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Overview

ID MAG00771
Name DTH2_bin.32
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family GWC2-71-9
Genus SZUA-544
Species
Assembly information
Completeness (%) 60.84
Contamination (%) 0.69
GC content (%) 70.0
N50 (bp) 6,245
Genome size (bp) 1,613,424

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1556

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10015140_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.95e-244 772.0
DTH2_k127_10015140_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 292.0
DTH2_k127_10015140_2 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 266.0
DTH2_k127_10015140_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000004828 255.0
DTH2_k127_10015140_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000001048 220.0
DTH2_k127_10015140_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0006429 45.0
DTH2_k127_1004551_0 TIR domain - - - 0.000000000000000000000000000000000004177 153.0
DTH2_k127_1004551_1 Papain family cysteine protease - - - 0.00000000000000009148 93.0
DTH2_k127_10059220_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 451.0
DTH2_k127_10059220_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008008 256.0
DTH2_k127_10059220_2 S4 RNA-binding domain K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000001198 233.0
DTH2_k127_10059220_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000006543 131.0
DTH2_k127_10059220_4 Peptidase family M50 - - - 0.000000001415 61.0
DTH2_k127_116265_0 Belongs to the IlvD Edd family K01690,K22186 - 4.2.1.12,4.2.1.82 1.459e-234 739.0
DTH2_k127_1173747_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 1.717e-212 669.0
DTH2_k127_1173747_1 mannose metabolic process - - - 0.00000000000000000000000000000003203 139.0
DTH2_k127_1173747_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.0001017 54.0
DTH2_k127_1173747_3 PFAM SPFH domain Band 7 family - - - 0.0008608 51.0
DTH2_k127_1181171_0 DNA restriction-modification system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 407.0
DTH2_k127_1181171_1 - - - - 0.0000000000000000000000000000000000000000000004205 182.0
DTH2_k127_1181171_2 Putative adhesin - - - 0.00000000000000000001652 102.0
DTH2_k127_1181171_3 - - - - 0.00000002172 62.0
DTH2_k127_1199624_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 1049.0
DTH2_k127_1199624_1 metal cluster binding - - - 0.000000000001345 75.0
DTH2_k127_1282757_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 490.0
DTH2_k127_1282757_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 450.0
DTH2_k127_1282757_2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 330.0
DTH2_k127_1282757_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000001448 154.0
DTH2_k127_1282757_4 helix_turn_helix, mercury resistance - - - 0.00000000000003974 83.0
DTH2_k127_1283984_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 487.0
DTH2_k127_1283984_1 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 325.0
DTH2_k127_1283984_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 312.0
DTH2_k127_1283984_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 273.0
DTH2_k127_1283984_4 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.00000000000000000000000000000000000000003218 161.0
DTH2_k127_1283984_5 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.000000000000000000000003495 116.0
DTH2_k127_1283984_6 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.00000000000000007347 95.0
DTH2_k127_1283984_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000001402 61.0
DTH2_k127_1284899_0 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 422.0
DTH2_k127_1284899_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 422.0
DTH2_k127_1284899_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000002027 77.0
DTH2_k127_1284899_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 401.0
DTH2_k127_1284899_3 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 367.0
DTH2_k127_1284899_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001382 252.0
DTH2_k127_1284899_5 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000005208 203.0
DTH2_k127_1284899_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000319 159.0
DTH2_k127_1284899_7 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.0000000000000000000000000000000000000003595 168.0
DTH2_k127_1284899_8 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000001182 146.0
DTH2_k127_1284899_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000236 119.0
DTH2_k127_1288681_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 377.0
DTH2_k127_1288681_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 374.0
DTH2_k127_1288681_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 370.0
DTH2_k127_1288681_3 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000016 252.0
DTH2_k127_1288681_4 Polymer-forming cytoskeletal - - - 0.0001228 47.0
DTH2_k127_1293_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 397.0
DTH2_k127_1293_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
DTH2_k127_1293_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000008936 237.0
DTH2_k127_1293_3 4 iron, 4 sulfur cluster binding K02572,K02573 - - 0.00000000000000000000000000000000000001101 152.0
DTH2_k127_1293_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000007377 145.0
DTH2_k127_1293_5 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000006131 147.0
DTH2_k127_1293_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000007711 127.0
DTH2_k127_1293_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000001258 84.0
DTH2_k127_1293_8 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0004719 48.0
DTH2_k127_1313128_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 569.0
DTH2_k127_1313128_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000002424 238.0
DTH2_k127_13189_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1322.0
DTH2_k127_13189_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 509.0
DTH2_k127_13189_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 456.0
DTH2_k127_13189_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 302.0
DTH2_k127_13189_4 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000001452 219.0
DTH2_k127_13189_5 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000002908 141.0
DTH2_k127_13189_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000009691 96.0
DTH2_k127_1324983_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 447.0
DTH2_k127_1324983_1 Atp-dependent helicase - - - 0.000000000000000000000000000000007265 130.0
DTH2_k127_1324983_2 histidine kinase HAMP region domain protein K03406 - - 0.000000000000001322 91.0
DTH2_k127_1324983_3 Rdx family K07401 - - 0.0000000003246 62.0
DTH2_k127_1328160_0 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 553.0
DTH2_k127_1328160_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 391.0
DTH2_k127_1328160_2 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000003334 211.0
DTH2_k127_1328160_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000323 211.0
DTH2_k127_1328160_4 PA14 K12373 - 3.2.1.52 0.0000000000000000000000000000000004668 140.0
DTH2_k127_1329598_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.262e-246 777.0
DTH2_k127_1329598_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 363.0
DTH2_k127_1329598_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000008952 228.0
DTH2_k127_1329598_3 peptidase - - - 0.0000000000000000000000000000000000006186 145.0
DTH2_k127_1329598_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000016 147.0
DTH2_k127_1340822_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 327.0
DTH2_k127_1340822_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007108 267.0
DTH2_k127_1340822_2 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000003029 183.0
DTH2_k127_1340822_3 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000007989 169.0
DTH2_k127_1340822_4 Tetratricopeptide repeat - - - 0.00000000000000000000002731 101.0
DTH2_k127_1340822_5 - - - - 0.000000000000003404 80.0
DTH2_k127_1340822_6 PFAM PKD domain containing protein - - - 0.00002902 50.0
DTH2_k127_1340957_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 598.0
DTH2_k127_1340957_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
DTH2_k127_1340957_2 - - - - 0.00000000000000000000000000000000000000000000000000000954 205.0
DTH2_k127_1340957_3 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.0000000000000000000000000000000000000000000000000005052 193.0
DTH2_k127_1340957_4 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000003979 184.0
DTH2_k127_1340957_5 Sortilin, neurotensin receptor 3, - - - 0.0000000000000009831 88.0
DTH2_k127_1342150_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 459.0
DTH2_k127_1342150_1 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 305.0
DTH2_k127_1342150_2 Matrixin - - - 0.0000000000000000000000000000000000216 145.0
DTH2_k127_1342150_3 b-glycosidase, glycoside hydrolase family 3 protein - - - 0.0000292 51.0
DTH2_k127_1345670_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 557.0
DTH2_k127_1345670_1 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 366.0
DTH2_k127_1345670_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001767 269.0
DTH2_k127_1345670_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000001795 241.0
DTH2_k127_1345670_4 Peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000004604 211.0
DTH2_k127_1345670_5 - - - - 0.00000000000000000000000000000000000000000000000001774 188.0
DTH2_k127_1345670_6 - - - - 0.00000000000000000000000001207 112.0
DTH2_k127_1351430_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 563.0
DTH2_k127_1351430_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 353.0
DTH2_k127_1351430_2 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009757 287.0
DTH2_k127_1396101_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 441.0
DTH2_k127_1396101_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 343.0
DTH2_k127_1396101_2 secondary active sulfate transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004774 295.0
DTH2_k127_1396101_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000005329 243.0
DTH2_k127_1396101_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000002236 193.0
DTH2_k127_1396101_5 PFAM DivIVA protein K04074 - - 0.000000000000005608 85.0
DTH2_k127_1433780_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 356.0
DTH2_k127_1433780_1 - - - - 0.00000000000000000000000000000000000000000000000000000000004768 210.0
DTH2_k127_1433780_2 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000234 155.0
DTH2_k127_1439639_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 496.0
DTH2_k127_1439639_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 338.0
DTH2_k127_1439639_2 wide pore channel activity K07267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005712 298.0
DTH2_k127_1439639_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000192 181.0
DTH2_k127_1439639_4 Peptidogalycan biosysnthesis/recognition - - - 0.0000000000000000000000000002115 134.0
DTH2_k127_1439769_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 526.0
DTH2_k127_1439769_1 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 482.0
DTH2_k127_1439769_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000001039 130.0
DTH2_k127_1446289_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 373.0
DTH2_k127_1446289_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 271.0
DTH2_k127_1446289_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000004026 220.0
DTH2_k127_1446289_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000006332 169.0
DTH2_k127_1446289_4 STAS domain K04749 - - 0.000000000000000000000000000000000000000009122 158.0
DTH2_k127_1446289_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000255 137.0
DTH2_k127_1446289_6 DHH family K07462 - - 0.0000000000000000000002405 100.0
DTH2_k127_1446289_7 Histidine kinase-like ATPase domain - - - 0.000000000000000000001543 100.0
DTH2_k127_1531415_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 424.0
DTH2_k127_1531415_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000001361 96.0
DTH2_k127_1541448_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 404.0
