Overview

ID MAG00766
Name DTH2_bin.24
Sample SMP0023
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class EX4484-6
Order EX4484-6
Family EX4484-6
Genus
Species
Assembly information
Completeness (%) 88.72
Contamination (%) 0.06
GC content (%) 56.0
N50 (bp) 20,839
Genome size (bp) 2,416,545

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1594

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10086981_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 447.0
DTH2_k127_10086981_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 398.0
DTH2_k127_10086981_10 COG1522 Transcriptional regulators - - - 0.0000000000000001626 91.0
DTH2_k127_10086981_11 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000002236 61.0
DTH2_k127_10086981_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 323.0
DTH2_k127_10086981_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000174 287.0
DTH2_k127_10086981_4 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000002208 229.0
DTH2_k127_10086981_5 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000004418 168.0
DTH2_k127_10086981_6 Acyltransferase - - - 0.00000000000000000000000000000002275 138.0
DTH2_k127_10086981_7 polysaccharide biosynthetic process - - - 0.000000000000000000001067 109.0
DTH2_k127_10086981_8 - - - - 0.0000000000000000000015 98.0
DTH2_k127_10086981_9 Glycosyltransferase Family 4 - - - 0.0000000000000000003966 100.0
DTH2_k127_10087817_0 Glycosyltransferase Family 4 K14949 - 2.7.11.1 0.000000000000000000000000002815 123.0
DTH2_k127_10087817_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000001772 63.0
DTH2_k127_10756_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 460.0
DTH2_k127_10756_1 Fungalysin metallopeptidase (M36) - - - 0.00000006837 66.0
DTH2_k127_10756_2 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.0000002824 64.0
DTH2_k127_10756_3 Periplasmic copper-binding protein (NosD) - - - 0.00002471 59.0
DTH2_k127_1097931_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.2e-318 1005.0
DTH2_k127_1097931_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 515.0
DTH2_k127_1097931_10 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 312.0
DTH2_k127_1097931_11 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 298.0
DTH2_k127_1097931_12 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000008929 243.0
DTH2_k127_1097931_13 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000006072 223.0
DTH2_k127_1097931_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000009976 211.0
DTH2_k127_1097931_15 PFAM B3 4 domain - - - 0.0000000000000000000000000000000000000000000003605 178.0
DTH2_k127_1097931_16 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000006775 169.0
DTH2_k127_1097931_17 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000001672 167.0
DTH2_k127_1097931_18 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000002401 145.0
DTH2_k127_1097931_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000001478 149.0
DTH2_k127_1097931_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 488.0
DTH2_k127_1097931_20 OsmC-like protein K07397 - - 0.00000000000000000000000000000002152 131.0
DTH2_k127_1097931_21 Maf-like protein K06287 - - 0.0000000000000000000000000001981 121.0
DTH2_k127_1097931_22 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000001377 114.0
DTH2_k127_1097931_23 - - - - 0.00000000000000000000001447 103.0
DTH2_k127_1097931_24 Ribonuclease K03469 - 3.1.26.4 0.000000000000000000002973 100.0
DTH2_k127_1097931_25 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000006835 83.0
DTH2_k127_1097931_26 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000003661 76.0
DTH2_k127_1097931_27 PFAM SMP-30 Gluconolaconase - - - 0.00000000003915 77.0
DTH2_k127_1097931_28 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000002447 59.0
DTH2_k127_1097931_29 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.000004043 58.0
DTH2_k127_1097931_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 479.0
DTH2_k127_1097931_30 Domain in cystathionine beta-synthase and other proteins. - - - 0.00001185 57.0
DTH2_k127_1097931_31 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0001173 53.0
DTH2_k127_1097931_4 PAS domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 464.0
DTH2_k127_1097931_5 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 424.0
DTH2_k127_1097931_6 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 417.0
DTH2_k127_1097931_7 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 420.0
DTH2_k127_1097931_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 372.0
DTH2_k127_1097931_9 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 362.0
DTH2_k127_1117_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.267e-291 917.0
DTH2_k127_1117_1 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000006938 188.0
DTH2_k127_1117_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000003064 181.0
DTH2_k127_1117_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000001122 124.0
DTH2_k127_1117_4 Helix-turn-helix domain - - - 0.00000000000002991 76.0
DTH2_k127_1117_5 Subtilase family - - - 0.00000008825 55.0
DTH2_k127_1157499_0 S-layer homology domain K17734 - - 0.00000000000000000000000000000000000000000000000000267 207.0
DTH2_k127_1157499_1 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.000000000000000000000000000000000003982 160.0
DTH2_k127_1157499_2 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.000000000000000000000000000002884 141.0
DTH2_k127_1157499_3 - - - - 0.000000000000000000000000000006586 140.0
DTH2_k127_1157499_4 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000004737 88.0
DTH2_k127_1157499_5 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.000000000000003277 91.0
DTH2_k127_1157499_6 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.000000000000004314 91.0
DTH2_k127_1210023_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0050897,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 487.0
DTH2_k127_1210023_1 UPF0313 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 431.0
DTH2_k127_1210023_2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 307.0
DTH2_k127_1210023_3 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000001544 205.0
DTH2_k127_1210023_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000002121 190.0
DTH2_k127_1210023_5 - - - - 0.00000000000000000000000000000002094 134.0
DTH2_k127_1210023_6 - - - - 0.0000000005384 63.0
DTH2_k127_1210023_7 - - - - 0.0000000107 62.0
DTH2_k127_1210023_8 AAA domain - - - 0.0000005911 62.0
DTH2_k127_1319356_0 PFAM TM1410 hypothetical-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 316.0
DTH2_k127_1319356_1 E3 Ubiquitin ligase - - - 0.000004515 57.0
DTH2_k127_1319356_2 Domain of unknown function (DUF4870) K09940 - - 0.0003476 48.0
DTH2_k127_139956_0 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003935 289.0
DTH2_k127_139956_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007599 295.0
DTH2_k127_139956_2 Glutamine synthetase, beta-Grasp domain K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009142 272.0
DTH2_k127_139956_3 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000005625 179.0
DTH2_k127_139956_4 PFAM pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.0000000000000000000000001512 120.0
DTH2_k127_139956_5 - - - - 0.00000000000000000000003574 110.0
DTH2_k127_139956_6 HELICc2 K07464,K10844 - 3.1.12.1,3.6.4.12 0.00000000000003265 86.0
DTH2_k127_139956_7 AsnC family transcriptional regulator K03719 - - 0.00009621 53.0
DTH2_k127_139956_8 helix_turn_helix ASNC type - - - 0.0005325 51.0
DTH2_k127_1438237_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
DTH2_k127_1438237_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000001516 139.0
DTH2_k127_1438237_2 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000834 130.0
DTH2_k127_1438237_3 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000008757 102.0
DTH2_k127_1438237_4 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000004642 93.0
DTH2_k127_1438237_5 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.0000000001079 63.0
DTH2_k127_1470444_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001107 300.0
DTH2_k127_1470444_1 PFAM glycoside hydrolase, family 16 - - - 0.000000001634 72.0
DTH2_k127_149445_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 619.0
DTH2_k127_149445_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 445.0
DTH2_k127_149445_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 393.0
DTH2_k127_149445_3 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 331.0
DTH2_k127_149445_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000008372 173.0
DTH2_k127_149445_5 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.0000000000000000000000003556 107.0
DTH2_k127_149445_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000007099 94.0
DTH2_k127_149445_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000002443 50.0
DTH2_k127_1506901_0 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.00000000000000000000000000000000000000004277 155.0
DTH2_k127_1506901_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000004814 162.0
DTH2_k127_1506901_2 Methyltransferase type 11 - - - 0.0000001252 63.0
DTH2_k127_1506901_3 TIGRFAM AMP nucleosidase K01241 - 3.2.2.4 0.0000001555 61.0
DTH2_k127_158021_0 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000221 248.0
DTH2_k127_158021_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000002746 224.0
DTH2_k127_158021_11 PKD domain - - - 0.0005087 53.0
DTH2_k127_158021_2 Transcriptional regulator K02019,K03574,K03750,K07219 - 2.10.1.1,3.6.1.55 0.00000000000000003237 89.0
DTH2_k127_158021_3 Band 7 protein K07192 - - 0.00000000000000003912 89.0
DTH2_k127_158021_4 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000005539 83.0
DTH2_k127_158021_5 self proteolysis - - - 0.0000000000002013 85.0
DTH2_k127_158021_7 - - - - 0.0000000006833 62.0
DTH2_k127_158021_8 ABC-type cobalt transport system, permease component K16925 - - 0.000001194 61.0
DTH2_k127_158021_9 Bacterial Ig-like domain (group 3) K20276 - - 0.000003028 62.0
DTH2_k127_16308_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 6.429e-273 875.0
DTH2_k127_16308_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.525e-247 797.0
DTH2_k127_16308_10 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001102 255.0
DTH2_k127_16308_11 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006903 246.0
DTH2_k127_16308_12 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000002667 220.0
DTH2_k127_16308_13 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000005575 177.0
DTH2_k127_16308_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000003504 181.0
DTH2_k127_16308_15 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000369 178.0
DTH2_k127_16308_16 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000001571 151.0
DTH2_k127_16308_17 pfkB family carbohydrate kinase K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.0000000000000000000000000000008179 134.0
DTH2_k127_16308_18 molybdopterin binding domain - - - 0.00000000000000000000000000004085 128.0
DTH2_k127_16308_19 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000001143 116.0
DTH2_k127_16308_2 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 8.212e-214 672.0
DTH2_k127_16308_20 PFAM regulatory protein AsnC Lrp family - - - 0.000000281 63.0
DTH2_k127_16308_21 transcriptional K03718 - - 0.0001787 53.0
DTH2_k127_16308_22 transcription regulator activity - - - 0.0004377 51.0
DTH2_k127_16308_23 Domain of unknown function DUF11 - - - 0.0008264 52.0
DTH2_k127_16308_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.2,1.4.1.3,1.4.1.4 3.427e-204 647.0
DTH2_k127_16308_4 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 552.0
DTH2_k127_16308_5 Pyruvate phosphate dikinase, PEP pyruvate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 542.0
DTH2_k127_16308_6 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 307.0
DTH2_k127_16308_7 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 314.0
DTH2_k127_16308_8 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 269.0
DTH2_k127_16308_9 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001134 258.0
DTH2_k127_1687797_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 525.0
DTH2_k127_1687797_1 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 484.0
DTH2_k127_1687797_10 4Fe-4S binding domain protein - - - 0.0000000000000000000000000000000000004322 153.0
DTH2_k127_1687797_11 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000003149 145.0
DTH2_k127_1687797_12 PQQ enzyme repeat - - - 0.00000000000000000000000000000000006899 149.0
DTH2_k127_1687797_13 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000005458 140.0
DTH2_k127_1687797_14 PQQ-like domain - - - 0.00000000000000000000000002111 125.0
DTH2_k127_1687797_15 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000001052 71.0
DTH2_k127_1687797_16 transferase activity, transferring glycosyl groups - - - 0.00000009616 64.0
DTH2_k127_1687797_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 305.0
DTH2_k127_1687797_3 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 300.0
DTH2_k127_1687797_4 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002302 252.0
DTH2_k127_1687797_5 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000004599 248.0
DTH2_k127_1687797_6 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000003626 222.0
DTH2_k127_1687797_7 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000006241 210.0
DTH2_k127_1687797_8 UMP catabolic process K01101,K02101,K02566 - 3.1.3.41 0.0000000000000000000000000000000000000000000000144 183.0
DTH2_k127_1687797_9 WD40 repeats - - - 0.0000000000000000000000000000000000001095 157.0
DTH2_k127_1709531_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.268e-225 706.0
DTH2_k127_1709531_1 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005019 267.0
DTH2_k127_1709531_10 response regulator - - - 0.0000000000000003431 85.0
DTH2_k127_1709531_11 COG1404 Subtilisin-like serine proteases K13276 - - 0.000000000008689 77.0
DTH2_k127_1709531_12 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.000002368 60.0
DTH2_k127_1709531_2 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004877 261.0
DTH2_k127_1709531_3 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000009279 264.0
DTH2_k127_1709531_4 PFAM Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000001244 235.0
DTH2_k127_1709531_5 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000009766 231.0
DTH2_k127_1709531_6 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000005427 185.0
DTH2_k127_1709531_7 PFAM GAF domain K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000005128 170.0
DTH2_k127_1709531_8 Rubrerythrin - - - 0.000000000000000000000000000000000001161 144.0
DTH2_k127_1709531_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000001665 145.0
DTH2_k127_1765573_0 hyaluronan metabolic process - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.000000000000000000000000000000000000000000002912 183.0
DTH2_k127_1765573_1 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000000000000001861 181.0
DTH2_k127_1765573_2 nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module K07060 - - 0.0000000000000001645 88.0
DTH2_k127_1765573_3 Oligopeptide transporter, OPT family - - - 0.000000003337 66.0
DTH2_k127_1765573_4 PFAM regulatory protein, ArsR - - - 0.00000001916 67.0
DTH2_k127_1805386_0 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 557.0
DTH2_k127_1805386_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 438.0
DTH2_k127_1805386_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000003506 157.0
DTH2_k127_1805386_3 acetyltransferase, GNAT family - - - 0.0000000000000000000000000001842 121.0
DTH2_k127_1805386_4 Endonuclease Exonuclease Phosphatase - - - 0.000000000005648 80.0
DTH2_k127_1805386_5 Endonuclease Exonuclease Phosphatase - - - 0.0000002595 65.0
DTH2_k127_19123_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007677 254.0
DTH2_k127_19123_1 - - - - 0.00000000000000000000000000000007278 130.0
DTH2_k127_19123_2 Cellulose binding domain - - - 0.000001351 62.0
DTH2_k127_1975979_0 E1-E2 ATPase K17686 - 3.6.3.54 4.193e-284 895.0
DTH2_k127_1975979_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 311.0
DTH2_k127_1975979_10 pfam yhs - - - 0.0000000000000000000765 89.0
DTH2_k127_1975979_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.00000000000000009918 85.0
DTH2_k127_1975979_12 binds to the 23S rRNA K02921 - - 0.0000000000000001641 83.0
DTH2_k127_1975979_13 PRC-barrel domain - - - 0.0000000000000009176 82.0
DTH2_k127_1975979_14 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000001245 58.0
DTH2_k127_1975979_15 transcriptional regulator K05800 - - 0.0001093 52.0
DTH2_k127_1975979_16 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000458 48.0
DTH2_k127_1975979_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 312.0
DTH2_k127_1975979_3 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009289 260.0
DTH2_k127_1975979_4 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000104 190.0
DTH2_k127_1975979_5 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000001247 184.0
DTH2_k127_1975979_6 DHH family - - - 0.000000000000000000000000000000003802 141.0
DTH2_k127_1975979_7 PFAM TfoX N-terminal domain K07343 - - 0.0000000000000000000000000008781 115.0
DTH2_k127_1975979_8 Belongs to the peptidase S8 family - - - 0.00000000000000000000000001479 127.0
DTH2_k127_1975979_9 anaphase-promoting complex binding K06922 - - 0.000000000000000000000002585 121.0
DTH2_k127_2004895_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000447 282.0
DTH2_k127_2004895_1 Domain of unknown function (DUF4129) - - - 0.000043 58.0
DTH2_k127_2022054_0 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 480.0
DTH2_k127_2022054_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 421.0
DTH2_k127_2022054_2 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004068 282.0
