Overview

ID MAG00764
Name DTH2_bin.21
Sample SMP0023
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus JAJYIS01
Species
Assembly information
Completeness (%) 98.06
Contamination (%) 1.5
GC content (%) 57.0
N50 (bp) 33,932
Genome size (bp) 1,696,185

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1512

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_1050560_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 588.0
DTH2_k127_1050560_1 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 373.0
DTH2_k127_1050560_10 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000002781 117.0
DTH2_k127_1050560_11 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000008694 110.0
DTH2_k127_1050560_12 PFAM glutaredoxin - - - 0.00000000000000001499 87.0
DTH2_k127_1050560_13 SCP-2 sterol transfer family - - - 0.0000000000000000399 85.0
DTH2_k127_1050560_14 negative regulation of guanyl-nucleotide exchange factor activity K15837,K15839 GO:0000132,GO:0000139,GO:0000226,GO:0000278,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005886,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007163,GO:0007275,GO:0007399,GO:0007400,GO:0007405,GO:0008047,GO:0008104,GO:0008150,GO:0008277,GO:0008283,GO:0008356,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009987,GO:0010506,GO:0010508,GO:0010646,GO:0012505,GO:0014016,GO:0014017,GO:0016020,GO:0016043,GO:0016239,GO:0016241,GO:0017145,GO:0019222,GO:0019904,GO:0022008,GO:0022402,GO:0023051,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0031984,GO:0032091,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0034260,GO:0036445,GO:0040001,GO:0042175,GO:0043085,GO:0043086,GO:0043087,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043547,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0048103,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0051098,GO:0051099,GO:0051100,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051346,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0055057,GO:0055059,GO:0060259,GO:0060589,GO:0061351,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071840,GO:0071944,GO:0072089,GO:0098588,GO:0098722,GO:0098772,GO:0098791,GO:0098827,GO:0099568,GO:0099738,GO:1902850,GO:1903047,GO:1904424,GO:1905097,GO:1905098 - 0.000000000004463 79.0
DTH2_k127_1050560_15 tetratricopeptide repeat - - - 0.0000008499 57.0
DTH2_k127_1050560_16 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.0003116 44.0
DTH2_k127_1050560_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 323.0
DTH2_k127_1050560_3 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 316.0
DTH2_k127_1050560_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000001908 227.0
DTH2_k127_1050560_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000001402 209.0
DTH2_k127_1050560_6 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000001867 173.0
DTH2_k127_1050560_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000006033 138.0
DTH2_k127_1050560_9 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000000009719 126.0
DTH2_k127_109841_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 335.0
DTH2_k127_109841_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000003636 201.0
DTH2_k127_109841_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001069 174.0
DTH2_k127_109841_3 SIS domain K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000002102 173.0
DTH2_k127_109841_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000007367 141.0
DTH2_k127_109841_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001691 133.0
DTH2_k127_109841_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000001072 98.0
DTH2_k127_109841_7 Proteasome regulatory subunit K03030 - - 0.00000000002905 70.0
DTH2_k127_1116144_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 343.0
DTH2_k127_1116144_1 Cysteine desulfurase - - - 0.000000000000000000000000000000000000000000000000000000001369 216.0
DTH2_k127_1116144_2 - - - - 0.000000000000000000000000000000000000000000000000001685 192.0
DTH2_k127_1116144_3 Flavodoxin - - - 0.0000000000000000000000000000000005351 138.0
DTH2_k127_1116144_4 - - - - 0.00000000000000005967 87.0
DTH2_k127_1116144_5 NAD-dependent epimerase dehydratase - - - 0.000000000000000818 85.0
DTH2_k127_1116144_6 acetyltransferase - - - 0.000000000000002668 87.0
DTH2_k127_1116144_7 COG0598 Mg2 and Co2 transporters K03284 - - 0.0000000000199 73.0
DTH2_k127_1116144_8 YoaP-like - - - 0.000000002957 67.0
DTH2_k127_1116144_9 FMN binding - - - 0.0000002962 58.0
DTH2_k127_128662_0 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 568.0
DTH2_k127_128662_1 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 564.0
DTH2_k127_128662_10 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002696 292.0
DTH2_k127_128662_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000709 248.0
DTH2_k127_128662_12 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000001979 247.0
DTH2_k127_128662_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000001937 236.0
DTH2_k127_128662_14 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
DTH2_k127_128662_15 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000002638 233.0
DTH2_k127_128662_16 PhoU domain - - - 0.0000000000000000000000000000000000000000000000000000000006214 214.0
DTH2_k127_128662_17 transferase activity, transferring glycosyl groups K13678 GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 - 0.00000000000000000000000000000000000000000000000000006148 201.0
DTH2_k127_128662_18 PFAM amidinotransferase K01478,K01482 - 3.5.3.18,3.5.3.6 0.0000000000000000000000000000000000000000000000000001746 194.0
DTH2_k127_128662_19 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000013 164.0
DTH2_k127_128662_2 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 421.0
DTH2_k127_128662_21 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000003788 139.0
DTH2_k127_128662_22 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000001936 135.0
DTH2_k127_128662_23 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000001307 90.0
DTH2_k127_128662_24 - K00960 - 2.7.7.6 0.00000000000000001398 86.0
DTH2_k127_128662_25 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000001587 86.0
DTH2_k127_128662_26 - - - - 0.0000000001384 66.0
DTH2_k127_128662_27 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000003857 59.0
DTH2_k127_128662_28 Protein of unknown function (DUF3795) - - - 0.00005745 53.0
DTH2_k127_128662_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 400.0
DTH2_k127_128662_4 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 352.0
DTH2_k127_128662_6 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
DTH2_k127_128662_7 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 299.0
DTH2_k127_128662_8 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001274 287.0
DTH2_k127_128662_9 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000178 289.0
DTH2_k127_1303790_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 481.0
DTH2_k127_1303790_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 404.0
DTH2_k127_1303790_2 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 381.0
DTH2_k127_1303790_3 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 355.0
DTH2_k127_1303790_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 265.0
DTH2_k127_1303790_5 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
DTH2_k127_1303790_6 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000002391 78.0
DTH2_k127_1303790_7 - - - - 0.00000000000004108 79.0
DTH2_k127_1303790_8 Belongs to the ompA family K20276 - - 0.0000000000171 74.0
DTH2_k127_1303790_9 Transcriptional regulator K07108 - - 0.000003021 54.0
DTH2_k127_1318194_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 422.0
DTH2_k127_1318194_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 336.0
DTH2_k127_1318194_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000001042 80.0
DTH2_k127_1318194_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00009202 51.0
DTH2_k127_1318194_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
DTH2_k127_1318194_3 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000005163 224.0
DTH2_k127_1318194_4 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000001021 213.0
DTH2_k127_1318194_5 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000001396 182.0
DTH2_k127_1318194_6 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000668 180.0
DTH2_k127_1318194_7 CcmB protein K02194 - - 0.000000000000000000000000000000000000000000006345 172.0
DTH2_k127_1318194_8 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000001091 121.0
DTH2_k127_1318194_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000003835 82.0
DTH2_k127_1391113_0 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 616.0
DTH2_k127_1391113_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 461.0
DTH2_k127_1391113_10 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005179 256.0
DTH2_k127_1391113_11 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000001138 245.0
DTH2_k127_1391113_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000001259 255.0
DTH2_k127_1391113_13 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000002976 224.0
DTH2_k127_1391113_14 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family - - - 0.000000000000000000000000000000000000000000000000000006065 198.0
DTH2_k127_1391113_15 B12 binding domain K14084 - - 0.000000000000000000000000000000000000000000000000001068 192.0
DTH2_k127_1391113_16 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000009069 188.0
DTH2_k127_1391113_17 transcription regulator activity - - - 0.000000000000000000000000000000000000000002719 159.0
DTH2_k127_1391113_18 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000000000000000001151 172.0
DTH2_k127_1391113_19 Bacterial Ig-like domain (group 1) - - - 0.00000000000000000001469 109.0
DTH2_k127_1391113_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 409.0
DTH2_k127_1391113_20 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000002352 85.0
DTH2_k127_1391113_21 Protein of unknown function (DUF835) - - - 0.00000000000447 78.0
DTH2_k127_1391113_22 Protein of unknown function (DUF835) - - - 0.000000001916 66.0
DTH2_k127_1391113_23 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0008296 49.0
DTH2_k127_1391113_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 336.0
DTH2_k127_1391113_4 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 318.0
DTH2_k127_1391113_5 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005614 282.0
DTH2_k127_1391113_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001032 265.0
DTH2_k127_1391113_7 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000003385 265.0
DTH2_k127_1391113_8 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000008046 256.0
DTH2_k127_1391113_9 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000000001514 259.0
DTH2_k127_1477705_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 1.879e-206 652.0
DTH2_k127_1477705_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 373.0
DTH2_k127_1477705_2 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000000000000000000009958 158.0
DTH2_k127_1477705_3 Pfam:DUF552 K09152 - - 0.00000000000000000000000005288 108.0
DTH2_k127_1477705_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000227 73.0
DTH2_k127_1477705_5 SPFH domain-Band 7 family - - - 0.0003108 48.0
DTH2_k127_1477705_6 Double zinc ribbon - - - 0.0006346 50.0
DTH2_k127_1528910_0 DNA polymerase type-B family K02319 - 2.7.7.7 4.22e-259 821.0
DTH2_k127_1528910_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 523.0
DTH2_k127_1528910_10 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001023 232.0
DTH2_k127_1528910_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004043 229.0
DTH2_k127_1528910_12 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000002678 181.0
DTH2_k127_1528910_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000004374 181.0
DTH2_k127_1528910_14 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000001473 158.0
DTH2_k127_1528910_15 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000006938 142.0
DTH2_k127_1528910_16 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000001321 111.0
DTH2_k127_1528910_17 RNA polymerase K03051 - 2.7.7.6 0.000000000000000000002146 97.0
DTH2_k127_1528910_2 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 471.0
DTH2_k127_1528910_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 473.0
DTH2_k127_1528910_4 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 442.0
DTH2_k127_1528910_5 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 347.0
DTH2_k127_1528910_6 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 319.0
DTH2_k127_1528910_7 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000004695 253.0
DTH2_k127_1528910_8 Helix-hairpin-helix motif K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000003739 238.0
DTH2_k127_1528910_9 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000001985 238.0
DTH2_k127_1576856_0 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 466.0
DTH2_k127_1576856_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 319.0
DTH2_k127_1576856_2 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
DTH2_k127_1576856_3 Peptidase family M28 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000842 170.0
DTH2_k127_1576856_4 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000002139 151.0
DTH2_k127_1576856_5 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000002055 119.0
DTH2_k127_1576856_6 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000001687 102.0
DTH2_k127_1576856_7 GNaT family - - - 0.0000000000000006814 85.0
DTH2_k127_1599086_0 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 456.0
DTH2_k127_1599086_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 397.0
DTH2_k127_1599086_10 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000006484 121.0
DTH2_k127_1599086_11 to GP 1890198 percent identity - - - 0.000000000000005659 85.0
DTH2_k127_1599086_12 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000119 63.0
DTH2_k127_1599086_13 Major facilitator superfamily K08222 - - 0.00002287 56.0
DTH2_k127_1599086_2 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 375.0
DTH2_k127_1599086_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 301.0
DTH2_k127_1599086_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 258.0
DTH2_k127_1599086_5 Involved in the catabolism of quinolinic acid (QA) K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000252 260.0
DTH2_k127_1599086_6 nitrogen compound transport K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000001521 247.0
DTH2_k127_1599086_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000002927 268.0
DTH2_k127_1599086_8 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000001751 168.0
DTH2_k127_1599086_9 Biotin-protein ligase, N terminal - - - 0.00000000000000000000000000000000000000000001809 176.0
DTH2_k127_1656781_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 439.0
DTH2_k127_1656781_1 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 371.0
DTH2_k127_1656781_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009989 273.0
DTH2_k127_1656781_3 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000143 209.0
DTH2_k127_1656781_4 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000001072 196.0
DTH2_k127_1656781_5 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000002597 172.0
DTH2_k127_1656781_6 Magnesium transport protein CorA K03284 - - 0.000000000000000000000000008642 121.0
DTH2_k127_1656781_7 SMART regulatory protein, Crp K07730 - - 0.00000000000000002013 92.0
DTH2_k127_1656781_8 Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo K01766,K11717 GO:0001887,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009000,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0019538,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031162,GO:0031163,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564 2.8.1.7,4.4.1.16 0.000000000008076 73.0
DTH2_k127_1741916_0 Glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 603.0
DTH2_k127_1741916_1 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 386.0
DTH2_k127_1741916_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000003433 213.0
DTH2_k127_1741916_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000003436 132.0
DTH2_k127_1741916_4 Major Facilitator Superfamily - - - 0.00000000000000000000000002596 119.0
DTH2_k127_1984738_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 401.0
DTH2_k127_1984738_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 345.0
DTH2_k127_1997297_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 515.0