DTH2_k127_1541448_1 FAD dependent oxidoreductase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0019752,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901564 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000001411 217.0
DTH2_k127_1541448_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000678 177.0
DTH2_k127_1541448_3 - - - - 0.0000000000000000000000000003405 123.0
DTH2_k127_1541448_4 - - - - 0.0001367 48.0
DTH2_k127_1542875_0 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 344.0
DTH2_k127_1542875_1 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000005999 201.0
DTH2_k127_1592472_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 438.0
DTH2_k127_1592472_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005054 269.0
DTH2_k127_1592472_2 lyase activity - - - 0.000008454 53.0
DTH2_k127_1609852_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 451.0
DTH2_k127_1609852_1 Transcriptional regulator K22106 - - 0.000000000002089 75.0
DTH2_k127_1609852_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000001486 65.0
DTH2_k127_1609852_3 Peptidase family S41 - - - 0.0000000002009 74.0
DTH2_k127_1609852_4 metallophosphoesterase - - - 0.00002632 53.0
DTH2_k127_1614119_0 PFAM peptidase M18 aminopeptidase I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 424.0
DTH2_k127_1614119_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 419.0
DTH2_k127_1614119_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 410.0
DTH2_k127_1614119_3 HEAT repeats - - - 0.00000000000000000000000000000000000005069 158.0
DTH2_k127_1622537_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000003278 181.0
DTH2_k127_1622537_1 ADP-ribosyl-(Dinitrogen reductase) hydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000009055 134.0
DTH2_k127_1622537_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000001327 78.0
DTH2_k127_16227_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 3.087e-207 658.0
DTH2_k127_16227_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005335 284.0
DTH2_k127_16227_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000005566 209.0
DTH2_k127_16227_3 Transcriptional regulator - - - 0.0000000000000000000000000000001463 128.0
DTH2_k127_16227_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000001254 72.0
DTH2_k127_1635068_0 Sodium:solute symporter family - - - 2.642e-228 722.0
DTH2_k127_1635068_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 404.0
DTH2_k127_1635068_2 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007005 244.0
DTH2_k127_1635068_3 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000004334 223.0
DTH2_k127_1665373_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.444e-225 736.0
DTH2_k127_1665373_1 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007692 275.0
DTH2_k127_1665373_2 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000001312 217.0
DTH2_k127_1665373_3 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000002469 213.0
DTH2_k127_1665373_4 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000000000002232 135.0
DTH2_k127_1665373_5 Sporulation related domain - - - 0.00000000000000006422 93.0
DTH2_k127_1670812_0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 488.0
DTH2_k127_1670812_1 competence protein - - - 0.000000000000000000000000000001441 130.0
DTH2_k127_1670812_2 shikimate dehydrogenase K00014 - 1.1.1.25 0.0000007004 55.0
DTH2_k127_167342_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 618.0
DTH2_k127_167342_1 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 413.0
DTH2_k127_16873_0 DALR_2 K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 526.0
DTH2_k127_16873_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001878 80.0
DTH2_k127_16873_2 - - - - 0.0000004604 56.0
DTH2_k127_1723382_0 Domain of unknown function(DUF2779) - - - 0.00000000000000000000000000000000000000000000000000000000000001592 226.0
DTH2_k127_1723382_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000001092 162.0
DTH2_k127_1723382_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000005823 118.0
DTH2_k127_1734941_0 N-Acetylmuramoyl-L-alanine amidase K01187 - 3.2.1.20 3.114e-273 870.0
DTH2_k127_1734941_1 PFAM Disulphide bond formation protein DsbB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008654 265.0
DTH2_k127_1734941_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000001674 191.0
DTH2_k127_1742857_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 403.0
DTH2_k127_1742857_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 335.0
DTH2_k127_1742857_2 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000000000000000000000000000000000002178 187.0
DTH2_k127_1742857_3 PTS system sorbose-specific iic component K02795 - - 0.0000000000000000001983 96.0
DTH2_k127_1742857_4 system, fructose subfamily IIA component K02793,K02794 - 2.7.1.191 0.00004328 51.0
DTH2_k127_1742857_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0001355 51.0
DTH2_k127_1759957_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 550.0
DTH2_k127_1759957_1 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000001181 229.0
DTH2_k127_1759957_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division K20543 - - 0.00000006674 57.0
DTH2_k127_1782605_0 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.0 1164.0
DTH2_k127_1782605_1 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000000007131 166.0
DTH2_k127_1782605_2 Acetyltransferase (GNAT) family - - - 0.0000000000001769 76.0
DTH2_k127_1798331_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 555.0
DTH2_k127_1798331_1 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 398.0
DTH2_k127_1798331_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
DTH2_k127_1798331_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
DTH2_k127_1798331_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
DTH2_k127_1798331_5 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000002154 231.0
DTH2_k127_1798331_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000003163 148.0
DTH2_k127_1798331_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000009116 101.0
DTH2_k127_1812015_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000003546 157.0
DTH2_k127_1812015_1 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000009444 143.0
DTH2_k127_1812015_2 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000001416 96.0
DTH2_k127_1812015_3 CBS domain K07182 - - 0.0000000000000003769 83.0
DTH2_k127_1812015_4 - - - - 0.0000000000007562 72.0
DTH2_k127_1831987_0 PFAM Zinc carboxypeptidase - - - 0.00000000000001466 76.0
DTH2_k127_1831987_1 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.00000000007954 73.0
DTH2_k127_1977876_0 PFAM Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000801 212.0
DTH2_k127_1977876_1 - - - - 0.0000000000000000000000000000307 124.0
DTH2_k127_1977876_2 Redoxin - - - 0.000000000000000000000006445 104.0
DTH2_k127_1977876_3 Redoxin - - - 0.0008826 50.0
DTH2_k127_2011588_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 594.0
DTH2_k127_2011588_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 385.0
DTH2_k127_2011588_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000009654 158.0
DTH2_k127_2011588_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000005044 153.0
DTH2_k127_2011588_5 protein required for cytochrome oxidase assembly K02259 - - 0.000001948 51.0
DTH2_k127_20381_0 NAD synthase K01916 - 6.3.1.5 2.291e-210 670.0
DTH2_k127_20381_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 321.0
DTH2_k127_20381_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000004691 171.0
DTH2_k127_20381_3 Belongs to the universal stress protein A family - - - 0.00000000581 69.0
DTH2_k127_2113_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 605.0
DTH2_k127_2125875_0 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 542.0
DTH2_k127_2125875_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 517.0
DTH2_k127_2125875_2 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 329.0
DTH2_k127_2125875_3 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 302.0
DTH2_k127_2125875_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000001513 212.0
DTH2_k127_2125875_5 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000002699 161.0
DTH2_k127_2125875_6 proteolysis K03665 - - 0.00008448 55.0
DTH2_k127_2125875_7 YtxH-like protein - - - 0.000778 46.0
DTH2_k127_2151478_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
DTH2_k127_2151478_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000001631 254.0
DTH2_k127_2177731_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 550.0
DTH2_k127_2177731_1 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000007511 181.0
DTH2_k127_2294007_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000001178 188.0
DTH2_k127_2294007_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000375 136.0
DTH2_k127_2294007_2 - - - - 0.000000000000000002489 86.0
DTH2_k127_2294007_3 multi-organism process K03195 - - 0.00000000000000009881 92.0
DTH2_k127_2314889_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 364.0
DTH2_k127_2314889_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 305.0
DTH2_k127_2314889_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000003919 159.0
DTH2_k127_2314889_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000002104 154.0
DTH2_k127_2314889_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000001057 101.0
DTH2_k127_2375768_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 346.0
DTH2_k127_2375768_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 316.0
DTH2_k127_2375768_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000141 299.0
DTH2_k127_2375768_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000001027 192.0
DTH2_k127_2375768_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000003133 199.0
DTH2_k127_2375768_5 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000009328 197.0
DTH2_k127_2375768_6 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000005899 157.0
DTH2_k127_2375768_7 - - - - 0.000000000000000000000005273 110.0
DTH2_k127_2375768_8 Tfp pilus assembly protein FimT - - - 0.0000000003799 67.0
DTH2_k127_2375768_9 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.0000000006386 69.0
DTH2_k127_2428083_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 343.0
DTH2_k127_2428083_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 332.0
DTH2_k127_2428083_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 297.0
DTH2_k127_2428083_3 Biotin-lipoyl like K01993 - - 0.000000000000000000000000001834 116.0
DTH2_k127_2455804_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 395.0
DTH2_k127_2455804_1 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002983 277.0
DTH2_k127_2455804_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 258.0
DTH2_k127_2455804_3 Rossmann-like domain K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000111 211.0
DTH2_k127_2455804_4 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000008087 188.0
DTH2_k127_2455804_5 PDZ DHR GLGF domain protein - - - 0.00000000000000000000001078 113.0
DTH2_k127_2455804_6 - - - - 0.000026 53.0
DTH2_k127_2455804_7 FtsX-like permease family K02004 - - 0.00003839 56.0
DTH2_k127_2500177_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 266.0
DTH2_k127_2500177_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000007851 237.0
DTH2_k127_2500177_2 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000008093 176.0
DTH2_k127_2500177_3 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000007954 153.0
DTH2_k127_2500177_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00000000000000000000000000000000000002687 153.0
DTH2_k127_2500177_5 - - - - 0.000000000000000000238 94.0
DTH2_k127_2536025_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 555.0
DTH2_k127_2536025_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 463.0
DTH2_k127_2536025_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 452.0
DTH2_k127_2536025_3 SnoaL-like domain - - - 0.00000000000000000000000001873 110.0
DTH2_k127_2536025_4 Archease protein family (MTH1598/TM1083) - - - 0.000000003353 60.0
DTH2_k127_2544606_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1080.0
DTH2_k127_2544606_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 311.0
