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Overview

ID MAG00767
Name DTH2_bin.25
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order SZUA-242
Family SZUA-242
Genus
Species
Assembly information
Completeness (%) 72.44
Contamination (%) 1.82
GC content (%) 61.0
N50 (bp) 4,334
Genome size (bp) 1,916,897

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1991

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10024083_0 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000299 210.0
DTH2_k127_10024083_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000004648 177.0
DTH2_k127_10054566_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 587.0
DTH2_k127_10054566_1 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 301.0
DTH2_k127_10054566_2 isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 294.0
DTH2_k127_10054566_3 Biotin carboxylase C-terminal domain K01965,K01968 - 6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000002446 226.0
DTH2_k127_10054566_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000009915 211.0
DTH2_k127_10054566_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000004475 110.0
DTH2_k127_10054566_6 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000008507 76.0
DTH2_k127_10054566_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00001483 47.0
DTH2_k127_1020467_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 338.0
DTH2_k127_1020467_1 Protein of unknown function (DUF2845) - - - 0.000000000000000000000000000004116 127.0
DTH2_k127_1020467_2 - - - - 0.000000000000000000000000000005052 126.0
DTH2_k127_1020467_3 Cupin 2, conserved barrel domain protein - - - 0.00001308 52.0
DTH2_k127_1054649_0 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 7.784e-226 711.0
DTH2_k127_1054649_1 Helix-hairpin-helix motif - - - 0.00000000000000001542 89.0
DTH2_k127_1063948_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 612.0
DTH2_k127_1142540_0 transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 332.0
DTH2_k127_1142540_1 Domain of unknown function (DUF4340) - - - 0.000000001847 69.0
DTH2_k127_116598_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 545.0
DTH2_k127_116598_1 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001346 280.0
DTH2_k127_116598_2 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000008784 213.0
DTH2_k127_116598_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000002571 149.0
DTH2_k127_116598_4 Flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000003068 125.0
DTH2_k127_116598_5 PFAM response regulator receiver - - - 0.000000000000000000000000000044 129.0
DTH2_k127_116598_6 - - - - 0.0000000000000000000008126 105.0
DTH2_k127_116598_7 PFAM MgtE intracellular - - - 0.000000000007852 74.0
DTH2_k127_1187608_0 glycosyl transferase - - - 0.000000000000000000000000000004924 129.0
DTH2_k127_1187608_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000001629 124.0
DTH2_k127_1239939_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004193 273.0
DTH2_k127_1239939_1 photosystem II stabilization K02237,K02238,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000004098 103.0
DTH2_k127_1239939_2 Belongs to the CarB family K01955 - 6.3.5.5 0.00000006605 54.0
DTH2_k127_1279215_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 530.0
DTH2_k127_1279215_1 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000004683 93.0
DTH2_k127_1279215_2 - - - - 0.0000002191 57.0
DTH2_k127_1282197_0 transporter antisigma-factor antagonist STAS K03321 - - 3.529e-200 636.0
DTH2_k127_1282394_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 461.0
DTH2_k127_1282394_1 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000002165 173.0
DTH2_k127_1282394_2 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.0002055 51.0
DTH2_k127_1286974_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.301e-244 790.0
DTH2_k127_1286974_1 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 308.0
DTH2_k127_1286974_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000002888 195.0
DTH2_k127_1286974_3 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000001506 169.0
DTH2_k127_1292078_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 500.0
DTH2_k127_1292078_1 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000136 133.0
DTH2_k127_1292078_2 Histidine kinase - - - 0.000000000000001616 78.0
DTH2_k127_1292078_3 NMT1-like family K02051,K15553 - - 0.0000006674 61.0
DTH2_k127_1292078_4 PFAM Type IV pilus assembly PilZ - - - 0.00000362 54.0
DTH2_k127_1297777_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 321.0
DTH2_k127_1297777_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006027 260.0
DTH2_k127_1297777_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000287 177.0
DTH2_k127_1297777_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000002018 168.0
DTH2_k127_1297777_4 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.00000000000000000001284 95.0
DTH2_k127_1302929_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000115 182.0
DTH2_k127_1302929_1 - - - - 0.0000000000000000000000000000000000000000000001638 172.0
DTH2_k127_1302929_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000002179 174.0
DTH2_k127_1302929_3 - - - - 0.0000000000000000000000002397 106.0
DTH2_k127_1303986_0 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 318.0
DTH2_k127_1303986_1 Thioesterase-like superfamily K07107 - - 0.000000000000000000000001435 113.0
DTH2_k127_1303986_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000001263 77.0
DTH2_k127_1306541_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 512.0
DTH2_k127_1306541_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001646 181.0
DTH2_k127_1306541_2 transporter component K07112 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000003963 57.0
DTH2_k127_1306541_3 Chromate resistance exported protein - - - 0.000002557 51.0
DTH2_k127_1306686_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000001209 231.0
DTH2_k127_1306686_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
DTH2_k127_1306686_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000005895 87.0
DTH2_k127_1314987_0 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 372.0
DTH2_k127_1314987_1 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
DTH2_k127_1314987_2 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000001489 166.0
DTH2_k127_1314987_3 - - - - 0.00001341 53.0
DTH2_k127_1319376_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 286.0
DTH2_k127_1319376_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007007 297.0
DTH2_k127_1319376_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000001086 157.0
DTH2_k127_1319376_3 thiamine biosynthesis protein ThiS K03154 - - 0.000000000009902 69.0
DTH2_k127_1325919_0 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 606.0
DTH2_k127_1325919_1 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 314.0
DTH2_k127_1325919_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 297.0
DTH2_k127_1325919_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 256.0
DTH2_k127_1325919_4 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000001523 233.0
DTH2_k127_1325919_5 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000902 158.0
DTH2_k127_1325919_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000002034 155.0
DTH2_k127_1325919_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000007326 126.0
DTH2_k127_1325919_8 peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000002288 125.0
DTH2_k127_1325919_9 PFAM response regulator receiver K07666 - - 0.000000000000001917 81.0
DTH2_k127_1336770_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
DTH2_k127_1336770_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000004924 190.0
DTH2_k127_1336770_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000002835 164.0
DTH2_k127_1336770_3 LysM domain - - - 0.00000000000000000000000000000007458 137.0
DTH2_k127_1336770_4 Peptidase family M23 - - - 0.0000000000000000000007445 97.0
DTH2_k127_1339836_0 PFAM DAHP synthetase I K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 432.0
DTH2_k127_1339836_1 NUDIX domain K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 373.0
DTH2_k127_1343571_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 438.0
DTH2_k127_1343571_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000248 201.0
DTH2_k127_1343571_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000003145 121.0
DTH2_k127_1366694_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 307.0
DTH2_k127_1366694_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000007257 249.0
DTH2_k127_1376985_0 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000003401 172.0
DTH2_k127_1376985_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000007575 169.0
DTH2_k127_1376985_2 AI-2E family transporter - - - 0.00000000000000000000000000000002823 140.0
DTH2_k127_1376985_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000008993 100.0
DTH2_k127_1376985_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000002661 83.0
DTH2_k127_1376985_5 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000008016 81.0
DTH2_k127_1376985_6 PBS lyase HEAT-like repeat - - - 0.00000000004925 74.0
DTH2_k127_1396291_0 Conserved region in glutamate synthase - - - 1.212e-295 913.0
DTH2_k127_1396291_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 568.0
DTH2_k127_1396291_2 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 427.0
DTH2_k127_1396291_3 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 384.0
DTH2_k127_1396291_4 NAD binding K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 360.0
DTH2_k127_1396291_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 307.0
DTH2_k127_1396291_6 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000001627 178.0
DTH2_k127_1396291_7 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000001416 138.0
DTH2_k127_1405694_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 400.0
DTH2_k127_1405694_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000008069 147.0
DTH2_k127_1423543_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000687 270.0
DTH2_k127_1423543_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000046 264.0
DTH2_k127_1427976_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000001516 195.0
DTH2_k127_1427976_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000007049 125.0
DTH2_k127_1435170_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 531.0
DTH2_k127_1435170_1 belongs to the CobB CobQ family K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000007405 183.0
DTH2_k127_1435170_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000000000000004188 169.0
DTH2_k127_1448617_0 UPF0210 protein K09157 - - 0.000000000000000000000000000000000000000000000004024 174.0
DTH2_k127_1448617_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000001043 154.0
DTH2_k127_1448617_2 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000001457 111.0
DTH2_k127_1448617_3 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000001666 116.0
DTH2_k127_1477504_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 445.0
DTH2_k127_1477504_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000002278 202.0
DTH2_k127_1477504_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000003429 132.0
DTH2_k127_1477504_3 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000006589 130.0
DTH2_k127_1481913_0 PFAM peptidase C14, caspase catalytic - - - 0.0000000000000000007464 88.0
DTH2_k127_1481913_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000001839 70.0
DTH2_k127_1481913_2 self proteolysis - - - 0.000000000003552 79.0
DTH2_k127_1521263_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 290.0
DTH2_k127_1521263_1 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000001011 200.0
DTH2_k127_1528567_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 558.0
DTH2_k127_1528567_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001075 245.0
DTH2_k127_1528567_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000004277 88.0
DTH2_k127_1528567_3 NMT1-like family K02051 - - 0.00007088 48.0
DTH2_k127_1531236_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 524.0
DTH2_k127_1531236_1 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.0000000000000000000000000000000000000000000000000002235 191.0
DTH2_k127_1531705_0 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000003159 158.0
DTH2_k127_1531705_1 Cytidylate kinase-like family - - - 0.000000000000000000000002659 112.0
DTH2_k127_1531705_2 Translation Initiation Factor K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001961 103.0
DTH2_k127_1531705_3 Protein of unknown function (DUF2914) - - - 0.0000000000003862 74.0
DTH2_k127_1531705_4 Protein of unknown function (DUF1573) - - - 0.00006235 51.0
DTH2_k127_1542041_0 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 333.0
DTH2_k127_1542041_1 - - - - 0.0000000000000000000000000000000003071 144.0
DTH2_k127_1542041_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000001476 137.0
DTH2_k127_1551402_0 Response receiver scaffold protein CheV K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 330.0
DTH2_k127_1551402_1 Histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005509 280.0
DTH2_k127_1551402_2 self proteolysis - - - 0.000000004845 69.0
DTH2_k127_1551402_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0005938 46.0
DTH2_k127_1559221_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 319.0
DTH2_k127_1559221_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000001993 209.0
DTH2_k127_1559221_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000001523 69.0
DTH2_k127_1576402_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.131e-208 653.0
DTH2_k127_1576402_1 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 320.0
DTH2_k127_1576402_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000001306 158.0
DTH2_k127_158868_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 374.0
DTH2_k127_158868_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 298.0
DTH2_k127_158868_2 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000001066 78.0
DTH2_k127_158868_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000001316 64.0
DTH2_k127_158868_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0006339 46.0
DTH2_k127_1601890_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 497.0
DTH2_k127_1601890_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 309.0
DTH2_k127_1601890_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000863 262.0
DTH2_k127_1601890_3 Universal stress protein family - - - 0.000000000000000000000000000001065 127.0
DTH2_k127_1601890_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000004142 93.0
DTH2_k127_1601890_5 -acetyltransferase - - - 0.0001792 48.0
DTH2_k127_1631268_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 447.0
DTH2_k127_1631268_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 356.0
DTH2_k127_1631268_2 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000002356 223.0
DTH2_k127_1631268_3 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.000000000000000000000000000000000000000000006884 164.0
DTH2_k127_1631268_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000001242 79.0
DTH2_k127_1648961_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001452 289.0
DTH2_k127_1648961_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000009462 125.0
DTH2_k127_1648961_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00001663 48.0
DTH2_k127_1649324_0 CARDB domain-containing protein,subtilase family protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 479.0
DTH2_k127_1649324_1 Large extracellular alpha-helical protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 356.0
DTH2_k127_1649324_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 292.0
DTH2_k127_1652249_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 436.0
DTH2_k127_1652249_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 388.0
DTH2_k127_1652249_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 336.0
DTH2_k127_1652249_3 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000002644 179.0
DTH2_k127_1652249_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000006992 103.0
DTH2_k127_1680352_0 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 453.0
DTH2_k127_1680352_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 304.0
DTH2_k127_1680352_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000001339 166.0
DTH2_k127_1680352_3 Aldo/keto reductase family - - - 0.0000000000000001237 81.0
DTH2_k127_1694273_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 566.0
DTH2_k127_1694273_1 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000002829 113.0
DTH2_k127_1699186_0 Metal dependent phosphohydrolase - - - 0.0000000000000000000000000000002748 124.0
DTH2_k127_1699186_1 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000001939 131.0
DTH2_k127_1709225_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 550.0
DTH2_k127_1709225_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 472.0
DTH2_k127_1709225_2 ATPases associated with a variety of cellular activities K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001999 252.0
DTH2_k127_1709225_3 - - - - 0.000000000000000000000000000000000000000005111 158.0
DTH2_k127_1709225_4 hydroperoxide reductase activity - - - 0.000000000000000000000002387 105.0
DTH2_k127_1709225_5 Cupin 2, conserved barrel domain protein - - - 0.00000000008752 65.0
DTH2_k127_1709225_6 PFAM Integral membrane protein TerC K05794 - - 0.00000002815 55.0
DTH2_k127_1709225_8 carboxymuconolactone decarboxylase K07486 - - 0.0002532 48.0
DTH2_k127_1715997_0 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 481.0
DTH2_k127_1736488_0 Sugar (and other) transporter K03446 - - 1.134e-197 628.0
DTH2_k127_1736488_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007612 257.0
DTH2_k127_1736488_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
DTH2_k127_1736488_3 PFAM doubled CXXCH domain protein - - - 0.00000000000000000000000000000000000000000000000000000000007527 216.0
DTH2_k127_1736488_4 denitrification pathway - - - 0.00001147 49.0
DTH2_k127_1741381_0 response regulator K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007787 279.0
DTH2_k127_1741381_1 helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
DTH2_k127_1751909_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 365.0
DTH2_k127_1751909_1 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007964 287.0
DTH2_k127_1751909_2 aminotransferase K00813,K00832 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000009104 226.0
DTH2_k127_1751909_3 4Fe-4S binding domain - - - 0.000000000000000000000000000004634 121.0
DTH2_k127_1759722_0 SNF2 Helicase protein - - - 3.952e-297 925.0
DTH2_k127_1759722_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 407.0
DTH2_k127_181367_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 417.0
DTH2_k127_181367_1 Belongs to the MurCDEF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 323.0
DTH2_k127_181367_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 308.0
DTH2_k127_181367_3 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000001824 222.0
DTH2_k127_181367_4 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000001964 180.0
DTH2_k127_181367_5 metalloendopeptidase activity - - - 0.00000000000000000000000000006511 128.0
DTH2_k127_1854028_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 298.0
DTH2_k127_1854028_1 Bacterial extracellular solute-binding protein K10938 - - 0.0000000000000000000000000000000000000000000000000001016 197.0
DTH2_k127_1854028_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000002354 137.0
DTH2_k127_1854028_3 Prokaryotic diacylglycerol kinase - - - 0.00000000000000000000002529 100.0
DTH2_k127_1854028_4 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000002166 73.0
DTH2_k127_1857119_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000004091 244.0
DTH2_k127_1857119_1 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000000000000005736 89.0
DTH2_k127_1885799_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 366.0
DTH2_k127_1885799_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000003039 168.0
DTH2_k127_1885799_2 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000124 130.0
DTH2_k127_1885799_3 Glyceraldehyde 3-phosphate dehydrogenase, glycosomal K00134 - 1.2.1.12 0.0000000000000000000000000000009804 122.0
DTH2_k127_1885799_4 Sulfatase K01130 - 3.1.6.1 0.0000000001443 63.0
DTH2_k127_1885799_5 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000002467 50.0
DTH2_k127_1885799_6 - - - - 0.000393 48.0
DTH2_k127_1964554_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 403.0
DTH2_k127_1964554_1 Short-chain dehydrogenase reductase sdr - - - 0.00000008984 57.0
DTH2_k127_1984920_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 535.0
DTH2_k127_1984920_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 315.0
DTH2_k127_1984920_10 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000002471 152.0
DTH2_k127_1984920_11 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000003977 135.0
DTH2_k127_1984920_12 Glutathione peroxidase - - - 0.000000000000000000000000000009462 125.0
DTH2_k127_1984920_13 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000002168 112.0
DTH2_k127_1984920_14 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000003664 100.0
DTH2_k127_1984920_15 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0002999 44.0
DTH2_k127_1984920_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 317.0
