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Overview

ID MAG00765
Name DTH2_bin.22
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Rhodocyclaceae
Genus Sulfuritalea
Species
Assembly information
Completeness (%) 95.36
Contamination (%) 1.69
GC content (%) 64.0
N50 (bp) 13,607
Genome size (bp) 3,157,731

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3137

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_102377_0 DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 482.0
DTH2_k127_102377_1 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 470.0
DTH2_k127_102377_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 467.0
DTH2_k127_102377_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 372.0
DTH2_k127_102377_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002027 270.0
DTH2_k127_102377_5 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000009771 253.0
DTH2_k127_102377_6 Sulfurtransferase TusA K04085 - - 0.000000000000000000000000000000038 129.0
DTH2_k127_102377_7 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000005702 117.0
DTH2_k127_102553_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1116.0
DTH2_k127_102553_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1074.0
DTH2_k127_102553_10 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 550.0
DTH2_k127_102553_11 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 467.0
DTH2_k127_102553_12 signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 447.0
DTH2_k127_102553_13 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 428.0
DTH2_k127_102553_14 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 389.0
DTH2_k127_102553_15 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 321.0
DTH2_k127_102553_16 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 314.0
DTH2_k127_102553_17 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 256.0
DTH2_k127_102553_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003818 244.0
DTH2_k127_102553_19 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000005687 238.0
DTH2_k127_102553_2 Phosphate acyltransferases - - - 9.44e-322 1011.0
DTH2_k127_102553_20 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000707 244.0
DTH2_k127_102553_21 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
DTH2_k127_102553_22 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000000000225 213.0
DTH2_k127_102553_23 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000001764 210.0
DTH2_k127_102553_24 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000009854 167.0
DTH2_k127_102553_25 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000004412 116.0
DTH2_k127_102553_26 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000000002622 102.0
DTH2_k127_102553_27 Disulfide bond formation protein DsbB K03611 - - 0.0000000000000000000004853 102.0
DTH2_k127_102553_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 8.504e-318 988.0
DTH2_k127_102553_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.512e-296 915.0
DTH2_k127_102553_5 Belongs to the aldehyde dehydrogenase family K00135 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114 1.2.1.16,1.2.1.20,1.2.1.79 1.522e-226 709.0
DTH2_k127_102553_6 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.844e-224 698.0
DTH2_k127_102553_7 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 4.598e-213 671.0
DTH2_k127_102553_8 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 586.0
DTH2_k127_102553_9 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 557.0
DTH2_k127_1081755_0 oxidoreductase activity - - - 0.0 1067.0
DTH2_k127_1081755_1 Surface antigen K07001 - - 2.179e-260 826.0
DTH2_k127_1081755_10 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 316.0
DTH2_k127_1081755_11 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001518 275.0
DTH2_k127_1081755_12 - - - - 0.00000000000000000000000000000000000000000000000000000000006458 213.0
DTH2_k127_1081755_13 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000001057 189.0
DTH2_k127_1081755_14 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000000000000000002989 187.0
DTH2_k127_1081755_15 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000006447 171.0
DTH2_k127_1081755_16 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000000000000000006542 156.0
DTH2_k127_1081755_17 - - - - 0.000000000000000000000000000000000000006652 153.0
DTH2_k127_1081755_18 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000000000000106 152.0
DTH2_k127_1081755_19 - - - - 0.00000000000000000000000000000003097 131.0
DTH2_k127_1081755_2 GMC oxidoreductase - - - 4.503e-235 737.0
DTH2_k127_1081755_20 acyl-coA-binding protein - - - 0.0000000000000000000000000000000367 127.0
DTH2_k127_1081755_3 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 606.0
DTH2_k127_1081755_4 Aldehyde dehydrogenase family K00154 - 1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 550.0
DTH2_k127_1081755_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 495.0
DTH2_k127_1081755_6 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 476.0
DTH2_k127_1081755_7 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 446.0
DTH2_k127_1081755_8 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 422.0
DTH2_k127_1081755_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 329.0
DTH2_k127_1242999_0 - - - - 0.0000000000000000000000000000000000000003764 150.0
DTH2_k127_1242999_1 Transcriptional regulator - - - 0.00000000000000000000000000000005088 128.0
DTH2_k127_1242999_2 Type II transport protein GspH K08084 - - 0.000000000000000008826 91.0
DTH2_k127_1242999_3 Type IV Pilus-assembly protein W K02672 - - 0.00000000000001293 84.0
DTH2_k127_1242999_4 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000000001497 79.0
DTH2_k127_1242999_5 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000002602 65.0
DTH2_k127_1242999_6 Domain of unknown function (DUF4143) - - - 0.0009593 44.0
DTH2_k127_1275628_0 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 599.0
DTH2_k127_1275628_1 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001757 220.0
DTH2_k127_1275628_2 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000003552 222.0
DTH2_k127_1275628_3 - - - - 0.00000000000000000000000000000000006864 144.0
DTH2_k127_1275628_4 lipoprotein - - - 0.00000000000000000000000000005071 118.0
DTH2_k127_1275628_5 - - - - 0.00000000000000000000000001929 119.0
DTH2_k127_1275628_6 Sulfotransferase family - - - 0.00000000000000000000000003263 122.0
DTH2_k127_1275628_7 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000002266 81.0
DTH2_k127_128998_0 Site-specific recombinase - - - 1.303e-223 713.0
DTH2_k127_128998_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 428.0
DTH2_k127_128998_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 351.0
DTH2_k127_128998_3 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001462 264.0
DTH2_k127_128998_4 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 266.0
DTH2_k127_128998_5 - - - - 0.000000000000000000000000000000000000000000000239 179.0
DTH2_k127_128998_6 Periplasmic Protein - - - 0.00000000000000214 82.0
DTH2_k127_128998_7 Protein of unknown function (DUF2917) - - - 0.0000004963 58.0
DTH2_k127_1299424_0 Sulfate transporter antisigma-factor antagonist STAS - - - 2.749e-273 852.0
DTH2_k127_1299424_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 534.0
DTH2_k127_1299424_2 lipid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 480.0
DTH2_k127_1299424_3 Sulfate permease and related transporters (MFS superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002824 275.0
DTH2_k127_1299424_4 - - - - 0.0000000000000000000461 94.0
DTH2_k127_1307094_0 cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000003546 189.0
DTH2_k127_1307094_1 - - - - 0.000000000000000000000000000000000000000000000009209 179.0
DTH2_k127_1307094_2 Cytochrome c - - - 0.000000000000000000000000004757 126.0
DTH2_k127_1307094_3 - - - - 0.000000000000000002193 97.0
DTH2_k127_1307094_4 PFAM cytochrome c, class I K08738 - - 0.000000000003932 70.0
DTH2_k127_1307094_5 cytochrome - - - 0.0004306 53.0
DTH2_k127_1346044_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 466.0
DTH2_k127_1346044_1 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 358.0
DTH2_k127_1346044_2 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 310.0
DTH2_k127_1346044_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001111 273.0
DTH2_k127_1346044_4 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000005609 218.0
DTH2_k127_1359503_0 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 1.068e-198 622.0
DTH2_k127_1359503_1 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 351.0
DTH2_k127_1359503_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 362.0
DTH2_k127_1359503_3 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000000000251 186.0
DTH2_k127_1359503_4 - - - - 0.00000000000000000000000000000000000000001158 160.0
DTH2_k127_1359503_5 DsrC like protein K11179 - - 0.000000000000000000000000000000000001147 142.0
DTH2_k127_1359503_6 Cas6 Crispr - - - 0.0000000000000000000000000000000009557 143.0
DTH2_k127_1359503_7 - - - - 0.0000000000000000005242 89.0
DTH2_k127_1359503_8 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.000000000000000006835 83.0
DTH2_k127_1367449_0 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 6.09e-221 689.0
DTH2_k127_1367449_1 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 360.0
DTH2_k127_1367449_2 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 331.0
DTH2_k127_1367449_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 287.0
DTH2_k127_1367449_4 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000000000000000008875 215.0
DTH2_k127_1367449_5 DsrE/DsrF-like family K07236 - - 0.000000000000000000000000000000000000000000000000000000000001686 210.0
DTH2_k127_1367449_6 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000009644 202.0
DTH2_k127_1367449_7 DsrH like protein K07237 - - 0.00000000000000000000000000000000000001493 146.0
DTH2_k127_1368591_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1010.0
DTH2_k127_1368591_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 8.864e-226 705.0
DTH2_k127_1368591_10 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 360.0
DTH2_k127_1368591_11 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 316.0
DTH2_k127_1368591_12 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000001904 243.0
DTH2_k127_1368591_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000373 239.0
DTH2_k127_1368591_14 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000017 172.0
DTH2_k127_1368591_15 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000006289 143.0
DTH2_k127_1368591_16 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000000845 106.0
DTH2_k127_1368591_17 protein conserved in bacteria K09937 - - 0.00000000000000000003223 91.0
DTH2_k127_1368591_2 Malate synthase K01638 - 2.3.3.9 1.735e-212 661.0
DTH2_k127_1368591_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 584.0
DTH2_k127_1368591_4 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 551.0
DTH2_k127_1368591_5 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 543.0
DTH2_k127_1368591_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 543.0
DTH2_k127_1368591_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 495.0
DTH2_k127_1368591_8 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 473.0
DTH2_k127_1368591_9 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 428.0
DTH2_k127_1368675_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 511.0
DTH2_k127_1368675_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 477.0
DTH2_k127_1368675_2 ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 455.0
DTH2_k127_1368675_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 298.0
DTH2_k127_1368675_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 254.0
DTH2_k127_1368675_5 FKBP-type peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000002059 189.0
DTH2_k127_1368675_6 - - - - 0.000000000000000000000000000000000000309 143.0
DTH2_k127_1373212_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.081e-315 980.0
DTH2_k127_1373212_1 aminopeptidase N K01256 - 3.4.11.2 5.922e-296 934.0
DTH2_k127_1373212_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 513.0
DTH2_k127_1373212_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 464.0
DTH2_k127_1373212_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 353.0
DTH2_k127_1373212_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000003044 231.0
DTH2_k127_1374460_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2346.0
DTH2_k127_1374460_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 529.0
DTH2_k127_1384778_0 von Willebrand factor type A domain - - - 1.63e-237 780.0
DTH2_k127_1384778_1 COG1538 Outer membrane protein K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 595.0
DTH2_k127_1384778_2 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000971 270.0
DTH2_k127_1384778_3 - - - - 0.000000000000000000000000002029 120.0
DTH2_k127_1384778_4 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.00000499 57.0
DTH2_k127_1386356_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.548e-234 739.0
DTH2_k127_1386356_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.341e-222 694.0
DTH2_k127_1386356_2 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 522.0
DTH2_k127_1386356_3 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 412.0
DTH2_k127_1386356_4 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 392.0
DTH2_k127_1386356_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 266.0
DTH2_k127_1386356_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000001843 227.0
DTH2_k127_1386356_7 Iron-sulfur cluster assembly transcription factor K13643 - - 0.00000000000000000000000000000000000000000000000000000000000001082 220.0
DTH2_k127_1386356_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000004866 77.0
DTH2_k127_1433094_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.722e-219 686.0
DTH2_k127_1433094_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 373.0
DTH2_k127_1433094_2 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002573 279.0
DTH2_k127_1433094_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000007492 207.0
DTH2_k127_1433094_4 - - - - 0.000000000000000000000000000007997 121.0
DTH2_k127_1433094_5 spectrin binding - - - 0.00000000000000004325 89.0
DTH2_k127_1459068_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704 4.1.3.1 1.536e-266 824.0
DTH2_k127_1459068_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 508.0
DTH2_k127_1459068_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 430.0
DTH2_k127_1459068_3 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 319.0
DTH2_k127_1459068_4 Belongs to the ClpA ClpB family K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001279 247.0
DTH2_k127_1459068_5 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003945 247.0
DTH2_k127_1461312_0 Belongs to the peptidase S16 family - - - 0.0 1213.0
DTH2_k127_1461312_1 Heat shock 70 kDa protein K04043 - - 0.0 1028.0
DTH2_k127_1461312_2 DNA polymerase X family K02347 - - 1.632e-276 859.0
DTH2_k127_1461312_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 2.275e-235 758.0
DTH2_k127_1461312_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 549.0
DTH2_k127_1461312_5 Homospermidine synthase K00808 - 2.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 420.0
DTH2_k127_1461312_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004443 285.0
DTH2_k127_1461312_7 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002133 281.0
DTH2_k127_1461312_8 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000000000001725 204.0
DTH2_k127_1461312_9 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000000000001725 181.0
DTH2_k127_146665_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 3.92e-248 776.0
DTH2_k127_146665_1 Belongs to the thiolase family - - - 4.829e-214 674.0
DTH2_k127_146665_2 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 524.0
DTH2_k127_146665_3 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000259 228.0
DTH2_k127_146665_4 FCD - - - 0.0000000000000000000000000000000000000000000000002553 185.0
DTH2_k127_146665_5 PEP-CTERM motif - - - 0.00000000168 59.0
DTH2_k127_146665_7 - - - - 0.0001163 51.0
DTH2_k127_1469923_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 1.09e-313 982.0
DTH2_k127_1469923_1 Putative modulator of DNA gyrase K03568 - - 1.653e-229 721.0
DTH2_k127_1469923_2 Carbon-nitrogen hydrolase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 385.0
DTH2_k127_1469923_3 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 286.0
DTH2_k127_1469923_4 Molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002509 291.0
DTH2_k127_1469923_5 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000001008 213.0
DTH2_k127_1469923_6 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000002751 164.0
DTH2_k127_1506462_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 514.0
DTH2_k127_1506462_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 455.0
DTH2_k127_1506462_2 Belongs to the GST superfamily K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 391.0
DTH2_k127_1506462_3 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 371.0
DTH2_k127_1506462_4 COG0845 Membrane-fusion protein K16300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 256.0
DTH2_k127_1506462_5 ABC transporter transmembrane region K06148,K12536 - - 0.0000000000000000000000000000000000000000000000000000001064 204.0
DTH2_k127_1506462_6 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000004859 161.0
DTH2_k127_1514100_0 of ABC transporters with duplicated ATPase - - - 1.597e-291 901.0
DTH2_k127_1514100_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 498.0
DTH2_k127_1514100_2 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 443.0
DTH2_k127_1514100_3 PFAM binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 254.0
DTH2_k127_1514100_4 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007882 245.0
DTH2_k127_1514100_5 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000001759 197.0
DTH2_k127_1514100_6 Type II restriction enzyme, methylase subunits - - - 0.00000000000000000000000000000000000000004639 154.0
DTH2_k127_1514100_7 - - - - 0.000000000000000000000000000000001134 135.0
DTH2_k127_1514100_8 PIN domain K07065 - - 0.0000000000000000000000000001091 126.0
DTH2_k127_1514100_9 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0006339 46.0
DTH2_k127_1544901_0 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 2.02e-222 696.0
DTH2_k127_1544901_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 601.0
DTH2_k127_1544901_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000005165 74.0
DTH2_k127_1544901_11 - - - - 0.0000001844 63.0
DTH2_k127_1544901_2 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 576.0
DTH2_k127_1544901_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 489.0
DTH2_k127_1544901_4 phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 480.0
DTH2_k127_1544901_5 Mg2 and Co2 transporter CorC K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 413.0
DTH2_k127_1544901_6 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 396.0
DTH2_k127_1544901_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 350.0
DTH2_k127_1544901_8 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001334 293.0
DTH2_k127_1544901_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000007281 186.0
DTH2_k127_1550072_0 Belongs to the peptidase S16 family - - - 9.182e-289 908.0
DTH2_k127_1550072_1 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 565.0
DTH2_k127_1550072_2 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 500.0
DTH2_k127_1550072_3 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 505.0
DTH2_k127_1550072_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 288.0
DTH2_k127_1550072_5 Hsp90 protein K04079 - - 0.0000000000000000000000000000000000000000000009851 167.0
DTH2_k127_1550072_6 DsrC like protein - - - 0.00000000000000000000000000000000000002063 146.0
DTH2_k127_1550072_7 - - - - 0.00000001974 58.0
DTH2_k127_1596084_0 Protein of unknown function - - - 2.293e-255 838.0
DTH2_k127_1596084_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006516 278.0
DTH2_k127_16039_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 423.0
DTH2_k127_16039_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 391.0
DTH2_k127_16039_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000003341 128.0
DTH2_k127_1616553_0 Aldehyde dehydrogenase family K00141 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 514.0
DTH2_k127_1616553_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 445.0
DTH2_k127_1616553_2 Transcriptional regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 305.0
DTH2_k127_1616553_3 Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
DTH2_k127_1616553_4 - - - - 0.00000000000000000000000000005547 123.0
DTH2_k127_1616553_5 RNA-binding K14761 - - 0.0000000000000007214 83.0
DTH2_k127_1624351_0 Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 K07006,K22343,K22444 - 1.14.13.238,1.14.13.239 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 530.0
DTH2_k127_1624351_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 378.0
DTH2_k127_1624351_2 lytic transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 323.0
DTH2_k127_1624351_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 289.0
DTH2_k127_1624351_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 290.0
DTH2_k127_1624351_5 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000007013 249.0
DTH2_k127_1624351_6 ABC transporter K01990,K21397 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000001237 69.0
DTH2_k127_1649320_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08356 - 1.20.2.1,1.20.9.1 1.044e-252 809.0
DTH2_k127_1649320_1 Alpha-methylacyl-CoA racemase K01796 - 5.1.99.4 4.026e-199 625.0
DTH2_k127_1649320_10 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000000000000001244 177.0
DTH2_k127_1649320_11 arsenite oxidase, small subunit K08355 - 1.20.2.1,1.20.9.1 0.0000000000000000000000000000000000000001309 155.0
DTH2_k127_1649320_12 Cytochrome c - - - 0.00000000000000000000000000000000000006599 146.0
DTH2_k127_1649320_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000006443 103.0
DTH2_k127_1649320_14 Type III restriction - - - 0.00000000000000009465 81.0
DTH2_k127_1649320_15 Cytochrome c - - - 0.00002871 54.0
DTH2_k127_1649320_2 Protein of unknown function (DUF1329) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 541.0
DTH2_k127_1649320_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 371.0
DTH2_k127_1649320_4 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 358.0
DTH2_k127_1649320_5 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004203 270.0
DTH2_k127_1649320_6 Protein of unknown function (DUF1302) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000636 274.0
DTH2_k127_1649320_7 Methylamine dehydrogenase accessory protein MauD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003457 270.0
DTH2_k127_1649320_8 helix_turn_helix, arabinose operon control protein K04033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002616 261.0
DTH2_k127_1649320_9 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009289 245.0
DTH2_k127_1659737_0 Protein of unknown function (DUF4080) - - - 2.101e-222 702.0
DTH2_k127_1659737_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003527 282.0
DTH2_k127_1659737_10 PFAM Integrase core domain - - - 0.00001275 47.0
DTH2_k127_1659737_2 restriction endonuclease K07454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 264.0
DTH2_k127_1659737_3 Scavenger mRNA decapping enzyme C-term binding - - - 0.0000000000000000000000000000000000000000000000000000000009703 204.0
DTH2_k127_1659737_4 nucleic acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000000000001927 148.0
DTH2_k127_1659737_5 cytochrome c5 - - - 0.00000000000000000000000000000000000312 142.0
DTH2_k127_1659737_6 Putative quorum-sensing-regulated virulence factor K09954 - - 0.000000000000000000000000000000000009481 137.0
DTH2_k127_1659737_7 Ribbon-helix-helix domain - - - 0.00000000000000000000000006052 109.0
DTH2_k127_1659737_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000409 108.0
DTH2_k127_1659737_9 - - - - 0.000000002387 62.0
DTH2_k127_1661393_0 twitching motility protein K02670 - - 1.613e-203 637.0
DTH2_k127_1661393_1 twitching motility protein K02669 - - 6.792e-199 623.0
DTH2_k127_1661393_10 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000003186 119.0
DTH2_k127_1661393_11 - - - - 0.0000000000006978 73.0
DTH2_k127_1661393_2 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 577.0
DTH2_k127_1661393_3 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 479.0
DTH2_k127_1661393_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 469.0
DTH2_k127_1661393_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 350.0
DTH2_k127_1661393_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 319.0
DTH2_k127_1661393_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
DTH2_k127_1661393_8 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000006899 192.0
DTH2_k127_1661393_9 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000003985 153.0
DTH2_k127_1667582_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.4e-322 996.0
DTH2_k127_1667582_1 Cytochrome c bacterial - - - 6.003e-246 769.0
DTH2_k127_1667582_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 415.0
DTH2_k127_1667582_3 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 336.0
DTH2_k127_1667582_4 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000134 252.0
DTH2_k127_1667582_5 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000005411 182.0
DTH2_k127_1667582_6 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000006744 181.0
DTH2_k127_1668660_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 611.0
DTH2_k127_1668660_1 COG1450 Type II secretory pathway, component PulD K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 587.0
DTH2_k127_1668660_11 General secretion pathway protein H K02457 - - 0.00001161 55.0
DTH2_k127_1668660_2 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 337.0
DTH2_k127_1668660_3 general secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000001474 246.0
DTH2_k127_1668660_4 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000006908 227.0
DTH2_k127_1668660_5 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000000004747 128.0
DTH2_k127_1668660_6 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000219 98.0
DTH2_k127_1668660_7 sugar transferase K03606 - - 0.00000000001794 66.0
DTH2_k127_1668660_8 Type II secretion system (T2SS), protein L K02461 - - 0.00000000008269 74.0
DTH2_k127_1668660_9 Type II secretion system protein C K02452 - - 0.0000000002628 67.0
DTH2_k127_1767272_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 6.317e-201 634.0
DTH2_k127_1767272_1 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 608.0
DTH2_k127_1767272_10 Protein of unknown function (DUF3299) K09950 - - 0.0000000000000000000000000000000000000000000000000004126 202.0
DTH2_k127_1767272_11 Protein of unknown function (DUF2796) - - - 0.00000000000000000000000000000000000000000009054 177.0
DTH2_k127_1767272_12 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000003624 135.0
DTH2_k127_1767272_13 peptidase S16 K07157 - - 0.0000000000000000000000219 102.0
DTH2_k127_1767272_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 579.0
DTH2_k127_1767272_3 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 570.0
DTH2_k127_1767272_4 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 492.0
DTH2_k127_1767272_5 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 438.0
DTH2_k127_1767272_6 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 427.0
DTH2_k127_1767272_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 409.0
DTH2_k127_1767272_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 325.0
DTH2_k127_1767272_9 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000000008375 201.0
DTH2_k127_1782570_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.824e-230 720.0
DTH2_k127_1782570_1 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 603.0
DTH2_k127_1782570_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000001241 220.0
DTH2_k127_1782570_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000006569 186.0
DTH2_k127_1782570_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000006997 136.0
DTH2_k127_1782570_5 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000005695 140.0
DTH2_k127_1782641_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1088.0
DTH2_k127_1782641_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1069.0
DTH2_k127_1782641_10 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.000000000000000000000000006772 109.0
DTH2_k127_1782641_11 - - - - 0.000000000002877 68.0
DTH2_k127_1782641_2 homoserine dehydrogenase K00003 - 1.1.1.3 3.737e-230 717.0
DTH2_k127_1782641_3 Threonine synthase K01733 - 4.2.3.1 5.839e-230 719.0
DTH2_k127_1782641_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 528.0
DTH2_k127_1782641_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 461.0
DTH2_k127_1782641_6 NADH flavin K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 351.0
DTH2_k127_1782641_7 RmlD substrate binding domain K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 319.0
DTH2_k127_1782641_8 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000005376 276.0
DTH2_k127_1782641_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000002297 188.0
DTH2_k127_1782827_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 541.0
DTH2_k127_1782827_1 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 481.0
DTH2_k127_1782827_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 294.0
DTH2_k127_1782827_3 - - - - 0.000000000000000000000000000001122 125.0
DTH2_k127_1782827_4 - - - - 0.0000000000000307 76.0
DTH2_k127_1806011_0 Signal transduction histidine kinase K11711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 606.0
DTH2_k127_1806011_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 545.0
DTH2_k127_1806011_2 response regulator K11712 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
DTH2_k127_1806011_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000365 240.0
DTH2_k127_1806011_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.0000000000002277 73.0
DTH2_k127_1810425_0 FAD linked oxidase - - - 0.0 1654.0
DTH2_k127_1810425_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 333.0
DTH2_k127_1810425_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000017 286.0
DTH2_k127_1810425_3 TPM domain - - - 0.000000000000000000000000000000000000000007061 159.0
DTH2_k127_1810425_4 cell filamentation protein Fic K04095 - - 0.0000000000000000000000000000005848 133.0
DTH2_k127_183599_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 6.335e-200 630.0
DTH2_k127_183599_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 562.0
DTH2_k127_183599_10 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000001628 213.0
DTH2_k127_183599_11 Gram-negative porin K03285 - - 0.000000000000000000000000000000000000000000000000000000006507 214.0
DTH2_k127_183599_12 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000001191 177.0
DTH2_k127_183599_13 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000004557 152.0
DTH2_k127_183599_14 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000005144 152.0
DTH2_k127_183599_15 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000306 153.0
DTH2_k127_183599_16 - - - - 0.000000000000000000000000000000006204 147.0
DTH2_k127_183599_17 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000007703 111.0
DTH2_k127_183599_19 Protein of unknown function DUF86 - - - 0.00000000000000000000001466 109.0
DTH2_k127_183599_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 546.0
DTH2_k127_183599_21 Nucleotidyltransferase domain K07075 - - 0.0001254 46.0
DTH2_k127_183599_22 Protein of unknown function DUF86 - - - 0.0008371 48.0
DTH2_k127_183599_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 539.0
DTH2_k127_183599_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 471.0
DTH2_k127_183599_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 434.0
DTH2_k127_183599_6 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 428.0
DTH2_k127_183599_7 Long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 409.0
DTH2_k127_183599_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000023 271.0
DTH2_k127_183599_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000009116 227.0
DTH2_k127_1842739_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1054.0
DTH2_k127_1842739_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 4.856e-196 622.0
DTH2_k127_1842739_10 Ribonuclease III family K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000464 269.0
DTH2_k127_1842739_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001066 244.0
DTH2_k127_1842739_12 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004466 236.0
DTH2_k127_1842739_13 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000005523 190.0
DTH2_k127_1842739_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000116 170.0
DTH2_k127_1842739_15 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000002641 168.0
DTH2_k127_1842739_16 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000007855 161.0
DTH2_k127_1842739_17 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000002615 161.0
DTH2_k127_1842739_18 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000007945 155.0
DTH2_k127_1842739_19 Protein-S-isoprenylcysteine methyltransferase - - - 0.000000000000000000000000000000000000003166 153.0
DTH2_k127_1842739_2 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 464.0
DTH2_k127_1842739_21 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000004142 139.0
DTH2_k127_1842739_22 sequence-specific DNA binding - - - 0.000000000000000000000000001151 115.0
DTH2_k127_1842739_23 Domain of unknown function (DUF4845) - - - 0.0000000000000000000002663 101.0