DTH2_k127_2544606_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003958 241.0
DTH2_k127_2544606_3 Yip1 domain - - - 0.0000000006331 68.0
DTH2_k127_2552879_0 regulation of DNA-templated transcription, elongation - - - 8.159e-274 863.0
DTH2_k127_2561963_0 inositol 2-dehydrogenase activity - - - 1.592e-213 686.0
DTH2_k127_2561963_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 496.0
DTH2_k127_2561963_10 Cold shock K03704 - - 0.00000000000000000000000000000001547 131.0
DTH2_k127_2561963_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000004068 119.0
DTH2_k127_2561963_12 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000001613 103.0
DTH2_k127_2561963_13 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00007796 47.0
DTH2_k127_2561963_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 392.0
DTH2_k127_2561963_3 4Fe-4S binding domain K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 314.0
DTH2_k127_2561963_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000001122 267.0
DTH2_k127_2561963_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001506 266.0
DTH2_k127_2561963_6 COG2755 Lysophospholipase L1 and related K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000001198 249.0
DTH2_k127_2561963_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008611 246.0
DTH2_k127_2561963_8 lycopene cyclase K06443 - 5.5.1.19 0.0000000000000000000000000000000000000000000000000000000000001482 220.0
DTH2_k127_2561963_9 DoxX K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000003009 169.0
DTH2_k127_2566102_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 569.0
DTH2_k127_2566102_1 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 510.0
DTH2_k127_2566102_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 395.0
DTH2_k127_2566102_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000009014 194.0
DTH2_k127_2566102_4 phosphorelay signal transduction system K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000009754 185.0
DTH2_k127_2567549_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1883.0
DTH2_k127_2573987_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 9.791e-276 865.0
DTH2_k127_2573987_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 532.0
DTH2_k127_2573987_2 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 457.0
DTH2_k127_2573987_3 Domain of unknown function (DUF3536) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004602 255.0
DTH2_k127_2573987_4 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000002079 151.0
DTH2_k127_2573987_5 Patatin-like phospholipase K07001 - - 0.00001605 57.0
DTH2_k127_2573987_6 Patatin-like phospholipase K07001 - - 0.0003423 53.0
DTH2_k127_2580742_0 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 368.0
DTH2_k127_2580742_1 Amylo-alpha-1,6-glucosidase - - - 0.0005426 49.0
DTH2_k127_2586890_0 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 489.0
DTH2_k127_2586890_1 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 464.0
DTH2_k127_2586890_2 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.000000000000000000000000000000000000000000000000000008874 212.0
DTH2_k127_2586890_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000005581 184.0
DTH2_k127_2586890_4 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000001314 123.0
DTH2_k127_2586890_5 response regulator - - - 0.000000000000000000003885 101.0
DTH2_k127_2586890_6 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000005249 85.0
DTH2_k127_2586890_7 response regulator - - - 0.000000000000003276 79.0
DTH2_k127_2589200_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 482.0
DTH2_k127_2589200_1 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002928 279.0
DTH2_k127_2589200_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002533 276.0
DTH2_k127_2589200_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000001359 118.0
DTH2_k127_259100_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 451.0
DTH2_k127_259100_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 323.0
DTH2_k127_259100_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000001102 214.0
DTH2_k127_259100_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000001437 197.0
DTH2_k127_259100_4 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000235 128.0
DTH2_k127_2597469_0 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 448.0
DTH2_k127_2597469_1 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 374.0
DTH2_k127_2597469_2 HAMP domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 299.0
DTH2_k127_2597469_3 phosphate-selective porin O and P K07221 - - 0.0000007732 61.0
DTH2_k127_2597599_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1016.0
DTH2_k127_2597599_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 598.0
DTH2_k127_2597599_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 340.0
DTH2_k127_2597599_3 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008288 245.0
DTH2_k127_2597599_4 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
DTH2_k127_2597599_5 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000006863 184.0
DTH2_k127_2597599_6 Mazg nucleotide pyrophosphohydrolase K00800 - 2.5.1.19 0.000000000000000000000000000000005964 129.0
DTH2_k127_2597599_7 - - - - 0.000000000004007 69.0
DTH2_k127_2599940_0 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 297.0
DTH2_k127_2599940_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000484 257.0
DTH2_k127_2599940_2 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000008414 57.0
DTH2_k127_2616740_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000001715 73.0
DTH2_k127_2617263_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.000000000000000000000000000000922 137.0
DTH2_k127_2617263_1 antisigma factor binding K04749,K06378 - - 0.000000000000000000000000314 118.0
DTH2_k127_2617430_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 535.0
DTH2_k127_2617430_1 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000005 207.0
DTH2_k127_2617430_2 - - - - 0.0000000000000000003017 100.0
DTH2_k127_2617430_3 pfam abc K06857 - 3.6.3.55 0.0000000000000000004198 89.0
DTH2_k127_2621722_0 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 469.0
DTH2_k127_2621722_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 376.0
DTH2_k127_2621722_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 336.0
DTH2_k127_2621722_3 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 318.0
DTH2_k127_2621722_4 - - - - 0.000000000000000000000000003172 121.0
DTH2_k127_2621722_5 - - - - 0.000000000000000000000001465 115.0
DTH2_k127_2621722_6 Predicted membrane protein (DUF2231) - - - 0.000000000000000005049 91.0
DTH2_k127_2621722_7 PFAM blue (type 1) copper domain protein - - - 0.0000000002863 62.0
DTH2_k127_2624837_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 563.0
DTH2_k127_2641692_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 464.0
DTH2_k127_2641692_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 347.0
DTH2_k127_2641692_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001539 270.0
DTH2_k127_2641692_3 MlaD protein K02067 - - 0.00000000000000000000001209 111.0
DTH2_k127_2641692_4 - - - - 0.0000001766 56.0
DTH2_k127_2641692_5 - - - - 0.00001458 51.0
DTH2_k127_26631_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.35e-290 904.0
DTH2_k127_26631_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 355.0
DTH2_k127_26631_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 333.0
DTH2_k127_26631_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 317.0
DTH2_k127_26631_4 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 310.0
DTH2_k127_26631_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000006794 220.0
DTH2_k127_26631_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000001132 192.0
DTH2_k127_26631_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000001181 120.0
DTH2_k127_26631_8 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000006906 89.0
DTH2_k127_2687301_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 486.0
DTH2_k127_2703646_0 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 351.0
DTH2_k127_2703646_1 PFAM Ribulose bisphosphate carboxylase large K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 323.0
DTH2_k127_2703646_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000004645 115.0
DTH2_k127_2703646_3 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000003253 102.0
DTH2_k127_2730637_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 439.0
DTH2_k127_2730637_1 Ribosomal protein S2 K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
DTH2_k127_2730637_10 Biotin-requiring enzyme - - - 0.00000000000000000000000000000001173 137.0
DTH2_k127_2730637_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000001591 89.0
DTH2_k127_2730637_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 325.0
DTH2_k127_2730637_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 308.0
DTH2_k127_2730637_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000033 225.0
DTH2_k127_2730637_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000001084 224.0
DTH2_k127_2730637_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000001755 209.0
DTH2_k127_2730637_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000003348 201.0
DTH2_k127_2730637_8 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000002031 184.0
DTH2_k127_2730637_9 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000207 145.0
DTH2_k127_2733738_0 Acyclic terpene utilisation family protein AtuA - - - 4.329e-200 632.0
DTH2_k127_2733738_1 serine-type endopeptidase activity. It is involved in the biological process described with proteolysis K01280 GO:0000209,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008240,GO:0009987,GO:0010883,GO:0010884,GO:0016043,GO:0016567,GO:0016604,GO:0016787,GO:0017171,GO:0019538,GO:0022607,GO:0031974,GO:0031981,GO:0032446,GO:0032879,GO:0033218,GO:0036211,GO:0042277,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0048518,GO:0050789,GO:0051259,GO:0051260,GO:0065003,GO:0065007,GO:0065008,GO:0070011,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1905952,GO:1905954 3.4.14.10 0.00000002375 66.0
DTH2_k127_2734082_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 5.325e-228 724.0
DTH2_k127_2734082_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 540.0
DTH2_k127_2734082_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 340.0
DTH2_k127_2734082_3 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000007052 231.0
DTH2_k127_2781074_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 345.0
DTH2_k127_2781074_1 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000007081 215.0
DTH2_k127_2781074_2 protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000008538 130.0
DTH2_k127_2781074_3 - - - - 0.000000000002971 72.0
DTH2_k127_2801290_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 393.0
DTH2_k127_2801290_1 - - - - 0.00000000000000000000000000000000000002392 154.0
DTH2_k127_2801290_2 Diguanylate cyclase - - - 0.00000000000000000000000000000002834 145.0
DTH2_k127_2801290_3 Helix-turn-helix domain - - - 0.0000000000000000000866 97.0
DTH2_k127_2804184_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 422.0
DTH2_k127_2804184_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001004 234.0
DTH2_k127_2804184_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000000000002921 218.0
DTH2_k127_2804184_3 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000412 135.0
DTH2_k127_2804184_4 Permease MlaE K02066 - - 0.00000000000000000000000000003539 129.0
DTH2_k127_2804184_5 Binds the 23S rRNA K02909 - - 0.0000000000000000000000008075 106.0
DTH2_k127_2804184_6 Methyltransferase small domain K02493 - 2.1.1.297 0.0000000000000000008096 94.0
DTH2_k127_2804184_7 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000006583 92.0
DTH2_k127_2804184_8 Gaf domain - - - 0.00000000000003036 85.0
DTH2_k127_2804184_9 MlaD protein K06192 - - 0.00008356 55.0
DTH2_k127_2809933_0 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000002474 156.0
DTH2_k127_2809933_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000006695 65.0
DTH2_k127_2809933_2 Tetratricopeptide repeat - - - 0.0002116 52.0
DTH2_k127_2816558_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 487.0
DTH2_k127_2816558_1 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 381.0