DTH2_k127_1997297_1 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000004068 196.0
DTH2_k127_1997297_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000003595 190.0
DTH2_k127_1997297_3 KaiC - - - 0.00000000000000000000000000000000000001565 158.0
DTH2_k127_1997297_4 KaiC - - - 0.00000000000000000000000000008483 126.0
DTH2_k127_1997297_5 helix_turn_helix ASNC type K06154 - - 0.00000000000000000000000004109 112.0
DTH2_k127_1997297_6 - - - - 0.00000000001978 72.0
DTH2_k127_1997297_7 EamA-like transporter family - - - 0.000007692 57.0
DTH2_k127_1997297_8 Protein of unknown function (DUF835) - - - 0.00002597 51.0
DTH2_k127_2115830_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1051.0
DTH2_k127_2115830_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 602.0
DTH2_k127_2115830_10 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0000000000000000000002508 104.0
DTH2_k127_2115830_11 - - - - 0.000001407 53.0
DTH2_k127_2115830_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00001483 47.0
DTH2_k127_2115830_2 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 319.0
DTH2_k127_2115830_3 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001025 235.0
DTH2_k127_2115830_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000002467 239.0
DTH2_k127_2115830_5 nitroreductase - - - 0.0000000000000000000000000000000000000000000000007828 180.0
DTH2_k127_2115830_6 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000006534 167.0
DTH2_k127_2115830_7 EamA-like transporter family - - - 0.00000000000000000000000000000000003931 145.0
DTH2_k127_2115830_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000003096 134.0
DTH2_k127_2115830_9 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000007537 115.0
DTH2_k127_2124238_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1525.0
DTH2_k127_2124238_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.365e-308 977.0
DTH2_k127_2124238_10 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 314.0
DTH2_k127_2124238_11 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 283.0
DTH2_k127_2124238_12 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000635 286.0
DTH2_k127_2124238_13 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001788 271.0
DTH2_k127_2124238_14 TatD related DNase K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002144 274.0
DTH2_k127_2124238_15 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000398 276.0
DTH2_k127_2124238_16 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000009125 212.0
DTH2_k127_2124238_17 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000001221 209.0
DTH2_k127_2124238_18 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001522 204.0
DTH2_k127_2124238_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000009562 198.0
DTH2_k127_2124238_2 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 572.0
DTH2_k127_2124238_20 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000009439 196.0
DTH2_k127_2124238_21 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000002544 158.0
DTH2_k127_2124238_22 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000008649 158.0
DTH2_k127_2124238_23 Peptidase family M28 K01439 - 3.5.1.18 0.000000000000000000000000000000000000001291 161.0
DTH2_k127_2124238_24 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000006439 107.0
DTH2_k127_2124238_25 PFAM Peptidase C11, clostripain - - - 0.00000000000000000000000567 115.0
DTH2_k127_2124238_26 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000004937 101.0
DTH2_k127_2124238_27 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000001718 101.0
DTH2_k127_2124238_28 Ribbon-helix-helix protein, copG family K07722 - - 0.000000000000000000002517 100.0
DTH2_k127_2124238_29 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000001408 90.0
DTH2_k127_2124238_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 528.0
DTH2_k127_2124238_30 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000007569 83.0
DTH2_k127_2124238_31 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000000000002716 81.0
DTH2_k127_2124238_32 - - - - 0.000000000000001682 77.0
DTH2_k127_2124238_33 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000001609 71.0
DTH2_k127_2124238_34 - - - - 0.000000000002673 76.0
DTH2_k127_2124238_35 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 - - - 0.000000001388 68.0
DTH2_k127_2124238_36 PFAM M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.00000001532 59.0
DTH2_k127_2124238_37 FMN binding - - - 0.00002238 53.0
DTH2_k127_2124238_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 473.0
DTH2_k127_2124238_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 471.0
DTH2_k127_2124238_6 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 466.0
DTH2_k127_2124238_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 338.0
DTH2_k127_2124238_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 325.0
DTH2_k127_2124238_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 317.0
DTH2_k127_2151549_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 483.0
DTH2_k127_2151549_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 466.0
DTH2_k127_2151549_2 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 325.0
DTH2_k127_2151549_3 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000001773 235.0
DTH2_k127_2151549_4 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000447 97.0
DTH2_k127_2151549_5 - - - - 0.000000000005866 69.0
DTH2_k127_2254260_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1025.0
DTH2_k127_2254260_1 KH domain K07041 - - 2.666e-270 844.0
DTH2_k127_2254260_10 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 397.0
DTH2_k127_2254260_11 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 375.0
DTH2_k127_2254260_12 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 336.0
DTH2_k127_2254260_13 Diacylglycerol kinase catalytic domain K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 306.0
DTH2_k127_2254260_14 Type II/IV secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 305.0
DTH2_k127_2254260_15 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000098 250.0
DTH2_k127_2254260_16 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000000000006662 246.0
DTH2_k127_2254260_17 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000001545 241.0
DTH2_k127_2254260_18 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000003884 212.0
DTH2_k127_2254260_19 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
DTH2_k127_2254260_2 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 5.73e-228 718.0
DTH2_k127_2254260_20 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000005858 201.0
DTH2_k127_2254260_21 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.0000000000000000000000000000000000000000000000000000006423 199.0
DTH2_k127_2254260_22 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000009704 193.0
DTH2_k127_2254260_23 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000006317 176.0
DTH2_k127_2254260_24 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000002685 166.0
DTH2_k127_2254260_25 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000345 170.0
DTH2_k127_2254260_26 transposase activity - - - 0.00000000000000000000000000000000000001386 158.0
DTH2_k127_2254260_27 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000222 133.0
DTH2_k127_2254260_28 Major Facilitator Superfamily - - - 0.000000000000000000000000007271 124.0
DTH2_k127_2254260_29 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.00000000000000000000000001161 117.0
DTH2_k127_2254260_3 AAA domain K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 586.0
DTH2_k127_2254260_30 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.0000000000000000000000001262 109.0
DTH2_k127_2254260_31 - - - - 0.00000000000000000000000427 106.0
DTH2_k127_2254260_32 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000004796 110.0
DTH2_k127_2254260_33 exosome subunit K07581 - - 0.00000000000000000000001513 106.0
DTH2_k127_2254260_34 PAS domain K02488 - 2.7.7.65 0.00000000000000000000005335 106.0
DTH2_k127_2254260_35 Belongs to the PDCD5 family K06875 - - 0.000000000000000000005159 96.0
DTH2_k127_2254260_36 Pfam:DUF59 - - - 0.000000000000000000005684 95.0
DTH2_k127_2254260_37 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000000001298 88.0
DTH2_k127_2254260_38 - - - - 0.000000000000000005906 98.0
DTH2_k127_2254260_39 PFAM Response regulator receiver domain K03413 - - 0.00000000000000001749 86.0
DTH2_k127_2254260_4 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 477.0
DTH2_k127_2254260_40 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000003656 73.0
DTH2_k127_2254260_41 transposase activity - - - 0.000003068 51.0
DTH2_k127_2254260_42 cheY-homologous receiver domain - - - 0.00005962 56.0
DTH2_k127_2254260_43 ThiS family K03154 - - 0.0005006 48.0
DTH2_k127_2254260_5 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 475.0
DTH2_k127_2254260_6 Toprim domain K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 441.0
DTH2_k127_2254260_7 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 417.0
DTH2_k127_2254260_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 390.0
DTH2_k127_2254260_9 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 371.0
DTH2_k127_2583757_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 448.0
DTH2_k127_2583757_1 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 293.0
DTH2_k127_2583757_2 Integrase - - - 0.0000000000000000000000000000000000000000000000004163 179.0
DTH2_k127_2602107_0 Radical SAM domain protein K09711 - - 0.00000000000000000000000001428 114.0
DTH2_k127_2602107_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0003718 44.0
DTH2_k127_2611101_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 498.0
DTH2_k127_2611101_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 493.0
DTH2_k127_2611101_10 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000383 182.0
DTH2_k127_2611101_11 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000009379 137.0
DTH2_k127_2611101_12 EamA-like transporter family - - - 0.000000000000000000000000005428 122.0
DTH2_k127_2611101_13 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.000000000000000000009167 95.0
DTH2_k127_2611101_14 - - - - 0.0000000000000000001984 91.0
DTH2_k127_2611101_15 Belongs to the UPF0434 family - - - 0.000000000000000000666 87.0
DTH2_k127_2611101_16 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000001324 95.0
DTH2_k127_2611101_17 amine dehydrogenase activity - - - 0.0000000000000001366 85.0
DTH2_k127_2611101_18 Circadian clock protein KaiC - - - 0.0000000001515 71.0
DTH2_k127_2611101_19 RHS Repeat - - - 0.0000000005313 69.0
DTH2_k127_2611101_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 428.0
DTH2_k127_2611101_20 Protein of unknown function (DUF420) K08976 - - 0.00001744 53.0
DTH2_k127_2611101_21 Acetyltransferase (GNAT) domain - - - 0.00003617 53.0
DTH2_k127_2611101_22 integral membrane protein - - - 0.0004353 51.0
DTH2_k127_2611101_23 membrane - - - 0.0005947 49.0
DTH2_k127_2611101_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 394.0
DTH2_k127_2611101_4 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 292.0
DTH2_k127_2611101_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004507 288.0
DTH2_k127_2611101_6 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005542 277.0
DTH2_k127_2611101_7 Subtilase family K13274,K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001457 264.0
DTH2_k127_2611101_8 Iron permease FTR1 K07243 - - 0.0000000000000000000000000000000000000000000000000000000001763 213.0
DTH2_k127_2611101_9 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000000000000000000000000009827 188.0
DTH2_k127_2654956_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 466.0
DTH2_k127_2654956_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 352.0
DTH2_k127_2654956_2 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
DTH2_k127_2654956_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 299.0
DTH2_k127_2654956_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 305.0
DTH2_k127_2654956_5 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000001212 232.0
DTH2_k127_2654956_6 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.0000000000000000000000000000000000000000000002905 179.0
DTH2_k127_2654956_7 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000001413 158.0
DTH2_k127_2654956_8 ribosomal small subunit binding - - - 0.000008291 56.0
DTH2_k127_2657902_0 Heat shock 70 kDa protein K04043 - - 1.556e-273 854.0
DTH2_k127_2657902_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 2.149e-234 737.0
DTH2_k127_2657902_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 381.0
DTH2_k127_2657902_11 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 370.0
DTH2_k127_2657902_12 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 365.0
DTH2_k127_2657902_13 SMART Elongator protein 3 MiaB NifB K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 347.0
DTH2_k127_2657902_14 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 343.0
DTH2_k127_2657902_15 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 322.0
DTH2_k127_2657902_16 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 297.0
DTH2_k127_2657902_17 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000001892 269.0
DTH2_k127_2657902_18 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 270.0
DTH2_k127_2657902_19 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000001044 248.0
DTH2_k127_2657902_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 8.044e-200 638.0
DTH2_k127_2657902_20 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000003699 246.0
DTH2_k127_2657902_21 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000005122 241.0
DTH2_k127_2657902_22 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000006313 239.0
DTH2_k127_2657902_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000125 239.0
DTH2_k127_2657902_24 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000002376 226.0
DTH2_k127_2657902_25 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000001065 210.0
DTH2_k127_2657902_26 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000006666 204.0
DTH2_k127_2657902_27 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000006051 195.0
DTH2_k127_2657902_28 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000002819 194.0
DTH2_k127_2657902_29 - - - - 0.00000000000000000000000000000000000000001216 164.0
DTH2_k127_2657902_3 helicase superfamily c-terminal domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 571.0
DTH2_k127_2657902_30 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000002306 148.0
DTH2_k127_2657902_31 Helix-turn-helix XRE-family like proteins K03627 - - 0.00000000000000000000000000000004972 131.0
DTH2_k127_2657902_32 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000002058 129.0
DTH2_k127_2657902_33 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.000000000000000000000000000004259 130.0
DTH2_k127_2657902_34 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000005181 106.0
DTH2_k127_2657902_35 protein conserved in archaea - - - 0.00000000000000000001396 100.0
DTH2_k127_2657902_36 Iron-sulphur cluster biosynthesis K15724 - - 0.000000000000000901 84.0
DTH2_k127_2657902_37 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000001948 77.0
DTH2_k127_2657902_38 - - - - 0.000000007267 59.0
DTH2_k127_2657902_39 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0001017 52.0
DTH2_k127_2657902_4 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 523.0
DTH2_k127_2657902_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 481.0
DTH2_k127_2657902_6 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 442.0
DTH2_k127_2657902_7 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 428.0
DTH2_k127_2657902_8 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 405.0
DTH2_k127_2657902_9 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
DTH2_k127_2682001_0 Glycerol dehydrogenase K00005,K00096 - 1.1.1.261,1.1.1.6 0.00000000000000000000000000000000002158 142.0
DTH2_k127_2682001_1 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000002347 147.0
DTH2_k127_2727672_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1110.0
DTH2_k127_2727672_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1079.0
DTH2_k127_2727672_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 355.0
DTH2_k127_2727672_11 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008819 284.0
DTH2_k127_2727672_12 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001065 239.0
DTH2_k127_2727672_13 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004474 232.0
