000004088 55.0
DTH2_k127_7663426_2 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 430.0
DTH2_k127_7663426_3 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 382.0
DTH2_k127_7663426_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 284.0
DTH2_k127_7663426_5 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 290.0
DTH2_k127_7663426_6 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001171 293.0
DTH2_k127_7663426_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000001179 172.0
DTH2_k127_7663426_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000001649 151.0
DTH2_k127_7663426_9 - - - - 0.00000000000000006444 85.0
DTH2_k127_7690621_0 Glycosyl transferases group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 428.0
DTH2_k127_7690621_1 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 338.0
DTH2_k127_7739623_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.476e-265 829.0
DTH2_k127_7739623_1 Glycolate oxidase subunit GlcD K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 2.232e-230 730.0
DTH2_k127_7739623_10 FAD binding K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 442.0
DTH2_k127_7739623_11 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
DTH2_k127_7739623_12 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 293.0
DTH2_k127_7739623_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 302.0
DTH2_k127_7739623_14 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004897 279.0
DTH2_k127_7739623_15 response regulator K15012 - - 0.000000000000000000000000000000000000000000000000000000000002571 214.0
DTH2_k127_7739623_16 Signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000003623 201.0
DTH2_k127_7739623_17 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000002915 182.0
DTH2_k127_7739623_18 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000009615 153.0
DTH2_k127_7739623_19 COG1226 Kef-type K transport systems - - - 0.0000000000000000000000000000000000001615 146.0
DTH2_k127_7739623_2 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 8.884e-224 702.0
DTH2_k127_7739623_20 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000001679 133.0
DTH2_k127_7739623_21 - - - - 0.00000000000000000001154 101.0
DTH2_k127_7739623_22 Dodecin K09165 - - 0.000000000000000000216 91.0
DTH2_k127_7739623_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.535e-223 711.0
DTH2_k127_7739623_4 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 604.0
DTH2_k127_7739623_5 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 581.0
DTH2_k127_7739623_6 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 584.0
DTH2_k127_7739623_7 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 522.0
DTH2_k127_7739623_8 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 509.0
DTH2_k127_7739623_9 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 448.0
DTH2_k127_775696_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1709.0
DTH2_k127_775696_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1004.0
DTH2_k127_775696_10 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 483.0
DTH2_k127_775696_11 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 480.0
DTH2_k127_775696_12 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 457.0
DTH2_k127_775696_13 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 440.0
DTH2_k127_775696_14 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 411.0
DTH2_k127_775696_15 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 372.0
DTH2_k127_775696_16 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 322.0
DTH2_k127_775696_17 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 287.0
DTH2_k127_775696_18 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006153 288.0
DTH2_k127_775696_19 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
DTH2_k127_775696_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 6.942e-199 635.0
DTH2_k127_775696_20 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000128 246.0
DTH2_k127_775696_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 232.0
DTH2_k127_775696_22 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001104 222.0
DTH2_k127_775696_23 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000005136 206.0
DTH2_k127_775696_24 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000117 202.0
DTH2_k127_775696_25 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000003904 183.0
DTH2_k127_775696_26 MAPEG family - - - 0.00000000000000000000000000000000002661 139.0
DTH2_k127_775696_27 CRS1_YhbY K07574 - - 0.00000000000000000000000000000001751 130.0
DTH2_k127_775696_28 competence protein - - - 0.0000000000000000000000000000002756 138.0
DTH2_k127_775696_29 PFAM EAL domain - - - 0.000000000000000000000000000329 131.0
DTH2_k127_775696_3 CoA-transferase family III K07749 - 2.8.3.16 2.956e-198 632.0
DTH2_k127_775696_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.321e-195 619.0
DTH2_k127_775696_5 binding-protein-dependent transport systems inner membrane component K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 605.0
DTH2_k127_775696_6 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 578.0
DTH2_k127_775696_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 580.0
DTH2_k127_775696_8 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 504.0
DTH2_k127_775696_9 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 504.0
DTH2_k127_7803033_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 606.0
DTH2_k127_7803033_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 562.0
DTH2_k127_7803033_10 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
DTH2_k127_7803033_11 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
DTH2_k127_7803033_12 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
DTH2_k127_7803033_13 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000001578 214.0
DTH2_k127_7803033_14 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000008887 208.0
DTH2_k127_7803033_15 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000006765 202.0
DTH2_k127_7803033_16 Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000002899 197.0
DTH2_k127_7803033_17 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000009837 187.0
DTH2_k127_7803033_18 - - - - 0.00000000000000000000000000000000000000000000000000139 195.0
DTH2_k127_7803033_19 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000004673 183.0
DTH2_k127_7803033_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 483.0
DTH2_k127_7803033_20 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000225 139.0
DTH2_k127_7803033_21 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000001054 121.0
DTH2_k127_7803033_22 Hsp20/alpha crystallin family - - - 0.0000000000000000000000001346 111.0
DTH2_k127_7803033_23 CAAX protease self-immunity K07052 - - 0.0000000000000000000001298 106.0
DTH2_k127_7803033_24 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000172 94.0
DTH2_k127_7803033_25 Prokaryotic cytochrome b561 K12262 - - 0.0006089 44.0
DTH2_k127_7803033_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 475.0
DTH2_k127_7803033_4 NADH:flavin oxidoreductase / NADH oxidase family K00354,K09461 - 1.14.13.40,1.6.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 466.0
DTH2_k127_7803033_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 399.0
DTH2_k127_7803033_6 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 340.0
DTH2_k127_7803033_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 304.0
DTH2_k127_7803033_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006219 254.0
DTH2_k127_7803033_9 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000006104 253.0
DTH2_k127_7836980_0 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 324.0
DTH2_k127_7836980_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000004089 198.0
DTH2_k127_7836980_2 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000168 181.0
DTH2_k127_7836980_3 Protease prsW family - - - 0.000000000000000000000000000000000000005842 158.0
DTH2_k127_7850847_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 302.0
DTH2_k127_7850847_1 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009915 272.0
DTH2_k127_7850847_2 Plasmid stabilization system K19092 - - 0.00000000000000000000000000005096 119.0
DTH2_k127_7850847_3 Ribbon-helix-helix protein, copG family - - - 0.0000000000000000007824 88.0
DTH2_k127_7850847_4 Fatty acid hydroxylase superfamily - - - 0.000000000562 63.0
DTH2_k127_7850847_5 Methyltransferase domain - - - 0.00000886 48.0
DTH2_k127_7850847_6 Phage integrase family - - - 0.00002662 48.0
DTH2_k127_7889137_0 SurA N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 303.0
DTH2_k127_7889137_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001041 286.0
DTH2_k127_7889137_2 - - - - 0.00000000000000000000005292 109.0
DTH2_k127_7904579_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 6.182e-215 681.0
DTH2_k127_7904579_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 1.084e-202 645.0
DTH2_k127_7904579_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 300.0
DTH2_k127_7904579_11 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 290.0
DTH2_k127_7904579_12 amino acid ABC transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
DTH2_k127_7904579_13 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003427 267.0
DTH2_k127_7904579_14 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005835 252.0
DTH2_k127_7904579_15 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000001389 181.0
DTH2_k127_7904579_16 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000003732 145.0
DTH2_k127_7904579_17 Aspartyl protease K06985 - - 0.00000000000000003952 93.0
DTH2_k127_7904579_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 612.0
DTH2_k127_7904579_3 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 569.0
DTH2_k127_7904579_4 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 416.0
DTH2_k127_7904579_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 426.0
DTH2_k127_7904579_6 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 398.0
DTH2_k127_7904579_7 PFAM sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 400.0
DTH2_k127_7904579_8 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 378.0
DTH2_k127_7904579_9 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 339.0