DTH2_k127_2816558_10 Putative zinc-binding metallo-peptidase - - - 0.000009172 57.0
DTH2_k127_2816558_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 316.0
DTH2_k127_2816558_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001201 273.0
DTH2_k127_2816558_4 Fe-S protein K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
DTH2_k127_2816558_5 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007826 256.0
DTH2_k127_2816558_6 - - - - 0.000000000000000000000000000000001491 135.0
DTH2_k127_2816558_8 DnaJ molecular chaperone homology domain - - - 0.0000000001707 72.0
DTH2_k127_2816558_9 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.00000008907 55.0
DTH2_k127_2824665_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 590.0
DTH2_k127_2824665_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 473.0
DTH2_k127_2824665_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002019 275.0
DTH2_k127_2824665_3 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000002113 237.0
DTH2_k127_2824665_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000079 133.0
DTH2_k127_2824665_5 - - - - 0.000000000000000002051 92.0
DTH2_k127_2824665_6 - - - - 0.0009014 46.0
DTH2_k127_2883271_0 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000111 272.0
DTH2_k127_2883271_1 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000009231 286.0
DTH2_k127_2883271_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000004403 176.0
DTH2_k127_2883271_3 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000001644 167.0
DTH2_k127_2883271_4 NUDIX domain - - - 0.000000000000000000000000000000000000000001329 164.0
DTH2_k127_2883271_5 FeoA K03709 - - 0.000001116 53.0
DTH2_k127_2883271_6 Putative zinc-finger - - - 0.0003371 47.0
DTH2_k127_2883960_0 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000002302 238.0
DTH2_k127_2883960_1 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000319 235.0
DTH2_k127_2883960_2 Part of a membrane complex involved in electron transport - - - 0.0000000000000000000000000000000001222 139.0
DTH2_k127_2885274_0 esterase - - - 2.819e-269 839.0
DTH2_k127_2885274_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 492.0
DTH2_k127_2885274_2 nuclear chromosome segregation - - - 0.000000000000000000000000000001133 133.0
DTH2_k127_2896569_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 3.001e-246 783.0
DTH2_k127_2896569_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 395.0
DTH2_k127_2896569_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000001403 222.0
DTH2_k127_2896569_3 DinB family - - - 0.00000000000000000000000000000000102 141.0
DTH2_k127_2896569_4 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000001794 125.0
DTH2_k127_2896569_5 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000008954 95.0
DTH2_k127_2896569_6 glyoxalase III activity - - - 0.0000000000000000003127 96.0
DTH2_k127_2896569_7 S4 RNA-binding domain K04762 - - 0.000000000000000001947 88.0
DTH2_k127_2896569_8 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - 0.00000000000000008135 84.0
DTH2_k127_2896569_9 Belongs to the globin family - - - 0.0000003719 60.0
DTH2_k127_2997798_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 598.0
DTH2_k127_2997798_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 535.0
DTH2_k127_2997798_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 402.0
DTH2_k127_2997798_3 proline dipeptidase activity K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000001642 265.0
DTH2_k127_2997798_4 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000006921 229.0
DTH2_k127_2997798_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001327 183.0
DTH2_k127_2997798_6 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000013 179.0
DTH2_k127_2997798_7 sensor histidine kinase response - - - 0.000000000000000000004818 104.0
DTH2_k127_2997798_8 - - - - 0.000000000000000332 86.0
DTH2_k127_2997798_9 4-vinyl reductase, 4VR - - - 0.0000000000001322 84.0
DTH2_k127_3003857_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 507.0
DTH2_k127_3003857_1 Glycine cleavage T-protein C-terminal barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 494.0
DTH2_k127_3003857_2 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 447.0
DTH2_k127_3003857_3 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 366.0
DTH2_k127_303291_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 461.0
DTH2_k127_3038885_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 434.0
DTH2_k127_3038885_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 399.0
DTH2_k127_3038885_2 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 317.0
DTH2_k127_3038885_3 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
DTH2_k127_3038885_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000001844 214.0
DTH2_k127_3038885_5 Response regulator receiver - - - 0.0000000000000000000000000000000000000000005996 168.0
DTH2_k127_3038885_6 transporter antisigma-factor antagonist STAS K04749 - - 0.000000000006737 72.0
DTH2_k127_3053532_0 PglZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 546.0
DTH2_k127_3053532_1 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000002188 229.0
DTH2_k127_3092097_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 502.0
DTH2_k127_3092097_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 428.0
DTH2_k127_3092097_2 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 408.0
DTH2_k127_3092097_3 - - - - 0.000000000000000000000000000000007095 132.0
DTH2_k127_3092259_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 383.0
DTH2_k127_3092259_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 330.0
DTH2_k127_3092259_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 308.0
DTH2_k127_3092259_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 293.0
DTH2_k127_3092259_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000001932 228.0
DTH2_k127_3092259_5 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000002085 167.0
DTH2_k127_3092259_6 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000003944 151.0
DTH2_k127_3092332_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 472.0
DTH2_k127_3092332_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 447.0
DTH2_k127_3092332_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000104 257.0
DTH2_k127_3092332_3 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001811 259.0
DTH2_k127_3092332_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000000000000000007255 170.0
DTH2_k127_3092332_5 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000002969 130.0
DTH2_k127_3092332_6 Preprotein translocase SecG subunit K03075 - - 0.000000000000002943 80.0
DTH2_k127_3114853_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 1.726e-269 839.0
DTH2_k127_3114853_1 ABC transporter, ATP-binding protein - - - 0.0000000000000000000008259 100.0
DTH2_k127_3114853_2 - - - - 0.000000000000000000002895 96.0
DTH2_k127_3119621_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 444.0
DTH2_k127_3119621_1 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000006926 160.0
DTH2_k127_3119621_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000309 153.0
DTH2_k127_3139757_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.625e-245 765.0
DTH2_k127_3139757_1 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000001096 81.0
DTH2_k127_3150077_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 420.0
DTH2_k127_3150077_1 SURF1 family K14998 - - 0.0000000000000000000000000000000002263 144.0
DTH2_k127_3150077_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000005516 131.0
DTH2_k127_3150077_3 GYD domain - - - 0.000000000000000000000000000000004933 129.0
DTH2_k127_3150077_4 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01761 - 4.4.1.11 0.00000000000000000000000000000007049 125.0
DTH2_k127_3150077_5 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000008093 104.0
DTH2_k127_3231353_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1081.0
DTH2_k127_3231353_1 protein secretion K21449 - - 0.0000000000000000000000000001561 121.0
DTH2_k127_3231353_2 Elongation factor SelB, winged helix K03833 - - 0.00000000002194 72.0
DTH2_k127_3252112_0 4Fe-4S single cluster domain K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 306.0
DTH2_k127_3252112_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000007873 213.0
DTH2_k127_3278442_0 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000002265 163.0
DTH2_k127_3278442_1 Alg9-like mannosyltransferase family - - - 0.0000000000000000000000003026 117.0
DTH2_k127_3278442_2 Putative bacterial sensory transduction regulator - - - 0.00000000008365 69.0
DTH2_k127_3353436_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1116.0
DTH2_k127_3353436_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.54e-230 743.0
DTH2_k127_3353436_10 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000000002166 149.0
DTH2_k127_3353436_11 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.0000000000000000000000000000000001197 136.0
DTH2_k127_3353436_12 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.00000000000000000000004081 107.0
DTH2_k127_3353436_13 - - - - 0.000000000000000000001468 96.0
DTH2_k127_3353436_14 Heavy-metal-associated domain K07213 - - 0.000000000001952 71.0
DTH2_k127_3353436_15 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000009117 75.0
DTH2_k127_3353436_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 2.235e-218 683.0
DTH2_k127_3353436_3 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 515.0
DTH2_k127_3353436_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 440.0
DTH2_k127_3353436_5 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 435.0
DTH2_k127_3353436_6 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 319.0
DTH2_k127_3353436_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 307.0
DTH2_k127_3353436_8 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009415 259.0
DTH2_k127_3353436_9 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000005318 170.0
DTH2_k127_335878_0 Participates in both transcription termination and antitermination K02600 - - 4.401e-203 641.0
DTH2_k127_335878_1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 561.0
DTH2_k127_335878_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 513.0
DTH2_k127_335878_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 478.0
DTH2_k127_335878_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 449.0
DTH2_k127_335878_5 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 366.0
DTH2_k127_335878_6 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000001147 163.0
DTH2_k127_335878_7 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000373 108.0
DTH2_k127_335878_8 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.00000000001785 68.0
DTH2_k127_335878_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000005829 66.0
DTH2_k127_3361416_0 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 7.242e-226 729.0
DTH2_k127_3361416_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 519.0
DTH2_k127_3361416_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 488.0
DTH2_k127_3361416_3 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 374.0
DTH2_k127_3361416_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000002528 250.0
DTH2_k127_3361416_5 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000001156 115.0
DTH2_k127_3361416_6 Protein of unknown function, DUF481 K07283 - - 0.0005898 51.0
DTH2_k127_3447200_0 PFAM peptidase M6, immune inhibitor A - - - 0.00000000000000000000000000000000000000000342 173.0
DTH2_k127_3495362_0 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 375.0
DTH2_k127_3503183_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 421.0
DTH2_k127_3503183_1 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000057 237.0
DTH2_k127_3521232_0 lysine biosynthetic process via aminoadipic acid - - - 1.332e-238 766.0
DTH2_k127_3521232_1 protein kinase activity - - - 1.623e-213 693.0
DTH2_k127_3521232_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000938 52.0
DTH2_k127_352803_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 441.0
DTH2_k127_352803_1 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009596 268.0
DTH2_k127_352803_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000001749 83.0