DTH2_k127_2022054_3 - - - - 0.00000000000000000000000000000000000000000000000000000009506 201.0
DTH2_k127_2022054_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000002141 154.0
DTH2_k127_2022054_5 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000009465 135.0
DTH2_k127_2081300_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.098e-301 938.0
DTH2_k127_2081300_1 KH domain K07041 - - 2.05e-250 787.0
DTH2_k127_2081300_10 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 433.0
DTH2_k127_2081300_11 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 421.0
DTH2_k127_2081300_12 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 417.0
DTH2_k127_2081300_13 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 370.0
DTH2_k127_2081300_14 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 355.0
DTH2_k127_2081300_15 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 343.0
DTH2_k127_2081300_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 342.0
DTH2_k127_2081300_17 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 325.0
DTH2_k127_2081300_18 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 325.0
DTH2_k127_2081300_19 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 312.0
DTH2_k127_2081300_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.792e-214 696.0
DTH2_k127_2081300_20 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 289.0
DTH2_k127_2081300_21 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007563 285.0
DTH2_k127_2081300_22 Has ATPase and non-specific DNA-binding activities K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003565 295.0
DTH2_k127_2081300_23 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001572 278.0
DTH2_k127_2081300_24 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000032 269.0
DTH2_k127_2081300_25 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
DTH2_k127_2081300_26 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001781 247.0
DTH2_k127_2081300_27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000004088 247.0
DTH2_k127_2081300_28 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000001139 239.0
DTH2_k127_2081300_29 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000176 242.0
DTH2_k127_2081300_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 517.0
DTH2_k127_2081300_30 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000004165 237.0
DTH2_k127_2081300_31 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000008197 213.0
DTH2_k127_2081300_32 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000002904 204.0
DTH2_k127_2081300_33 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000001835 209.0
DTH2_k127_2081300_34 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000002819 205.0
DTH2_k127_2081300_35 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000004079 210.0
DTH2_k127_2081300_36 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000003648 213.0
DTH2_k127_2081300_37 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000003921 191.0
DTH2_k127_2081300_38 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000006775 197.0
DTH2_k127_2081300_39 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000975 188.0
DTH2_k127_2081300_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 516.0
DTH2_k127_2081300_40 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000003904 182.0
DTH2_k127_2081300_41 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000005207 184.0
DTH2_k127_2081300_42 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000002451 178.0
DTH2_k127_2081300_43 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000001302 181.0
DTH2_k127_2081300_44 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000004175 170.0
DTH2_k127_2081300_45 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000002112 171.0
DTH2_k127_2081300_46 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001609 157.0
DTH2_k127_2081300_47 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001912 172.0
DTH2_k127_2081300_48 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000003159 158.0
DTH2_k127_2081300_49 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000002848 167.0
DTH2_k127_2081300_5 lysyl-tRNA aminoacylation K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 490.0
DTH2_k127_2081300_50 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000003141 150.0
DTH2_k127_2081300_51 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000009397 154.0
DTH2_k127_2081300_52 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000000000000000003613 142.0
DTH2_k127_2081300_53 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000004161 143.0
DTH2_k127_2081300_54 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000007758 144.0
DTH2_k127_2081300_55 - - - - 0.00000000000000000000000000000006931 136.0
DTH2_k127_2081300_56 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000001705 132.0
DTH2_k127_2081300_57 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000008301 139.0
DTH2_k127_2081300_58 Uncharacterised protein family (UPF0179) K09730 - - 0.000000000000000000000000000001577 125.0
DTH2_k127_2081300_59 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000007666 113.0
DTH2_k127_2081300_6 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 479.0
DTH2_k127_2081300_60 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000001012 119.0
DTH2_k127_2081300_61 Peptidase S8 - - - 0.00000000000000000000000001301 128.0
DTH2_k127_2081300_62 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000003094 109.0
DTH2_k127_2081300_63 - - - - 0.000000000000000000000004276 107.0
DTH2_k127_2081300_64 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000007601 104.0
DTH2_k127_2081300_65 Phosphopantetheine adenylyltransferase K02201 - 2.7.7.3 0.0000000000000000000002293 103.0
DTH2_k127_2081300_66 Rhomboid family K09650 - 3.4.21.105 0.00000000000000006341 92.0
DTH2_k127_2081300_67 Belongs to the ompA family K20276 - - 0.0000000000000006591 93.0
DTH2_k127_2081300_68 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.000000000000003649 91.0
DTH2_k127_2081300_69 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000001908 88.0
DTH2_k127_2081300_7 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 469.0
DTH2_k127_2081300_70 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000004696 83.0
DTH2_k127_2081300_71 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00000000000008809 74.0
DTH2_k127_2081300_72 PFAM Ribosomal protein S27E K02978 - - 0.000000000004606 71.0
DTH2_k127_2081300_73 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000006072 68.0
DTH2_k127_2081300_74 cytochrome c biogenesis protein K06196 - - 0.000000000006818 79.0
DTH2_k127_2081300_75 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000002717 66.0
DTH2_k127_2081300_76 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000003419 72.0
DTH2_k127_2081300_77 protein conserved in archaea - - - 0.000000001103 72.0
DTH2_k127_2081300_78 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000001663 72.0
DTH2_k127_2081300_79 - - - - 0.00000000933 66.0
DTH2_k127_2081300_8 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 474.0
DTH2_k127_2081300_80 PFAM Fibronectin type III domain - - - 0.00000001695 68.0
DTH2_k127_2081300_81 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000007239 62.0
DTH2_k127_2081300_82 endo-1,4-beta-xylanase activity K21636 - 1.1.98.6 0.0000001167 66.0
DTH2_k127_2081300_83 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000001576 56.0
DTH2_k127_2081300_84 KaiC - - - 0.0000003827 60.0
DTH2_k127_2081300_85 Belongs to the peptidase S8 family - - - 0.0000008412 63.0
DTH2_k127_2081300_86 ThiS family K03154 - - 0.000003341 55.0
DTH2_k127_2081300_87 HNH endonuclease - - - 0.000004452 58.0
DTH2_k127_2081300_88 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000005074 60.0
DTH2_k127_2081300_89 - - - - 0.000008238 58.0
DTH2_k127_2081300_9 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 469.0
DTH2_k127_2081300_90 - - - - 0.00001271 50.0
DTH2_k127_2081300_91 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00001723 51.0
DTH2_k127_2081300_92 Conserved repeat domain - - - 0.000026 58.0
DTH2_k127_2081300_93 PKD domain - - - 0.00009731 56.0
DTH2_k127_2081300_94 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0001318 53.0
DTH2_k127_2081300_95 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0001549 52.0
DTH2_k127_2081300_96 PFAM peptidase M6, immune inhibitor A K09607 - - 0.0006206 53.0
DTH2_k127_2193376_0 Glycosyl transferase family group 2 K19003 - 2.4.1.336 0.00000000000000000000000000000000000000000000000000000000000000001854 244.0
DTH2_k127_2224420_0 Fibronectin type iii domain protein - - - 0.000003411 60.0
DTH2_k127_229004_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 548.0
DTH2_k127_229004_1 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 475.0
DTH2_k127_229004_10 Kelch - GO:0000003,GO:0000133,GO:0000278,GO:0000281,GO:0000746,GO:0000747,GO:0000755,GO:0000910,GO:0000935,GO:0001100,GO:0005575,GO:0005622,GO:0005623,GO:0005628,GO:0005737,GO:0005856,GO:0005874,GO:0005875,GO:0005881,GO:0005933,GO:0005934,GO:0005935,GO:0005937,GO:0005938,GO:0007049,GO:0007088,GO:0007096,GO:0007163,GO:0007346,GO:0008104,GO:0008150,GO:0008360,GO:0009987,GO:0010564,GO:0010639,GO:0010948,GO:0015630,GO:0016020,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022603,GO:0022604,GO:0030427,GO:0030428,GO:0031110,GO:0031111,GO:0031113,GO:0031115,GO:0031333,GO:0031500,GO:0032153,GO:0032155,GO:0032187,GO:0032231,GO:0032271,GO:0032272,GO:0032465,GO:0032505,GO:0032506,GO:0032878,GO:0032879,GO:0032886,GO:0032956,GO:0032970,GO:0032991,GO:0033036,GO:0033043,GO:0034613,GO:0035371,GO:0035838,GO:0035839,GO:0035840,GO:0036214,GO:0042763,GO:0042764,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043332,GO:0044087,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044463,GO:0044464,GO:0044703,GO:0044764,GO:0045786,GO:0045839,GO:0045930,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051049,GO:0051128,GO:0051129,GO:0051179,GO:0051285,GO:0051286,GO:0051301,GO:0051302,GO:0051493,GO:0051494,GO:0051641,GO:0051704,GO:0051726,GO:0051783,GO:0051784,GO:0060627,GO:0061160,GO:0061172,GO:0061245,GO:0061246,GO:0061640,GO:0065007,GO:0065008,GO:0070507,GO:0070727,GO:0071944,GO:0071963,GO:0072697,GO:0090337,GO:0097427,GO:0099070,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099738,GO:0110053,GO:0120025,GO:0120038,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902405,GO:1902410,GO:1902486,GO:1902903,GO:1902904,GO:1903047,GO:1904511,GO:1904758,GO:1990151,GO:1990615,GO:1990752,GO:1990778,GO:1990896,GO:2000099,GO:2000100,GO:2000114,GO:2000769,GO:2000771 - 0.00000003666 68.0
DTH2_k127_229004_11 - - - - 0.0000001183 63.0
DTH2_k127_229004_12 Domain of unknown function (DUF3783) - - - 0.00007601 50.0
DTH2_k127_229004_2 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 427.0
DTH2_k127_229004_3 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 335.0
DTH2_k127_229004_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000121 131.0
DTH2_k127_229004_5 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000001398 126.0
DTH2_k127_229004_6 Pfam:KaiC - - - 0.000000000000000000001888 110.0
DTH2_k127_229004_7 - - - - 0.00000000000000001365 97.0
DTH2_k127_229004_8 Transglutaminase/protease-like homologues - - - 0.000000000000008742 91.0
DTH2_k127_229004_9 Protein of unknown function DUF58 - - - 0.0000000006766 71.0
DTH2_k127_2320116_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.359e-225 730.0
DTH2_k127_2320116_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.257e-211 668.0
DTH2_k127_2320116_10 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000005024 99.0
DTH2_k127_2320116_11 Probable zinc-ribbon domain - - - 0.000000000000000003229 85.0
DTH2_k127_2320116_12 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000006186 81.0
DTH2_k127_2320116_13 dipeptidyl-peptidase activity - - - 0.00000001498 66.0
DTH2_k127_2320116_14 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000004038 68.0
DTH2_k127_2320116_15 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.000002747 59.0
DTH2_k127_2320116_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000001993 248.0
DTH2_k127_2320116_3 Protein of unknown function (DUF531) K09725 - - 0.0000000000000000000000000000000000000000000000000003404 190.0
DTH2_k127_2320116_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000001204 186.0
DTH2_k127_2320116_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000003527 179.0
DTH2_k127_2320116_6 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000003396 180.0
DTH2_k127_2320116_7 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000006991 154.0
DTH2_k127_2320116_8 Uncharacterized ArCR, COG1888 K09732 - - 0.000000000000000000000000005331 115.0
DTH2_k127_2320116_9 Uncharacterised protein family (UPF0147) K09721 - - 0.00000000000000000000002374 104.0
DTH2_k127_2353329_0 COG1091 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000000005707 134.0
DTH2_k127_2410196_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 316.0
DTH2_k127_2410196_1 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000003224 231.0
DTH2_k127_2410196_2 hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000004056 84.0
DTH2_k127_2419948_0 RHS Repeat - - - 0.00000000000000000000000001311 126.0
DTH2_k127_2437999_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.579e-281 888.0
DTH2_k127_2437999_1 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 480.0
DTH2_k127_2437999_2 Protein of unknown function (DUF1648) - - - 0.000000000000000000000000000000000000000000000000000000181 201.0
DTH2_k127_2437999_3 Alternative locus ID K15383 - - 0.0000000003584 64.0
DTH2_k127_2437999_4 PhoQ Sensor - - - 0.00000003111 57.0
DTH2_k127_2451425_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 414.0
DTH2_k127_2451425_1 COG2931, RTX toxins and related Ca2 -binding proteins K01729,K20276 - 4.2.2.3 0.0002057 54.0
DTH2_k127_2492134_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 384.0
DTH2_k127_2492134_1 radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 320.0
DTH2_k127_2492134_2 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000709 203.0
DTH2_k127_2492134_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000003227 178.0
DTH2_k127_2492134_4 protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000007991 160.0
DTH2_k127_2492134_5 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.00000000000000000000000000000000000002941 168.0
DTH2_k127_2492134_6 PKD domain - - - 0.00000000008892 77.0
DTH2_k127_2492134_7 Domain of unknown function (DUF4190) - - - 0.00000005475 61.0
DTH2_k127_2492134_8 Glycoside hydrolase family 28 - - - 0.0000001066 67.0
DTH2_k127_2549094_0 RNA-binding - - - 0.0000000000000000000000000005751 115.0
DTH2_k127_2549094_1 - - - - 0.0000001135 56.0
DTH2_k127_2571665_0 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000039 258.0
DTH2_k127_2571665_1 Fibronectin type III domain - - - 0.00000000000000006913 94.0
DTH2_k127_2571665_2 Acetyltransferase (GNAT) domain - - - 0.000000000002053 80.0
DTH2_k127_2621569_0 serine-type peptidase activity K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000003969 244.0
DTH2_k127_2653423_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 378.0
DTH2_k127_2653423_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000002705 141.0
DTH2_k127_2676145_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.882e-263 815.0
DTH2_k127_2676145_1 DNA polymerase type-B family K02319 - 2.7.7.7 1.275e-241 771.0
DTH2_k127_2676145_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000009366 104.0
DTH2_k127_2676145_11 Predicted membrane protein (DUF2085) - - - 0.000000000000693 77.0
DTH2_k127_2676145_12 TPR Domain containing protein - - - 0.000000000004682 76.0
DTH2_k127_2676145_2 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 458.0
DTH2_k127_2676145_3 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 445.0
DTH2_k127_2676145_4 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 381.0
DTH2_k127_2676145_5 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 321.0
DTH2_k127_2676145_6 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000002751 223.0
DTH2_k127_2676145_7 PFAM MOFRL domain protein K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.00000000000000000000000000000000000000000000007789 186.0
DTH2_k127_2676145_8 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000002831 172.0
DTH2_k127_2676145_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000008002 156.0
DTH2_k127_2687350_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 445.0
DTH2_k127_2687350_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000001292 92.0
DTH2_k127_2687350_2 Right handed beta helix region - - - 0.00000000000000678 89.0
DTH2_k127_2687350_3 EF-hand domain K02183 - - 0.0000000008183 68.0
DTH2_k127_2687350_4 - - - - 0.000002841 56.0
DTH2_k127_2878758_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 370.0
DTH2_k127_2878758_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 331.0
DTH2_k127_2994253_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 462.0
DTH2_k127_2994253_1 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000003521 239.0
DTH2_k127_2994253_2 PIN domain - - - 0.0000000000000000000002543 101.0
DTH2_k127_2994253_3 MazG-like family - - - 0.000000000000000000001181 99.0
DTH2_k127_2994253_4 SpoVT / AbrB like domain - - - 0.00001088 51.0
DTH2_k127_3000896_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 5.04e-277 869.0
DTH2_k127_3000896_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 447.0
DTH2_k127_3000896_10 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000007959 88.0
DTH2_k127_3000896_11 - - - - 0.000000000000009948 82.0
DTH2_k127_3000896_12 protein folding K09510 - - 0.000000000874 68.0
DTH2_k127_3000896_13 Belongs to the peptidase S8 family - - - 0.00000005853 67.0
DTH2_k127_3000896_14 RNA-binding protein involved in rRNA processing K07569 - - 0.000001604 55.0
DTH2_k127_3000896_15 Uncharacterized protein K02A2.6-like - - - 0.00002211 54.0