DTH2_k127_1984920_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 293.0
DTH2_k127_1984920_4 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000001176 213.0
DTH2_k127_1984920_5 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000009065 211.0
DTH2_k127_1984920_6 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001043 210.0
DTH2_k127_1984920_7 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000579 203.0
DTH2_k127_1984920_8 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000001704 169.0
DTH2_k127_1984920_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000003401 157.0
DTH2_k127_1989197_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000002207 264.0
DTH2_k127_1989197_1 signal transduction histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001642 213.0
DTH2_k127_1989197_2 domain protein - - - 0.000005563 50.0
DTH2_k127_200759_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 372.0
DTH2_k127_200759_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000002254 119.0
DTH2_k127_2027237_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002877 278.0
DTH2_k127_2027237_1 Protein conserved in bacteria K09939 - - 0.00000000000000000000000000000000000000000000005974 175.0
DTH2_k127_2071563_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 448.0
DTH2_k127_2071563_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001351 248.0
DTH2_k127_2071563_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000005506 175.0
DTH2_k127_2094785_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 458.0
DTH2_k127_2094785_1 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002911 253.0
DTH2_k127_2094785_2 trans-aconitate 2-methyltransferase activity K00598,K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0030798,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704 2.1.1.144,2.1.1.197 0.00000000000000000000006392 99.0
DTH2_k127_2094785_3 Methyltransferase domain K00598 - 2.1.1.144 0.0000000000000001064 80.0
DTH2_k127_2124269_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 286.0
DTH2_k127_2124269_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000003893 72.0
DTH2_k127_2124269_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0003642 52.0
DTH2_k127_2124269_4 COG0457 FOG TPR repeat - - - 0.0006387 51.0
DTH2_k127_2153895_0 Belongs to the ompA family - - - 3.988e-238 759.0
DTH2_k127_2153895_1 Predicted membrane protein (DUF2254) - - - 0.0000000000009318 70.0
DTH2_k127_220589_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 291.0
DTH2_k127_220589_1 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001113 274.0
DTH2_k127_220589_2 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
DTH2_k127_220589_3 Cytochrome C' - - - 0.0002073 50.0
DTH2_k127_2216139_0 PFAM Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 527.0
DTH2_k127_2216139_1 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000000001121 178.0
DTH2_k127_2216139_2 actin binding - - - 0.00000000000000000000000000000000000000000001274 165.0
DTH2_k127_2216139_3 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000000000837 154.0
DTH2_k127_2216139_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000003236 138.0
DTH2_k127_2216139_5 Histidine kinase K02660,K11525 - - 0.00000000000000000000066 107.0
DTH2_k127_2216139_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000009972 85.0
DTH2_k127_2226360_0 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000003905 153.0
DTH2_k127_2226360_1 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000001052 147.0
DTH2_k127_2226360_2 Glycosyltransferase Family 4 - - - 0.00000000003684 66.0
DTH2_k127_2226360_3 Acyltransferase family - - - 0.0003976 51.0
DTH2_k127_2285664_0 - K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000469 287.0
DTH2_k127_2285664_1 Tetratricopeptide repeat - - - 0.00004131 49.0
DTH2_k127_2307593_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.085e-222 698.0
DTH2_k127_2307593_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 302.0
DTH2_k127_2387911_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 503.0
DTH2_k127_2387911_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 366.0
DTH2_k127_2387911_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 304.0
DTH2_k127_2387911_3 lipoprotein Blc K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000002078 230.0
DTH2_k127_241616_0 - K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 435.0
DTH2_k127_241616_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000628 260.0
DTH2_k127_241616_2 NLP P60 protein - - - 0.00000000000000000000000000000000000000000001461 170.0
DTH2_k127_241616_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000006058 51.0
DTH2_k127_2424325_0 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 450.0
DTH2_k127_2424325_1 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000004376 213.0
DTH2_k127_2426160_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 289.0
DTH2_k127_2426160_1 Peptidoglycan glycosyltransferase K08384 - - 0.0000000000000000000000000000000000000000000544 173.0
DTH2_k127_2474618_0 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 385.0
DTH2_k127_2474618_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000121 282.0
DTH2_k127_2531807_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 512.0
DTH2_k127_2531807_1 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 315.0
DTH2_k127_2534709_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 524.0
DTH2_k127_2534709_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 321.0
DTH2_k127_2534709_2 Bacterial type II and III secretion system protein K12282 - - 0.000000000000000000000000000000000000000000002903 170.0
DTH2_k127_2534709_3 - K02450 - - 0.0002814 53.0
DTH2_k127_2536267_0 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001 240.0
DTH2_k127_2536267_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000001947 243.0
DTH2_k127_2536267_2 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000002223 177.0
DTH2_k127_2539154_0 PFAM glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 461.0
DTH2_k127_2539154_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 376.0
DTH2_k127_2548773_0 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000001337 233.0
DTH2_k127_2548773_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000238 162.0
DTH2_k127_2548773_2 - - - - 0.0000000000000000000000000000000000000006341 152.0
DTH2_k127_2548773_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000001058 56.0
DTH2_k127_2550775_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 429.0
DTH2_k127_2550775_1 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000009338 175.0
DTH2_k127_2556736_0 Elongation factor SelB, winged helix K03833 - - 6.219e-204 654.0
DTH2_k127_2556736_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 502.0
DTH2_k127_2556736_2 cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 478.0
DTH2_k127_2556736_3 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 360.0
DTH2_k127_2556736_4 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000001783 220.0
DTH2_k127_2556736_5 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000001384 172.0
DTH2_k127_2556736_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000457 112.0
DTH2_k127_2560212_0 organic phosphonate transport K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000001116 237.0
DTH2_k127_2560212_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000003719 235.0
DTH2_k127_2560212_2 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000005285 175.0
DTH2_k127_2601979_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000007489 260.0
DTH2_k127_2601979_1 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
DTH2_k127_2601979_2 Fe-S cluster K04488 - - 0.0000000000000000000000000000000000000000000000001692 182.0
DTH2_k127_2610041_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 542.0
DTH2_k127_2610041_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 344.0
DTH2_k127_2610041_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000002242 218.0
DTH2_k127_2613882_0 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 554.0
DTH2_k127_2618199_0 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 556.0
DTH2_k127_2618199_1 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 298.0
DTH2_k127_2621972_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00394 - 1.8.99.2 1.465e-308 956.0
DTH2_k127_2621972_1 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 391.0
DTH2_k127_2621972_2 reductase, beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000006843 221.0
DTH2_k127_2621972_3 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000008503 202.0
DTH2_k127_2623784_0 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 303.0
DTH2_k127_2623784_1 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000001424 197.0
DTH2_k127_2623784_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000002651 182.0
DTH2_k127_2623784_3 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000000002744 102.0
DTH2_k127_2623784_4 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000009947 88.0
DTH2_k127_2625882_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 587.0
DTH2_k127_2625882_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 287.0
DTH2_k127_2625882_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
DTH2_k127_2625882_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002123 215.0
DTH2_k127_2625882_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000004609 59.0
DTH2_k127_2634016_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 4.462e-203 642.0
DTH2_k127_2634016_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000004981 127.0
DTH2_k127_2634016_2 Lipopolysaccharide-assembly - - - 0.0000004372 59.0
DTH2_k127_2634016_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00001817 50.0
DTH2_k127_2639085_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003497 272.0
DTH2_k127_2639085_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003229 275.0
DTH2_k127_2639085_2 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000008572 140.0
DTH2_k127_2639085_3 - - - - 0.000000000000000000000000000000009822 135.0
DTH2_k127_2639085_4 - - - - 0.00000000000000000000000002057 110.0
DTH2_k127_2639085_5 SMART Transport-associated and nodulation region - - - 0.0000000000000000000000008546 109.0
DTH2_k127_2639085_6 - - - - 0.0000000000000004295 78.0
DTH2_k127_2639085_7 cellulase activity K01183,K01728 - 3.2.1.14,4.2.2.2 0.0001622 48.0
DTH2_k127_2639085_8 - - - - 0.0004719 48.0
DTH2_k127_2641489_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 8.407e-220 702.0
DTH2_k127_2641489_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
DTH2_k127_2641489_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 365.0
DTH2_k127_2641489_3 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 375.0
DTH2_k127_2641489_4 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
DTH2_k127_2641489_5 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000000001082 220.0
DTH2_k127_2641489_6 Response regulator receiver domain K03413 - - 0.00000000000000000000002553 99.0
DTH2_k127_2641489_7 STAS domain - - - 0.0000000000001814 76.0
DTH2_k127_2641489_8 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000006811 60.0
DTH2_k127_2641489_9 NosL - - - 0.0009029 50.0
DTH2_k127_2660897_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 365.0
DTH2_k127_2660897_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 294.0
DTH2_k127_2660897_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000002879 199.0
DTH2_k127_2660897_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000001848 190.0
DTH2_k127_2660897_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000005122 194.0
DTH2_k127_2660897_5 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000003006 183.0
DTH2_k127_2663396_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 4.978e-264 831.0
DTH2_k127_2663396_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 530.0
DTH2_k127_2663396_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 383.0
DTH2_k127_2663396_3 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003186 264.0
DTH2_k127_2663396_4 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000487 183.0
DTH2_k127_2663396_5 Fis family transcriptional regulator - - - 0.0000000000000000000000000000000002587 142.0
DTH2_k127_2668102_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.124e-197 621.0
DTH2_k127_2668102_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000003573 233.0
DTH2_k127_2668102_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000009226 233.0
DTH2_k127_2668102_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000009922 68.0
DTH2_k127_2683708_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 288.0
DTH2_k127_2683708_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000009924 201.0
DTH2_k127_2683708_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000002733 94.0
DTH2_k127_2683708_3 Sulfur reduction protein DsrE - - - 0.00000009256 58.0
DTH2_k127_2691315_0 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 545.0
DTH2_k127_2691315_1 PFAM cytochrome c, class I K08738 - - 0.00000000006104 66.0
DTH2_k127_2693114_0 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002021 287.0
DTH2_k127_2693114_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000001817 151.0
DTH2_k127_2694762_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 366.0
DTH2_k127_2694762_1 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000001001 133.0
DTH2_k127_2694762_2 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000002678 122.0
DTH2_k127_2694762_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000001005 69.0
DTH2_k127_270175_0 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 425.0
DTH2_k127_270175_1 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000001797 148.0
DTH2_k127_2705590_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 9.669e-293 908.0
DTH2_k127_2705590_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 4.856e-248 780.0
DTH2_k127_2705590_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 393.0
DTH2_k127_2705590_3 - - - - 0.0000000000001675 72.0
DTH2_k127_2706199_0 Histidine kinase K07637 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 380.0
DTH2_k127_2706199_1 response regulator receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 325.0
DTH2_k127_2706199_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006564 251.0
DTH2_k127_2706199_3 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000001296 108.0
DTH2_k127_2706199_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000001667 58.0
DTH2_k127_2706199_5 Peptidase propeptide and YPEB domain - - - 0.0001367 48.0
DTH2_k127_271023_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 562.0
DTH2_k127_271023_1 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000426 146.0
DTH2_k127_2737146_0 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 544.0
DTH2_k127_2737146_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003558 237.0
DTH2_k127_2743431_0 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000001067 153.0
DTH2_k127_2743431_1 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000007544 110.0
DTH2_k127_2750676_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 323.0
DTH2_k127_2750676_1 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.00000000000000000000000000000000000231 138.0
DTH2_k127_2750676_2 ThiF family - - - 0.0000000000000002222 79.0
DTH2_k127_2757955_0 Glycosyltransferase family 92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001215 279.0
DTH2_k127_2757955_1 Capsule polysaccharide biosynthesis protein K07265 - - 0.000000000000000000000000000000000000000000000000000000000005464 224.0
DTH2_k127_2757955_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000006205 148.0
DTH2_k127_2757955_3 Glycosyltransferases involved in cell wall biogenesis K16556 - - 0.000000000000000000000000000000000004753 150.0
DTH2_k127_2757955_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000006371 140.0
DTH2_k127_2757955_5 Sulfotransferase family - - - 0.00000000000003709 79.0
DTH2_k127_2757955_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000002397 63.0
DTH2_k127_2761258_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 549.0
DTH2_k127_2761258_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000002289 207.0
DTH2_k127_2761258_2 Belongs to the UPF0434 family K09791 - - 0.000000000000000007262 85.0
DTH2_k127_2761870_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 564.0
DTH2_k127_2761870_1 Gram-negative-bacterium-type cell wall biogenesis - GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000001136 88.0
DTH2_k127_2786133_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002127 279.0
DTH2_k127_2792496_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 546.0
DTH2_k127_2792496_1 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
DTH2_k127_2792496_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000007439 138.0
DTH2_k127_2807765_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 561.0
DTH2_k127_2807765_1 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 411.0
DTH2_k127_2807765_10 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000001665 77.0
DTH2_k127_2807765_11 PFAM Prenyltransferase squalene oxidase K01077,K11751 - 3.1.3.1,3.1.3.5,3.6.1.45 0.00000000005399 76.0
DTH2_k127_2807765_12 Exporters of the RND superfamily K07003 - - 0.00001817 50.0
DTH2_k127_2807765_2 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 394.0
DTH2_k127_2807765_3 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 314.0
DTH2_k127_2807765_4 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000000000000000000000000000001135 207.0
DTH2_k127_2807765_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000007698 185.0
DTH2_k127_2807765_6 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000001443 169.0
DTH2_k127_2807765_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000114 165.0
DTH2_k127_2807765_8 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000005963 131.0
DTH2_k127_2807765_9 PKD domain - - - 0.0000000000000001908 94.0
DTH2_k127_2830552_0 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 462.0
DTH2_k127_2830552_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 338.0
DTH2_k127_2830552_2 COG1233 Phytoene dehydrogenase and related proteins K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.0000000000000000000000000009255 128.0
DTH2_k127_2830552_3 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000001115 100.0
DTH2_k127_2830552_4 methyl-accepting chemotaxis protein K03406 - - 0.00000000002648 70.0
DTH2_k127_2845030_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 508.0
DTH2_k127_2845030_1 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000001611 219.0
DTH2_k127_2845030_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000004509 186.0
DTH2_k127_2903707_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 4.031e-256 800.0
DTH2_k127_2903707_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 548.0
DTH2_k127_2903707_10 4Fe-4S binding domain - - - 0.000002467 50.0
DTH2_k127_2903707_2 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001572 266.0
DTH2_k127_2903707_3 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000007783 128.0
DTH2_k127_2903707_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000005277 119.0
DTH2_k127_2903707_5 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000002205 104.0
DTH2_k127_2903707_6 - - - - 0.0000000000000000001179 94.0
DTH2_k127_2903707_7 Domain of unknown function (DUF1858) - - - 0.0000000000000000004803 91.0
DTH2_k127_2903707_8 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000005298 92.0
DTH2_k127_2903707_9 PFAM Type IV pilus assembly PilZ - - - 0.0000000003303 64.0
DTH2_k127_2912759_0 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000004436 208.0
DTH2_k127_2912759_1 nickel cation binding K04651,K19640 - - 0.000000000000000000000002946 106.0
DTH2_k127_2912759_2 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000003101 98.0
DTH2_k127_2912759_3 response regulator K07712 - - 0.0000000000009776 70.0
DTH2_k127_2936157_0 flavodoxin nitric oxide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 410.0
DTH2_k127_2936157_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000007522 234.0
DTH2_k127_2936157_2 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000005847 101.0
DTH2_k127_2936157_3 Protein of unknown function (DUF465) K09794 - - 0.000000000000002943 80.0
DTH2_k127_2936157_4 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP-binding K00158 - 1.2.3.3 0.000000000000649 68.0
DTH2_k127_3025270_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 546.0
DTH2_k127_3025270_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 407.0
DTH2_k127_3025270_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 307.0
DTH2_k127_3025270_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001801 271.0
DTH2_k127_3025270_4 Cytochrome b/b6/petB K03887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002972 263.0
DTH2_k127_3025270_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000002005 204.0
DTH2_k127_3025270_6 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000001081 101.0
DTH2_k127_3025270_7 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000001479 98.0
DTH2_k127_3044492_0 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002755 239.0
DTH2_k127_3044492_1 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000002595 228.0
DTH2_k127_3044492_2 PFAM SOUL haem-binding protein - - - 0.000000000000000000000000000000000000000000002419 172.0