DTH2_k127_793523_0 Proton-conducting membrane transporter - - - 1.287e-306 951.0
DTH2_k127_793523_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.673e-300 936.0
DTH2_k127_793523_10 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 341.0
DTH2_k127_793523_11 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 325.0
DTH2_k127_793523_12 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 317.0
DTH2_k127_793523_13 Transcriptional regulator K04033 - - 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
DTH2_k127_793523_14 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000006854 171.0
DTH2_k127_793523_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000002712 149.0
DTH2_k127_793523_16 COG3209 Rhs family protein - - - 0.00000000000000000000000000002467 131.0
DTH2_k127_793523_17 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000001615 98.0
DTH2_k127_793523_18 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000002012 101.0
DTH2_k127_793523_19 - - - - 0.0000000000000000000519 98.0
DTH2_k127_793523_2 Proton-conducting membrane transporter K12141 - - 1.509e-244 779.0
DTH2_k127_793523_20 Domain of unknown function (DUF1330) - - - 0.00000000006321 67.0
DTH2_k127_793523_21 aspartyl asparaginyl K12979 - - 0.0001516 48.0
DTH2_k127_793523_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 4.652e-196 622.0
DTH2_k127_793523_4 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 598.0
DTH2_k127_793523_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 591.0
DTH2_k127_793523_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 538.0
DTH2_k127_793523_7 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 476.0
DTH2_k127_793523_8 Histidine kinase K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 459.0
DTH2_k127_793523_9 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
DTH2_k127_8014250_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1187.0
DTH2_k127_8014250_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 404.0
DTH2_k127_8067445_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 484.0
DTH2_k127_8067445_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 338.0
DTH2_k127_8113543_0 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 407.0
DTH2_k127_8113543_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000002976 220.0
DTH2_k127_8113543_2 Glycosyltransferase like family 2 - - - 0.00000000000000004175 96.0
DTH2_k127_8250662_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1176.0
DTH2_k127_8250662_1 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 523.0
DTH2_k127_8250662_2 surface antigen (D15) K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 427.0
DTH2_k127_8250662_3 GGDEF domain - - - 0.0002626 45.0
DTH2_k127_8258309_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.021e-228 730.0
DTH2_k127_8258309_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.393e-219 690.0
DTH2_k127_8258309_10 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 456.0
DTH2_k127_8258309_11 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 440.0
DTH2_k127_8258309_12 Mg2 and Co2 transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
DTH2_k127_8258309_13 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 370.0
DTH2_k127_8258309_14 response regulator K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 352.0
DTH2_k127_8258309_15 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 290.0
DTH2_k127_8258309_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
DTH2_k127_8258309_17 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002132 262.0
DTH2_k127_8258309_18 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000241 260.0
DTH2_k127_8258309_19 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000007372 239.0
DTH2_k127_8258309_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.143e-199 627.0
DTH2_k127_8258309_20 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
DTH2_k127_8258309_21 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
DTH2_k127_8258309_22 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000001474 212.0
DTH2_k127_8258309_23 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000003735 214.0
DTH2_k127_8258309_24 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000002313 160.0
DTH2_k127_8258309_25 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000004722 136.0
DTH2_k127_8258309_26 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000005235 86.0
DTH2_k127_8258309_27 - - - - 0.00000000000001405 77.0
DTH2_k127_8258309_28 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000004056 73.0
DTH2_k127_8258309_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 617.0
DTH2_k127_8258309_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 581.0
DTH2_k127_8258309_5 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 536.0
DTH2_k127_8258309_6 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 543.0
DTH2_k127_8258309_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 509.0
DTH2_k127_8258309_8 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 461.0
DTH2_k127_8258309_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 468.0
DTH2_k127_8324045_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 538.0
DTH2_k127_83254_0 Mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 486.0
DTH2_k127_83254_1 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000006408 196.0
DTH2_k127_832572_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1553.0
DTH2_k127_832572_1 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1196.0
DTH2_k127_832572_10 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 582.0
DTH2_k127_832572_11 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 559.0
DTH2_k127_832572_12 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 554.0
DTH2_k127_832572_13 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 532.0
DTH2_k127_832572_14 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 516.0
DTH2_k127_832572_15 D-aminoacylase domain protein K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 518.0
DTH2_k127_832572_16 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 503.0
DTH2_k127_832572_17 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 499.0
DTH2_k127_832572_18 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 492.0
DTH2_k127_832572_19 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 488.0
DTH2_k127_832572_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 1.346e-293 910.0
DTH2_k127_832572_20 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 494.0
DTH2_k127_832572_21 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 490.0
DTH2_k127_832572_22 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 458.0
DTH2_k127_832572_23 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 460.0
DTH2_k127_832572_24 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 446.0
DTH2_k127_832572_25 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 447.0
DTH2_k127_832572_26 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 445.0
DTH2_k127_832572_27 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 453.0
DTH2_k127_832572_28 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 426.0
DTH2_k127_832572_29 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 419.0
DTH2_k127_832572_3 Belongs to the peptidase S16 family - - - 3.813e-280 882.0
DTH2_k127_832572_30 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 420.0
DTH2_k127_832572_31 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 411.0
DTH2_k127_832572_32 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 384.0
DTH2_k127_832572_33 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 329.0
DTH2_k127_832572_34 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 312.0
DTH2_k127_832572_35 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 268.0
DTH2_k127_832572_36 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 256.0
DTH2_k127_832572_37 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000006697 243.0
DTH2_k127_832572_38 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000545 213.0
DTH2_k127_832572_39 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000002432 184.0
DTH2_k127_832572_4 cysteine protease - - - 4.941e-234 743.0
DTH2_k127_832572_40 peptidyl-tyrosine sulfation - - - 0.00000000000000000000001233 110.0
DTH2_k127_832572_41 abc transporter atp-binding protein K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 0.000000000000000001546 85.0
DTH2_k127_832572_42 Belongs to the ParB family K03497 - - 0.00000000000002281 79.0
DTH2_k127_832572_43 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000001432 73.0
DTH2_k127_832572_44 AMP binding - - - 0.000105 52.0
DTH2_k127_832572_5 L-serine dehydratase K01752 - 4.3.1.17 1.855e-228 719.0
DTH2_k127_832572_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.321e-222 704.0
DTH2_k127_832572_7 ABC-type dipeptide transport system periplasmic component K02035 - - 1.88e-217 690.0
DTH2_k127_832572_8 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 592.0
DTH2_k127_832572_9 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 583.0
DTH2_k127_83312_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.881e-209 670.0
DTH2_k127_83312_1 Poly-beta-hydroxybutyrate polymerase K03821 - - 1.922e-207 664.0
DTH2_k127_83312_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 366.0
DTH2_k127_83312_11 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
DTH2_k127_83312_12 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 349.0
DTH2_k127_83312_13 glutathione transferase activity K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 297.0
DTH2_k127_83312_14 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 293.0
DTH2_k127_83312_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14583,K14751 - 1.13.11.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 292.0
DTH2_k127_83312_16 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009492 279.0
DTH2_k127_83312_17 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
DTH2_k127_83312_18 Tryptophan-rich sensory protein K05770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 266.0
DTH2_k127_83312_19 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001421 260.0
DTH2_k127_83312_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 549.0
DTH2_k127_83312_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000001106 220.0