DTH2_k127_3000896_16 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 0.00003284 54.0
DTH2_k127_3000896_17 Chitinase A, N-terminal domain K01183 - 3.2.1.14 0.00007358 57.0
DTH2_k127_3000896_18 SMART Parallel beta-helix repeat - - - 0.0005947 54.0
DTH2_k127_3000896_2 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000121 259.0
DTH2_k127_3000896_3 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000002417 193.0
DTH2_k127_3000896_4 Histidine kinase - - - 0.00000000000000000000000000008675 130.0
DTH2_k127_3000896_5 extracellular matrix structural constituent K02035 - - 0.00000000000000000000000002793 127.0
DTH2_k127_3000896_6 N-6 DNA Methylase K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.0000000000000000000000005036 117.0
DTH2_k127_3000896_7 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000004119 108.0
DTH2_k127_3000896_8 PRC-barrel domain - - - 0.0000000000000000425 83.0
DTH2_k127_3000896_9 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.000000000000007695 81.0
DTH2_k127_3643710_0 PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000003729 188.0
DTH2_k127_3643710_1 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000125 140.0
DTH2_k127_3643710_2 DNA-directed 5'-3' RNA polymerase activity K01387 - 3.4.24.3 0.00000000000005521 82.0
DTH2_k127_3643710_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000024 68.0
DTH2_k127_36773_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000006398 214.0
DTH2_k127_36773_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.000000000000000000000000000000000000000000000009948 196.0
DTH2_k127_36773_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000385 66.0
DTH2_k127_36773_3 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.00008104 57.0
DTH2_k127_36773_4 GxGYxY sequence motif in domain of unknown function N-terminal - - - 0.0001197 57.0
DTH2_k127_36773_5 - - - - 0.0006206 55.0
DTH2_k127_3731213_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 7.426e-306 951.0
DTH2_k127_3731213_1 sarcosine oxidase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 513.0
DTH2_k127_3731213_2 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 366.0
DTH2_k127_3731213_3 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 306.0
DTH2_k127_3731213_4 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.000000000000000000000000000000000000000000000000000000000003351 219.0
DTH2_k127_3731213_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000006767 200.0
DTH2_k127_3731213_6 Thioredoxin K03671 - - 0.000000000000000000000000000000000002986 143.0
DTH2_k127_3731213_7 Snare associated golgi protein - - - 0.00000000000000001065 90.0
DTH2_k127_3731213_8 FR47-like protein - GO:0000902,GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0007154,GO:0007165,GO:0007275,GO:0008080,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009628,GO:0009639,GO:0009640,GO:0009653,GO:0009719,GO:0009723,GO:0009725,GO:0009733,GO:0009734,GO:0009755,GO:0009791,GO:0009826,GO:0009987,GO:0010033,GO:0016043,GO:0016049,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0023052,GO:0032501,GO:0032502,GO:0032870,GO:0032989,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048589,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060560,GO:0065007,GO:0070887,GO:0071310,GO:0071365,GO:0071495,GO:0071704,GO:0071840,GO:1901564 - 0.0000001404 63.0
DTH2_k127_3733826_0 Q COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 501.0
DTH2_k127_3733826_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000005506 213.0
DTH2_k127_3733826_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000001427 188.0
DTH2_k127_3733826_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000001566 128.0
DTH2_k127_3733826_4 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000446 138.0
DTH2_k127_3733826_5 alginic acid biosynthetic process - - - 0.00000000000000000000000000001085 139.0
DTH2_k127_3733826_6 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000001535 117.0
DTH2_k127_3733826_7 endopeptidase inhibitor activity K01406,K03201,K07451,K13613,K19360 - 3.4.24.40 0.0000000000000000176 97.0
DTH2_k127_3733826_8 ABC transporter permease K02004 - - 0.0000000000000001221 95.0
DTH2_k127_3733826_9 PFAM FecR protein K09800,K13735 - - 0.000004659 61.0
DTH2_k127_3760572_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001972 265.0
DTH2_k127_3760572_1 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000006024 166.0
DTH2_k127_3760572_2 Fibronectin type III domain - - - 0.000000000000000000000000000000000000007718 168.0
DTH2_k127_3760572_3 Universal stress protein - - - 0.00000000000000000001045 98.0
DTH2_k127_3760572_4 oxidoreductase activity - - - 0.00000000001931 78.0
DTH2_k127_3760572_5 protein conserved in archaea - - - 0.000000005624 64.0
DTH2_k127_3774683_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001935 259.0
DTH2_k127_3774683_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000006502 138.0
DTH2_k127_3774683_2 Sphaeroforma arctica JP610 - - - 0.000002633 62.0
DTH2_k127_3797675_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 534.0
DTH2_k127_3797675_1 Toprim domain K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 397.0
DTH2_k127_3797675_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 307.0
DTH2_k127_3797675_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000005555 205.0
DTH2_k127_3797675_4 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000004232 159.0
DTH2_k127_3797675_5 - - - - 0.0000000000000000000000000008415 122.0
DTH2_k127_3797675_6 C-terminal domain of CHU protein family - - - 0.000000000007523 79.0
DTH2_k127_3804165_0 TIGRFAM Arsenical-resistance protein K03325 - - 0.0000000000000000000000000000000000000000000000002828 177.0
DTH2_k127_3804165_1 Si ch211-193k19.1 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0031410,GO:0031982,GO:0043226,GO:0043227,GO:0043229,GO:0044424,GO:0044444,GO:0044464,GO:0097708 - 0.000000000000000007587 99.0
DTH2_k127_3813798_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.801e-220 699.0
DTH2_k127_3813798_1 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006931 281.0
DTH2_k127_3813798_10 NUDIX domain K03574 - 3.6.1.55 0.00000000000008637 76.0
DTH2_k127_3813798_11 Class III signal peptide - - - 0.0000003604 61.0
DTH2_k127_3813798_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00006601 55.0
DTH2_k127_3813798_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009103 289.0
DTH2_k127_3813798_3 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000006622 241.0
DTH2_k127_3813798_4 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000244 228.0
DTH2_k127_3813798_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000003114 181.0
DTH2_k127_3813798_6 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000006251 149.0
DTH2_k127_3813798_7 imidazolonepropionase activity K01468 - 3.5.2.7 0.00000000000000000000000000000000002734 140.0
DTH2_k127_3813798_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000001399 137.0
DTH2_k127_3813798_9 archaeal coiled-coil protein - - - 0.00000000000000000000859 104.0
DTH2_k127_3865023_0 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 415.0
DTH2_k127_3865023_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 342.0
DTH2_k127_3865023_2 PFAM GHMP kinase K06982 - 2.7.1.169 0.0000000000000000000000004478 119.0
DTH2_k127_3865023_3 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000006898 74.0
DTH2_k127_3865023_4 Double zinc ribbon - - - 0.00000006974 67.0
DTH2_k127_3865023_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000248 53.0
DTH2_k127_3865023_6 Immunoglobulin like K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.000006381 61.0
DTH2_k127_3865023_7 Bacterial Ig-like domain - - - 0.00001876 59.0
DTH2_k127_3865023_8 - - - - 0.0001086 45.0
DTH2_k127_3915712_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.932e-248 781.0
DTH2_k127_3915712_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 509.0
DTH2_k127_3915712_2 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 384.0
DTH2_k127_3915712_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000004928 234.0
DTH2_k127_3915712_4 Bacterial transcriptional activator domain - - - 0.00000000000000000000000004961 126.0
DTH2_k127_3915712_5 - - - - 0.0000000000000000001863 92.0
DTH2_k127_3915712_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000007107 70.0
DTH2_k127_3915712_7 Glyco_18 K01183 - 3.2.1.14 0.00004456 55.0
DTH2_k127_3955512_0 PFAM TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002078 273.0
DTH2_k127_3955512_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000009136 257.0
DTH2_k127_3955512_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000003131 105.0
DTH2_k127_3955512_11 PFAM PKD domain containing protein - - - 0.0000000000001013 86.0
DTH2_k127_3955512_12 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000001472 59.0
DTH2_k127_3955512_13 DNA-directed RNA polymerase subunit beta' - - - 0.0002874 55.0
DTH2_k127_3955512_2 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003616 250.0
DTH2_k127_3955512_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000002154 267.0
DTH2_k127_3955512_4 Met-10+ like-protein K07055 - 2.5.1.114 0.000000000000000000000000000000000000000000000000002241 197.0
DTH2_k127_3955512_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000000000001644 167.0
DTH2_k127_3955512_6 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000002232 184.0
DTH2_k127_3955512_7 Cation transport protein K03498 - - 0.0000000000000000000000000000000000000000003936 176.0
DTH2_k127_3955512_8 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000002417 115.0
DTH2_k127_3955512_9 hmm pf03415 K08587 - 3.4.22.8 0.0000000000000000000008606 113.0
DTH2_k127_4053213_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.714e-273 865.0
DTH2_k127_4053213_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.642e-256 807.0
DTH2_k127_4053213_10 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000000000000001005 214.0
DTH2_k127_4053213_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000001419 211.0
DTH2_k127_4053213_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000122 173.0
DTH2_k127_4053213_13 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000001525 184.0
DTH2_k127_4053213_14 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000001793 183.0
DTH2_k127_4053213_15 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000001911 165.0
DTH2_k127_4053213_16 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000000000000000000006925 154.0
DTH2_k127_4053213_17 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002246 147.0
DTH2_k127_4053213_18 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000002047 136.0
DTH2_k127_4053213_19 adenyl ribonucleotide binding - - - 0.00000000000000000000000000000004524 133.0
DTH2_k127_4053213_2 PFAM Type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 576.0
DTH2_k127_4053213_20 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000007701 128.0
DTH2_k127_4053213_21 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000005284 124.0
DTH2_k127_4053213_22 AraC-like ligand binding domain - - - 0.0000000000000000000000000001205 122.0
DTH2_k127_4053213_23 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000006005 123.0
DTH2_k127_4053213_24 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000001504 129.0
DTH2_k127_4053213_25 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000455 116.0
DTH2_k127_4053213_26 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000004653 110.0
DTH2_k127_4053213_27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000009713 101.0
DTH2_k127_4053213_28 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000009216 104.0
DTH2_k127_4053213_29 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000008784 93.0
DTH2_k127_4053213_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 563.0
DTH2_k127_4053213_30 - - - - 0.00000000000000000123 94.0
DTH2_k127_4053213_31 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000000000001342 98.0
DTH2_k127_4053213_32 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000003821 83.0
DTH2_k127_4053213_33 transcriptional - - - 0.000000000000000161 89.0
DTH2_k127_4053213_34 chitinase K01183 - 3.2.1.14 0.000000002377 72.0
DTH2_k127_4053213_35 Archaebacterial flagellin K07330 - - 0.000000002972 65.0
DTH2_k127_4053213_36 PKD domain - - - 0.000000003043 68.0
DTH2_k127_4053213_37 Flagella accessory protein C (FlaC) K07327,K07328 - - 0.000000003186 68.0
DTH2_k127_4053213_38 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.000000003375 70.0
DTH2_k127_4053213_39 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000001536 68.0
DTH2_k127_4053213_4 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 491.0
DTH2_k127_4053213_40 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000004847 63.0
DTH2_k127_4053213_41 Phosphoserine phosphatase - - - 0.000000099 62.0
DTH2_k127_4053213_42 Domain of unknown function DUF11 - - - 0.0000002565 65.0
DTH2_k127_4053213_43 methyltransferase (Contains TPR repeat) - - - 0.000001164 61.0
DTH2_k127_4053213_44 Belongs to the 'phage' integrase family - - - 0.000003059 53.0
DTH2_k127_4053213_45 Protein of unknown function (DUF3198) - - - 0.000004655 54.0
DTH2_k127_4053213_46 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000007593 56.0
DTH2_k127_4053213_47 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000245 55.0
DTH2_k127_4053213_5 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 402.0
DTH2_k127_4053213_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 313.0
DTH2_k127_4053213_7 RNA cap guanine-N2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009394 246.0
DTH2_k127_4053213_8 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000006624 234.0
DTH2_k127_4053213_9 PFAM Type II secretion system F domain K07333 - - 0.00000000000000000000000000000000000000000000000000000000000001724 235.0
DTH2_k127_4080185_0 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 1.33e-292 923.0
DTH2_k127_4080185_1 Peptidase family S51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003035 267.0
DTH2_k127_4080185_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K03885,K17870 - 1.6.3.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001664 265.0
DTH2_k127_4080185_3 tRNA synthetases class II (A) K01872 - 6.1.1.7 0.000000000004438 71.0
DTH2_k127_4096997_0 Esterase PHB depolymerase - - - 0.0002702 55.0
DTH2_k127_4096997_1 guanyl-nucleotide exchange factor activity K15923 - 3.2.1.51 0.0003556 55.0
DTH2_k127_4185087_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 553.0
DTH2_k127_4185087_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 381.0
DTH2_k127_4185087_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000004296 225.0
DTH2_k127_4185087_3 RIO-like kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000166 181.0
DTH2_k127_4185087_4 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000001804 116.0
DTH2_k127_4185087_5 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.0000000006756 61.0
DTH2_k127_4185945_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000001903 76.0
DTH2_k127_4222582_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
DTH2_k127_4222582_1 Integral membrane protein DUF92 - - - 0.000000000000000000000000000003964 129.0
DTH2_k127_4222582_2 snRNP Sm proteins K04796 - - 0.00000000000000003088 83.0
DTH2_k127_4222582_3 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000002804 77.0
DTH2_k127_4222582_4 Domain of unknown function (DUF1992) - - - 0.0002103 45.0
DTH2_k127_4231042_0 PFAM Band 7 protein - - - 2.3e-267 838.0
DTH2_k127_4231042_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 5.986e-219 692.0
DTH2_k127_4231042_10 PFAM amidohydrolase K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 324.0
DTH2_k127_4231042_11 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 304.0
DTH2_k127_4231042_12 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 304.0
DTH2_k127_4231042_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 299.0
DTH2_k127_4231042_14 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 288.0
DTH2_k127_4231042_15 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001581 264.0
DTH2_k127_4231042_16 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000007004 262.0
DTH2_k127_4231042_17 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000004343 251.0
DTH2_k127_4231042_18 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000004887 237.0
DTH2_k127_4231042_19 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000001027 254.0
DTH2_k127_4231042_2 CobW/HypB/UreG, nucleotide-binding domain - - - 1.247e-196 621.0
DTH2_k127_4231042_20 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001846 206.0
DTH2_k127_4231042_21 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000003701 194.0
DTH2_k127_4231042_22 ATP binding protein K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000004294 172.0
DTH2_k127_4231042_24 PFAM Cupin domain - - - 0.00000000000000000000000000000000000000002966 154.0
DTH2_k127_4231042_25 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000003361 164.0
DTH2_k127_4231042_26 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000006164 163.0
DTH2_k127_4231042_27 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000002932 139.0
DTH2_k127_4231042_28 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000001798 103.0
DTH2_k127_4231042_29 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000004076 102.0
DTH2_k127_4231042_3 Asparaginase K01424 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 613.0
DTH2_k127_4231042_30 Parallel beta-helix repeats - - - 0.0000000000000001066 92.0
DTH2_k127_4231042_31 RHS Repeat - - - 0.00000000000000071 93.0
DTH2_k127_4231042_32 Pfam:KaiC K08482 - - 0.000000000000002098 86.0
DTH2_k127_4231042_33 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.0000000000000156 84.0
DTH2_k127_4231042_34 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000002504 81.0
DTH2_k127_4231042_35 RNA binding K07581 - - 0.00000000000004117 79.0