DTH2_k127_3044492_3 Pfam:Pyridox_oxidase - - - 0.000002126 54.0
DTH2_k127_304969_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 547.0
DTH2_k127_304969_1 Chemoreceptor zinc-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 353.0
DTH2_k127_304969_10 Oxygen tolerance - - - 0.0002035 46.0
DTH2_k127_304969_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 320.0
DTH2_k127_304969_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001159 289.0
DTH2_k127_304969_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003638 247.0
DTH2_k127_304969_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis - - - 0.0000000000000000000000000000000000000000000000005411 182.0
DTH2_k127_304969_6 signal transduction histidine kinase - - - 0.0000000000000000000000000000002981 144.0
DTH2_k127_304969_7 Response regulator receiver - - - 0.000000000000000000002934 98.0
DTH2_k127_304969_8 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000002054 99.0
DTH2_k127_304969_9 HAMP domain - - - 0.0000000000000000002141 105.0
DTH2_k127_3104457_0 Bacterial protein of unknown function (DUF853) K06915 - - 9.632e-206 651.0
DTH2_k127_3104457_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000003256 234.0
DTH2_k127_3104457_2 Water Stress and Hypersensitive response - - - 0.00000000000000000000000000000000000000000000000000000397 197.0
DTH2_k127_3104457_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000001387 120.0
DTH2_k127_3104457_4 Mediates influx of magnesium ions K03284 - - 0.00000000000000004178 80.0
DTH2_k127_3107633_0 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 532.0
DTH2_k127_3107633_1 - - - - 0.00000000000000000000000004994 111.0
DTH2_k127_3107633_2 InterPro IPR007367 - - - 0.0000000000000000000001166 100.0
DTH2_k127_3107633_3 related to archaeal Holliday junction resolvase - - - 0.0002209 47.0
DTH2_k127_3107633_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0006429 45.0
DTH2_k127_3108040_0 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000009423 256.0
DTH2_k127_3108040_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000001527 168.0
DTH2_k127_3108040_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000002206 97.0
DTH2_k127_3113673_0 Flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 332.0
DTH2_k127_3113673_1 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000167 253.0
DTH2_k127_3113673_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 GO:0003674,GO:0003824,GO:0008808,GO:0016740,GO:0016772,GO:0016780,GO:0030572 - 0.00000000000000000000000000000000000001654 153.0
DTH2_k127_3113673_3 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.0000000000000000000000000000000002469 134.0
DTH2_k127_3113673_4 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000007717 116.0
DTH2_k127_3113673_5 - - - - 0.000000000000000000007535 107.0
DTH2_k127_3113673_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000006483 96.0
DTH2_k127_3113673_7 Role in flagellar biosynthesis K02420 - - 0.000000000000000001563 89.0
DTH2_k127_3113673_8 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000008642 52.0
DTH2_k127_3113673_9 PFAM Flagellar biosynthesis protein, FliO K02418 - - 0.0009325 46.0
DTH2_k127_312399_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206,K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000002088 183.0
DTH2_k127_312399_1 permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000003229 127.0
DTH2_k127_312399_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000003711 92.0
DTH2_k127_312399_3 Permease YjgP YjgQ family protein K07091,K11720 - - 0.000000000654 62.0
DTH2_k127_3133442_0 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 332.0
DTH2_k127_3133442_1 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000003512 161.0
DTH2_k127_3133442_2 heat shock protein binding - - - 0.0000000000000811 78.0
DTH2_k127_3133442_3 General secretion pathway protein h K02457 - - 0.0000001157 62.0
DTH2_k127_314664_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000002047 182.0
DTH2_k127_314664_1 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000437 184.0
DTH2_k127_314664_2 methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000005118 167.0
DTH2_k127_3173067_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 3.842e-287 905.0
DTH2_k127_3173067_1 Aminotransferase class-III K01845 - 5.4.3.8 2.251e-201 635.0
DTH2_k127_3173067_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 569.0
DTH2_k127_3173067_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000004962 206.0
DTH2_k127_3173067_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000003714 174.0
DTH2_k127_3173067_5 - - - - 0.00000000000000000000000000006824 121.0
DTH2_k127_3173067_6 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000764 107.0
DTH2_k127_3180449_0 COG0058 Glucan phosphorylase - - - 7.381e-258 805.0
DTH2_k127_3180449_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 306.0
DTH2_k127_3180449_2 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000002087 224.0
DTH2_k127_3180449_3 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000007736 54.0
DTH2_k127_3197348_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 4.125e-236 746.0
DTH2_k127_3197348_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 425.0
DTH2_k127_3197348_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000009496 120.0
DTH2_k127_3197348_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000003196 50.0
DTH2_k127_3217418_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000007427 244.0
DTH2_k127_3217418_1 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000008729 177.0
DTH2_k127_3217418_2 - - - - 0.0000000000000000000000000000005669 128.0
DTH2_k127_3220881_0 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 361.0
DTH2_k127_3220881_1 HlyD membrane-fusion protein of T1SS K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 285.0
DTH2_k127_3220881_2 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000001322 151.0
DTH2_k127_3220881_3 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000003908 110.0
DTH2_k127_3220881_4 - - - - 0.00004946 55.0
DTH2_k127_3229399_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1478.0
DTH2_k127_3229399_1 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 467.0
DTH2_k127_3229399_2 - - - - 0.0000009638 58.0
DTH2_k127_323146_0 NAD dependent epimerase dehydratase family K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 484.0
DTH2_k127_323146_1 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 285.0
DTH2_k127_323146_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.00000000000000000000000000000000000000000000374 166.0
DTH2_k127_325882_0 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 1.677e-235 748.0
DTH2_k127_325882_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 544.0
DTH2_k127_325882_2 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004878 254.0
DTH2_k127_3306399_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 412.0
DTH2_k127_3306399_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000007016 232.0
DTH2_k127_3329072_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 365.0
DTH2_k127_339170_0 Peptidase M16C associated K06972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 324.0
DTH2_k127_339170_1 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000005438 214.0
DTH2_k127_339170_2 Single cache domain 3 K03406 - - 0.00000000000000000000000000000000000000000001029 179.0
DTH2_k127_342375_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 393.0
DTH2_k127_342375_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 328.0
DTH2_k127_342375_2 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 312.0
DTH2_k127_342375_3 Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates K08722 GO:0002953,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0010139,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032262,GO:0034641,GO:0034654,GO:0042578,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046078,GO:0046385,GO:0046483,GO:0046872,GO:0046914,GO:0050897,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.89 0.000000000000000000000000000000000000000000000000000000000000000397 227.0
DTH2_k127_348191_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 327.0
DTH2_k127_348191_1 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000002669 197.0
DTH2_k127_348191_2 COG2863 Cytochrome c553 - - - 0.000000000000000000000006721 105.0
DTH2_k127_348205_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 487.0
DTH2_k127_348205_1 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 362.0
DTH2_k127_348205_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 354.0
DTH2_k127_348205_3 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006143 248.0
DTH2_k127_348205_4 RNA pseudouridylate synthase - - - 0.000000000000000000000000000000000000000000000000000000009599 209.0
DTH2_k127_3500809_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.968e-320 996.0
DTH2_k127_3500809_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000002006 208.0
DTH2_k127_3530169_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 593.0
DTH2_k127_3569486_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.379e-244 762.0
DTH2_k127_3569486_1 TIGRFAM SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000002143 205.0
DTH2_k127_3590466_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 523.0
DTH2_k127_3590466_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 384.0
DTH2_k127_3590466_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 338.0
DTH2_k127_3668821_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000007733 216.0
DTH2_k127_3668821_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000001279 178.0
DTH2_k127_3668821_2 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000003416 144.0
DTH2_k127_3687757_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000003332 218.0
DTH2_k127_3687757_1 Protein of unknown function (DUF3124) - - - 0.000000000000000000000000000000000000001148 157.0
DTH2_k127_3687757_2 Lipocalin-like domain - - - 0.0000000000000000000000000000001328 130.0
DTH2_k127_370897_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004641 269.0
DTH2_k127_3795786_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 517.0
DTH2_k127_3795786_1 glucose-6-phosphate isomerase activity K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005982,GO:0006073,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009909,GO:0009911,GO:0009941,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0031967,GO:0031975,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048518,GO:0048580,GO:0048582,GO:0048831,GO:0050789,GO:0050793,GO:0051094,GO:0051239,GO:0051240,GO:0065007,GO:0071704,GO:2000026,GO:2000241,GO:2000243 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 435.0
DTH2_k127_3795786_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 428.0
DTH2_k127_3795786_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 286.0
DTH2_k127_3796082_0 Oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 530.0
DTH2_k127_3796082_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000254 263.0
DTH2_k127_3799865_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 393.0
DTH2_k127_3799865_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 387.0
DTH2_k127_3799865_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 397.0
DTH2_k127_3799865_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 346.0
DTH2_k127_3799865_4 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004776 243.0
DTH2_k127_3799865_5 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000001341 212.0
DTH2_k127_3799865_6 Histidine kinase K13040 - 2.7.13.3 0.000000000000000000000000000000000000000004108 180.0
DTH2_k127_3801584_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 9.385e-209 663.0
DTH2_k127_3805412_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 352.0
DTH2_k127_3805412_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 322.0
DTH2_k127_3805412_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004343 267.0
DTH2_k127_3805412_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000007642 161.0
DTH2_k127_3805412_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000001123 131.0
DTH2_k127_3805412_5 TfoX N-terminal domain - - - 0.000000000000000000000000002125 115.0
DTH2_k127_3805412_6 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000439 115.0
DTH2_k127_3805412_7 cytochrome C peroxidase - - - 0.000000000000000003762 88.0
DTH2_k127_3805412_8 heme-binding sites - - - 0.000000000000005172 77.0
DTH2_k127_3822698_0 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 467.0
DTH2_k127_3822698_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008086 265.0
DTH2_k127_3822698_2 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000001042 144.0
DTH2_k127_3830684_0 General secretory system II, protein E domain protein K02454 - - 3.236e-217 690.0
DTH2_k127_3830684_1 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005541 273.0
DTH2_k127_3830684_2 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009051 248.0
DTH2_k127_3843069_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 3.153e-271 857.0
DTH2_k127_3843069_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000001042 136.0
DTH2_k127_3851233_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 3.981e-202 640.0
DTH2_k127_3851233_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 419.0
DTH2_k127_3851233_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 319.0
DTH2_k127_3851233_3 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 311.0
DTH2_k127_3851233_4 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 298.0
DTH2_k127_3851233_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008307 259.0
DTH2_k127_3851233_6 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000002577 150.0
DTH2_k127_3860334_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 476.0
DTH2_k127_3860334_1 6-phosphofructokinase activity K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 451.0
DTH2_k127_3860334_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000007752 256.0
DTH2_k127_3860334_3 PFAM Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000001979 192.0
DTH2_k127_3860334_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000002093 86.0
DTH2_k127_3860334_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000003583 49.0
DTH2_k127_3884146_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 1.232e-226 732.0
DTH2_k127_3884146_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 378.0
DTH2_k127_3884146_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000002737 81.0
DTH2_k127_3885701_0 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007481 288.0
DTH2_k127_3885701_1 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004914 237.0
DTH2_k127_3885701_2 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.0000000000002026 73.0
DTH2_k127_3897062_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 546.0
DTH2_k127_3897062_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 413.0
DTH2_k127_3897062_2 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 323.0
DTH2_k127_3897062_3 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000706 180.0
DTH2_k127_3897062_4 Flagellar Motor Protein K02557 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009288,GO:0009425,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0071944,GO:0120100,GO:0120101 - 0.0000000000000000000000000000002393 129.0
DTH2_k127_3897062_5 PilZ domain - - - 0.0000000000004224 78.0
DTH2_k127_3923179_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 1.515e-294 915.0
DTH2_k127_3923179_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 3.497e-257 804.0
DTH2_k127_3923179_2 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000002203 196.0
DTH2_k127_3946909_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000002478 253.0
DTH2_k127_3946909_1 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000002135 214.0
DTH2_k127_3946909_2 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000002577 222.0
DTH2_k127_3946909_3 HIT domain K02503 - - 0.000000000000000000000000000000000000000000772 160.0
DTH2_k127_3946909_4 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000004554 67.0
DTH2_k127_3961781_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
DTH2_k127_3961781_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000009315 169.0
DTH2_k127_3961781_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000002343 148.0
DTH2_k127_3961781_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.00000000000000000000000000895 115.0
DTH2_k127_3983943_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 506.0
DTH2_k127_3983943_1 Cysteine desulfurase K04487 - 2.8.1.7 0.00000000007303 63.0
DTH2_k127_3998758_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003434 266.0
DTH2_k127_3998758_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000451 67.0
DTH2_k127_4000791_0 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
DTH2_k127_4000791_1 phosphoglycerate mutase activity K01834 GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000005474 227.0
DTH2_k127_4000791_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000004925 114.0
DTH2_k127_4000791_4 - - - - 0.0000000002302 63.0
DTH2_k127_4026602_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001194 256.0
DTH2_k127_4026602_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000001598 231.0
DTH2_k127_4026602_2 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000006293 147.0
DTH2_k127_4026602_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000004629 130.0
DTH2_k127_403620_0 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000005656 228.0
DTH2_k127_403620_1 PFAM PHP domain - - - 0.000000000000000000000003853 111.0
DTH2_k127_403620_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000009514 101.0
DTH2_k127_403620_3 - - - - 0.0000000000000008375 83.0
DTH2_k127_403620_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.0000000000002485 77.0
DTH2_k127_403620_5 Disintegrin and metalloproteinase domain-containing protein 9-like K08609,K08610,K08611,K08612,K08613,K16069 GO:0000003,GO:0001775,GO:0003674,GO:0003824,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0007276,GO:0007283,GO:0007338,GO:0007339,GO:0007343,GO:0008037,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009566,GO:0009897,GO:0009986,GO:0009987,GO:0009988,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0019953,GO:0022414,GO:0030424,GO:0031224,GO:0031226,GO:0032501,GO:0032504,GO:0035036,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043170,GO:0043900,GO:0043901,GO:0044238,GO:0044297,GO:0044425,GO:0044459,GO:0044464,GO:0044703,GO:0044877,GO:0048232,GO:0048519,GO:0048609,GO:0050789,GO:0050839,GO:0051704,GO:0060467,GO:0060468,GO:0061827,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080154,GO:0097223,GO:0097458,GO:0097524,GO:0098552,GO:0098590,GO:0120025,GO:0140096,GO:1901564,GO:1990913,GO:2000241,GO:2000242 - 0.00003052 56.0
DTH2_k127_4042320_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 337.0
DTH2_k127_4042320_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000008656 202.0
DTH2_k127_4042320_2 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000004709 187.0
DTH2_k127_4043146_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 393.0
DTH2_k127_4043146_1 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 377.0
DTH2_k127_4043146_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008654 272.0
DTH2_k127_4043146_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
DTH2_k127_4043146_4 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K00595 - 2.1.1.132 0.0000000000000007404 82.0
DTH2_k127_4043146_5 small metal-binding protein - - - 0.00005104 51.0
DTH2_k127_4043146_6 - - - - 0.000293 51.0
DTH2_k127_4055365_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 449.0
DTH2_k127_4055365_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000002728 228.0
DTH2_k127_4055365_2 PFAM thioesterase superfamily K01073 - 3.1.2.20 0.000000000000000000000000000001695 127.0
DTH2_k127_4055365_3 SMART Cold shock protein K03704 - - 0.0000000000000000000008089 96.0
DTH2_k127_4055365_4 Rhodanese Homology Domain - - - 0.000000000000000000005314 100.0
DTH2_k127_4055365_5 - - - - 0.00000000000000000002402 97.0
DTH2_k127_4055365_6 deoxyhypusine monooxygenase activity - - - 0.000000000000000004255 90.0
DTH2_k127_4055365_7 - - - - 0.0001035 53.0
DTH2_k127_4061628_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 347.0
DTH2_k127_4061628_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000001531 224.0
DTH2_k127_4061628_2 PIN domain - - - 0.0000000000000000000000000000005019 126.0
DTH2_k127_4061628_3 SpoVT / AbrB like domain - - - 0.000000000000000001631 87.0
DTH2_k127_4061628_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00005899 51.0
DTH2_k127_40617_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001748 286.0
DTH2_k127_40617_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000008648 120.0
DTH2_k127_40617_2 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000001101 87.0
DTH2_k127_40617_3 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000006014 66.0
DTH2_k127_40617_4 cheY-homologous receiver domain - - - 0.0000000113 59.0
DTH2_k127_40617_5 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.000006375 54.0
DTH2_k127_4083947_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 312.0
DTH2_k127_4083947_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
DTH2_k127_4083947_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000002035 174.0
DTH2_k127_4083947_3 PAC sensor-containing diguanylate cyclase - - - 0.000000000000000000000000000000000001367 156.0