DTH2_k127_3532406_0 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 353.0
DTH2_k127_3532406_1 Cytochrome c K00376,K02305,K17760 - 1.1.9.1,1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
DTH2_k127_3532406_2 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000005869 168.0
DTH2_k127_3577583_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005651 283.0
DTH2_k127_3577583_1 - - - - 0.000000000000000000000000000000000378 147.0
DTH2_k127_3577583_2 DinB superfamily - - - 0.00000000006855 69.0
DTH2_k127_3607109_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 517.0
DTH2_k127_3607109_1 Belongs to the GcvT family K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 453.0
DTH2_k127_3607109_2 Sarcosine oxidase, subunit beta K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 424.0
DTH2_k127_3607109_3 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 322.0
DTH2_k127_3607109_4 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000000008038 164.0
DTH2_k127_3607109_5 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.0000000000001 74.0
DTH2_k127_3607109_6 Protein of unknown function (DUF3103) - - - 0.00003114 56.0
DTH2_k127_3669345_0 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005415 265.0
DTH2_k127_3669345_1 - - - - 0.0000000001089 75.0
DTH2_k127_375249_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 4.505e-239 751.0
DTH2_k127_375249_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 317.0
DTH2_k127_375249_2 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000158 275.0
DTH2_k127_375249_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000313 272.0
DTH2_k127_375249_4 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001909 267.0
DTH2_k127_375249_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000226 217.0
DTH2_k127_375249_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000002527 189.0
DTH2_k127_375249_7 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000001606 140.0
DTH2_k127_375249_8 - - - - 0.0000001807 55.0
DTH2_k127_3801869_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 437.0
DTH2_k127_382505_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.055e-220 709.0
DTH2_k127_382505_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 547.0
DTH2_k127_382505_2 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000368 134.0
DTH2_k127_382505_3 Ftsk_gamma K03466 - - 0.00000000000000004842 81.0
DTH2_k127_382505_4 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000002368 72.0
DTH2_k127_3844296_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 601.0
DTH2_k127_3844296_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 328.0
DTH2_k127_3844296_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000147 201.0
DTH2_k127_3844296_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000007276 183.0
DTH2_k127_3844296_4 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000000000004293 148.0
DTH2_k127_3844296_5 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000001166 126.0
DTH2_k127_3844296_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.00000000000000000000000000003341 131.0
DTH2_k127_3844296_7 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000006662 98.0
DTH2_k127_3844296_8 LysM domain - - - 0.00000000000004153 85.0
DTH2_k127_3850082_0 Elongation factor G, domain IV K02355 - - 1.282e-271 852.0
DTH2_k127_3850082_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000005677 182.0
DTH2_k127_3850082_2 of the major facilitator superfamily K08151 - - 0.000001651 55.0
DTH2_k127_3907768_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 366.0
DTH2_k127_3907768_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 327.0
DTH2_k127_3907768_2 - - - - 0.000000000000000000386 92.0
DTH2_k127_3913815_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 520.0
DTH2_k127_3913815_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 427.0
DTH2_k127_3913815_2 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000006384 203.0
DTH2_k127_3913815_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000006297 194.0
DTH2_k127_3913815_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000001743 164.0
DTH2_k127_3913815_5 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000183 162.0
DTH2_k127_3913815_6 cytochrome c - - - 0.0000000000000000003807 94.0
DTH2_k127_3913815_7 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000007005 68.0
DTH2_k127_3913815_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00000003916 61.0
DTH2_k127_3928064_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 451.0
DTH2_k127_3928064_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002244 273.0
DTH2_k127_3928064_2 Major Facilitator Superfamily - - - 0.00000000000000000000003646 106.0
DTH2_k127_3933283_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.722e-213 666.0
DTH2_k127_3933283_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 486.0
DTH2_k127_3933283_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 440.0
DTH2_k127_3933283_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 433.0
DTH2_k127_3933283_4 Phosphopantetheine attachment site - - - 0.00000000000001075 85.0
DTH2_k127_3957803_0 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 586.0
DTH2_k127_3957803_1 Zn-dependent protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 368.0
DTH2_k127_3957803_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 338.0
DTH2_k127_3957803_3 component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 295.0
DTH2_k127_3957803_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000002944 154.0
DTH2_k127_3957803_5 Rhomboid family - - - 0.0000000000000000000000000000000001001 145.0
DTH2_k127_3957803_6 Pterin 4 alpha carbinolamine dehydratase K01724,K11991 - 3.5.4.33,4.2.1.96 0.000000000000000000000000000000006647 131.0
DTH2_k127_3957803_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000002117 100.0
DTH2_k127_3957803_8 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00001581 48.0
DTH2_k127_3979517_0 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 321.0
DTH2_k127_3979517_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 321.0
DTH2_k127_3979517_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 311.0
DTH2_k127_3979517_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001122 214.0
DTH2_k127_3979517_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000004814 173.0
DTH2_k127_3979517_5 Glycosyl transferase family 2 K08301 - - 0.00000000000000000000000000000000000000001925 164.0
DTH2_k127_3979517_6 - - - - 0.000000000000000004067 91.0
DTH2_k127_3979517_7 sterol carrier protein - - - 0.000000000000551 79.0
DTH2_k127_4003023_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 467.0
DTH2_k127_4003023_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000001711 128.0
DTH2_k127_4013069_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 565.0
DTH2_k127_4013069_1 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 573.0
DTH2_k127_4013069_2 Beta-eliminating lyase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 473.0
DTH2_k127_4013069_3 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 417.0
DTH2_k127_4013069_4 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000001379 189.0
DTH2_k127_4013069_5 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000397 181.0
DTH2_k127_4101844_0 Aldehyde dehydrogenase family K22187 - - 1.337e-216 677.0
DTH2_k127_4101844_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000002726 261.0
DTH2_k127_4101844_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000816 215.0
DTH2_k127_4109235_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 3.546e-216 684.0
DTH2_k127_4109235_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 498.0
DTH2_k127_4109235_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 300.0
DTH2_k127_4110343_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0 1027.0
DTH2_k127_4110343_1 tRNA synthetases class I (M) K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 533.0
DTH2_k127_4110343_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 441.0
DTH2_k127_4110343_3 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 341.0
DTH2_k127_4110343_4 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000002026 195.0
DTH2_k127_4110343_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000001294 158.0
DTH2_k127_4110343_6 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000002675 115.0
DTH2_k127_4110343_7 - - - - 0.0000000000001047 79.0
DTH2_k127_4110343_8 Pfam:SusD - - - 0.000000009192 57.0
DTH2_k127_4112349_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005561 252.0
DTH2_k127_4112349_1 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000005008 168.0
DTH2_k127_4112349_2 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000005253 148.0
DTH2_k127_4168200_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 1.06e-252 803.0
DTH2_k127_4168200_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 359.0
DTH2_k127_4168200_10 SnoaL-like domain - - - 0.00000001005 66.0
DTH2_k127_4168200_2 extracellular solute-binding protein, family 1 K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002259 276.0
DTH2_k127_4168200_3 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000004226 234.0
DTH2_k127_4168200_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000003283 216.0
DTH2_k127_4168200_5 PFAM Inosine uridine-preferring nucleoside hydrolase K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000003637 204.0
DTH2_k127_4168200_6 3-hydroxyacyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000001055 205.0
DTH2_k127_4168200_7 cell redox homeostasis - - - 0.0000000000000000007071 101.0
DTH2_k127_4168200_8 HlyD family secretion protein K02005 - - 0.0000000000000001681 93.0
DTH2_k127_4168200_9 Putative phosphatase (DUF442) - - - 0.000000000007508 75.0
DTH2_k127_4172335_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 426.0
DTH2_k127_4172335_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 358.0
DTH2_k127_4172335_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000001598 145.0
DTH2_k127_4172335_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000004577 149.0
DTH2_k127_4172335_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000004706 145.0
DTH2_k127_4172335_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000008624 134.0
DTH2_k127_4172335_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000009039 106.0
DTH2_k127_4172335_15 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000008041 94.0
DTH2_k127_4172335_16 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001678 96.0
DTH2_k127_4172335_17 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002873 95.0
DTH2_k127_4172335_18 Ribosomal L29 protein K02904 - - 0.0000001401 57.0
DTH2_k127_4172335_2 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
DTH2_k127_4172335_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001487 253.0
DTH2_k127_4172335_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003124 253.0
DTH2_k127_4172335_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000008862 232.0
DTH2_k127_4172335_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000008714 206.0
DTH2_k127_4172335_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000003424 203.0
DTH2_k127_4172335_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000001462 184.0
DTH2_k127_4172335_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000003564 152.0
DTH2_k127_4227547_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 386.0
DTH2_k127_4227547_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 313.0
DTH2_k127_4227547_2 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000003038 147.0
DTH2_k127_4227547_3 amino acid K03294 - - 0.0000002 52.0
DTH2_k127_4227547_4 Domain of Unknown Function (DUF350) - - - 0.00001324 50.0
DTH2_k127_4251343_0 response to heat K03695,K03696,K03697,K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 340.0
DTH2_k127_4251343_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
DTH2_k127_4251343_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000103 220.0
DTH2_k127_4251343_3 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000000000000000001441 180.0
DTH2_k127_4251343_4 - - - - 0.000000000001126 72.0
DTH2_k127_4280253_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 1.071e-276 869.0