DTH2_k127_83312_21 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000004975 212.0
DTH2_k127_83312_22 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000003944 200.0
DTH2_k127_83312_23 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000002106 190.0
DTH2_k127_83312_24 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000174 181.0
DTH2_k127_83312_25 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001953 169.0
DTH2_k127_83312_26 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000006119 167.0
DTH2_k127_83312_27 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002927 166.0
DTH2_k127_83312_28 - - - - 0.000000000000000000000000000000000000000009088 165.0
DTH2_k127_83312_29 - - - - 0.00000000000000000000000000000000000000002137 165.0
DTH2_k127_83312_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 534.0
DTH2_k127_83312_30 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000001278 155.0
DTH2_k127_83312_31 acetyltransferase - - - 0.000000000000000000000000000000000001748 144.0
DTH2_k127_83312_32 Rubrerythrin - - - 0.00000000000000000000000000000000002938 147.0
DTH2_k127_83312_33 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000059 138.0
DTH2_k127_83312_34 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000001075 140.0
DTH2_k127_83312_35 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000002103 138.0
DTH2_k127_83312_36 PFAM glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000002584 119.0
DTH2_k127_83312_37 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000002559 108.0
DTH2_k127_83312_38 SnoaL-like domain - - - 0.00000000000000000009281 95.0
DTH2_k127_83312_39 DUF167 K09131 - - 0.00000000000000000009413 91.0
DTH2_k127_83312_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 537.0
DTH2_k127_83312_40 Phosphotransferase System K11189 - - 0.0000000000000001028 84.0
DTH2_k127_83312_41 SnoaL-like domain - - - 0.000000002465 63.0
DTH2_k127_83312_42 SnoaL-like domain - - - 0.00000002788 62.0
DTH2_k127_83312_43 SnoaL-like polyketide cyclase - - - 0.00000007044 56.0
DTH2_k127_83312_44 MacB-like periplasmic core domain K02004 - - 0.0001224 52.0
DTH2_k127_83312_45 - - - - 0.0003345 45.0
DTH2_k127_83312_46 Protein of unknown function (DUF2934) - - - 0.0003671 48.0
DTH2_k127_83312_5 Lanthionine synthetase C-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 516.0
DTH2_k127_83312_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 460.0
DTH2_k127_83312_7 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 446.0
DTH2_k127_83312_8 Carbon-nitrogen hydrolase K01501,K01502 GO:0000257,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016815,GO:0018762,GO:0022607,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0065003,GO:0071840 3.5.5.1,3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 431.0
DTH2_k127_83312_9 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 404.0
DTH2_k127_8337300_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1632.0
DTH2_k127_8337300_1 helicase superfamily c-terminal domain K03724 - - 0.0 1071.0
DTH2_k127_8337300_10 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 496.0
DTH2_k127_8337300_11 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 445.0
DTH2_k127_8337300_12 PhoD-like phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 449.0
DTH2_k127_8337300_13 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 437.0
DTH2_k127_8337300_14 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 418.0
DTH2_k127_8337300_15 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 409.0
DTH2_k127_8337300_16 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 406.0
DTH2_k127_8337300_17 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 382.0
DTH2_k127_8337300_18 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
DTH2_k127_8337300_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 301.0
DTH2_k127_8337300_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.45e-322 992.0
DTH2_k127_8337300_20 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
DTH2_k127_8337300_21 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000004747 195.0
DTH2_k127_8337300_22 Nudix hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000004969 188.0
DTH2_k127_8337300_23 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000002686 183.0
DTH2_k127_8337300_24 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000007439 174.0
DTH2_k127_8337300_25 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000000002381 165.0
DTH2_k127_8337300_26 aminopeptidase N - - - 0.0000000000000000000000000000000000004697 158.0
DTH2_k127_8337300_27 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000005185 141.0
DTH2_k127_8337300_28 SWIB/MDM2 domain K03169 - 5.99.1.2 0.0000000000000000000000000000000001134 138.0
DTH2_k127_8337300_29 Regulatory protein, FmdB family - - - 0.00000000000000000000000000002969 122.0
DTH2_k127_8337300_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.199e-236 747.0
DTH2_k127_8337300_30 - - - - 0.0000000000000000000000000002965 116.0
DTH2_k127_8337300_31 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000001837 118.0
DTH2_k127_8337300_32 Copper binding periplasmic protein CusF - - - 0.0000000000000000000001473 102.0
DTH2_k127_8337300_33 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000129 94.0
DTH2_k127_8337300_34 Acetyltransferase (GNAT) domain - - - 0.000000000000000004994 91.0
DTH2_k127_8337300_35 PFAM CBS domain containing protein - - - 0.000000000000002941 89.0
DTH2_k127_8337300_36 PFAM Copper binding periplasmic protein CusF - - - 0.000000000001224 72.0
DTH2_k127_8337300_37 Copper resistance protein - - - 0.00006446 52.0
DTH2_k127_8337300_38 - - - - 0.0004809 47.0
DTH2_k127_8337300_4 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 2.96e-231 728.0
DTH2_k127_8337300_5 Multicopper oxidase K22348 - 1.16.3.3 6.815e-219 687.0
DTH2_k127_8337300_6 B12 binding domain - - - 7.423e-205 653.0
DTH2_k127_8337300_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 593.0
DTH2_k127_8337300_8 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 550.0
DTH2_k127_8337300_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 498.0
DTH2_k127_844443_0 prolyl oligopeptidase K01322 - 3.4.21.26 6.893e-214 685.0
DTH2_k127_844443_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 419.0
DTH2_k127_844443_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000001137 226.0
DTH2_k127_844443_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000001419 149.0
DTH2_k127_844443_4 - - - - 0.000000000000000000000000000000002206 136.0
DTH2_k127_8588264_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000002475 232.0
DTH2_k127_8588264_1 Histidine kinase K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000008178 229.0
DTH2_k127_8588264_2 BON domain K04065 - - 0.00000000000000000000000000000000005827 136.0
DTH2_k127_8588264_3 Bacterioferritin K03594 - 1.16.3.1 0.000000000000000000000000000001221 128.0
DTH2_k127_8588264_4 CsbD-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000006439 76.0
DTH2_k127_8588264_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000478 66.0
DTH2_k127_8588264_6 SMART Transport-associated and nodulation - - - 0.0000000007142 65.0
DTH2_k127_8588264_7 cheY-homologous receiver domain - - - 0.000000001312 70.0
DTH2_k127_8588264_8 PFAM glutaredoxin - - - 0.000000004148 57.0
DTH2_k127_8595064_0 ABC transporter C-terminal domain K06158 - - 1.948e-260 816.0
DTH2_k127_8595064_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 528.0
DTH2_k127_8595064_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 501.0
DTH2_k127_8595064_3 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 380.0
DTH2_k127_8595064_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
DTH2_k127_8595064_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 346.0
DTH2_k127_8595064_6 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
DTH2_k127_8595064_7 Protein of unknown function (DUF1847) - - - 0.0000000000000001533 86.0
DTH2_k127_8595064_8 Protein of unknown function (DUF1847) - - - 0.000000001951 62.0
DTH2_k127_8595064_9 Protein of unknown function (DUF1847) - - - 0.0005809 42.0
DTH2_k127_863292_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 486.0
DTH2_k127_863292_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 395.0
DTH2_k127_863292_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 335.0
DTH2_k127_863292_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000001305 71.0
DTH2_k127_863292_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000007112 48.0
DTH2_k127_8667493_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1965.0
DTH2_k127_8667493_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000006769 59.0
DTH2_k127_884578_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.396e-239 744.0
DTH2_k127_884578_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.782e-238 750.0
DTH2_k127_884578_10 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 382.0
DTH2_k127_884578_11 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 362.0
DTH2_k127_884578_12 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 358.0
DTH2_k127_884578_13 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 326.0
DTH2_k127_884578_14 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 309.0
DTH2_k127_884578_15 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 295.0
DTH2_k127_884578_16 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 290.0
DTH2_k127_884578_17 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000001903 214.0
DTH2_k127_884578_18 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000006771 211.0
DTH2_k127_884578_19 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000002798 185.0
DTH2_k127_884578_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 4.225e-230 751.0
DTH2_k127_884578_20 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000001253 178.0
DTH2_k127_884578_21 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.000000000000000000000000000000000000000000004776 175.0
DTH2_k127_884578_22 Type II secretion system protein B K02451 - - 0.0000000000000000000000000000000000000000004881 166.0
DTH2_k127_884578_23 GYD domain - - - 0.0000000000000000000000000001378 117.0
DTH2_k127_884578_24 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000001735 91.0