DTH2_k127_4231042_36 Transcription factor zinc-finger K09981 - - 0.0000000000003546 75.0
DTH2_k127_4231042_37 Methyltransferase domain - - - 0.0000000004395 69.0
DTH2_k127_4231042_38 protein conserved in archaea - - - 0.0000000006843 67.0
DTH2_k127_4231042_39 FG-GAP repeat - - - 0.000000001015 73.0
DTH2_k127_4231042_4 aminopeptidase K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 488.0
DTH2_k127_4231042_40 protein conserved in archaea - - - 0.000000005351 64.0
DTH2_k127_4231042_41 collagen metabolic process K05994,K08677,K14645 - 3.4.11.10 0.000000009155 70.0
DTH2_k127_4231042_43 Right handed beta helix region - - - 0.00000003251 68.0
DTH2_k127_4231042_44 self proteolysis - - - 0.0000001063 63.0
DTH2_k127_4231042_45 Protein tyrosine kinase K12132 - 2.7.11.1 0.000003109 59.0
DTH2_k127_4231042_46 metallopeptidase activity K01387 - 3.4.24.3 0.000009399 59.0
DTH2_k127_4231042_47 lipoate-protein ligase A K03800 - 6.3.1.20 0.00004552 50.0
DTH2_k127_4231042_49 Domain in cystathionine beta-synthase and other proteins. - - - 0.0006313 48.0
DTH2_k127_4231042_5 binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 470.0
DTH2_k127_4231042_50 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0008226 51.0
DTH2_k127_4231042_6 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 383.0
DTH2_k127_4231042_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 372.0
DTH2_k127_4231042_8 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 359.0
DTH2_k127_4231042_9 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 345.0
DTH2_k127_424425_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.402e-299 930.0
DTH2_k127_424425_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 463.0
DTH2_k127_424425_10 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000002601 149.0
DTH2_k127_424425_11 Male sterility protein - - - 0.0000000000000000000000000000000711 137.0
DTH2_k127_424425_12 - - - - 0.00000000000000000000002254 108.0
DTH2_k127_424425_13 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000005936 100.0
DTH2_k127_424425_14 domain, Protein - - - 0.00000000000000000686 100.0
DTH2_k127_424425_15 domain protein - - - 0.00000000000000002096 94.0
DTH2_k127_424425_16 Response regulator receiver domain - - - 0.00000000000000004328 85.0
DTH2_k127_424425_17 Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.00000001886 69.0
DTH2_k127_424425_18 Ion channel K10716 - - 0.0000003253 63.0
DTH2_k127_424425_19 but it may be involved in stabilization of the trimeric complex - - - 0.000001117 52.0
DTH2_k127_424425_2 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 427.0
DTH2_k127_424425_20 pyrroloquinoline quinone binding - - - 0.000001722 63.0
DTH2_k127_424425_21 Universal stress protein - - - 0.000007465 55.0
DTH2_k127_424425_22 Belongs to the UPF0248 family K09715 - - 0.00004968 51.0
DTH2_k127_424425_23 FHA domain - - - 0.0002646 50.0
DTH2_k127_424425_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 374.0
DTH2_k127_424425_4 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 368.0
DTH2_k127_424425_5 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000003124 253.0
DTH2_k127_424425_6 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000002819 236.0
DTH2_k127_424425_7 metallocarboxypeptidase activity K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000005075 189.0
DTH2_k127_424425_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000105 168.0
DTH2_k127_424425_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000477 171.0
DTH2_k127_4283447_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1020.0
DTH2_k127_4283447_1 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 565.0
DTH2_k127_4283447_10 Na H ion antiporter subunit K05569 - - 0.00000000000000000000000000000000000000000003222 168.0
DTH2_k127_4283447_11 binding domain protein - - - 0.000000000000000000000000000000000000000311 155.0
DTH2_k127_4283447_12 PFAM Na H antiporter MnhB subunit-related protein K05566 - - 0.000000000000000000000000000000003941 133.0
DTH2_k127_4283447_13 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.00000000000000000000000000000004364 133.0
DTH2_k127_4283447_14 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.00000000000000000000000000001646 126.0
DTH2_k127_4283447_15 PFAM NADH-ubiquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000002653 118.0
DTH2_k127_4283447_16 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000000000000008274 89.0
DTH2_k127_4283447_17 Domain of unknown function (DUF4040) - - - 0.000000000000000005225 90.0
DTH2_k127_4283447_18 Membrane bound hydrogenase - - - 0.0000000000003626 76.0
DTH2_k127_4283447_19 protein conserved in archaea K09723 - - 0.0000684 53.0
DTH2_k127_4283447_2 NADH-Ubiquinone plastoquinone (complex I) K05568,K14115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 522.0
DTH2_k127_4283447_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K18016 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 452.0
DTH2_k127_4283447_4 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 310.0
DTH2_k127_4283447_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 288.0
DTH2_k127_4283447_6 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008831 270.0
DTH2_k127_4283447_7 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
DTH2_k127_4283447_8 Belongs to the complex I 20 kDa subunit family K18023 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000001686 212.0
DTH2_k127_4283447_9 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000005735 175.0
DTH2_k127_4316027_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 587.0
DTH2_k127_4316027_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 431.0
DTH2_k127_4316027_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000001286 156.0
DTH2_k127_4316027_11 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000157 148.0
DTH2_k127_4316027_12 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000001503 147.0
DTH2_k127_4316027_13 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000003535 135.0
DTH2_k127_4316027_14 Kelch motif - - - 0.00000000000000003533 97.0
DTH2_k127_4316027_15 - - - - 0.0000000001234 66.0
DTH2_k127_4316027_16 COG0456 Acetyltransferases K03789 - 2.3.1.128 0.0000000001333 68.0
DTH2_k127_4316027_17 biotin apo-protein ligase-related - - - 0.0000000324 64.0
DTH2_k127_4316027_18 Putative zinc- or iron-chelating domain K06940 - - 0.00000006874 60.0
DTH2_k127_4316027_19 - - - - 0.0000006973 59.0
DTH2_k127_4316027_2 GatB/GatE catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 422.0
DTH2_k127_4316027_20 Periplasmic Protein - - - 0.0002394 53.0
DTH2_k127_4316027_21 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0006653 53.0
DTH2_k127_4316027_3 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 404.0
DTH2_k127_4316027_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 296.0
DTH2_k127_4316027_5 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000059 267.0
DTH2_k127_4316027_6 PhoU domain - - - 0.00000000000000000000000000000000000000000000000005856 197.0
DTH2_k127_4316027_7 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000001367 188.0
DTH2_k127_4316027_8 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000001145 180.0
DTH2_k127_4316027_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000002948 163.0
DTH2_k127_435171_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 469.0
DTH2_k127_435171_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 451.0
DTH2_k127_435171_10 Peptidase family C25 - - - 0.00000000000000000000003667 117.0
DTH2_k127_435171_11 Belongs to the snRNP Sm proteins family K04796 - - 0.0000000000000000000008278 96.0
DTH2_k127_435171_12 - - - - 0.000000000000000005202 97.0
DTH2_k127_435171_13 binds to the 23S rRNA K02922 - - 0.000000000000000009543 84.0
DTH2_k127_435171_14 von Willebrand factor type A - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000002028 87.0
DTH2_k127_435171_15 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.000000000001553 77.0
DTH2_k127_435171_16 von Willebrand factor, type A K03404,K03405 - 6.6.1.1 0.000000002313 70.0
DTH2_k127_435171_17 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000002312 68.0
DTH2_k127_435171_18 TM2 domain - - - 0.000005539 52.0
DTH2_k127_435171_19 MobA-like NTP transferase domain - - - 0.00002631 56.0
DTH2_k127_435171_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 346.0
DTH2_k127_435171_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 332.0
DTH2_k127_435171_4 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000001941 214.0
DTH2_k127_435171_5 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000001893 203.0
DTH2_k127_435171_6 Phosphoheptose isomerase K03271 - 5.3.1.28 0.0000000000000000000000000000000000000001428 157.0
DTH2_k127_435171_7 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000009804 122.0
DTH2_k127_435171_8 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000003886 125.0
DTH2_k127_435171_9 - - - - 0.0000000000000000000000007147 119.0
DTH2_k127_435279_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 475.0
DTH2_k127_435279_1 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000007432 208.0
DTH2_k127_435279_2 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000001769 181.0
DTH2_k127_435279_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000001276 76.0
DTH2_k127_435279_4 Protein of unknown function (DUF401) K09133 - - 0.000000000002905 78.0
DTH2_k127_435279_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000001782 68.0
DTH2_k127_4356627_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 6.205e-232 732.0
DTH2_k127_4356627_1 citrate CoA-transferase activity K01643 - 2.8.3.10 2.022e-225 709.0
DTH2_k127_4356627_10 Extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000009058 235.0
DTH2_k127_4356627_11 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000006229 216.0
DTH2_k127_4356627_12 metal-dependent phosphohydrolase, HD sub domain K03698,K12070 - - 0.000000000000000000000000000000000000000000000000000000000008312 212.0
DTH2_k127_4356627_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000002825 192.0
DTH2_k127_4356627_14 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000004557 193.0
DTH2_k127_4356627_15 PAS domain - - - 0.0000000000000000000000000000000000000000000000008469 196.0
DTH2_k127_4356627_16 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.0000000000000000000000000000000000000000000000188 198.0
DTH2_k127_4356627_17 sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000008036 175.0
DTH2_k127_4356627_18 manganese ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000002223 162.0
DTH2_k127_4356627_19 cell wall organization - - - 0.00000000000000000000000000748 130.0
DTH2_k127_4356627_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 2.08e-209 663.0
DTH2_k127_4356627_20 - K01992,K19341 - - 0.00000000000000006498 95.0
DTH2_k127_4356627_21 ABC-2 family transporter protein K01992 - - 0.0000000000002572 79.0
DTH2_k127_4356627_22 Glucose / Sorbosone dehydrogenase - - - 0.00000000004487 78.0
DTH2_k127_4356627_23 Belongs to the peptidase S1B family - - - 0.00000005728 67.0
DTH2_k127_4356627_24 COG2002 Regulators of stationary sporulation gene expression - - - 0.0000009008 53.0
DTH2_k127_4356627_25 AcrB/AcrD/AcrF family - - - 0.0001514 48.0
DTH2_k127_4356627_26 domain protein K14274 - - 0.0002232 55.0
DTH2_k127_4356627_3 3-isopropylmalate dehydrogenase activity K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 587.0
DTH2_k127_4356627_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 496.0
DTH2_k127_4356627_5 Aconitase family (aconitate hydratase) K01703,K01705,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35,4.2.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 461.0
DTH2_k127_4356627_6 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 393.0
DTH2_k127_4356627_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 299.0
DTH2_k127_4356627_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004443 271.0
DTH2_k127_4356627_9 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002965 263.0
DTH2_k127_4426791_0 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 423.0
DTH2_k127_4426791_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 293.0
DTH2_k127_4426791_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000002509 223.0
DTH2_k127_4426791_3 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000001936 187.0
DTH2_k127_4426791_4 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000009801 106.0
DTH2_k127_4426791_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000003524 73.0
DTH2_k127_4426791_7 Universal stress protein family - - - 0.00000001389 62.0
DTH2_k127_4522319_0 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 384.0
DTH2_k127_4522319_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 336.0
DTH2_k127_4522319_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000001583 243.0
DTH2_k127_4522319_3 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000005701 170.0
DTH2_k127_4522319_4 COG3209 Rhs family protein - - - 0.000000000000000000000000000000008824 149.0
DTH2_k127_4522319_5 MacB-like periplasmic core domain K09808 - - 0.00000618 58.0
DTH2_k127_4522319_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00001183 57.0
DTH2_k127_4580998_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000009382 257.0
DTH2_k127_4580998_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000001792 72.0
DTH2_k127_4584110_0 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 497.0
DTH2_k127_4584110_1 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 315.0
DTH2_k127_4584110_2 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000000000000000000000000000000000009216 200.0
DTH2_k127_4584110_3 Right handed beta helix region - - - 0.000000000000000000000000003876 125.0
DTH2_k127_4584110_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000008694 110.0
DTH2_k127_4584110_5 EamA-like transporter family K08978 - - 0.0000000000000000000001473 102.0
DTH2_k127_4584110_6 Belongs to the UPF0201 family K09736 - - 0.00000000000000004692 85.0
DTH2_k127_4584110_7 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000001418 72.0
DTH2_k127_4584110_8 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000006631 68.0
DTH2_k127_4584110_9 Transcriptional regulator - - - 0.00000001355 68.0
DTH2_k127_4647802_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 6.014e-263 819.0
DTH2_k127_4647802_1 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 546.0
DTH2_k127_4647802_2 FeoA K03709 - - 0.000000000000000000000000000000000000000000000000000000000000001647 225.0
DTH2_k127_4647802_3 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000001581 183.0
DTH2_k127_4648823_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 442.0
DTH2_k127_4648823_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 312.0
DTH2_k127_4648823_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005565 280.0
DTH2_k127_4648823_3 Alcohol dehydrogenase, class IV K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000156 194.0
DTH2_k127_4648823_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000001421 154.0
DTH2_k127_4648823_5 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000009955 143.0
DTH2_k127_4648823_6 cellulase activity - - - 0.000000002165 73.0
DTH2_k127_4648823_7 PUA domain K07557 - 2.6.1.97 0.0000008829 59.0
DTH2_k127_4732078_0 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000001085 243.0
DTH2_k127_4732078_1 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000001631 207.0
DTH2_k127_4732078_10 TOPRIM - - - 0.000000000006596 71.0
DTH2_k127_4732078_11 Transcriptional regulator, ArsR family - - - 0.00000000001069 74.0
DTH2_k127_4732078_12 Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment - GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:1901678 - 0.00000000003061 69.0
DTH2_k127_4732078_2 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000008203 178.0
DTH2_k127_4732078_3 PFAM Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000000000000115 177.0
DTH2_k127_4732078_4 Pfam:KaiC - - - 0.000000000000000000000000000000000000000009632 163.0
DTH2_k127_4732078_5 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.000000000000000000000000000000000000003099 166.0
DTH2_k127_4732078_6 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000007567 162.0
DTH2_k127_4732078_7 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000007623 149.0
DTH2_k127_4732078_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000002263 118.0
DTH2_k127_4732078_9 S-layer protein - - - 0.000000000000000000008529 108.0
DTH2_k127_4745142_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 474.0
DTH2_k127_4745142_1 transport system permease K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 348.0
DTH2_k127_4745142_2 ABC-type thiamine transport system, periplasmic component K02064 - - 0.000000000000000000000000000000000000000000000000000000000000000000381 242.0
DTH2_k127_4745142_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000009742 253.0
DTH2_k127_4745142_4 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000001665 217.0
DTH2_k127_4745142_5 Thiamine-phosphate synthase K22206 - - 0.00000000000000000000000000000000001069 147.0
DTH2_k127_4745142_6 - - - - 0.0000000000000000004184 102.0
DTH2_k127_4745142_7 cyclic nucleotide binding K10914 - - 0.0000000000002957 74.0
DTH2_k127_4745142_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000002398 73.0
DTH2_k127_4745142_9 Acetyltransferase (GNAT) domain - - - 0.00000005114 65.0
DTH2_k127_4781101_0 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.00000000000000000000000000000000000000664 158.0
DTH2_k127_4781101_1 EamA-like transporter family - - - 0.00004774 55.0
DTH2_k127_5003810_0 Carboxypeptidase regulatory-like domain K20276 - - 0.0005584 53.0
DTH2_k127_5062922_0 serine-type endopeptidase inhibitor activity K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 319.0
DTH2_k127_5062922_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004097 275.0