DTH2_k127_4280253_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.125e-215 683.0
DTH2_k127_4280253_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 437.0
DTH2_k127_4280253_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 292.0
DTH2_k127_4280253_4 Zn-dependent protease - - - 0.00005027 53.0
DTH2_k127_4363784_0 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001902 234.0
DTH2_k127_4363784_1 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000001264 169.0
DTH2_k127_4363784_2 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000003522 107.0
DTH2_k127_4363784_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000002157 54.0
DTH2_k127_441120_0 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000003129 244.0
DTH2_k127_441120_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000001017 194.0
DTH2_k127_441120_2 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000003846 187.0
DTH2_k127_44770_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 575.0
DTH2_k127_44770_1 Peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.00000000000000000000000000000000000002332 151.0
DTH2_k127_44770_2 Lipopolysaccharide-assembly - - - 0.000000000000000000003563 100.0
DTH2_k127_44770_3 - - - - 0.00009358 55.0
DTH2_k127_452404_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.456e-232 740.0
DTH2_k127_452404_1 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 403.0
DTH2_k127_452404_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.000000002365 59.0
DTH2_k127_4537705_0 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 391.0
DTH2_k127_4537705_1 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001653 253.0
DTH2_k127_4539226_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 542.0
DTH2_k127_4539226_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 498.0
DTH2_k127_4539226_2 PFAM Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 452.0
DTH2_k127_4539226_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 292.0
DTH2_k127_4539226_4 transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000509 237.0
DTH2_k127_4539226_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000002592 172.0
DTH2_k127_4539226_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000001391 180.0
DTH2_k127_4539226_7 Late embryogenesis abundant protein - - - 0.00000000000000000007159 99.0
DTH2_k127_45401_0 Phenazine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002896 276.0
DTH2_k127_45401_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000001168 194.0
DTH2_k127_45401_2 - - - - 0.0000000000000000000006203 106.0
DTH2_k127_45401_3 EamA-like transporter family K03298 - - 0.00000002167 65.0
DTH2_k127_45401_4 - - - - 0.0000004815 62.0
DTH2_k127_4605379_0 Protein export membrane protein - - - 0.0 1337.0
DTH2_k127_4605379_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 322.0
DTH2_k127_461895_0 argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 504.0
DTH2_k127_461895_1 Regulates arginine biosynthesis genes K03402 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000002822 106.0
DTH2_k127_466973_0 Formate dehydrogenase alpha subunit K00123,K05299 - 1.17.1.10,1.17.1.9 6.505e-241 785.0
DTH2_k127_466973_1 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 442.0
DTH2_k127_466973_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000002701 203.0
DTH2_k127_466973_3 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000004465 166.0
DTH2_k127_466973_4 - - - - 0.000000000000000000000000000000005759 145.0
DTH2_k127_466973_5 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000000000000000001015 111.0
DTH2_k127_4672856_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 531.0
DTH2_k127_4672856_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000004575 186.0
DTH2_k127_4675727_0 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 398.0
DTH2_k127_4675727_1 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000003939 179.0
DTH2_k127_4675727_2 Nodulation efficiency protein D - - - 0.000000000000000000002848 109.0
DTH2_k127_4730224_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 464.0
DTH2_k127_4730224_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 270.0
DTH2_k127_4730224_2 - - - - 0.00000000000000000000000000000000004687 138.0
DTH2_k127_4730224_3 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000001423 119.0
DTH2_k127_4738324_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 557.0
DTH2_k127_4738324_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 467.0
DTH2_k127_4738324_2 Cell division protein FtsQ K03589 - - 0.0000000000000000000000008262 115.0
DTH2_k127_4738324_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000003556 57.0
DTH2_k127_4764960_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.448e-212 679.0
DTH2_k127_4764960_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002793 281.0
DTH2_k127_4764960_2 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000068 217.0
DTH2_k127_4764960_3 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000212 209.0
DTH2_k127_4764960_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000001861 169.0
DTH2_k127_4764960_5 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.000000000000000000000000005248 114.0
DTH2_k127_4764960_6 Two component signalling adaptor domain K03408 - - 0.000000002825 65.0
DTH2_k127_4813022_0 Bacterial regulatory protein, Fis family - - - 9.97e-204 649.0
DTH2_k127_4813022_1 PAS domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001834 225.0
DTH2_k127_4854190_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 520.0
DTH2_k127_4854190_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000007312 192.0
DTH2_k127_4924552_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 565.0
DTH2_k127_4924552_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 524.0
DTH2_k127_4924552_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 392.0
DTH2_k127_4924552_3 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000295 181.0
DTH2_k127_4924552_4 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000205 183.0
DTH2_k127_4924552_5 Cytochrome c - - - 0.000000000000000000000000000000000006199 150.0
DTH2_k127_4924552_6 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000001235 99.0
DTH2_k127_5055575_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 460.0
DTH2_k127_5055575_1 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 375.0
DTH2_k127_5055575_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 289.0
DTH2_k127_5055575_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000786 250.0
DTH2_k127_5055575_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000155 219.0
DTH2_k127_5055575_5 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.000000000000000000001296 98.0
DTH2_k127_5055575_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000006811 99.0
DTH2_k127_5070162_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.222e-203 642.0
DTH2_k127_5070162_1 Domain of unknown function (DUF5118) - - - 4.115e-203 672.0
DTH2_k127_5070162_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 584.0
DTH2_k127_5070162_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
DTH2_k127_5070162_4 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 327.0
DTH2_k127_5070162_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 300.0
DTH2_k127_5070162_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 286.0
DTH2_k127_5070162_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000302 241.0
DTH2_k127_5070162_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000002266 246.0
DTH2_k127_5070162_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000004049 134.0
DTH2_k127_5070884_0 cellular manganese ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 395.0
DTH2_k127_5070884_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000006835 165.0
DTH2_k127_5070884_2 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.00000000000000000000000000000005079 128.0
DTH2_k127_5091650_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 471.0
DTH2_k127_5091650_1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.0000000000000000000000003239 118.0
DTH2_k127_509820_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000002226 99.0
DTH2_k127_509820_1 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000008208 95.0
DTH2_k127_509820_2 DNA-templated transcription, initiation - - - 0.00004129 48.0
DTH2_k127_5114506_0 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 441.0
DTH2_k127_5114506_1 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000008827 169.0
DTH2_k127_5136142_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.324e-285 905.0
DTH2_k127_5136142_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 357.0
DTH2_k127_5136142_3 Belongs to the protein kinase superfamily - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004675,GO:0004888,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019199,GO:0019538,GO:0023052,GO:0036211,GO:0038023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.0009318 47.0
DTH2_k127_517009_0 aminopeptidase activity K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000003776 244.0
DTH2_k127_5181090_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 495.0
DTH2_k127_5181090_1 domain protein K13735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 339.0
DTH2_k127_5181090_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 338.0
DTH2_k127_5181090_3 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000207 252.0
DTH2_k127_5181090_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000003933 228.0
DTH2_k127_5181090_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000004798 139.0
DTH2_k127_5210208_0 oligopeptide transporter, OPT family - - - 2.433e-218 712.0
DTH2_k127_5210208_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001069 252.0
DTH2_k127_5210208_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000029 242.0
DTH2_k127_5210208_3 Belongs to the 5'-nucleotidase family - - - 0.0000000000000000000000000000000000000002075 171.0
DTH2_k127_5210208_4 antibiotic catabolic process - - - 0.00000000000000000000000003546 125.0
DTH2_k127_5210208_5 - - - - 0.00000000000000000001161 96.0
DTH2_k127_5221378_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.73e-229 739.0
DTH2_k127_5221378_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 534.0
DTH2_k127_5221378_10 PFAM BioY protein K03523 - - 0.000000000000000000000005729 117.0
DTH2_k127_5221378_11 CAAX protease self-immunity K07052 - - 0.00000000000000000000005907 113.0
DTH2_k127_5221378_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000001606 83.0
DTH2_k127_5221378_13 Outer membrane protein beta-barrel domain - - - 0.00000001196 67.0
DTH2_k127_5221378_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 524.0
DTH2_k127_5221378_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 486.0
DTH2_k127_5221378_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 452.0
DTH2_k127_5221378_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 404.0
DTH2_k127_5221378_6 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 347.0
DTH2_k127_5221378_7 - - - - 0.000000000000000000000000000000000000000000000000000000001559 216.0
DTH2_k127_5221378_8 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000009059 209.0
DTH2_k127_5221378_9 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000009519 126.0
DTH2_k127_5224669_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 451.0
DTH2_k127_5224669_1 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 359.0
DTH2_k127_5224669_2 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000001745 74.0
DTH2_k127_5224669_3 ATPase activity K02013 - 3.6.3.34 0.00001934 48.0
DTH2_k127_5242382_0 Heat shock 70 kDa protein K04043 - - 1.13e-314 975.0
DTH2_k127_5242382_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 8.221e-266 829.0
DTH2_k127_5242382_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 401.0
DTH2_k127_5242382_3 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 392.0
DTH2_k127_5242382_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003913 273.0
DTH2_k127_5242382_5 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000301 266.0
DTH2_k127_5242382_6 COGs COG1845 Heme copper-type cytochrome quinol oxidase subunit 3 K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000004885 243.0