DTH2_k127_4083947_4 HNH nucleases - - - 0.00000000000000000000000000000000002062 138.0
DTH2_k127_4083947_5 class II (D K and N) K04568 - - 0.000000000000000000000000000175 125.0
DTH2_k127_4083947_6 His Kinase A (phosphoacceptor) domain - - - 0.000001555 61.0
DTH2_k127_4111252_0 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 565.0
DTH2_k127_4111252_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 395.0
DTH2_k127_4142421_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 329.0
DTH2_k127_4142421_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 318.0
DTH2_k127_4142421_2 HIT domain - - - 0.000000000000000000000009254 103.0
DTH2_k127_4142421_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000003625 96.0
DTH2_k127_4142421_4 Yqey-like protein K09117 - - 0.00000000000000000003926 100.0
DTH2_k127_4145730_0 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000001215 181.0
DTH2_k127_4145730_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000004952 170.0
DTH2_k127_4145730_2 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000001303 104.0
DTH2_k127_4171553_0 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 433.0
DTH2_k127_4171553_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 379.0
DTH2_k127_4171553_2 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 347.0
DTH2_k127_4171553_3 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000258 208.0
DTH2_k127_4171553_4 tRNA processing - - - 0.00000000000000000000161 107.0
DTH2_k127_4177036_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 301.0
DTH2_k127_4177036_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000005432 179.0
DTH2_k127_4177036_2 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000001294 179.0
DTH2_k127_4177036_3 YGGT family K02221 - - 0.00000000000000000000000000002927 119.0
DTH2_k127_418720_0 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000000000001833 199.0
DTH2_k127_418720_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000000000000000000004061 149.0
DTH2_k127_418720_2 lyase activity - - - 0.0000000000000000000000002132 112.0
DTH2_k127_418720_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000006095 102.0
DTH2_k127_418720_4 Ribbon-helix-helix protein, copG family - - - 0.000000000000000005493 87.0
DTH2_k127_418720_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000001223 80.0
DTH2_k127_418720_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0002967 48.0
DTH2_k127_4188027_0 GAF domain - - - 2.551e-196 664.0
DTH2_k127_4188027_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 433.0
DTH2_k127_4188027_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 311.0
DTH2_k127_4188027_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000005169 166.0
DTH2_k127_4188027_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000002339 120.0
DTH2_k127_4188027_5 Belongs to the PEP-utilizing enzyme family K08484 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 0.000000000000000001107 103.0
DTH2_k127_4190219_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1478.0
DTH2_k127_4190219_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000009226 157.0
DTH2_k127_4196729_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 445.0
DTH2_k127_4196729_1 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000001483 196.0
DTH2_k127_4196729_2 - - - - 0.0000000000000000000000000000000000007283 143.0
DTH2_k127_4196729_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000001617 127.0
DTH2_k127_4200267_0 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000001552 173.0
DTH2_k127_4200267_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000006435 106.0
DTH2_k127_4200267_2 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.00007672 54.0
DTH2_k127_4203615_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 3.058e-281 888.0
DTH2_k127_4203615_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 593.0
DTH2_k127_4203615_2 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 322.0
DTH2_k127_4222780_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 415.0
DTH2_k127_4222780_1 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000012 150.0
DTH2_k127_4222780_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000006995 107.0
DTH2_k127_4261450_0 Lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 286.0
DTH2_k127_4261450_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000389 57.0
DTH2_k127_4287221_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000884 223.0
DTH2_k127_4287221_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000227 85.0
DTH2_k127_4287221_2 Bacterial SH3 domain homologues K07184 - - 0.00000000000008161 78.0
DTH2_k127_4464829_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 477.0
DTH2_k127_4464829_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 376.0
DTH2_k127_4464829_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000014 179.0
DTH2_k127_4464829_3 Cytochrome c K02305 - - 0.00000000005157 68.0
DTH2_k127_4464829_4 Belongs to the glycosyl hydrolase 3 family K01207,K05349 - 3.2.1.21,3.2.1.52 0.00008729 50.0
DTH2_k127_448752_0 Histidine kinase - - - 3.807e-226 735.0
DTH2_k127_448752_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 349.0
DTH2_k127_448752_2 Histidine kinase - - - 0.000000001536 70.0
DTH2_k127_4499506_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002995 260.0
DTH2_k127_4499506_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K02491,K13533 - 2.7.13.3 0.00000000000000000000000000234 128.0
DTH2_k127_4499506_2 Copper chaperone K07213 - - 0.000000000002353 69.0
DTH2_k127_4499506_3 GGDEF domain containing protein - - - 0.00001095 58.0
DTH2_k127_4561741_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.237e-200 630.0
DTH2_k127_4561741_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 479.0
DTH2_k127_4561741_10 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002607 211.0
DTH2_k127_4561741_11 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000001779 202.0
DTH2_k127_4561741_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000009405 197.0
DTH2_k127_4561741_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000002433 187.0
DTH2_k127_4561741_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000006769 183.0
DTH2_k127_4561741_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002473 182.0
DTH2_k127_4561741_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000002592 172.0
DTH2_k127_4561741_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000001466 171.0
DTH2_k127_4561741_18 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000002613 168.0
DTH2_k127_4561741_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000004859 154.0
DTH2_k127_4561741_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 359.0
DTH2_k127_4561741_20 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.00000000000000000000000000000000000002303 143.0
DTH2_k127_4561741_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000341 144.0
DTH2_k127_4561741_22 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000029 138.0
DTH2_k127_4561741_23 Ribosomal protein L22p/L17e K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000637 124.0
DTH2_k127_4561741_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000007876 122.0
DTH2_k127_4561741_25 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000506 128.0
DTH2_k127_4561741_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001689 113.0
DTH2_k127_4561741_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000006812 107.0
DTH2_k127_4561741_28 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000007862 112.0
DTH2_k127_4561741_29 Smr domain - - - 0.000000000000000000001827 96.0
DTH2_k127_4561741_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 352.0
DTH2_k127_4561741_30 Ribosomal protein L36 K02919 - - 0.0000000000000982 72.0
DTH2_k127_4561741_31 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000006779 67.0
DTH2_k127_4561741_32 - - - - 0.000000002526 68.0
DTH2_k127_4561741_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 317.0
DTH2_k127_4561741_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 313.0
DTH2_k127_4561741_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
DTH2_k127_4561741_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003451 257.0
DTH2_k127_4561741_8 rRNA binding K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
DTH2_k127_4561741_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001368 218.0
DTH2_k127_4572220_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 538.0
DTH2_k127_4572220_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 289.0
DTH2_k127_4572220_2 YbbR-like protein - - - 0.00000000000000000000000000000000001866 143.0
DTH2_k127_4572220_3 Pterin binding enzyme K00796 - 2.5.1.15 0.000003583 49.0
DTH2_k127_4577481_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 312.0
DTH2_k127_4577481_1 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
DTH2_k127_4577481_2 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000001005 173.0
DTH2_k127_4586972_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000158 269.0
DTH2_k127_4586972_1 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000184 252.0
DTH2_k127_4620653_0 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000002389 214.0
DTH2_k127_4620653_1 FecR protein - - - 0.00000000000000000000000000000000000000000008689 164.0
DTH2_k127_4620653_2 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K01768,K07814 - 4.6.1.1 0.000000000000000000000000000000000002828 141.0
DTH2_k127_4620653_3 Peptidase family M9 N-terminal - - - 0.000001004 61.0
DTH2_k127_4620653_4 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000003057 60.0
DTH2_k127_4624750_0 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 352.0
DTH2_k127_4624750_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000162 81.0
DTH2_k127_4655583_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 361.0
DTH2_k127_4655583_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 336.0
DTH2_k127_4655583_2 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000004992 179.0
DTH2_k127_4655583_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000001527 117.0
DTH2_k127_4655583_4 PFAM VacJ family lipoprotein K04754 - - 0.00000006864 53.0
DTH2_k127_4676163_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 460.0
DTH2_k127_4676163_1 YacP-like NYN domain K06962 - - 0.00000000000001112 80.0
DTH2_k127_4676163_2 Membrane - - - 0.00000000003915 67.0
DTH2_k127_4686041_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000002241 200.0
DTH2_k127_4686041_1 MGS-like domain - - - 0.00000000000000000000000000000000000000000000000000008375 194.0
DTH2_k127_4686041_2 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000001421 185.0
DTH2_k127_4686041_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001986 83.0
DTH2_k127_4686041_4 Protein of unknown function (DUF448) K07742 - - 0.0000000000000002661 83.0
DTH2_k127_4686041_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000001176 56.0
DTH2_k127_4692666_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 415.0
DTH2_k127_4692666_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 402.0
DTH2_k127_4692666_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002667 256.0
DTH2_k127_4743408_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 4.135e-201 640.0
DTH2_k127_4743408_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 428.0
DTH2_k127_4743408_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 384.0
DTH2_k127_4760023_0 Belongs to the CarB family K01955 - 6.3.5.5 4.365e-242 758.0
DTH2_k127_4760023_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002583 274.0
DTH2_k127_4820634_0 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000000000351 228.0
DTH2_k127_4820634_1 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000001951 185.0
DTH2_k127_4820634_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000003581 134.0
DTH2_k127_4820634_4 Plasmid stabilization system - - - 0.000000000008711 66.0
DTH2_k127_4824363_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 346.0
DTH2_k127_4824363_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000001262 135.0
DTH2_k127_4824363_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000004853 98.0
DTH2_k127_4886448_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 390.0
DTH2_k127_4886448_1 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000001133 115.0
DTH2_k127_49711_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 386.0
DTH2_k127_49711_1 Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 376.0
DTH2_k127_49711_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 317.0
DTH2_k127_49711_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000361 141.0
DTH2_k127_49711_4 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000005918 123.0
DTH2_k127_49711_5 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000005531 112.0
DTH2_k127_4972520_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 312.0
DTH2_k127_499112_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 313.0
DTH2_k127_499112_1 EamA-like transporter family K15269 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000003224 140.0
DTH2_k127_502324_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.625e-194 629.0
DTH2_k127_502324_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 364.0
DTH2_k127_502324_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 354.0
DTH2_k127_5055499_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000003296 203.0
DTH2_k127_5055499_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000001971 82.0
DTH2_k127_5055499_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000002674 60.0
DTH2_k127_5061437_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 340.0
DTH2_k127_5061437_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 304.0
DTH2_k127_5061437_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000002809 246.0
DTH2_k127_5061437_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000002595 143.0
DTH2_k127_5061437_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000174 127.0
DTH2_k127_5061437_5 negative regulation of ribosome biogenesis K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.0000000000000000000000002732 113.0
DTH2_k127_5077228_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1130.0
DTH2_k127_5077228_1 diguanylate cyclase - - - 0.000000000000000000000000000000002634 142.0
DTH2_k127_5081000_0 Histidine kinase - - - 0.000000000000000000000000000000000000002632 166.0
DTH2_k127_5081000_1 Histidine kinase - - - 0.0000000000008066 81.0
DTH2_k127_5083740_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 529.0
DTH2_k127_5083740_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 476.0
DTH2_k127_5083740_10 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000005673 116.0
DTH2_k127_5083740_11 Cell division protein FtsQ K03589 - - 0.00000000000001788 83.0
DTH2_k127_5083740_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 414.0
DTH2_k127_5083740_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 386.0
DTH2_k127_5083740_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 340.0
DTH2_k127_5083740_5 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 327.0
DTH2_k127_5083740_6 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 323.0
DTH2_k127_5083740_7 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000005844 228.0
DTH2_k127_5083740_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000002159 198.0
DTH2_k127_5083740_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001718 154.0
DTH2_k127_509361_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 525.0
DTH2_k127_5096295_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 391.0
DTH2_k127_5096295_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 301.0
DTH2_k127_5096295_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008307 259.0
DTH2_k127_5096295_3 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000003599 89.0
DTH2_k127_5099696_0 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 541.0
DTH2_k127_5099696_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 456.0
DTH2_k127_5099696_2 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002292 270.0
DTH2_k127_5105262_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1010.0
DTH2_k127_5105262_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 377.0
DTH2_k127_5105262_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 375.0
DTH2_k127_5110334_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 389.0
DTH2_k127_5110334_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000001646 194.0
DTH2_k127_5110334_2 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000007755 168.0
DTH2_k127_5110334_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000004022 68.0
DTH2_k127_5134159_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 9.616e-230 721.0
DTH2_k127_5134159_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 1.904e-199 635.0
DTH2_k127_5134159_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 510.0
DTH2_k127_5134159_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003146 289.0
DTH2_k127_5134159_4 S4 RNA-binding domain K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000001271 247.0
DTH2_k127_5134159_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000001688 157.0
DTH2_k127_5134159_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000000009234 140.0
DTH2_k127_5134159_7 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000006755 121.0
DTH2_k127_5134159_8 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000001779 98.0
DTH2_k127_5139184_0 PFAM methyl-viologen-reducing hydrogenase delta subunit K16886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 356.0
DTH2_k127_5139184_1 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 357.0
DTH2_k127_5139184_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000002267 96.0
DTH2_k127_5158605_0 ATPase BadF BadG BcrA BcrD type - - - 8.136e-217 688.0
DTH2_k127_5168728_0 GTP-binding GTPase Middle Region K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 552.0
DTH2_k127_5168728_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000294 56.0
DTH2_k127_5172135_0 Lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 430.0
DTH2_k127_5172135_1 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 321.0
DTH2_k127_5172135_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000004422 194.0
DTH2_k127_5173487_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 540.0
DTH2_k127_5175622_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 362.0
DTH2_k127_5175622_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 346.0
DTH2_k127_5175622_2 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 336.0
DTH2_k127_5175622_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000001657 161.0
DTH2_k127_5186641_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 4.897e-200 632.0
DTH2_k127_5186641_1 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000004115 170.0
DTH2_k127_5194789_0 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 599.0
DTH2_k127_5194789_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000003898 192.0
DTH2_k127_5202485_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000005709 190.0
DTH2_k127_5202485_1 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000003075 202.0
DTH2_k127_5202485_3 - - - - 0.0000000000000000000009614 98.0
DTH2_k127_5202485_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000005677 65.0
DTH2_k127_5204023_0 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000001417 174.0
DTH2_k127_520775_0 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 3.106e-219 704.0
DTH2_k127_520775_1 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000001764 210.0
DTH2_k127_520775_2 peptidase M42 family protein - - - 0.0000000000000000000000000000000003502 133.0
DTH2_k127_5209081_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 501.0
DTH2_k127_5209081_1 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 355.0
DTH2_k127_5209081_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 357.0
DTH2_k127_5209081_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002391 269.0
DTH2_k127_5209081_4 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000001646 126.0
DTH2_k127_5209081_5 OstA-like protein K09774 - - 0.00000000000000000000000008691 114.0
DTH2_k127_5209081_6 Participates in both transcription termination and antitermination K02600 - - 0.000000001617 61.0
DTH2_k127_5217827_0 PFAM Carbamoyltransferase K00612 - - 7.012e-286 885.0
DTH2_k127_5217827_1 Catalyzes the addition of the first glucose residue to the LPS core K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 436.0
DTH2_k127_5231288_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 588.0
DTH2_k127_5231288_1 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 309.0
DTH2_k127_5231288_2 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 314.0
DTH2_k127_5231288_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000003708 96.0
DTH2_k127_5231288_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.0000000000000000000293 102.0
DTH2_k127_5231533_0 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004683 280.0
DTH2_k127_5231533_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
DTH2_k127_5234311_0 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 297.0
DTH2_k127_5234311_1 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 294.0
DTH2_k127_5234311_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 297.0
DTH2_k127_5234311_3 Thioredoxin K03672 - 1.8.1.8 0.0008767 48.0