DTH2_k127_884578_25 - - - - 0.0000000000000000000421 95.0
DTH2_k127_884578_26 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000001712 65.0
DTH2_k127_884578_27 Transcriptional regulator - - - 0.00000002806 58.0
DTH2_k127_884578_28 SnoaL-like domain - - - 0.00000004146 64.0
DTH2_k127_884578_3 Type II secretory pathway, component ExeA K02450 - - 3.837e-198 634.0
DTH2_k127_884578_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 617.0
DTH2_k127_884578_5 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 542.0
DTH2_k127_884578_6 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 457.0
DTH2_k127_884578_7 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 468.0
DTH2_k127_884578_8 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 434.0
DTH2_k127_884578_9 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
DTH2_k127_8849746_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 485.0
DTH2_k127_8849746_1 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 464.0
DTH2_k127_8849746_2 Nitrate transport ATP-binding protein NrtC domain-containing protein 1 K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 400.0
DTH2_k127_8849746_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 335.0
DTH2_k127_8899216_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1138.0
DTH2_k127_8899216_1 ABC transporter transmembrane region K06147 - - 4.67e-265 828.0
DTH2_k127_8899216_10 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 543.0
DTH2_k127_8899216_11 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 525.0
DTH2_k127_8899216_12 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 524.0
DTH2_k127_8899216_13 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 449.0
DTH2_k127_8899216_14 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 436.0
DTH2_k127_8899216_15 acid transport system permease K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 388.0
DTH2_k127_8899216_16 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
DTH2_k127_8899216_17 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 355.0
DTH2_k127_8899216_18 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 351.0
DTH2_k127_8899216_19 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
DTH2_k127_8899216_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 4.986e-261 815.0
DTH2_k127_8899216_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001616 272.0
DTH2_k127_8899216_21 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005704 239.0
DTH2_k127_8899216_22 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
DTH2_k127_8899216_24 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000002338 196.0
DTH2_k127_8899216_25 AsnC family transcriptional regulator K03719 - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
DTH2_k127_8899216_26 - - - - 0.0000000000000000000000000000000000000000007047 166.0
DTH2_k127_8899216_28 Histidine kinase - - - 0.000000000000000000000000000000001766 133.0
DTH2_k127_8899216_29 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000078 133.0
DTH2_k127_8899216_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.782e-254 796.0
DTH2_k127_8899216_30 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000000000000000000000006956 132.0
DTH2_k127_8899216_31 flagellar protein FliS K02422 - - 0.000000000000000000000000000001396 126.0
DTH2_k127_8899216_32 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000001047 93.0
DTH2_k127_8899216_33 ethanolamine kinase activity K07251 - 2.7.1.89 0.0000000000000000002927 102.0
DTH2_k127_8899216_34 Flagellar protein FliT K02423 - - 0.000000000000000001456 93.0
DTH2_k127_8899216_35 Aldo/keto reductase family - - - 0.0000000000000009428 78.0
DTH2_k127_8899216_36 - - - - 0.00000000000002327 82.0
DTH2_k127_8899216_37 Membrane - - - 0.00000000000102 77.0
DTH2_k127_8899216_38 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000001216 74.0
DTH2_k127_8899216_39 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000007652 72.0
DTH2_k127_8899216_4 Outer membrane protein beta-barrel family K02014 - - 2.913e-214 690.0
DTH2_k127_8899216_40 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000002711 66.0
DTH2_k127_8899216_41 Flagellar regulator YcgR - - - 0.00000002731 64.0
DTH2_k127_8899216_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.57e-198 627.0
DTH2_k127_8899216_6 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 604.0
DTH2_k127_8899216_7 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 578.0
DTH2_k127_8899216_8 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 580.0
DTH2_k127_8899216_9 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 546.0
DTH2_k127_8956924_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 566.0
DTH2_k127_8956924_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 472.0
DTH2_k127_8956924_2 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 457.0
DTH2_k127_8956924_3 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 406.0
DTH2_k127_8956924_4 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
DTH2_k127_8956924_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003307 283.0
DTH2_k127_8965983_0 4Fe-4S dicluster domain K18930 - - 0.0 1146.0
DTH2_k127_8965983_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1059.0
DTH2_k127_8965983_10 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 473.0
DTH2_k127_8965983_11 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 461.0
DTH2_k127_8965983_12 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 435.0
DTH2_k127_8965983_13 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
DTH2_k127_8965983_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 430.0
DTH2_k127_8965983_15 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
DTH2_k127_8965983_16 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 312.0
DTH2_k127_8965983_17 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 323.0
DTH2_k127_8965983_18 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 291.0
DTH2_k127_8965983_19 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001245 283.0
DTH2_k127_8965983_2 GGDEF domain - - - 1.449e-311 976.0
DTH2_k127_8965983_20 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 275.0
DTH2_k127_8965983_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001834 288.0
DTH2_k127_8965983_22 Protein of unknown function, DUF480 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004234 263.0
DTH2_k127_8965983_23 NADPH-quinone reductase (modulator of drug activity B) K00355,K11746,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000003864 227.0
DTH2_k127_8965983_24 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
DTH2_k127_8965983_25 CDGSH-type zinc finger. Function unknown. - - - 0.0000000000000000000000000000000000000000000000000000000001226 211.0
DTH2_k127_8965983_26 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000002086 205.0
DTH2_k127_8965983_27 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000000000221 205.0
DTH2_k127_8965983_28 reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000000000001526 203.0
DTH2_k127_8965983_29 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000004459 199.0
DTH2_k127_8965983_3 GGDEF domain - - - 3.815e-286 903.0
DTH2_k127_8965983_30 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000006494 198.0
DTH2_k127_8965983_31 PIN domain - - - 0.00000000000000000000000000000000000000000009692 162.0
DTH2_k127_8965983_32 OsmC-like protein - - - 0.00000000000000000000000000000000001942 140.0
DTH2_k127_8965983_33 CBS domain - - - 0.0000000000000000000000000000006355 132.0
DTH2_k127_8965983_34 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000002446 118.0
DTH2_k127_8965983_35 Histidine kinase K13246 - 3.1.4.52 0.00000000000000000000000001302 128.0
DTH2_k127_8965983_36 - - - - 0.00000000000000000000007587 106.0
DTH2_k127_8965983_37 reverse transcriptase - - - 0.0000000000000000000002264 102.0
DTH2_k127_8965983_38 - - - - 0.00000000000000000236 89.0
DTH2_k127_8965983_39 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00000000000000001238 84.0
DTH2_k127_8965983_4 Sodium/hydrogen exchanger family K03455,K11745,K11747 - - 1.425e-266 833.0
DTH2_k127_8965983_40 mRNA binding K07339 - - 0.00000000000000002099 81.0
DTH2_k127_8965983_41 positive regulation of growth - - - 0.00000000000002105 75.0
DTH2_k127_8965983_42 Transposase DDE domain group 1 - - - 0.0000000008907 63.0
DTH2_k127_8965983_44 - - - - 0.000002601 59.0
DTH2_k127_8965983_5 Subtilase family - - - 3.083e-258 817.0
DTH2_k127_8965983_6 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.543e-233 734.0
DTH2_k127_8965983_7 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.734e-230 723.0
DTH2_k127_8965983_8 Transposase DDE domain group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 581.0
DTH2_k127_8965983_9 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 537.0
DTH2_k127_896693_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1110.0
DTH2_k127_896693_1 GTP-binding protein K06207 - - 0.0 1019.0
DTH2_k127_896693_10 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000007131 203.0
DTH2_k127_896693_11 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000005179 177.0
DTH2_k127_896693_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000002619 164.0
DTH2_k127_896693_13 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000103 171.0
DTH2_k127_896693_14 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.0000000000000000000000000000000000000002466 160.0
DTH2_k127_896693_15 PFAM PIN domain - - - 0.00000000000000000000000000002788 121.0
DTH2_k127_896693_16 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.000000000000000000001222 96.0
DTH2_k127_896693_17 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.000000000000000004971 87.0
DTH2_k127_896693_18 Protein of unknown function (DUF2442) - - - 0.0000000000001147 75.0
DTH2_k127_896693_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000001777 56.0
DTH2_k127_896693_2 Participates in both transcription termination and antitermination K02600 - - 5.116e-212 669.0
DTH2_k127_896693_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 365.0
DTH2_k127_896693_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 330.0
DTH2_k127_896693_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000226 290.0
DTH2_k127_896693_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