DTH2_k127_1842739_24 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.0000000000000000000007736 98.0
DTH2_k127_1842739_25 Positive regulator of sigma(E), RseC/MucC - - - 0.0000000000001046 78.0
DTH2_k127_1842739_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 428.0
DTH2_k127_1842739_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 418.0
DTH2_k127_1842739_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 407.0
DTH2_k127_1842739_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 407.0
DTH2_k127_1842739_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
DTH2_k127_1842739_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001565 287.0
DTH2_k127_1842739_9 Sigma E regulatory protein, MucB RseB K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004371 274.0
DTH2_k127_1856172_0 glutamine synthetase K01915 - 6.3.1.2 2.153e-288 888.0
DTH2_k127_1856172_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 5.716e-237 740.0
DTH2_k127_1856172_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 598.0
DTH2_k127_1856172_3 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 483.0
DTH2_k127_1856172_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 406.0
DTH2_k127_1856172_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000005478 226.0
DTH2_k127_1856172_6 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000004915 115.0
DTH2_k127_1856172_7 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000008619 110.0
DTH2_k127_1872073_0 integrase family - - - 9.904e-216 687.0
DTH2_k127_1872073_1 Domain of unknown function (DUF4113) K03502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 576.0
DTH2_k127_1872073_10 PFAM UMUC domain protein DNA-repair protein K03502 - - 0.00000000006106 71.0
DTH2_k127_1872073_2 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 529.0
DTH2_k127_1872073_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 531.0
DTH2_k127_1872073_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
DTH2_k127_1872073_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 389.0
DTH2_k127_1872073_6 Belongs to the peptidase S24 family K03503 - - 0.0000000000000000000000000000000000000000000000000002234 189.0
DTH2_k127_1872073_7 - - - - 0.000000000000000000000000000004675 124.0
DTH2_k127_1872073_8 helix_turn_helix, arabinose operon control protein K04033 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009438,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019172,GO:0019243,GO:0019249,GO:0019438,GO:0019752,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042180,GO:0042182,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0046483,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000000000001301 113.0
DTH2_k127_1872073_9 - - - - 0.0000000000000000000001058 102.0
DTH2_k127_189314_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 3.464e-217 681.0
DTH2_k127_189314_1 DEAD-like helicases superfamily K04066 - - 2.741e-211 677.0
DTH2_k127_189314_10 - - - - 0.00000000000000000007148 96.0
DTH2_k127_189314_11 Fe-S protein K06938 - - 0.00002405 54.0
DTH2_k127_189314_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 593.0
DTH2_k127_189314_3 AsmA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 528.0
DTH2_k127_189314_4 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 457.0
DTH2_k127_189314_5 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 399.0
DTH2_k127_189314_6 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 387.0
DTH2_k127_189314_7 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
DTH2_k127_189314_8 3-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000476 231.0
DTH2_k127_189314_9 MerR HTH family regulatory protein K18997 - - 0.000000000000000000000000000001222 125.0
DTH2_k127_1968541_0 Spermine/spermidine synthase domain K00797 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.5.1.16 6.331e-214 676.0
DTH2_k127_1968541_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 605.0
DTH2_k127_1968541_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000002123 86.0
DTH2_k127_1968541_11 PFAM Sporulation domain protein - - - 0.000000000000008802 83.0
DTH2_k127_1968541_12 Pfam:DUF1049 - - - 0.000000001372 65.0
DTH2_k127_1968541_2 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 524.0
DTH2_k127_1968541_3 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 381.0
DTH2_k127_1968541_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 347.0
DTH2_k127_1968541_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000003366 256.0
DTH2_k127_1968541_6 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000266 197.0
DTH2_k127_1968541_7 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797 - 2.5.1.16 0.00000000000000000000000000000000008337 148.0
DTH2_k127_1968541_8 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000001463 128.0
DTH2_k127_1968541_9 Protein conserved in bacteria - - - 0.000000000000000000002087 97.0
DTH2_k127_1986339_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 2.697e-214 671.0
DTH2_k127_1986339_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.833e-206 666.0
DTH2_k127_1986339_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.481e-197 617.0
DTH2_k127_1986339_3 TIGRFAM fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 592.0
DTH2_k127_1986339_4 Oligopeptidase K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 486.0
DTH2_k127_1986339_5 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 439.0
DTH2_k127_1986339_6 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000201 212.0
DTH2_k127_1986339_7 Phosphate-starvation-inducible E K13256 - - 0.00000000000000000000000000000000000000000004763 165.0
DTH2_k127_1986339_8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000846 68.0
DTH2_k127_1991446_0 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 577.0
DTH2_k127_1991446_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 497.0
DTH2_k127_1991446_2 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 456.0
DTH2_k127_1991446_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 458.0
DTH2_k127_1991446_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 398.0
DTH2_k127_1991446_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 340.0
DTH2_k127_1991446_6 Nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000000000000000000000001698 179.0
DTH2_k127_1991446_7 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.000000000002021 73.0
DTH2_k127_1991446_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0001018 47.0
DTH2_k127_2005347_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.626e-220 696.0
DTH2_k127_2005347_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 387.0
DTH2_k127_2005347_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000004718 149.0
DTH2_k127_204021_0 FAD linked oxidases, C-terminal domain K05797 - 1.17.99.1 1.872e-310 954.0
DTH2_k127_2099037_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
DTH2_k127_2099037_1 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 358.0
DTH2_k127_2099037_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000001669 122.0
DTH2_k127_2107958_0 Histidine kinase - - - 3.793e-241 771.0
DTH2_k127_2107958_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 462.0
DTH2_k127_2107958_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 333.0
DTH2_k127_2107958_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006383 254.0
DTH2_k127_2107958_4 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000003115 207.0
DTH2_k127_2107958_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000004256 78.0
DTH2_k127_2181196_0 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 421.0
DTH2_k127_2181196_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 319.0
DTH2_k127_2181196_2 SMART adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 329.0
DTH2_k127_2181196_3 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000004334 223.0
DTH2_k127_2181196_4 tellurite resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000012 213.0
DTH2_k127_2181196_5 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.0000000000000000000000000000000000000000000001859 174.0
DTH2_k127_2217370_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1270.0
DTH2_k127_2217370_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 6.285e-206 656.0
DTH2_k127_2217370_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 375.0
DTH2_k127_2221391_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 1.914e-247 773.0
DTH2_k127_2221391_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 9.268e-211 676.0
DTH2_k127_2221391_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 320.0
DTH2_k127_2221391_11 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 305.0
DTH2_k127_2221391_12 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001109 265.0
DTH2_k127_2221391_13 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004401 252.0
DTH2_k127_2221391_14 Periplasmic protein thiol disulfide oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003078 250.0
DTH2_k127_2221391_15 PFAM Glutathione S-transferase, N-terminal K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000385 254.0
DTH2_k127_2221391_16 - - - - 0.0000000000000000000001455 104.0
DTH2_k127_2221391_17 - - - - 0.0000000000000000003423 92.0
DTH2_k127_2221391_18 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000004404 90.0
DTH2_k127_2221391_19 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.0000000000001731 74.0
DTH2_k127_2221391_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 559.0
DTH2_k127_2221391_3 (Lipo)protein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 512.0
DTH2_k127_2221391_4 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 502.0
DTH2_k127_2221391_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 447.0
DTH2_k127_2221391_6 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 400.0
DTH2_k127_2221391_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 385.0
DTH2_k127_2221391_8 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 342.0
DTH2_k127_2221391_9 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 334.0
DTH2_k127_2229185_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1141.0
DTH2_k127_2229185_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.506e-230 721.0
DTH2_k127_2229185_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000006971 233.0
DTH2_k127_2229185_11 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000003622 192.0
DTH2_k127_2229185_12 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000002787 166.0
DTH2_k127_2229185_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 6.462e-221 691.0
DTH2_k127_2229185_3 phenylacetic acid degradation protein paaN - - - 9.584e-209 664.0
DTH2_k127_2229185_4 Belongs to the thiolase family K00632 - 2.3.1.16 1.009e-207 659.0
DTH2_k127_2229185_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 559.0
DTH2_k127_2229185_6 enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
DTH2_k127_2229185_7 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 374.0
DTH2_k127_2229185_8 Phenylacetic acid degradation protein PaaY K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009128 293.0
DTH2_k127_2229185_9 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002719 258.0
DTH2_k127_256248_0 Fumarate reductase flavoprotein C-term - - - 3.726e-249 782.0
DTH2_k127_256248_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.546e-210 660.0
DTH2_k127_256248_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 334.0
DTH2_k127_256248_11 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000002519 226.0
DTH2_k127_256248_12 Fumarate reductase subunit C - - - 0.00000000000000000000000001182 122.0
DTH2_k127_256248_14 Fumarate reductase subunit D - - - 0.0000000000000142 82.0
DTH2_k127_256248_15 preprotein translocase K03075 - - 0.00000002159 55.0
DTH2_k127_256248_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 522.0
DTH2_k127_256248_3 phosphate transport system K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 494.0
DTH2_k127_256248_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 482.0
DTH2_k127_256248_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 452.0
DTH2_k127_256248_6 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 412.0
DTH2_k127_256248_7 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 365.0
DTH2_k127_256248_8 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 345.0
DTH2_k127_256248_9 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 342.0
DTH2_k127_2565367_0 FAD binding domain K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 515.0
DTH2_k127_2565367_1 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 411.0
DTH2_k127_2565367_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
DTH2_k127_2565367_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 349.0
DTH2_k127_2593098_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.142e-214 671.0
DTH2_k127_2593098_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 8.77e-206 653.0
DTH2_k127_2593098_10 - - - - 0.0000228 50.0
DTH2_k127_2593098_11 LTXXQ motif family protein - - - 0.00003896 54.0
DTH2_k127_2593098_2 CoA-transferase family III K07749 - 2.8.3.16 1.504e-201 643.0
DTH2_k127_2593098_3 FAD-dependent pyridine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 506.0
DTH2_k127_2593098_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 334.0
DTH2_k127_2593098_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 319.0
DTH2_k127_2593098_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 307.0
DTH2_k127_2593098_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000003812 175.0
DTH2_k127_2593098_8 Mut7-C ubiquitin - - - 0.0000000000000000000000008447 106.0
DTH2_k127_2658863_0 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.851e-260 808.0
DTH2_k127_2658863_1 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 587.0
DTH2_k127_2658863_2 C4-dicarboxylate transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 535.0
DTH2_k127_2658863_3 enoyl-CoA hydratase K15513 - 4.1.2.44 0.00000000000000000000000000000000000000002403 152.0
DTH2_k127_2665187_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 9.956e-218 687.0
DTH2_k127_2665187_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 407.0
DTH2_k127_2665187_2 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 378.0
DTH2_k127_2665187_3 Glycine-zipper domain - - - 0.000000000000000000000009703 103.0
DTH2_k127_2667357_0 Sulfate transporter antisigma-factor antagonist STAS - - - 5.037e-299 933.0
DTH2_k127_2667357_1 Sulfate transporter antisigma-factor antagonist STAS - - - 2.553e-285 892.0
DTH2_k127_2667357_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 463.0
DTH2_k127_2667357_11 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 450.0
DTH2_k127_2667357_12 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005746 284.0
DTH2_k127_2667357_13 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003513 249.0
DTH2_k127_2667357_15 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07686 - - 0.00000000000000000000000000000005825 128.0
DTH2_k127_2667357_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000005132 82.0
DTH2_k127_2667357_2 Proton-conducting membrane transporter - - - 1.161e-280 876.0
DTH2_k127_2667357_3 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.023e-244 783.0
DTH2_k127_2667357_4 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 6.328e-238 742.0
DTH2_k127_2667357_5 Sigma-54 interaction domain - - - 2.008e-228 724.0
DTH2_k127_2667357_6 metal ion transport K14445 - - 2.216e-210 668.0
DTH2_k127_2667357_7 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 550.0
DTH2_k127_2667357_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 524.0
DTH2_k127_2667357_9 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101,K15054 - 1.1.2.3,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 490.0
DTH2_k127_269029_0 Belongs to the glutamate synthase family - - - 3.112e-244 765.0
DTH2_k127_269029_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.149e-214 670.0
DTH2_k127_269029_10 - - - - 0.0000000000000001001 83.0
DTH2_k127_269029_11 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000548 85.0
DTH2_k127_269029_12 - - - - 0.000000005184 63.0
DTH2_k127_269029_13 - - - - 0.0000001206 56.0
DTH2_k127_269029_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 6.77e-207 650.0
DTH2_k127_269029_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 449.0
DTH2_k127_269029_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 381.0
DTH2_k127_269029_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
DTH2_k127_269029_6 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005086 247.0
DTH2_k127_269029_7 phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000004976 240.0
DTH2_k127_269029_8 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000004743 189.0
DTH2_k127_269029_9 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000003173 162.0
DTH2_k127_2696613_0 nitrous oxide reductase K00376 - 1.7.2.4 0.0 1395.0
DTH2_k127_2696613_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 532.0
DTH2_k127_2696613_10 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000073 136.0
DTH2_k127_2696613_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 381.0
DTH2_k127_2696613_3 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 370.0
DTH2_k127_2696613_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 298.0
DTH2_k127_2696613_5 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001339 244.0
DTH2_k127_2696613_6 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000004039 227.0
DTH2_k127_2696613_7 COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.000000000000000000000000000000000000000000000000000000001563 205.0
DTH2_k127_2696613_8 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000001946 189.0
DTH2_k127_2696613_9 - - - - 0.0000000000000000000000000000000000000000006324 162.0
DTH2_k127_2705288_0 cytochrome - - - 2.288e-239 750.0
DTH2_k127_2705288_1 Cytochrome C and Quinol oxidase polypeptide I - - - 1.145e-215 681.0
DTH2_k127_2705288_10 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000001222 216.0
DTH2_k127_2705288_11 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000000000000001321 160.0
DTH2_k127_2705288_12 Protein of unknown function (DUF1318) K09978 - - 0.000000000000000000000000000000000000007205 154.0
DTH2_k127_2705288_13 - - - - 0.000000000000000000002305 103.0
DTH2_k127_2705288_14 - - - - 0.000000000000000002259 86.0
DTH2_k127_2705288_15 threonine efflux protein - - - 0.0000005163 55.0
DTH2_k127_2705288_2 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 591.0
DTH2_k127_2705288_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 439.0
DTH2_k127_2705288_4 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 337.0
DTH2_k127_2705288_5 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 352.0
DTH2_k127_2705288_6 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 302.0
DTH2_k127_2705288_7 NosL - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 297.0
DTH2_k127_2705288_8 SCO1/SenC K07152 GO:0000041,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016020,GO:0016043,GO:0016209,GO:0016491,GO:0016684,GO:0019866,GO:0022607,GO:0030001,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034622,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0051775,GO:0051920,GO:0055114,GO:0065003,GO:0070887,GO:0071840,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 299.0
DTH2_k127_2705288_9 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000008509 237.0
DTH2_k127_2719608_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 496.0
DTH2_k127_2719608_1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 468.0
DTH2_k127_2719608_2 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 372.0
DTH2_k127_2719608_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 362.0
DTH2_k127_2719608_4 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 323.0
DTH2_k127_2719608_5 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 307.0
DTH2_k127_2719608_6 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000001234 210.0
DTH2_k127_2731914_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1539.0
DTH2_k127_2731914_1 MMPL family K07003 - - 1.248e-305 955.0
DTH2_k127_2731914_10 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004506 276.0
DTH2_k127_2731914_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000002728 264.0
DTH2_k127_2731914_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003363 251.0
DTH2_k127_2731914_13 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000007688 226.0
DTH2_k127_2731914_14 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000008284 183.0
DTH2_k127_2731914_15 ankyrin repeat K06867 - - 0.00000000000000000000000000000000000003529 151.0
DTH2_k127_2731914_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 4.111e-305 941.0
DTH2_k127_2731914_3 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 4.556e-274 849.0
DTH2_k127_2731914_4 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 584.0
DTH2_k127_2731914_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 402.0
DTH2_k127_2731914_6 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 347.0
DTH2_k127_2731914_7 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 329.0
DTH2_k127_2731914_8 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 305.0
DTH2_k127_2731914_9 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005184 282.0
DTH2_k127_2733541_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1336.0
DTH2_k127_2733541_1 extracellular solute-binding protein - - - 4.793e-236 741.0
DTH2_k127_2733541_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.999e-225 702.0
DTH2_k127_2733541_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 595.0
DTH2_k127_2733541_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 452.0
DTH2_k127_2733541_5 extracellular solute-binding protein - - - 0.00000000000000000000007715 102.0
DTH2_k127_2733541_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000575 90.0
DTH2_k127_2733541_7 - - - - 0.00000002137 56.0
DTH2_k127_2744558_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1457.0
DTH2_k127_2744558_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 536.0
DTH2_k127_2744558_10 Phasin protein - - - 0.00000000000000000000000000000000002846 140.0
DTH2_k127_2744558_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000000003558 116.0
DTH2_k127_2744558_12 PFAM SpoVT AbrB domain protein - - - 0.00000000000000000000000001486 114.0
DTH2_k127_2744558_13 PIN domain - - - 0.000000000000000000000001117 108.0
DTH2_k127_2744558_14 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000001221 63.0
DTH2_k127_2744558_2 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 508.0
DTH2_k127_2744558_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 488.0
DTH2_k127_2744558_4 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 345.0
DTH2_k127_2744558_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000001266 230.0
DTH2_k127_2744558_6 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000004408 222.0
DTH2_k127_2744558_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000003337 202.0
DTH2_k127_2744558_8 TIGRFAM death-on-curing family protein K07341 - - 0.000000000000000000000000000000000000000000000000004192 184.0
DTH2_k127_2744558_9 Protein of unknown function (DUF1304) K08987 - - 0.000000000000000000000000000000000000000002075 158.0
DTH2_k127_2760551_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 466.0
DTH2_k127_2760551_1 ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 398.0
DTH2_k127_2760551_10 - - - - 0.00000000000000000000000000000000000000001851 172.0
DTH2_k127_2760551_11 membrane - - - 0.00000000000000000000000000000002457 129.0
DTH2_k127_2760551_12 - - - - 0.0000000000000000000000000000001091 127.0
DTH2_k127_2760551_13 VanZ like family - - - 0.000000000000000000000000000004446 122.0
DTH2_k127_2760551_14 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000008293 123.0
DTH2_k127_2760551_15 - - - - 0.0000000000000000003308 96.0
DTH2_k127_2760551_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 366.0
DTH2_k127_2760551_3 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 325.0
DTH2_k127_2760551_4 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004174 278.0
DTH2_k127_2760551_5 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001314 259.0
DTH2_k127_2760551_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000001016 235.0
DTH2_k127_2760551_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000002381 223.0
DTH2_k127_2760551_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000002459 185.0
DTH2_k127_2760551_9 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000005779 158.0
DTH2_k127_2781025_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1174.0
DTH2_k127_2781025_1 carboxylase K01965 - 6.4.1.3 0.0 1014.0
DTH2_k127_2781025_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 3.951e-303 933.0
DTH2_k127_2781025_3 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 448.0
DTH2_k127_2781025_4 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007569 267.0
DTH2_k127_2781025_5 - - - - 0.0000000001332 65.0
DTH2_k127_2781025_6 thiosulfate sulfurtransferase activity - - - 0.00000003873 55.0
DTH2_k127_2814193_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 5.85e-263 821.0
DTH2_k127_2814193_1 Diguanylate cyclase - - - 3.845e-218 722.0
DTH2_k127_2814193_10 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 361.0
DTH2_k127_2814193_11 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 307.0
DTH2_k127_2814193_12 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000156 280.0
DTH2_k127_2814193_13 synthesis repressor, PhaR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 266.0
DTH2_k127_2814193_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003295 261.0
DTH2_k127_2814193_15 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000348 241.0
DTH2_k127_2814193_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004103 233.0
DTH2_k127_2814193_17 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000000000000000000000000002329 191.0
DTH2_k127_2814193_18 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000002181 160.0
DTH2_k127_2814193_19 - - - - 0.000000000000000002196 86.0
DTH2_k127_2814193_2 Pfam Transposase - - - 2.917e-198 623.0
DTH2_k127_2814193_20 histone H2A K63-linked ubiquitination - - - 0.00000000001849 72.0
DTH2_k127_2814193_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 5.869e-195 621.0
DTH2_k127_2814193_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 479.0
DTH2_k127_2814193_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 457.0
DTH2_k127_2814193_6 mechanosensitive K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 432.0
DTH2_k127_2814193_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 420.0
DTH2_k127_2814193_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 383.0
DTH2_k127_2814193_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
DTH2_k127_2887120_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1106.0
DTH2_k127_2887120_1 Amp-dependent synthetase and ligase K08295 - 6.2.1.32 1.309e-255 800.0
DTH2_k127_2887120_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 322.0
DTH2_k127_2887120_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
DTH2_k127_2887120_12 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002591 222.0
DTH2_k127_2887120_13 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000002411 187.0
DTH2_k127_2887120_14 - - - - 0.0000000000000000000000000000000000000000006552 166.0
DTH2_k127_2887120_15 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000000000001985 126.0
DTH2_k127_2887120_16 Thioesterase superfamily K01075 - 3.1.2.23 0.000000000000000000000000000007618 122.0
DTH2_k127_2887120_17 - - - - 0.000000000000001806 85.0
DTH2_k127_2887120_2 AMP-binding enzyme C-terminal domain - - - 1.22e-233 734.0
DTH2_k127_2887120_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 587.0
DTH2_k127_2887120_4 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 561.0
DTH2_k127_2887120_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 402.0
DTH2_k127_2887120_6 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 370.0
DTH2_k127_2887120_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 369.0
DTH2_k127_2887120_8 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 357.0
DTH2_k127_2887120_9 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 335.0
DTH2_k127_2946418_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 533.0
DTH2_k127_2946418_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 466.0
DTH2_k127_2946418_2 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 336.0
DTH2_k127_2946418_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 277.0
DTH2_k127_2946418_4 Allophanate hydrolase subunit 2 K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000001488 271.0
DTH2_k127_2946418_5 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000001069 231.0
DTH2_k127_2949111_0 - - - - 0.0 1553.0
DTH2_k127_2949111_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1550.0
DTH2_k127_2949111_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 323.0
DTH2_k127_2949111_11 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 310.0
DTH2_k127_2949111_12 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001594 281.0
DTH2_k127_2949111_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003289 259.0
DTH2_k127_2949111_14 Transcriptional regulator crp fnr family K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006496 253.0
DTH2_k127_2949111_15 Cytidylyltransferase-like K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000004846 257.0
DTH2_k127_2949111_16 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001796 248.0
DTH2_k127_2949111_17 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000000000002303 211.0
DTH2_k127_2949111_18 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000000000000001168 200.0
DTH2_k127_2949111_19 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000009066 186.0
DTH2_k127_2949111_2 transporter K03319 - - 2.93e-285 881.0
DTH2_k127_2949111_20 HIRAN - - - 0.000000000000000000000000000000000000006765 150.0
DTH2_k127_2949111_21 nucleic acid phosphodiester bond hydrolysis K07460 - - 0.00000000000000000000000000000000000002711 148.0
DTH2_k127_2949111_22 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.000000000000000000000000000000002688 129.0
DTH2_k127_2949111_23 PIN domain - - - 0.00000000000000000000000000000001849 132.0
DTH2_k127_2949111_24 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000005035 130.0
DTH2_k127_2949111_25 - - - - 0.0000000000000000000000006092 115.0
DTH2_k127_2949111_28 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00004623 51.0
DTH2_k127_2949111_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 9.782e-260 807.0
DTH2_k127_2949111_4 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 586.0
DTH2_k127_2949111_5 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 530.0
DTH2_k127_2949111_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 519.0
DTH2_k127_2949111_7 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 476.0
DTH2_k127_2949111_8 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 436.0
DTH2_k127_2949111_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 347.0
DTH2_k127_295186_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1702.0
DTH2_k127_295186_1 HsdM N-terminal domain K03427 - 2.1.1.72 0.0 1274.0
DTH2_k127_295186_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - - 2.568e-204 640.0
DTH2_k127_295186_3 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 369.0
DTH2_k127_295186_4 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 362.0
DTH2_k127_295186_5 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 313.0
DTH2_k127_295186_6 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004178 273.0
DTH2_k127_295186_7 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.00000000000000000000000000000000000000000000002498 174.0
DTH2_k127_295186_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000008898 110.0
DTH2_k127_2968135_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1083.0
DTH2_k127_2968135_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.21e-239 747.0
DTH2_k127_2968135_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.116e-231 721.0
DTH2_k127_2968135_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 565.0
DTH2_k127_2968135_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 544.0
DTH2_k127_2969748_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 577.0
DTH2_k127_2969748_1 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 502.0
DTH2_k127_2969748_2 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 364.0
DTH2_k127_2969748_3 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 339.0
DTH2_k127_2969748_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 304.0
DTH2_k127_2969748_5 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000006156 264.0
DTH2_k127_2969748_6 PFAM Glycoside hydrolase 15-related - - - 0.0000000000001888 69.0
DTH2_k127_2979348_0 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 458.0
DTH2_k127_2979348_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 432.0
DTH2_k127_2979348_2 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 353.0
DTH2_k127_2979348_3 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002472 274.0
DTH2_k127_2979348_4 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000000003698 216.0
DTH2_k127_2979348_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000001576 184.0
DTH2_k127_2979348_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000113 169.0
DTH2_k127_2979348_7 sulfuric ester hydrolase activity - - - 0.0000000001916 72.0
DTH2_k127_303644_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 1.457e-215 680.0
DTH2_k127_303644_1 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 391.0
DTH2_k127_303644_2 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000003749 202.0
DTH2_k127_303644_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000007198 146.0
DTH2_k127_303644_4 - - - - 0.0000000000000000003761 100.0
DTH2_k127_303644_5 heptosyltransferase II K02843 - - 0.00000000005041 63.0