DTH2_k127_2727672_14 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000006387 228.0
DTH2_k127_2727672_15 Acetamidase formamidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000001596 229.0
DTH2_k127_2727672_16 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000015 218.0
DTH2_k127_2727672_17 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000002054 192.0
DTH2_k127_2727672_18 - - - - 0.0000000000000000000000000000000000003586 148.0
DTH2_k127_2727672_19 spore germination K03605 - - 0.000000000000000000000000000001845 126.0
DTH2_k127_2727672_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.204e-270 847.0
DTH2_k127_2727672_20 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000153 124.0
DTH2_k127_2727672_21 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000003002 118.0
DTH2_k127_2727672_22 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000006787 98.0
DTH2_k127_2727672_23 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000736 88.0
DTH2_k127_2727672_24 Transcriptional regulator K07722 - - 0.000000000000001249 84.0
DTH2_k127_2727672_25 - - - - 0.000000000000001849 85.0
DTH2_k127_2727672_26 Belongs to the UPF0216 family K09737 - - 0.000000000756 68.0
DTH2_k127_2727672_27 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000008594 73.0
DTH2_k127_2727672_28 DNA polymerase alpha chain like domain - - - 0.000001013 52.0
DTH2_k127_2727672_29 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000001692 56.0
DTH2_k127_2727672_3 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 601.0
DTH2_k127_2727672_4 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 529.0
DTH2_k127_2727672_5 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 484.0
DTH2_k127_2727672_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 459.0
DTH2_k127_2727672_7 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 411.0
DTH2_k127_2727672_8 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 409.0
DTH2_k127_2727672_9 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 350.0
DTH2_k127_278872_0 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000003545 228.0
DTH2_k127_278872_1 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000001598 189.0
DTH2_k127_2824421_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 6.047e-231 727.0
DTH2_k127_2824421_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 527.0
DTH2_k127_2824421_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 447.0
DTH2_k127_2824421_3 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 408.0
DTH2_k127_2824421_4 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 318.0
DTH2_k127_2824421_5 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004693 278.0
DTH2_k127_2824421_6 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003014 229.0
DTH2_k127_2824421_7 - - - - 0.000000000000000000000000001589 119.0
DTH2_k127_2824421_8 OsmC-like protein - - - 0.0000000000000000003478 89.0
DTH2_k127_2824421_9 - - - - 0.0000000000000002072 83.0
DTH2_k127_2839961_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 6.034e-255 798.0
DTH2_k127_2839961_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.919e-240 747.0
DTH2_k127_2839961_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007283 285.0
DTH2_k127_2839961_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004252 260.0
DTH2_k127_2839961_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000003767 242.0
DTH2_k127_2839961_13 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000001416 186.0
DTH2_k127_2839961_14 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000006826 166.0
DTH2_k127_2839961_15 Radical SAM domain protein K09711 - - 0.0000000000000000000000000000000000004904 145.0
DTH2_k127_2839961_16 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000001055 148.0
DTH2_k127_2839961_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000001062 103.0
DTH2_k127_2839961_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000002191 100.0
DTH2_k127_2839961_19 Belongs to the UPF0200 family - - - 0.00000000000000000007659 97.0
DTH2_k127_2839961_2 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 479.0
DTH2_k127_2839961_20 ATP synthase subunit C K02124 - - 0.0000000000000002846 81.0
DTH2_k127_2839961_21 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000002722 80.0
DTH2_k127_2839961_22 membrane-associated protein domain - - - 0.0000004715 59.0
DTH2_k127_2839961_23 CAAX protease self-immunity - - - 0.0001502 50.0
DTH2_k127_2839961_24 PFAM Ribosomal LX protein K02944 - - 0.000228 46.0
DTH2_k127_2839961_25 Protein of unknown function (DUF3198) - - - 0.0009272 47.0
DTH2_k127_2839961_3 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 471.0
DTH2_k127_2839961_4 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 437.0
DTH2_k127_2839961_5 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 428.0
DTH2_k127_2839961_6 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 391.0
DTH2_k127_2839961_7 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 371.0
DTH2_k127_2839961_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 340.0
DTH2_k127_2839961_9 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 327.0
DTH2_k127_2966328_0 DEAD/H associated K03724 - - 9.046e-308 969.0
DTH2_k127_2966328_1 Type II/IV secretion system protein K07332 - - 4.327e-222 702.0
DTH2_k127_2966328_10 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 340.0
DTH2_k127_2966328_11 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 316.0
DTH2_k127_2966328_12 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 294.0
DTH2_k127_2966328_13 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001234 261.0
DTH2_k127_2966328_14 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000039 244.0
DTH2_k127_2966328_15 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000009584 217.0
DTH2_k127_2966328_16 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000001762 213.0
DTH2_k127_2966328_17 Protein of unknown function (DUF531) K09725 - - 0.000000000000000000000000000000000000000000000000000003944 195.0
DTH2_k127_2966328_18 Sodium hydrogen exchanger K11105 - - 0.000000000000000000000000000000000000000000000006734 189.0
DTH2_k127_2966328_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000799 163.0
DTH2_k127_2966328_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 626.0
DTH2_k127_2966328_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000001201 125.0
DTH2_k127_2966328_21 - - - - 0.00000000000000000000000000001366 130.0
DTH2_k127_2966328_22 - - - - 0.00000000000000000000005303 103.0
DTH2_k127_2966328_23 - K00960 - 2.7.7.6 0.000000000000001567 79.0
DTH2_k127_2966328_24 PFAM PKD domain containing protein - - - 0.000000000004067 77.0
DTH2_k127_2966328_25 - - - - 0.0002896 45.0
DTH2_k127_2966328_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 536.0
DTH2_k127_2966328_4 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 484.0
DTH2_k127_2966328_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 472.0
DTH2_k127_2966328_6 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 412.0
DTH2_k127_2966328_7 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 396.0
DTH2_k127_2966328_8 Belongs to the arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 370.0
DTH2_k127_2966328_9 Thioredoxin domain K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 353.0
DTH2_k127_3054993_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 524.0
DTH2_k127_3054993_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 334.0
DTH2_k127_3054993_10 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000003635 163.0
DTH2_k127_3054993_11 Response regulator receiver domain K03413 - - 0.00000000000000000000001185 104.0
DTH2_k127_3054993_12 Acetyltransferase (GNAT) domain - - - 0.0000000000004144 79.0
DTH2_k127_3054993_13 but it may be involved in stabilization of the trimeric complex - - - 0.00000000004805 64.0
DTH2_k127_3054993_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 335.0
DTH2_k127_3054993_3 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005325 273.0
DTH2_k127_3054993_4 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000001248 229.0
DTH2_k127_3054993_5 DNA polymerase alpha chain like domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000001039 213.0
DTH2_k127_3054993_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000002113 208.0
DTH2_k127_3054993_7 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000001379 203.0
DTH2_k127_3054993_8 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000005057 204.0
DTH2_k127_3054993_9 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000001835 195.0
DTH2_k127_311438_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 602.0
DTH2_k127_311438_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 355.0
DTH2_k127_311438_2 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000003653 257.0
DTH2_k127_311438_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
DTH2_k127_311438_4 Protein of unknown function TPD sequence-motif - - - 0.000000000000000000000000000000000000000000000000000000000003851 217.0
DTH2_k127_3135917_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1.638e-320 994.0
DTH2_k127_3135917_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 584.0
DTH2_k127_3135917_10 Pantothenate synthetase K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000000001241 259.0
DTH2_k127_3135917_11 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001366 260.0
DTH2_k127_3135917_12 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
DTH2_k127_3135917_13 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000002073 240.0
DTH2_k127_3135917_14 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000009777 242.0
DTH2_k127_3135917_15 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000007184 207.0
DTH2_k127_3135917_16 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000008126 182.0
DTH2_k127_3135917_17 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000000000000000002314 188.0
DTH2_k127_3135917_18 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000000004727 175.0
DTH2_k127_3135917_19 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000006127 158.0
DTH2_k127_3135917_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 514.0
DTH2_k127_3135917_20 GvpD gas vesicle protein - - - 0.000000000000000000000000000000000000006738 153.0
DTH2_k127_3135917_21 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.00000000000000000000000000000000001137 150.0
DTH2_k127_3135917_22 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000005434 137.0
DTH2_k127_3135917_23 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001964 130.0
DTH2_k127_3135917_24 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000000004977 126.0
DTH2_k127_3135917_25 - - - - 0.000000000000000000000000001538 124.0
DTH2_k127_3135917_26 - - - - 0.00000000000000000000000009622 114.0
DTH2_k127_3135917_27 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000001197 102.0
DTH2_k127_3135917_28 cheY-homologous receiver domain - - - 0.000000000000000000007119 98.0
DTH2_k127_3135917_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000004804 96.0
DTH2_k127_3135917_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 512.0
DTH2_k127_3135917_30 Major Facilitator K08151,K08153 - - 0.0000000000000002275 92.0
DTH2_k127_3135917_31 - - - - 0.00000000000003338 76.0
DTH2_k127_3135917_32 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000003275 76.0
DTH2_k127_3135917_33 Protein of unknown function DUF131 - - - 0.00000002337 61.0
DTH2_k127_3135917_34 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000007967 62.0
DTH2_k127_3135917_35 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000003015 61.0
DTH2_k127_3135917_36 H ACA RNA-protein complex K07569 - - 0.00002795 50.0
DTH2_k127_3135917_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 444.0
DTH2_k127_3135917_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 425.0
DTH2_k127_3135917_6 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
DTH2_k127_3135917_7 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 294.0
DTH2_k127_3135917_8 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002139 287.0
DTH2_k127_3135917_9 PFAM sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000841 271.0
DTH2_k127_3279472_0 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000000000000000855 160.0
DTH2_k127_3279472_1 Integral membrane protein DUF92 - - - 0.000000000000000000000000000004366 130.0
DTH2_k127_3279472_2 OmpA family K02557,K03286 - - 0.000007211 52.0
DTH2_k127_3306333_0 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000002227 206.0
DTH2_k127_3470374_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1299.0
DTH2_k127_3470374_1 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 9.98e-245 831.0
DTH2_k127_3470374_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
DTH2_k127_3470374_11 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000000000000000000000000002628 214.0
DTH2_k127_3470374_12 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000001086 173.0
DTH2_k127_3470374_13 Methyltransferase domain K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000117 149.0
DTH2_k127_3470374_14 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000006644 143.0
DTH2_k127_3470374_15 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000002828 126.0
DTH2_k127_3470374_16 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000002424 127.0
DTH2_k127_3470374_17 TraB family - - - 0.0000000000000000000000000006977 122.0
DTH2_k127_3470374_18 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.00000000000000000000000002143 117.0
DTH2_k127_3470374_19 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000001416 91.0
DTH2_k127_3470374_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 596.0
DTH2_k127_3470374_20 Rhomboid family - - - 0.000000000000004872 85.0
DTH2_k127_3470374_21 CARDB - - - 0.0000000000000614 83.0
DTH2_k127_3470374_22 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000001391 55.0
DTH2_k127_3470374_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 471.0
DTH2_k127_3470374_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 449.0
DTH2_k127_3470374_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 423.0
DTH2_k127_3470374_6 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 372.0
DTH2_k127_3470374_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 293.0
DTH2_k127_3470374_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 280.0
DTH2_k127_3470374_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001272 250.0
DTH2_k127_3602595_0 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 306.0
DTH2_k127_3602595_1 B12 binding domain - - - 0.000003138 50.0
DTH2_k127_3602595_2 Double zinc ribbon and ankyrin - - - 0.0002329 50.0
DTH2_k127_371307_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 535.0
DTH2_k127_371307_1 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 290.0
DTH2_k127_371307_2 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001543 260.0
DTH2_k127_371307_3 archaeal coiled-coil protein - - - 0.000000000000000000000000001619 123.0
DTH2_k127_371307_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000001734 97.0
DTH2_k127_371307_5 PFAM Tetratricopeptide repeat - - - 0.00000000000000006697 95.0
DTH2_k127_371307_6 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000002195 72.0
DTH2_k127_371307_7 Lamin Tail Domain - - - 0.00002026 58.0
DTH2_k127_371307_8 Participates in both transcription termination and antitermination K02600 - - 0.0003556 52.0
DTH2_k127_371307_9 MacB-like periplasmic core domain - - - 0.0009868 47.0
DTH2_k127_3738931_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1048.0
DTH2_k127_3738931_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.205e-284 892.0
DTH2_k127_3738931_10 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 431.0
DTH2_k127_3738931_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 389.0
DTH2_k127_3738931_12 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 383.0
DTH2_k127_3738931_13 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 347.0
DTH2_k127_3738931_14 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 349.0
DTH2_k127_3738931_15 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 355.0
DTH2_k127_3738931_16 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 329.0
DTH2_k127_3738931_17 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006552 275.0
DTH2_k127_3738931_18 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
DTH2_k127_3738931_19 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 272.0
DTH2_k127_3738931_2 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 4.716e-214 679.0
DTH2_k127_3738931_20 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000006871 267.0