DTH2_k127_5062922_2 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000005193 171.0
DTH2_k127_5062922_3 C-terminal domain of CHU protein family - - - 0.00000000000000004602 90.0
DTH2_k127_5062922_4 anaphase-promoting complex binding - - - 0.0000000003066 74.0
DTH2_k127_5093010_0 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 385.0
DTH2_k127_5093010_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000006078 145.0
DTH2_k127_5093010_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000001999 128.0
DTH2_k127_5093010_3 S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 K15450 - 2.1.1.282 0.00000000000000000000000004347 118.0
DTH2_k127_5182273_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001022 283.0
DTH2_k127_5182273_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000002408 226.0
DTH2_k127_5182273_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000003214 113.0
DTH2_k127_5182273_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000004703 98.0
DTH2_k127_520690_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 529.0
DTH2_k127_520690_1 PUA domain containing protein K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 470.0
DTH2_k127_520690_10 PFAM NHL repeat containing protein - - - 0.00000000000000000000000008529 126.0
DTH2_k127_520690_11 Belongs to the peptidase S8 family K20276 - - 0.000000000000000002216 102.0
DTH2_k127_520690_12 Fcf1 K07158 - - 0.0000000000000002659 85.0
DTH2_k127_520690_13 COG2931, RTX toxins and related Ca2 -binding proteins K01729,K20276 - 4.2.2.3 0.000001249 63.0
DTH2_k127_520690_2 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 441.0
DTH2_k127_520690_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 391.0
DTH2_k127_520690_4 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000006538 201.0
DTH2_k127_520690_5 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000004271 181.0
DTH2_k127_520690_6 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000007372 160.0
DTH2_k127_520690_7 ribosomal protein K02956 - - 0.00000000000000000000000000000000000000006407 156.0
DTH2_k127_520690_8 Histidine kinase-like ATPases K12132 - 2.7.11.1 0.00000000000000000000000000000000001744 155.0
DTH2_k127_520690_9 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.0000000000000000000000000000000002065 142.0
DTH2_k127_5213819_0 Carboxypeptidase regulatory-like domain - - - 0.000012 59.0
DTH2_k127_5273935_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000375 262.0
DTH2_k127_5273935_1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000002542 238.0
DTH2_k127_5273935_10 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000002741 71.0
DTH2_k127_5273935_11 - - - - 0.0004455 46.0
DTH2_k127_5273935_2 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000003801 228.0
DTH2_k127_5273935_3 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001535 193.0
DTH2_k127_5273935_4 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000487 163.0
DTH2_k127_5273935_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000000002957 153.0
DTH2_k127_5273935_6 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000003594 119.0
DTH2_k127_5273935_7 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000002661 106.0
DTH2_k127_5273935_8 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000000000000004777 85.0
DTH2_k127_5273935_9 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000004896 78.0
DTH2_k127_5282651_0 Putative Ig domain - - - 0.000000008311 69.0
DTH2_k127_528600_0 Inter-alpha-trypsin inhibitor heavy chain - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.0000000000000000000000000000000000000000000000001319 193.0
DTH2_k127_528600_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0001307 48.0
DTH2_k127_5288090_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.581e-283 883.0
DTH2_k127_5288090_1 transferase activity, transferring acyl groups K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 442.0
DTH2_k127_5288090_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 441.0
DTH2_k127_5288090_3 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000001203 232.0
DTH2_k127_5288090_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000001323 163.0
DTH2_k127_5288090_5 - - - - 0.0000141 58.0
DTH2_k127_5312576_0 Creatinase/Prolidase N-terminal domain K01262,K02027 - 3.4.11.9 2.672e-210 671.0
DTH2_k127_5312576_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 411.0
DTH2_k127_5312576_10 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000000003393 158.0
DTH2_k127_5312576_11 Uncharacterized protein family UPF0029 - - - 0.000000000000000000000000000000000007241 143.0
DTH2_k127_5312576_12 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000008581 83.0
DTH2_k127_5312576_13 Circadian clock protein KaiC K06945 - - 0.0000000000203 77.0
DTH2_k127_5312576_14 - - - - 0.00000006968 57.0
DTH2_k127_5312576_15 - - - - 0.000002778 56.0
DTH2_k127_5312576_17 - - - - 0.000007489 54.0
DTH2_k127_5312576_18 Protein of unknown function (DUF835) - - - 0.000127 52.0
DTH2_k127_5312576_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 352.0
DTH2_k127_5312576_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 325.0
DTH2_k127_5312576_4 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 320.0
DTH2_k127_5312576_5 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 326.0
DTH2_k127_5312576_6 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 297.0
DTH2_k127_5312576_7 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000007261 244.0
DTH2_k127_5312576_8 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000001156 218.0
DTH2_k127_5312576_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000006924 195.0
DTH2_k127_5344611_0 OPT oligopeptide transporter protein - - - 0.00001046 58.0
DTH2_k127_5344611_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00002493 50.0
DTH2_k127_5348556_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 668.0
DTH2_k127_5348556_1 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 387.0
DTH2_k127_5348556_10 Protein of unknown function DUF58 - - - 0.00000000000000000006328 104.0
DTH2_k127_5348556_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000001541 92.0
DTH2_k127_5348556_12 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000005597 87.0
DTH2_k127_5348556_13 Belongs to the ompA family K20276 - - 0.0000000004122 73.0
DTH2_k127_5348556_14 Ribbon-helix-helix protein, copG family K07722 - - 0.00006021 50.0
DTH2_k127_5348556_15 N-Acetylmuramoyl-L-alanine amidase - - - 0.0000917 51.0
DTH2_k127_5348556_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 336.0
DTH2_k127_5348556_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 300.0
DTH2_k127_5348556_4 BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000000259 241.0
DTH2_k127_5348556_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000000006885 244.0
DTH2_k127_5348556_6 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000005206 232.0
DTH2_k127_5348556_7 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000001158 192.0
DTH2_k127_5348556_8 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000000000000000000000001586 177.0
DTH2_k127_5348556_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000001499 161.0
DTH2_k127_5620154_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000005809 157.0
DTH2_k127_5620154_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000004778 65.0
DTH2_k127_5620154_2 Nuclear matrix constituent protein 1-like - GO:0000229,GO:0000785,GO:0000789,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005652,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0005911,GO:0006996,GO:0006997,GO:0008150,GO:0009506,GO:0009987,GO:0012505,GO:0016043,GO:0030054,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032535,GO:0034399,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0055044,GO:0065007,GO:0065008,GO:0070013,GO:0071840,GO:0090066,GO:0097298 - 0.0005462 53.0
DTH2_k127_562754_0 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000000000000001795 108.0
DTH2_k127_562754_1 Subtilase family - - - 0.0000000000000002177 95.0
DTH2_k127_562754_2 Fibronectin type III domain - - - 0.0000001162 66.0
DTH2_k127_5746949_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.726e-218 713.0
DTH2_k127_5746949_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007209 278.0
DTH2_k127_5746949_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003939 254.0
DTH2_k127_5746949_3 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000004124 213.0
DTH2_k127_5746949_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000109 179.0
DTH2_k127_5746949_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000001923 128.0
DTH2_k127_5746949_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000002172 111.0
DTH2_k127_5746949_7 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000005388 74.0
DTH2_k127_5746949_8 SMART Parallel beta-helix repeat - - - 0.00000005779 67.0
DTH2_k127_5806946_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 1.414e-241 760.0
DTH2_k127_5806946_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 2.268e-194 625.0
DTH2_k127_5806946_10 KaiC - - - 0.0000001039 62.0
DTH2_k127_5806946_11 N-Acetylmuramoyl-L-alanine amidase - - - 0.0003132 49.0
DTH2_k127_5806946_2 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 561.0
DTH2_k127_5806946_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 501.0
DTH2_k127_5806946_4 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000001505 244.0
DTH2_k127_5806946_5 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000002436 190.0
DTH2_k127_5806946_6 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000005491 194.0
DTH2_k127_5806946_7 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000002126 104.0
DTH2_k127_5806946_8 domain protein - - - 0.000000000000000000001324 112.0
DTH2_k127_5806946_9 Right handed beta helix region - - - 0.000000000008382 80.0
DTH2_k127_5819266_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 451.0
DTH2_k127_5819266_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 329.0
DTH2_k127_5819266_10 PFAM Glycosyl hydrolases family 38 C-terminal domain - - - 0.0007328 53.0
DTH2_k127_5819266_2 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000004299 173.0
DTH2_k127_5819266_3 Methyltransferase type 11 - - - 0.00000000000000000000000001502 118.0
DTH2_k127_5819266_4 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000001614 114.0
DTH2_k127_5819266_5 Integral membrane protein DUF106 - - - 0.0000000000000000004039 98.0
DTH2_k127_5819266_6 PFAM membrane-bound metal-dependent hydrolase K07038 - - 0.00000000000000001185 87.0
DTH2_k127_5819266_7 cell wall organization - - - 0.00000004712 67.0
DTH2_k127_5819266_8 Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - 0.000001103 62.0
DTH2_k127_5819266_9 Periplasmic copper-binding protein (NosD) - - - 0.0004794 53.0
DTH2_k127_5852480_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 5.914e-231 733.0
DTH2_k127_5852480_1 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 364.0
DTH2_k127_5852480_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000001071 214.0
DTH2_k127_5852480_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000001607 219.0
DTH2_k127_5852480_4 PFAM Transketolase central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000009989 167.0
DTH2_k127_5852480_5 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity) K01170 - 4.6.1.16 0.000000000000000000000000000001074 133.0
DTH2_k127_5852480_6 beta-lactamase domain protein - - - 0.000000000000000000000000000005096 127.0
DTH2_k127_5852480_7 PFAM glutaredoxin - - - 0.0000000000000000000000000007615 115.0
DTH2_k127_5852480_8 Carbohydrate binding domain (family 25) - - - 0.0000004501 64.0
DTH2_k127_5892047_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000009028 60.0
DTH2_k127_6036959_0 Thrombospondin type 3 repeat - - - 0.000000001618 70.0
DTH2_k127_6165283_0 rhs family - - - 0.0000001143 64.0
DTH2_k127_6176386_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 1.384e-216 704.0
DTH2_k127_6242647_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.013e-231 748.0
DTH2_k127_6242647_1 Thymidylate synthase complementing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 300.0
DTH2_k127_6242647_10 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.0002123 47.0
DTH2_k127_6242647_11 rhs family - - - 0.000576 53.0
DTH2_k127_6242647_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000177 265.0
DTH2_k127_6242647_3 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000002116 173.0
DTH2_k127_6242647_4 PBP superfamily domain K02040 GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - 0.00000000000000000000000000000000001709 148.0
DTH2_k127_6242647_5 glucose-6-phosphate isomerase activity K01810 - 5.3.1.9 0.0000000000000000000000003026 119.0
DTH2_k127_6242647_6 domain, Protein - - - 0.0000000000000000000000226 118.0
DTH2_k127_6242647_7 Cellulase N-terminal ig-like domain K20276 - - 0.000000004088 70.0
DTH2_k127_6242647_8 Peptidase family C25 - - - 0.000001587 63.0
DTH2_k127_6242647_9 protein conserved in archaea K07013 - - 0.00002777 58.0
DTH2_k127_6354447_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.116e-221 699.0
DTH2_k127_6354447_1 Required for chromosome condensation and partitioning K03529 - - 4.278e-200 667.0
DTH2_k127_6354447_10 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000001418 162.0
DTH2_k127_6354447_11 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000003182 147.0
DTH2_k127_6354447_12 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000196 145.0
DTH2_k127_6354447_13 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000003539 115.0
DTH2_k127_6354447_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.000000000000000000000002183 117.0
DTH2_k127_6354447_15 membrane transporter protein K07090 - - 0.00000000000000000003618 100.0
DTH2_k127_6354447_16 PKD domain containing protein K01179,K07004,K13277,K20276,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 0.000000000000000000269 104.0
DTH2_k127_6354447_17 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.000000000000000005611 88.0
DTH2_k127_6354447_18 2TM domain - - - 0.00000000000000003362 84.0
DTH2_k127_6354447_2 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 392.0
DTH2_k127_6354447_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 354.0
DTH2_k127_6354447_4 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002135 250.0
DTH2_k127_6354447_5 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000004394 222.0
DTH2_k127_6354447_6 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000004841 184.0
DTH2_k127_6354447_7 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000009055 185.0
DTH2_k127_6354447_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000001211 160.0
DTH2_k127_6354447_9 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000000004868 151.0
DTH2_k127_6457201_0 to MEROPS metallopeptidase family M28E K05994 - 3.4.11.10 0.00000000000000000000009998 114.0
DTH2_k127_6457201_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000007736 75.0
DTH2_k127_6467257_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 414.0
DTH2_k127_6467257_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001188 250.0
DTH2_k127_6467257_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000001477 83.0
DTH2_k127_6467257_3 Possibly the antitoxin component of a - - - 0.0001924 46.0
DTH2_k127_6534070_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1113.0
DTH2_k127_6534070_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1024.0
DTH2_k127_6534070_10 Q COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000002992 208.0
DTH2_k127_6534070_11 4fe-4S ferredoxin, iron-sulfur binding domain protein K00441,K00528,K03522,K03616 - 1.12.98.1,1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000001974 168.0
DTH2_k127_6534070_12 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000002103 138.0
DTH2_k127_6534070_13 - - - - 0.00000000000000000000000000001643 124.0
DTH2_k127_6534070_14 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000002393 122.0
DTH2_k127_6534070_15 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000832 97.0
DTH2_k127_6534070_16 PKD domain - - - 0.0000000000000000001693 105.0
DTH2_k127_6534070_17 Thermolysin metallopeptidase, catalytic domain K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.0000000000000001003 96.0
DTH2_k127_6534070_18 S-layer protein - - - 0.0000000000000004941 93.0
DTH2_k127_6534070_19 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000008728 84.0
DTH2_k127_6534070_2 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.053e-264 824.0
DTH2_k127_6534070_20 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000001173 85.0
DTH2_k127_6534070_21 conserved repeat domain protein - - - 0.000000000000005661 90.0
DTH2_k127_6534070_22 Predicted membrane protein (DUF2085) - - - 0.00000000000005617 77.0
DTH2_k127_6534070_23 Belongs to the peptidase S8 family K20276 - - 0.0000000001506 76.0
DTH2_k127_6534070_24 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000006284 61.0
DTH2_k127_6534070_25 Histidine kinase K07646 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009593,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031668,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071472,GO:0071496,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564 2.7.13.3 0.000003728 60.0
DTH2_k127_6534070_26 Beta-lactamase superfamily domain - - - 0.000003798 58.0
DTH2_k127_6534070_27 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000644 53.0
DTH2_k127_6534070_3 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 1.496e-204 647.0
DTH2_k127_6534070_4 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 601.0
DTH2_k127_6534070_5 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 365.0
DTH2_k127_6534070_6 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 303.0
DTH2_k127_6534070_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001165 285.0
DTH2_k127_6534070_8 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000009484 206.0