DTH2_k127_3158005_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.255e-233 733.0
DTH2_k127_3158005_1 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 453.0
DTH2_k127_3158005_2 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 404.0
DTH2_k127_3158005_3 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002736 284.0
DTH2_k127_3158005_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001415 232.0
DTH2_k127_3158005_5 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000004492 138.0
DTH2_k127_3158005_6 EamA-like transporter family - - - 0.0000000000000000000000009512 111.0
DTH2_k127_3158005_7 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.000000000000008361 74.0
DTH2_k127_3158005_8 Protein tyrosine kinase K11912,K12132 - 2.7.11.1 0.00000000004356 74.0
DTH2_k127_3158005_9 PFAM PhnA protein K06193 - - 0.0000000197 57.0
DTH2_k127_3172870_0 UvrD/REP helicase N-terminal domain K03654 - 3.6.4.12 0.0 1581.0
DTH2_k127_3172870_1 Cation transporter/ATPase, N-terminus - - - 1.059e-312 985.0
DTH2_k127_3172870_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000001045 202.0
DTH2_k127_3172870_11 Mobile mystery protein B - - - 0.00000000000000000000000000000000000005323 145.0
DTH2_k127_3172870_12 - - - - 0.0000000000000000000000000000000001042 136.0
DTH2_k127_3172870_13 Fic/DOC family - - - 0.0000000000000000001358 92.0
DTH2_k127_3172870_14 - - - - 0.0000000000001963 76.0
DTH2_k127_3172870_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 6.185e-242 758.0
DTH2_k127_3172870_3 PFAM filamentation induced by cAMP protein Fic - - - 4.575e-207 646.0
DTH2_k127_3172870_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 496.0
DTH2_k127_3172870_5 universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 354.0
DTH2_k127_3172870_6 universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 316.0
DTH2_k127_3172870_7 import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 295.0
DTH2_k127_3172870_8 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002291 267.0
DTH2_k127_3172870_9 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003108 258.0
DTH2_k127_3216988_0 Cytochrome b(N-terminal)/b6/petB - - - 0.0 1094.0
DTH2_k127_3216988_1 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 0.0 1016.0
DTH2_k127_3216988_10 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 319.0
DTH2_k127_3216988_11 nuclease - - - 0.00000000000000000000000000000000000000000004994 171.0
DTH2_k127_3216988_12 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000006864 151.0
DTH2_k127_3216988_13 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000001363 138.0
DTH2_k127_3216988_14 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000004912 100.0
DTH2_k127_3216988_15 antisigma factor binding K04749 - - 0.00000000000000000004452 96.0
DTH2_k127_3216988_16 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.000000000000000002588 100.0
DTH2_k127_3216988_17 - - - - 0.0000000000000003162 91.0
DTH2_k127_3216988_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 2.924e-244 766.0
DTH2_k127_3216988_3 (GMC) oxidoreductase K00108 - 1.1.99.1 2.773e-231 749.0
DTH2_k127_3216988_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.642e-212 666.0
DTH2_k127_3216988_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 470.0
DTH2_k127_3216988_6 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 417.0
DTH2_k127_3216988_7 Beta-lactamase K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 388.0
DTH2_k127_3216988_8 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 370.0
DTH2_k127_3216988_9 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 327.0
DTH2_k127_3222801_0 Acyl-CoA dehydrogenase N terminal K20035 - - 1.139e-300 932.0
DTH2_k127_3222801_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 525.0
DTH2_k127_3222801_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 422.0
DTH2_k127_3222801_3 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 344.0
DTH2_k127_3222801_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
DTH2_k127_3222801_5 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000002973 216.0
DTH2_k127_3222801_6 Protein of unknown function DUF126 K09123,K09128 - - 0.000000000000000000000000000000000000000000000000000193 190.0
DTH2_k127_3222801_7 DSBA Oxidoreductase - - - 0.000000000000000000000000000000000000000000001336 173.0
DTH2_k127_3222801_8 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000002395 79.0
DTH2_k127_323035_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1432.0
DTH2_k127_323035_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1397.0
DTH2_k127_323035_10 mechanosensitive ion channel K03442,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 452.0
DTH2_k127_323035_11 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 401.0
DTH2_k127_323035_12 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 288.0
DTH2_k127_323035_13 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 310.0
DTH2_k127_323035_14 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000001165 210.0
DTH2_k127_323035_15 - - - - 0.000000000000000000000000000000000000000000000000000000001371 213.0
DTH2_k127_323035_16 Psort location Cytoplasmic, score K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000001329 175.0
DTH2_k127_323035_17 - - - - 0.000000000000000000003422 104.0
DTH2_k127_323035_19 EF-hand, calcium binding motif - - - 0.0000002025 60.0
DTH2_k127_323035_2 SNARE associated Golgi protein - - - 0.0 1160.0
DTH2_k127_323035_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1154.0
DTH2_k127_323035_4 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 2.124e-238 741.0
DTH2_k127_323035_5 CoA-transferase family III - - - 9.852e-214 668.0
DTH2_k127_323035_6 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 2.755e-202 639.0
DTH2_k127_323035_7 sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 558.0
DTH2_k127_323035_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 507.0
DTH2_k127_323035_9 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 467.0
DTH2_k127_3238920_0 Part of a membrane complex involved in electron transport K03615 - - 1.407e-235 741.0
DTH2_k127_3238920_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 433.0
DTH2_k127_3238920_2 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 330.0
DTH2_k127_3238920_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 318.0
DTH2_k127_3238920_4 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
DTH2_k127_3238920_5 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001436 264.0
DTH2_k127_3238920_6 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000384 246.0
DTH2_k127_3238920_7 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000000000000002002 207.0
DTH2_k127_3238920_8 ATPase (AAA - - - 0.0000000000000000000000000000000000000000000000000000001415 196.0
DTH2_k127_3240480_0 argininosuccinate lyase K01755 - 4.3.2.1 3.44e-240 748.0
DTH2_k127_3240480_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 570.0
DTH2_k127_3240480_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005963 273.0
DTH2_k127_3240480_11 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000004337 248.0
DTH2_k127_3240480_12 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000000009004 197.0
DTH2_k127_3240480_13 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000002617 172.0
DTH2_k127_3240480_14 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000009128 119.0
DTH2_k127_3240480_15 - K11275 - - 0.0000000000000002072 83.0
DTH2_k127_3240480_16 Aminotransferase - - - 0.000000000000001861 77.0
DTH2_k127_3240480_17 - K06950 - - 0.000000000009346 68.0
DTH2_k127_3240480_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 566.0
DTH2_k127_3240480_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 546.0
DTH2_k127_3240480_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 460.0
DTH2_k127_3240480_5 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 430.0
DTH2_k127_3240480_6 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 415.0
DTH2_k127_3240480_7 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 319.0
DTH2_k127_3240480_8 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 326.0
DTH2_k127_3240480_9 Ami_2 K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
DTH2_k127_3273136_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 413.0
DTH2_k127_3273136_1 peptidase, M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
DTH2_k127_3273136_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000002738 210.0
DTH2_k127_3273136_3 transcriptional - - - 0.000000000000000000000000000000000000000000000001026 182.0
DTH2_k127_3273136_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000002385 158.0
DTH2_k127_3273136_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000006692 143.0
DTH2_k127_3273136_6 Bacterial SH3 domain - - - 0.00000000000000001493 84.0
DTH2_k127_3314080_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 604.0
DTH2_k127_3314080_1 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 342.0
DTH2_k127_3314080_2 Carboxylesterase family K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006981 278.0
DTH2_k127_3314080_3 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000001808 243.0
DTH2_k127_3314080_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000009919 178.0
DTH2_k127_3314080_5 Aldo keto reductase - - - 0.000000000000000000000006456 102.0
DTH2_k127_3347006_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0 1436.0
DTH2_k127_3347006_1 Cytochrome c K02198 - - 5.175e-302 945.0
DTH2_k127_3347006_10 protein conserved in bacteria K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 301.0
DTH2_k127_3347006_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 302.0
DTH2_k127_3347006_12 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 301.0
DTH2_k127_3347006_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001973 274.0
DTH2_k127_3347006_14 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000008086 256.0
DTH2_k127_3347006_15 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002413 249.0
DTH2_k127_3347006_16 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000002543 231.0
DTH2_k127_3347006_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000001221 207.0
DTH2_k127_3347006_18 ferredoxin-type protein napF K02572 - - 0.00000000000000000000000000000000000000000000000000116 188.0
DTH2_k127_3347006_19 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000005738 169.0
DTH2_k127_3347006_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051,K15576 - - 1.184e-209 659.0
DTH2_k127_3347006_20 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000003621 156.0
DTH2_k127_3347006_21 - - - - 0.0000000000000000000000000000000000002929 144.0
DTH2_k127_3347006_22 - - - - 0.00000000000000000000000000000000001955 151.0
DTH2_k127_3347006_23 - K06039 - - 0.0000000000000000000000000000003459 126.0
DTH2_k127_3347006_24 Glycine-zipper domain - - - 0.0000000000000000000000000001267 126.0
DTH2_k127_3347006_25 Copper resistance protein D - - - 0.0000000000000000000000000003285 120.0
DTH2_k127_3347006_26 NapD protein K02570 - - 0.000000000000000000005684 95.0
DTH2_k127_3347006_27 - - - - 0.000000000000000000462 94.0
DTH2_k127_3347006_28 - - - - 0.00000000000000001656 91.0
DTH2_k127_3347006_29 sequence-specific DNA binding - - - 0.000000000007962 67.0
DTH2_k127_3347006_3 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 549.0
DTH2_k127_3347006_30 Heme exporter protein D (CcmD) K02196 - - 0.0001207 47.0
DTH2_k127_3347006_4 4Fe-4S dicluster domain K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 435.0
DTH2_k127_3347006_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 426.0
DTH2_k127_3347006_6 4Fe-4S binding domain K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 422.0
DTH2_k127_3347006_7 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 410.0
DTH2_k127_3347006_8 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 413.0
DTH2_k127_3347006_9 oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 359.0
DTH2_k127_3351996_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1064.0
DTH2_k127_3351996_1 Participates in both transcription termination and antitermination K02600 - - 1.366e-238 745.0
DTH2_k127_3351996_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 483.0
DTH2_k127_3351996_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 356.0
DTH2_k127_3351996_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 320.0
DTH2_k127_3351996_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000006811 175.0
DTH2_k127_3351996_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000002224 145.0
DTH2_k127_3351996_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000001567 139.0
DTH2_k127_3392889_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 402.0
DTH2_k127_3392889_1 pyridine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 402.0
DTH2_k127_3392889_2 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000000000000000000000003411 215.0
DTH2_k127_3392889_3 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000001605 185.0
DTH2_k127_3392889_4 PEP-CTERM motif - - - 0.00000009772 61.0
DTH2_k127_3395104_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 600.0
DTH2_k127_3395104_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000001062 212.0
DTH2_k127_3395104_2 PFAM Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000001468 200.0
DTH2_k127_3395104_3 methyltransferase activity - - - 0.000000000000000000000008179 112.0
DTH2_k127_3395104_4 Methyltransferase domain - - - 0.00000000000000003571 89.0
DTH2_k127_3399741_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.571e-284 882.0
DTH2_k127_3399741_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 299.0
DTH2_k127_3399741_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 287.0
DTH2_k127_3399741_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 284.0
DTH2_k127_3399741_4 redox protein, regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000001516 230.0
DTH2_k127_3399741_5 CNP1-like family - - - 0.000000000000000000000000000000000001337 149.0
DTH2_k127_3420097_0 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 353.0
DTH2_k127_3420097_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006314 283.0
DTH2_k127_3420097_2 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000454 278.0
DTH2_k127_3420097_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000009467 234.0
DTH2_k127_3420097_4 Transmembrane anti-sigma factor - - - 0.0000000000000002907 82.0
DTH2_k127_3420097_5 Cysteine-rich CWC - - - 0.000000000001785 70.0
DTH2_k127_3434320_0 Cytochrome c bacterial - - - 8.259e-258 803.0
DTH2_k127_3434320_1 - K07112 - - 8.147e-212 664.0
DTH2_k127_3434320_2 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 330.0
DTH2_k127_3434320_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001472 273.0
DTH2_k127_3434320_4 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
DTH2_k127_3434320_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000002696 165.0
DTH2_k127_3434320_7 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000003019 154.0
DTH2_k127_3434320_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000005806 130.0
DTH2_k127_3434320_9 - - - - 0.0000000000000000006716 94.0
DTH2_k127_3458516_0 Energy production and conversion K09181 - - 5.835e-317 994.0
DTH2_k127_3458516_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 3.268e-201 642.0
DTH2_k127_3458516_10 - - - - 0.000000000000000000003768 109.0
DTH2_k127_3458516_11 Membrane fusogenic activity K09806 - - 0.0000000000000000001386 97.0
DTH2_k127_3458516_12 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000001567 81.0
DTH2_k127_3458516_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 490.0
DTH2_k127_3458516_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 339.0
DTH2_k127_3458516_4 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 329.0
DTH2_k127_3458516_5 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 331.0
DTH2_k127_3458516_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000655 272.0
DTH2_k127_3458516_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000007793 218.0
DTH2_k127_3458516_8 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000284 180.0
DTH2_k127_3458516_9 cell division protein - - - 0.0000000000000000000000000000000000000002022 159.0
DTH2_k127_3477665_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.269e-220 690.0
DTH2_k127_3477665_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 379.0
DTH2_k127_3477665_2 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 320.0
DTH2_k127_3477665_3 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000000000000003189 142.0
DTH2_k127_3477665_4 Crp Fnr family transcriptional regulator K21563 - - 0.00004835 51.0
DTH2_k127_3526106_0 malic enzyme K00027,K00029 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40 0.0 1037.0
DTH2_k127_3526106_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1030.0
DTH2_k127_3526106_10 enzyme of heme biosynthesis K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 318.0
DTH2_k127_3526106_11 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 302.0
DTH2_k127_3526106_12 Nudix N-terminal K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008773 276.0
DTH2_k127_3526106_13 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004054 276.0
DTH2_k127_3526106_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000003792 241.0
DTH2_k127_3526106_15 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000000255 71.0
DTH2_k127_3526106_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 510.0
DTH2_k127_3526106_3 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 509.0
DTH2_k127_3526106_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 498.0
DTH2_k127_3526106_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 479.0
DTH2_k127_3526106_6 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 449.0
DTH2_k127_3526106_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 422.0
DTH2_k127_3526106_8 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 363.0
DTH2_k127_3526106_9 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 320.0
DTH2_k127_354437_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 520.0
DTH2_k127_354437_1 PFAM Nitrile hydratase alpha K01721,K20762 - 3.5.5.8,4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 391.0
DTH2_k127_354437_10 Nitrile hydratase beta subunit K20761 - 3.5.5.8 0.000000000000000000000000000000000000000000000000000163 191.0
DTH2_k127_354437_11 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000001979 161.0
DTH2_k127_354437_12 - - - - 0.0000000000000000000000000000000000000001368 154.0
DTH2_k127_354437_13 - - - - 0.00000000000000000000001926 104.0
DTH2_k127_354437_2 Phenazine biosynthesis protein phzf family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 389.0
DTH2_k127_354437_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 382.0
DTH2_k127_354437_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 377.0
DTH2_k127_354437_5 Pfam ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 366.0
DTH2_k127_354437_6 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 364.0
DTH2_k127_354437_7 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 304.0
DTH2_k127_354437_8 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 286.0
DTH2_k127_354437_9 Cyanate lyase C-terminal domain, Cyanate hydratase K01725 - 4.2.1.104 0.000000000000000000000000000000000000000000000000000000000000000000136 232.0
DTH2_k127_356882_0 Molydopterin dinucleotide binding domain K18361 - 1.17.5.1,3.1.2.25 0.0 1530.0
DTH2_k127_356882_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K18356 - 1.2.1.58 3.747e-249 775.0
DTH2_k127_356882_10 4Fe-4S binding domain K18358 - 1.2.1.58 0.0000000000000000000000000000000000000000000000000000000479 201.0
DTH2_k127_356882_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000134 172.0
DTH2_k127_356882_12 C4-dicarboxylate transport system - - - 0.000000000000000000000000000000000000000000003706 166.0
DTH2_k127_356882_2 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 4.535e-236 736.0
DTH2_k127_356882_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.177e-223 700.0
DTH2_k127_356882_4 Pyridine nucleotide-disulphide oxidoreductase K18359 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 620.0
DTH2_k127_356882_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 422.0
DTH2_k127_356882_6 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 392.0
DTH2_k127_356882_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K18357 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 317.0
DTH2_k127_356882_8 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 300.0
DTH2_k127_356882_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.000000000000000000000000000000000000000000000000000000000000000002829 229.0
DTH2_k127_3648788_0 Acyl-CoA dehydrogenase N terminal K20035 - - 4.922e-268 836.0
DTH2_k127_3648788_1 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 460.0
DTH2_k127_3648788_2 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 416.0
DTH2_k127_3648788_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001702 238.0
DTH2_k127_3648788_4 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000002972 238.0
DTH2_k127_3648788_5 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.00000000000000000000000000000004565 124.0
DTH2_k127_3734057_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1103.0
DTH2_k127_3734057_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 6.231e-200 638.0
DTH2_k127_3734057_2 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 417.0
DTH2_k127_3734057_3 - - - - 0.000000000000000000000000000000000000000000001953 169.0
DTH2_k127_3734057_4 AcrB/AcrD/AcrF family K07239 - - 0.000000000000000000000000000000000000005489 145.0
DTH2_k127_3734057_5 Copper binding periplasmic protein CusF - - - 0.0000000000000000001713 92.0
DTH2_k127_376188_0 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 486.0
DTH2_k127_376188_1 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 353.0
DTH2_k127_376188_2 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 330.0
DTH2_k127_376188_3 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007325 246.0
DTH2_k127_376188_4 Acyltransferase family K16568 - - 0.0000000000000000000000000000000000000000000000000000002006 208.0
DTH2_k127_376188_5 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000008356 187.0
DTH2_k127_376188_6 Adenylylsulphate kinase K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.0003525 44.0
DTH2_k127_3791393_0 acetolactate synthase large subunit K01576,K01652 - 2.2.1.6,4.1.1.7 1.441e-202 643.0
DTH2_k127_3791393_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 303.0
DTH2_k127_3791393_2 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 290.0
DTH2_k127_3791393_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002135 271.0
DTH2_k127_3791393_4 Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000001759 240.0
DTH2_k127_3791393_5 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001832 240.0
DTH2_k127_3791393_6 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000009238 235.0
DTH2_k127_3791393_8 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.00000000000000000000000008619 110.0
DTH2_k127_3811269_0 CoA binding domain - - - 0.0 1019.0
DTH2_k127_3811269_1 GTP-binding protein TypA K06207 - - 0.0 1010.0
DTH2_k127_3811269_10 Thioesterase - - - 0.000009598 50.0
DTH2_k127_3811269_12 PFAM Integrase catalytic - - - 0.0007365 43.0
DTH2_k127_3811269_2 ATP-grasp domain - - - 7.751e-229 735.0
DTH2_k127_3811269_3 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 362.0
DTH2_k127_3811269_4 Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione K03396 - 4.4.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 311.0
DTH2_k127_3811269_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
DTH2_k127_3811269_6 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000003849 228.0
DTH2_k127_3811269_7 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000006957 200.0
DTH2_k127_3811269_8 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000001578 136.0
DTH2_k127_3811269_9 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000394 66.0
DTH2_k127_3827843_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 1.419e-212 670.0
DTH2_k127_3827843_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 415.0
DTH2_k127_3827843_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001733 275.0
DTH2_k127_3827843_3 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000002038 218.0
DTH2_k127_3827843_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000004156 176.0
DTH2_k127_3827843_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000001728 147.0
DTH2_k127_3878791_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - 0.0 1123.0
DTH2_k127_3878791_1 GAF domain - - - 6.747e-266 828.0
DTH2_k127_3878791_2 repeat-containing protein - - - 2.622e-207 677.0
DTH2_k127_3878791_3 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 372.0
DTH2_k127_3878791_4 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 296.0
DTH2_k127_3878791_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003819 299.0
DTH2_k127_3878791_6 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000002691 143.0
DTH2_k127_3878791_7 Glycosyl transferase family 41 - - - 0.0002922 49.0
DTH2_k127_3886350_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.7e-316 980.0
DTH2_k127_3886350_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 6.875e-312 964.0
DTH2_k127_3886350_10 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 601.0
DTH2_k127_3886350_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 471.0
DTH2_k127_3886350_12 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 466.0
DTH2_k127_3886350_13 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 445.0
DTH2_k127_3886350_14 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 436.0
DTH2_k127_3886350_15 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 434.0
DTH2_k127_3886350_16 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 429.0
DTH2_k127_3886350_17 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 428.0
DTH2_k127_3886350_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 381.0
DTH2_k127_3886350_19 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 368.0
DTH2_k127_3886350_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 5.65e-310 955.0
DTH2_k127_3886350_20 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 359.0
DTH2_k127_3886350_21 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 333.0
DTH2_k127_3886350_22 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 314.0
DTH2_k127_3886350_23 belongs to the wrba family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 296.0
DTH2_k127_3886350_24 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 283.0
DTH2_k127_3886350_25 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 282.0
DTH2_k127_3886350_26 Adenylylsulphate kinase K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001004 280.0
DTH2_k127_3886350_27 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001487 284.0
DTH2_k127_3886350_28 Acetolactate synthase small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
DTH2_k127_3886350_29 PFAM Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001747 269.0
DTH2_k127_3886350_3 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 3.638e-297 919.0
DTH2_k127_3886350_30 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009904 264.0
DTH2_k127_3886350_31 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005928 261.0
DTH2_k127_3886350_32 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000394 228.0
DTH2_k127_3886350_33 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
DTH2_k127_3886350_34 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000009509 216.0
DTH2_k127_3886350_35 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000003291 207.0
DTH2_k127_3886350_36 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000004388 188.0
DTH2_k127_3886350_37 membrane protein domain - - - 0.000000000000000000000000000000000000000000000000003666 184.0
DTH2_k127_3886350_38 - - - - 0.000000000000000000000000000000000000000000000000004535 200.0
DTH2_k127_3886350_39 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002171 161.0
DTH2_k127_3886350_4 Transport of potassium into the cell K03549 - - 9.674e-263 828.0
DTH2_k127_3886350_40 cytochrome - - - 0.000000000000000000000000000000000000000007065 164.0
DTH2_k127_3886350_41 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000001076 155.0
DTH2_k127_3886350_42 preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000000002347 158.0
DTH2_k127_3886350_43 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000004209 150.0
DTH2_k127_3886350_44 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000005607 141.0
DTH2_k127_3886350_45 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000006565 141.0
DTH2_k127_3886350_46 Protein of unknown function (DUF3106) - - - 0.00000000000000000000000000000000007011 140.0
DTH2_k127_3886350_47 Rhodanese Homology Domain - - - 0.000000000000000000000000000000001983 136.0
DTH2_k127_3886350_48 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000000007512 131.0
DTH2_k127_3886350_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.011e-258 805.0
DTH2_k127_3886350_50 Protein of unknown function (DUF3619) - - - 0.000000000000000009431 89.0
DTH2_k127_3886350_52 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000003587 82.0
DTH2_k127_3886350_53 Fic/DOC family N-terminal - - - 0.000000004935 59.0
DTH2_k127_3886350_54 - - - - 0.00000098 55.0
DTH2_k127_3886350_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 9.628e-246 767.0
DTH2_k127_3886350_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.427e-228 715.0
DTH2_k127_3886350_8 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 1.699e-203 640.0
DTH2_k127_3886350_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 597.0
DTH2_k127_3896714_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 3.912e-280 876.0
DTH2_k127_3896714_1 Isocitrate/isopropylmalate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 4.203e-233 726.0
DTH2_k127_3896714_10 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000000000002339 187.0
DTH2_k127_3896714_11 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000003203 185.0
DTH2_k127_3896714_12 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000003612 164.0
DTH2_k127_3896714_13 Cold shock K03704 - - 0.0000000000000000000000000000000001211 132.0
DTH2_k127_3896714_14 Belongs to the UPF0434 family K09791 - - 0.000000000000000000001383 95.0
DTH2_k127_3896714_15 SlyX K03745 - - 0.00000000000005449 83.0
DTH2_k127_3896714_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 3.09e-200 628.0
DTH2_k127_3896714_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
DTH2_k127_3896714_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 365.0
DTH2_k127_3896714_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 355.0
DTH2_k127_3896714_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 335.0
DTH2_k127_3896714_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 338.0
DTH2_k127_3896714_8 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 297.0
DTH2_k127_3896714_9 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003291 277.0
DTH2_k127_3930095_0 Periplasmic copper-binding protein (NosD) K07218 - - 1.997e-208 656.0
DTH2_k127_3930095_1 4Fe-4S binding domain K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 548.0
DTH2_k127_3930095_10 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000006689 185.0
DTH2_k127_3930095_11 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000006956 170.0
DTH2_k127_3930095_12 - - - - 0.000000000002649 74.0
DTH2_k127_3930095_13 NAD(P)-binding Rossmann-like domain - - - 0.000000000003539 69.0
DTH2_k127_3930095_2 4Fe-4S binding domain K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 483.0
DTH2_k127_3930095_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 464.0
DTH2_k127_3930095_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 442.0
DTH2_k127_3930095_5 Periplasmic copper-binding K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 419.0
DTH2_k127_3930095_6 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 307.0
DTH2_k127_3930095_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 307.0
DTH2_k127_3930095_8 Sodium symporter K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006389 257.0
DTH2_k127_3930095_9 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000003743 205.0
DTH2_k127_3964316_0 Periplasmic binding protein K01999 - - 4.421e-238 742.0
DTH2_k127_3964316_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 575.0
DTH2_k127_3964316_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 566.0
DTH2_k127_3964316_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 535.0
DTH2_k127_3964316_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 456.0
DTH2_k127_3964316_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 419.0
DTH2_k127_3994164_0 von Willebrand factor, type A - - - 1.492e-279 859.0
DTH2_k127_3994164_1 von Willebrand factor, type A - - - 1.612e-218 679.0
DTH2_k127_3994164_2 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 524.0
DTH2_k127_3994164_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 501.0
DTH2_k127_3994164_4 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 467.0
DTH2_k127_3994164_5 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 359.0
DTH2_k127_3994164_6 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000188 253.0
DTH2_k127_3994164_7 ribulose bisphosphate carboxylase, small K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000004387 250.0
DTH2_k127_3994164_8 - - - - 0.000000000000000000000000000000000000000000000000000000005076 199.0
DTH2_k127_3994164_9 - - - - 0.000000000000000000000000000000000000001862 151.0
DTH2_k127_3999069_0 Diguanylate cyclase - - - 4.655e-246 771.0
DTH2_k127_3999069_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 294.0
DTH2_k127_3999069_2 cheY-homologous receiver domain K02485 - - 0.00000000000000000341 88.0
DTH2_k127_3999069_3 Phosphoribulokinase K00855 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19 0.00000000009461 62.0