DTH2_k127_3738931_21 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003287 269.0
DTH2_k127_3738931_22 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000301 264.0
DTH2_k127_3738931_23 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000001089 230.0
DTH2_k127_3738931_24 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000000000000000000000004285 216.0
DTH2_k127_3738931_25 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000002925 217.0
DTH2_k127_3738931_26 and related - - - 0.000000000000000000000000000000000000000000000000000000008527 209.0
DTH2_k127_3738931_27 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000001357 207.0
DTH2_k127_3738931_28 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000008971 204.0
DTH2_k127_3738931_29 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000008151 194.0
DTH2_k127_3738931_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 8.499e-199 629.0
DTH2_k127_3738931_30 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000001254 194.0
DTH2_k127_3738931_31 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000006852 197.0
DTH2_k127_3738931_32 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000008624 174.0
DTH2_k127_3738931_33 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000121 169.0
DTH2_k127_3738931_34 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000000000001747 165.0
DTH2_k127_3738931_35 - - - - 0.0000000000000000000000000000000000000000001982 162.0
DTH2_k127_3738931_36 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000002334 167.0
DTH2_k127_3738931_37 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000006594 162.0
DTH2_k127_3738931_38 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000782 146.0
DTH2_k127_3738931_39 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000000000003642 141.0
DTH2_k127_3738931_4 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 608.0
DTH2_k127_3738931_40 Thiamine-binding protein - - - 0.00000000000000000000000000000053 124.0
DTH2_k127_3738931_41 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000000000002914 120.0
DTH2_k127_3738931_42 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000002584 119.0
DTH2_k127_3738931_43 membrane - - - 0.0000000000000000000000000008373 121.0
DTH2_k127_3738931_44 Fcf1 K07158 - - 0.0000000000000000000000000665 110.0
DTH2_k127_3738931_45 4Fe-4S binding domain - - - 0.000000000000000000006171 98.0
DTH2_k127_3738931_46 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000818 94.0
DTH2_k127_3738931_47 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000103 97.0
DTH2_k127_3738931_48 Clostripain family - - - 0.0000000000000005126 92.0
DTH2_k127_3738931_49 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000004698 88.0
DTH2_k127_3738931_5 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 571.0
DTH2_k127_3738931_50 PFAM EamA-like transporter family - - - 0.0000000000002036 81.0
DTH2_k127_3738931_51 - - - - 0.0007585 46.0
DTH2_k127_3738931_6 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 563.0
DTH2_k127_3738931_7 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 551.0
DTH2_k127_3738931_8 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 538.0
DTH2_k127_3738931_9 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 491.0
DTH2_k127_3842181_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000001015 267.0
DTH2_k127_3842181_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000009259 56.0
DTH2_k127_3842181_2 cobalamin binding K16177 - - 0.0000005713 53.0
DTH2_k127_4059808_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 554.0
DTH2_k127_4059808_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 375.0
DTH2_k127_4059808_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000009629 233.0
DTH2_k127_4059808_11 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000321 219.0
DTH2_k127_4059808_12 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000005748 225.0
DTH2_k127_4059808_13 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000003243 209.0
DTH2_k127_4059808_14 - - - - 0.00000000000000000000000000000000000000000001328 181.0
DTH2_k127_4059808_15 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000002622 136.0
DTH2_k127_4059808_16 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000003617 132.0
DTH2_k127_4059808_17 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000000001491 124.0
DTH2_k127_4059808_18 Transcriptional regulator, TrmB - - - 0.000000000000000000000000000001516 126.0
DTH2_k127_4059808_19 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000004312 93.0
DTH2_k127_4059808_2 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 377.0
DTH2_k127_4059808_20 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000000003827 100.0
DTH2_k127_4059808_21 - - - - 0.00000000000000000005722 96.0
DTH2_k127_4059808_22 - - - - 0.0000000000000000003768 97.0
DTH2_k127_4059808_23 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000009276 95.0
DTH2_k127_4059808_24 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000000002777 80.0
DTH2_k127_4059808_26 Protein of unknown function (DUF3795) - - - 0.0000002139 57.0
DTH2_k127_4059808_27 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000001907 53.0
DTH2_k127_4059808_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 328.0
DTH2_k127_4059808_4 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 295.0
DTH2_k127_4059808_5 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008277 287.0
DTH2_k127_4059808_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000274 278.0
DTH2_k127_4059808_7 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009858 276.0
DTH2_k127_4059808_8 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000121 265.0
DTH2_k127_4059808_9 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000002462 250.0
DTH2_k127_4077155_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.00000000000001494 75.0
DTH2_k127_4077155_1 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.00000000004978 68.0
DTH2_k127_4077155_2 MacB-like periplasmic core domain K02004 - - 0.000004314 61.0
DTH2_k127_4077155_3 Transcription factor zinc-finger - - - 0.00008475 53.0
DTH2_k127_4250134_0 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000005 220.0
DTH2_k127_4250134_1 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000002005 155.0
DTH2_k127_4250134_2 - - - - 0.00003726 47.0
DTH2_k127_4258493_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 411.0
DTH2_k127_4258493_1 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 298.0
DTH2_k127_4258493_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002256 140.0
DTH2_k127_4258493_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000001061 144.0
DTH2_k127_4258493_12 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000000000001137 123.0
DTH2_k127_4258493_13 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000005643 96.0
DTH2_k127_4258493_14 ribosomal protein S14 K02954 - - 0.000000000000000000006638 92.0
DTH2_k127_4258493_15 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000094 74.0
DTH2_k127_4258493_16 Ribosomal L29 protein K02904 - - 0.000000000001838 78.0
DTH2_k127_4258493_2 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003238 273.0
DTH2_k127_4258493_3 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000007746 248.0
DTH2_k127_4258493_4 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001092 226.0
DTH2_k127_4258493_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000001456 214.0
DTH2_k127_4258493_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001081 197.0
DTH2_k127_4258493_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001121 201.0
DTH2_k127_4258493_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000001405 190.0
DTH2_k127_4258493_9 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000181 155.0
DTH2_k127_432565_0 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 348.0
DTH2_k127_432565_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004191 268.0
DTH2_k127_432565_2 ACT domain protein - - - 0.0000000000001447 75.0
DTH2_k127_432565_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000001741 63.0
DTH2_k127_432565_4 Alginate lyase - - - 0.00000002196 64.0
DTH2_k127_432565_5 Acetyltransferase (GNAT) family - - - 0.00000016 61.0
DTH2_k127_432565_6 virion core protein, lumpy skin disease virus - - - 0.000005076 51.0
DTH2_k127_4440728_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 513.0
DTH2_k127_4440728_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 389.0
DTH2_k127_4440728_2 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
DTH2_k127_4440728_3 CO dehydrogenase acetyl-CoA synthase K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000001936 232.0
DTH2_k127_4440728_4 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000007421 195.0
DTH2_k127_4440728_5 - - - - 0.0000000000000000000000000000000000003679 144.0
DTH2_k127_4440728_6 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000004542 136.0
DTH2_k127_4440728_7 Clostripain family - - - 0.0000000000000000000000000000002568 138.0
DTH2_k127_4440728_8 PFAM amino acid-binding ACT domain protein - - - 0.0001579 50.0
DTH2_k127_5078451_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 6.62e-254 801.0
DTH2_k127_5078451_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.497e-221 702.0
DTH2_k127_5078451_10 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 388.0
DTH2_k127_5078451_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 374.0
DTH2_k127_5078451_12 ABC transporter, ATP-binding protein K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 372.0
DTH2_k127_5078451_13 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 362.0
DTH2_k127_5078451_14 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 355.0
DTH2_k127_5078451_15 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 335.0
DTH2_k127_5078451_16 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 319.0
DTH2_k127_5078451_17 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 309.0
DTH2_k127_5078451_18 Major facilitator superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009751 305.0
DTH2_k127_5078451_19 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 293.0
DTH2_k127_5078451_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.087e-220 700.0
DTH2_k127_5078451_20 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 294.0
DTH2_k127_5078451_21 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005986 278.0
DTH2_k127_5078451_22 ABC-type dipeptide oligopeptide nickel transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000156 270.0
DTH2_k127_5078451_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002145 269.0
DTH2_k127_5078451_24 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001602 248.0
DTH2_k127_5078451_25 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000001647 238.0
DTH2_k127_5078451_26 Family 5 K02035,K13889 - - 0.000000000000000000000000000000000000000000000000000000000000000000191 251.0
DTH2_k127_5078451_27 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000001851 234.0
DTH2_k127_5078451_28 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000003496 226.0
DTH2_k127_5078451_29 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000004502 231.0
DTH2_k127_5078451_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341,K22167 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 596.0
DTH2_k127_5078451_30 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000005846 216.0
DTH2_k127_5078451_31 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000009846 214.0
DTH2_k127_5078451_32 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000000000678 198.0
DTH2_k127_5078451_33 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000001258 194.0
DTH2_k127_5078451_34 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000000000002596 176.0
DTH2_k127_5078451_35 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.0000000000000000000000000000000000000000000003301 170.0
DTH2_k127_5078451_36 Rubrerythrin - - - 0.00000000000000000000000000000000000000000001253 170.0
DTH2_k127_5078451_37 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000000436 160.0
DTH2_k127_5078451_38 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000009944 164.0
DTH2_k127_5078451_39 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000003655 146.0
DTH2_k127_5078451_4 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 509.0
DTH2_k127_5078451_40 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001905 144.0
DTH2_k127_5078451_41 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.000000000000000000000000000000006414 143.0
DTH2_k127_5078451_42 PHP-associated - - - 0.000000000000000000000000000000007002 136.0
DTH2_k127_5078451_43 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000002196 130.0
DTH2_k127_5078451_44 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000576 125.0
DTH2_k127_5078451_45 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000003679 124.0
DTH2_k127_5078451_46 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.000000000000000000000000001262 116.0
DTH2_k127_5078451_47 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000001332 122.0
DTH2_k127_5078451_48 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340 - 1.6.5.3 0.000000000000000000000000001525 117.0
DTH2_k127_5078451_49 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000002529 119.0
DTH2_k127_5078451_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 504.0
DTH2_k127_5078451_50 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000001536 113.0
DTH2_k127_5078451_51 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000001102 92.0
DTH2_k127_5078451_52 Right handed beta helix region - - - 0.00000000000000001316 91.0
DTH2_k127_5078451_53 Protein of unknown function (DUF2797) - - - 0.000000000000005609 85.0
DTH2_k127_5078451_54 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000007078 77.0
DTH2_k127_5078451_55 - - - - 0.00000000002359 68.0
DTH2_k127_5078451_56 Rubrerythrin - - - 0.0000000001178 68.0
DTH2_k127_5078451_57 RING finger domain protein K10631 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0016925,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019789,GO:0019941,GO:0030163,GO:0032446,GO:0036211,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0051603,GO:0061630,GO:0061659,GO:0061665,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.27 0.0001411 45.0
DTH2_k127_5078451_6 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 461.0
DTH2_k127_5078451_7 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 424.0
DTH2_k127_5078451_8 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 400.0
DTH2_k127_5078451_9 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 388.0
DTH2_k127_5078956_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 450.0
DTH2_k127_5078956_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 407.0
DTH2_k127_5078956_10 TIGRFAM segregation and condensation protein B K06024 - - 0.00000000000000000000000000000000358 134.0
DTH2_k127_5078956_11 snRNP Sm proteins K04796 - - 0.00000000000000000002527 91.0
DTH2_k127_5078956_2 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 344.0
DTH2_k127_5078956_3 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001644 287.0
DTH2_k127_5078956_4 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001065 267.0
DTH2_k127_5078956_5 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 255.0
DTH2_k127_5078956_6 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000001088 210.0
DTH2_k127_5078956_7 MobA-like NTP transferase domain K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000008148 214.0
DTH2_k127_5078956_8 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000000000000004707 204.0
DTH2_k127_5078956_9 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000001844 176.0
DTH2_k127_5160245_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 467.0
DTH2_k127_5160245_1 PFAM 4Fe-4S binding domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007717 248.0
DTH2_k127_5160245_2 DMSO reductase anchor subunit (DmsC) - - - 0.000000000000000000000000000004352 131.0
DTH2_k127_5214446_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 1.957e-233 741.0
DTH2_k127_5214446_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 536.0
DTH2_k127_5214446_10 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.000003005 54.0
DTH2_k127_5214446_11 PFAM ABC transporter K01990 - - 0.0001843 46.0
DTH2_k127_5214446_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 544.0
DTH2_k127_5214446_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
DTH2_k127_5214446_4 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000000000000000000000000000000002446 256.0