DTH2_k127_896693_7 impB/mucB/samB family K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005675 292.0
DTH2_k127_896693_8 Damage-inducible protein DinB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001494 249.0
DTH2_k127_896693_9 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000001559 248.0
DTH2_k127_9001431_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 476.0
DTH2_k127_9001431_1 Efflux pump membrane transporter K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 436.0
DTH2_k127_9072614_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 346.0
DTH2_k127_9072614_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 328.0
DTH2_k127_9072614_2 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000001646 212.0
DTH2_k127_9072614_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000006121 143.0
DTH2_k127_9072614_4 Cytochrome C' - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000187 131.0
DTH2_k127_9167140_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1643.0
DTH2_k127_9167140_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1036.0
DTH2_k127_9167140_10 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 396.0
DTH2_k127_9167140_11 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 392.0
DTH2_k127_9167140_12 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 349.0
DTH2_k127_9167140_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 325.0
DTH2_k127_9167140_14 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 300.0
DTH2_k127_9167140_15 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 287.0
DTH2_k127_9167140_16 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001258 283.0
DTH2_k127_9167140_17 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001436 225.0
DTH2_k127_9167140_18 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000006065 218.0
DTH2_k127_9167140_19 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000006122 201.0
DTH2_k127_9167140_2 GMC oxidoreductase K03333 - 1.1.3.6 1.524e-296 915.0
DTH2_k127_9167140_20 Thioesterase K07107,K12500 - - 0.0000000000000000000000000000000000000000000000000005728 192.0
DTH2_k127_9167140_21 Ribbon-helix-helix domain - - - 0.000000000000000000000000000000000000000003401 157.0
DTH2_k127_9167140_22 SMART Cold shock protein K03704 - - 0.000000000000000000000000001916 112.0
DTH2_k127_9167140_23 - - - - 0.00000000000001199 82.0
DTH2_k127_9167140_25 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000001156 61.0
DTH2_k127_9167140_26 Antibiotic biosynthesis monooxygenase - - - 0.000004929 52.0
DTH2_k127_9167140_3 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 2.166e-216 679.0
DTH2_k127_9167140_4 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 1.779e-209 659.0
DTH2_k127_9167140_5 Transketolase, C-terminal domain K00167 - 1.2.4.4 7.289e-195 612.0
DTH2_k127_9167140_6 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 572.0
DTH2_k127_9167140_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 563.0
DTH2_k127_9167140_8 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 541.0
DTH2_k127_9167140_9 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 500.0
DTH2_k127_9171420_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.518e-231 730.0
DTH2_k127_9171420_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 540.0
DTH2_k127_9171420_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 333.0
DTH2_k127_9171420_11 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 305.0
DTH2_k127_9171420_12 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 293.0
DTH2_k127_9171420_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
DTH2_k127_9171420_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
DTH2_k127_9171420_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
DTH2_k127_9171420_16 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000007582 230.0
DTH2_k127_9171420_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
DTH2_k127_9171420_18 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003222 224.0
DTH2_k127_9171420_19 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
DTH2_k127_9171420_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 527.0
DTH2_k127_9171420_20 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000003528 213.0
DTH2_k127_9171420_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000001489 208.0
DTH2_k127_9171420_22 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000002003 198.0
DTH2_k127_9171420_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000001357 192.0
DTH2_k127_9171420_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000007431 169.0
DTH2_k127_9171420_25 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000001503 166.0
DTH2_k127_9171420_26 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000007947 167.0
DTH2_k127_9171420_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003194 150.0
DTH2_k127_9171420_28 Redoxin domain protein - - - 0.000000000000000000000000000000000000002222 153.0
DTH2_k127_9171420_29 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000006185 147.0
DTH2_k127_9171420_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 460.0
DTH2_k127_9171420_30 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000004856 145.0
DTH2_k127_9171420_31 S4 RNA-binding domain - - - 0.0000000000000000000000000000000000009591 144.0
DTH2_k127_9171420_32 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000008779 131.0
DTH2_k127_9171420_33 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000006508 130.0
DTH2_k127_9171420_34 Ribosomal protein L30 K02907 - - 0.00000000000000000009195 90.0
DTH2_k127_9171420_35 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000001755 83.0
DTH2_k127_9171420_36 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002176 73.0
DTH2_k127_9171420_37 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002828 72.0
DTH2_k127_9171420_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 456.0
DTH2_k127_9171420_5 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 427.0
DTH2_k127_9171420_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 387.0
DTH2_k127_9171420_7 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 366.0
DTH2_k127_9171420_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 337.0
DTH2_k127_9171420_9 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 335.0
DTH2_k127_9204600_0 oxidoreductase K04090 - 1.2.7.8 0.0 1645.0
DTH2_k127_9204600_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1180.0
DTH2_k127_9204600_10 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 507.0
DTH2_k127_9204600_11 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 500.0
DTH2_k127_9204600_12 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 490.0
DTH2_k127_9204600_13 Formate dehydrogenase N, transmembrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 475.0
DTH2_k127_9204600_14 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 462.0
DTH2_k127_9204600_15 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 430.0
DTH2_k127_9204600_16 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 388.0
DTH2_k127_9204600_17 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 346.0
DTH2_k127_9204600_18 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 344.0
DTH2_k127_9204600_19 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 331.0
DTH2_k127_9204600_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.13e-226 720.0
DTH2_k127_9204600_20 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 336.0
DTH2_k127_9204600_21 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 323.0
DTH2_k127_9204600_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 320.0
DTH2_k127_9204600_23 Pfam Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 312.0
DTH2_k127_9204600_24 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 304.0
DTH2_k127_9204600_25 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 304.0
DTH2_k127_9204600_26 Polyphosphate kinase 2 (PPK2) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 304.0
DTH2_k127_9204600_27 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 301.0
DTH2_k127_9204600_28 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 306.0
DTH2_k127_9204600_29 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002293 298.0
DTH2_k127_9204600_3 type II secretion system protein E K02454 - - 2.226e-208 657.0
DTH2_k127_9204600_30 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001017 280.0
DTH2_k127_9204600_31 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
DTH2_k127_9204600_32 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
DTH2_k127_9204600_33 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000008087 220.0
DTH2_k127_9204600_34 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000788 206.0
DTH2_k127_9204600_35 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
DTH2_k127_9204600_36 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001676 201.0
DTH2_k127_9204600_37 membrane - - - 0.000000000000000000000000000000000000000000000000000232 189.0
DTH2_k127_9204600_38 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000000000000000000000000000000000002392 192.0
DTH2_k127_9204600_39 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000007785 178.0
DTH2_k127_9204600_4 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.286e-202 637.0
DTH2_k127_9204600_40 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000006333 158.0
DTH2_k127_9204600_41 Type II secretion system (T2SS), protein N K02463 - - 0.0000000000000000000000000000000441 135.0
DTH2_k127_9204600_42 cell division protein - - - 0.000000000000000000000000000006914 127.0
DTH2_k127_9204600_43 - - - - 0.000000000000000000000000002239 120.0
DTH2_k127_9204600_44 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000002662 125.0
DTH2_k127_9204600_45 Glycine cleavage H-protein - - - 0.0000000000000000000000001716 112.0
DTH2_k127_9204600_46 general secretion pathway protein K02457 - - 0.000000000000000000000003463 108.0
DTH2_k127_9204600_47 Protein of unknown function (DUF3108) - - - 0.00000000000000000000005872 107.0
DTH2_k127_9204600_48 General secretion pathway K02462 - - 0.0000000000000000009169 92.0
DTH2_k127_9204600_49 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000965 86.0
DTH2_k127_9204600_5 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 617.0