DTH2_k127_3999069_4 cheY-homologous receiver domain K02485 - - 0.00000000889 58.0
DTH2_k127_4002896_0 Protein of unknown function, DUF255 K06888 - - 9.041e-249 787.0
DTH2_k127_4002896_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 435.0
DTH2_k127_4002896_2 response regulator K03413 - - 0.000000000000000000000000000000000000000000000000000000007046 201.0
DTH2_k127_4002896_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000006733 196.0
DTH2_k127_4002896_4 - - - - 0.000000000000000000000000000000000000000000003667 168.0
DTH2_k127_4002896_5 PFAM DsrE DsrF-like family - - - 0.000000000000000000000000000000002378 136.0
DTH2_k127_4002896_6 Cytochrome c K08738 - - 0.00000000000000000000000000000008983 128.0
DTH2_k127_4002896_7 thiosulfate sulfurtransferase activity - - - 0.00000003873 55.0
DTH2_k127_4004243_0 amine oxidase - - - 1.132e-265 825.0
DTH2_k127_4004243_1 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 588.0
DTH2_k127_4004243_10 - - - - 0.000000000000000000001401 109.0
DTH2_k127_4004243_11 Glycosyltransferase like family 2 - - - 0.000000000000000007139 90.0
DTH2_k127_4004243_12 GtrA-like protein - - - 0.000000000000007677 79.0
DTH2_k127_4004243_13 Domain of unknown function (DUF4143) - - - 0.000002125 55.0
DTH2_k127_4004243_2 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 545.0
DTH2_k127_4004243_3 ATPase, AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 421.0
DTH2_k127_4004243_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 365.0
DTH2_k127_4004243_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 323.0
DTH2_k127_4004243_6 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 304.0
DTH2_k127_4004243_7 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000146 263.0
DTH2_k127_4004243_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000002851 227.0
DTH2_k127_4004243_9 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000008704 180.0
DTH2_k127_4010467_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 2.775e-208 655.0
DTH2_k127_4010467_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 599.0
DTH2_k127_4010467_10 TonB C terminal K03646 - - 0.0000000000000000000000000000000000000000000000000001974 194.0
DTH2_k127_4010467_11 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000002015 173.0
DTH2_k127_4010467_12 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000002404 171.0
DTH2_k127_4010467_13 Glycosyltransferase sugar-binding region containing DXD motif - - - 0.00000000000002488 79.0
DTH2_k127_4010467_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 400.0
DTH2_k127_4010467_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 319.0
DTH2_k127_4010467_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 295.0
DTH2_k127_4010467_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 299.0
DTH2_k127_4010467_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002726 264.0
DTH2_k127_4010467_7 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000258 228.0
DTH2_k127_4010467_8 OmpA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000736 213.0
DTH2_k127_4010467_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000001537 200.0
DTH2_k127_4037873_0 Belongs to the thiolase family - - - 7.436e-232 722.0
DTH2_k127_4037873_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 1.545e-198 632.0
DTH2_k127_4037873_10 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000005931 67.0
DTH2_k127_4037873_2 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 522.0
DTH2_k127_4037873_3 Protein of unknown function (DUF1329) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 496.0
DTH2_k127_4037873_4 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 444.0
DTH2_k127_4037873_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
DTH2_k127_4037873_6 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 322.0
DTH2_k127_4037873_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 306.0
DTH2_k127_4037873_8 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000002471 222.0
DTH2_k127_4037873_9 Protein of unknown function DUF126 K09123,K09128 - - 0.000000000000000000000000000000000000000000000000000004053 193.0
DTH2_k127_4047732_0 Inorganic ion transport and metabolism K03319 - - 3.741e-195 620.0
DTH2_k127_4047732_1 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 473.0
DTH2_k127_4047732_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 467.0
DTH2_k127_4047732_3 - - - - 0.000000000000000000000000000000000001654 146.0
DTH2_k127_4047732_4 - - - - 0.0000000001533 62.0
DTH2_k127_4047732_5 - - - - 0.000000005491 63.0
DTH2_k127_4098833_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 608.0
DTH2_k127_4098833_1 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 432.0
DTH2_k127_4098833_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 415.0
DTH2_k127_4098833_3 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 407.0
DTH2_k127_4098833_4 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000005016 221.0
DTH2_k127_4098833_5 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000008806 154.0
DTH2_k127_4098833_6 Helix-turn-helix domain - - - 0.00000000000000000000000001075 113.0
DTH2_k127_4098833_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000001482 117.0
DTH2_k127_4098833_8 addiction module antidote protein, HigA family K21498 GO:0008150,GO:0009636,GO:0042221,GO:0050896 - 0.0000000000000000001207 94.0
DTH2_k127_4180618_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.0 1353.0
DTH2_k127_4180618_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.168e-241 751.0
DTH2_k127_4180618_10 Dodecin K09165 - - 0.00000000000000000000000966 104.0
DTH2_k127_4180618_11 Pyridoxamine 5'-phosphate oxidase - - - 0.0001053 53.0
DTH2_k127_4180618_2 DNA RNA helicase - - - 3.405e-227 723.0
DTH2_k127_4180618_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 6.745e-196 620.0
DTH2_k127_4180618_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 316.0
DTH2_k127_4180618_5 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 259.0
DTH2_k127_4180618_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000006388 199.0
DTH2_k127_4180618_7 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000008208 189.0
DTH2_k127_4180618_8 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.0000000000000000000000000000000000342 139.0
DTH2_k127_4180618_9 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.0000000000000000000000000000002968 124.0
DTH2_k127_4232274_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 573.0
DTH2_k127_4232274_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 295.0
DTH2_k127_4232274_2 SapC - - - 0.0000000000000000000000000000000000000000000000000000000000000001659 229.0
DTH2_k127_4232274_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000184 116.0
DTH2_k127_426099_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2524.0
DTH2_k127_426099_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1013.0
DTH2_k127_426099_10 PFAM pentapeptide repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 340.0
DTH2_k127_426099_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 328.0
DTH2_k127_426099_12 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 330.0
DTH2_k127_426099_13 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 316.0
DTH2_k127_426099_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005523 247.0
DTH2_k127_426099_15 FMN_bind K03612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000105 257.0
DTH2_k127_426099_16 protein domain associated with - - - 0.000000000000000000000000000000000000000000003147 167.0
DTH2_k127_426099_17 - - - - 0.000000000000000000000000004404 118.0
DTH2_k127_426099_18 histidine kinase HAMP region domain protein K03406,K07216 - - 0.000000000000000001402 91.0
DTH2_k127_426099_19 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000002311 73.0
DTH2_k127_426099_2 Part of a membrane complex involved in electron transport K03615 - - 1.217e-221 694.0
DTH2_k127_426099_20 - - - - 0.0005003 45.0
DTH2_k127_426099_3 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 600.0
DTH2_k127_426099_4 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 581.0
DTH2_k127_426099_5 Fe-S oxidoreductase K21834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 556.0
DTH2_k127_426099_6 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 469.0
DTH2_k127_426099_7 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 413.0
DTH2_k127_426099_8 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 366.0
DTH2_k127_426099_9 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 363.0
DTH2_k127_4328932_0 Arsenical pump-driving ATPase K01551 - 3.6.3.16 2.249e-294 915.0
DTH2_k127_4328932_1 Predicted permease K07089 - - 5.098e-221 693.0
DTH2_k127_4328932_10 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000006338 139.0
DTH2_k127_4328932_11 Thioredoxin domain - - - 0.0000000000000000000000000002826 124.0
DTH2_k127_4328932_12 transcriptional regulator K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000001802 115.0
DTH2_k127_4328932_13 PFAM Thioredoxin K03671 - - 0.000000000000000002016 89.0
DTH2_k127_4328932_14 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000003802 94.0
DTH2_k127_4328932_2 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 601.0
DTH2_k127_4328932_3 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 504.0
DTH2_k127_4328932_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 402.0
DTH2_k127_4328932_5 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001669 264.0
DTH2_k127_4328932_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000008656 246.0
DTH2_k127_4328932_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000002397 228.0
DTH2_k127_4328932_8 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000243 213.0
DTH2_k127_4328932_9 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000000000000000000000000000000000000004432 201.0
DTH2_k127_434634_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 433.0
DTH2_k127_434634_1 transporter K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 369.0
DTH2_k127_434634_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 354.0
DTH2_k127_434634_3 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 355.0
DTH2_k127_434634_4 Transcriptional regulator of molybdate metabolism, LysR family protein - - - 0.0000000000000000000000004006 112.0
DTH2_k127_4380346_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1077.0
DTH2_k127_4380346_1 RNB K01147 - 3.1.13.1 1.235e-258 812.0
DTH2_k127_4380346_10 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000007533 244.0
DTH2_k127_4380346_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000314 197.0
DTH2_k127_4380346_12 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000007911 115.0
DTH2_k127_4380346_13 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000001817 79.0
DTH2_k127_4380346_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 7.568e-256 811.0
DTH2_k127_4380346_3 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 504.0
DTH2_k127_4380346_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 419.0
DTH2_k127_4380346_5 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 313.0
DTH2_k127_4380346_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 315.0
DTH2_k127_4380346_7 RarD protein, DMT superfamily transporter K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004318 282.0
DTH2_k127_4380346_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004591 258.0
DTH2_k127_4380346_9 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
DTH2_k127_4393974_0 epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 554.0
DTH2_k127_4393974_1 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 491.0
DTH2_k127_4393974_2 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 352.0
DTH2_k127_4393974_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000006133 63.0
DTH2_k127_441701_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 474.0
DTH2_k127_441701_1 CHAD domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 374.0
DTH2_k127_441701_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000002488 211.0
DTH2_k127_441701_3 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000000000001223 190.0
DTH2_k127_441701_4 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000000000001482 186.0
DTH2_k127_441701_5 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0001411 45.0
DTH2_k127_4437525_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.0 1523.0
DTH2_k127_4437525_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 4.958e-315 970.0
DTH2_k127_4437525_10 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 614.0
DTH2_k127_4437525_11 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 606.0
DTH2_k127_4437525_12 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 601.0
DTH2_k127_4437525_13 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 574.0
DTH2_k127_4437525_14 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 542.0
DTH2_k127_4437525_15 PFAM extracellular solute-binding protein family 1 K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 529.0
DTH2_k127_4437525_16 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 525.0
DTH2_k127_4437525_17 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 490.0
DTH2_k127_4437525_18 Reductase C-terminal K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 464.0
DTH2_k127_4437525_19 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 456.0
DTH2_k127_4437525_2 Carboxyl transferase domain - - - 8.19e-299 926.0
DTH2_k127_4437525_20 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
DTH2_k127_4437525_21 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 429.0
DTH2_k127_4437525_22 4Fe-4S binding domain K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 422.0
DTH2_k127_4437525_23 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 423.0
DTH2_k127_4437525_24 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 417.0
DTH2_k127_4437525_25 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 383.0
DTH2_k127_4437525_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 371.0
DTH2_k127_4437525_27 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit K00112 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 377.0
DTH2_k127_4437525_28 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 360.0
DTH2_k127_4437525_29 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 357.0
DTH2_k127_4437525_3 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 2.798e-269 854.0
DTH2_k127_4437525_30 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 347.0
DTH2_k127_4437525_31 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 324.0
DTH2_k127_4437525_32 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 317.0
DTH2_k127_4437525_33 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 301.0
DTH2_k127_4437525_34 transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 284.0
DTH2_k127_4437525_35 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 290.0
DTH2_k127_4437525_36 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000894 273.0
DTH2_k127_4437525_37 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006538 269.0
DTH2_k127_4437525_38 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000269 261.0
DTH2_k127_4437525_39 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000296 261.0
DTH2_k127_4437525_4 Protein of unknown function (DUF1631) - - - 3.074e-252 814.0
DTH2_k127_4437525_40 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001735 243.0
DTH2_k127_4437525_41 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000006593 239.0
DTH2_k127_4437525_42 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000002624 229.0
DTH2_k127_4437525_43 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000001652 212.0
DTH2_k127_4437525_45 Histidine kinase - - - 0.000000000000000000000000000000000000000000008002 177.0
DTH2_k127_4437525_46 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000000347 149.0
DTH2_k127_4437525_48 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000008248 134.0
DTH2_k127_4437525_49 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000004109 112.0
DTH2_k127_4437525_5 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 1.722e-219 686.0
DTH2_k127_4437525_50 - - - - 0.00000000000000000006315 94.0
DTH2_k127_4437525_51 - - - - 0.0000000000000000002219 91.0
DTH2_k127_4437525_52 Transposase zinc-ribbon domain - - - 0.000000000000000002026 87.0
DTH2_k127_4437525_53 Histidine kinase - - - 0.000000000001278 79.0
DTH2_k127_4437525_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 7.738e-210 670.0
DTH2_k127_4437525_7 - - - - 3.653e-198 623.0
DTH2_k127_4437525_8 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 620.0
DTH2_k127_4437525_9 manually curated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 612.0
DTH2_k127_452260_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.252e-253 787.0
DTH2_k127_452260_1 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 479.0
DTH2_k127_452260_2 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K18006 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 385.0
DTH2_k127_452260_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 319.0
DTH2_k127_452260_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 294.0
DTH2_k127_452260_5 maturation - - - 0.00000000000000000000000000000000000000000000000001338 184.0
DTH2_k127_4550965_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.839e-263 835.0
DTH2_k127_4550965_1 epoxide hydrolase K21159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 561.0
DTH2_k127_4550965_10 PFAM Cupin 2 conserved barrel domain protein - - - 0.0008195 42.0
DTH2_k127_4550965_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 514.0
DTH2_k127_4550965_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 357.0
DTH2_k127_4550965_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 319.0
DTH2_k127_4550965_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 303.0
DTH2_k127_4550965_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003194 245.0
DTH2_k127_4550965_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000002245 182.0
DTH2_k127_4550965_8 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000007236 132.0
DTH2_k127_4550965_9 Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000007173 67.0
DTH2_k127_455442_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1028.0
DTH2_k127_455442_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 556.0
DTH2_k127_455442_2 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 494.0
DTH2_k127_455442_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 477.0
DTH2_k127_455442_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 433.0
DTH2_k127_455442_5 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 394.0
DTH2_k127_455442_6 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 394.0
DTH2_k127_455442_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000001651 151.0
DTH2_k127_455442_8 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000002217 104.0
DTH2_k127_4585689_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 591.0
DTH2_k127_4585689_1 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 451.0
DTH2_k127_4585689_10 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000005919 235.0
DTH2_k127_4585689_11 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000004674 183.0
DTH2_k127_4585689_12 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000000009383 178.0
DTH2_k127_4585689_13 Protein of unknown function (DUF2934) - - - 0.0000005363 57.0
DTH2_k127_4585689_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 435.0
DTH2_k127_4585689_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 380.0
DTH2_k127_4585689_4 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 400.0
DTH2_k127_4585689_5 Homospermidine synthase K00808 - 2.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 345.0
DTH2_k127_4585689_6 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 332.0
DTH2_k127_4585689_7 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001178 280.0
DTH2_k127_4585689_8 Nicotinamidase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000001027 244.0
DTH2_k127_4585689_9 PFAM PEBP family protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003808 244.0
DTH2_k127_4595054_0 stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000006611 164.0
DTH2_k127_4595054_1 Belongs to the GST superfamily K03599 - - 0.000000000000000000000000000000001019 129.0
DTH2_k127_4595054_2 type I secretion membrane fusion protein, HlyD family K11003 - - 0.000000000000000002124 87.0
DTH2_k127_4595054_3 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000002777 80.0
DTH2_k127_4595054_4 ABC transporter transmembrane region K06147,K11004 - - 0.000000000000001437 79.0
DTH2_k127_4650380_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 566.0
DTH2_k127_4650380_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 447.0
DTH2_k127_4650380_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002719 250.0
DTH2_k127_4650380_3 - - - - 0.00000000000000000000000000000000005256 138.0
DTH2_k127_4660248_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 2.042e-312 966.0
DTH2_k127_4660248_1 Rod shape-determining protein MreB K03569 - - 1.499e-194 612.0
DTH2_k127_4660248_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000001919 236.0
DTH2_k127_4660248_11 shape-determining protein K03571 - - 0.00000000000000000000000000000000000000000000000000000000000004589 217.0
DTH2_k127_4660248_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000007638 136.0
DTH2_k127_4660248_13 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000009574 124.0
DTH2_k127_4660248_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 511.0
DTH2_k127_4660248_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 480.0
DTH2_k127_4660248_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 465.0
DTH2_k127_4660248_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 423.0
DTH2_k127_4660248_6 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 393.0
DTH2_k127_4660248_7 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 314.0
DTH2_k127_4660248_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 290.0
DTH2_k127_4660248_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000193 284.0
DTH2_k127_4694538_0 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 361.0
DTH2_k127_4694538_1 Stress-induced protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 321.0
DTH2_k127_4694538_2 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000003441 265.0
DTH2_k127_4694538_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000004146 238.0
DTH2_k127_4694538_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000000000000000003086 194.0
DTH2_k127_475930_0 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 633.0
DTH2_k127_475930_1 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 609.0
DTH2_k127_475930_10 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000102 148.0
DTH2_k127_475930_11 Universal stress protein family - - - 0.000000000000000000000000000412 118.0
DTH2_k127_475930_12 - - - - 0.00000000000000000006071 94.0
DTH2_k127_475930_2 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 612.0
DTH2_k127_475930_3 COG0474 Cation transport ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 586.0
DTH2_k127_475930_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 431.0
DTH2_k127_475930_5 PFAM response regulator receiver K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 306.0
DTH2_k127_475930_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000004067 252.0
DTH2_k127_475930_7 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000009232 233.0
DTH2_k127_475930_8 Nitrogen regulatory protein P-II - - - 0.00000000000000000000000000000000000000000000000005087 183.0
DTH2_k127_475930_9 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000001516 156.0
DTH2_k127_4777465_0 Type I secretion system K12536 - - 0.0 1006.0
DTH2_k127_4777465_1 type I secretion membrane fusion protein, HlyD family K02022,K12537 - - 1.177e-243 762.0
DTH2_k127_4777465_2 Outer membrane efflux protein K12538 - - 1.794e-219 688.0
DTH2_k127_4777465_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000001518 154.0
DTH2_k127_4777465_4 domain protein K20276 - - 0.000000000000000000000005111 106.0
DTH2_k127_4777465_5 Belongs to the 'phage' integrase family - - - 0.00002208 49.0
DTH2_k127_4780875_0 Belongs to the GARS family K01945 - 6.3.4.13 4.033e-210 661.0
DTH2_k127_4780875_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 582.0
DTH2_k127_4780875_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 480.0
DTH2_k127_4780875_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
DTH2_k127_4780875_4 TIGRFAM transcriptional regulator EpsA - - - 0.000000000000000000000000000000000000000000000000000000000000003454 226.0
DTH2_k127_4780875_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000005708 204.0
DTH2_k127_4780875_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000003605 160.0
DTH2_k127_4780875_7 OmpA-like transmembrane domain - - - 0.000000000000000000000009213 109.0
DTH2_k127_4780875_8 Belongs to the 'phage' integrase family - - - 0.00000000000000000000003295 104.0
DTH2_k127_4782049_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000431 258.0
DTH2_k127_4782049_1 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000002035 171.0
DTH2_k127_4782049_2 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000001802 141.0
DTH2_k127_4782049_3 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000001846 112.0
DTH2_k127_4782049_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18300 - - 0.000000000001867 73.0
DTH2_k127_483342_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1503.0
DTH2_k127_483342_1 cation transport ATPase K01533 - 3.6.3.4 1.273e-301 945.0
DTH2_k127_483342_10 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 333.0
DTH2_k127_483342_11 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 317.0
DTH2_k127_483342_12 Crp Fnr family transcriptional regulator K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008528 268.0
DTH2_k127_483342_13 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000294 224.0
DTH2_k127_483342_14 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000002524 211.0
DTH2_k127_483342_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000002799 194.0
DTH2_k127_483342_16 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000000000007177 191.0
DTH2_k127_483342_17 universal stress protein - - - 0.0000000000000000000000000000000000000000000000008863 181.0
DTH2_k127_483342_18 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000000000000000000008154 172.0
DTH2_k127_483342_19 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000346 169.0
DTH2_k127_483342_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.054e-284 877.0
DTH2_k127_483342_20 FixH family K09926 - - 0.0000000000000000000000000000000000001424 147.0
DTH2_k127_483342_21 - - - - 0.000000000000000000000006379 103.0
DTH2_k127_483342_22 cytochrome oxidase maturation protein cbb3-type - - - 0.000000000000004975 76.0
DTH2_k127_483342_23 redox protein, regulator of disulfide bond formation - - - 0.00000000000002073 79.0
DTH2_k127_483342_24 Cbb3-type cytochrome oxidase K00407 - - 0.0000000000009499 70.0
DTH2_k127_483342_3 Poly-beta-hydroxybutyrate K03821 - - 1.994e-266 832.0
DTH2_k127_483342_4 Cytochrome C oxidase accessory protein - - - 5.569e-218 685.0
DTH2_k127_483342_5 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 604.0
DTH2_k127_483342_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 452.0
DTH2_k127_483342_7 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 409.0
DTH2_k127_483342_8 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 403.0
DTH2_k127_483342_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 388.0
DTH2_k127_4861504_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.515e-198 636.0
DTH2_k127_4861504_1 Aldehyde dehydrogenase family K15515 - 1.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 538.0
DTH2_k127_4861504_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 342.0
DTH2_k127_4861504_3 Transcriptional regulator K19333 - - 0.000000000000000000000000000000000000000000000000000000000000000007952 234.0
DTH2_k127_4861504_4 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000003492 184.0
DTH2_k127_4861504_5 Conserved hypothetical protein (Lin0512_fam) - - - 0.0000000000000000000000000000000000000000000000001336 179.0
DTH2_k127_4861504_6 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000000000000007686 155.0
DTH2_k127_4861504_7 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000001094 128.0
DTH2_k127_4861504_8 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000004634 119.0
DTH2_k127_4861504_9 Cobalt chelatase, CobT subunit K09883 - 6.6.1.2 0.0000000000002127 70.0
DTH2_k127_4909749_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.33e-203 638.0
DTH2_k127_4909749_1 DNA topoisomerase III K03169 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 471.0
DTH2_k127_4909749_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 349.0
DTH2_k127_5010300_0 ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 428.0
DTH2_k127_5010300_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 390.0
DTH2_k127_5010300_2 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 302.0
DTH2_k127_5010300_3 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 242.0
DTH2_k127_5010300_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000007991 226.0
DTH2_k127_5010300_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000002386 172.0
DTH2_k127_5010300_6 BolA-like protein - - - 0.000000000000000000000000000001751 122.0
DTH2_k127_5010300_7 STAS domain K07122 - - 0.000000000000287 73.0
DTH2_k127_5090579_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.14e-301 926.0
DTH2_k127_5090579_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 7.376e-236 734.0
DTH2_k127_5090579_10 Domain of unknown function (DUF1330) - - - 0.00000000000000000007508 99.0
DTH2_k127_5090579_11 Hemerythrin K07216 - - 0.0000000000000000008844 92.0
DTH2_k127_5090579_2 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.199e-235 745.0
DTH2_k127_5090579_3 Transporter associated domain K03699 - - 8.323e-206 648.0
DTH2_k127_5090579_4 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 493.0
DTH2_k127_5090579_5 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 464.0
DTH2_k127_5090579_6 COG0564 Pseudouridylate synthases, 23S RNA-specific K06175 - 5.4.99.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 325.0
DTH2_k127_5090579_7 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 250.0
DTH2_k127_5090579_8 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000001162 179.0
DTH2_k127_5090579_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000000000000006278 147.0
DTH2_k127_5091703_0 Domain of unknown function (DUF4131) K02238 - - 2.094e-251 802.0
DTH2_k127_5091703_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 582.0
DTH2_k127_5091703_10 Protein conserved in bacteria - - - 0.00000000000000000000000000003634 124.0
DTH2_k127_5091703_11 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000003866 83.0
DTH2_k127_5091703_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 464.0
DTH2_k127_5091703_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 376.0
DTH2_k127_5091703_4 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-17-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 344.0
DTH2_k127_5091703_5 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 294.0
DTH2_k127_5091703_6 4Fe-4S dicluster domain K05796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004731 243.0
DTH2_k127_5091703_7 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000001296 242.0
DTH2_k127_5091703_8 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000004949 166.0
DTH2_k127_5091703_9 nucleic acid-binding protein contains PIN domain - - - 0.0000000000000000000000000000000000000008321 152.0
DTH2_k127_5122880_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1201.0
DTH2_k127_5122880_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.845e-288 891.0
DTH2_k127_5122880_10 - - - - 0.00000109 53.0
DTH2_k127_5122880_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.652e-283 889.0
DTH2_k127_5122880_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 539.0
DTH2_k127_5122880_4 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 366.0
DTH2_k127_5122880_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 331.0
DTH2_k127_5122880_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 321.0
DTH2_k127_5122880_7 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 318.0
DTH2_k127_5122880_8 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007006 276.0
DTH2_k127_5122880_9 - - - - 0.0000000000002435 72.0
DTH2_k127_5170201_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.977e-292 899.0
DTH2_k127_5170201_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 605.0
DTH2_k127_5170201_10 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 335.0
DTH2_k127_5170201_11 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 330.0
DTH2_k127_5170201_12 cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 284.0
DTH2_k127_5170201_13 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004091 274.0
DTH2_k127_5170201_14 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002945 277.0
DTH2_k127_5170201_15 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008283 263.0
DTH2_k127_5170201_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000003525 243.0
DTH2_k127_5170201_17 methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000816 220.0
DTH2_k127_5170201_18 Ferredoxin - - - 0.0000000000000000000000000000000000000000006128 157.0
DTH2_k127_5170201_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000003106 103.0
DTH2_k127_5170201_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 527.0
DTH2_k127_5170201_20 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000223 98.0
DTH2_k127_5170201_22 Protein of unknown function (DUF2909) - - - 0.0000000000000003878 81.0
DTH2_k127_5170201_23 - - - - 0.00000000008864 68.0