DTH2_k127_5214446_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000001225 198.0
DTH2_k127_5214446_6 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000004376 159.0
DTH2_k127_5214446_7 Group 1 family - - - 0.00000000000000000000000000000000000000494 159.0
DTH2_k127_5214446_8 Nitroreductase family - - - 0.00000000000000000000000000000000002859 141.0
DTH2_k127_5214446_9 membrane transporter protein K07090 - - 0.00000000004234 74.0
DTH2_k127_5380217_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 425.0
DTH2_k127_5380217_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001444 264.0
DTH2_k127_5380217_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000003789 178.0
DTH2_k127_5380217_3 Ferritin-like domain - - - 0.000001737 56.0
DTH2_k127_5426338_0 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 290.0
DTH2_k127_5426338_1 - - - - 0.00000000000000000000000000000000009284 139.0
DTH2_k127_5537894_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.88e-197 629.0
DTH2_k127_5537894_1 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 432.0
DTH2_k127_5537894_10 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 307.0
DTH2_k127_5537894_11 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 307.0
DTH2_k127_5537894_12 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 301.0
DTH2_k127_5537894_13 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 292.0
DTH2_k127_5537894_14 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000265 293.0
DTH2_k127_5537894_15 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
DTH2_k127_5537894_16 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007781 268.0
DTH2_k127_5537894_17 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002136 269.0
DTH2_k127_5537894_18 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000002113 235.0
DTH2_k127_5537894_19 ICC-like phosphoesterases K06953 - - 0.000000000000000000000000000000000000000000000000000000000001136 218.0
DTH2_k127_5537894_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 415.0
DTH2_k127_5537894_20 hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000003165 217.0
DTH2_k127_5537894_21 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000004781 213.0
DTH2_k127_5537894_22 Phenazine biosynthesis protein phzf family - - - 0.000000000000000000000000000000000000000000000000000000178 205.0
DTH2_k127_5537894_23 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000005739 197.0
DTH2_k127_5537894_24 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000002173 190.0
DTH2_k127_5537894_25 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000001862 174.0
DTH2_k127_5537894_26 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000000003983 150.0
DTH2_k127_5537894_27 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000000000000003884 136.0
DTH2_k127_5537894_28 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000000000001085 129.0
DTH2_k127_5537894_29 Stage II sporulation E family protein - - - 0.0000000000000000000000002346 124.0
DTH2_k127_5537894_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 409.0
DTH2_k127_5537894_30 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000001019 98.0
DTH2_k127_5537894_31 binds to the 23S rRNA K02921 - - 0.0000000000000000007229 91.0
DTH2_k127_5537894_32 - - - - 0.000000000000008112 78.0
DTH2_k127_5537894_33 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000001241 86.0
DTH2_k127_5537894_34 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.000000000002068 68.0
DTH2_k127_5537894_35 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000003279 70.0
DTH2_k127_5537894_36 Hydrogenase maturation protease K08315 - 3.4.23.51 0.00000006044 61.0
DTH2_k127_5537894_37 Transcription factor Pcc1 K09741 - - 0.00000121 56.0
DTH2_k127_5537894_38 Double zinc ribbon - - - 0.000004507 58.0
DTH2_k127_5537894_39 - - - - 0.0000924 48.0
DTH2_k127_5537894_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 400.0
DTH2_k127_5537894_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 381.0
DTH2_k127_5537894_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 384.0
DTH2_k127_5537894_7 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 341.0
DTH2_k127_5537894_8 Nickel-dependent hydrogenase K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 344.0
DTH2_k127_5537894_9 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 327.0
DTH2_k127_5611805_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.732e-229 729.0
DTH2_k127_5611805_1 proline dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 417.0
DTH2_k127_5611805_10 ABC transporter permease K02034 - - 0.000000000000001228 91.0
DTH2_k127_5611805_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000006488 66.0
DTH2_k127_5611805_2 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 337.0
DTH2_k127_5611805_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
DTH2_k127_5611805_4 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000000000000000000000000000000006566 255.0
DTH2_k127_5611805_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000001668 201.0
DTH2_k127_5611805_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000007634 174.0
DTH2_k127_5611805_7 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000005426 165.0
DTH2_k127_5611805_8 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000343 162.0
DTH2_k127_5611805_9 - - - - 0.0000000000000007301 88.0
DTH2_k127_5720290_0 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
DTH2_k127_5720290_1 peptidase activity, acting on L-amino acid peptides K09607 - - 0.0000000000000000000000000000000000000000000000000000005224 210.0
DTH2_k127_5720290_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000005751 153.0
DTH2_k127_5720290_3 - - - - 0.00000000000000000000000000002041 125.0
DTH2_k127_5736893_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 8.267e-219 692.0
DTH2_k127_5736893_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 577.0
DTH2_k127_5736893_10 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 293.0
DTH2_k127_5736893_11 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 290.0
DTH2_k127_5736893_12 oxidoreductase activity K03924,K04748,K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002157 276.0
DTH2_k127_5736893_13 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004074 259.0
DTH2_k127_5736893_14 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000008592 244.0
DTH2_k127_5736893_15 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000377 226.0
DTH2_k127_5736893_16 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000006092 199.0
DTH2_k127_5736893_17 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000001598 199.0
DTH2_k127_5736893_18 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000007882 183.0
DTH2_k127_5736893_19 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000001776 179.0
DTH2_k127_5736893_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 416.0
DTH2_k127_5736893_20 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000004228 156.0
DTH2_k127_5736893_21 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000002229 153.0
DTH2_k127_5736893_22 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000003349 159.0
DTH2_k127_5736893_23 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000008286 152.0
DTH2_k127_5736893_24 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000009083 132.0
DTH2_k127_5736893_25 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000002519 127.0
DTH2_k127_5736893_26 Cyclophilin-like K09143 - - 0.00000000000000000000000001325 114.0
DTH2_k127_5736893_27 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000002534 126.0
DTH2_k127_5736893_28 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000003333 99.0
DTH2_k127_5736893_29 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000006829 94.0
DTH2_k127_5736893_3 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 401.0
DTH2_k127_5736893_30 PFAM CBS domain - - - 0.00000000000000003984 89.0
DTH2_k127_5736893_31 Histidine kinase K07777,K19661,K21405 - 2.7.13.3 0.000000000000001652 91.0
DTH2_k127_5736893_32 - - - - 0.000000000000007452 75.0
DTH2_k127_5736893_33 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000001016 77.0
DTH2_k127_5736893_34 Ion channel - - - 0.00000000000001601 78.0
DTH2_k127_5736893_35 PFAM CBS domain K07182 - - 0.00000000000004108 79.0
DTH2_k127_5736893_36 Bacterio-opsin activator HTH K06930 - - 0.0000000000001016 79.0
DTH2_k127_5736893_37 PFAM CBS domain - - - 0.0000000000007132 74.0
DTH2_k127_5736893_38 Acetyltransferase (GNAT) domain - - - 0.000000000008122 72.0
DTH2_k127_5736893_39 Rubrerythrin - - - 0.00000000005968 71.0
DTH2_k127_5736893_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 376.0
DTH2_k127_5736893_40 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.0000000000604 73.0
DTH2_k127_5736893_41 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000001041 60.0
DTH2_k127_5736893_42 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000134 55.0
DTH2_k127_5736893_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 376.0
DTH2_k127_5736893_6 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 360.0
DTH2_k127_5736893_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 335.0
DTH2_k127_5736893_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 306.0
DTH2_k127_5736893_9 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 307.0
DTH2_k127_5742830_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.342e-210 665.0
DTH2_k127_5742830_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 576.0
DTH2_k127_5742830_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001862 200.0
DTH2_k127_5742830_11 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000003383 208.0
DTH2_k127_5742830_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000004222 183.0
DTH2_k127_5742830_13 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001925 174.0
DTH2_k127_5742830_14 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000008078 181.0
DTH2_k127_5742830_15 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000239 153.0
DTH2_k127_5742830_16 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000007913 140.0
DTH2_k127_5742830_17 Transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000244 141.0
DTH2_k127_5742830_18 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000003091 146.0
DTH2_k127_5742830_19 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000007534 136.0
DTH2_k127_5742830_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 447.0
DTH2_k127_5742830_20 membrane K08971 - - 0.0000000000000000000000009249 119.0
DTH2_k127_5742830_21 Belongs to the UPF0248 family K09715 - - 0.00000000000000000000176 96.0
DTH2_k127_5742830_22 - - - - 0.00000000002973 67.0
DTH2_k127_5742830_23 EamA-like transporter family - - - 0.00000139 59.0
DTH2_k127_5742830_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 393.0
DTH2_k127_5742830_4 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 374.0
DTH2_k127_5742830_5 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 321.0
DTH2_k127_5742830_6 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 314.0
DTH2_k127_5742830_7 Phosphohydrolase K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005448 256.0
DTH2_k127_5742830_8 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000004748 245.0
DTH2_k127_5742830_9 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000003059 213.0
DTH2_k127_6238086_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001935 256.0
DTH2_k127_6238086_1 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000003606 199.0
DTH2_k127_6347177_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1057.0
DTH2_k127_6347177_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.332e-206 649.0
DTH2_k127_6347177_10 - - - - 0.000000000000000000000000000000000000000000003132 166.0
DTH2_k127_6347177_11 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000005715 175.0
DTH2_k127_6347177_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000005846 165.0
DTH2_k127_6347177_13 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000003569 162.0
DTH2_k127_6347177_14 - - - - 0.00000000000000000000000000000000000000008492 157.0
DTH2_k127_6347177_15 LemA family K03744 - - 0.0000000000000000000000000000000000001424 147.0
DTH2_k127_6347177_16 TPM domain K06872 - - 0.0000000000000000000000001004 116.0
DTH2_k127_6347177_17 Acetyltransferase - - - 0.000000000000000159 90.0
DTH2_k127_6347177_18 PQ loop repeat K15383 - - 0.0000000000000004903 80.0
DTH2_k127_6347177_19 regulatory protein, arsR K13771 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000007355 74.0
DTH2_k127_6347177_2 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 514.0
DTH2_k127_6347177_3 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 344.0
DTH2_k127_6347177_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 286.0
DTH2_k127_6347177_5 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 295.0
DTH2_k127_6347177_6 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000006241 202.0
DTH2_k127_6347177_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000001992 199.0
DTH2_k127_6347177_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000003595 173.0
DTH2_k127_6347177_9 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000821 183.0
DTH2_k127_635780_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000001499 221.0
DTH2_k127_635780_1 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000000000004983 138.0
DTH2_k127_635780_2 DNA binding protein K06930 - - 0.000000000000000000007111 101.0
DTH2_k127_635780_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000008752 65.0
DTH2_k127_645647_0 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 371.0
DTH2_k127_645647_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 331.0
DTH2_k127_645647_2 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000006112 207.0
DTH2_k127_645647_3 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000003298 162.0
DTH2_k127_645647_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000001957 102.0
DTH2_k127_645649_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 1.819e-282 886.0
DTH2_k127_645649_1 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 580.0
DTH2_k127_645649_10 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000005141 186.0
DTH2_k127_645649_11 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000003784 189.0
DTH2_k127_645649_12 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000001077 176.0
DTH2_k127_645649_13 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000001007 159.0
DTH2_k127_645649_14 NMT1-like family K02051 - - 0.0000000000000000000000000000000000506 149.0
DTH2_k127_645649_15 Thioredoxin K03671 - - 0.0000000000000000000000000000000002799 136.0
DTH2_k127_645649_16 - - - - 0.00000000000000000000000000000006247 144.0
DTH2_k127_645649_17 PRC-barrel domain - - - 0.00000000000000000000000001645 111.0
DTH2_k127_645649_18 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000004835 101.0
DTH2_k127_645649_19 response to oxidative stress K04063 - - 0.000000000000000001146 91.0
DTH2_k127_645649_2 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 360.0
DTH2_k127_645649_20 PRC-barrel domain - - - 0.000000000000000009174 87.0
DTH2_k127_645649_21 Tetratricopeptide repeat - - - 0.00000000000000001065 98.0
DTH2_k127_645649_22 - - - - 0.0000000000004906 74.0
DTH2_k127_645649_23 Glutamine amidotransferases class-II - - - 0.0000000000009875 80.0
DTH2_k127_645649_24 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000002418 56.0
DTH2_k127_645649_25 Glycosyl transferase family 41 - - - 0.0000007814 62.0
DTH2_k127_645649_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 323.0
DTH2_k127_645649_4 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 319.0
DTH2_k127_645649_5 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008277 258.0
DTH2_k127_645649_6 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000517 237.0
DTH2_k127_645649_7 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.00000000000000000000000000000000000000000000000000000000007627 209.0
DTH2_k127_645649_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000007717 231.0
DTH2_k127_645649_9 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000003681 210.0
DTH2_k127_6463390_0 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 306.0
DTH2_k127_6463390_1 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000001063 251.0
DTH2_k127_6463390_2 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000005968 116.0
DTH2_k127_6463390_3 Transcriptional regulator - - - 0.000000000000000335 82.0
DTH2_k127_6463390_4 - - - - 0.000000000000902 78.0