DTH2_k127_6534070_9 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000001567 199.0
DTH2_k127_6626250_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.461e-212 677.0
DTH2_k127_6626250_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 331.0
DTH2_k127_6626250_10 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000001363 175.0
DTH2_k127_6626250_11 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.000000000000000000000000000000000000000000002065 175.0
DTH2_k127_6626250_12 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000008903 158.0
DTH2_k127_6626250_13 ZPR1-like zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000005582 143.0
DTH2_k127_6626250_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000003091 137.0
DTH2_k127_6626250_15 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000007896 123.0
DTH2_k127_6626250_16 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003736 102.0
DTH2_k127_6626250_17 Pfam:DUF552 K09152 - - 0.000000000000000000000794 99.0
DTH2_k127_6626250_18 TIGRFAM bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.000000000000000000002386 105.0
DTH2_k127_6626250_19 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000002275 95.0
DTH2_k127_6626250_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 308.0
DTH2_k127_6626250_20 DNA-directed RNA polymerase subunit F K03051 - 2.7.7.6 0.0000000002118 67.0
DTH2_k127_6626250_21 metal-dependent membrane protease K07052 - - 0.0000000152 67.0
DTH2_k127_6626250_22 Methyltransferase domain - - - 0.00000004412 62.0
DTH2_k127_6626250_23 ribosomal small subunit binding - - - 0.00000006814 63.0
DTH2_k127_6626250_24 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.0000004406 61.0
DTH2_k127_6626250_25 PFAM transglutaminase domain protein - - - 0.000007047 59.0
DTH2_k127_6626250_26 FG-GAP repeat - - - 0.00001376 59.0
DTH2_k127_6626250_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003612 265.0
DTH2_k127_6626250_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008547 258.0
DTH2_k127_6626250_5 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001758 251.0
DTH2_k127_6626250_6 Helix-hairpin-helix motif K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
DTH2_k127_6626250_7 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001509 243.0
DTH2_k127_6626250_8 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000002335 223.0
DTH2_k127_6626250_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000001135 176.0
DTH2_k127_6778037_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 7.634e-217 689.0
DTH2_k127_6778037_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 567.0
DTH2_k127_6778037_10 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000001564 242.0
DTH2_k127_6778037_11 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000299 231.0
DTH2_k127_6778037_12 Fibronectin type III domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001123 253.0
DTH2_k127_6778037_13 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000004701 226.0
DTH2_k127_6778037_14 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000003615 224.0
DTH2_k127_6778037_15 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000009369 230.0
DTH2_k127_6778037_16 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000248 194.0
DTH2_k127_6778037_17 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000007306 184.0
DTH2_k127_6778037_18 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000002256 177.0
DTH2_k127_6778037_19 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000004291 132.0
DTH2_k127_6778037_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 473.0
DTH2_k127_6778037_20 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000001891 134.0
DTH2_k127_6778037_21 Helix-turn-helix XRE-family like proteins K03627 - - 0.00000000000000000000000008651 113.0
DTH2_k127_6778037_22 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000008237 119.0
DTH2_k127_6778037_23 4Fe-4S binding domain protein - - - 0.0000000000000000000005377 110.0
DTH2_k127_6778037_24 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000003006 76.0
DTH2_k127_6778037_25 Winged helix-turn-helix DNA-binding - - - 0.00001316 53.0
DTH2_k127_6778037_3 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 387.0
DTH2_k127_6778037_4 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 329.0
DTH2_k127_6778037_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 307.0
DTH2_k127_6778037_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 300.0
DTH2_k127_6778037_7 ATPases associated with a variety of cellular activities K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 286.0
DTH2_k127_6778037_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003875 273.0
DTH2_k127_6778037_9 membrane protein, hemolysin III homolog K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000007553 247.0
DTH2_k127_6818284_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 400.0
DTH2_k127_6818284_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 351.0
DTH2_k127_6818284_2 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 361.0
DTH2_k127_6818284_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000002312 153.0
DTH2_k127_6818284_4 Prenyltransferase and squalene oxidase repeat - - - 0.000000000000000000001253 111.0
DTH2_k127_6818284_5 Transglutaminase-like superfamily - - - 0.00000000000001455 86.0
DTH2_k127_6821636_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 494.0
DTH2_k127_6821636_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 453.0
DTH2_k127_6821636_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000003748 211.0
DTH2_k127_6821636_3 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000002446 197.0
DTH2_k127_6821636_4 NMD3 family K07562 - - 0.0000000000000000000000000000000000000000006442 170.0
DTH2_k127_6821636_5 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.000000000000000000000000002137 121.0
DTH2_k127_6821636_6 PFAM PKD domain containing protein - - - 0.0000000000000005724 89.0
DTH2_k127_6821636_7 PFAM PKD domain containing protein - - - 0.0000000000008042 78.0
DTH2_k127_6821636_8 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000005953 66.0
DTH2_k127_6821636_9 Glycosyl transferase family 2 - - - 0.0000000005612 70.0
DTH2_k127_6894811_0 DALR anticodon binding domain K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 438.0
DTH2_k127_6894811_1 ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007704 299.0
DTH2_k127_6894811_2 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000003147 209.0
DTH2_k127_6894811_3 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000000000001014 203.0
DTH2_k127_6894811_4 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000505 197.0
DTH2_k127_6894811_5 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000004289 207.0
DTH2_k127_6894811_6 von Willebrand factor (vWF) type A domain - - - 0.0000000000000007639 91.0
DTH2_k127_6917659_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 4.331e-199 628.0
DTH2_k127_6917659_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 589.0
DTH2_k127_6917659_10 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000003945 144.0
DTH2_k127_6917659_11 Thioredoxin - - - 0.0000000000000000000002022 102.0
DTH2_k127_6917659_12 Pkd domain containing protein - - - 0.00000000000000000001024 109.0
DTH2_k127_6917659_13 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000004448 107.0
DTH2_k127_6917659_14 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.0000000000000000338 95.0
DTH2_k127_6917659_15 Belongs to the ompA family K20276 - - 0.0000000001376 68.0
DTH2_k127_6917659_16 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000006165 63.0
DTH2_k127_6917659_17 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.000001857 62.0
DTH2_k127_6917659_18 Thrombospondin type 3 repeat - - - 0.000008066 61.0
DTH2_k127_6917659_2 phosphoribosylamine-glycine ligase activity K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 464.0
DTH2_k127_6917659_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 312.0
DTH2_k127_6917659_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 317.0
DTH2_k127_6917659_5 Enoyl-(Acyl carrier protein) reductase K00023,K00059,K04708 - 1.1.1.100,1.1.1.102,1.1.1.36 0.00000000000000000000000000000000000000000000000000000002905 206.0
DTH2_k127_6917659_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000208 195.0
DTH2_k127_6917659_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000001261 156.0
DTH2_k127_6917659_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000001763 172.0
DTH2_k127_6917659_9 PFAM Desulfoferrodoxin, ferrous iron-binding region K05919 - 1.15.1.2 0.0000000000000000000000000000000000002684 144.0
DTH2_k127_7070144_0 domain, Protein K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.00000000000000000000000000000000009159 146.0
DTH2_k127_715337_0 Heat shock 70 kDa protein K04043 - - 1.068e-243 767.0
DTH2_k127_715337_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 311.0
DTH2_k127_715337_2 Fibronectin type III domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000198 261.0
DTH2_k127_715337_3 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000003158 204.0
DTH2_k127_715337_4 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000008026 136.0
DTH2_k127_715337_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000004407 97.0
DTH2_k127_715337_6 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000753 70.0
DTH2_k127_715337_7 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000007772 53.0
DTH2_k127_715337_8 peptidyl-tyrosine sulfation - - - 0.00005278 55.0
DTH2_k127_715337_9 PQQ-like domain - - - 0.0001646 55.0
DTH2_k127_7213546_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000127 137.0
DTH2_k127_7256573_0 CarboxypepD_reg-like domain - - - 0.0004263 54.0
DTH2_k127_7297444_0 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 398.0
DTH2_k127_7297444_1 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 311.0
DTH2_k127_7297444_10 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.00000000000000000000000000001438 126.0
DTH2_k127_7297444_12 transferase activity, transferring glycosyl groups - - - 0.00000000003318 74.0
DTH2_k127_7297444_13 Cellulose-binding domain K01183,K21606 - 3.2.1.14,3.2.1.202 0.0000005664 63.0
DTH2_k127_7297444_14 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K01091 - 3.1.3.18 0.0000008265 59.0
DTH2_k127_7297444_3 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002585 289.0
DTH2_k127_7297444_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001786 259.0
DTH2_k127_7297444_5 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000002802 204.0
DTH2_k127_7297444_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000001138 162.0
DTH2_k127_7297444_7 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000001854 160.0
DTH2_k127_7297444_8 Pfam:KaiC - - - 0.000000000000000000000000000000000000002033 157.0
DTH2_k127_7297444_9 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000001032 146.0
DTH2_k127_7307005_0 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 424.0
DTH2_k127_7394419_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1133.0
DTH2_k127_7394419_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 408.0
DTH2_k127_7394419_10 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0005507 48.0
DTH2_k127_7394419_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 359.0
DTH2_k127_7394419_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.0000000000000000000000000000000000007648 142.0
DTH2_k127_7394419_4 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000003673 149.0
DTH2_k127_7394419_5 Putative small multi-drug export protein - - - 0.00000000000000000000000000000000005401 143.0
DTH2_k127_7394419_6 Pfam:KaiC - - - 0.00000000000000000000000000000001024 136.0
DTH2_k127_7394419_7 Muskelin N-terminus - - - 0.0000000004962 74.0
DTH2_k127_7394419_8 ATP-dependent DNA helicase (RecQ) K03654 - 3.6.4.12 0.000000004807 66.0
DTH2_k127_7394419_9 protein ubiquitination - - - 0.00008829 57.0
DTH2_k127_7453219_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 443.0
DTH2_k127_7453219_1 FlgD Ig-like domain K15924 - 3.2.1.136 0.0000000001298 75.0
DTH2_k127_7453219_2 PFAM metallophosphoesterase - - - 0.0000107 59.0
DTH2_k127_7476822_0 DEAD DEAH box helicase domain protein K03724 - - 5.777e-200 660.0
DTH2_k127_7476822_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 445.0
DTH2_k127_7476822_10 NUDIX domain - - - 0.000000000000000000000003659 107.0
DTH2_k127_7476822_11 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000002668 97.0
DTH2_k127_7476822_12 - - - - 0.00000000000000006098 83.0
DTH2_k127_7476822_13 Thioredoxin-like - - - 0.00000000000001231 82.0
DTH2_k127_7476822_17 - - - - 0.0000000002217 64.0
DTH2_k127_7476822_18 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000103 61.0
DTH2_k127_7476822_19 ORF located using Blastx - - - 0.0000004498 53.0
DTH2_k127_7476822_2 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 390.0
DTH2_k127_7476822_21 Tetratricopeptide repeat K15176 GO:0000122,GO:0000428,GO:0000785,GO:0000993,GO:0001098,GO:0001099,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0008023,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009909,GO:0009910,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016020,GO:0016043,GO:0016569,GO:0016570,GO:0016571,GO:0016591,GO:0016593,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0030880,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032270,GO:0032784,GO:0032786,GO:0032968,GO:0032991,GO:0033043,GO:0033044,GO:0034243,GO:0034968,GO:0035327,GO:0036211,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048581,GO:0048831,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051569,GO:0051571,GO:0055029,GO:0060255,GO:0061695,GO:0065007,GO:0070013,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:1901564,GO:1902275,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1905269,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2000241,GO:2000242,GO:2001141,GO:2001252 - 0.0003274 55.0
DTH2_k127_7476822_22 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0003797 52.0
DTH2_k127_7476822_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 381.0
DTH2_k127_7476822_4 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 329.0
DTH2_k127_7476822_5 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007137 279.0
DTH2_k127_7476822_6 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000003728 228.0
DTH2_k127_7476822_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000003543 208.0
DTH2_k127_7476822_8 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000004485 152.0
DTH2_k127_7476822_9 alkyl hydroperoxide reductase activity - - - 0.00000000000000000000000005176 116.0
DTH2_k127_7610059_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 345.0
DTH2_k127_7610059_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 269.0
DTH2_k127_7610059_10 Male sterility protein K01710 - 4.2.1.46 0.000000000000000000000000000000004976 147.0
DTH2_k127_7610059_11 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000002473 108.0
DTH2_k127_7610059_12 SCP-2 sterol transfer family - - - 0.00000003048 61.0
DTH2_k127_7610059_13 Carbohydrate binding domain, family 6 - - - 0.0000002597 65.0
DTH2_k127_7610059_14 TPR repeat-containing protein K07452 - - 0.000002773 59.0
DTH2_k127_7610059_15 - - - - 0.00003488 53.0
DTH2_k127_7610059_16 NYN domain - - - 0.0001157 51.0
DTH2_k127_7610059_2 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000351 248.0
DTH2_k127_7610059_3 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000003633 234.0
DTH2_k127_7610059_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.00000000000000000000000000000000000000000000000000000009008 210.0
DTH2_k127_7610059_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000005098 207.0
DTH2_k127_7610059_6 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000004016 218.0
DTH2_k127_7610059_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000008882 175.0
DTH2_k127_7610059_8 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000000257 158.0
DTH2_k127_7610059_9 - - - - 0.0000000000000000000000000000000000007644 144.0
DTH2_k127_7699644_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 577.0
DTH2_k127_7699644_1 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 469.0
DTH2_k127_7699644_2 Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 472.0
DTH2_k127_7699644_3 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002226 254.0
DTH2_k127_7699644_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000005552 110.0
DTH2_k127_7699644_5 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.0000000000000004526 81.0
DTH2_k127_7699644_6 - - - - 0.00000000001709 69.0
DTH2_k127_7699644_7 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - 0.0000000009585 74.0
DTH2_k127_7699644_8 Tetratricopeptide repeat - - - 0.000116 53.0
DTH2_k127_7760191_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 4.371e-209 669.0
DTH2_k127_7760191_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 563.0
DTH2_k127_7760191_10 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 307.0
DTH2_k127_7760191_11 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001504 276.0
DTH2_k127_7760191_12 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000002679 272.0
DTH2_k127_7760191_13 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000001809 242.0
DTH2_k127_7760191_14 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000002199 195.0
DTH2_k127_7760191_15 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000002172 173.0
DTH2_k127_7760191_16 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000003203 181.0
DTH2_k127_7760191_17 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000143 166.0
DTH2_k127_7760191_18 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000001767 164.0
DTH2_k127_7760191_19 FG-GAP repeat - - - 0.0000000000000000000000000000000000244 158.0
DTH2_k127_7760191_2 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 552.0