DTH2_k127_5237316_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 389.0
DTH2_k127_5237316_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000003237 82.0
DTH2_k127_5255229_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 536.0
DTH2_k127_5255229_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000008636 152.0
DTH2_k127_5255229_2 transmembrane signaling receptor activity K00575,K03406,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000003201 136.0
DTH2_k127_5255229_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0001124 46.0
DTH2_k127_5258951_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 546.0
DTH2_k127_5264303_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
DTH2_k127_5264303_1 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000273 181.0
DTH2_k127_5264747_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000003058 212.0
DTH2_k127_5264747_1 - - - - 0.00000000000000000000000004839 113.0
DTH2_k127_5264892_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.906e-272 850.0
DTH2_k127_5264892_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 541.0
DTH2_k127_5264892_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 352.0
DTH2_k127_5264892_3 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000001389 242.0
DTH2_k127_5264892_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000005143 209.0
DTH2_k127_5264892_5 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000004043 166.0
DTH2_k127_5264892_6 - - - - 0.0000000000000000000000000000000425 133.0
DTH2_k127_5264892_7 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000002832 89.0
DTH2_k127_5264892_8 Rubrerythrin - - - 0.00000000000000008441 89.0
DTH2_k127_5265194_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 409.0
DTH2_k127_5265194_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000001084 79.0
DTH2_k127_5267997_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 589.0
DTH2_k127_5267997_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 394.0
DTH2_k127_5267997_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 358.0
DTH2_k127_5267997_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000004474 128.0
DTH2_k127_5267997_4 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000007851 95.0
DTH2_k127_5275341_0 protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000000006146 185.0
DTH2_k127_5275341_1 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000001193 134.0
DTH2_k127_5275341_2 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000004806 126.0
DTH2_k127_5275341_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000001331 107.0
DTH2_k127_5275341_4 - - - - 0.000000000000000000000141 102.0
DTH2_k127_5275341_5 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000006034 100.0
DTH2_k127_5275341_6 YqjK-like protein - - - 0.0000000000007272 77.0
DTH2_k127_5275341_7 response regulator, receiver - - - 0.00001253 56.0
DTH2_k127_5299204_0 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 329.0
DTH2_k127_5299204_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 317.0
DTH2_k127_5299204_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000762 240.0
DTH2_k127_5328026_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 5.18e-308 957.0
DTH2_k127_5328026_1 PFAM Acetyl-CoA hydrolase transferase - - - 2.642e-269 849.0
DTH2_k127_5328026_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 602.0
DTH2_k127_5330099_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1125.0
DTH2_k127_5330099_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000003906 136.0
DTH2_k127_5330099_2 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000003056 119.0
DTH2_k127_5330099_3 GTP-binding GTPase Middle Region K03665 - - 0.00000000000000000005389 94.0
DTH2_k127_5330099_4 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000000000000008479 100.0
DTH2_k127_5346792_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 401.0
DTH2_k127_5346792_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000001591 235.0
DTH2_k127_5346792_2 Domain of unknown function DUF302 - - - 0.00000000005041 63.0
DTH2_k127_538014_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 304.0
DTH2_k127_538014_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005848 260.0
DTH2_k127_538014_2 DNA-binding protein VF530 - - - 0.000000000000000000000000002836 112.0
DTH2_k127_538014_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000003145 91.0
DTH2_k127_538014_4 YwiC-like protein - - - 0.00000000005796 72.0
DTH2_k127_538014_5 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000008682 53.0
DTH2_k127_5397669_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
DTH2_k127_5397669_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 413.0
DTH2_k127_5397669_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000001054 154.0
DTH2_k127_5397669_3 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001509 80.0
DTH2_k127_5398889_0 formate C-acetyltransferase glycine radical - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 630.0
DTH2_k127_5398889_1 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 289.0
DTH2_k127_5398889_2 - - - - 0.00000000000000000000000000000000000000000000000000000000001924 209.0
DTH2_k127_5417148_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 1.438e-235 743.0
DTH2_k127_5417148_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 442.0
DTH2_k127_5417148_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001533 173.0
DTH2_k127_5417148_3 response regulator - - - 0.0000000000000000000000000000000007559 134.0
DTH2_k127_5417148_4 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000006039 125.0
DTH2_k127_5417148_5 Bacterial regulatory protein, Fis family K10126,K17061 - - 0.0000000000000000000001145 109.0
DTH2_k127_5417148_6 Belongs to the HesB IscA family - - - 0.00000000000001382 75.0
DTH2_k127_5421552_0 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000883 285.0
DTH2_k127_5421552_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000001614 127.0
DTH2_k127_5421552_2 flagellar protein FliS K02422 - - 0.000000000000000000001435 100.0
DTH2_k127_5421552_3 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.0000000000002637 77.0
DTH2_k127_5426417_0 Thioredoxin reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000001327 207.0
DTH2_k127_5426417_1 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000003179 192.0
DTH2_k127_5432721_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0 1319.0
DTH2_k127_5432721_1 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 1.978e-265 827.0
DTH2_k127_5432721_2 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 342.0
DTH2_k127_5432721_3 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 319.0
DTH2_k127_5432721_4 radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000002229 218.0
DTH2_k127_5432721_5 - - - - 0.00000000000000000000000000000001508 132.0
DTH2_k127_5432721_6 - - - - 0.000000000000000000003129 97.0
DTH2_k127_5432721_7 PFAM DAHP synthetase I K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000002413 72.0
DTH2_k127_5454476_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 587.0
DTH2_k127_5454476_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 509.0
DTH2_k127_5454476_2 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000003621 69.0
DTH2_k127_5508020_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 523.0
DTH2_k127_5508020_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000059 288.0
DTH2_k127_5508020_2 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009079 258.0
DTH2_k127_5521261_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1358.0
DTH2_k127_5521261_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000004925 234.0
DTH2_k127_5529873_0 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131 302.0
DTH2_k127_5529873_1 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.00000000000000000002712 92.0
DTH2_k127_5529873_2 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000007303 68.0
DTH2_k127_5548928_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 4.259e-251 792.0
DTH2_k127_5548928_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000001975 235.0
DTH2_k127_5548928_2 SRP54-type protein, GTPase domain K02404 - - 0.00000000000000001283 92.0
DTH2_k127_5550736_0 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000001272 175.0
DTH2_k127_5550736_1 Flagellar hook capping protein - N-terminal region K02389 - - 0.000000000000000000000000000000000004152 145.0
DTH2_k127_5550736_2 Flagellar hook-length control protein K02414 - - 0.0004208 52.0
DTH2_k127_5560815_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000003448 266.0
DTH2_k127_5560815_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000005537 171.0
DTH2_k127_5560815_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000004345 85.0
DTH2_k127_5567020_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K18138 - - 0.0 1615.0
DTH2_k127_5567020_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 589.0
DTH2_k127_5567020_2 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 418.0
DTH2_k127_5567020_3 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000000005122 201.0
DTH2_k127_5567020_4 - - - - 0.0000000000000000000000000000000001985 133.0
DTH2_k127_5567020_5 Catalyzes the synthesis of activated sulfate K00860,K00955,K00958 - 2.7.1.25,2.7.7.4 0.000000000000000000000000002156 111.0
DTH2_k127_5567020_6 PFAM Fe-S cluster domain protein - - - 0.0000000000000000000003354 97.0
DTH2_k127_5584605_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 447.0
DTH2_k127_5584605_1 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000000000000178 182.0
DTH2_k127_5584605_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000004338 173.0
DTH2_k127_5585338_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 475.0
DTH2_k127_5585338_1 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001408 276.0
DTH2_k127_5585338_2 Protein conserved in bacteria - - - 0.00006409 54.0
DTH2_k127_5592935_0 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 400.0
DTH2_k127_5592935_1 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000001988 216.0
DTH2_k127_5592935_2 Flagellar basal body rod protein - - - 0.000000000821 62.0
DTH2_k127_5597254_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 464.0
DTH2_k127_5597254_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 264.0
DTH2_k127_5597254_2 response regulator - - - 0.000000000000000000000000000000000000000000000001687 177.0
DTH2_k127_5597254_3 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000007699 106.0
DTH2_k127_5597254_4 phosphorelay signal transduction system K03413 - - 0.000003942 55.0
DTH2_k127_5602783_0 glycolate transport K14393 - - 4.368e-232 731.0
DTH2_k127_5605629_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.3e-278 871.0
DTH2_k127_5605629_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000001019 196.0
DTH2_k127_5605629_2 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000002346 147.0
DTH2_k127_5605629_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000005214 126.0
DTH2_k127_562817_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 446.0
DTH2_k127_562817_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 370.0
DTH2_k127_562817_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 320.0
DTH2_k127_562817_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 306.0
DTH2_k127_5631750_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.299e-201 638.0
DTH2_k127_5631750_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001082 264.0
DTH2_k127_563309_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 522.0
DTH2_k127_563309_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 458.0
DTH2_k127_563309_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 389.0
DTH2_k127_563309_3 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000002957 212.0
DTH2_k127_563309_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000002862 128.0
DTH2_k127_563309_5 ADP-ribosylglycohydrolase - - - 0.000000000000000000000006304 105.0
DTH2_k127_563309_6 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000001047 108.0
DTH2_k127_5645217_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 9.512e-243 756.0
DTH2_k127_5645217_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.512e-201 636.0
DTH2_k127_5645217_2 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000009125 185.0
DTH2_k127_5645217_3 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000001464 151.0
DTH2_k127_56659_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007406 284.0
DTH2_k127_56659_1 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000003359 241.0
DTH2_k127_56659_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000001283 166.0
DTH2_k127_56659_3 COG0457 FOG TPR repeat - - - 0.0008791 47.0
DTH2_k127_5669056_0 Highly conserved protein containing a thioredoxin domain K06888 - - 3.823e-214 680.0
DTH2_k127_5669056_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 342.0
DTH2_k127_5733892_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 3.425e-202 637.0
DTH2_k127_5733892_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000002047 248.0
DTH2_k127_5733892_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000005868 219.0
DTH2_k127_5733892_3 bile acid:sodium symporter activity K03453 - - 0.000000003279 61.0
DTH2_k127_5755215_0 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 391.0
DTH2_k127_5755215_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001838 278.0
DTH2_k127_5755215_2 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000001629 218.0
DTH2_k127_5755215_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000007517 181.0
DTH2_k127_5755215_4 Ion transport 2 domain protein - - - 0.0000000000000000000000000000000000005106 149.0
DTH2_k127_5757633_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002163 262.0
DTH2_k127_5757633_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000007953 235.0
DTH2_k127_5757633_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000002298 200.0
DTH2_k127_5757633_3 cytochrome complex assembly - - - 0.000000000000000000004608 98.0
DTH2_k127_577863_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000174 274.0
DTH2_k127_577863_1 PFAM Anti-sigma-28 factor FlgM K02398 - - 0.000004442 53.0
DTH2_k127_577863_2 Belongs to the bacterial flagellin family K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00002569 47.0
DTH2_k127_580390_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000389 249.0
DTH2_k127_580390_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000001313 136.0
DTH2_k127_580390_2 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000007761 65.0
DTH2_k127_580390_3 General secretion pathway protein K02459 - - 0.00007396 53.0
DTH2_k127_5820702_0 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 515.0
DTH2_k127_5820702_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 334.0
DTH2_k127_5820702_2 Psort location Cytoplasmic, score K00821 - 2.6.1.11,2.6.1.17 0.00000004085 55.0
DTH2_k127_5852471_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 539.0
DTH2_k127_5852471_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 406.0
DTH2_k127_5852471_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
DTH2_k127_5852471_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000002135 187.0
DTH2_k127_5852471_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000001436 167.0
DTH2_k127_5852471_5 SMART HNH nuclease K07451 - - 0.000000000000000000000000000000001046 132.0
DTH2_k127_5852471_6 DnaJ protein - - - 0.0000000008685 72.0
DTH2_k127_5852471_7 regulator, PATAN and FRGAF domain-containing - - - 0.0001766 54.0
DTH2_k127_5988451_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 341.0
DTH2_k127_5988451_1 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000008485 183.0
DTH2_k127_5988451_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000009275 52.0
DTH2_k127_6044678_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
DTH2_k127_6044678_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
DTH2_k127_6044678_2 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005693 261.0
DTH2_k127_6044678_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000003174 85.0
DTH2_k127_6180941_0 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000001797 237.0
DTH2_k127_6180941_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000003065 227.0
DTH2_k127_6244520_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1161.0
DTH2_k127_6244520_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 289.0
DTH2_k127_6244520_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000002015 91.0
DTH2_k127_6310781_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 506.0
DTH2_k127_6310781_1 WYL domain K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004394 279.0
DTH2_k127_6310781_2 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000001042 161.0
DTH2_k127_6310781_3 EXOIII K02342 - 2.7.7.7 0.0000000003068 64.0
DTH2_k127_6326440_0 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002206 282.0
DTH2_k127_6326440_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004285 272.0
DTH2_k127_6326440_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000001585 190.0
DTH2_k127_6326440_3 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000005596 153.0
DTH2_k127_6336709_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 377.0
DTH2_k127_6336709_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000085 207.0
DTH2_k127_6336709_2 synthase - - - 0.000000000000965 79.0
DTH2_k127_6336709_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000002832 65.0
DTH2_k127_6340221_0 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000104 137.0
DTH2_k127_6340221_1 Rhodanese Homology Domain - - - 0.000000000000000002875 86.0
DTH2_k127_6340221_2 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000002685 64.0
DTH2_k127_6340221_3 DsrE/DsrF-like family K07235 - - 0.000000002534 63.0
DTH2_k127_6340221_4 sulfur relay protein TusB DsrH K07237 - - 0.000002684 51.0
DTH2_k127_6343598_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 361.0
DTH2_k127_6343598_1 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007025 280.0
DTH2_k127_6343598_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000002609 262.0
DTH2_k127_6343598_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000001304 148.0
DTH2_k127_6351063_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 406.0
DTH2_k127_6351063_1 Thiamine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 320.0
DTH2_k127_6351063_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region K03407,K07678,K18143 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000003039 236.0
DTH2_k127_6351063_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
DTH2_k127_6351063_4 PFAM Rhodanese domain protein - - - 0.0000000000000000000000009659 119.0
DTH2_k127_6351063_5 Protein of unknown function (DUF541) - - - 0.0000000000000000000004817 104.0
DTH2_k127_6351063_6 electron transfer activity K05337 - - 0.000000000000005225 76.0
DTH2_k127_6351063_7 Flavin reductase like domain - - - 0.000001248 57.0
DTH2_k127_6352610_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
DTH2_k127_6352610_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 303.0
DTH2_k127_6352610_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000006205 148.0
DTH2_k127_6352610_3 - - - - 0.000000005918 61.0
DTH2_k127_6356462_0 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 545.0
DTH2_k127_6356462_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000003384 120.0
DTH2_k127_6356462_2 cAMP biosynthetic process - - - 0.00000000000004605 73.0
DTH2_k127_6364038_1 LysE type translocator - - - 0.0000000000000000000000000000000000000007582 158.0
DTH2_k127_6364038_2 Beta-lactamase superfamily domain - - - 0.00000000004302 63.0
DTH2_k127_6368865_0 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000937 183.0
DTH2_k127_6368865_1 peptidyl-tyrosine sulfation - - - 0.00000001639 62.0
DTH2_k127_6368865_2 STAS domain - - - 0.00001578 52.0
DTH2_k127_6403287_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 491.0
DTH2_k127_6403287_1 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.00000000000000000001698 91.0
DTH2_k127_6403287_2 PFAM HhH-GPD family protein K07457 - - 0.00000006238 55.0
DTH2_k127_6411986_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 357.0
DTH2_k127_6411986_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000003743 258.0
DTH2_k127_6411986_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000004548 169.0
DTH2_k127_6418312_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 415.0
DTH2_k127_6418312_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004171 272.0
DTH2_k127_6418312_2 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000002235 258.0
DTH2_k127_643182_0 PFAM Acetyl-CoA hydrolase transferase - - - 1.466e-202 648.0
DTH2_k127_643182_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 578.0
DTH2_k127_643182_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
DTH2_k127_643182_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001147 278.0
DTH2_k127_643182_5 Putative regulatory protein - - - 0.000000000000000000001777 98.0
DTH2_k127_643182_6 Major facilitator Superfamily - - - 0.00007327 51.0
DTH2_k127_6442476_0 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000002953 180.0
DTH2_k127_6442476_1 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000001541 177.0
DTH2_k127_6442476_2 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000001139 150.0
DTH2_k127_6442476_3 Tetratricopeptide repeat - - - 0.000000000000000000000001693 112.0