DTH2_k127_6484530_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000007451 267.0
DTH2_k127_6484530_1 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001415 207.0
DTH2_k127_6484530_2 PFAM TM2 domain containing protein - - - 0.000009353 48.0
DTH2_k127_6537595_0 PFAM Pyridoxal-dependent decarboxylase, C-terminal sheet domain K13747 - 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 334.0
DTH2_k127_6537595_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000001951 216.0
DTH2_k127_6537595_2 PFAM transposase, IS4 family protein - - - 0.0000000000000000002519 97.0
DTH2_k127_6537595_3 COG3316 Transposase and inactivated derivatives K07498 - - 0.00000000005086 69.0
DTH2_k127_6537595_4 COG3316 Transposase and inactivated derivatives K07498 - - 0.00000005178 57.0
DTH2_k127_6565783_0 GXGXG motif - - - 4.328e-232 739.0
DTH2_k127_6577773_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 568.0
DTH2_k127_6577773_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 484.0
DTH2_k127_6577773_10 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 291.0
DTH2_k127_6577773_11 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001058 296.0
DTH2_k127_6577773_12 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 277.0
DTH2_k127_6577773_13 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000146 295.0
DTH2_k127_6577773_14 Kef-type K transport K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005759 284.0
DTH2_k127_6577773_15 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003715 254.0
DTH2_k127_6577773_16 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000002898 247.0
DTH2_k127_6577773_17 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000004328 213.0
DTH2_k127_6577773_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.000000000000000000000000000000000000000000000000009089 198.0
DTH2_k127_6577773_19 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000001328 177.0
DTH2_k127_6577773_2 COG0531 Amino acid transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 407.0
DTH2_k127_6577773_20 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000004877 169.0
DTH2_k127_6577773_21 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000001229 165.0
DTH2_k127_6577773_22 shikimate kinase activity K00891 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.71 0.000000000000000000000000000000000000000001246 167.0
DTH2_k127_6577773_23 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000005974 160.0
DTH2_k127_6577773_24 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000005366 151.0
DTH2_k127_6577773_25 Belongs to the UPF0280 family K09740 - - 0.000000000000000000000000000000000003506 149.0
DTH2_k127_6577773_26 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000002344 141.0
DTH2_k127_6577773_27 flavin reductase - - - 0.0000000000000000000000000000000003789 137.0
DTH2_k127_6577773_28 PFAM NIL domain - - - 0.000000000000000000000000000000001691 133.0
DTH2_k127_6577773_29 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000832 130.0
DTH2_k127_6577773_3 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 383.0
DTH2_k127_6577773_30 nucleotide metabolic process - - - 0.0000000000000000000000000003128 123.0
DTH2_k127_6577773_31 Leucyl aminopeptidase K19701 - 3.4.11.10,3.4.11.6 0.0000000000000000000000007246 118.0
DTH2_k127_6577773_32 OmpA family - - - 0.0000000000004653 76.0
DTH2_k127_6577773_4 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 376.0
DTH2_k127_6577773_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 374.0
DTH2_k127_6577773_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 347.0
DTH2_k127_6577773_7 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 334.0
DTH2_k127_6577773_8 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 319.0
DTH2_k127_6577773_9 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 314.0
DTH2_k127_6704220_0 arsonoacetate metabolic process K07755 - 2.1.1.137 0.000000000005515 75.0
DTH2_k127_6761881_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 443.0
DTH2_k127_6761881_1 light absorption K07255,K21700 - - 0.0000000000000000000000000000000000000000000000000007504 191.0
DTH2_k127_6761881_2 Double zinc ribbon - - - 0.000000000000000000000000000000000000000002485 179.0
DTH2_k127_6861995_0 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 353.0
DTH2_k127_6861995_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 342.0
DTH2_k127_6861995_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000003425 234.0
DTH2_k127_6861995_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000002395 210.0
DTH2_k127_6861995_4 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.000000000000000000000000000000000000009012 153.0
DTH2_k127_6861995_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000838 150.0
DTH2_k127_6861995_6 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000001407 123.0
DTH2_k127_6861995_7 TIGRFAM Small GTP-binding protein - - - 0.000000000000000000000000006127 120.0
DTH2_k127_6861995_8 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K02557,K03286 - - 0.000000000003233 75.0
DTH2_k127_6886394_0 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000009471 246.0
DTH2_k127_6886394_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000005837 222.0
DTH2_k127_6886394_2 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000000003636 115.0
DTH2_k127_6886394_3 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000004257 102.0
DTH2_k127_6938507_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1539.0
DTH2_k127_6938507_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.239e-272 863.0
DTH2_k127_6938507_10 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 297.0
DTH2_k127_6938507_11 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002016 252.0
DTH2_k127_6938507_12 PFAM ABC transporter K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001314 249.0
DTH2_k127_6938507_13 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003498 247.0
DTH2_k127_6938507_14 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000002704 231.0
DTH2_k127_6938507_15 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000003233 223.0
DTH2_k127_6938507_16 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000002386 225.0
DTH2_k127_6938507_17 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000004889 187.0
DTH2_k127_6938507_18 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000001747 194.0
DTH2_k127_6938507_19 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000006401 169.0
DTH2_k127_6938507_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.217e-265 831.0
DTH2_k127_6938507_20 ABC-type cobalt transport system, permease K16785 - - 0.00000000000000000000000000000000000000000001742 171.0
DTH2_k127_6938507_21 NMD3 family K07562 - - 0.00000000000000000000000000000000000000000007188 173.0
DTH2_k127_6938507_22 DnaB-like helicase C terminal domain - - - 0.0000000000000000000005896 105.0
DTH2_k127_6938507_23 ECF-type riboflavin transporter, S component - - - 0.000000000000000000001968 101.0
DTH2_k127_6938507_24 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000002526 96.0
DTH2_k127_6938507_25 - - - - 0.000004022 58.0
DTH2_k127_6938507_26 Pfam:DUF1628 - - - 0.000005708 55.0
DTH2_k127_6938507_27 Carboxypeptidase regulatory-like domain - - - 0.00000589 59.0
DTH2_k127_6938507_28 Double zinc ribbon - - - 0.00001284 58.0
DTH2_k127_6938507_29 RDD family - - - 0.0002922 49.0
DTH2_k127_6938507_3 MCM OB domain K10726 - - 2.827e-215 690.0
DTH2_k127_6938507_30 zinc-ribbon domain - - - 0.0003048 51.0
DTH2_k127_6938507_4 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 520.0
DTH2_k127_6938507_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 501.0
DTH2_k127_6938507_6 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 377.0
DTH2_k127_6938507_7 Rad51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 336.0
DTH2_k127_6938507_8 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 324.0
DTH2_k127_6938507_9 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 302.0
DTH2_k127_6967335_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 3.037e-258 811.0
DTH2_k127_6967335_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.984e-199 644.0
DTH2_k127_6967335_10 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 353.0
DTH2_k127_6967335_11 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 348.0
DTH2_k127_6967335_12 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 328.0
DTH2_k127_6967335_13 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 321.0
DTH2_k127_6967335_14 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006743 289.0
DTH2_k127_6967335_15 Helix-turn-helix XRE-family like proteins K07731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008461 269.0
DTH2_k127_6967335_16 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008261 266.0
DTH2_k127_6967335_17 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
DTH2_k127_6967335_18 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002844 267.0
DTH2_k127_6967335_19 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002836 250.0
DTH2_k127_6967335_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 568.0
DTH2_k127_6967335_20 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000179 245.0
DTH2_k127_6967335_21 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000005736 236.0
DTH2_k127_6967335_22 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000001211 213.0
DTH2_k127_6967335_23 - - - - 0.0000000000000000000000000000000000000000000000000000001514 205.0
DTH2_k127_6967335_24 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000002432 192.0
DTH2_k127_6967335_25 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000003535 196.0
DTH2_k127_6967335_26 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000004147 201.0
DTH2_k127_6967335_27 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000593 173.0
DTH2_k127_6967335_28 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000003683 174.0
DTH2_k127_6967335_29 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000001425 169.0
DTH2_k127_6967335_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 565.0
DTH2_k127_6967335_30 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000003512 164.0
DTH2_k127_6967335_31 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000005402 166.0
DTH2_k127_6967335_32 Tubulin like - - - 0.000000000000000000000000000000000000007471 169.0
DTH2_k127_6967335_33 dTDP metabolic process K00943 - 2.7.4.9 0.0000000000000000000000000000000000001203 153.0
DTH2_k127_6967335_34 GHMP kinases N terminal domain K06982 - 2.7.1.169 0.0000000000000000000000000000000001111 144.0
DTH2_k127_6967335_35 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000001342 134.0
DTH2_k127_6967335_36 COG0328 Ribonuclease HI K03469 - 3.1.26.4 0.00000000000000000000000002036 113.0
DTH2_k127_6967335_37 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000623 107.0
DTH2_k127_6967335_38 - - - - 0.00000000000000000000136 107.0
DTH2_k127_6967335_39 metal ion binding - - - 0.0000000000000000000682 94.0
DTH2_k127_6967335_4 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 496.0
DTH2_k127_6967335_40 Lrp/AsnC ligand binding domain - - - 0.000000000000004717 78.0
DTH2_k127_6967335_41 Domain of unknown function (DUF4382) - - - 0.00000000008278 70.0
DTH2_k127_6967335_42 Belongs to the UPF0235 family K09131 - - 0.000000001675 63.0
DTH2_k127_6967335_43 protein conserved in archaea K09723 - - 0.00000003041 64.0
DTH2_k127_6967335_44 haloacid dehalogenase-like hydrolase K07025 - - 0.00000004046 63.0
DTH2_k127_6967335_45 - - - - 0.0000004912 59.0
DTH2_k127_6967335_46 KEOPS complex Cgi121-like subunit K09119 - - 0.0000133 54.0
DTH2_k127_6967335_5 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 503.0
DTH2_k127_6967335_6 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 486.0
DTH2_k127_6967335_7 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 441.0
DTH2_k127_6967335_8 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 437.0
DTH2_k127_6967335_9 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01620 - 2.3.1.29,2.3.1.47,4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 434.0
DTH2_k127_7074653_0 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 339.0
DTH2_k127_7074653_1 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000002336 199.0
DTH2_k127_7074653_2 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000001085 175.0
DTH2_k127_7074653_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000005903 158.0
DTH2_k127_7074653_4 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000007953 121.0
DTH2_k127_7122210_0 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 424.0
DTH2_k127_7122210_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 408.0
DTH2_k127_7122210_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 361.0
DTH2_k127_7122210_3 Iron dependent K03709 - - 0.000000000000000000000000000000000000000000003215 173.0
DTH2_k127_7122210_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000006114 130.0
DTH2_k127_7122210_5 Citrate transporter K14445 - - 0.0000000000000000000001256 99.0
DTH2_k127_7245108_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002451 223.0
DTH2_k127_7245108_1 PFAM UBA THIF-type NAD FAD binding protein - - - 0.000000000000000000000000000000000000000001536 166.0
DTH2_k127_7245108_2 Ubiquitin-conjugating enzyme E2, catalytic domain homologues K13960 GO:0000209,GO:0003674,GO:0003682,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006513,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0033554,GO:0034641,GO:0035519,GO:0036211,GO:0036297,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044314,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0051865,GO:0061630,GO:0061631,GO:0061650,GO:0061659,GO:0070013,GO:0070534,GO:0070647,GO:0070936,GO:0070979,GO:0071704,GO:0085020,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.2.23 0.0000000001508 68.0
DTH2_k127_7319776_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 349.0
DTH2_k127_7319776_1 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.000000000000000000000000000007953 123.0
DTH2_k127_7319776_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000003503 66.0
DTH2_k127_75382_0 Citrate transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
DTH2_k127_75382_1 Beta-lactamase enzyme family K07258,K17836 - 3.4.16.4,3.5.2.6 0.000000000000000004861 96.0
DTH2_k127_75382_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0002103 45.0
DTH2_k127_7627887_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 369.0
DTH2_k127_7627887_1 Major Facilitator Superfamily - - - 0.000000000138 69.0
DTH2_k127_7627887_2 Peptidase m28 - - - 0.00000005805 66.0
DTH2_k127_7629096_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.643e-305 957.0
DTH2_k127_7629096_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 396.0
DTH2_k127_7629096_10 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.00000000001134 72.0
DTH2_k127_7629096_2 TPR Domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000005099 229.0
DTH2_k127_7629096_3 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001189 171.0
DTH2_k127_7629096_4 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000003207 168.0
DTH2_k127_7629096_5 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000000008664 145.0
DTH2_k127_7629096_6 Response regulator receiver domain - - - 0.0000000000000000000000001166 113.0
DTH2_k127_7629096_7 DNA-binding transcription factor activity K18297 - - 0.0000000000000000000002152 107.0
DTH2_k127_7629096_8 Pfam:DUF552 K09152 - - 0.000000000001221 72.0
DTH2_k127_7629096_9 Pas domain - - - 0.000000000001901 76.0
DTH2_k127_7674651_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1062.0
DTH2_k127_7674651_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.598e-241 766.0
DTH2_k127_7674651_10 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 382.0
DTH2_k127_7674651_11 ABC transporter K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 376.0
DTH2_k127_7674651_12 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 366.0
DTH2_k127_7674651_13 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 363.0
DTH2_k127_7674651_14 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 360.0
DTH2_k127_7674651_15 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 328.0
DTH2_k127_7674651_16 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 296.0
DTH2_k127_7674651_17 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 297.0
DTH2_k127_7674651_18 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
DTH2_k127_7674651_19 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000008592 244.0
DTH2_k127_7674651_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 570.0