DTH2_k127_7760191_20 protein conserved in archaea K09746 - - 0.0000000000000000000000002213 117.0
DTH2_k127_7760191_21 HTH DNA binding domain - - - 0.00000000000000000000008996 107.0
DTH2_k127_7760191_22 PFAM TPR repeat-containing protein - - - 0.0000000000000000000003829 111.0
DTH2_k127_7760191_23 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000005009 93.0
DTH2_k127_7760191_24 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.000000000000000385 92.0
DTH2_k127_7760191_25 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000003941 74.0
DTH2_k127_7760191_26 - - - - 0.00000000000008618 75.0
DTH2_k127_7760191_27 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000004514 64.0
DTH2_k127_7760191_28 Parallel beta-helix repeats - - - 0.00000003725 68.0
DTH2_k127_7760191_29 Glycosyl transferase, family 2 - - - 0.00002849 57.0
DTH2_k127_7760191_3 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 516.0
DTH2_k127_7760191_4 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 473.0
DTH2_k127_7760191_5 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 455.0
DTH2_k127_7760191_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 411.0
DTH2_k127_7760191_7 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 393.0
DTH2_k127_7760191_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 368.0
DTH2_k127_7760191_9 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 379.0
DTH2_k127_7803613_0 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 476.0
DTH2_k127_7803613_1 phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000001891 196.0
DTH2_k127_7803613_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000156 143.0
DTH2_k127_7803613_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000001631 115.0
DTH2_k127_7803613_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.00001355 51.0
DTH2_k127_782362_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 431.0
DTH2_k127_782362_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 295.0
DTH2_k127_782362_2 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000001891 218.0
DTH2_k127_782362_3 4-alpha-L-fucosyltransferase glycosyl transferase group 56 - - - 0.0000000000000000000000000000000000000000000000000000000004395 216.0
DTH2_k127_782362_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000001565 207.0
DTH2_k127_782362_5 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000002046 138.0
DTH2_k127_788726_0 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003164 259.0
DTH2_k127_788726_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000107 157.0
DTH2_k127_788726_2 Flavodoxin - - - 0.00000000002683 67.0
DTH2_k127_788726_3 Protein of unknown function (DUF3068) - - - 0.00008913 55.0
DTH2_k127_7904814_0 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0 1291.0
DTH2_k127_7904814_1 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 532.0
DTH2_k127_7904814_10 Domain of unknown function (DUF4082) - - - 0.000000000003834 80.0
DTH2_k127_7904814_11 exo-alpha-(2->6)-sialidase activity - - - 0.0000000006571 74.0
DTH2_k127_7904814_12 - - - - 0.0001793 55.0
DTH2_k127_7904814_2 Hydrogenase expression formation protein (HypD) K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 398.0
DTH2_k127_7904814_3 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01954,K11540,K11541 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009987,GO:0016053,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019627,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.1.3.2,3.5.2.3,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 386.0
DTH2_k127_7904814_4 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000007249 237.0
DTH2_k127_7904814_5 spore germination K03298 - - 0.00000000000000000000000000000000000000000000000000000002636 207.0
DTH2_k127_7904814_6 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000008706 204.0
DTH2_k127_7904814_7 Belongs to the UPF0178 family - - - 0.0000000000000000000000000000000000000008378 151.0
DTH2_k127_7904814_8 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000001035 88.0
DTH2_k127_7904814_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000002236 72.0
DTH2_k127_806879_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 609.0
DTH2_k127_806879_1 Flavodoxin - - - 0.00000000000000000000000000000000000003275 151.0
DTH2_k127_806879_2 YEATS family - - - 0.000000000001884 72.0
DTH2_k127_806879_3 transporter - - - 0.0000000002116 74.0
DTH2_k127_826859_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 1.288e-214 681.0
DTH2_k127_826859_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 439.0
DTH2_k127_826859_2 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 381.0
DTH2_k127_826859_3 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 310.0
DTH2_k127_826859_4 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000001344 172.0
DTH2_k127_826859_5 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000000004643 124.0
DTH2_k127_8364396_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1369.0
DTH2_k127_8364396_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1202.0
DTH2_k127_8364396_10 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000000000002633 207.0
DTH2_k127_8364396_11 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000007967 162.0
DTH2_k127_8364396_12 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000003563 137.0
DTH2_k127_8364396_13 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000003122 96.0
DTH2_k127_8364396_14 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000005278 100.0
DTH2_k127_8364396_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000009883 88.0
DTH2_k127_8364396_16 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.0000000000000002443 83.0
DTH2_k127_8364396_17 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.0000000003921 63.0
DTH2_k127_8364396_18 archaeal coiled-coil protein - - - 0.00007066 54.0
DTH2_k127_8364396_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1135.0
DTH2_k127_8364396_3 AAA domain K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 538.0
DTH2_k127_8364396_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 451.0
DTH2_k127_8364396_5 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 378.0
DTH2_k127_8364396_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 379.0
DTH2_k127_8364396_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 331.0
DTH2_k127_8364396_8 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 296.0
DTH2_k127_8364396_9 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000001808 243.0
DTH2_k127_8429284_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 379.0
DTH2_k127_8429284_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0005948 42.0
DTH2_k127_8456218_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 6.534e-235 738.0
DTH2_k127_8456218_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.604e-206 661.0
DTH2_k127_8456218_10 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000001389 194.0
DTH2_k127_8456218_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000112 167.0
DTH2_k127_8456218_12 Heterodisulfide reductase, subunit B K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000002944 86.0
DTH2_k127_8456218_13 FtsX-like permease family K02004 - - 0.000000004219 68.0
DTH2_k127_8456218_2 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 490.0
DTH2_k127_8456218_3 PFAM AMP-dependent synthetase K01895,K01896 - 6.2.1.1,6.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 478.0
DTH2_k127_8456218_4 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 376.0
DTH2_k127_8456218_5 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 315.0
DTH2_k127_8456218_6 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000004489 223.0
DTH2_k127_8456218_7 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000006076 218.0
DTH2_k127_8456218_8 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000004025 201.0
DTH2_k127_8456218_9 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000003468 192.0
DTH2_k127_8583824_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 1396.0
DTH2_k127_8583824_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 430.0
DTH2_k127_8594698_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.312e-248 782.0
DTH2_k127_8594698_1 Belongs to the V-ATPase 116 kDa subunit family K02123 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000241 243.0
DTH2_k127_8594698_2 Belongs to the V-ATPase proteolipid subunit family K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 - 0.000000000000000000000001116 113.0
DTH2_k127_8594698_3 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000001625 85.0
DTH2_k127_8594698_4 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000006774 73.0
DTH2_k127_8594698_5 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.000000001196 68.0
DTH2_k127_8604387_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 440.0
DTH2_k127_8604387_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 407.0
DTH2_k127_8604387_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000008154 98.0
DTH2_k127_8604387_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000002598 92.0
DTH2_k127_8604387_12 HTH DNA binding domain - - - 0.000000000000118 80.0
DTH2_k127_8604387_13 PFAM NHL repeat containing protein - - - 0.00000000000707 80.0
DTH2_k127_8604387_14 COG3364 Zn-ribbon containing protein K07163 - - 0.0000001147 61.0
DTH2_k127_8604387_15 FG-GAP repeat - - - 0.000101 57.0
DTH2_k127_8604387_16 deoxyribonuclease I activity - - - 0.0002138 50.0
DTH2_k127_8604387_2 GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009521 277.0
DTH2_k127_8604387_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005972 272.0
DTH2_k127_8604387_4 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000845 278.0
DTH2_k127_8604387_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000033 196.0
DTH2_k127_8604387_6 COG1056 Nicotinamide mononucleotide adenylyltransferase K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000209 194.0
DTH2_k127_8604387_7 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000002686 134.0
DTH2_k127_8604387_8 Domain of unknown function (DUF1858) - - - 0.0000000000000000000002388 97.0
DTH2_k127_8604387_9 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000001113 100.0
DTH2_k127_8624486_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 591.0
DTH2_k127_8624486_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 567.0
DTH2_k127_8624486_10 endonuclease III K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 292.0
DTH2_k127_8624486_11 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007179 280.0
DTH2_k127_8624486_12 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 278.0
DTH2_k127_8624486_13 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001222 266.0
DTH2_k127_8624486_14 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004679 286.0
DTH2_k127_8624486_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
DTH2_k127_8624486_16 Protein conserved in bacteria K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000001186 249.0
DTH2_k127_8624486_17 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000006712 239.0
DTH2_k127_8624486_18 DEAD_2 K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000003136 243.0
DTH2_k127_8624486_19 Mechanosensitive ion channel K03442,K05802,K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000454 234.0
DTH2_k127_8624486_2 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 494.0
DTH2_k127_8624486_20 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.0000000000000000000000000000000000000000000000000000000009191 211.0
DTH2_k127_8624486_21 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000261 167.0
DTH2_k127_8624486_22 lycopene cyclase - - - 0.0000000000000000000000000000000000000000005969 166.0
DTH2_k127_8624486_23 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.0000000000000000000000000000000000000003352 158.0
DTH2_k127_8624486_24 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000001717 159.0
DTH2_k127_8624486_25 periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000004457 154.0
DTH2_k127_8624486_26 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000007057 147.0
DTH2_k127_8624486_27 Transcriptional regulator K07730 - - 0.000000000000000000008426 103.0
DTH2_k127_8624486_28 Subtilase family - - - 0.0000000000000002012 87.0
DTH2_k127_8624486_29 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000203 91.0
DTH2_k127_8624486_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 492.0
DTH2_k127_8624486_30 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000001112 80.0
DTH2_k127_8624486_31 extracellular matrix structural constituent - - - 0.000000002702 72.0
DTH2_k127_8624486_32 - - - - 0.000006434 55.0
DTH2_k127_8624486_33 Belongs to the arginase family K01480 - 3.5.3.11 0.0003156 48.0
DTH2_k127_8624486_4 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 455.0
DTH2_k127_8624486_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 373.0
DTH2_k127_8624486_6 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 360.0
DTH2_k127_8624486_7 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 382.0
DTH2_k127_8624486_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 338.0
DTH2_k127_8624486_9 Glycosyltransferase like family 2 K00721 GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0004582,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006486,GO:0006493,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009247,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0019637,GO:0031984,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0070085,GO:0071704,GO:0090407,GO:0097502,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 325.0
DTH2_k127_8638631_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 576.0
DTH2_k127_8638631_1 AMP-binding enzyme K22319 - 6.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 531.0
DTH2_k127_8638631_10 Right handed beta helix region - - - 0.000000000000000000000000001712 127.0
DTH2_k127_8638631_11 - - - - 0.00000000000008113 85.0
DTH2_k127_8638631_12 protein conserved in archaea - - - 0.0000000000267 75.0
DTH2_k127_8638631_2 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 441.0
DTH2_k127_8638631_3 3-Beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 374.0
DTH2_k127_8638631_4 Alpha beta hydrolase K01563,K22318 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 335.0
DTH2_k127_8638631_5 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648,K22317 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 304.0
DTH2_k127_8638631_6 Copper amine oxidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001829 226.0
DTH2_k127_8638631_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000001297 195.0
DTH2_k127_8638631_8 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000004552 185.0
DTH2_k127_8638631_9 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000005067 148.0
DTH2_k127_8756414_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.087e-218 693.0
DTH2_k127_8756414_1 cell volume homeostasis K03316,K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 393.0
DTH2_k127_8756414_10 - K00960 - 2.7.7.6 0.000000000000000007451 85.0
DTH2_k127_8756414_11 SRPBCC superfamily protein - - - 0.00002373 52.0
DTH2_k127_8756414_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 359.0
DTH2_k127_8756414_3 Methyltransferase type 11 K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 353.0
DTH2_k127_8756414_4 UbiE COQ5 methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 340.0
DTH2_k127_8756414_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000001398 224.0
DTH2_k127_8756414_6 - - - - 0.00000000000000000000000000000000000000000000000000000001514 201.0
DTH2_k127_8756414_7 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000009528 178.0
DTH2_k127_8756414_8 SnoaL-like domain - - - 0.000000000000000000000000000000000162 137.0
DTH2_k127_8756414_9 - - - - 0.0000000000000000000000000000003682 128.0
DTH2_k127_8770402_0 TIGRFAM small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 391.0
DTH2_k127_8770402_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000001741 204.0
DTH2_k127_8770402_10 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.0000000000000001857 90.0
DTH2_k127_8770402_11 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000142 75.0
DTH2_k127_8770402_12 recombinase XerD K04763 - - 0.0000000002332 67.0
DTH2_k127_8770402_2 metal-dependent hydrolase (Urease superfamily) K07049 - - 0.00000000000000000000000000000000000000000000000008015 188.0
DTH2_k127_8770402_3 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000003014 179.0
DTH2_k127_8770402_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000003904 163.0
DTH2_k127_8770402_5 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000005592 151.0
DTH2_k127_8770402_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000006809 110.0
DTH2_k127_8770402_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000005085 111.0
DTH2_k127_8770402_8 Binds to the 23S rRNA K02896 - - 0.0000000000000000007453 89.0
DTH2_k127_8770402_9 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.0000000000000001086 92.0
DTH2_k127_8779568_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1137.0
DTH2_k127_8779568_1 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 459.0
DTH2_k127_8779568_2 TIGRFAM MIP family channel K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 293.0
DTH2_k127_8779568_3 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 270.0
DTH2_k127_8779568_4 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000006402 280.0
DTH2_k127_8779568_5 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000002683 193.0
DTH2_k127_8779568_6 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000007671 80.0
DTH2_k127_8804502_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 597.0
DTH2_k127_8804502_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 442.0
DTH2_k127_8804502_10 - - - - 0.00000000000001258 78.0
DTH2_k127_8804502_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 442.0