DTH2_k127_9204600_50 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000003452 92.0
DTH2_k127_9204600_51 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000000004347 93.0
DTH2_k127_9204600_52 General secretion pathway protein L K02461 - - 0.00000000000000006133 94.0
DTH2_k127_9204600_53 DsrE/DsrF-like family - - - 0.0000000000000003111 83.0
DTH2_k127_9204600_54 exo-alpha-(2->6)-sialidase activity K01179,K01186,K12373,K17624 - 3.2.1.18,3.2.1.4,3.2.1.52,3.2.1.97 0.000000000000002503 78.0
DTH2_k127_9204600_55 helix_turn_helix ASNC type K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000148 73.0
DTH2_k127_9204600_56 general secretion pathway protein K02452 - - 0.000000000002887 76.0
DTH2_k127_9204600_58 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.000002807 59.0
DTH2_k127_9204600_59 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000003532 55.0
DTH2_k127_9204600_6 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 581.0
DTH2_k127_9204600_7 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 524.0
DTH2_k127_9204600_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 511.0
DTH2_k127_9204600_9 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 512.0
DTH2_k127_926178_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3199.0
DTH2_k127_926178_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 2.629e-281 878.0
DTH2_k127_926178_10 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 479.0
DTH2_k127_926178_11 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 471.0
DTH2_k127_926178_12 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 428.0
DTH2_k127_926178_13 ABC-type sugar transport system, permease component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 426.0
DTH2_k127_926178_14 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 406.0
DTH2_k127_926178_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 404.0
DTH2_k127_926178_16 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 381.0
DTH2_k127_926178_17 Vitamin k epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 369.0
DTH2_k127_926178_18 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 360.0
DTH2_k127_926178_19 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 366.0
DTH2_k127_926178_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 4.732e-212 670.0
DTH2_k127_926178_20 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 355.0
DTH2_k127_926178_21 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
DTH2_k127_926178_22 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 341.0
DTH2_k127_926178_23 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 320.0
DTH2_k127_926178_24 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 327.0
DTH2_k127_926178_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 291.0
DTH2_k127_926178_26 crp fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
DTH2_k127_926178_27 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007177 287.0
DTH2_k127_926178_28 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002813 275.0
DTH2_k127_926178_29 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009121 241.0
DTH2_k127_926178_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.991e-206 657.0
DTH2_k127_926178_30 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
DTH2_k127_926178_31 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000000002685 234.0
DTH2_k127_926178_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
DTH2_k127_926178_33 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
DTH2_k127_926178_34 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000004873 196.0
DTH2_k127_926178_35 Regulator K01420 - - 0.000000000000000000000000000000000000000000003111 178.0
DTH2_k127_926178_36 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000003496 172.0
DTH2_k127_926178_37 Rubrerythrin - - - 0.00000000000000000000000000000000000000169 154.0
DTH2_k127_926178_39 PFAM transport-associated K04065 - - 0.000000000000000000000000000000000001988 139.0
DTH2_k127_926178_4 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 594.0
DTH2_k127_926178_40 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001495 136.0
DTH2_k127_926178_41 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000469 133.0
DTH2_k127_926178_42 - - - - 0.000000000000000000000000000001788 125.0
DTH2_k127_926178_43 PFAM transport-associated K04065 - - 0.00000000000000000000000000007992 119.0
DTH2_k127_926178_44 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000002261 108.0
DTH2_k127_926178_45 - - - - 0.000000000000000000000002281 108.0
DTH2_k127_926178_46 7TM receptor with intracellular HD hydrolase - - - 0.00000000000000000000009101 102.0
DTH2_k127_926178_47 Glycine zipper 2TM domain K04062 - - 0.00000000000000000001196 98.0
DTH2_k127_926178_48 - - - - 0.00000000000000000919 92.0
DTH2_k127_926178_49 - - - - 0.000000000000009145 76.0
DTH2_k127_926178_5 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 587.0
DTH2_k127_926178_50 Protein of unknown function (DUF3096) - - - 0.00000000000002944 73.0
DTH2_k127_926178_51 ferredoxin - - - 0.00000000000009751 73.0
DTH2_k127_926178_52 Belongs to the UPF0337 (CsbD) family - - - 0.0000002285 57.0
DTH2_k127_926178_53 - - - - 0.0003371 47.0
DTH2_k127_926178_54 PFAM AMP-dependent synthetase and ligase - - - 0.0005623 44.0
DTH2_k127_926178_6 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 589.0
DTH2_k127_926178_7 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 562.0
DTH2_k127_926178_8 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 556.0
DTH2_k127_926178_9 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 532.0
DTH2_k127_9324407_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1624.0
DTH2_k127_9324407_1 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 377.0
DTH2_k127_9324407_2 PIN domain - - - 0.0000000000000000000000000000007552 126.0
DTH2_k127_9324407_3 - - - - 0.00000000000000000000000003967 113.0
DTH2_k127_9324407_4 - - - - 0.000000002186 63.0
DTH2_k127_9324407_5 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000005937 54.0
DTH2_k127_9345883_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1309.0
DTH2_k127_9345883_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1286.0
DTH2_k127_9345883_10 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 393.0
DTH2_k127_9345883_11 Bacterial regulatory proteins, crp family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 355.0
DTH2_k127_9345883_12 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 351.0
DTH2_k127_9345883_13 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 335.0
DTH2_k127_9345883_14 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 331.0
DTH2_k127_9345883_15 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 331.0
DTH2_k127_9345883_16 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
DTH2_k127_9345883_17 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000155 285.0
DTH2_k127_9345883_18 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002091 273.0
DTH2_k127_9345883_19 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
DTH2_k127_9345883_2 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 2.127e-320 987.0
DTH2_k127_9345883_20 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000252 257.0
DTH2_k127_9345883_21 NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000005548 223.0
DTH2_k127_9345883_22 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000007227 189.0
DTH2_k127_9345883_23 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000000001462 184.0
DTH2_k127_9345883_24 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000543 176.0
DTH2_k127_9345883_25 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000001265 175.0
DTH2_k127_9345883_26 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000009195 174.0
DTH2_k127_9345883_27 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.000000000000000000000000000000000000000000002966 166.0
DTH2_k127_9345883_28 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000006932 166.0
DTH2_k127_9345883_29 - - - - 0.000000000000000000000000000000000000000004092 158.0
DTH2_k127_9345883_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.317e-268 831.0
DTH2_k127_9345883_30 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000001696 152.0
DTH2_k127_9345883_31 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000134 140.0
DTH2_k127_9345883_32 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000001016 124.0
DTH2_k127_9345883_33 - - - - 0.000000000000000000000000001374 115.0
DTH2_k127_9345883_34 FixH family K09926 - - 0.000000000000000000000000005559 117.0
DTH2_k127_9345883_35 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000003917 111.0
DTH2_k127_9345883_36 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000005397 98.0
DTH2_k127_9345883_37 cellulase activity - - - 0.00000000000000000003907 105.0
DTH2_k127_9345883_38 Cbb3-type cytochrome oxidase K00407 - - 0.000000000000002591 76.0
DTH2_k127_9345883_39 cytochrome oxidase maturation protein cbb3-type - - - 0.000000008964 59.0
DTH2_k127_9345883_4 Domain of unknown function (DUF5117) - - - 9.915e-213 692.0
DTH2_k127_9345883_5 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 586.0
DTH2_k127_9345883_6 cytochrome C oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 587.0
DTH2_k127_9345883_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 586.0
DTH2_k127_9345883_8 Heavy-metal-associated domain K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 497.0
DTH2_k127_9345883_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 415.0
DTH2_k127_9369220_0 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006153 288.0
DTH2_k127_9369220_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002455 275.0
DTH2_k127_9369220_10 - - - - 0.000000000000000002091 85.0
DTH2_k127_9369220_11 Domain of unknown function (DUF4387) - - - 0.000000000000007536 74.0
DTH2_k127_9369220_12 peptidase - - - 0.000000000007652 66.0
DTH2_k127_9369220_13 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000001837 64.0
DTH2_k127_9369220_14 peptidase - - - 0.00000009073 61.0
DTH2_k127_9369220_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000778 261.0
DTH2_k127_9369220_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000007369 180.0