DTH2_k127_7674651_20 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001904 242.0
DTH2_k127_7674651_21 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
DTH2_k127_7674651_22 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000001862 239.0
DTH2_k127_7674651_23 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000258 228.0
DTH2_k127_7674651_24 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000005924 214.0
DTH2_k127_7674651_25 PFAM Major Facilitator Superfamily K19576 - - 0.0000000000000000000000000000000000000000000000000000000001314 218.0
DTH2_k127_7674651_26 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000002137 199.0
DTH2_k127_7674651_27 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000001593 198.0
DTH2_k127_7674651_28 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000002037 188.0
DTH2_k127_7674651_29 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000003181 192.0
DTH2_k127_7674651_3 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 526.0
DTH2_k127_7674651_30 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000000000000004177 198.0
DTH2_k127_7674651_31 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000187 192.0
DTH2_k127_7674651_32 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000499 172.0
DTH2_k127_7674651_33 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000001046 130.0
DTH2_k127_7674651_34 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000005663 123.0
DTH2_k127_7674651_35 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000006752 95.0
DTH2_k127_7674651_36 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000004711 94.0
DTH2_k127_7674651_37 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000001682 86.0
DTH2_k127_7674651_38 - - - - 0.000000000000001244 80.0
DTH2_k127_7674651_39 Helix-turn-helix domain - - - 0.000000000000009873 80.0
DTH2_k127_7674651_4 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 514.0
DTH2_k127_7674651_40 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000002974 80.0
DTH2_k127_7674651_41 transcriptional regulators - - - 0.00000000001986 69.0
DTH2_k127_7674651_42 - - - - 0.00000000004918 65.0
DTH2_k127_7674651_43 EamA-like transporter family - - - 0.0000002613 61.0
DTH2_k127_7674651_44 Protein of unknown function (DUF835) - - - 0.000001321 63.0
DTH2_k127_7674651_45 Lrp/AsnC ligand binding domain - - - 0.00003569 49.0
DTH2_k127_7674651_46 - - - - 0.0001175 47.0
DTH2_k127_7674651_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 518.0
DTH2_k127_7674651_6 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 491.0
DTH2_k127_7674651_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 463.0
DTH2_k127_7674651_8 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 421.0
DTH2_k127_7674651_9 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 385.0
DTH2_k127_7705533_0 CobW/HypB/UreG, nucleotide-binding domain - - - 7.024e-197 621.0
DTH2_k127_7705533_1 MGS-like domain K00602,K01492 - 2.1.2.2,2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 556.0
DTH2_k127_7705533_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000008724 136.0
DTH2_k127_7705533_11 PFAM Rieske 2Fe-2S domain K05710 - - 0.0000000000000000000000004179 108.0
DTH2_k127_7705533_12 - - - - 0.00000000000000000000002578 104.0
DTH2_k127_7705533_13 transcriptional regulators - - - 0.000000000000000007107 88.0
DTH2_k127_7705533_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000001833 76.0
DTH2_k127_7705533_15 nucleic-acid-binding protein containing a Zn-ribbon K00074,K07068 - 1.1.1.157 0.0000005871 56.0
DTH2_k127_7705533_16 Circadian clock protein KaiC - - - 0.00005115 53.0
DTH2_k127_7705533_2 aldo keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 489.0
DTH2_k127_7705533_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 397.0
DTH2_k127_7705533_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 246.0
DTH2_k127_7705533_5 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000007943 233.0
DTH2_k127_7705533_6 PFAM GvpD gas vesicle - - - 0.000000000000000000000000000000000000000000000000007707 199.0
DTH2_k127_7705533_7 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000006189 183.0
DTH2_k127_7705533_8 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000005418 169.0
DTH2_k127_7705533_9 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000004814 130.0
DTH2_k127_791403_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1021.0
DTH2_k127_791403_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.144e-226 729.0
DTH2_k127_791403_10 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003426 258.0
DTH2_k127_791403_11 LUD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001642 244.0
DTH2_k127_791403_12 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.000000000000000000000000000000000000000000000000000000002657 214.0
DTH2_k127_791403_13 Membrane - - - 0.00000000000000000000000000000000000000007175 160.0
DTH2_k127_791403_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000001694 145.0
DTH2_k127_791403_15 Universal stress protein family - - - 0.00000000000000000000000000000001309 133.0
DTH2_k127_791403_16 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000006009 140.0
DTH2_k127_791403_17 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000013 133.0
DTH2_k127_791403_18 Beta-lactamase enzyme family K01467,K17836 - 3.5.2.6 0.000000000000000000000000000000337 137.0
DTH2_k127_791403_19 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000004256 132.0
DTH2_k127_791403_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.017e-210 676.0
DTH2_k127_791403_20 Methyltransferase type 11 - - - 0.0000000000000000000000000001874 123.0
DTH2_k127_791403_21 Peptidase S8 K08651 - 3.4.21.66 0.000000000000000000000002141 121.0
DTH2_k127_791403_22 LUD domain K00782 - - 0.000000000000000000000004222 106.0
DTH2_k127_791403_23 - - - - 0.000000000000000000001014 100.0
DTH2_k127_791403_24 serine threonine protein kinase - - - 0.0000000000000000000533 99.0
DTH2_k127_791403_25 Pfam:DUF59 - - - 0.0000000000000000008653 89.0
DTH2_k127_791403_26 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000003056 86.0
DTH2_k127_791403_27 PAP2 superfamily - - - 0.00000000000000003633 92.0
DTH2_k127_791403_28 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03768 - 5.2.1.8 0.00000000002104 75.0
DTH2_k127_791403_29 cell adhesion involved in biofilm formation - - - 0.00000001307 69.0
DTH2_k127_791403_3 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 5.524e-195 623.0
DTH2_k127_791403_30 Molybdopterin converting factor, small subunit K03636 - - 0.0000076 51.0
DTH2_k127_791403_31 Nuclear matrix constituent protein 1-like - GO:0000229,GO:0000785,GO:0000789,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005652,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0005911,GO:0006996,GO:0006997,GO:0008150,GO:0009506,GO:0009987,GO:0012505,GO:0016043,GO:0030054,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032535,GO:0034399,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0055044,GO:0065007,GO:0065008,GO:0070013,GO:0071840,GO:0090066,GO:0097298 - 0.0004246 53.0
DTH2_k127_791403_4 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 547.0
DTH2_k127_791403_5 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 424.0
DTH2_k127_791403_6 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 356.0
DTH2_k127_791403_7 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 319.0
DTH2_k127_791403_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002725 285.0
DTH2_k127_791403_9 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003755 267.0
DTH2_k127_7987962_0 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000002367 148.0
DTH2_k127_7987962_1 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.00000000000000000000000000000001222 147.0
DTH2_k127_8039856_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 567.0
DTH2_k127_8039856_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 528.0
DTH2_k127_8039856_10 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000003472 181.0
DTH2_k127_8039856_11 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000006783 141.0
DTH2_k127_8039856_12 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000001793 116.0
DTH2_k127_8039856_13 ACT domain protein - - - 0.000000000000002609 80.0
DTH2_k127_8039856_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 514.0
DTH2_k127_8039856_3 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 413.0
DTH2_k127_8039856_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 390.0
DTH2_k127_8039856_5 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006588 277.0
DTH2_k127_8039856_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003215 264.0
DTH2_k127_8039856_7 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
DTH2_k127_8039856_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000005677 231.0
DTH2_k127_8039856_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000002318 181.0
DTH2_k127_8104008_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.007e-262 833.0
DTH2_k127_8104008_1 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 572.0
DTH2_k127_8104008_10 SMART ATPase, AAA type, core K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005073 268.0
DTH2_k127_8104008_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005955 254.0
DTH2_k127_8104008_12 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004265 247.0
DTH2_k127_8104008_13 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000001647 201.0
DTH2_k127_8104008_14 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000003368 203.0
DTH2_k127_8104008_15 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000003481 213.0
DTH2_k127_8104008_16 - - - - 0.00000000000000000000000000000000000000000000000002925 188.0
DTH2_k127_8104008_17 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000001031 181.0
DTH2_k127_8104008_18 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000001387 160.0
DTH2_k127_8104008_19 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000000000003175 144.0
DTH2_k127_8104008_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 560.0
DTH2_k127_8104008_20 - - - - 0.0000000000000000000000000000000002252 145.0
DTH2_k127_8104008_21 PFAM Peptidase - - - 0.0000000000000000000000000000001334 132.0
DTH2_k127_8104008_22 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000037 130.0
DTH2_k127_8104008_23 cheY-homologous receiver domain - - - 0.00000000000000000000004406 111.0
DTH2_k127_8104008_24 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000001225 94.0
DTH2_k127_8104008_25 Tetratricopeptide repeat - - - 0.000000000000000009591 98.0
DTH2_k127_8104008_26 - - - - 0.000000000000001464 85.0
DTH2_k127_8104008_27 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000168 85.0
DTH2_k127_8104008_28 RNA secondary structure unwinding K03724 - - 0.00000003925 67.0
DTH2_k127_8104008_29 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000003662 64.0
DTH2_k127_8104008_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 550.0
DTH2_k127_8104008_30 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000002022 59.0
DTH2_k127_8104008_31 DNA replication initiation - - - 0.00002003 53.0
DTH2_k127_8104008_32 Domain of unknown function (DUF749) - - - 0.00003865 49.0
DTH2_k127_8104008_33 V4R K07013 - - 0.0002068 53.0
DTH2_k127_8104008_34 Acetyltransferase (GNAT) domain - - - 0.0003277 52.0
DTH2_k127_8104008_4 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 533.0
DTH2_k127_8104008_5 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 480.0
DTH2_k127_8104008_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 372.0
DTH2_k127_8104008_7 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 358.0
DTH2_k127_8104008_8 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 304.0
DTH2_k127_8104008_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 293.0
DTH2_k127_8129164_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.808e-243 764.0
DTH2_k127_8129164_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 2.972e-228 732.0
DTH2_k127_8129164_10 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006254 262.0
DTH2_k127_8129164_11 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001444 264.0
DTH2_k127_8129164_12 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000001207 250.0
DTH2_k127_8129164_13 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000007608 223.0
DTH2_k127_8129164_14 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000007395 199.0
DTH2_k127_8129164_15 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000471 192.0
DTH2_k127_8129164_16 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000001198 185.0
DTH2_k127_8129164_17 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000001926 181.0
DTH2_k127_8129164_18 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000001027 182.0
DTH2_k127_8129164_19 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000001006 167.0
DTH2_k127_8129164_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 525.0
DTH2_k127_8129164_20 AAA domain - - - 0.0000000000000000000000000000000000000000001229 165.0
DTH2_k127_8129164_21 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000000000000005476 178.0
DTH2_k127_8129164_22 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000001159 153.0
DTH2_k127_8129164_23 DsrE/DsrF-like family K07235 - - 0.000000000000000000000000000000001374 132.0
DTH2_k127_8129164_24 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000001216 124.0
DTH2_k127_8129164_25 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000001505 113.0
DTH2_k127_8129164_26 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000002022 112.0
DTH2_k127_8129164_27 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000001889 112.0
DTH2_k127_8129164_28 Response regulator receiver domain - - - 0.000000000000000000008451 100.0
DTH2_k127_8129164_29 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000002966 94.0
DTH2_k127_8129164_3 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 430.0
DTH2_k127_8129164_30 transferase activity, transferring glycosyl groups - - - 0.0000000000000000001222 102.0
DTH2_k127_8129164_31 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000229 105.0
DTH2_k127_8129164_32 ABC-2 family transporter protein K01992 - - 0.00000000000000002736 94.0
DTH2_k127_8129164_33 4Fe-4S dicluster domain - - - 0.0000000000000001247 83.0
DTH2_k127_8129164_34 protein involved in the oxidation of intracellular sulfur K07236 - - 0.0000000000000002096 83.0
DTH2_k127_8129164_35 Glucose / Sorbosone dehydrogenase - - - 0.000000001412 73.0
DTH2_k127_8129164_36 Roadblock/LC7 domain K07131 - - 0.000000001453 63.0
DTH2_k127_8129164_37 Transcription factor TFIID (or TATA-binding protein, TBP) - - - 0.000000049 60.0
DTH2_k127_8129164_38 sulfur relay protein TusB DsrH K07237 - - 0.00002197 50.0
DTH2_k127_8129164_39 OmpA family K02557,K03286 - - 0.0001105 57.0
DTH2_k127_8129164_4 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 396.0
DTH2_k127_8129164_40 Domain of unknown function (DUF2383) K03594 - 1.16.3.1 0.0001343 50.0
DTH2_k127_8129164_41 PFAM Bacterial membrane flanked domain - - - 0.0001857 51.0
DTH2_k127_8129164_42 domain protein - - - 0.0008591 54.0
DTH2_k127_8129164_5 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
DTH2_k127_8129164_6 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 312.0
DTH2_k127_8129164_7 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 314.0
DTH2_k127_8129164_8 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 296.0
DTH2_k127_8129164_9 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003602 277.0
DTH2_k127_8136819_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1167.0
DTH2_k127_8136819_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.786e-251 786.0
DTH2_k127_8136819_10 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002013 207.0
DTH2_k127_8136819_11 - - - - 0.000000000000000000000000000000000000000000000000000155 190.0
DTH2_k127_8136819_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000002596 176.0
DTH2_k127_8136819_13 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000008835 178.0
DTH2_k127_8136819_14 - - - - 0.0000000000000000000000000000000000000000002471 166.0
DTH2_k127_8136819_15 VIT family - - - 0.00000000000000000000000000000000000524 144.0
DTH2_k127_8136819_16 Transcriptional regulator K07722 - - 0.00000000000000000000000000311 118.0
DTH2_k127_8136819_17 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters K02008 - - 0.000000000001901 76.0
DTH2_k127_8136819_18 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000351 51.0
DTH2_k127_8136819_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.739e-247 792.0
DTH2_k127_8136819_3 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 302.0