DTH2_k127_8804502_3 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 424.0
DTH2_k127_8804502_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 379.0
DTH2_k127_8804502_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003773 279.0
DTH2_k127_8804502_6 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000007083 187.0
DTH2_k127_8804502_7 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000001811 192.0
DTH2_k127_8804502_8 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.0000000000000000000000000000000002153 135.0
DTH2_k127_8804502_9 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000428 133.0
DTH2_k127_8871087_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 416.0
DTH2_k127_8871087_1 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 392.0
DTH2_k127_8871087_2 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000003288 276.0
DTH2_k127_8871087_3 PFAM ABC transporter related K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000007681 210.0
DTH2_k127_8871087_4 Metalloenzyme superfamily - - - 0.00000000000000000000002357 115.0
DTH2_k127_8871087_5 transcriptional - - - 0.0000000000002614 74.0
DTH2_k127_8871087_6 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.000000000006898 74.0
DTH2_k127_8871087_7 CAAX protease self-immunity - - - 0.00000004991 64.0
DTH2_k127_8871087_8 ABC-type cobalt transport system permease component CbiQ and related transporters K16785 - - 0.000000937 60.0
DTH2_k127_8871087_9 Oxidoreductase molybdopterin binding domain - - - 0.000008079 55.0
DTH2_k127_892097_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 7.459e-261 835.0
DTH2_k127_892097_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 404.0
DTH2_k127_892097_10 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000002851 169.0
DTH2_k127_892097_11 Transcriptional regulator, ArsR family - - - 0.00000000000000000000000000000000000000005638 157.0
DTH2_k127_892097_12 Pfam:KaiC - - - 0.00000000000000000000000000000000000000009282 165.0
DTH2_k127_892097_13 PAP2 superfamily - - - 0.000000000000000000000000000361 126.0
DTH2_k127_892097_14 Fumarylacetoacetate (FAA) hydrolase family K01557 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0047621,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.5 0.0000000000000000002298 96.0
DTH2_k127_892097_15 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000893 72.0
DTH2_k127_892097_16 metallocarboxypeptidase activity - - - 0.00000000000381 80.0
DTH2_k127_892097_17 protein conserved in archaea - - - 0.000000000008046 80.0
DTH2_k127_892097_18 - - - - 0.000000007143 62.0
DTH2_k127_892097_2 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 344.0
DTH2_k127_892097_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 335.0
DTH2_k127_892097_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 302.0
DTH2_k127_892097_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000003209 230.0
DTH2_k127_892097_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000021 219.0
DTH2_k127_892097_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000004713 219.0
DTH2_k127_892097_8 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000007143 164.0
DTH2_k127_892097_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000001051 167.0
DTH2_k127_8970875_0 Putative Ig domain - - - 0.000001099 62.0
DTH2_k127_8980615_0 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000269 115.0
DTH2_k127_9086670_0 Cadherin repeats. - - - 0.000000000000000000000000000000000003683 160.0
DTH2_k127_9086670_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000007023 93.0
DTH2_k127_9086670_2 Belongs to the peptidase S8 family K14645 - - 0.00009486 56.0
DTH2_k127_9089647_0 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000000000000000000000002304 230.0
DTH2_k127_9089647_1 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000002872 146.0
DTH2_k127_9089647_2 PFAM Uncharacterised protein family UPF0157 - - - 0.0000000000000000000004913 100.0
DTH2_k127_9089647_3 Periplasmic copper-binding protein (NosD) - - - 0.00001006 58.0
DTH2_k127_9100738_0 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 423.0
DTH2_k127_9100738_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000001402 223.0
DTH2_k127_9100738_10 FtsX-like permease family K02004 - - 0.0000000001076 70.0
DTH2_k127_9100738_11 - - - - 0.000000003651 59.0
DTH2_k127_9100738_12 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000217 51.0
DTH2_k127_9100738_13 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000005413 55.0
DTH2_k127_9100738_2 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000005571 201.0
DTH2_k127_9100738_3 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.00000000000000000000000000000000000000000000000005163 198.0
DTH2_k127_9100738_4 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000006447 169.0
DTH2_k127_9100738_5 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000005524 160.0
DTH2_k127_9100738_6 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000000000000000000000001048 117.0
DTH2_k127_9100738_7 RNA-binding protein of the translin family K07477 - - 0.000000000000000004898 96.0
DTH2_k127_9100738_8 PRC-barrel domain - - - 0.00000000000003498 79.0
DTH2_k127_9100738_9 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.00000000004099 74.0
DTH2_k127_9152740_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1272.0
DTH2_k127_9152740_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 407.0
DTH2_k127_9152740_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.000000000000000003832 87.0
DTH2_k127_9152740_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000002988 70.0
DTH2_k127_9152740_12 - - - - 0.000000002187 64.0
DTH2_k127_9152740_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000316 59.0
DTH2_k127_9152740_14 COG3063 Tfp pilus assembly protein PilF K02656 - - 0.00004878 52.0
DTH2_k127_9152740_15 glutamate synthase alpha subunit domain protein - - - 0.0001136 52.0
DTH2_k127_9152740_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 319.0
DTH2_k127_9152740_3 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 274.0
DTH2_k127_9152740_4 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000002254 211.0
DTH2_k127_9152740_5 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000306 179.0
DTH2_k127_9152740_6 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000008396 147.0
DTH2_k127_9152740_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000001226 150.0
DTH2_k127_9152740_8 Peptidase family M50 - - - 0.000000000000000000000000000000000008359 146.0
DTH2_k127_9152740_9 PFAM Protein kinase domain - - - 0.000000000000000000000000005953 126.0
DTH2_k127_922561_0 Amino acid permease - - - 1.685e-194 631.0
DTH2_k127_922561_2 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004515 280.0
DTH2_k127_922561_3 - - - - 0.00000000000000000000000000000000001113 145.0
DTH2_k127_922561_4 ABC-type Na efflux pump, permease K01992 - - 0.000000001897 70.0
DTH2_k127_9264166_0 Class II Aldolase and Adducin N-terminal domain K01629 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.19 0.0000000000000000005937 94.0
DTH2_k127_9264166_1 Papain family cysteine protease - - - 0.00000000002959 77.0
DTH2_k127_9322419_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.292e-197 632.0
DTH2_k127_9322419_1 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 409.0
DTH2_k127_9322419_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000007842 180.0
DTH2_k127_9322419_11 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000007444 175.0
DTH2_k127_9322419_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001773 166.0
DTH2_k127_9322419_13 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000005722 166.0
DTH2_k127_9322419_14 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000001083 167.0
DTH2_k127_9322419_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000006096 158.0
DTH2_k127_9322419_16 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000004455 144.0
DTH2_k127_9322419_17 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000004822 137.0
DTH2_k127_9322419_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000005292 134.0
DTH2_k127_9322419_19 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000004658 126.0
DTH2_k127_9322419_2 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001643 274.0
DTH2_k127_9322419_20 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003736 115.0
DTH2_k127_9322419_21 ribosomal protein L24 K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000105 101.0
DTH2_k127_9322419_22 ribosomal protein S14 K02954 - - 0.0000000000000000001125 91.0
DTH2_k127_9322419_23 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001922 89.0
DTH2_k127_9322419_24 Ribosomal L29 protein K02904 - - 0.0000000000000001211 81.0
DTH2_k127_9322419_25 CarboxypepD_reg-like domain K13276 - - 0.000000000006037 80.0
DTH2_k127_9322419_26 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000001992 66.0
DTH2_k127_9322419_3 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001782 275.0
DTH2_k127_9322419_4 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009458 268.0
DTH2_k127_9322419_5 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000008251 259.0
DTH2_k127_9322419_6 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000004882 227.0
DTH2_k127_9322419_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007427 210.0
DTH2_k127_9322419_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000007826 194.0
DTH2_k127_9322419_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000007261 190.0
DTH2_k127_9389409_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 406.0
DTH2_k127_9389409_1 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000007459 183.0
DTH2_k127_9389409_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000642 179.0
DTH2_k127_9389409_3 Flavodoxin - - - 0.0000000000000000000000000005362 120.0
DTH2_k127_9389409_4 - - - - 0.00000002735 61.0
DTH2_k127_943608_0 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 475.0
DTH2_k127_943608_1 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 420.0
DTH2_k127_943608_11 DNA integration K04763 - - 0.00001266 56.0
DTH2_k127_943608_2 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000249 236.0
DTH2_k127_943608_3 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005964 247.0
DTH2_k127_943608_4 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000003649 234.0
DTH2_k127_943608_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000001403 177.0
DTH2_k127_943608_6 metallophosphoesterase K07098 - - 0.000000000000000000000000000000000001428 153.0
DTH2_k127_943608_7 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000005019 141.0
DTH2_k127_943608_8 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000004887 116.0
DTH2_k127_943608_9 EamA-like transporter family - - - 0.0000000000000002069 90.0
DTH2_k127_9471160_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 7.291e-212 672.0
DTH2_k127_9471160_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 413.0
DTH2_k127_9471160_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002359 250.0
DTH2_k127_9471160_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000104 222.0
DTH2_k127_9471160_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000002791 188.0
DTH2_k127_9471160_5 transcriptional regulator - - - 0.000000000000000000009833 100.0
DTH2_k127_9585984_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0 1145.0
DTH2_k127_9585984_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.122e-289 896.0
DTH2_k127_9585984_2 Putative diphthamide synthesis protein K07561 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016765,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0048037,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000009114 219.0
DTH2_k127_9585984_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000003678 171.0
DTH2_k127_9585984_4 FMN binding - - - 0.00000000000000000000008724 104.0
DTH2_k127_9585984_5 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000001285 76.0
DTH2_k127_9585984_6 COG NOG14600 non supervised orthologous group - - - 0.00006198 49.0
DTH2_k127_9603410_0 Type II/IV secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 497.0
DTH2_k127_9603410_1 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 382.0
DTH2_k127_9603410_10 Tetratricopeptide repeat K12869 - - 0.0000005929 62.0
DTH2_k127_9603410_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002371 272.0
DTH2_k127_9603410_3 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000004908 172.0
DTH2_k127_9603410_4 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000000004123 174.0
DTH2_k127_9603410_5 Type II secretion system K07333 - - 0.00000000000000000000000000000000001721 149.0
DTH2_k127_9603410_6 Exonuclease - - - 0.000000000000000000000000000000004287 135.0
DTH2_k127_9603410_7 CAAX protease self-immunity - - - 0.00000000000000000000003208 117.0
DTH2_k127_9603410_8 Small multi-drug export protein - - - 0.00000000000000001759 95.0
DTH2_k127_9603410_9 Subtilase family - - - 0.0000001217 55.0
DTH2_k127_9638961_0 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000004806 169.0
DTH2_k127_9638961_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000002471 145.0
DTH2_k127_9638961_2 acetyltransferase - - - 0.0000000000000000000002352 102.0
DTH2_k127_9638961_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000002486 88.0
DTH2_k127_9638961_4 Flavodoxin - - - 0.000000000001847 69.0
DTH2_k127_9668424_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 456.0
DTH2_k127_9668424_1 COG3291 FOG PKD repeat K01387 GO:0005575,GO:0005576 3.4.24.3 0.00000000000002071 86.0
DTH2_k127_9682098_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 2.627e-313 974.0
DTH2_k127_9682098_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.764e-255 808.0
DTH2_k127_9682098_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.791e-212 665.0
DTH2_k127_9682098_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 298.0
DTH2_k127_9682098_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000004871 229.0
DTH2_k127_9682098_5 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003603 160.0
DTH2_k127_9682098_6 Pfam Methyltransferase - - - 0.0000000000000000000000000000008927 137.0
DTH2_k127_9682098_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000008713 85.0
DTH2_k127_9682098_8 transporter - - - 0.000000005646 68.0
DTH2_k127_9682098_9 Antibiotic biosynthesis monooxygenase - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.00001748 50.0
DTH2_k127_9695213_0 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 462.0
DTH2_k127_9695213_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001971 263.0
DTH2_k127_9695213_2 Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000004826 242.0
DTH2_k127_9695213_3 Dystroglycan-type cadherin-like domains. - - - 0.0000000000000000000000000000000000000000000000000000001452 223.0
DTH2_k127_9695213_5 myosin light chain kinase activity K12567 - 2.7.11.1 0.000000000000000000000000000000000000005161 169.0
DTH2_k127_9695213_6 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.00000000000006701 87.0
DTH2_k127_9710203_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 328.0
DTH2_k127_9710203_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000001504 211.0
DTH2_k127_9710203_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000003522 107.0
DTH2_k127_9710203_3 oligopeptide transporter, OPT family - - - 0.00000000000000003872 96.0
DTH2_k127_9710203_4 integral membrane protein K07027 - - 0.000000000000003142 87.0
DTH2_k127_9710203_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000001722 67.0
DTH2_k127_9710203_6 Protein of unknown function (DUF2797) - - - 0.0000003691 61.0
DTH2_k127_9710203_7 arabinogalactan K01224 - 3.2.1.89 0.00001186 59.0
DTH2_k127_9821845_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 387.0
DTH2_k127_9821845_1 Pyruvate kinase, barrel domain K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 364.0
DTH2_k127_9821845_10 Copper chaperone PCu(A)C - - - 0.00000007731 66.0
DTH2_k127_9821845_11 - - - - 0.0000009265 63.0
DTH2_k127_9821845_12 domain protein K13735,K17624 - 3.2.1.97 0.000006807 60.0
DTH2_k127_9821845_13 Beta-L-arabinofuranosidase, GH127 - - - 0.00004871 56.0
DTH2_k127_9821845_2 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000003587 260.0
DTH2_k127_9821845_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001294 249.0
DTH2_k127_9821845_4 Domain of unknown function (DUF1905) - - - 0.000000000000000000000003485 106.0
DTH2_k127_9821845_5 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000007931 120.0
DTH2_k127_9821845_6 Domain of unknown function (DUF296) K06934 - - 0.0000000000000007543 83.0
DTH2_k127_9821845_7 WD-40 repeat - - - 0.0000000003381 74.0
DTH2_k127_9821845_8 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.000000000897 71.0
DTH2_k127_9821845_9 Putative zinc- or iron-chelating domain K06940 - - 0.000000001638 65.0
DTH2_k127_9951891_0 aconitate hydratase K01681 - 4.2.1.3 4.153e-283 883.0
DTH2_k127_9951891_1 ATP-citrate synthase K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 1.438e-228 722.0
DTH2_k127_9951891_10 Citrate lyase acyl carrier protein K01646 - - 0.00000003091 59.0
DTH2_k127_9951891_11 - - - - 0.00001897 49.0
DTH2_k127_9951891_2 Citrate lyase alpha subunit K01643 - 2.8.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 502.0
DTH2_k127_9951891_3 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 466.0
DTH2_k127_9951891_4 ATP citrate lyase citrate-binding K15231 - 2.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 450.0
DTH2_k127_9951891_5 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
DTH2_k127_9951891_6 Exonuclease SbcC K03546 - - 0.000000000000000000000000000000000000000000000000000002969 216.0
DTH2_k127_9951891_7 MgtC family K07507 - - 0.0000000000000000000000003781 113.0
DTH2_k127_9951891_8 COG1522 Transcriptional regulators - - - 0.000000000000000000001257 108.0
DTH2_k127_9951891_9 PFAM plasmid stabilization system K06218 - - 0.00000000000003796 75.0