DTH2_k127_9369220_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000005318 170.0
DTH2_k127_9369220_5 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000001292 143.0
DTH2_k127_9369220_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000001499 129.0
DTH2_k127_9369220_7 Transcriptional regulator - - - 0.000000000000000000000000000008465 123.0
DTH2_k127_9369220_8 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000002857 124.0
DTH2_k127_9369220_9 Plasmid stability protein K21495 - - 0.0000000000000000003696 92.0
DTH2_k127_9406931_0 Protein of unknown function - - - 4.258e-277 900.0
DTH2_k127_9406931_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 8.15e-266 850.0
DTH2_k127_9406931_10 - - - - 0.000000000002766 77.0
DTH2_k127_9406931_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 4.031e-215 685.0
DTH2_k127_9406931_3 peptidase U62, modulator of DNA gyrase K03568 - - 4.889e-213 674.0
DTH2_k127_9406931_4 Secretin and TonB N terminus short domain K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 554.0
DTH2_k127_9406931_5 PFAM type II secretion system K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 397.0
DTH2_k127_9406931_6 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 378.0
DTH2_k127_9406931_7 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000005 214.0
DTH2_k127_9406931_8 Pilus assembly protein, PilO - - - 0.000000000000000001034 99.0
DTH2_k127_9406931_9 - - - - 0.0000000000005548 78.0
DTH2_k127_9409318_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2725.0
DTH2_k127_9409318_1 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1358.0
DTH2_k127_9409318_10 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 522.0
DTH2_k127_9409318_11 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 495.0
DTH2_k127_9409318_12 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
DTH2_k127_9409318_13 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 484.0
DTH2_k127_9409318_14 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 455.0
DTH2_k127_9409318_15 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 439.0
DTH2_k127_9409318_16 COG3436 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 427.0
DTH2_k127_9409318_17 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 426.0
DTH2_k127_9409318_18 Dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 406.0
DTH2_k127_9409318_19 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 398.0
DTH2_k127_9409318_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.359e-240 753.0
DTH2_k127_9409318_20 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 385.0
DTH2_k127_9409318_21 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 365.0
DTH2_k127_9409318_22 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 367.0
DTH2_k127_9409318_23 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 355.0
DTH2_k127_9409318_24 Type ii and iii secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 297.0
DTH2_k127_9409318_25 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
DTH2_k127_9409318_26 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004332 240.0
DTH2_k127_9409318_27 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
DTH2_k127_9409318_28 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000003445 213.0
DTH2_k127_9409318_29 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000004232 198.0
DTH2_k127_9409318_3 Penicillin amidase K01434 - 3.5.1.11 1.156e-235 755.0
DTH2_k127_9409318_30 nucleoside-diphosphate sugar epimerase - - - 0.00000000000000000000000000000000000000000000005348 177.0
DTH2_k127_9409318_31 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000000000000001714 162.0
DTH2_k127_9409318_32 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000104 126.0
DTH2_k127_9409318_33 - - - - 0.000000000000000000000000002836 112.0
DTH2_k127_9409318_34 Protein of unknown function (DUF2283) - - - 0.000000000000000000000002838 104.0
DTH2_k127_9409318_35 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000481 102.0
DTH2_k127_9409318_36 Histidine kinase - - - 0.000000000000000000004341 95.0
DTH2_k127_9409318_37 Unextendable partial coding region - - - 0.000000000000000005013 83.0
DTH2_k127_9409318_39 - - - - 0.00000000000001169 80.0
DTH2_k127_9409318_4 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 1.626e-222 702.0
DTH2_k127_9409318_40 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000002171 71.0
DTH2_k127_9409318_41 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000001112 64.0
DTH2_k127_9409318_42 copG family - - - 0.0000000001697 65.0
DTH2_k127_9409318_5 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 1.426e-215 683.0
DTH2_k127_9409318_6 Magnesium transport protein CorA - - - 1.589e-205 662.0
DTH2_k127_9409318_7 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 583.0
DTH2_k127_9409318_8 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 526.0
DTH2_k127_9409318_9 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 523.0
DTH2_k127_940938_0 alcohol dehydrogenase K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 443.0
DTH2_k127_940938_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 411.0
DTH2_k127_940938_2 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000001291 242.0
DTH2_k127_940938_3 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 0.000000000000000000000000000003425 126.0
DTH2_k127_9433802_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000002259 207.0
DTH2_k127_9434517_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1533.0
DTH2_k127_9434517_1 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1277.0
DTH2_k127_9434517_10 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 386.0
DTH2_k127_9434517_11 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 402.0
DTH2_k127_9434517_12 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002831 259.0
DTH2_k127_9434517_13 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000003586 251.0
DTH2_k127_9434517_14 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001156 237.0
DTH2_k127_9434517_15 carbohydrate transport K11688 - - 0.000000000000000000000000000000000000000000000000000000000000001079 231.0
DTH2_k127_9434517_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
DTH2_k127_9434517_17 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000004504 208.0
DTH2_k127_9434517_18 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000007504 191.0
DTH2_k127_9434517_19 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000003273 152.0
DTH2_k127_9434517_2 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 627.0
DTH2_k127_9434517_20 NUDIX domain - - - 0.00000000000000000000000000005348 124.0
DTH2_k127_9434517_21 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000005403 99.0
DTH2_k127_9434517_22 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000361 95.0
DTH2_k127_9434517_23 - - - - 0.0000001226 63.0
DTH2_k127_9434517_24 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000004319 50.0
DTH2_k127_9434517_25 family) member 1 - - - 0.0005305 48.0
DTH2_k127_9434517_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 595.0
DTH2_k127_9434517_4 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 545.0
DTH2_k127_9434517_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
DTH2_k127_9434517_6 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071704,GO:1901564 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 461.0
DTH2_k127_9434517_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 429.0
DTH2_k127_9434517_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 433.0
DTH2_k127_9434517_9 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 416.0
DTH2_k127_9535631_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0 1135.0
DTH2_k127_9535631_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.878e-314 973.0
DTH2_k127_9535631_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003645 237.0
DTH2_k127_9535631_11 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000001242 227.0
DTH2_k127_9535631_12 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001893 231.0
DTH2_k127_9535631_13 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000006241 218.0
DTH2_k127_9535631_14 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000004768 210.0
DTH2_k127_9535631_15 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000002677 156.0
DTH2_k127_9535631_16 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.00000000000000001338 83.0
DTH2_k127_9535631_17 metal cluster binding K03497 - - 0.00000000000000006903 85.0
DTH2_k127_9535631_18 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000005574 58.0
DTH2_k127_9535631_2 heat shock protein binding - - - 5.794e-266 834.0
DTH2_k127_9535631_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 2.967e-242 769.0
DTH2_k127_9535631_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 585.0
DTH2_k127_9535631_5 Decaheme c-type cytochrome, DmsE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 430.0
DTH2_k127_9535631_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 364.0
DTH2_k127_9535631_7 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 299.0
DTH2_k127_9535631_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
DTH2_k127_9535631_9 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003644 241.0
DTH2_k127_9555182_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1567.0
DTH2_k127_9555182_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1429.0
DTH2_k127_9555182_10 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.901e-222 694.0
DTH2_k127_9555182_11 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.817e-219 687.0
DTH2_k127_9555182_12 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.02e-216 681.0
DTH2_k127_9555182_13 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 9.954e-210 668.0
DTH2_k127_9555182_14 helicase K03722 - 3.6.4.12 2.855e-199 642.0
DTH2_k127_9555182_15 Belongs to the thiolase family K00626 - 2.3.1.9 7.479e-199 627.0
DTH2_k127_9555182_16 Belongs to the thiolase family K00626 - 2.3.1.9 8.355e-195 613.0
DTH2_k127_9555182_17 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 600.0
DTH2_k127_9555182_18 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 567.0
DTH2_k127_9555182_19 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 568.0
DTH2_k127_9555182_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1302.0