DTH2_k127_5170201_3 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 498.0
DTH2_k127_5170201_4 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 483.0
DTH2_k127_5170201_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 463.0
DTH2_k127_5170201_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 468.0
DTH2_k127_5170201_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 417.0
DTH2_k127_5170201_8 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
DTH2_k127_5170201_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 364.0
DTH2_k127_5247684_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.245e-238 742.0
DTH2_k127_5247684_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 402.0
DTH2_k127_5247684_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001734 256.0
DTH2_k127_5247684_3 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000001732 234.0
DTH2_k127_5247684_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000002077 200.0
DTH2_k127_5247684_5 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000000000000004263 152.0
DTH2_k127_5247684_7 Protein of unknown function (DUF3987) - - - 0.000000000000000002182 89.0
DTH2_k127_5250402_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.218e-266 826.0
DTH2_k127_5250402_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 6.733e-236 737.0
DTH2_k127_5250402_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009648 265.0
DTH2_k127_5250402_11 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000004121 206.0
DTH2_k127_5250402_12 colicin v production K03558 - - 0.00000000000000000000000000000000000000000001698 166.0
DTH2_k127_5250402_13 Sporulation related domain K03749 - - 0.00000000000000000000000000000000000003596 151.0
DTH2_k127_5250402_14 PFAM thioesterase superfamily protein K19222 - 3.1.2.28 0.000000000000000000000000000001375 121.0
DTH2_k127_5250402_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 597.0
DTH2_k127_5250402_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 562.0
DTH2_k127_5250402_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 502.0
DTH2_k127_5250402_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 488.0
DTH2_k127_5250402_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 388.0
DTH2_k127_5250402_7 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 350.0
DTH2_k127_5250402_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 330.0
DTH2_k127_5250402_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000823 267.0
DTH2_k127_5280925_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 4e-237 739.0
DTH2_k127_5280925_1 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 542.0
DTH2_k127_5280925_2 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 261.0
DTH2_k127_5280925_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000006972 167.0
DTH2_k127_5280925_4 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000008341 158.0
DTH2_k127_533827_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 1.401e-247 784.0
DTH2_k127_533827_1 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 317.0
DTH2_k127_533827_2 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000006957 259.0
DTH2_k127_533827_3 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000000000000000000001199 133.0
DTH2_k127_533827_4 FxsA cytoplasmic membrane protein - - - 0.00000000000000000000000000000002166 130.0
DTH2_k127_5359402_0 PFAM fumarylacetoacetate (FAA) hydrolase K18336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 357.0
DTH2_k127_5359402_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000000000000000000000000000000000000000000000000002919 188.0
DTH2_k127_5359402_2 Excalibur calcium-binding domain - - - 0.000000000000000000000000000000002128 131.0
DTH2_k127_5359402_3 Pfam Pyridoxamine 5'-phosphate - - - 0.0000000000000000000007556 101.0
DTH2_k127_5359402_4 Protein conserved in bacteria - - - 0.0000000000000000001468 91.0
DTH2_k127_5374651_0 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 584.0
DTH2_k127_5374651_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 515.0
DTH2_k127_5374651_2 - - - - 0.0007445 47.0
DTH2_k127_5432574_0 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 603.0
DTH2_k127_5432574_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 423.0
DTH2_k127_5432574_10 Thioredoxin K03671 - - 0.000000000000000000000000000000000000005344 149.0
DTH2_k127_5432574_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000004305 128.0
DTH2_k127_5432574_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 394.0
DTH2_k127_5432574_3 Aldo keto reductases, related to diketogulonate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 383.0
DTH2_k127_5432574_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 290.0
DTH2_k127_5432574_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000007483 260.0
DTH2_k127_5432574_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000003025 225.0
DTH2_k127_5432574_7 Redoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001603 222.0
DTH2_k127_5432574_8 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000001224 175.0
DTH2_k127_5432574_9 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000006325 164.0
DTH2_k127_5501437_0 MMPL family K07003 - - 1.68e-265 835.0
DTH2_k127_5501437_1 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005123 277.0
DTH2_k127_5572428_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 6.475e-287 888.0
DTH2_k127_5572428_1 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 1.561e-223 699.0
DTH2_k127_5572428_2 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 5.197e-196 613.0
DTH2_k127_5572428_3 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001012 281.0
DTH2_k127_56813_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.855e-287 887.0
DTH2_k127_56813_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.598e-270 835.0
DTH2_k127_56813_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000004508 205.0
DTH2_k127_56813_11 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000001743 203.0
DTH2_k127_56813_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000006279 203.0
DTH2_k127_56813_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000003857 193.0
DTH2_k127_56813_14 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000000000003624 164.0
DTH2_k127_56813_15 Histidine triad (HIT) - - - 0.000000000000000000000000000000000000000000834 161.0
DTH2_k127_56813_2 FAD linked oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 452.0
DTH2_k127_56813_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 453.0
DTH2_k127_56813_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 400.0
DTH2_k127_56813_5 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 410.0
DTH2_k127_56813_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 378.0
DTH2_k127_56813_7 import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005123 277.0
DTH2_k127_56813_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007183 255.0
DTH2_k127_56813_9 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000007275 222.0
DTH2_k127_5774799_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.635e-251 784.0
DTH2_k127_5774799_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.446e-236 735.0
DTH2_k127_5774799_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000003015 123.0
DTH2_k127_5774799_11 Anti sigma-E protein RseA K03597 - - 0.00000000004365 66.0
DTH2_k127_5774799_12 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K19168 - - 0.000000003952 63.0
DTH2_k127_5774799_13 Uroporphyrin-III C tetrapyrrole K07056 - 2.1.1.198 0.000001052 51.0
DTH2_k127_5774799_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 480.0
DTH2_k127_5774799_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
DTH2_k127_5774799_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 409.0
DTH2_k127_5774799_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 383.0
DTH2_k127_5774799_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 314.0
DTH2_k127_5774799_7 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
DTH2_k127_5774799_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000699 140.0
DTH2_k127_5774799_9 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000000000000001143 136.0
DTH2_k127_5812801_0 GGDEF domain containing protein - - - 1.054e-255 814.0
DTH2_k127_5812801_1 PFAM von Willebrand factor type A K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 382.0
DTH2_k127_5812801_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006943 249.0
DTH2_k127_5850494_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 419.0
DTH2_k127_5850494_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 400.0
DTH2_k127_5850494_10 DDE domain - - - 0.0000000002642 66.0
DTH2_k127_5850494_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 364.0
DTH2_k127_5850494_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001194 279.0
DTH2_k127_5850494_4 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000001461 244.0
DTH2_k127_5850494_5 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000003051 228.0
DTH2_k127_5850494_6 peptidase S16 K07157 - - 0.00000000000000000000000000000000000000000000000000000000000002811 228.0
DTH2_k127_5850494_7 NusG domain II - - - 0.00000000000000000000000000000003014 134.0
DTH2_k127_5850494_8 Gram-negative-bacterium-type cell outer membrane assembly K21572 - - 0.0000000000000000001587 97.0
DTH2_k127_5850494_9 Protein of unknown function (DUF1289) K06938 - - 0.000000000002197 68.0
DTH2_k127_5896045_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.205e-216 683.0
DTH2_k127_5896045_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 3.994e-208 652.0
DTH2_k127_5896045_10 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000004231 254.0
DTH2_k127_5896045_11 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000008301 218.0
DTH2_k127_5896045_12 ATP synthase K02115 - - 0.00000000000000000000000000000000000000000000000000008217 197.0
DTH2_k127_5896045_13 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000003389 159.0
DTH2_k127_5896045_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000003563 132.0
DTH2_k127_5896045_15 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000000003977 135.0
DTH2_k127_5896045_16 Thioredoxin domain - - - 0.00000000000000000000000000000004419 127.0
DTH2_k127_5896045_17 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000000003072 115.0
DTH2_k127_5896045_18 cytochrome - - - 0.0000000000000000000000004997 113.0
DTH2_k127_5896045_19 - - - - 0.00000000000000000000001817 106.0
DTH2_k127_5896045_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.784e-202 640.0
DTH2_k127_5896045_20 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000368 87.0
DTH2_k127_5896045_21 Cytochrome C biogenesis protein K06196 - - 0.000000000001283 73.0
DTH2_k127_5896045_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 528.0
DTH2_k127_5896045_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 402.0
DTH2_k127_5896045_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 343.0
DTH2_k127_5896045_6 Histidine kinase K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 338.0
DTH2_k127_5896045_7 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
DTH2_k127_5896045_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 290.0
DTH2_k127_5896045_9 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 260.0
DTH2_k127_5991642_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 452.0
DTH2_k127_5991642_1 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 356.0
DTH2_k127_5991642_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 316.0
DTH2_k127_5991642_3 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000142 199.0
DTH2_k127_5991642_4 Peptidase S24-like - - - 0.000000000000000000000000000000004713 134.0
DTH2_k127_5991642_5 - - - - 0.000000000000000000000000003224 119.0
DTH2_k127_5991642_6 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000000000001791 78.0
DTH2_k127_5991642_7 - - - - 0.000000002229 61.0
DTH2_k127_6028719_0 Domain of unknown function (DUF3390) K18929 - - 2.388e-221 694.0
DTH2_k127_6028719_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 5.805e-217 687.0
DTH2_k127_6028719_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 375.0
DTH2_k127_6028719_3 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 349.0
DTH2_k127_6028719_4 Thioredoxin-like K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 340.0
DTH2_k127_6028719_5 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001537 256.0
DTH2_k127_6028719_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000001477 119.0
DTH2_k127_6028719_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000001897 60.0
DTH2_k127_6035709_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 443.0
DTH2_k127_6035709_1 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 303.0
DTH2_k127_6035709_2 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000000000000004528 237.0
DTH2_k127_6035709_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000008757 235.0
DTH2_k127_6035709_4 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
DTH2_k127_6035709_5 COG0553 Superfamily II DNA RNA helicases, SNF2 family K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000009057 180.0
DTH2_k127_6048495_0 Oligopeptidase K01414 - 3.4.24.70 0.0 1040.0
DTH2_k127_6048495_1 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 1.605e-258 811.0
DTH2_k127_6048495_10 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 366.0
DTH2_k127_6048495_11 UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 355.0
DTH2_k127_6048495_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 336.0
DTH2_k127_6048495_13 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 323.0
DTH2_k127_6048495_14 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 304.0
DTH2_k127_6048495_15 Putative DNA-binding domain K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000002417 179.0
DTH2_k127_6048495_16 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000002243 126.0
DTH2_k127_6048495_17 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001433 102.0
DTH2_k127_6048495_18 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000005257 104.0
DTH2_k127_6048495_19 - - - - 0.0000000003788 63.0
DTH2_k127_6048495_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.987e-223 730.0
DTH2_k127_6048495_3 aminopeptidase K01262 - 3.4.11.9 2.756e-197 624.0
DTH2_k127_6048495_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 548.0
DTH2_k127_6048495_5 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 534.0
DTH2_k127_6048495_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 521.0
DTH2_k127_6048495_7 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 475.0
DTH2_k127_6048495_8 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 430.0
DTH2_k127_6048495_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 384.0
DTH2_k127_6311040_0 Domain of Unknown Function (DUF748) - - - 6.348e-293 933.0
DTH2_k127_6311040_1 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
DTH2_k127_6311040_2 - - - - 0.000000000000000000000000000000006661 139.0
DTH2_k127_6325_0 PFAM UMUC domain protein DNA-repair protein K03502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 383.0
DTH2_k127_6325_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
DTH2_k127_6325_2 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002768 289.0
DTH2_k127_6325_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
DTH2_k127_6325_4 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002545 229.0
DTH2_k127_6333106_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1574.0
DTH2_k127_6333106_1 membrane-associated Zn-dependent proteases 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 623.0
DTH2_k127_6333106_10 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 292.0
DTH2_k127_6333106_11 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000001311 112.0
DTH2_k127_6333106_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000008896 120.0
DTH2_k127_6333106_13 - - - - 0.00000001646 58.0
DTH2_k127_6333106_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 539.0
DTH2_k127_6333106_3 Preprotein translocase subunit SecA (ATPase, RNA helicase) K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 481.0
DTH2_k127_6333106_4 domain protein K01212,K01317,K12287,K20276 - 3.2.1.65,3.4.21.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 413.0
DTH2_k127_6333106_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 362.0
DTH2_k127_6333106_6 anthranilate K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 328.0
DTH2_k127_6333106_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 346.0
DTH2_k127_6333106_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 318.0
DTH2_k127_6333106_9 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 329.0
DTH2_k127_6414984_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1266.0
DTH2_k127_6414984_1 AMP-binding enzyme C-terminal domain - - - 4.742e-227 711.0
DTH2_k127_6414984_2 Eco57I restriction-modification methylase K07317 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 483.0
DTH2_k127_6414984_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 378.0
DTH2_k127_6414984_4 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 379.0
DTH2_k127_6414984_5 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008152 251.0
DTH2_k127_6414984_6 Protein of unknown function (DUF2782) - - - 0.000000000000000000000000000000000004848 139.0
DTH2_k127_6414984_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000216 83.0
DTH2_k127_6414984_8 - K09892 - - 0.000000002223 60.0
DTH2_k127_6424931_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1370.0
DTH2_k127_6424931_1 Nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007508 280.0
DTH2_k127_6424931_2 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000001034 183.0
DTH2_k127_6458301_0 UPF0313 protein - - - 0.0 1194.0
DTH2_k127_6458301_1 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 2.557e-241 762.0
DTH2_k127_6458301_10 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 306.0
DTH2_k127_6458301_11 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 297.0
DTH2_k127_6458301_12 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000879 290.0
DTH2_k127_6458301_13 Phasin protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001398 244.0
DTH2_k127_6458301_14 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000001088 229.0
DTH2_k127_6458301_15 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000452 203.0
DTH2_k127_6458301_16 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000001568 198.0
DTH2_k127_6458301_17 protein conserved in bacteria K11719 - - 0.000000000000000000000000001695 120.0
DTH2_k127_6458301_18 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000002713 88.0
DTH2_k127_6458301_19 - - - - 0.00000000000552 74.0
DTH2_k127_6458301_2 Putative diguanylate phosphodiesterase - - - 7.127e-212 699.0
DTH2_k127_6458301_20 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000003583 49.0
DTH2_k127_6458301_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 568.0
DTH2_k127_6458301_4 COG0436 Aspartate tyrosine aromatic aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 524.0
DTH2_k127_6458301_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000998 507.0
DTH2_k127_6458301_6 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 421.0
DTH2_k127_6458301_7 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 427.0
DTH2_k127_6458301_8 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 408.0
DTH2_k127_6458301_9 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 328.0
DTH2_k127_6502808_0 AcrB/AcrD/AcrF family K07003 - - 0.0 1070.0
DTH2_k127_6502808_1 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 1.926e-212 670.0
DTH2_k127_6502808_2 Protein of unknown function (DUF1329) - - - 8.821e-201 631.0
DTH2_k127_6502808_3 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 304.0
DTH2_k127_6502808_4 Ion channel - - - 0.0000000000000000000000004039 110.0
DTH2_k127_6560386_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 6.035e-289 906.0
DTH2_k127_6560386_1 Thioredoxin domain K03387 - - 9.298e-258 809.0
DTH2_k127_6560386_10 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 332.0
DTH2_k127_6560386_11 Lytic transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 307.0
DTH2_k127_6560386_12 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000001316 265.0
DTH2_k127_6560386_13 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000353 250.0
DTH2_k127_6560386_14 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000006524 227.0
DTH2_k127_6560386_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000003599 225.0
DTH2_k127_6560386_16 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase - - - 0.00000000000000000000000000000000000000000000000000000000003817 219.0
DTH2_k127_6560386_17 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000002355 205.0
DTH2_k127_6560386_18 Putative beta-barrel porin 2 K20920 - - 0.00000000000000000000000000000000000000000000000000006364 203.0
DTH2_k127_6560386_19 COG1596 Periplasmic protein involved in polysaccharide export K20988 - - 0.000000000000000000000000000000000000000000000000002008 190.0
DTH2_k127_6560386_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.011e-235 741.0
DTH2_k127_6560386_20 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000001979 192.0
DTH2_k127_6560386_21 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000000004847 125.0
DTH2_k127_6560386_22 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000001526 135.0
DTH2_k127_6560386_23 FecR protein - - - 0.0000000000000453 81.0
DTH2_k127_6560386_24 - - - - 0.0000000003077 72.0
DTH2_k127_6560386_3 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 4.194e-210 661.0
DTH2_k127_6560386_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.37e-205 645.0
DTH2_k127_6560386_5 TIGRFAM exopolysaccharide transport protein family K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 599.0
DTH2_k127_6560386_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 548.0
DTH2_k127_6560386_7 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 377.0
DTH2_k127_6560386_8 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 367.0
DTH2_k127_6560386_9 C-terminal domain of 1-Cys peroxiredoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 349.0
DTH2_k127_6593417_0 glucose-methanol-choline oxidoreductase K19813 - 1.1.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 426.0
DTH2_k127_6593417_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000002349 100.0
DTH2_k127_6593417_2 Cellulose biosynthesis protein BcsS - - - 0.00003038 51.0
DTH2_k127_6615464_0 Papain family cysteine protease - - - 0.0 1045.0
DTH2_k127_6615464_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.274e-299 923.0
DTH2_k127_6615464_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 353.0
DTH2_k127_6615464_3 Acyl-CoA thioesterase YciA K10806 - - 0.00000000000000000000000000000000000000000000000000003204 192.0
DTH2_k127_6615464_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000005159 169.0
DTH2_k127_6615464_5 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.0000000000000000000000000000000000001807 148.0
DTH2_k127_6615464_6 EamA-like transporter family - - - 0.00000000000000000000000000000000003218 138.0
DTH2_k127_6615464_7 - - - - 0.0000002692 60.0
DTH2_k127_6615464_8 Aconitate B N-terminal domain K01682 - 4.2.1.3,4.2.1.99 0.000002566 51.0
DTH2_k127_6627355_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 567.0
DTH2_k127_6627355_1 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 503.0
DTH2_k127_6627355_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 476.0
DTH2_k127_6627355_3 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 367.0
DTH2_k127_6627355_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 313.0
DTH2_k127_6627355_5 Domain of unknown function (DUF4824) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002706 268.0
DTH2_k127_6627355_6 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000002894 149.0
DTH2_k127_6627355_7 Short C-terminal domain - - - 0.00000001249 59.0
DTH2_k127_6627355_8 MacB-like periplasmic core domain K02004 - - 0.000001425 57.0
DTH2_k127_6629812_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 2.883e-287 889.0
DTH2_k127_6629812_1 PFAM HipA domain protein K07154 - 2.7.11.1 2.318e-236 743.0
DTH2_k127_6629812_2 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 573.0
DTH2_k127_6629812_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 492.0
DTH2_k127_6629812_4 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 349.0
DTH2_k127_6629812_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 313.0
DTH2_k127_6629812_6 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000002838 210.0
DTH2_k127_6629812_7 BON domain - - - 0.000000000000000000000000000000000000000000000000000000001934 207.0
DTH2_k127_6629812_8 regulator K15773 - - 0.00000000000000000000000001149 112.0
DTH2_k127_6640706_0 MMPL family K18138 - - 0.0 1546.0
DTH2_k127_6640706_1 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1256.0
DTH2_k127_6640706_10 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 506.0
DTH2_k127_6640706_11 phosphate K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 470.0
DTH2_k127_6640706_12 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 454.0
DTH2_k127_6640706_13 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347,K03614 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 432.0
DTH2_k127_6640706_14 Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 426.0
DTH2_k127_6640706_15 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 398.0
DTH2_k127_6640706_16 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 373.0
DTH2_k127_6640706_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 379.0
DTH2_k127_6640706_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 353.0
DTH2_k127_6640706_19 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 348.0
DTH2_k127_6640706_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1071.0
DTH2_k127_6640706_20 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 342.0
DTH2_k127_6640706_21 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001253 246.0
DTH2_k127_6640706_22 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000002994 248.0
DTH2_k127_6640706_23 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
DTH2_k127_6640706_24 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000001781 237.0
DTH2_k127_6640706_25 Efflux transporter, outer membrane factor lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000003588 241.0
DTH2_k127_6640706_26 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000001753 187.0
DTH2_k127_6640706_27 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000000002886 173.0
DTH2_k127_6640706_28 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000005932 169.0
DTH2_k127_6640706_29 Ferredoxin - - - 0.0000000000000000000000000000000000000396 143.0
DTH2_k127_6640706_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1007.0
DTH2_k127_6640706_30 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000001364 149.0
DTH2_k127_6640706_31 PIN domain - - - 0.0000000000000000000000000000003757 130.0
DTH2_k127_6640706_32 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000006272 123.0
DTH2_k127_6640706_33 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000001314 116.0
DTH2_k127_6640706_34 Transcriptional regulator K07172 - - 0.000000000000000000000000008504 114.0
DTH2_k127_6640706_35 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000004342 115.0
DTH2_k127_6640706_36 - - - - 0.000000000000001831 90.0
DTH2_k127_6640706_37 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000051 78.0
DTH2_k127_6640706_38 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000284 66.0
DTH2_k127_6640706_39 of the major facilitator superfamily - - - 0.00000009815 62.0
DTH2_k127_6640706_4 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.5e-319 987.0
DTH2_k127_6640706_40 SEC-C Motif Domain Protein - - - 0.0007872 51.0
DTH2_k127_6640706_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 4.404e-200 637.0
DTH2_k127_6640706_6 Protein of unknown function (DUF3141) - - - 4.173e-195 616.0
DTH2_k127_6640706_7 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 606.0
DTH2_k127_6640706_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 529.0
DTH2_k127_6640706_9 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 527.0
DTH2_k127_6650464_0 AcyL-CoA dehydrogenase K06445 - - 0.0 1132.0
DTH2_k127_6650464_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.467e-212 672.0
DTH2_k127_6650464_10 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 0.000000000000000000000000000000000000000001451 159.0
DTH2_k127_6650464_11 - - - - 0.000000000000000000000000000000000000000004887 161.0
DTH2_k127_6650464_12 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000001446 153.0
DTH2_k127_6650464_13 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000003926 101.0
DTH2_k127_6650464_14 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000007507 81.0
DTH2_k127_6650464_15 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022 - - 0.0000000000001128 73.0
DTH2_k127_6650464_2 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 571.0
DTH2_k127_6650464_3 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 409.0
DTH2_k127_6650464_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 383.0
DTH2_k127_6650464_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 294.0
DTH2_k127_6650464_6 similarity to GP 3192745 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
DTH2_k127_6650464_7 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000009834 218.0
DTH2_k127_6650464_8 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000148 196.0
DTH2_k127_6650464_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000006235 174.0
DTH2_k127_6664608_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1322.0
DTH2_k127_6664608_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1009.0
DTH2_k127_6664608_10 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 417.0
DTH2_k127_6664608_11 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 402.0
DTH2_k127_6664608_12 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 404.0
DTH2_k127_6664608_13 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 302.0
DTH2_k127_6664608_14 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006443 285.0
DTH2_k127_6664608_15 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003081 280.0
DTH2_k127_6664608_16 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001734 256.0
DTH2_k127_6664608_17 Protein of unknown function (DUF1415) K09941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003015 260.0
DTH2_k127_6664608_18 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000961 233.0
DTH2_k127_6664608_19 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000000000025 211.0
DTH2_k127_6664608_2 cellulose synthase K00694 - 2.4.1.12 1.415e-258 822.0
DTH2_k127_6664608_20 Phasin protein - - - 0.0000000000000000000000000000000000000000000000000004746 190.0
DTH2_k127_6664608_21 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000009569 193.0
DTH2_k127_6664608_22 chain release factor K15034 - - 0.000000000000000000000000000000000000000000000006349 178.0
DTH2_k127_6664608_23 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000002886 118.0
DTH2_k127_6664608_24 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000008327 85.0
DTH2_k127_6664608_25 ATP synthase I chain K02116 - - 0.00000000000005184 76.0
DTH2_k127_6664608_3 Belongs to the DEAD box helicase family K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 3.655e-224 703.0
DTH2_k127_6664608_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.187e-223 704.0
DTH2_k127_6664608_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.489e-202 641.0
DTH2_k127_6664608_6 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 610.0
DTH2_k127_6664608_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 580.0
DTH2_k127_6664608_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 482.0
DTH2_k127_6664608_9 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 430.0
DTH2_k127_6681355_0 Sterol-sensing domain of SREBP cleavage-activation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 577.0
DTH2_k127_6681355_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 475.0
DTH2_k127_6681355_2 Paraquat-inducible protein B K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 458.0
DTH2_k127_6681355_3 paraquat-inducible protein a K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 427.0
DTH2_k127_6681355_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 289.0
DTH2_k127_6681355_5 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.00000000000000000000000000000000000000002691 167.0
DTH2_k127_6681355_6 SNF2 family N-terminal domain - - - 0.000000000000000000000000000000000000001433 149.0
DTH2_k127_6681355_7 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000009406 113.0
DTH2_k127_6681355_8 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000002049 107.0
DTH2_k127_6681355_9 DNA polymerase involved in DNA repair K14161 - - 0.0000000000000001752 85.0
DTH2_k127_6695592_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.912e-227 708.0
DTH2_k127_6695592_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 458.0
DTH2_k127_6695592_10 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000009705 123.0
DTH2_k127_6695592_11 Transcriptional regulator - - - 0.0000000000000000000000000004645 113.0
DTH2_k127_6695592_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 398.0
DTH2_k127_6695592_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 346.0
DTH2_k127_6695592_4 acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 345.0
DTH2_k127_6695592_5 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003125 280.0
DTH2_k127_6695592_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001201 235.0
DTH2_k127_6695592_7 Transcriptional regulator K13655 - - 0.000000000000000000000000000000000000000000000000000000000000000008731 229.0
DTH2_k127_6695592_8 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000003359 183.0