DTH2_k127_6442476_4 lyase activity - - - 0.00000000000000001573 90.0
DTH2_k127_6442476_5 lyase activity - - - 0.0001621 46.0
DTH2_k127_6450676_0 alpha amylase, catalytic region - - - 1.576e-253 790.0
DTH2_k127_6450676_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 477.0
DTH2_k127_6450676_2 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000011 203.0
DTH2_k127_6450676_3 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000000000000000000000005904 196.0
DTH2_k127_6450676_4 PFAM Mammalian cell entry related domain protein K06192 - - 0.00000000001001 66.0
DTH2_k127_6450676_5 Belongs to the ompA family K03286 - - 0.00001574 49.0
DTH2_k127_6485901_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003256 250.0
DTH2_k127_6491443_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 308.0
DTH2_k127_6491443_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007933 281.0
DTH2_k127_6491443_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000002273 161.0
DTH2_k127_6491443_3 HEAT repeats - - - 0.000000000000000000006493 106.0
DTH2_k127_6491486_0 CHASE4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 445.0
DTH2_k127_6491486_2 Two component signalling adaptor domain K03408 - - 0.000000000009057 67.0
DTH2_k127_6526713_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 252.0
DTH2_k127_6526713_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000007499 237.0
DTH2_k127_6526713_2 Histidine kinase K07642,K18143 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002969 238.0
DTH2_k127_6526713_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000002186 123.0
DTH2_k127_6526713_4 Belongs to the UPF0235 family K09131 - - 0.00000000000001546 79.0
DTH2_k127_6555089_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 515.0
DTH2_k127_6555089_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000007343 202.0
DTH2_k127_6555089_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000001699 112.0
DTH2_k127_6565527_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006432 278.0
DTH2_k127_6565527_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000007493 217.0
DTH2_k127_6565527_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002582 213.0
DTH2_k127_6565527_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000006398 182.0
DTH2_k127_6565527_4 impB/mucB/samB family K02346 - 2.7.7.7 0.0000000000000000000000000000000001804 138.0
DTH2_k127_6565527_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000004098 109.0
DTH2_k127_6565527_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000003123 88.0
DTH2_k127_6565527_7 Hexapeptide repeat of succinyl-transferase - - - 0.00001486 57.0
DTH2_k127_6566859_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 351.0
DTH2_k127_6566859_1 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 325.0
DTH2_k127_6566859_2 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001909 240.0
DTH2_k127_6566859_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000001948 222.0
DTH2_k127_6566859_4 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000008351 208.0
DTH2_k127_6566859_5 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000003597 177.0
DTH2_k127_6566859_6 TPM domain - - - 0.00000000000000000000000000000000000000036 157.0
DTH2_k127_6566859_7 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000004184 96.0
DTH2_k127_6571479_0 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000002626 142.0
DTH2_k127_6571479_1 PFAM FMN-binding domain - - - 0.000000000000000000000000000000000222 149.0
DTH2_k127_6605610_0 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000001373 148.0
DTH2_k127_6605610_1 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.000000000000000000000000000001188 126.0
DTH2_k127_6608339_0 translation release factor activity - - - 0.0000000000000000000000000007661 115.0
DTH2_k127_6608339_1 metal cluster binding K06940 - - 0.00000000000000001685 87.0
DTH2_k127_6622164_0 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000001143 177.0
DTH2_k127_6622164_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000001716 177.0
DTH2_k127_6622164_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000003656 139.0
DTH2_k127_6622164_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000324 94.0
DTH2_k127_6628681_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 330.0
DTH2_k127_6628681_1 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000601 203.0
DTH2_k127_6628681_2 - - - - 0.00000000000000000000000007822 117.0
DTH2_k127_6628681_3 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000003277 105.0
DTH2_k127_6628681_4 - - - - 0.0000000000000000004326 95.0
DTH2_k127_6640053_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 4.34e-315 973.0
DTH2_k127_6647954_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 374.0
DTH2_k127_6647954_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 314.0
DTH2_k127_6647954_2 Transglycosylase K08309 - - 0.00000000000000000000000000000000000000002854 163.0
DTH2_k127_6647954_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000265 93.0
DTH2_k127_6647954_4 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.0000344 48.0
DTH2_k127_6653342_0 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000000000000001219 140.0
DTH2_k127_6653342_1 - - - - 0.00000000000000000000000007091 116.0
DTH2_k127_6653342_2 antisigma factor binding K04749 - - 0.0000000000000000000001036 101.0
DTH2_k127_6653342_3 Rhodanese Homology Domain - - - 0.00000003262 63.0
DTH2_k127_6673026_0 UvrD/REP helicase N-terminal domain K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000008423 239.0
DTH2_k127_6691459_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 464.0
DTH2_k127_6691459_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 434.0
DTH2_k127_6691459_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 374.0
DTH2_k127_6691459_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000004651 217.0
DTH2_k127_6691459_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000007097 138.0
DTH2_k127_6721489_0 Chemotaxis phosphatase CheX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 307.0
DTH2_k127_6721489_1 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000148 199.0
DTH2_k127_6721489_2 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.0000000000000006805 82.0
DTH2_k127_6721489_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000001218 61.0
DTH2_k127_672339_0 Polyketide synthase dehydratase K13611,K15314 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004098 281.0
DTH2_k127_6753987_0 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 398.0
DTH2_k127_6753987_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 376.0
DTH2_k127_6778122_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 391.0
DTH2_k127_6778122_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000004622 208.0
DTH2_k127_6796315_0 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 402.0
DTH2_k127_6796315_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 389.0
DTH2_k127_6796315_2 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000009285 220.0
DTH2_k127_6846247_0 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 452.0
DTH2_k127_685213_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 595.0
DTH2_k127_685213_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 312.0
DTH2_k127_685213_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.000000000000000000000000000000000000000000000000000000000000000936 224.0
DTH2_k127_685213_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000002128 173.0
DTH2_k127_685213_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000005255 89.0
DTH2_k127_685213_5 HEAT-like repeat - - - 0.00000000401 62.0
DTH2_k127_6856844_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 546.0
DTH2_k127_6856844_1 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 353.0
DTH2_k127_6856844_2 PFAM Type IV pilus assembly PilZ - - - 0.000000000000000007083 88.0
DTH2_k127_6856844_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000006032 80.0
DTH2_k127_6856844_4 Polysaccharide biosynthesis/export protein K01991 - - 0.000000146 55.0
DTH2_k127_6870863_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 442.0
DTH2_k127_6870863_1 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000006222 192.0
DTH2_k127_6870863_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000002471 123.0
DTH2_k127_6898565_0 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 413.0
DTH2_k127_6898565_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000002176 222.0
DTH2_k127_6921655_0 PFAM CHASE2 domain - - - 1.289e-217 690.0
DTH2_k127_6921655_1 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000004167 195.0
DTH2_k127_6921655_2 ATP synthase gamma subunit K02115 - - 0.000000000000000000000000000000000000000000002873 173.0
DTH2_k127_693557_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 405.0
DTH2_k127_693557_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 341.0
DTH2_k127_6940748_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 380.0
DTH2_k127_6940748_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003973 248.0
DTH2_k127_6984011_0 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
DTH2_k127_6984011_1 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000202 213.0
DTH2_k127_6984011_2 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000006158 160.0
DTH2_k127_6984011_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000008422 154.0
DTH2_k127_6984011_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000001067 130.0
DTH2_k127_6984011_5 Protein of unknown function (DUF3592) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0001112 51.0
DTH2_k127_6986880_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.194e-209 698.0
DTH2_k127_6986880_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006731 248.0
DTH2_k127_6986880_2 His Kinase A (phospho-acceptor) domain K02485,K02488,K11443 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000001517 247.0
DTH2_k127_6986880_3 - - - - 0.000000000505 61.0
DTH2_k127_7021606_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 593.0
DTH2_k127_7096778_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 305.0
DTH2_k127_7096778_1 carboxylesterase involved in biosynthesis of pimeloyl-CoA carboxylesterase K02170 K02170 - 3.1.1.85 0.0000000000000000001811 97.0
DTH2_k127_7096778_2 trans-aconitate 2-methyltransferase activity K00563,K00598,K01935,K02169,K14251,K15256,K16868,K19104 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016740,GO:0016741,GO:0030798,GO:0031347,GO:0031348,GO:0032259,GO:0035821,GO:0040007,GO:0043207,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.1.1.144,2.1.1.187,2.1.1.197,2.1.1.265,2.5.1.38,6.3.3.3 0.0000000000000001445 87.0
DTH2_k127_7106009_0 Multicopper oxidase K22348 - 1.16.3.3 3.454e-282 869.0
DTH2_k127_7106009_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 503.0
DTH2_k127_7106009_10 cheY-homologous receiver domain - - - 0.000000001629 67.0
DTH2_k127_7106009_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
DTH2_k127_7106009_3 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 309.0
DTH2_k127_7106009_4 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 293.0
DTH2_k127_7106009_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
DTH2_k127_7106009_6 PFAM Blue (type 1) copper domain - - - 0.00000000000000000000000000000000000000000000000000000005092 200.0
DTH2_k127_7106009_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000005407 190.0
DTH2_k127_7106009_8 Copper binding periplasmic protein CusF - - - 0.0000000000000000000000007207 108.0
DTH2_k127_7106009_9 Histidine kinase K02660,K11525 - - 0.00000000000000000000001502 102.0
DTH2_k127_7106893_0 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 408.0
DTH2_k127_7106893_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000001871 128.0
DTH2_k127_7106893_2 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000007291 82.0
DTH2_k127_7107866_0 protein histidine kinase activity - - - 0.00000000000000000000000008161 120.0
DTH2_k127_7107866_1 Copper chaperone PCu(A)C K09796 - - 0.00000000214 66.0
DTH2_k127_7114059_0 Acyl-protein synthetase, LuxE - - - 1.326e-221 691.0
DTH2_k127_7114059_1 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000003428 242.0
DTH2_k127_7114059_2 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000002534 139.0
DTH2_k127_7131570_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.624e-196 624.0
DTH2_k127_7131570_1 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000007553 247.0
DTH2_k127_7131570_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000001936 110.0
DTH2_k127_7183783_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000002637 209.0
DTH2_k127_7183783_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000006011 199.0
DTH2_k127_7183783_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000006594 118.0
DTH2_k127_7183783_3 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.0006407 49.0
DTH2_k127_7187604_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000004145 219.0
DTH2_k127_7187604_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.00000000000000000000000000000000000000000000000000000000634 212.0
DTH2_k127_7195162_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 531.0
DTH2_k127_7195162_1 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000156 193.0
DTH2_k127_7195162_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000009833 127.0
DTH2_k127_7195162_3 General secretion pathway protein K02461 - - 0.0000002298 63.0
DTH2_k127_7195162_4 Type II secretion system (T2SS), protein M subtype b - - - 0.0001834 50.0
DTH2_k127_7327232_0 Polysaccharide biosynthesis protein K17716 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 522.0
DTH2_k127_7327232_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 408.0
DTH2_k127_7357056_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 607.0
DTH2_k127_7357056_1 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 392.0
DTH2_k127_7357056_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001593 190.0
DTH2_k127_7357056_3 crp fnr family K01420 - - 0.000000000000000000000000000000000000000000000001247 181.0
DTH2_k127_7357056_4 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000007723 176.0
DTH2_k127_7357056_5 Protein of unknown function (DUF2892) - - - 0.00000000000000000000002394 105.0
DTH2_k127_7378631_0 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 478.0
DTH2_k127_7378631_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000885 181.0
DTH2_k127_7378631_2 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000001203 129.0
DTH2_k127_7395176_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 332.0
DTH2_k127_7395176_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000001949 93.0
DTH2_k127_7395176_2 YtkA-like - - - 0.000000003202 60.0
DTH2_k127_74274_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000003471 189.0
DTH2_k127_74274_1 N2,N2-dimethylguanosine tRNA methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000001812 146.0
DTH2_k127_74274_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000007961 134.0
DTH2_k127_74274_3 - - - - 0.0000001914 53.0
DTH2_k127_74274_4 Shikimate quinate 5-dehydrogenase - - - 0.0002429 45.0
DTH2_k127_7435720_0 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000000000000000000712 198.0
DTH2_k127_7436110_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 583.0
DTH2_k127_7436110_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 319.0
DTH2_k127_7436110_2 Domain of unknown function (DUF4105) - - - 0.0000000000000003546 79.0
DTH2_k127_7436110_3 Flagellar Motor Protein K02557 - - 0.00004046 47.0
DTH2_k127_7543612_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 494.0
DTH2_k127_7543612_1 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 344.0
DTH2_k127_7543612_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 315.0
DTH2_k127_7543612_3 PFAM Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.00000000000000000000005294 108.0
DTH2_k127_755803_0 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 445.0
DTH2_k127_755803_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 419.0
DTH2_k127_755803_2 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003775 274.0
DTH2_k127_755803_3 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000267 121.0
DTH2_k127_7630092_0 PFAM multicopper oxidase type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 624.0
DTH2_k127_7630092_1 PFAM Response regulator receiver domain K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 521.0
DTH2_k127_7630092_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005891 283.0
DTH2_k127_7630092_3 - - - - 0.0000000000000000000000000000000001085 135.0
DTH2_k127_7630092_4 Response regulator receiver domain K03413 - - 0.00000005773 61.0
DTH2_k127_7634359_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 515.0
DTH2_k127_7634359_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000001045 128.0
DTH2_k127_7634359_2 shape-determining protein MreD K03571 - - 0.000009926 53.0
DTH2_k127_7639692_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 302.0
DTH2_k127_7639692_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002993 264.0
DTH2_k127_7639692_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006448 267.0
DTH2_k127_7639692_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000001335 214.0
DTH2_k127_7639692_4 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000001013 175.0
DTH2_k127_7639692_5 carbon dioxide binding K04653 - - 0.00000000000000000001123 94.0
DTH2_k127_7639692_6 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.00000000000000000008156 98.0
DTH2_k127_7639692_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000005194 60.0
DTH2_k127_7642300_0 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 296.0
DTH2_k127_7642300_1 pfam abc-3 K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003952 269.0
DTH2_k127_7642300_2 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
DTH2_k127_7642300_3 Belongs to the Fur family K09823 - - 0.000000000000000000000000000000000000000000000001204 179.0
DTH2_k127_7642300_4 Protein of unknown function (DUF1847) - - - 0.000000000000000006561 85.0
DTH2_k127_7659341_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.145e-251 784.0
DTH2_k127_7659341_1 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000001093 244.0
DTH2_k127_7659341_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000008619 164.0
DTH2_k127_7668877_0 PFAM LOR SDH bifunctional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005168 246.0
DTH2_k127_7668877_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - 0.0000000000000000000000000000000000000000000000002288 195.0
DTH2_k127_7668877_2 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000009725 180.0
DTH2_k127_7684195_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 358.0
DTH2_k127_7684195_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000006006 226.0
DTH2_k127_7701636_0 type IV pilus assembly PilZ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 580.0
DTH2_k127_7701636_1 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 443.0
DTH2_k127_7712264_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 365.0
DTH2_k127_7712264_1 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 306.0
DTH2_k127_7712264_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000006947 131.0
DTH2_k127_7712264_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000007625 113.0
DTH2_k127_7712264_5 Alternative locus ID K00748 - 2.4.1.182 0.00000234 50.0
DTH2_k127_7712264_6 - - - - 0.0002294 44.0
DTH2_k127_7714989_0 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 593.0
DTH2_k127_7715778_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 574.0
DTH2_k127_7715778_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000423 263.0
DTH2_k127_7715778_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000005661 257.0
DTH2_k127_7715778_3 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000004493 171.0
DTH2_k127_7715778_4 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000004886 161.0
DTH2_k127_7715778_5 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.00000000000000000000000000000000001041 145.0
DTH2_k127_7720213_0 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 410.0
DTH2_k127_7720213_1 PFAM amino acid-binding ACT domain protein K03567 - - 0.000000000000000000000000000000000000000000000000000000004149 204.0
DTH2_k127_7720213_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.00000000000000000000000000000000000001313 157.0
DTH2_k127_7720213_3 PFAM 4Fe-4S ferredoxin - - - 0.00001569 47.0
DTH2_k127_7720471_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 512.0
DTH2_k127_7720471_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000269 261.0
DTH2_k127_7720471_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000002826 157.0
DTH2_k127_7720471_3 COG0058 Glucan phosphorylase - - - 0.0000002637 54.0
DTH2_k127_7720471_4 - - - - 0.0002964 44.0
DTH2_k127_7723488_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000239 219.0
DTH2_k127_7723488_1 Belongs to the MraZ family K03925 - - 0.0000000000000000000000003741 108.0
DTH2_k127_7738116_0 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 484.0
DTH2_k127_7738116_1 COG0526, thiol-disulfide isomerase and thioredoxins K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000009308 246.0
DTH2_k127_7738116_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000001337 149.0
DTH2_k127_7738116_3 RDD family - - - 0.0000000000000000000000000001415 119.0
DTH2_k127_7738116_4 TIGRFAM regulatory protein, FmdB - - - 0.0000000000004391 72.0