DTH2_k127_9555182_20 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 565.0
DTH2_k127_9555182_21 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 554.0
DTH2_k127_9555182_22 Dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 518.0
DTH2_k127_9555182_23 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 505.0
DTH2_k127_9555182_24 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 500.0
DTH2_k127_9555182_25 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 484.0
DTH2_k127_9555182_26 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 446.0
DTH2_k127_9555182_27 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 444.0
DTH2_k127_9555182_28 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
DTH2_k127_9555182_29 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 408.0
DTH2_k127_9555182_3 5-oxoprolinase K01469 - 3.5.2.9 0.0 1072.0
DTH2_k127_9555182_30 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 402.0
DTH2_k127_9555182_31 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
DTH2_k127_9555182_32 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 369.0
DTH2_k127_9555182_33 GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 352.0
DTH2_k127_9555182_34 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 338.0
DTH2_k127_9555182_35 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 347.0
DTH2_k127_9555182_36 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 320.0
DTH2_k127_9555182_37 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 298.0
DTH2_k127_9555182_38 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 304.0
DTH2_k127_9555182_39 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 293.0
DTH2_k127_9555182_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.14e-321 993.0
DTH2_k127_9555182_40 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
DTH2_k127_9555182_41 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 282.0
DTH2_k127_9555182_42 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005148 297.0
DTH2_k127_9555182_43 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
DTH2_k127_9555182_44 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001066 264.0
DTH2_k127_9555182_45 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000007543 242.0
DTH2_k127_9555182_46 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000002079 239.0
DTH2_k127_9555182_47 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000003185 235.0
DTH2_k127_9555182_48 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000007846 234.0
DTH2_k127_9555182_49 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
DTH2_k127_9555182_5 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.958e-317 978.0
DTH2_k127_9555182_50 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000001243 202.0
DTH2_k127_9555182_51 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000002957 198.0
DTH2_k127_9555182_52 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000003115 199.0
DTH2_k127_9555182_53 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000000004931 183.0
DTH2_k127_9555182_54 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.00000000000000000000000000000000000000001372 155.0
DTH2_k127_9555182_55 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000003095 154.0
DTH2_k127_9555182_56 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000003788 149.0
DTH2_k127_9555182_57 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000009614 148.0
DTH2_k127_9555182_58 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000006057 104.0
DTH2_k127_9555182_59 Protein of unknown function (DUF465) - - - 0.0000000000000002821 80.0
DTH2_k127_9555182_6 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.225e-314 977.0
DTH2_k127_9555182_60 - - - - 0.000000000000001346 87.0
DTH2_k127_9555182_61 - - - - 0.00000000000004463 76.0
DTH2_k127_9555182_63 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0003809 48.0
DTH2_k127_9555182_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.185e-249 776.0
DTH2_k127_9555182_8 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.267e-239 747.0
DTH2_k127_9555182_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.173e-226 708.0
DTH2_k127_9625153_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 3.602e-262 829.0
DTH2_k127_9625153_1 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 2.581e-231 727.0
DTH2_k127_9625153_10 gnat family - - - 0.000000005892 62.0
DTH2_k127_9625153_11 Galactose binding lectin domain - - - 0.00000005661 60.0
DTH2_k127_9625153_12 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.000001454 55.0
DTH2_k127_9625153_13 DnaJ domain protein - - - 0.0004557 49.0
DTH2_k127_9625153_2 dehydrogenase K00253 - 1.3.8.4 3.921e-222 692.0
DTH2_k127_9625153_3 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 443.0
DTH2_k127_9625153_4 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 415.0
DTH2_k127_9625153_5 threonine dehydratase K17989 GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.17,4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 366.0
DTH2_k127_9625153_6 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001172 289.0
DTH2_k127_9625153_7 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000006287 188.0
DTH2_k127_9625153_8 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000001616 179.0
DTH2_k127_9625153_9 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000003744 140.0
DTH2_k127_987649_0 amidohydrolase K01451 - 3.5.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 564.0
DTH2_k127_987649_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 396.0
DTH2_k127_9890310_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1694.0
DTH2_k127_9890310_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1429.0
DTH2_k127_9890310_10 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 521.0
DTH2_k127_9890310_11 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 463.0
DTH2_k127_9890310_12 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 446.0
DTH2_k127_9890310_13 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 422.0
DTH2_k127_9890310_14 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
DTH2_k127_9890310_15 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 395.0
DTH2_k127_9890310_16 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 382.0
DTH2_k127_9890310_17 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 381.0
DTH2_k127_9890310_18 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 385.0
DTH2_k127_9890310_19 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
DTH2_k127_9890310_2 PQQ enzyme repeat - - - 5.131e-301 932.0
DTH2_k127_9890310_20 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 361.0
DTH2_k127_9890310_21 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 348.0
DTH2_k127_9890310_22 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 342.0
DTH2_k127_9890310_23 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 333.0
DTH2_k127_9890310_24 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 348.0
DTH2_k127_9890310_25 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 314.0
DTH2_k127_9890310_26 PFAM multicopper oxidase type K04753,K08100,K14588 - 1.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 319.0
DTH2_k127_9890310_27 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
DTH2_k127_9890310_28 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002614 285.0
DTH2_k127_9890310_29 Proteasome subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
DTH2_k127_9890310_3 Peptidase family M3 K01414 - 3.4.24.70 1.113e-281 889.0
DTH2_k127_9890310_30 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 262.0
DTH2_k127_9890310_31 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006777 264.0
DTH2_k127_9890310_32 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000004001 244.0
DTH2_k127_9890310_33 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000003536 232.0
DTH2_k127_9890310_34 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000000002781 214.0
DTH2_k127_9890310_35 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000000000000000000000000000000000000000000007227 206.0
DTH2_k127_9890310_36 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000003882 209.0
DTH2_k127_9890310_37 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000004573 217.0
DTH2_k127_9890310_38 Ankyrin repeats (3 copies) K06867,K21440 - - 0.000000000000000000000000000000000000000000000000000302 192.0
DTH2_k127_9890310_39 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000006174 202.0
DTH2_k127_9890310_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 8.725e-269 841.0
DTH2_k127_9890310_40 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000002885 165.0
DTH2_k127_9890310_41 Belongs to the 'phage' integrase family K14059 - - 0.00000000000000000000000000000000000000000000941 169.0
DTH2_k127_9890310_42 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000002751 164.0
DTH2_k127_9890310_43 - - - - 0.000000000000000000000000000000000000000007163 163.0
DTH2_k127_9890310_44 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000127 150.0
DTH2_k127_9890310_45 Adenylate cyclase - - - 0.000000000000000000000000000000000001026 147.0
DTH2_k127_9890310_46 TIGRFAM phasin family protein - - - 0.00000000000000000000000000000000001019 143.0
DTH2_k127_9890310_47 PFAM Glutaredoxin - - - 0.0000000000000000000000000000000007219 141.0
DTH2_k127_9890310_48 Cro/C1-type HTH DNA-binding domain K07727 - - 0.000000000000000000000001013 108.0
DTH2_k127_9890310_49 - - - - 0.0000000000000000000007265 104.0
DTH2_k127_9890310_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.319e-247 786.0
DTH2_k127_9890310_50 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000007405 101.0
DTH2_k127_9890310_52 - - - - 0.00000000002528 64.0
DTH2_k127_9890310_53 - - - - 0.0000000004449 60.0
DTH2_k127_9890310_54 Bacteriophage replication gene A protein (GPA) - - - 0.000000002371 66.0
DTH2_k127_9890310_55 phospholipase C - - - 0.0006987 53.0
DTH2_k127_9890310_6 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 1.043e-223 703.0
DTH2_k127_9890310_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 1.043e-210 669.0
DTH2_k127_9890310_8 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 603.0
DTH2_k127_9890310_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 602.0