DTH2_k127_6695592_9 Motility quorum-sensing regulator, toxin of MqsA K13651 - - 0.0000000000000000000000000000000000000003421 150.0
DTH2_k127_6702252_0 FtsX-like permease family K02004 - - 0.0 1081.0
DTH2_k127_6702252_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.388e-284 893.0
DTH2_k127_6702252_10 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000059 61.0
DTH2_k127_6702252_11 - - - - 0.00001217 53.0
DTH2_k127_6702252_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.518e-273 850.0
DTH2_k127_6702252_3 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 497.0
DTH2_k127_6702252_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 353.0
DTH2_k127_6702252_5 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000005228 182.0
DTH2_k127_6702252_6 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000000111 146.0
DTH2_k127_6702252_7 - - - - 0.00000000000000000000000000001791 124.0
DTH2_k127_6702252_8 iron ion homeostasis - - - 0.00000000000000000007125 91.0
DTH2_k127_6702252_9 - - - - 0.00000000000000007718 87.0
DTH2_k127_6707777_0 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0 1111.0
DTH2_k127_6707777_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 8.42e-291 900.0
DTH2_k127_6707777_2 Luciferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 524.0
DTH2_k127_6707777_3 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 374.0
DTH2_k127_6707777_4 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 292.0
DTH2_k127_6707777_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000002097 179.0
DTH2_k127_6707777_6 MaoC like domain K12405 GO:0001676,GO:0002376,GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005782,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008209,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010817,GO:0015031,GO:0015833,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016229,GO:0016491,GO:0016508,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0030258,GO:0031090,GO:0031903,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0033540,GO:0033559,GO:0033764,GO:0033865,GO:0033875,GO:0033989,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034754,GO:0035337,GO:0035383,GO:0036109,GO:0036111,GO:0036112,GO:0042445,GO:0042579,GO:0042742,GO:0042802,GO:0042803,GO:0042886,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044594,GO:0045087,GO:0045184,GO:0046394,GO:0046395,GO:0046483,GO:0046907,GO:0046983,GO:0050829,GO:0050896,GO:0051179,GO:0051186,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072662,GO:0072663,GO:0080023,GO:0098542,GO:0098588,GO:0098805,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901568,GO:1901575,GO:1901576,GO:1901615,GO:1901617 1.1.1.35,4.2.1.107,4.2.1.119 0.0000000000000000000000000000000000000117 154.0
DTH2_k127_6707777_7 Protein of unknown function (DUF1439) - - - 0.0000000000000000000000000000006303 128.0
DTH2_k127_6707777_8 - - - - 0.0000000649 64.0
DTH2_k127_6707777_9 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0001846 44.0
DTH2_k127_6750155_0 COG0480 Translation elongation factors (GTPases) K02355 - - 0.0 1075.0
DTH2_k127_6750155_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0 1030.0
DTH2_k127_6750155_10 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 394.0
DTH2_k127_6750155_11 PFAM Extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 342.0
DTH2_k127_6750155_12 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
DTH2_k127_6750155_13 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000000000000000000000000000001717 224.0
DTH2_k127_6750155_14 AcrB/AcrD/AcrF family K07239 - - 0.00000000000000000000000000000000000000000000000000000000001415 213.0
DTH2_k127_6750155_15 protein conserved in bacteria K09790 - - 0.000000000000000000000000000000000000001094 154.0
DTH2_k127_6750155_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000003703 140.0
DTH2_k127_6750155_17 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000005905 90.0
DTH2_k127_6750155_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 9.615e-226 707.0
DTH2_k127_6750155_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 585.0
DTH2_k127_6750155_4 Member of a two-component regulatory system K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 532.0
DTH2_k127_6750155_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 461.0
DTH2_k127_6750155_6 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 464.0
DTH2_k127_6750155_7 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 420.0
DTH2_k127_6750155_8 response regulator K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 392.0
DTH2_k127_6750155_9 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 397.0
DTH2_k127_6768109_0 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.0 1019.0
DTH2_k127_6768109_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 9.782e-290 899.0
DTH2_k127_6768109_10 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001108 279.0
DTH2_k127_6768109_11 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000007179 207.0
DTH2_k127_6768109_12 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000001381 156.0
DTH2_k127_6768109_13 beta-lactamase - - - 0.0000000000005343 73.0
DTH2_k127_6768109_2 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 2.907e-222 699.0
DTH2_k127_6768109_3 Belongs to the thiolase family K00626 - 2.3.1.9 1.668e-201 634.0
DTH2_k127_6768109_4 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 598.0
DTH2_k127_6768109_5 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 583.0
DTH2_k127_6768109_6 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 549.0
DTH2_k127_6768109_7 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 457.0
DTH2_k127_6768109_8 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 430.0
DTH2_k127_6768109_9 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 361.0
DTH2_k127_679188_0 Activator of aromatic catabolism - - - 6.75e-202 645.0
DTH2_k127_679188_1 Outer membrane lipoprotein-sorting protein - - - 2.197e-194 614.0
DTH2_k127_679188_2 Sh3 type 3 domain protein - - - 0.00000000001629 64.0
DTH2_k127_68616_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 4.203e-303 938.0
DTH2_k127_68616_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 5.519e-264 827.0
DTH2_k127_68616_10 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000004494 221.0
DTH2_k127_68616_11 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000002757 209.0
DTH2_k127_68616_12 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000007016 161.0
DTH2_k127_68616_13 PFAM Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000001886 115.0
DTH2_k127_68616_2 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 1.223e-247 784.0
DTH2_k127_68616_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 1.88e-199 631.0
DTH2_k127_68616_4 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 601.0
DTH2_k127_68616_5 LysR substrate binding domain K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
DTH2_k127_68616_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 321.0
DTH2_k127_68616_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 304.0
DTH2_k127_68616_8 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 299.0
DTH2_k127_68616_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000003053 254.0
DTH2_k127_6870045_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0 1019.0
DTH2_k127_6870045_1 Diguanylate cyclase - - - 3.938e-274 886.0
DTH2_k127_6870045_10 Integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008348 274.0
DTH2_k127_6870045_11 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002341 266.0
DTH2_k127_6870045_12 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 246.0
DTH2_k127_6870045_13 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004143 240.0
DTH2_k127_6870045_14 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000557 212.0
DTH2_k127_6870045_15 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000000000000000000000002705 207.0
DTH2_k127_6870045_16 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000004053 212.0
DTH2_k127_6870045_17 oxygen carrier activity K07216 - - 0.00000000000000000000000000000000000000000000002015 173.0
DTH2_k127_6870045_18 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000007249 102.0
DTH2_k127_6870045_19 HupF/HypC family K04653 - - 0.00000000000000000000133 96.0
DTH2_k127_6870045_2 fad dependent oxidoreductase K07137 - - 8.058e-256 798.0
DTH2_k127_6870045_3 Hydrogenase formation hypA family K04654 - - 3.668e-218 700.0
DTH2_k127_6870045_4 AIR synthase related protein, N-terminal domain K04655 - - 4.467e-198 620.0
DTH2_k127_6870045_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 432.0
DTH2_k127_6870045_6 Formyl transferase K19640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 411.0
DTH2_k127_6870045_7 Formyl transferase K19640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 411.0
DTH2_k127_6870045_8 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 407.0
DTH2_k127_6870045_9 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 313.0
DTH2_k127_6888553_0 TRAP transporter 4TM 12TM fusion - - - 5.741e-313 973.0
DTH2_k127_6888553_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.249e-251 797.0
DTH2_k127_6888553_2 acyl-CoA transferases carnitine dehydratase - - - 4.735e-197 620.0
DTH2_k127_6888553_3 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 456.0
DTH2_k127_6888553_4 Domain of unknown function (DUF1850) - - - 0.00000000336 70.0
DTH2_k127_6909100_0 B12 binding domain - - - 2.839e-319 979.0
DTH2_k127_6909100_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.326e-237 749.0
DTH2_k127_6909100_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 287.0
DTH2_k127_6909100_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001942 252.0
DTH2_k127_6909100_12 transcription regulator, contains HTH domain (MarR family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002565 252.0
DTH2_k127_6909100_13 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000003404 190.0
DTH2_k127_6909100_15 Phage integrase family - - - 0.000000000000001029 86.0
DTH2_k127_6909100_17 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000003965 49.0
DTH2_k127_6909100_18 - - - - 0.0001283 47.0
DTH2_k127_6909100_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 9.477e-214 670.0
DTH2_k127_6909100_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 561.0
DTH2_k127_6909100_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 505.0
DTH2_k127_6909100_5 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 502.0
DTH2_k127_6909100_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 428.0
DTH2_k127_6909100_7 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 423.0
DTH2_k127_6909100_8 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 358.0
DTH2_k127_6909100_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 315.0
DTH2_k127_6916373_0 B12 binding domain K00548 - 2.1.1.13 0.0 1686.0
DTH2_k127_6916373_1 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 603.0
DTH2_k127_6916373_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 553.0
DTH2_k127_6916373_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
DTH2_k127_6916373_4 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 322.0
DTH2_k127_6916373_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000003912 218.0
DTH2_k127_6916373_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000005032 156.0
DTH2_k127_6916373_7 Domain of unknown function (DUF1840) - - - 0.000000000000000000000002294 116.0
DTH2_k127_6916373_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000009109 93.0
DTH2_k127_6916373_9 Protein of unknown function (DUF2905) - - - 0.00000000002012 69.0
DTH2_k127_6924449_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1371.0
DTH2_k127_6924449_1 Acyl-CoA dehydrogenase N terminal - - - 0.0 1028.0
DTH2_k127_6924449_10 Belongs to the universal stress protein A family - - - 0.00000000000000000002211 96.0
DTH2_k127_6924449_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 1.353e-302 936.0
DTH2_k127_6924449_3 Fumarate reductase succinate dehydrogenase flavoprotein K07077 - - 9.565e-300 924.0
DTH2_k127_6924449_4 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 1.015e-282 877.0
DTH2_k127_6924449_5 Belongs to the thiolase family K00632 - 2.3.1.16 2.423e-223 696.0
DTH2_k127_6924449_6 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 432.0
DTH2_k127_6924449_7 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001963 278.0
DTH2_k127_6924449_8 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000208 211.0
DTH2_k127_6924449_9 - - - - 0.000000000000000000000000000000000000000000008517 177.0
DTH2_k127_6951844_0 Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 598.0
DTH2_k127_6951844_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 557.0
DTH2_k127_6951844_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 379.0
DTH2_k127_6951844_3 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000001265 238.0
DTH2_k127_7124591_0 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 405.0
DTH2_k127_7124591_1 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 383.0
DTH2_k127_7124591_2 AraC family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 368.0
DTH2_k127_7124591_3 Protein of unknown function DUF126 K09123,K09128 - - 0.0000000000000000000000000000000002593 143.0
DTH2_k127_7124591_4 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000001818 125.0
DTH2_k127_7124591_5 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.0000000000003626 76.0
DTH2_k127_7290649_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2348.0
DTH2_k127_7290649_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1488.0
DTH2_k127_7290649_10 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 455.0
DTH2_k127_7290649_11 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 432.0
DTH2_k127_7290649_12 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 424.0
DTH2_k127_7290649_13 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 408.0
DTH2_k127_7290649_14 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 413.0
DTH2_k127_7290649_15 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 404.0
DTH2_k127_7290649_16 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 387.0
DTH2_k127_7290649_17 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 379.0
DTH2_k127_7290649_18 Bacterial type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 394.0
DTH2_k127_7290649_19 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 344.0
DTH2_k127_7290649_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1094.0
DTH2_k127_7290649_20 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 303.0
DTH2_k127_7290649_21 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 291.0
DTH2_k127_7290649_22 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000232 254.0
DTH2_k127_7290649_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005763 257.0
DTH2_k127_7290649_24 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000356 241.0
DTH2_k127_7290649_25 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000000000000000000003017 206.0
DTH2_k127_7290649_26 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000009496 203.0
DTH2_k127_7290649_27 Belongs to the frataxin K06202 - - 0.00000000000000000000000000000000008677 135.0
DTH2_k127_7290649_28 pilus assembly protein PilP K02665 - - 0.0000000000000000000000000000002196 130.0
DTH2_k127_7290649_29 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000005777 118.0
DTH2_k127_7290649_3 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 4.003e-261 812.0
DTH2_k127_7290649_30 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.0000000000000000001856 98.0
DTH2_k127_7290649_31 - - - - 0.0000000000001665 77.0
DTH2_k127_7290649_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 6.471e-205 646.0
DTH2_k127_7290649_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 589.0
DTH2_k127_7290649_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 574.0
DTH2_k127_7290649_7 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 562.0
DTH2_k127_7290649_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 495.0
DTH2_k127_7290649_9 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 462.0
DTH2_k127_7303846_0 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002373 284.0
DTH2_k127_7303846_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000002803 221.0
DTH2_k127_7303846_2 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000003014 228.0
DTH2_k127_7303846_3 Complex I intermediate-associated protein 30 (CIA30) - - - 0.00000000000000000000000000000000000000000000000000000008375 201.0
DTH2_k127_7303846_4 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000004156 196.0
DTH2_k127_7303846_5 CbiX K03794 - 4.99.1.4 0.000000000000000000000000000007313 123.0
DTH2_k127_7303846_6 Protein conserved in bacteria - - - 0.000000000000000000000000002006 117.0
DTH2_k127_7333173_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 2.002e-218 693.0
DTH2_k127_7333173_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.071e-195 619.0
DTH2_k127_7333173_2 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 350.0
DTH2_k127_7333173_3 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000313 272.0
DTH2_k127_7333173_4 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000007391 200.0
DTH2_k127_7340273_0 AcrB/AcrD/AcrF family - - - 0.0 1521.0
DTH2_k127_7340273_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.497e-295 915.0
DTH2_k127_7340273_10 TonB dependent receptor - - - 3.399e-212 692.0
DTH2_k127_7340273_11 Major facilitator Superfamily K08162,K08226,K16211 - - 5.173e-199 637.0
DTH2_k127_7340273_12 Binding-protein-dependent transport system inner membrane component K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 551.0
DTH2_k127_7340273_13 Belongs to the ABC transporter superfamily K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 546.0
DTH2_k127_7340273_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 521.0
DTH2_k127_7340273_15 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 530.0
DTH2_k127_7340273_16 Oligopeptide/dipeptide transporter, C-terminal region K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 523.0
DTH2_k127_7340273_17 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 516.0
DTH2_k127_7340273_18 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 514.0
DTH2_k127_7340273_19 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 514.0
DTH2_k127_7340273_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 2.63e-273 848.0
DTH2_k127_7340273_20 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 492.0
DTH2_k127_7340273_21 N-terminal TM domain of oligopeptide transport permease C K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 486.0
DTH2_k127_7340273_22 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 467.0
DTH2_k127_7340273_23 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 465.0
DTH2_k127_7340273_24 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 446.0
DTH2_k127_7340273_25 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 432.0
DTH2_k127_7340273_26 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 432.0
DTH2_k127_7340273_27 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 368.0
DTH2_k127_7340273_28 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 339.0
DTH2_k127_7340273_29 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 327.0
DTH2_k127_7340273_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.071e-268 837.0
DTH2_k127_7340273_30 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 330.0
DTH2_k127_7340273_31 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 312.0
DTH2_k127_7340273_32 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 325.0
DTH2_k127_7340273_33 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 315.0
DTH2_k127_7340273_34 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 304.0
DTH2_k127_7340273_35 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
DTH2_k127_7340273_36 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 301.0
DTH2_k127_7340273_37 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002004 279.0
DTH2_k127_7340273_38 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002599 274.0
DTH2_k127_7340273_39 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004436 267.0
DTH2_k127_7340273_4 Peptidase family M3 K01392 - 3.4.24.15 1.983e-263 829.0
DTH2_k127_7340273_40 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 250.0
DTH2_k127_7340273_41 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000104 257.0
DTH2_k127_7340273_42 LysE type translocator K06895 - - 0.00000000000000000000000000000000000000000000000000000000000002455 220.0
DTH2_k127_7340273_43 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000001133 209.0
DTH2_k127_7340273_44 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000001259 198.0
DTH2_k127_7340273_45 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000000000000000000002484 196.0
DTH2_k127_7340273_46 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000002817 191.0
DTH2_k127_7340273_47 - - - - 0.0000000000000000000000000003375 117.0
DTH2_k127_7340273_48 Cytochrome c - - - 0.0000000000000000000000000005474 118.0
DTH2_k127_7340273_49 - - - - 0.00000000000000000000002309 104.0
DTH2_k127_7340273_5 Acetyl xylan esterase (AXE1) - - - 2.272e-261 821.0
DTH2_k127_7340273_6 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 1.63e-255 804.0
DTH2_k127_7340273_7 Peptidase S46 - - - 1.784e-231 735.0
DTH2_k127_7340273_8 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 4.246e-221 702.0
DTH2_k127_7340273_9 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 7.596e-219 692.0
DTH2_k127_7378586_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 593.0
DTH2_k127_7378586_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 535.0
DTH2_k127_7378586_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000237 281.0
DTH2_k127_7378586_3 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000006661 236.0
DTH2_k127_7378586_4 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000004646 133.0
DTH2_k127_7378586_5 Zinc-finger domain - - - 0.0000000000000000006342 99.0
DTH2_k127_7410988_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.0 1070.0
DTH2_k127_7410988_1 PFAM carboxyl transferase K01615 - 4.1.1.70 6.993e-295 912.0
DTH2_k127_7410988_10 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 311.0
DTH2_k127_7410988_11 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009474 269.0
DTH2_k127_7410988_12 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.00000000000000002218 85.0
DTH2_k127_7410988_13 Cysteine-rich domain - - - 0.000005121 49.0
DTH2_k127_7410988_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 4.385e-244 763.0
DTH2_k127_7410988_3 acyl-CoA dehydrogenase K00252 - 1.3.8.6 2.652e-219 683.0
DTH2_k127_7410988_4 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 4.868e-211 659.0
DTH2_k127_7410988_5 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 588.0
DTH2_k127_7410988_6 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 570.0
DTH2_k127_7410988_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 530.0
DTH2_k127_7410988_8 TIGRFAM sodium ion-translocating decarboxylase, beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 532.0
DTH2_k127_7410988_9 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 419.0
DTH2_k127_7425625_0 aminopeptidase N K01256 - 3.4.11.2 7.837e-223 702.0
DTH2_k127_7425625_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 522.0
DTH2_k127_7425625_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 370.0
DTH2_k127_7425625_3 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 346.0
DTH2_k127_7513699_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0 1598.0
DTH2_k127_7513699_1 exporters of the RND superfamily K07003 - - 0.0 1198.0
DTH2_k127_7513699_10 Protein of unknown function (DUF1329) - - - 2.231e-209 658.0
DTH2_k127_7513699_11 Major Facilitator Superfamily - - - 8.361e-201 632.0
DTH2_k127_7513699_12 Protein of unknown function (DUF1302) - - - 1.89e-198 637.0
DTH2_k127_7513699_13 Saccharopine dehydrogenase NADP binding domain - - - 1.008e-195 616.0
DTH2_k127_7513699_14 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 603.0
DTH2_k127_7513699_15 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 584.0
DTH2_k127_7513699_16 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 560.0
DTH2_k127_7513699_17 Alcohol dehydrogenase groes K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 469.0
DTH2_k127_7513699_18 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 465.0
DTH2_k127_7513699_19 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 456.0
DTH2_k127_7513699_2 PFAM Sulfatase - - - 0.0 1179.0
DTH2_k127_7513699_20 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 396.0
DTH2_k127_7513699_21 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 379.0
DTH2_k127_7513699_22 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 370.0
DTH2_k127_7513699_23 NADPH dehydrogenase K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 362.0
DTH2_k127_7513699_24 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 372.0
DTH2_k127_7513699_25 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 356.0
DTH2_k127_7513699_26 IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 335.0
DTH2_k127_7513699_27 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 314.0
DTH2_k127_7513699_28 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 318.0
DTH2_k127_7513699_29 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 300.0
DTH2_k127_7513699_3 helix_turn_helix, Lux Regulon K03556 - - 0.0 1142.0
DTH2_k127_7513699_30 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 302.0
DTH2_k127_7513699_31 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 295.0
DTH2_k127_7513699_32 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 291.0
DTH2_k127_7513699_33 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 294.0
DTH2_k127_7513699_34 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001267 276.0
DTH2_k127_7513699_35 short-chain - - - 0.000000000000000000000000000000000000000000000000000000000000000001182 235.0
DTH2_k127_7513699_36 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000002715 238.0
DTH2_k127_7513699_37 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000003867 215.0
DTH2_k127_7513699_38 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000003687 222.0
DTH2_k127_7513699_39 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000205 208.0
DTH2_k127_7513699_4 Cytochrome c554 and c-prime - - - 3.164e-309 964.0
DTH2_k127_7513699_40 - - - - 0.00000000000000000000000000000000000000000000000000000000121 205.0
DTH2_k127_7513699_41 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.00000000000000000000000000000000000000000000000000000002889 209.0
DTH2_k127_7513699_42 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000005172 209.0
DTH2_k127_7513699_44 - - - - 0.00000000000000000000000000000000000000000000000000328 196.0
DTH2_k127_7513699_45 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000000000000000001165 123.0
DTH2_k127_7513699_46 Transcriptional regulator K07726 - - 0.000000000000000000000000001369 111.0
DTH2_k127_7513699_47 iron-sulfur cluster assembly K07400,K13628 - - 0.000000000000000000000003579 104.0
DTH2_k127_7513699_49 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 0.000000000000007556 78.0
DTH2_k127_7513699_5 AMP-binding enzyme C-terminal domain K02182,K20034 GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044464,GO:0071704 6.2.1.44,6.2.1.48 3.751e-291 901.0
DTH2_k127_7513699_50 Transcriptional regulator K07726 - - 0.000000000001315 69.0
DTH2_k127_7513699_51 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000003559 55.0
DTH2_k127_7513699_52 long-chain fatty acid transport protein K06076 - - 0.00006006 55.0
DTH2_k127_7513699_6 AMP-binding enzyme C-terminal domain K00666 - - 1.49e-270 839.0
DTH2_k127_7513699_7 Protein of unknown function (DUF1302) - - - 8.957e-256 803.0
DTH2_k127_7513699_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.637e-231 719.0
DTH2_k127_7513699_9 Carboxypeptidase regulatory-like domain - - - 8.584e-213 679.0
DTH2_k127_7524903_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.375e-276 858.0
DTH2_k127_7524903_1 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 505.0
DTH2_k127_7524903_10 dioxygenase of extradiol dioxygenase family K06991 - - 0.000000000000000000000000000000000000000000004189 175.0
DTH2_k127_7524903_11 polyhydroxyalkanoic acid system protein - - - 0.0000000000000000000015 98.0
DTH2_k127_7524903_2 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 437.0
DTH2_k127_7524903_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 413.0
DTH2_k127_7524903_4 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 388.0
DTH2_k127_7524903_5 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 303.0
DTH2_k127_7524903_6 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 297.0
DTH2_k127_7524903_7 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000036 278.0
DTH2_k127_7524903_8 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001069 211.0
DTH2_k127_7524903_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000001425 169.0
DTH2_k127_757899_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.295e-238 762.0
DTH2_k127_757899_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 552.0
DTH2_k127_757899_10 YqjK-like protein - - - 0.000000000317 64.0
DTH2_k127_757899_2 Ubiquinone biosynthesis hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 477.0
DTH2_k127_757899_3 exodeoxyribonuclease iii K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 426.0
DTH2_k127_757899_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 305.0
DTH2_k127_757899_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005187 260.0
DTH2_k127_757899_6 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000001402 181.0
DTH2_k127_757899_7 - - - - 0.00000000000000000000000000000000003459 145.0
DTH2_k127_757899_8 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000001048 127.0
DTH2_k127_757899_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000001164 89.0
DTH2_k127_7590128_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 419.0
DTH2_k127_7590128_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 387.0
DTH2_k127_7590128_2 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000176 241.0
DTH2_k127_7590128_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0000000000000000000000000000000000000000000000000000000000003253 213.0
DTH2_k127_7590128_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000005273 187.0
DTH2_k127_7590128_5 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.00000000000000000000000000000000000003243 155.0
DTH2_k127_7590128_6 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000001021 123.0
DTH2_k127_7590128_7 Rv0623-like transcription factor K19687 - - 0.00000000000000000000000000001148 119.0
DTH2_k127_7598700_0 nucleoside-diphosphate sugar epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 607.0
DTH2_k127_7598700_1 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 592.0
DTH2_k127_7598700_11 Uncharacterized protein conserved in bacteria (DUF2256) - - - 0.0000000000000006051 79.0
DTH2_k127_7598700_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000002462 67.0
DTH2_k127_7598700_13 BEST Arabidopsis thaliana protein match is Polyketide cyclase dehydrase and lipid transport protein (TAIR AT4G01650.1) - - - 0.0000009088 59.0
DTH2_k127_7598700_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 466.0
DTH2_k127_7598700_3 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 401.0
DTH2_k127_7598700_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 354.0
DTH2_k127_7598700_5 BAAT Acyl-CoA thioester hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 335.0
DTH2_k127_7598700_6 Complex I intermediate-associated protein 30 - - - 0.0000000000000000000000000000000000000000000000000000003393 197.0
DTH2_k127_7598700_7 Thiamine-binding protein - - - 0.0000000000000000000000000000000000000000000001302 169.0
DTH2_k127_7598700_8 hemerythrin-like metal-binding K07216 - - 0.00000000000000000000000006106 112.0
DTH2_k127_7598700_9 - - - - 0.00000000000000000000016 99.0
DTH2_k127_7626926_0 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 459.0
DTH2_k127_7626926_1 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 439.0
DTH2_k127_7626926_2 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 359.0
DTH2_k127_7626926_3 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000001172 175.0
DTH2_k127_7626926_4 Cbb3-type cytochrome oxidase component FixQ - - - 0.000000000000000000000002477 106.0
DTH2_k127_7631363_0 AcrB/AcrD/AcrF family - - - 0.0 1337.0
DTH2_k127_7631363_1 COG1538 Outer membrane protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 458.0
DTH2_k127_7631363_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 444.0
DTH2_k127_7631363_3 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 441.0
DTH2_k127_7631363_4 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003167 297.0
DTH2_k127_7631363_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000007859 243.0
DTH2_k127_7631363_6 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000001098 154.0
DTH2_k127_7631363_7 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000001142 145.0
DTH2_k127_7664142_0 TRAP dicarboxylate transporter, DctM subunit K03299 - - 5.414e-255 807.0
DTH2_k127_7664142_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.42e-232 725.0
DTH2_k127_7664142_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
DTH2_k127_7664142_11 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
DTH2_k127_7664142_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000006663 223.0
DTH2_k127_7664142_13 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000007102 215.0
DTH2_k127_7664142_14 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000000000000005481 192.0
DTH2_k127_7664142_15 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000004541 120.0
DTH2_k127_7664142_2 modulator of DNA gyrase K03592 - - 1.339e-201 637.0
DTH2_k127_7664142_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 572.0