DTH2_k127_7752920_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001414 265.0
DTH2_k127_7752920_1 TIGRFAM TonB family protein K03646,K03832 - - 0.0000008651 59.0
DTH2_k127_7762446_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 564.0
DTH2_k127_7762446_1 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 346.0
DTH2_k127_7762446_2 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000197 168.0
DTH2_k127_7762446_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000006932 166.0
DTH2_k127_7762446_4 - - - - 0.0000000000000003432 87.0
DTH2_k127_7762446_5 Ankyrin repeat - - - 0.00001575 55.0
DTH2_k127_7773888_0 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004926 277.0
DTH2_k127_7773888_1 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001245 252.0
DTH2_k127_7773888_2 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000012 228.0
DTH2_k127_7773888_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000002123 216.0
DTH2_k127_7773888_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04112,K20026,K20627,K20904 - 1.3.7.8,4.2.1.157,4.2.1.167,4.2.1.54 0.00000000000000000000000000002288 130.0
DTH2_k127_7773888_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K02574 - - 0.00000000000000000000253 102.0
DTH2_k127_7788854_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.32e-283 891.0
DTH2_k127_7788854_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 470.0
DTH2_k127_7788854_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 394.0
DTH2_k127_7788854_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 308.0
DTH2_k127_7806238_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 356.0
DTH2_k127_7806238_1 pilus assembly protein K02662 - - 0.000000000000159 74.0
DTH2_k127_7806238_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00003726 47.0
DTH2_k127_7807904_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 496.0
DTH2_k127_7807904_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 408.0
DTH2_k127_7807904_10 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.0000000000000000000000000009318 119.0
DTH2_k127_7807904_11 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000555 109.0
DTH2_k127_7807904_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000004299 102.0
DTH2_k127_7807904_13 YMGG-like Gly-zipper - - - 0.00000000000000000000007569 98.0
DTH2_k127_7807904_14 Predicted RNA-binding protein - - - 0.000000000000000000001557 94.0
DTH2_k127_7807904_15 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000004982 77.0
DTH2_k127_7807904_16 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000005194 74.0
DTH2_k127_7807904_17 - - - - 0.00002287 46.0
DTH2_k127_7807904_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000002366 246.0
DTH2_k127_7807904_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000001547 213.0
DTH2_k127_7807904_4 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000001245 208.0
DTH2_k127_7807904_5 Domain of unknown function (DUF3842) - - - 0.00000000000000000000000000000000000000000000000001416 183.0
DTH2_k127_7807904_6 - - - - 0.00000000000000000000000000000000001711 139.0
DTH2_k127_7807904_7 Glutathione peroxidase - - - 0.00000000000000000000000000000001703 133.0
DTH2_k127_7807904_8 Transcriptional regulator, MerR family - - - 0.00000000000000000000000000000003028 130.0
DTH2_k127_7807904_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000003902 136.0
DTH2_k127_7815435_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1050.0
DTH2_k127_7816683_0 PUA-like domain K00958 - 2.7.7.4 4.17e-229 724.0
DTH2_k127_7816683_1 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 576.0
DTH2_k127_7816683_2 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 430.0
DTH2_k127_7816683_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000006006 244.0
DTH2_k127_7816683_4 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000003513 163.0
DTH2_k127_7816683_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007935 104.0
DTH2_k127_7816683_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000006405 91.0
DTH2_k127_7816683_7 Protein of unknown function (DUF507) - - - 0.000000000000000001174 93.0
DTH2_k127_7816683_8 Protein of unknown function (DUF507) - - - 0.00000000000000003192 87.0
DTH2_k127_7832159_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 392.0
DTH2_k127_7832159_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 324.0
DTH2_k127_7833340_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
DTH2_k127_7849971_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 394.0
DTH2_k127_7849971_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 267.0
DTH2_k127_7849971_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001429 241.0
DTH2_k127_7849971_3 - - - - 0.000000000000000002002 89.0
DTH2_k127_7849971_4 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000001638 84.0
DTH2_k127_7854958_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 408.0
DTH2_k127_7854958_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000614 109.0
DTH2_k127_7854958_2 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000008438 61.0
DTH2_k127_7857120_0 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 363.0
DTH2_k127_7857120_1 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002172 312.0
DTH2_k127_7857120_2 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000002292 241.0
DTH2_k127_7882412_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000004234 226.0
DTH2_k127_7882412_1 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000001236 132.0
DTH2_k127_7882412_2 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000007997 82.0
DTH2_k127_7904637_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 8.445e-275 855.0
DTH2_k127_7904637_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002029 183.0
DTH2_k127_7913541_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 549.0
DTH2_k127_7913541_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 448.0
DTH2_k127_7913541_2 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001231 282.0
DTH2_k127_7913541_3 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000005577 244.0
DTH2_k127_7913541_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000005532 226.0
DTH2_k127_7913541_5 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000001119 192.0
DTH2_k127_7913541_6 - - - - 0.00000000000000000000000000000000001848 139.0
DTH2_k127_7913541_7 Protein of unknown function (DUF1566) - - - 0.00000000000002089 76.0
DTH2_k127_7913541_8 peptidyl-tyrosine sulfation - - - 0.00009331 53.0
DTH2_k127_7921989_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K00174 - 1.2.7.11,1.2.7.3 1.669e-206 660.0
DTH2_k127_7921989_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 331.0
DTH2_k127_7921989_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
DTH2_k127_7921989_3 - - - - 0.00000000000000000235 85.0
DTH2_k127_7921989_4 peptidyl-tyrosine sulfation - - - 0.0000000000000257 79.0
DTH2_k127_7921989_5 Response regulator, receiver - - - 0.000005945 49.0
DTH2_k127_7939828_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 353.0
DTH2_k127_7939828_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 308.0
DTH2_k127_7939828_2 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000005459 179.0
DTH2_k127_7939828_3 Glycoprotease family - - - 0.0000000000000000000000000000000000000000006461 168.0
DTH2_k127_7939828_4 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000001692 147.0
DTH2_k127_7939828_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000009912 107.0
DTH2_k127_7939828_6 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000414 61.0
DTH2_k127_7955993_0 Cytidylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
DTH2_k127_7955993_1 Hydrolase - - - 0.00000000000000000000000000000000000001713 153.0
DTH2_k127_7955993_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.00000000000000000000009056 104.0
DTH2_k127_7957530_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 321.0
DTH2_k127_7957530_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005093 257.0
DTH2_k127_7957530_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000008187 217.0
DTH2_k127_7957530_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000002967 154.0
DTH2_k127_7957530_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000004943 88.0
DTH2_k127_7958621_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000008749 183.0
DTH2_k127_7958621_1 phosphorelay sensor kinase activity K03320,K03406,K03407,K07315 - 2.7.13.3,3.1.3.3 0.0000000002722 71.0
DTH2_k127_7973808_0 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
DTH2_k127_7973808_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000006843 221.0
DTH2_k127_7973808_2 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000002476 139.0
DTH2_k127_798911_0 Sulfatase K01130 - 3.1.6.1 4.945e-299 920.0
DTH2_k127_7997012_0 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 345.0
DTH2_k127_7997012_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000001893 147.0
DTH2_k127_7997012_2 COGs COG3629 DNA-binding transcriptional activator of the SARP family - - - 0.0007204 44.0
DTH2_k127_7998962_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 507.0
DTH2_k127_7998962_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 346.0
DTH2_k127_7998962_10 May be involved in recombination - - - 0.0000000000000000000000000005238 119.0
DTH2_k127_7998962_11 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000002561 114.0
DTH2_k127_7998962_12 Two component signalling adaptor domain K03408 - - 0.0000000000000000000022 104.0
DTH2_k127_7998962_13 Putative exonuclease, RdgC - - - 0.0000000000001313 78.0
DTH2_k127_7998962_14 Tetratricopeptide repeat - - - 0.0000000000005166 82.0
DTH2_k127_7998962_15 Protein of unknown function (DUF1189) - - - 0.00000007401 64.0
DTH2_k127_7998962_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004488 305.0
DTH2_k127_7998962_3 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001932 276.0
DTH2_k127_7998962_4 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008916 276.0
DTH2_k127_7998962_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000001055 185.0
DTH2_k127_7998962_6 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000003865 159.0
DTH2_k127_7998962_7 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000005205 153.0
DTH2_k127_7998962_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000006679 171.0
DTH2_k127_7998962_9 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000005047 159.0
DTH2_k127_8042522_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 594.0
DTH2_k127_8042522_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 528.0
DTH2_k127_8042522_2 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 298.0
DTH2_k127_8042522_3 - - - - 0.0000000000000000000000000543 113.0
DTH2_k127_8042522_4 DNA recombination K03546,K03631 - - 0.000000000000000000001067 109.0
DTH2_k127_8042522_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000002011 68.0
DTH2_k127_8050237_0 Seven times multi-haem cytochrome CxxCH - - - 3.289e-221 691.0
DTH2_k127_8050237_1 Histidine kinase K19616 - 2.7.13.3 7.935e-203 643.0
DTH2_k127_8050237_2 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 570.0
DTH2_k127_8050237_3 PFAM CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 371.0
DTH2_k127_8050237_4 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 374.0
DTH2_k127_8050237_5 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000572 216.0
DTH2_k127_8071215_0 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
DTH2_k127_8071215_1 Sporulation initiation inhibitor K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000002507 208.0
DTH2_k127_8071215_2 UPF0761 membrane protein K07058 - - 0.0000000000002637 78.0
DTH2_k127_8073046_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 544.0
DTH2_k127_8073046_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 400.0
DTH2_k127_8073046_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 284.0
DTH2_k127_8073046_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000003202 111.0
DTH2_k127_811360_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 312.0
DTH2_k127_8124602_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1060.0
DTH2_k127_8124602_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 346.0
DTH2_k127_8124602_2 AIR synthase related protein, C-terminal domain K00946 - 2.7.4.16 0.000000000000000000000000003837 118.0
DTH2_k127_8124602_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000001081 73.0
DTH2_k127_8143398_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.427e-284 887.0
DTH2_k127_8143398_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.73e-208 666.0
DTH2_k127_8143398_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 389.0
DTH2_k127_8143398_3 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.00000000000000000000000000000000007761 142.0
DTH2_k127_8143398_4 Aldo/keto reductase family - - - 0.00000000000000000000001303 102.0
DTH2_k127_8143398_5 Tetratricopeptide repeat - - - 0.00000000000000000001438 93.0
DTH2_k127_8143398_6 - - - - 0.0000000000271 66.0
DTH2_k127_8150511_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000005031 250.0
DTH2_k127_8150511_1 Bacterial regulatory protein, Fis family K02481 - - 0.00000000000000000000000000002166 124.0
DTH2_k127_8158727_0 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 308.0
DTH2_k127_8158727_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 303.0
DTH2_k127_8158727_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000001673 88.0
DTH2_k127_8172568_0 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 539.0
DTH2_k127_8172568_1 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 360.0
DTH2_k127_8172568_2 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 329.0
DTH2_k127_8172568_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 267.0
DTH2_k127_8172568_4 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000001459 233.0
DTH2_k127_8172568_5 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000003716 234.0
DTH2_k127_8172568_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000004672 214.0
DTH2_k127_8172568_7 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000005787 190.0
DTH2_k127_8172568_8 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000002966 110.0
DTH2_k127_8172568_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000007751 87.0
DTH2_k127_8175877_0 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 415.0
DTH2_k127_8175877_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000002003 181.0
DTH2_k127_8175877_2 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000001436 167.0
DTH2_k127_8220381_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 332.0
DTH2_k127_8220381_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.000000000000000000000000000000000004166 144.0
DTH2_k127_8289864_0 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000008889 193.0
DTH2_k127_8289864_1 Flagellar Motor Protein K02557 - - 0.00000000000000000000000000000000000619 145.0
DTH2_k127_8289864_2 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000002757 137.0
DTH2_k127_8289864_3 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000000000002403 89.0
DTH2_k127_8368709_0 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 331.0
DTH2_k127_8368709_1 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000008929 217.0
DTH2_k127_8368709_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000006198 192.0
DTH2_k127_8368709_3 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000003361 53.0
DTH2_k127_8404044_0 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000002002 179.0
DTH2_k127_8404044_1 histidine kinase HAMP region domain protein K03406 - - 0.0000001071 63.0
DTH2_k127_842090_0 TIGRFAM potassium uptake protein, TrkH family K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 445.0
DTH2_k127_842090_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 256.0
DTH2_k127_842090_2 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000002706 215.0
DTH2_k127_842090_3 CGGC - - - 0.000000000000000000000000000000000002364 141.0
DTH2_k127_842090_4 - - - - 0.000000000000000000000000000000001029 135.0
DTH2_k127_842090_5 Transposase IS200 like K07491 - - 0.00000000000000000000003446 109.0
DTH2_k127_8465726_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1478.0
DTH2_k127_8467_0 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 415.0
DTH2_k127_8467_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000004447 193.0
DTH2_k127_8467_2 - - - - 0.0000000000000000000000000000000000000000000007115 175.0
DTH2_k127_85551_0 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 541.0
DTH2_k127_85551_1 nuclear chromosome segregation - - - 0.00000000001078 66.0
DTH2_k127_85551_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000257 50.0
DTH2_k127_8574339_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.028e-227 722.0
DTH2_k127_8574339_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000004815 147.0
DTH2_k127_8574339_2 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000008636 71.0
DTH2_k127_8586170_0 glycolate transport K14393 - - 1.134e-221 696.0
DTH2_k127_8586170_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000003133 120.0
DTH2_k127_8586170_2 Protein of unknown function, DUF485 - - - 0.000000000000000000000001973 109.0
DTH2_k127_8592939_0 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000004636 149.0
DTH2_k127_8592939_1 Thioredoxin - - - 0.0000001149 57.0
DTH2_k127_8639915_0 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 422.0
DTH2_k127_8639915_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000544 211.0
DTH2_k127_8639915_2 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000000000001426 207.0
DTH2_k127_8652610_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 391.0
DTH2_k127_8652610_2 Chemotaxis sensory transducer K03406 - - 0.0000000000000000001601 91.0
DTH2_k127_8652610_3 Copper chaperone PCu(A)C K09796 - - 0.0000000004924 68.0
DTH2_k127_8768673_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 374.0
DTH2_k127_8768673_1 Methyltransferase domain - - - 0.000000000000000000000000000000000011 144.0
DTH2_k127_8768673_2 SMART Tetratricopeptide domain protein - - - 0.00000000000000000002349 102.0
DTH2_k127_8800580_0 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002954 275.0
DTH2_k127_8800580_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000001181 198.0
DTH2_k127_8800580_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000034 169.0
DTH2_k127_8800580_3 Putative transposase, YhgA-like - - - 0.00003397 56.0
DTH2_k127_8800580_4 Acyltransferase family - - - 0.0008417 51.0
DTH2_k127_8855952_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 540.0
DTH2_k127_8855952_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000006747 129.0
DTH2_k127_8858516_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 544.0
DTH2_k127_8858516_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 330.0
DTH2_k127_8858516_2 methyltransferase K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000002095 236.0
DTH2_k127_8858516_3 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000000001592 143.0
DTH2_k127_8858516_4 PFAM Glutaredoxin K06191 - - 0.00000000000000000000000003649 109.0
DTH2_k127_8858516_5 - - - - 0.00000000000000000000008047 100.0
DTH2_k127_8858516_6 - - - - 0.000000004335 58.0
DTH2_k127_8858516_7 DsrE/DsrF-like family - - - 0.000002733 55.0
DTH2_k127_8858516_9 Transposase, Mutator family - - - 0.0001233 46.0
DTH2_k127_8876586_0 Methyl-accepting chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 375.0
DTH2_k127_8876586_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000001018 199.0
DTH2_k127_8876586_2 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000001653 114.0
DTH2_k127_8876586_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000008941 59.0
DTH2_k127_8882451_0 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 377.0
DTH2_k127_8882451_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 336.0
DTH2_k127_8882451_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004291 293.0
DTH2_k127_8882451_3 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000004174 193.0
DTH2_k127_888902_0 Pfam Anion-transporting ATPase K01551 - 3.6.3.16 1.719e-217 691.0
DTH2_k127_888902_1 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 565.0
DTH2_k127_888902_2 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000001269 214.0
DTH2_k127_888902_3 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000006868 146.0
DTH2_k127_888902_4 Thioredoxin K03671 - - 0.0000000000000000000000009477 107.0
DTH2_k127_888902_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000009985 104.0
DTH2_k127_888902_6 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000003471 103.0
DTH2_k127_888902_7 Transcriptional regulator K03892,K21903 - - 0.0000000000000000000001354 102.0
DTH2_k127_8900334_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 421.0
DTH2_k127_8900334_1 lipopolysaccharide core region biosynthetic process K12981 GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0005941 48.0
DTH2_k127_8904556_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1018.0
DTH2_k127_8904556_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 466.0
DTH2_k127_8904556_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000224 223.0
DTH2_k127_8904556_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000002115 218.0
DTH2_k127_8904556_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000005133 167.0
DTH2_k127_8904556_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001312 120.0