DTH2_k127_5242382_7 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000001617 91.0
DTH2_k127_5242382_8 Protein of unknown function, DUF481 - - - 0.00000000001249 74.0
DTH2_k127_5242382_9 - - - - 0.0009196 50.0
DTH2_k127_52917_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 501.0
DTH2_k127_52917_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000001254 139.0
DTH2_k127_52917_2 - - - - 0.0000000000000000000000005103 114.0
DTH2_k127_5309152_0 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 494.0
DTH2_k127_5309152_1 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000003117 221.0
DTH2_k127_5309152_2 transferase activity, transferring glycosyl groups K00713,K06338 - - 0.00000000000000000000000000000000000000000000000000712 198.0
DTH2_k127_5309152_3 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000005118 190.0
DTH2_k127_5309152_4 4Fe-4S single cluster domain K07001 - - 0.0002065 44.0
DTH2_k127_5318138_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 460.0
DTH2_k127_5318138_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003327 278.0
DTH2_k127_5321813_0 lysine biosynthetic process via aminoadipic acid - - - 3.576e-273 860.0
DTH2_k127_5321813_1 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 481.0
DTH2_k127_5321813_2 Mn2 and Fe2 transporters of the NRAMP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 431.0
DTH2_k127_5321813_3 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005156 282.0
DTH2_k127_5329395_0 Bacterial dnaA protein K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 426.0
DTH2_k127_5329395_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 326.0
DTH2_k127_5329395_2 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002486 277.0
DTH2_k127_5329395_3 PFAM Roadblock LC7 family protein - - - 0.000001349 57.0
DTH2_k127_5333383_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 512.0
DTH2_k127_5333383_1 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 428.0
DTH2_k127_5333383_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 421.0
DTH2_k127_5333383_3 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 420.0
DTH2_k127_5333383_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
DTH2_k127_5333383_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 372.0
DTH2_k127_5333383_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 366.0
DTH2_k127_5333383_7 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 264.0
DTH2_k127_5333383_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000001734 224.0
DTH2_k127_5333383_9 TPR repeat-containing protein - - - 0.00006586 55.0
DTH2_k127_5371881_0 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000000000000000000006021 218.0
DTH2_k127_5371881_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000004814 85.0
DTH2_k127_5371881_2 PFAM Rieske 2Fe-2S domain protein K02636 - 1.10.9.1 0.00000109 58.0
DTH2_k127_5403610_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.757e-297 921.0
DTH2_k127_5403610_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000859 162.0
DTH2_k127_5403610_2 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000761 111.0
DTH2_k127_5403610_4 - - - - 0.000000000000006414 85.0
DTH2_k127_5438234_0 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000002095 77.0
DTH2_k127_5452280_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002767 289.0
DTH2_k127_5452280_1 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002213 243.0
DTH2_k127_5452280_2 Forkhead associated domain - - - 0.00000000000002991 76.0
DTH2_k127_547803_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 513.0
DTH2_k127_547803_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 389.0
DTH2_k127_547803_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 389.0
DTH2_k127_547803_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 381.0
DTH2_k127_547803_4 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 354.0
DTH2_k127_547803_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 361.0
DTH2_k127_547803_6 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007195 256.0
DTH2_k127_5483314_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 323.0
DTH2_k127_5483314_1 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000002198 104.0
DTH2_k127_5483314_2 ATPase activity K16923 - - 0.0000000000000000000002669 112.0
DTH2_k127_5483314_3 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000001139 98.0
DTH2_k127_5483314_4 cobalt transport K16785 - - 0.00000000000004438 81.0
DTH2_k127_5555996_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 532.0
DTH2_k127_5555996_1 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 376.0
DTH2_k127_5555996_2 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
DTH2_k127_5578158_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 563.0
DTH2_k127_5578158_1 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 508.0
DTH2_k127_5578158_10 Glycosyl transferases group 1 - - - 0.000000000003363 71.0
DTH2_k127_5578158_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 382.0
DTH2_k127_5578158_3 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 358.0
DTH2_k127_5578158_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 323.0
DTH2_k127_5578158_5 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000001552 197.0
DTH2_k127_5578158_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000002594 146.0
DTH2_k127_5578158_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000001333 93.0
DTH2_k127_5578158_8 Regulatory protein, FmdB family - - - 0.000000000000000148 83.0
DTH2_k127_5578158_9 MacB-like periplasmic core domain - - - 0.000000000000004976 85.0
DTH2_k127_5583286_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 472.0
DTH2_k127_5583286_1 lytic transglycosylase activity K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000005963 141.0
DTH2_k127_558567_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000007859 243.0
DTH2_k127_558567_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000168 181.0
DTH2_k127_558567_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.000000000000000000000000000000000000000006012 166.0
DTH2_k127_558567_3 Preprotein translocase subunit K03210 - - 0.00000000000001044 83.0
DTH2_k127_5626547_0 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 347.0
DTH2_k127_5626547_1 Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 322.0
DTH2_k127_5626547_2 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000001048 217.0
DTH2_k127_5626547_3 HAD-hyrolase-like K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000006493 202.0
DTH2_k127_563211_0 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 563.0
DTH2_k127_563211_1 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 349.0
DTH2_k127_563211_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 337.0
DTH2_k127_563211_3 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 281.0
DTH2_k127_563211_4 subunit of a heme lyase K02200 - - 0.000000000000000000000000001218 122.0
DTH2_k127_563211_5 - - - - 0.0000000000000000000001826 103.0
DTH2_k127_563211_6 PFAM transglutaminase domain protein - - - 0.00000000000007826 74.0
DTH2_k127_5743414_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 389.0
DTH2_k127_5743414_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004246 264.0
DTH2_k127_5743414_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000007569 98.0
DTH2_k127_5745540_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.624e-250 784.0
DTH2_k127_5745540_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 364.0
DTH2_k127_5745540_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 338.0
DTH2_k127_5794891_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000008447 106.0
DTH2_k127_5794891_1 Pathogenicity locus - - - 0.0000000000000000000001366 108.0
DTH2_k127_5823278_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.852e-216 682.0
DTH2_k127_5823278_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660 - - 0.0000001318 62.0
DTH2_k127_5912771_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 607.0
DTH2_k127_5912771_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 492.0
DTH2_k127_5912771_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 405.0
DTH2_k127_5912771_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 381.0
DTH2_k127_5912771_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000005216 174.0
DTH2_k127_5912771_5 MoaE protein K03635 - 2.8.1.12 0.0000000000001388 71.0
DTH2_k127_5916344_0 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 450.0
DTH2_k127_5916344_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000002545 117.0
DTH2_k127_6026908_0 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
DTH2_k127_6026908_1 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000009705 123.0
DTH2_k127_6026908_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000005519 115.0
DTH2_k127_6090437_0 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001277 283.0
DTH2_k127_6090437_1 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000002989 223.0
DTH2_k127_6165036_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 456.0
DTH2_k127_6165036_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000001839 62.0
DTH2_k127_616830_0 Glycogen debranching enzyme - - - 5.003e-265 843.0
DTH2_k127_616830_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000001665 180.0
DTH2_k127_616830_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000002418 183.0
DTH2_k127_616830_3 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000006908 128.0
DTH2_k127_616830_4 Bacterial Ig-like domain 2 - - - 0.0000000000000000004771 99.0
DTH2_k127_616830_5 SnoaL-like domain - - - 0.000000000000000001373 93.0
DTH2_k127_6270456_0 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 448.0
DTH2_k127_6270456_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 396.0
DTH2_k127_6270456_10 - - - - 0.0000001228 61.0
DTH2_k127_6270456_2 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 372.0
DTH2_k127_6270456_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 347.0
DTH2_k127_6270456_4 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000003753 239.0
DTH2_k127_6270456_5 Multidrug resistance protein K11741,K18924 - - 0.0000000000000000000000000000000000016 147.0
DTH2_k127_6270456_6 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000329 147.0
DTH2_k127_6270456_7 DinB superfamily - - - 0.000000000000000000000000000000000679 138.0
DTH2_k127_6270456_8 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000004872 96.0
DTH2_k127_6293349_0 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 429.0
DTH2_k127_6293349_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000004219 238.0
DTH2_k127_6293349_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000000000000000003813 226.0
DTH2_k127_6293349_3 PFAM Cysteine-rich secretory protein family - - - 0.000000000000000000000000000005272 123.0
DTH2_k127_6293349_4 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000007493 126.0
DTH2_k127_6340150_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 9.653e-297 925.0
DTH2_k127_6340150_1 Hsp70 protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 586.0
DTH2_k127_6340150_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000006026 167.0
DTH2_k127_6340150_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000003833 118.0
DTH2_k127_6340150_12 Polysaccharide deacetylase - - - 0.000000000000000000000000001033 124.0
DTH2_k127_6340150_13 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000364 114.0
DTH2_k127_6340150_14 Protein of unknown function DUF89 K09116 - - 0.00000002616 59.0
DTH2_k127_6340150_15 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000006804 55.0
DTH2_k127_6340150_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 576.0
DTH2_k127_6340150_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 539.0
DTH2_k127_6340150_4 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 464.0
DTH2_k127_6340150_5 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 455.0
DTH2_k127_6340150_6 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 422.0
DTH2_k127_6340150_7 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000002938 276.0
DTH2_k127_6340150_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004479 267.0
DTH2_k127_6340150_9 rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000002314 192.0