DTH2_k127_7664142_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 569.0
DTH2_k127_7664142_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 562.0
DTH2_k127_7664142_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 536.0
DTH2_k127_7664142_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 514.0
DTH2_k127_7664142_8 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005765 257.0
DTH2_k127_7664142_9 COG2186 Transcriptional regulators K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004444 254.0
DTH2_k127_7664271_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 4.578e-233 729.0
DTH2_k127_7664271_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 1.649e-208 662.0
DTH2_k127_7664271_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 394.0
DTH2_k127_7664271_3 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 349.0
DTH2_k127_7664271_4 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000001179 250.0
DTH2_k127_7664271_5 FHA domain - - - 0.00000000000000000000000000000000000000000000000000001642 204.0
DTH2_k127_7664271_6 Protein of unknown function (DUF2846) - - - 0.00000000000000000000000000000000000000000006402 164.0
DTH2_k127_7664271_7 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000001054 163.0
DTH2_k127_7669788_0 Fis family transcriptional regulator - - - 1.371e-277 863.0
DTH2_k127_7669788_1 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.000000000000000000000000000000000000000000000000000000003117 203.0
DTH2_k127_7669788_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000002114 79.0
DTH2_k127_7669788_3 tryptophan synthase activity K01696,K06001 - 4.2.1.20 0.0001812 44.0
DTH2_k127_7681924_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1513.0
DTH2_k127_7681924_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 2.94e-224 699.0
DTH2_k127_7681924_2 NADH dehydrogenase K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 611.0
DTH2_k127_7681924_3 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 594.0
DTH2_k127_7681924_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007342 276.0
DTH2_k127_7681924_5 4 iron, 4 sulfur cluster binding K03522,K13795,K15511,K19516 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 259.0
DTH2_k127_7681924_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000001747 192.0
DTH2_k127_7715036_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 515.0
DTH2_k127_7715036_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 517.0
DTH2_k127_7715036_2 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 491.0
DTH2_k127_7715036_3 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000459 153.0
DTH2_k127_7715036_4 Pfam:DUF59 - - - 0.0000000000000000000000000000000001136 135.0
DTH2_k127_7715036_5 Vitamin k epoxide reductase - - - 0.0000000000000000000000000341 109.0
DTH2_k127_7715036_6 Phosphopantetheine attachment site - - - 0.0000000000000000000000002747 119.0
DTH2_k127_7724159_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1465.0
DTH2_k127_7724159_1 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1363.0
DTH2_k127_7724159_10 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 482.0
DTH2_k127_7724159_11 fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 422.0
DTH2_k127_7724159_12 transcriptional K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 370.0
DTH2_k127_7724159_13 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 323.0
DTH2_k127_7724159_14 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.00000000000000000000000000000000000000000000000000000000000376 215.0
DTH2_k127_7724159_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000009305 219.0
DTH2_k127_7724159_16 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000001931 186.0
DTH2_k127_7724159_17 Succinate dehydrogenase, hydrophobic K00242 - - 0.0000000000000000000000000000000000000003772 155.0
DTH2_k127_7724159_18 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000002032 152.0
DTH2_k127_7724159_19 PIN domain - - - 0.00000000000000000000003623 106.0
DTH2_k127_7724159_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1063.0
DTH2_k127_7724159_20 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000003558 78.0
DTH2_k127_7724159_21 toxin-antitoxin pair type II binding - - - 0.0000000000001018 74.0
DTH2_k127_7724159_22 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000129 59.0
DTH2_k127_7724159_23 - - - - 0.000009325 55.0
DTH2_k127_7724159_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.706e-261 807.0
DTH2_k127_7724159_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 4.527e-223 700.0
DTH2_k127_7724159_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - - 1.686e-199 629.0
DTH2_k127_7724159_6 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 580.0
DTH2_k127_7724159_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 529.0
DTH2_k127_7724159_8 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 542.0
DTH2_k127_7724159_9 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 497.0
DTH2_k127_7724228_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1215.0
DTH2_k127_7724228_1 peptidase, U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 627.0
DTH2_k127_7724228_2 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 438.0
DTH2_k127_7724228_3 Glutathione S-transferase, N-terminal domain protein K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000005186 245.0
DTH2_k127_7724228_4 Glycine cleavage system regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000002069 217.0
DTH2_k127_7724228_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000001834 170.0
DTH2_k127_7724228_6 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000001689 113.0
DTH2_k127_7724228_7 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid K19164 - - 0.000000000000000000000003076 106.0
DTH2_k127_7724228_8 Plasmid maintenance protein CcdB K19163 - - 0.0000000000000002944 86.0
DTH2_k127_7743138_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 1.643e-281 880.0
DTH2_k127_7743138_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 499.0
DTH2_k127_7743138_10 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000001177 244.0
DTH2_k127_7743138_11 sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000000000001073 155.0
DTH2_k127_7743138_12 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000006221 139.0
DTH2_k127_7743138_13 - - - - 0.00000000000000003411 87.0
DTH2_k127_7743138_2 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 422.0
DTH2_k127_7743138_3 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 377.0
DTH2_k127_7743138_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 383.0
DTH2_k127_7743138_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 345.0
DTH2_k127_7743138_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 317.0
DTH2_k127_7743138_7 Putative heavy-metal chelation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 303.0
DTH2_k127_7743138_8 PBP superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001504 243.0
DTH2_k127_7743138_9 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000002603 229.0
DTH2_k127_7763062_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.404e-261 815.0
DTH2_k127_7763062_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 2.152e-261 857.0
DTH2_k127_7763062_2 Major facilitator Superfamily K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 477.0
DTH2_k127_7763062_3 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 371.0
DTH2_k127_7763062_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 293.0
DTH2_k127_7763062_5 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001612 277.0
DTH2_k127_7763062_6 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006025 273.0
DTH2_k127_7763062_7 yiaA/B two helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004567 224.0
DTH2_k127_7763062_8 - - - - 0.00000000000000000000000000000005927 130.0
DTH2_k127_7771548_0 peptidase, U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 532.0
DTH2_k127_7771548_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 533.0
DTH2_k127_7771548_2 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 426.0
DTH2_k127_7771548_3 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
DTH2_k127_7771548_4 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000009885 208.0
DTH2_k127_7771548_5 Sterol-binding domain protein - - - 0.00000000000000000000000000000000000000000000000002904 184.0
DTH2_k127_7771548_6 Rubredoxin - - - 0.00000000000000000000005913 104.0
DTH2_k127_7771548_7 PIN domain - - - 0.000000000622 63.0
DTH2_k127_7771548_8 - - - - 0.0000001432 56.0
DTH2_k127_7771548_9 PIN domain K07063 - - 0.00006763 47.0
DTH2_k127_7819247_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 3.463e-321 996.0
DTH2_k127_7819247_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 2.116e-247 776.0
DTH2_k127_7819247_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000001688 201.0
DTH2_k127_7819247_11 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000001432 192.0
DTH2_k127_7819247_12 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000003176 156.0
DTH2_k127_7819247_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000004283 156.0
DTH2_k127_7819247_14 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000002204 128.0
DTH2_k127_7819247_15 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000000000000001782 106.0
DTH2_k127_7819247_16 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000003557 79.0
DTH2_k127_7819247_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.633e-215 677.0
DTH2_k127_7819247_3 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 419.0
DTH2_k127_7819247_4 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 366.0
DTH2_k127_7819247_5 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 325.0
DTH2_k127_7819247_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000000000008048 231.0
DTH2_k127_7819247_9 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000006522 211.0
DTH2_k127_792715_0 Protein of unknown function (DUF229) - - - 3.746e-223 708.0
DTH2_k127_792715_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.787e-197 633.0
DTH2_k127_792715_3 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 387.0
DTH2_k127_792715_4 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 327.0
DTH2_k127_792715_5 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000648 291.0
DTH2_k127_795429_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1416.0
DTH2_k127_795429_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1015.0
DTH2_k127_795429_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 480.0
DTH2_k127_795429_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 416.0
DTH2_k127_795429_12 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 414.0
DTH2_k127_795429_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 403.0
DTH2_k127_795429_14 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 404.0
DTH2_k127_795429_15 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 406.0
DTH2_k127_795429_16 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 394.0
DTH2_k127_795429_17 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 383.0
DTH2_k127_795429_18 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 293.0
DTH2_k127_795429_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002108 288.0
DTH2_k127_795429_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 1.069e-267 847.0
DTH2_k127_795429_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008564 283.0
DTH2_k127_795429_21 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000399 256.0
DTH2_k127_795429_22 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002507 254.0
DTH2_k127_795429_23 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000008504 249.0
DTH2_k127_795429_24 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000002184 233.0
DTH2_k127_795429_25 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000006985 220.0
DTH2_k127_795429_26 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000003376 198.0
DTH2_k127_795429_27 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000001415 199.0
DTH2_k127_795429_28 NfeD-like C-terminal, partner-binding K07340 - - 0.0000000000000000000000000000000000000000001212 166.0
DTH2_k127_795429_29 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000001285 154.0
DTH2_k127_795429_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.781e-228 714.0
DTH2_k127_795429_30 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000009867 149.0
DTH2_k127_795429_31 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000000008047 153.0
DTH2_k127_795429_32 cation diffusion facilitator family transporter K14696 - - 0.0000000773 63.0
DTH2_k127_795429_4 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 2.371e-217 685.0
DTH2_k127_795429_5 Major Facilitator - - - 8.523e-212 663.0
DTH2_k127_795429_6 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 534.0
DTH2_k127_795429_7 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 526.0
DTH2_k127_795429_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 513.0
DTH2_k127_795429_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 485.0
DTH2_k127_7961388_0 ABC transporter transmembrane region K12536 - - 9.814e-271 844.0
DTH2_k127_7961388_1 TIGRFAM Type I secretion membrane fusion protein, HlyD K02022,K12537,K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 497.0
DTH2_k127_7961388_2 TIGRFAM type I secretion outer membrane protein, TolC K12538 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 445.0
DTH2_k127_7961388_3 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000000000000000000000000000437 127.0
DTH2_k127_7961388_4 Membrane fusogenic activity K09806 - - 0.000000000001039 68.0
DTH2_k127_7961388_5 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000002387 62.0
DTH2_k127_8065749_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.062e-205 654.0
DTH2_k127_8065749_1 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 447.0
DTH2_k127_8065749_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 423.0
DTH2_k127_8065749_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 347.0
DTH2_k127_8065749_4 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 344.0
DTH2_k127_8065749_5 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000198 209.0
DTH2_k127_8098592_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.898e-230 718.0
DTH2_k127_8098592_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 507.0
DTH2_k127_8098592_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 316.0
DTH2_k127_8098592_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 289.0
DTH2_k127_8098592_4 NADH dehydrogenase I subunit E K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001362 263.0
DTH2_k127_8098592_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000004603 215.0
DTH2_k127_8098592_6 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000000000000006088 142.0
DTH2_k127_8103426_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1117.0
DTH2_k127_8103426_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 1.889e-320 992.0
DTH2_k127_8103426_2 Aminotransferase K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 636.0
DTH2_k127_8103426_3 demethylmenaquinone methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 296.0
DTH2_k127_8103426_4 peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000008128 208.0
DTH2_k127_8103426_6 - - - - 0.00000000000002406 76.0
DTH2_k127_8149984_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 8.407e-232 726.0
DTH2_k127_8149984_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 561.0
DTH2_k127_8149984_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 512.0
DTH2_k127_8149984_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 472.0
DTH2_k127_8149984_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 435.0
DTH2_k127_8149984_5 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 325.0
DTH2_k127_8149984_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009512 252.0
DTH2_k127_8149984_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000002038 90.0
DTH2_k127_8160959_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06020 - 3.6.3.25 2.164e-300 926.0
DTH2_k127_8160959_1 Peptidase U32 K08303 - - 2.249e-253 796.0
DTH2_k127_8160959_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 392.0
DTH2_k127_8160959_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000004893 214.0
DTH2_k127_8160959_4 - - - - 0.000000000000000000000000000000000000000000000001707 181.0
DTH2_k127_8160959_5 - - - - 0.00000000000000000000004061 108.0
DTH2_k127_8160959_6 - - - - 0.0000000000003049 79.0
DTH2_k127_8177992_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1300.0
DTH2_k127_8177992_1 Anion transporter K03319 - - 1.82e-263 817.0
DTH2_k127_8177992_10 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 449.0
DTH2_k127_8177992_11 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 378.0
DTH2_k127_8177992_12 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 366.0
DTH2_k127_8177992_13 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 314.0
DTH2_k127_8177992_14 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 297.0
DTH2_k127_8177992_15 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009517 254.0
DTH2_k127_8177992_16 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000002521 220.0
DTH2_k127_8177992_17 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000001608 181.0
DTH2_k127_8177992_18 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000005554 122.0
DTH2_k127_8177992_19 Protein of unknown function (DUF2788) - - - 0.0000000000000000000000000005392 113.0
DTH2_k127_8177992_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.902e-247 766.0
DTH2_k127_8177992_20 S4 domain K14761 - - 0.00000000000000002447 83.0
DTH2_k127_8177992_22 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.000000000146 62.0
DTH2_k127_8177992_3 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.455e-225 705.0
DTH2_k127_8177992_4 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 582.0
DTH2_k127_8177992_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 575.0
DTH2_k127_8177992_6 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 562.0
DTH2_k127_8177992_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 549.0
DTH2_k127_8177992_8 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 533.0
DTH2_k127_8177992_9 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 478.0
DTH2_k127_8225561_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.25e-197 626.0
DTH2_k127_8225561_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 587.0
DTH2_k127_8225561_10 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000001234 134.0
DTH2_k127_8225561_11 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000004042 130.0
DTH2_k127_8225561_12 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000004939 96.0
DTH2_k127_8225561_2 Lysine transporter LysE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 321.0
DTH2_k127_8225561_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 304.0
DTH2_k127_8225561_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 293.0
DTH2_k127_8225561_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000266 252.0
DTH2_k127_8225561_6 Ecotin K08276 - - 0.0000000000000000000000000000000000000000000000000000000000000000004646 235.0
DTH2_k127_8225561_7 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000001464 183.0
DTH2_k127_8225561_8 addiction module killer protein - - - 0.00000000000000000000000000000000000000002465 154.0
DTH2_k127_8225561_9 Addiction module toxin, RelE StbE family K07334 - - 0.0000000000000000000000000000000000001098 143.0
DTH2_k127_8243695_0 CHAT domain - - - 6.957e-205 661.0
DTH2_k127_8243695_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 436.0
DTH2_k127_8243695_2 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 413.0
DTH2_k127_8243695_3 PFAM Patatin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 371.0
DTH2_k127_8243695_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001788 260.0
DTH2_k127_8243695_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000003527 179.0
DTH2_k127_8243695_6 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000000000001606 173.0
DTH2_k127_8243695_7 Belongs to the UPF0225 family K09858 - - 0.000000006584 59.0
DTH2_k127_8243695_8 Protein of unknown function (DUF2934) - - - 0.0000001886 55.0
DTH2_k127_8255198_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1009.0
DTH2_k127_8255198_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 424.0
DTH2_k127_8255198_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 373.0
DTH2_k127_8255198_3 protein containing LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 301.0
DTH2_k127_8255198_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000006632 250.0
DTH2_k127_8255198_5 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000002392 154.0
DTH2_k127_8385329_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 2.541e-307 951.0
DTH2_k127_8385329_1 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.000000000000000000000000000000000000000000000000000000004057 200.0
DTH2_k127_8385329_2 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000008305 189.0
DTH2_k127_8385329_3 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000000006092 189.0
DTH2_k127_8385329_4 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000007915 187.0
DTH2_k127_8385329_5 Fe-S assembly protein IscX - - - 0.00000000000000000000000153 104.0
DTH2_k127_8385329_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000029 69.0
DTH2_k127_8452464_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1259.0
DTH2_k127_8452464_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 526.0
DTH2_k127_8452464_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 470.0
DTH2_k127_8452464_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 396.0
DTH2_k127_8452464_4 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 350.0
DTH2_k127_8452464_5 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
DTH2_k127_8452464_6 Protein of unknown function (DUF721) - - - 0.0000000000000001937 85.0
DTH2_k127_8524788_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1227.0
DTH2_k127_8524788_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 3.946e-245 763.0
DTH2_k127_8524788_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 378.0
DTH2_k127_8732446_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 459.0
DTH2_k127_8732446_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 445.0
DTH2_k127_8732446_10 Domain of unknown function (DUF1850) - - - 0.000000000000000000000000000000000000000000002455 169.0
DTH2_k127_8732446_11 Nucleotidyltransferase substrate binding protein like - - - 0.000000000000000000000000000000000000000000003428 168.0
DTH2_k127_8732446_12 PEP-CTERM motif - - - 0.000000000000000000000000000000000000009179 154.0
DTH2_k127_8732446_13 RNA uridylyltransferase activity - - - 0.0000000000000000000000000002969 117.0
DTH2_k127_8732446_14 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000002276 65.0
DTH2_k127_8732446_15 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000001296 59.0
DTH2_k127_8732446_2 recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 381.0
DTH2_k127_8732446_3 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 284.0
DTH2_k127_8732446_4 TRAP transporter 4TM 12TM fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003022 241.0
DTH2_k127_8732446_5 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000009625 210.0
DTH2_k127_8732446_6 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000009981 205.0
DTH2_k127_8732446_7 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000001607 202.0
DTH2_k127_8732446_8 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000006863 190.0
DTH2_k127_8732446_9 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000001999 180.0
DTH2_k127_8876386_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.527e-317 987.0
DTH2_k127_8876386_1 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 374.0
DTH2_k127_8876386_10 Pfam cytochrome c K08738 - - 0.000000000000000001476 87.0
DTH2_k127_8876386_12 Nucleotidyltransferase - - - 0.00000000001345 69.0
DTH2_k127_8876386_13 response regulator - - - 0.000000000804 61.0
DTH2_k127_8876386_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 292.0
DTH2_k127_8876386_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000005863 261.0
DTH2_k127_8876386_4 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000005895 207.0
DTH2_k127_8876386_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07662 - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
DTH2_k127_8876386_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000005392 113.0
DTH2_k127_8876386_7 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000000000000000002206 106.0
DTH2_k127_8876386_8 Domain of unknown function (DUF1924) - - - 0.000000000000000000002191 100.0
DTH2_k127_8883137_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 9.599e-284 900.0
DTH2_k127_8883137_1 Ammonium Transporter K03320 - - 3.227e-230 721.0
DTH2_k127_8883137_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 403.0
DTH2_k127_8883137_3 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 358.0
DTH2_k127_8883137_4 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000004148 209.0
DTH2_k127_8883137_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000008993 204.0
DTH2_k127_8883137_6 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000456 177.0
DTH2_k127_8883137_7 transcriptional - - - 0.0000000000000000000000000000000000000000008787 160.0
DTH2_k127_8883137_8 PIN domain - - - 0.000000000000000000000000003084 125.0
DTH2_k127_8883137_9 Sel1-like repeats. K07126 - - 0.00000000000000009274 93.0
DTH2_k127_8894650_0 Hemolysin-type calcium-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 336.0
DTH2_k127_8894650_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000003897 222.0
DTH2_k127_8894650_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000001173 184.0
DTH2_k127_8894650_3 PFAM SpoVT AbrB - - - 0.000000000000000000000000000000001326 131.0
DTH2_k127_8894650_4 HlyD membrane-fusion protein of T1SS K02022,K11003 - - 0.0000000000000005903 78.0
DTH2_k127_8894650_5 Lipase (class 3) - - - 0.000000000000082 85.0
DTH2_k127_88999_0 Domain of unknown function (DUF2172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 533.0
DTH2_k127_88999_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 505.0
DTH2_k127_88999_10 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000001163 193.0
DTH2_k127_88999_11 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000008166 182.0
DTH2_k127_88999_12 DegT DnrJ EryC1 - - - 0.00000000000000000006662 98.0
DTH2_k127_88999_2 PFAM Iron-containing alcohol dehydrogenase K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 484.0
DTH2_k127_88999_3 TIGRFAM radical SAM additional 4Fe4S-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 423.0
DTH2_k127_88999_4 PFAM N-acetylneuraminic acid synthase domain K01654,K18430 - 2.5.1.101,2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 396.0
DTH2_k127_88999_5 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 373.0
DTH2_k127_88999_6 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 358.0
DTH2_k127_88999_7 DegT/DnrJ/EryC1/StrS aminotransferase family K19715 - 2.6.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 364.0
DTH2_k127_88999_8 transferase activity, transferring amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 325.0
DTH2_k127_88999_9 TIGRFAM 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000001738 197.0
DTH2_k127_8903040_0 Peptidase M1 membrane alanine aminopeptidase - - - 0.0 1089.0
DTH2_k127_8903040_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.138e-247 772.0
DTH2_k127_8903040_10 - - - - 0.000000000000000000000000000000000000002474 151.0
DTH2_k127_8903040_11 Protein of unknown function (DUF3301) - - - 0.0000000000000000000000002173 108.0
DTH2_k127_8903040_12 Protein conserved in bacteria - - - 0.000000000000003135 78.0
DTH2_k127_8903040_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 7.847e-203 637.0
DTH2_k127_8903040_3 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 426.0
DTH2_k127_8903040_4 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 362.0
DTH2_k127_8903040_5 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 347.0
DTH2_k127_8903040_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 304.0
DTH2_k127_8903040_7 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.00000000000000000000000000000000000000000000000000000000000000000001359 235.0
DTH2_k127_8903040_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000003072 188.0
DTH2_k127_8903040_9 Beta-Ig-H3 fasciclin - - - 0.00000000000000000000000000000000000000000000002764 173.0
DTH2_k127_8911882_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 569.0
DTH2_k127_8911882_1 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 524.0
DTH2_k127_8911882_10 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
DTH2_k127_8911882_11 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 299.0
DTH2_k127_8911882_12 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001427 273.0
DTH2_k127_8911882_13 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002522 263.0
DTH2_k127_8911882_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003517 238.0
DTH2_k127_8911882_15 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000008968 206.0
DTH2_k127_8911882_16 YCII-related domain K09780 - - 0.00000000000000000000000000000000000000005535 153.0
DTH2_k127_8911882_17 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000004312 115.0
DTH2_k127_8911882_18 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000002271 109.0
DTH2_k127_8911882_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 513.0
DTH2_k127_8911882_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 505.0
DTH2_k127_8911882_4 Protein of unknown function (DUF2863) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 448.0
DTH2_k127_8911882_5 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 434.0
DTH2_k127_8911882_6 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 395.0
DTH2_k127_8911882_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 371.0
DTH2_k127_8911882_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 329.0
DTH2_k127_8911882_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
DTH2_k127_8929627_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.596e-197 621.0
DTH2_k127_8929627_1 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 604.0
DTH2_k127_8929627_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 485.0
DTH2_k127_8929627_3 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 447.0
DTH2_k127_8929627_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000001677 207.0
DTH2_k127_8929627_5 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000137 137.0
DTH2_k127_8929627_6 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000002517 99.0
DTH2_k127_8934635_0 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 428.0
DTH2_k127_8934635_1 cytochrome c-type protein K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 314.0
DTH2_k127_8934635_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001367 285.0
DTH2_k127_8934635_3 cytochrome d1 heme K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005317 244.0
DTH2_k127_8934635_4 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000000000000000000000008242 153.0
DTH2_k127_8934635_5 blue (type 1) copper - - - 0.0000000000000000000000000000000000000639 145.0
DTH2_k127_8934635_6 Cytochrome c K08738 - - 0.000000000000000000000000000000164 126.0
DTH2_k127_8934635_7 Histidine kinase - - - 0.00000000000000001388 87.0
DTH2_k127_8936159_0 Carbamoyltransferase C-terminus K00612 - - 0.0 1085.0
DTH2_k127_8936159_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 3.642e-298 923.0
DTH2_k127_8936159_10 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 319.0
DTH2_k127_8936159_11 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 325.0
DTH2_k127_8936159_12 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004379 278.0
DTH2_k127_8936159_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004925 267.0
DTH2_k127_8936159_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002539 251.0
DTH2_k127_8936159_15 Toluene tolerance protein - - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
DTH2_k127_8936159_16 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000000000000000000000000000000000000000000005119 213.0
DTH2_k127_8936159_17 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000002885 208.0
DTH2_k127_8936159_18 Methyltransferase domain - - - 0.00000000000000000000000000000000002914 143.0
DTH2_k127_8936159_19 methyltransferase - - - 0.0000000000000000000000000000004695 139.0
DTH2_k127_8936159_2 Glycosyl transferases group 1 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 595.0
DTH2_k127_8936159_20 Radical SAM superfamily - - - 0.0000489 46.0
DTH2_k127_8936159_3 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 578.0
DTH2_k127_8936159_4 Two-component sensor kinase N-terminal K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 525.0
DTH2_k127_8936159_5 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 452.0
DTH2_k127_8936159_6 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 403.0
DTH2_k127_8936159_7 Protein of unknown function (DUF229) K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 398.0
DTH2_k127_8936159_8 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 359.0
DTH2_k127_8936159_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 331.0
DTH2_k127_895702_0 Wax ester synthase-like Acyl-CoA acyltransferase domain - GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009268,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010035,GO:0010447,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0043207,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0075136,GO:0097366,GO:1901576,GO:1901698,GO:1901700 - 4.597e-208 656.0
DTH2_k127_895702_1 Wax ester synthase-like Acyl-CoA acyltransferase domain - GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009268,GO:0009628,GO:0009987,GO:0010035,GO:0010447,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 590.0