DTH2_k127_8904556_6 Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - 0.000000000000006146 78.0
DTH2_k127_8918361_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 428.0
DTH2_k127_8918361_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002196 277.0
DTH2_k127_8918361_10 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000002442 81.0
DTH2_k127_8918361_11 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000002352 66.0
DTH2_k127_8918361_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000001297 234.0
DTH2_k127_8918361_3 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000000009845 190.0
DTH2_k127_8918361_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000006054 146.0
DTH2_k127_8918361_8 - - - - 0.0000000000002026 73.0
DTH2_k127_8918361_9 protein secretion K03116,K03117 - - 0.0000000000002157 74.0
DTH2_k127_8921502_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 505.0
DTH2_k127_8921532_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 5.392e-196 626.0
DTH2_k127_8921532_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000209 185.0
DTH2_k127_8921819_0 FAD binding domain K00278 - 1.4.3.16 7.086e-195 623.0
DTH2_k127_8921819_1 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 457.0
DTH2_k127_8921819_2 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 338.0
DTH2_k127_8921819_3 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 292.0
DTH2_k127_8921819_4 PFAM Cytochrome b5 - - - 0.0000000000000000000000000006295 117.0
DTH2_k127_8921819_5 Rubrerythrin - - - 0.00000000001565 73.0
DTH2_k127_8921819_6 PFAM Type IV pilus assembly PilZ - - - 0.00000000002953 72.0
DTH2_k127_8921819_7 - - - - 0.00001525 53.0
DTH2_k127_8930583_0 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 276.0
DTH2_k127_8930791_0 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003584 280.0
DTH2_k127_8930791_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000004382 207.0
DTH2_k127_8930791_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000001461 143.0
DTH2_k127_8930791_3 Cytochrome c3 - - - 0.0001065 50.0
DTH2_k127_8940533_0 Protein of unknown function (DUF3604) - - - 0.0 1030.0
DTH2_k127_8940533_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 324.0
DTH2_k127_8940533_2 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 317.0
DTH2_k127_8940533_3 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 306.0
DTH2_k127_8940533_4 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002438 249.0
DTH2_k127_8940533_5 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
DTH2_k127_8940533_6 HupE / UreJ protein - - - 0.00000003899 57.0
DTH2_k127_8947472_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1638.0
DTH2_k127_8947472_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1504.0
DTH2_k127_8947472_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 317.0
DTH2_k127_8947472_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000001593 233.0
DTH2_k127_8947472_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000399 214.0
DTH2_k127_8947472_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000004743 189.0
DTH2_k127_8947472_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.00000000000000000000000000000000000002303 143.0
DTH2_k127_8947472_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000009631 123.0
DTH2_k127_8947472_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000792 74.0
DTH2_k127_8947472_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000001192 57.0
DTH2_k127_8963880_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 9.382e-237 739.0
DTH2_k127_8963880_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 308.0
DTH2_k127_8963880_2 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002086 264.0
DTH2_k127_8963880_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000005927 213.0
DTH2_k127_8963880_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000003297 96.0
DTH2_k127_8963880_5 FixH - - - 0.00000000000000002236 89.0
DTH2_k127_8963880_6 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.0000000000000000756 82.0
DTH2_k127_8963880_7 Cbb3-type cytochrome oxidase component FixQ - - - 0.00001242 49.0
DTH2_k127_8974786_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 303.0
DTH2_k127_8974786_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000896 228.0
DTH2_k127_8974786_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000001779 88.0
DTH2_k127_8992890_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 561.0
DTH2_k127_8992890_1 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 289.0
DTH2_k127_8992890_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
DTH2_k127_9000887_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 420.0
DTH2_k127_9000887_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000459 198.0
DTH2_k127_9000887_2 3-dehydroquinate dehydratase activity K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.0000000000000000000000000000545 125.0
DTH2_k127_9000887_3 - - - - 0.0000000000000003446 85.0
DTH2_k127_9019755_0 4Fe-4S dicluster domain - - - 1.544e-271 839.0
DTH2_k127_9019755_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 581.0
DTH2_k127_9019755_2 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 311.0
DTH2_k127_9019755_3 - - - - 0.0000000000000000000000000000000000000002719 153.0
DTH2_k127_9019755_4 PFAM 4Fe-4S ferredoxin - - - 0.000000000000000000001481 94.0
DTH2_k127_9027043_0 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 425.0
DTH2_k127_9027043_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 321.0
DTH2_k127_9027043_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002443 248.0
DTH2_k127_9027043_3 - - - - 0.00000000000000000000000000000000000000001057 156.0
DTH2_k127_9027043_4 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000005825 128.0
DTH2_k127_9027043_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000001979 114.0
DTH2_k127_9027043_6 hydrolase K01048 - 3.1.1.5 0.00006513 47.0
DTH2_k127_9059183_0 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 330.0
DTH2_k127_9059183_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000001224 165.0
DTH2_k127_9059183_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000001574 124.0
DTH2_k127_9059183_3 - - - - 0.0000000000000000000000002485 123.0
DTH2_k127_9059183_4 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.0000000001748 70.0
DTH2_k127_9059183_5 peptidyl-tyrosine sulfation - - - 0.00000000615 66.0
DTH2_k127_908601_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 469.0
DTH2_k127_908601_1 COGs COG4446 conserved - - - 0.00000000000000000000000000000000000000000002685 166.0
DTH2_k127_908601_2 Predicted membrane protein (DUF2214) K08983 - - 0.000000000000000000000000003609 117.0
DTH2_k127_908601_3 - - - - 0.000000000000000000001055 100.0
DTH2_k127_908601_4 RmuC family K09760 - - 0.000000000000000000003097 100.0
DTH2_k127_908601_5 Kelch motif - - - 0.000001297 55.0
DTH2_k127_9113534_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 426.0
DTH2_k127_9113534_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000303 252.0
DTH2_k127_9113534_2 membrane K08978 - - 0.000000000000000000000000000000000000000000000000004508 194.0
DTH2_k127_9113534_3 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000001542 164.0
DTH2_k127_9113534_4 ArgE DapE Acy1 family protein K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000003873 156.0
DTH2_k127_9127172_0 helicase superfamily c-terminal domain K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 440.0
DTH2_k127_9127172_1 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 0.0000006418 51.0
DTH2_k127_9136969_0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000002733 231.0
DTH2_k127_9136969_1 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
DTH2_k127_9136969_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000001644 55.0
DTH2_k127_9138408_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 544.0
DTH2_k127_9138408_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 458.0
DTH2_k127_9138408_10 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000004753 179.0
DTH2_k127_9138408_11 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000002646 164.0
DTH2_k127_9138408_12 integral membrane protein - - - 0.0000000000107 72.0
DTH2_k127_9138408_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 388.0
DTH2_k127_9138408_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 381.0
DTH2_k127_9138408_4 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 305.0
DTH2_k127_9138408_5 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
DTH2_k127_9138408_6 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005317 252.0
DTH2_k127_9138408_7 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000006962 228.0
DTH2_k127_9138408_8 - - - - 0.00000000000000000000000000000000000000000000000000000009697 207.0
DTH2_k127_9138408_9 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000001859 188.0
DTH2_k127_9146035_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 533.0
DTH2_k127_9146035_1 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000773 119.0
DTH2_k127_9150600_0 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 447.0
DTH2_k127_9150600_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000003179 214.0
DTH2_k127_9150600_2 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000461 205.0
DTH2_k127_9161268_0 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000001219 197.0
DTH2_k127_9161268_1 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000002351 180.0
DTH2_k127_9161268_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000904 119.0
DTH2_k127_9170688_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.144e-232 726.0
DTH2_k127_9170688_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000001436 217.0
DTH2_k127_9170688_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000002014 98.0
DTH2_k127_9170688_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000002121 87.0
DTH2_k127_9170688_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000001436 56.0
DTH2_k127_9175636_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000004659 194.0
DTH2_k127_9175636_1 epimerase dehydratase K01784 - 5.1.3.2 0.000000001007 65.0
DTH2_k127_9175636_2 Belongs to the P(II) protein family K04751 - - 0.000000001756 60.0
DTH2_k127_9215696_0 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 437.0
DTH2_k127_9215696_1 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 297.0
DTH2_k127_922356_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 559.0
DTH2_k127_922356_1 Omptin family - - - 0.000000000000000000000000000000000000000004232 168.0
DTH2_k127_922356_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000001092 120.0
DTH2_k127_9249450_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 547.0
DTH2_k127_9249450_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 323.0
DTH2_k127_9249450_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000001222 241.0
DTH2_k127_9249450_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000002667 190.0
DTH2_k127_9249450_4 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000001099 169.0
DTH2_k127_9249450_5 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000008049 156.0
DTH2_k127_9249450_6 - K06039,K07092 - - 0.0000000000000366 77.0
DTH2_k127_925156_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 7.871e-238 743.0
DTH2_k127_925156_1 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000001033 229.0
DTH2_k127_925156_2 Tar ligand binding domain homologue K03406 - - 0.0000000000000000000000000000000000000000000007984 189.0
DTH2_k127_925156_3 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000009934 169.0
DTH2_k127_925156_4 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000003039 168.0
DTH2_k127_925156_5 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000007237 141.0
DTH2_k127_925156_6 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000001548 129.0
DTH2_k127_9263782_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 327.0
DTH2_k127_9263782_1 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000005528 225.0
DTH2_k127_9263782_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000001193 134.0
DTH2_k127_9273464_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 289.0
DTH2_k127_9273464_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000001021 227.0
DTH2_k127_92792_0 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
DTH2_k127_92792_1 Cysteine rich repeat - - - 0.000000000000000000000000000000000000000000000003624 176.0
DTH2_k127_92792_2 PFAM Response regulator receiver domain - - - 0.000000000000000000006597 93.0
DTH2_k127_92792_3 response regulator - - - 0.000000000000000001159 91.0
DTH2_k127_9313595_0 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000002616 190.0
DTH2_k127_9313595_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000002339 187.0
DTH2_k127_9313595_2 sulfur carrier activity - - - 0.00000000000002891 75.0
DTH2_k127_9316215_0 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000001266 164.0
DTH2_k127_9316215_1 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.000000000000000000000000000000001431 135.0
DTH2_k127_933133_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 452.0
DTH2_k127_933133_1 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00001147 49.0
DTH2_k127_9333775_0 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 340.0
DTH2_k127_9370329_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 589.0
DTH2_k127_9370329_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
DTH2_k127_9370329_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000001076 149.0
DTH2_k127_9370329_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000002292 133.0
DTH2_k127_9370329_12 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000026 85.0
DTH2_k127_9370329_2 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 516.0
DTH2_k127_9370329_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 511.0
DTH2_k127_9370329_4 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 421.0
DTH2_k127_9370329_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 398.0
DTH2_k127_9370329_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004048 254.0
DTH2_k127_9370329_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000006058 198.0
DTH2_k127_9370329_8 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000001091 153.0
DTH2_k127_9370329_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000138 150.0
DTH2_k127_9370859_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 517.0
DTH2_k127_9370859_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000001309 227.0
DTH2_k127_9371106_0 TPR repeat - - - 3.182e-257 809.0
DTH2_k127_9371106_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 407.0
DTH2_k127_9371106_2 polysaccharide deacetylase K11931,K21478 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016787,GO:0016810,GO:0043170,GO:0043412,GO:0071704,GO:0098732 - 0.0000000000000000000000000000000000000000000000000000003495 205.0
DTH2_k127_9371106_3 Complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000000004241 131.0
DTH2_k127_9371106_4 UV-endonuclease UvdE K13281 - - 0.000000000000000000000000001916 113.0
DTH2_k127_9371106_5 - - - - 0.000000000000000000009636 106.0
DTH2_k127_9371106_6 Acetolactate synthase K01652 - 2.2.1.6 0.0007619 44.0
DTH2_k127_9376555_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1752.0
DTH2_k127_9376555_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1052.0
DTH2_k127_9376555_10 - - - - 0.000000000001055 69.0
DTH2_k127_9376555_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000001331 68.0
DTH2_k127_9376555_12 - - - - 0.0000000004745 62.0
DTH2_k127_9376555_13 beta-galactosidase activity K12308 - 3.2.1.23 0.000009275 52.0
DTH2_k127_9376555_2 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 568.0
DTH2_k127_9376555_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 487.0
DTH2_k127_9376555_4 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 415.0
DTH2_k127_9376555_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 338.0
DTH2_k127_9376555_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 250.0
DTH2_k127_9376555_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000001516 215.0
DTH2_k127_9376555_8 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000001444 167.0
DTH2_k127_9376555_9 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000001139 113.0
DTH2_k127_9377507_0 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 517.0
DTH2_k127_9377507_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 292.0
DTH2_k127_9386195_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.367e-220 697.0
DTH2_k127_9386195_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 334.0
DTH2_k127_9386195_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000001398 229.0
DTH2_k127_9386195_3 tigr00255 - - - 0.000000000000000000000000000000000000000000000000002106 192.0
DTH2_k127_9386195_4 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000002503 190.0
DTH2_k127_9386195_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000002064 181.0
DTH2_k127_9386195_6 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000001489 164.0
DTH2_k127_9386195_7 PFAM Carbohydrate-binding module 48 (Isoamylase N-terminal domain) - - - 0.00000000000000000000000000000000001097 139.0
DTH2_k127_9386195_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000008224 92.0
DTH2_k127_9386195_9 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.0000000000003634 78.0
DTH2_k127_941687_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.191e-262 818.0
DTH2_k127_941687_1 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 445.0
DTH2_k127_941687_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 323.0
DTH2_k127_941687_3 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000147 134.0
DTH2_k127_941687_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000001325 127.0
DTH2_k127_9448444_0 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 391.0
DTH2_k127_9448444_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000253 254.0
DTH2_k127_9448444_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000006031 66.0
DTH2_k127_9453390_0 phosphorelay signal transduction system K07713,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 431.0
DTH2_k127_9453390_1 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 387.0
DTH2_k127_9453390_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000872 242.0
DTH2_k127_9453390_3 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000002286 158.0
DTH2_k127_9453390_4 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000002679 109.0
DTH2_k127_9453390_5 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000005472 81.0
DTH2_k127_9453390_6 Tetratricopeptide repeat - - - 0.0001804 54.0
DTH2_k127_9502916_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 557.0
DTH2_k127_9502916_1 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 306.0
DTH2_k127_9502916_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000005254 240.0
DTH2_k127_9502916_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000001287 172.0
DTH2_k127_9697355_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 531.0
DTH2_k127_9697355_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000003584 175.0
DTH2_k127_9697355_2 membrane - - - 0.000000000000000000000001268 106.0
DTH2_k127_97196_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 441.0
DTH2_k127_97196_1 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 339.0
DTH2_k127_9732020_0 Glycogen debranching enzyme - - - 0.0 1180.0
DTH2_k127_9732020_1 - - - - 0.0000000000000000000000000000000001519 137.0
DTH2_k127_9743785_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000004432 192.0
DTH2_k127_9743785_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000003774 139.0
DTH2_k127_9743785_2 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000001686 86.0
DTH2_k127_9815049_0 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 3.138e-195 617.0
DTH2_k127_9815049_1 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000002361 194.0
DTH2_k127_9815049_2 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000008655 183.0
DTH2_k127_9815675_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000002764 173.0
DTH2_k127_9815675_1 OsmC-like protein K07397 - - 0.00000000000000000005142 96.0
DTH2_k127_986159_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 348.0
DTH2_k127_986159_1 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000883 201.0
DTH2_k127_9876705_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 495.0
DTH2_k127_9876705_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002294 243.0
DTH2_k127_9876705_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.0000000000000000000000000000001646 126.0
DTH2_k127_9876705_3 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.00000000000001077 80.0
DTH2_k127_99118_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 460.0
DTH2_k127_99118_1 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000003883 181.0
DTH2_k127_99118_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.00000000000000000000002277 104.0
DTH2_k127_993269_0 4Fe-4S dicluster domain - - - 6.993e-258 800.0
DTH2_k127_993269_1 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 316.0
DTH2_k127_9951542_0 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 461.0
DTH2_k127_9951542_1 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 374.0
DTH2_k127_9951542_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000853 179.0
DTH2_k127_9951542_3 4Fe-4S binding domain K00171 - 1.2.7.1 0.00000000000000000000000000000000002644 141.0