DTH2_k127_8136819_4 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 298.0
DTH2_k127_8136819_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 295.0
DTH2_k127_8136819_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001772 273.0
DTH2_k127_8136819_7 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004738 248.0
DTH2_k127_8136819_8 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000844 233.0
DTH2_k127_8136819_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000007799 223.0
DTH2_k127_81659_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 322.0
DTH2_k127_81659_1 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001842 272.0
DTH2_k127_81659_2 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004485 264.0
DTH2_k127_81659_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000124 263.0
DTH2_k127_81659_4 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000995 224.0
DTH2_k127_81659_5 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity) K04484 - - 0.0000000000000000000000000000000000000000000000005131 181.0
DTH2_k127_81659_6 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000001879 123.0
DTH2_k127_81659_7 domain, Protein - - - 0.0001202 53.0
DTH2_k127_8184345_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 463.0
DTH2_k127_8184345_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 437.0
DTH2_k127_8184345_2 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 397.0
DTH2_k127_8184345_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 377.0
DTH2_k127_8184345_4 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000001349 211.0
DTH2_k127_8184345_5 - - - - 0.00000000000000001895 88.0
DTH2_k127_8184345_6 Sugar (and other) transporter - - - 0.0000001315 56.0
DTH2_k127_8246615_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 461.0
DTH2_k127_8246615_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 449.0
DTH2_k127_8246615_2 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000000003635 210.0
DTH2_k127_8878508_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 376.0
DTH2_k127_8878508_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 318.0
DTH2_k127_8878508_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 306.0
DTH2_k127_8878508_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001453 262.0
DTH2_k127_8878508_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002936 258.0
DTH2_k127_8878508_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005669 261.0
DTH2_k127_8881101_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1445.0
DTH2_k127_8881101_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.153e-229 733.0
DTH2_k127_8881101_10 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 409.0
DTH2_k127_8881101_11 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 400.0
DTH2_k127_8881101_12 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 400.0
DTH2_k127_8881101_13 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 389.0
DTH2_k127_8881101_14 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 375.0
DTH2_k127_8881101_15 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 332.0
DTH2_k127_8881101_16 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 329.0
DTH2_k127_8881101_17 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 311.0
DTH2_k127_8881101_18 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 309.0
DTH2_k127_8881101_19 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003612 254.0
DTH2_k127_8881101_2 AAA domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 613.0
DTH2_k127_8881101_20 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000000003753 261.0
DTH2_k127_8881101_21 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001134 245.0
DTH2_k127_8881101_22 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001403 240.0
DTH2_k127_8881101_23 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003522 238.0
DTH2_k127_8881101_24 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000816 220.0
DTH2_k127_8881101_25 - - - - 0.000000000000000000000000000000000000000000000000000000004276 209.0
DTH2_k127_8881101_26 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000002288 207.0
DTH2_k127_8881101_27 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000001267 188.0
DTH2_k127_8881101_28 Archaeal holliday junction resolvase (hjc) - - - 0.0000000000000000000000000000000000000000000000001872 181.0
DTH2_k127_8881101_29 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000000000000000000000002914 199.0
DTH2_k127_8881101_3 PUA domain containing protein K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 578.0
DTH2_k127_8881101_30 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000000001606 174.0
DTH2_k127_8881101_31 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000002013 174.0
DTH2_k127_8881101_32 PFAM Pyruvate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000002866 171.0
DTH2_k127_8881101_33 LysE type translocator - - - 0.0000000000000000000000000000000000000000009715 164.0
DTH2_k127_8881101_34 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000000001201 151.0
DTH2_k127_8881101_35 - - - - 0.000000000000000000000000000000000009976 147.0
DTH2_k127_8881101_36 Phosphatidylserine decarboxylase K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000002216 142.0
DTH2_k127_8881101_37 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000009359 110.0
DTH2_k127_8881101_38 EamA-like transporter family - - - 0.00000000000000000005388 101.0
DTH2_k127_8881101_39 EamA-like transporter family - - - 0.000000000000000001844 88.0
DTH2_k127_8881101_4 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 512.0
DTH2_k127_8881101_40 YHS domain - - - 0.000000000000000006624 85.0
DTH2_k127_8881101_41 COG1522 Transcriptional regulators - - - 0.00000000000000001536 91.0
DTH2_k127_8881101_42 CDP-alcohol phosphatidyltransferase K17103 GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.8 0.00000000000000005348 91.0
DTH2_k127_8881101_43 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000001889 81.0
DTH2_k127_8881101_44 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000002142 79.0
DTH2_k127_8881101_45 - - - - 0.000000002219 68.0
DTH2_k127_8881101_46 Ribbon-helix-helix protein, copG family K07722 - - 0.000003514 54.0
DTH2_k127_8881101_47 Sulfur transfer protein involved in thiamine biosynthesis K03154,K21947 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.8.1.15 0.00003588 48.0
DTH2_k127_8881101_48 Zinc finger domain - - - 0.00008039 50.0
DTH2_k127_8881101_49 GDP-mannose mannosyl hydrolase activity - - - 0.0009113 50.0
DTH2_k127_8881101_5 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 479.0
DTH2_k127_8881101_6 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 474.0
DTH2_k127_8881101_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 466.0
DTH2_k127_8881101_8 Toprim domain K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 444.0
DTH2_k127_8881101_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 446.0
DTH2_k127_8965249_0 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000004872 183.0
DTH2_k127_8965249_1 ABC-type antimicrobial peptide transport system, permease component - - - 0.0000000000000000000000005024 122.0
DTH2_k127_8965249_2 ABC transporter (Permease) K02004 - - 0.00008091 54.0
DTH2_k127_9049378_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 595.0
DTH2_k127_9049378_1 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 559.0
DTH2_k127_9049378_10 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002092 289.0
DTH2_k127_9049378_11 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 260.0
DTH2_k127_9049378_12 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008269 251.0
DTH2_k127_9049378_13 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000002918 200.0
DTH2_k127_9049378_14 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000002783 180.0
DTH2_k127_9049378_15 chemotaxis protein K03406 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000008704 181.0
DTH2_k127_9049378_16 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000008069 147.0
DTH2_k127_9049378_17 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000022 147.0
DTH2_k127_9049378_18 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000505 134.0
DTH2_k127_9049378_19 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000008135 139.0
DTH2_k127_9049378_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 431.0
DTH2_k127_9049378_20 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000001434 129.0
DTH2_k127_9049378_21 PFAM CBS domain containing protein - - - 0.0000000000000000000000000001141 121.0
DTH2_k127_9049378_22 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000001255 112.0
DTH2_k127_9049378_23 CheC-like family K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.0000000000000000000001239 105.0
DTH2_k127_9049378_24 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0003851 45.0
DTH2_k127_9049378_25 - - - - 0.0004308 46.0
DTH2_k127_9049378_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 439.0
DTH2_k127_9049378_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 392.0
DTH2_k127_9049378_5 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 357.0
DTH2_k127_9049378_6 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 333.0
DTH2_k127_9049378_7 PFAM isocitrate isopropylmalate dehydrogenase K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 302.0
DTH2_k127_9049378_8 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 301.0
DTH2_k127_9049378_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 297.0
DTH2_k127_9052765_0 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 404.0
DTH2_k127_9052765_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 391.0
DTH2_k127_9052765_10 Saccharopine dehydrogenase K00290,K19064 - 1.4.1.18,1.5.1.7 0.0000000000000000000000000000000000005213 154.0
DTH2_k127_9052765_11 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000009934 124.0
DTH2_k127_9052765_12 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000003255 125.0
DTH2_k127_9052765_13 SMART Excinuclease ABC C subunit domain protein - - - 0.0000000000000000000000000647 119.0
DTH2_k127_9052765_14 Protein of unknown function (DUF1614) - - - 0.00000000000000009162 92.0
DTH2_k127_9052765_15 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000004303 81.0
DTH2_k127_9052765_16 Methyl-viologen-reducing hydrogenase, delta subunit K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000742 72.0
DTH2_k127_9052765_17 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000005573 78.0
DTH2_k127_9052765_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 370.0
DTH2_k127_9052765_3 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 351.0
DTH2_k127_9052765_4 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000135 276.0
DTH2_k127_9052765_5 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006734 250.0
DTH2_k127_9052765_6 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000001308 213.0
DTH2_k127_9052765_7 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000003521 208.0
DTH2_k127_9052765_8 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.0000000000000000000000000000000000000001951 159.0
DTH2_k127_9052765_9 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000001441 166.0
DTH2_k127_9090261_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 501.0
DTH2_k127_9090261_1 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007478 275.0
DTH2_k127_9090261_2 Lamin Tail Domain - - - 0.0000000000000000000000000000000000000000000000000000008841 222.0
DTH2_k127_9090261_3 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000001861 196.0
DTH2_k127_9090261_4 Putative diphthamide synthesis protein K07561 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016765,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0048037,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.5.1.108 0.00000000000000000000000187 108.0
DTH2_k127_9090261_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000008313 82.0
DTH2_k127_9090261_6 CRS1_YhbY K07574 - - 0.0000000001202 65.0
DTH2_k127_9104548_0 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000000000000000000000000000000000000001138 216.0
DTH2_k127_9104548_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000448 195.0
DTH2_k127_9104548_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000005494 133.0
DTH2_k127_9104548_3 - - - - 0.000008642 57.0
DTH2_k127_9104548_4 Belongs to the ompA family K20276 - - 0.0001016 55.0
DTH2_k127_9131808_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 450.0
DTH2_k127_9131808_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 453.0
DTH2_k127_9131808_10 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000001431 123.0
DTH2_k127_9131808_11 - - - - 0.0000000000000000000000007918 104.0
DTH2_k127_9131808_12 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000001424 107.0
DTH2_k127_9131808_13 - - - - 0.00000000000000000009619 95.0
DTH2_k127_9131808_14 Histidine kinase-like ATPases - - - 0.00000000000001023 88.0
DTH2_k127_9131808_15 - - - - 0.0000000000001759 73.0
DTH2_k127_9131808_16 Right handed beta helix region - - - 0.000000000166 71.0
DTH2_k127_9131808_17 Transcription factor zinc-finger - - - 0.0000002301 61.0
DTH2_k127_9131808_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 430.0
DTH2_k127_9131808_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 339.0
DTH2_k127_9131808_4 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 304.0
DTH2_k127_9131808_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
DTH2_k127_9131808_6 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000241 203.0
DTH2_k127_9131808_7 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001536 174.0
DTH2_k127_9131808_8 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000001896 159.0
DTH2_k127_9131808_9 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000000000000006665 143.0
DTH2_k127_9389807_0 Aminopeptidase Iap family-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004511 269.0
DTH2_k127_9389807_1 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007049 262.0
DTH2_k127_9389807_2 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
DTH2_k127_9389807_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000001297 186.0
DTH2_k127_9389807_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000009583 96.0
DTH2_k127_9404337_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 434.0
DTH2_k127_9404337_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 280.0
DTH2_k127_9404337_2 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000001018 252.0
DTH2_k127_9404337_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000001993 220.0
DTH2_k127_9404337_4 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000004417 169.0
DTH2_k127_9404337_5 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000001192 95.0
DTH2_k127_9404337_6 translation initiation factor activity K03680 - - 0.00000000000000001898 93.0
DTH2_k127_9851202_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 2.097e-228 757.0
DTH2_k127_9851202_1 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 616.0
DTH2_k127_9851202_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000001741 233.0
DTH2_k127_9851202_3 Methyltransferase type 12 - - - 0.000000000000000000000004048 111.0
DTH2_k127_9851202_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000001612 86.0
DTH2_k127_9851202_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0003157 46.0
DTH2_k127_9851202_6 ACT domain protein - - - 0.0004528 48.0
DTH2_k127_9851202_7 Predicted RNA-binding protein - - - 0.0005303 44.0
DTH2_k127_9898427_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 587.0
DTH2_k127_9898427_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 560.0
DTH2_k127_9898427_10 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000009727 93.0
DTH2_k127_9898427_11 binds to the 23S rRNA K02922 - - 0.0000000000000000007781 86.0
DTH2_k127_9898427_12 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000123 87.0
DTH2_k127_9898427_2 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 380.0
DTH2_k127_9898427_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 342.0
DTH2_k127_9898427_4 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000001966 237.0
DTH2_k127_9898427_5 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000001508 198.0
DTH2_k127_9898427_6 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000001252 138.0
DTH2_k127_9898427_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000007182 128.0
DTH2_k127_9898427_8 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000003506 101.0
DTH2_k127_9898427_9 Roadblock LC7 family protein K07131 - - 0.000000000000000000004211 96.0