DTH2_k127_895702_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 576.0
DTH2_k127_895702_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004171 257.0
DTH2_k127_895702_4 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002826 250.0
DTH2_k127_8961858_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1406.0
DTH2_k127_8961858_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.006e-314 968.0
DTH2_k127_8961858_10 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 570.0
DTH2_k127_8961858_11 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 569.0
DTH2_k127_8961858_12 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 541.0
DTH2_k127_8961858_13 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 507.0
DTH2_k127_8961858_14 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 490.0
DTH2_k127_8961858_15 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 451.0
DTH2_k127_8961858_16 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 439.0
DTH2_k127_8961858_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 435.0
DTH2_k127_8961858_18 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 433.0
DTH2_k127_8961858_19 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 428.0
DTH2_k127_8961858_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.414e-311 963.0
DTH2_k127_8961858_20 drug resistance K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 396.0
DTH2_k127_8961858_21 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 372.0
DTH2_k127_8961858_22 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 360.0
DTH2_k127_8961858_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 328.0
DTH2_k127_8961858_24 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 306.0
DTH2_k127_8961858_25 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000428 276.0
DTH2_k127_8961858_26 HAD-hyrolase-like K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 254.0
DTH2_k127_8961858_27 SmpB protein K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009699 251.0
DTH2_k127_8961858_28 Oligoketide cyclase lipid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002435 237.0
DTH2_k127_8961858_29 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
DTH2_k127_8961858_3 RQC K03654 - 3.6.4.12 1.136e-286 890.0
DTH2_k127_8961858_30 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001611 192.0
DTH2_k127_8961858_31 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000000349 176.0
DTH2_k127_8961858_32 AbiEi antitoxin C-terminal domain - - - 0.0000000000000000000000000000000000000000000006401 168.0
DTH2_k127_8961858_33 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000000000000001098 154.0
DTH2_k127_8961858_34 Protein of unknown function (DUF465) - - - 0.00000000000000004335 82.0
DTH2_k127_8961858_35 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000001358 59.0
DTH2_k127_8961858_36 - - - - 0.000004035 51.0
DTH2_k127_8961858_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.341e-276 865.0
DTH2_k127_8961858_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.889e-250 779.0
DTH2_k127_8961858_6 2-nitropropane dioxygenase K00459 - 1.13.12.16 1.404e-236 736.0
DTH2_k127_8961858_7 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.938e-199 625.0
DTH2_k127_8961858_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 576.0
DTH2_k127_8961858_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 579.0
DTH2_k127_89620_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004786 261.0
DTH2_k127_89620_1 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000002374 218.0
DTH2_k127_89620_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000001831 196.0
DTH2_k127_89620_3 - - - - 0.0000000000000000000000000003467 115.0
DTH2_k127_89620_4 Cytochrome c - - - 0.0000000000000000000000000007137 117.0
DTH2_k127_8982478_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1904.0
DTH2_k127_8982478_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1141.0
DTH2_k127_8982478_10 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 539.0
DTH2_k127_8982478_11 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 469.0
DTH2_k127_8982478_12 Pyruvate kinase, alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 448.0
DTH2_k127_8982478_13 PFAM 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 407.0
DTH2_k127_8982478_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 439.0
DTH2_k127_8982478_15 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 392.0
DTH2_k127_8982478_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 390.0
DTH2_k127_8982478_17 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 361.0
DTH2_k127_8982478_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 388.0
DTH2_k127_8982478_19 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 321.0
DTH2_k127_8982478_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.373e-300 936.0
DTH2_k127_8982478_20 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001324 258.0
DTH2_k127_8982478_21 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000003487 209.0
DTH2_k127_8982478_22 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000007778 204.0
DTH2_k127_8982478_23 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000008242 199.0
DTH2_k127_8982478_24 membrane - - - 0.000000000000000000000000000000000000000000000000000003137 196.0
DTH2_k127_8982478_25 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000002562 191.0
DTH2_k127_8982478_26 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000001681 115.0
DTH2_k127_8982478_28 - - - - 0.0000000003963 63.0
DTH2_k127_8982478_29 - - - - 0.0000001901 57.0
DTH2_k127_8982478_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.626e-283 885.0
DTH2_k127_8982478_4 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.27e-278 861.0
DTH2_k127_8982478_5 Circularly permuted ATP-grasp type 2 - - - 1.518e-258 803.0
DTH2_k127_8982478_6 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 2.618e-245 775.0
DTH2_k127_8982478_7 Glycosyl hydrolase family 57 - - - 1.197e-209 669.0
DTH2_k127_8982478_8 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.289e-207 652.0
DTH2_k127_8982478_9 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 2.035e-203 639.0
DTH2_k127_909502_0 Ferrous iron transport protein B K04759 - - 1.67e-230 732.0
DTH2_k127_909502_1 DNA polymerase III K02342 - 2.7.7.7 4.139e-205 650.0
DTH2_k127_909502_2 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 506.0
DTH2_k127_909502_3 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 454.0
DTH2_k127_909502_4 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 291.0
DTH2_k127_909502_5 PFAM MaoC domain protein dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000001735 243.0
DTH2_k127_909502_6 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000007344 247.0
DTH2_k127_909502_7 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.00000000000000000000000000000000000000000000002412 173.0
DTH2_k127_909502_8 Sterol carrier protein - - - 0.0005638 48.0
DTH2_k127_9155658_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 2.287e-291 902.0
DTH2_k127_9155658_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 595.0
DTH2_k127_9155658_10 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000002465 146.0
DTH2_k127_9155658_11 - - - - 0.0000000000000000000000000000000993 134.0
DTH2_k127_9155658_12 - - - - 0.0000000000000000001766 98.0
DTH2_k127_9155658_13 Prokaryotic N-terminal methylation motif - - - 0.000000000000002267 82.0
DTH2_k127_9155658_2 Bacterial regulatory protein, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 541.0
DTH2_k127_9155658_3 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 510.0
DTH2_k127_9155658_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 439.0
DTH2_k127_9155658_5 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 421.0
DTH2_k127_9155658_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 404.0
DTH2_k127_9155658_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 319.0
DTH2_k127_9155658_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000006052 221.0
DTH2_k127_9155658_9 - - - - 0.00000000000000000000000000000000000000000000000006849 204.0
DTH2_k127_9158626_0 PGAP1-like protein - - - 2.247e-280 869.0
DTH2_k127_9158626_1 Tripartite tricarboxylate transporter TctA family K07793 - - 4.655e-267 829.0
DTH2_k127_9158626_10 Protein of unknown function (DUF2721) - - - 0.0000000000000006051 79.0
DTH2_k127_9158626_11 T4-like virus tail tube protein gp19 - - - 0.0000168 52.0
DTH2_k127_9158626_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 532.0
DTH2_k127_9158626_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 522.0
DTH2_k127_9158626_4 Tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 447.0
DTH2_k127_9158626_5 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 394.0
DTH2_k127_9158626_6 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 338.0
DTH2_k127_9158626_7 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002719 266.0
DTH2_k127_9158626_8 Pfam:DUF3380 - - - 0.000000000000000000000000000000000000000000000000000000000000000002178 235.0
DTH2_k127_9158626_9 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000251 186.0
DTH2_k127_91644_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1387.0
DTH2_k127_91644_1 DNA helicase K03657 - 3.6.4.12 0.0 1050.0
DTH2_k127_91644_2 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000006115 258.0
DTH2_k127_91644_3 Sporulation related domain - - - 0.000000000000000000000000000000000000000000008201 188.0
DTH2_k127_91644_4 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000002201 130.0
DTH2_k127_91644_5 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000001512 132.0
DTH2_k127_91644_6 - - - - 0.00001312 54.0
DTH2_k127_91644_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00004244 54.0
DTH2_k127_9193233_0 Peptidase family M13 K07386 - - 2.312e-216 695.0
DTH2_k127_9193233_1 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 473.0
DTH2_k127_9193233_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 418.0
DTH2_k127_9193233_3 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 364.0
DTH2_k127_9193233_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001578 258.0
DTH2_k127_9193233_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000008971 240.0
DTH2_k127_9193233_6 PFAM von Willebrand factor type A K02448 - - 0.0000000000000000000000000003519 125.0
DTH2_k127_9205205_0 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 2.634e-239 767.0
DTH2_k127_9205205_1 COG0569 K transport systems, NAD-binding component K03499 - - 1.764e-197 627.0
DTH2_k127_9205205_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 505.0
DTH2_k127_9205205_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000002002 259.0
DTH2_k127_9205205_4 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002603 256.0
DTH2_k127_9205205_5 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000932 159.0
DTH2_k127_9278196_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 3.345e-317 989.0
DTH2_k127_9278196_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 4.596e-273 855.0
DTH2_k127_9278196_10 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003384 257.0
DTH2_k127_9278196_11 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001102 238.0
DTH2_k127_9278196_12 ribonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000002482 216.0
DTH2_k127_9278196_13 DSBA Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000399 213.0
DTH2_k127_9278196_14 Glutathione-dependent formaldehyde-activating protein - - - 0.0000000000000000000000000000000000000000000167 165.0
DTH2_k127_9278196_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000002874 161.0
DTH2_k127_9278196_16 positive regulation of growth - - - 0.00000000000000000000000003579 109.0
DTH2_k127_9278196_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000009201 65.0
DTH2_k127_9278196_18 protein domain associated with - - - 0.000000000009521 66.0
DTH2_k127_9278196_2 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.231e-255 795.0
DTH2_k127_9278196_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 7.095e-205 648.0
DTH2_k127_9278196_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 547.0
DTH2_k127_9278196_5 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 396.0
DTH2_k127_9278196_6 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 371.0
DTH2_k127_9278196_7 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 335.0
DTH2_k127_9278196_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 301.0
DTH2_k127_9278196_9 response regulator K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 285.0
DTH2_k127_9279386_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 584.0
DTH2_k127_9279386_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 420.0
DTH2_k127_9279386_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 346.0
DTH2_k127_9279386_3 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 302.0
DTH2_k127_9279386_4 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000269 261.0
DTH2_k127_9279386_5 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001269 266.0
DTH2_k127_9279386_6 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000004145 184.0
DTH2_k127_9339466_0 response regulator K02481 - - 1.574e-242 764.0
DTH2_k127_9339466_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 580.0
DTH2_k127_9339466_2 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 403.0
DTH2_k127_9339466_3 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 372.0
DTH2_k127_9339466_4 response regulator - - - 0.000000000000008507 76.0
DTH2_k127_9354778_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.164e-212 664.0
DTH2_k127_9354778_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 522.0
DTH2_k127_9354778_2 Phenylacetic acid degradation protein PaaY K02617,K08279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 290.0
DTH2_k127_9392470_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.469e-202 640.0
DTH2_k127_9392470_1 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 383.0
DTH2_k127_9392470_2 - - - - 0.000000000000000000000000000000001754 135.0
DTH2_k127_9404367_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.366e-253 785.0
DTH2_k127_9404367_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.234e-241 748.0
DTH2_k127_9404367_10 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 376.0
DTH2_k127_9404367_11 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 379.0
DTH2_k127_9404367_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 327.0
DTH2_k127_9404367_13 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 285.0
DTH2_k127_9404367_14 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000005053 197.0
DTH2_k127_9404367_15 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000002034 192.0
DTH2_k127_9404367_16 diol metabolic process K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000412 175.0
DTH2_k127_9404367_17 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000000000000000000002141 133.0
DTH2_k127_9404367_18 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000007939 117.0
DTH2_k127_9404367_19 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.0000000000000000007821 100.0
DTH2_k127_9404367_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.125e-203 638.0
DTH2_k127_9404367_20 Entericidin EcnA/B family - - - 0.0000002232 55.0
DTH2_k127_9404367_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 3.538e-195 613.0
DTH2_k127_9404367_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 601.0
DTH2_k127_9404367_5 PFAM Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 507.0
DTH2_k127_9404367_6 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 510.0
DTH2_k127_9404367_7 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 403.0
DTH2_k127_9404367_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 385.0
DTH2_k127_9404367_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 373.0
DTH2_k127_9431745_0 Cytochrome d1, heme K15864 - 1.7.2.1,1.7.99.1 0.0 1011.0
DTH2_k127_9431745_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 469.0
DTH2_k127_9431745_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 460.0
DTH2_k127_9431745_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090,K18916 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81,1.20.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 415.0
DTH2_k127_9431745_4 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 393.0
DTH2_k127_9431745_5 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000001273 219.0
DTH2_k127_9431745_6 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000144 211.0
DTH2_k127_9431745_7 Haem-degrading K11477 - - 0.0000000000000000000000000000000000004749 149.0
DTH2_k127_9431745_8 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.0000000000000000000000002732 121.0
DTH2_k127_947843_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0 1204.0
DTH2_k127_947843_1 AMP-binding enzyme C-terminal domain - - - 4.296e-201 639.0
DTH2_k127_947843_2 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002678 287.0
DTH2_k127_947843_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000006786 126.0
DTH2_k127_947843_4 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K07216 - - 0.0000000003685 64.0
DTH2_k127_9488986_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 8.742e-263 820.0
DTH2_k127_9488986_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 593.0
DTH2_k127_9488986_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 573.0
DTH2_k127_9488986_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 543.0
DTH2_k127_9488986_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 511.0
DTH2_k127_9488986_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 496.0
DTH2_k127_9488986_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000007493 194.0
DTH2_k127_9488986_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000005387 97.0
DTH2_k127_9517607_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1473.0
DTH2_k127_9517607_1 DNA polymerase III K02342 - 2.7.7.7 1.055e-224 719.0
DTH2_k127_9517607_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 5.315e-209 659.0
DTH2_k127_9517607_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 398.0
DTH2_k127_9517607_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 394.0
DTH2_k127_9517607_5 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 293.0
DTH2_k127_9517607_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000001715 208.0
DTH2_k127_9517607_7 protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000000000002603 202.0
DTH2_k127_9517607_8 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000006424 184.0
DTH2_k127_9517607_9 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000002417 182.0
DTH2_k127_9567570_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1072.0
DTH2_k127_9567570_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 1.922e-287 905.0
DTH2_k127_9567570_10 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 287.0
DTH2_k127_9567570_11 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000229 281.0
DTH2_k127_9567570_12 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006026 284.0
DTH2_k127_9567570_13 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002767 268.0
DTH2_k127_9567570_14 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007065 259.0
DTH2_k127_9567570_15 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000192 215.0
DTH2_k127_9567570_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000004432 201.0
DTH2_k127_9567570_17 Guanyl-specific ribonuclease Sa - - - 0.0000000000000000000000000000000000000004832 153.0
DTH2_k127_9567570_18 Barstar (barnase inhibitor) - - - 0.0000000000000000000000000000005845 128.0
DTH2_k127_9567570_19 Putative regulatory protein - - - 0.000000000000000000000000000001967 123.0
DTH2_k127_9567570_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 592.0
DTH2_k127_9567570_3 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 563.0
DTH2_k127_9567570_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 559.0
DTH2_k127_9567570_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 548.0
DTH2_k127_9567570_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 516.0
DTH2_k127_9567570_7 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 491.0
DTH2_k127_9567570_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 420.0
DTH2_k127_9567570_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 292.0
DTH2_k127_9587999_0 DNA polymerase K02337 - 2.7.7.7 0.0 1381.0
DTH2_k127_9587999_1 COG1982 Arginine lysine ornithine decarboxylases K01584 - 4.1.1.19 0.0 1378.0
DTH2_k127_9587999_10 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 377.0
DTH2_k127_9587999_11 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814,K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 324.0
DTH2_k127_9587999_12 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 320.0
DTH2_k127_9587999_13 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 293.0
DTH2_k127_9587999_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002089 282.0
DTH2_k127_9587999_15 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008364 257.0
DTH2_k127_9587999_16 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001576 251.0
DTH2_k127_9587999_17 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000000007912 211.0
DTH2_k127_9587999_18 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000002096 216.0
DTH2_k127_9587999_19 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000008359 196.0
DTH2_k127_9587999_2 PFAM malic K00029 - 1.1.1.40 0.0 1127.0
DTH2_k127_9587999_20 Enoyl-CoA hydratase/isomerase K13816 - - 0.0000000000000000000000000000000000000000000001289 180.0
DTH2_k127_9587999_21 PIN domain - - - 0.00000000000000000000000000000000272 135.0
DTH2_k127_9587999_22 SpoVT / AbrB like domain K07172 - - 0.0000000000000000000000000007769 114.0
DTH2_k127_9587999_23 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000003565 94.0
DTH2_k127_9587999_24 PFAM Cytochrome C - - - 0.00000000000005015 76.0
DTH2_k127_9587999_25 Transcriptional regulator - - - 0.0000000000003999 71.0
DTH2_k127_9587999_26 PIN domain - - - 0.000000000001898 68.0
DTH2_k127_9587999_28 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0002197 47.0
DTH2_k127_9587999_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1081.0
DTH2_k127_9587999_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 565.0
DTH2_k127_9587999_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 545.0
DTH2_k127_9587999_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 535.0
DTH2_k127_9587999_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 498.0
DTH2_k127_9587999_8 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 410.0
DTH2_k127_9587999_9 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 378.0
DTH2_k127_9618425_0 LVIVD repeat - - - 0.0 1718.0
DTH2_k127_9618425_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1303.0
DTH2_k127_9618425_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 5.277e-301 943.0
DTH2_k127_9618425_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 611.0
DTH2_k127_9618425_4 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 398.0
DTH2_k127_9618425_5 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 304.0
DTH2_k127_9618425_6 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.0000000000000000000000000000000000000000000000000001034 188.0
DTH2_k127_9651633_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1831.0
DTH2_k127_9651633_1 Heat shock 70 kDa protein K04043 - - 0.0 1076.0
DTH2_k127_9651633_10 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005956 269.0
DTH2_k127_9651633_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002941 250.0
DTH2_k127_9651633_12 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006136 246.0
DTH2_k127_9651633_13 Thioredoxin-like domain K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000001622 229.0
DTH2_k127_9651633_14 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000136 226.0
DTH2_k127_9651633_15 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000124 226.0
DTH2_k127_9651633_16 Domain of unknown function (DUF4149) - - - 0.0000000000000000000000000000000000000000000000003808 179.0
DTH2_k127_9651633_17 PFAM thioesterase superfamily protein K19222 - 3.1.2.28 0.0000000000000000000000000000000000000000000001436 177.0
DTH2_k127_9651633_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000004785 136.0
DTH2_k127_9651633_19 CRS1_YhbY K07574 - - 0.00000000000000000000000000000004322 129.0
DTH2_k127_9651633_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1039.0
DTH2_k127_9651633_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 4.189e-199 624.0
DTH2_k127_9651633_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 590.0
DTH2_k127_9651633_5 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 565.0
DTH2_k127_9651633_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 501.0
DTH2_k127_9651633_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 499.0
DTH2_k127_9651633_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 395.0
DTH2_k127_9651633_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 388.0
DTH2_k127_9822318_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.087e-223 698.0
DTH2_k127_9822318_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.051e-211 666.0
DTH2_k127_9822318_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 3.772e-207 651.0
DTH2_k127_9822318_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.537e-205 652.0
DTH2_k127_9822318_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 589.0
DTH2_k127_9822318_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 434.0
DTH2_k127_9822318_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004962 251.0
DTH2_k127_9822318_7 type 4 pilus biogenesis protein K02656 - - 0.00000000000000000000000000000000000000000000000000000000000002728 228.0
DTH2_k127_9822318_8 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000001361 179.0
DTH2_k127_9822318_9 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000001345 148.0
DTH2_k127_9832657_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 1148.0
DTH2_k127_9832657_1 Acts as a magnesium transporter K06213 - - 2e-227 713.0
DTH2_k127_9832657_10 response regulator receiver K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
DTH2_k127_9832657_11 PFAM Carbohydrate-selective porin OprB K07267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005556 264.0
DTH2_k127_9832657_12 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000001381 220.0
DTH2_k127_9832657_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000003364 217.0
DTH2_k127_9832657_14 RESPONSE REGULATOR receiver K02658 - - 0.000000000000000000000000000000000000000000000000000033 189.0
DTH2_k127_9832657_15 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000004798 186.0
DTH2_k127_9832657_16 Small Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000000000000002583 175.0
DTH2_k127_9832657_17 Chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000000003674 179.0
DTH2_k127_9832657_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000002552 128.0
DTH2_k127_9832657_19 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000008733 111.0
DTH2_k127_9832657_2 Aminotransferase K01845 - 5.4.3.8 2.767e-218 685.0
DTH2_k127_9832657_20 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000002095 119.0
DTH2_k127_9832657_21 - - - - 0.000001035 58.0
DTH2_k127_9832657_3 Methyl-accepting chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 550.0
DTH2_k127_9832657_4 7TM diverse intracellular signalling - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 541.0
DTH2_k127_9832657_5 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 445.0
DTH2_k127_9832657_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 409.0
DTH2_k127_9832657_7 His Kinase A (phosphoacceptor) domain K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 355.0
DTH2_k127_9832657_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 325.0
DTH2_k127_9832657_9 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 280.0
DTH2_k127_9839967_0 Radical SAM superfamily K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 583.0
DTH2_k127_9839967_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 396.0
DTH2_k127_9839967_11 - - - - 0.00000000005147 65.0
DTH2_k127_9839967_12 NYN domain - - - 0.00000001195 56.0
DTH2_k127_9839967_2 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 302.0
DTH2_k127_9839967_3 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000009585 188.0
DTH2_k127_9839967_4 Belongs to the DsbB family K03611 - - 0.0000000000000000000000000000000000000000000000004057 180.0
DTH2_k127_9839967_5 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000002928 178.0
DTH2_k127_9839967_8 - - - - 0.00000000000000000000003576 102.0
DTH2_k127_9839967_9 Las17-binding protein actin regulator - - - 0.00000000000000000001928 94.0
DTH2_k127_986239_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1080.0
DTH2_k127_986239_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1028.0
DTH2_k127_986239_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002981 258.0
DTH2_k127_986239_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000006318 206.0
DTH2_k127_986239_12 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000001939 188.0
DTH2_k127_986239_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000817 175.0
DTH2_k127_986239_14 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000002192 173.0
DTH2_k127_986239_15 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000133 100.0
DTH2_k127_986239_16 - - - - 0.000000000003369 68.0
DTH2_k127_986239_17 - - - - 0.000003363 50.0
DTH2_k127_986239_2 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 575.0
DTH2_k127_986239_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 560.0
DTH2_k127_986239_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 381.0
DTH2_k127_986239_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 366.0
DTH2_k127_986239_6 RNA polymerase sigma K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 344.0
DTH2_k127_986239_7 lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 318.0
DTH2_k127_986239_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 297.0
DTH2_k127_986239_9 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
DTH2_k127_9869716_0 AcrB/AcrD/AcrF family K07239 - - 0.0 1724.0
DTH2_k127_9869716_1 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.0 1015.0
DTH2_k127_9869716_10 - - - - 0.0000000000000000000000000000000000000000000003251 171.0
DTH2_k127_9869716_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000001884 132.0
DTH2_k127_9869716_12 - - - - 0.00000000000000000000000000001443 126.0
DTH2_k127_9869716_2 P-type ATPase K17686 - 3.6.3.54 3.189e-232 725.0
DTH2_k127_9869716_3 Member of a two-component regulatory system K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 587.0
DTH2_k127_9869716_4 Transcriptional regulatory protein, C terminal K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 412.0
DTH2_k127_9869716_5 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 391.0
DTH2_k127_9869716_6 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 379.0
DTH2_k127_9869716_7 Cd(II) Pb(II)-responsive transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002798 223.0
DTH2_k127_9869716_8 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000906 233.0
DTH2_k127_9869716_9 Protein of unknown function (DUF1090) - - - 0.000000000000000000000000000000000000000000000296 173.0
DTH2_k127_9917891_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.148e-248 775.0
DTH2_k127_9917891_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 8.473e-226 709.0
DTH2_k127_9917891_10 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 402.0
DTH2_k127_9917891_11 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 354.0
DTH2_k127_9917891_12 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 328.0
DTH2_k127_9917891_13 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 317.0
DTH2_k127_9917891_14 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001314 291.0
DTH2_k127_9917891_15 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008137 280.0
DTH2_k127_9917891_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000002673 268.0
DTH2_k127_9917891_17 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000005196 192.0
DTH2_k127_9917891_18 ferredoxin - - - 0.000000000000000000000000000000000000000000000133 170.0
DTH2_k127_9917891_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000002972 136.0
DTH2_k127_9917891_2 Domain of unknown function (DUF4143) K07133 - - 3.883e-205 643.0
DTH2_k127_9917891_20 MazG-like family - - - 0.000000000000000000000000000000004431 130.0
DTH2_k127_9917891_21 PIN domain - - - 0.00000000000000000000000000001938 123.0
DTH2_k127_9917891_22 ThiS family K03154 - - 0.00000000000000000001099 92.0
DTH2_k127_9917891_3 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 578.0
DTH2_k127_9917891_4 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 548.0
DTH2_k127_9917891_5 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 535.0
DTH2_k127_9917891_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 513.0
DTH2_k127_9917891_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 497.0
DTH2_k127_9917891_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 452.0
DTH2_k127_9917891_9 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 451.0
DTH2_k127_9919941_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 439.0
DTH2_k127_9919941_1 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 335.0
DTH2_k127_9919941_2 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000000000000000000000000001107 159.0
DTH2_k127_9919941_3 Transcriptional regulator - - - 0.00000000000000000000005909 100.0
DTH2_k127_9969848_0 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 537.0
DTH2_k127_9969848_1 Short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 384.0
DTH2_k127_9969848_3 Mediates the transbilayer movement of Und-PP-GlcNAc- ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA) K03328,K16693 - - 0.0001038 54.0