DTH2_k127_6346840_0 AMIN domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 466.0
DTH2_k127_6346840_1 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 429.0
DTH2_k127_6346840_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 404.0
DTH2_k127_6346840_3 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000002694 138.0
DTH2_k127_6346840_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000001599 108.0
DTH2_k127_6346840_5 - - - - 0.000000000000000000001607 100.0
DTH2_k127_6346840_6 - - - - 0.00000000000000000001846 100.0
DTH2_k127_6346840_7 Pilus assembly protein PilO K02664 - - 0.000000002539 66.0
DTH2_k127_6348181_0 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 474.0
DTH2_k127_6348181_1 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 433.0
DTH2_k127_6348181_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 319.0
DTH2_k127_6348181_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000002026 216.0
DTH2_k127_6348181_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000009568 151.0
DTH2_k127_6348181_5 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000001414 151.0
DTH2_k127_6348181_6 Bacterial Ig-like domain (group 1) - - - 0.00000000000000000006526 106.0
DTH2_k127_6348181_7 - - - - 0.000000001263 69.0
DTH2_k127_6354785_0 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 323.0
DTH2_k127_6354785_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007567 276.0
DTH2_k127_6354785_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000006364 217.0
DTH2_k127_6354785_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000001569 193.0
DTH2_k127_6357730_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1628.0
DTH2_k127_6357730_1 Outer membrane protein beta-barrel domain - - - 0.0000000002552 70.0
DTH2_k127_6357730_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000001233 61.0
DTH2_k127_6357730_3 Antibiotic biosynthesis monooxygenase - - - 0.000000001566 64.0
DTH2_k127_6374532_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 553.0
DTH2_k127_6374532_1 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000001125 207.0
DTH2_k127_6374532_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000003839 126.0
DTH2_k127_6384579_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 565.0
DTH2_k127_6384579_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000001576 203.0
DTH2_k127_6384579_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000006999 135.0
DTH2_k127_6404182_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 548.0
DTH2_k127_6404182_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 355.0
DTH2_k127_6404182_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 329.0
DTH2_k127_6404182_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 324.0
DTH2_k127_6404182_4 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000106 256.0
DTH2_k127_6404182_5 histone H2A K63-linked ubiquitination K03220 - - 0.00000000000000000009553 104.0
DTH2_k127_6404182_6 Periplasmic or secreted lipoprotein - - - 0.00000000004201 71.0
DTH2_k127_6407627_0 membrane organization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 623.0
DTH2_k127_6407627_1 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 308.0
DTH2_k127_6407627_2 ATP:ADP antiporter activity K01932,K03301 - - 0.000000000000000000000000000000000000001138 154.0
DTH2_k127_6407627_3 Calcineurin-like phosphoesterase - - - 0.0000000000003197 75.0
DTH2_k127_6429681_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.772e-278 865.0
DTH2_k127_6429681_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.194e-262 815.0
DTH2_k127_6429681_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 563.0
DTH2_k127_6429681_3 Cytidylate kinase-like family K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000111 152.0
DTH2_k127_6429681_4 Protein conserved in bacteria - - - 0.000001448 59.0
DTH2_k127_6434086_0 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 369.0
DTH2_k127_6434086_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000002896 134.0
DTH2_k127_6443871_0 Atp-dependent helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 364.0
DTH2_k127_6443871_1 Thioesterase superfamily K07107 - - 0.00000000000000000000001288 106.0
DTH2_k127_6443871_2 Bacterial regulatory proteins, tetR family - - - 0.0000006915 57.0
DTH2_k127_6443871_3 Positively regulates the dhaKLM operon from a sigma-70 promoter K05880 GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000008996 57.0
DTH2_k127_6449877_0 PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 539.0
DTH2_k127_6449877_2 PFAM OsmC-like protein K04063 - - 0.00000001766 57.0
DTH2_k127_6477689_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 380.0
DTH2_k127_6477689_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004866 270.0
DTH2_k127_6477689_2 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000005833 184.0
DTH2_k127_6499396_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 326.0
DTH2_k127_6499396_1 Glycosyl transferase family 39 - - - 0.00000000000000000000000008509 121.0
DTH2_k127_6503433_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.488e-237 745.0
DTH2_k127_6503433_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 534.0
DTH2_k127_6503433_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 346.0
DTH2_k127_6503433_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000002073 231.0
DTH2_k127_6503433_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000007289 197.0
DTH2_k127_6503433_5 'Cold-shock' DNA-binding domain - - - 0.00000000000000000000000000000000000000001248 160.0
DTH2_k127_6503433_6 GYD domain - - - 0.00000000000000000000000000000000001646 138.0
DTH2_k127_6503433_7 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000272 98.0
DTH2_k127_6503433_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000552 74.0
DTH2_k127_6537402_0 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 596.0
DTH2_k127_6537402_1 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 578.0
DTH2_k127_6537402_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 509.0
DTH2_k127_6537402_3 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 340.0
DTH2_k127_6537402_4 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 319.0
DTH2_k127_6537402_5 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000002967 263.0
DTH2_k127_6537402_6 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000001578 250.0
DTH2_k127_6557139_0 AcrB/AcrD/AcrF family K03296 - - 4.244e-308 975.0
DTH2_k127_6557139_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000001756 195.0
DTH2_k127_6557139_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000003285 162.0
DTH2_k127_6557139_3 Bacterial regulatory proteins, tetR family - - - 0.00001857 51.0
DTH2_k127_6589772_0 protein kinase activity - - - 6.223e-232 753.0
DTH2_k127_6589772_1 protein kinase activity - - - 7.016e-197 643.0
DTH2_k127_6589772_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 576.0
DTH2_k127_6589772_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 550.0
DTH2_k127_6589772_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 545.0
DTH2_k127_6589772_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 410.0
DTH2_k127_6589772_6 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 382.0
DTH2_k127_6589772_7 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000001017 150.0
DTH2_k127_6589772_8 PIN domain - - - 0.0000000000000221 79.0
DTH2_k127_6589772_9 Alcohol dehydrogenase GroES domain protein K00001,K13953 - 1.1.1.1 0.0000005779 55.0
DTH2_k127_6676354_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000005002 163.0
DTH2_k127_6676354_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000008576 126.0
DTH2_k127_6676354_2 Putative zinc ribbon domain - - - 0.000000001202 65.0
DTH2_k127_6707830_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 599.0
DTH2_k127_6707830_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 409.0
DTH2_k127_6707830_2 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 401.0
DTH2_k127_6707830_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 366.0
DTH2_k127_6707830_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 317.0
DTH2_k127_6707830_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000001176 180.0
DTH2_k127_6707830_6 Short-chain dehydrogenase reductase SDR K00059,K11610 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000007705 181.0
DTH2_k127_6707830_7 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000005881 138.0
DTH2_k127_6757668_0 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 355.0
DTH2_k127_6757668_1 ABC1 family K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 287.0
DTH2_k127_6757668_2 Anion-transporting ATPase - - - 0.0000000000000000000000000000000000000000000001431 179.0
DTH2_k127_6757668_3 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000008375 83.0
DTH2_k127_6757668_4 Poly(hydroxyalcanoate) granule associated protein - - - 0.00000000000003931 79.0
DTH2_k127_677251_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 290.0
DTH2_k127_677251_1 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004369 269.0
DTH2_k127_677251_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007807 245.0
DTH2_k127_6791462_0 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 378.0
DTH2_k127_6791462_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 323.0
DTH2_k127_6791462_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
DTH2_k127_6808275_0 Cupredoxin-like domain K00376 - 1.7.2.4 2.792e-275 859.0
DTH2_k127_6808275_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 575.0
DTH2_k127_6808275_2 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001929 271.0
DTH2_k127_6808275_3 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001181 248.0
DTH2_k127_6808275_4 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000433 175.0
DTH2_k127_6808275_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000001728 145.0
DTH2_k127_6808275_6 Cytochrome c - - - 0.00000000000000001084 89.0
DTH2_k127_6808525_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 426.0
DTH2_k127_6808525_1 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000002069 173.0
DTH2_k127_6808525_2 curli production assembly transport component CsgG K04087 - - 0.0000000000000000000000000000000000000000000117 180.0
DTH2_k127_6808525_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000354 119.0
DTH2_k127_6808525_4 - - - - 0.00000000000000000000001808 114.0
DTH2_k127_6812702_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 445.0
DTH2_k127_6812702_1 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 334.0
DTH2_k127_6812702_2 Endoribonuclease L-PSP - - - 0.000000000000005789 82.0
DTH2_k127_6850107_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 436.0
DTH2_k127_6850107_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 343.0
DTH2_k127_6850107_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 346.0
DTH2_k127_6850107_3 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.00000000000000000000000000000000000000000000000000000003182 218.0
DTH2_k127_6850107_4 NDK K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000003376 172.0
DTH2_k127_6850107_5 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000005839 145.0
DTH2_k127_6850107_6 Ribosomal L32p protein family K02911 - - 0.000000000000000004221 86.0
DTH2_k127_6850107_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000005108 79.0
DTH2_k127_6928261_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 348.0
DTH2_k127_6928261_1 Forkhead associated domain - - - 0.000004605 53.0
DTH2_k127_6932603_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 4.389e-257 803.0
DTH2_k127_6932603_1 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 573.0
DTH2_k127_6932603_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 468.0
DTH2_k127_6932603_3 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 353.0
DTH2_k127_6932603_4 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002631 278.0
DTH2_k127_6932603_5 Aerotolerance regulator N-terminal - - - 0.000001343 60.0
DTH2_k127_694565_0 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000005375 248.0
DTH2_k127_694565_1 Outer membrane efflux protein K12340 - - 0.0000000000000000000000009959 113.0
DTH2_k127_6950916_0 Carboxypeptidase regulatory-like domain - - - 0.0000001829 55.0
DTH2_k127_6950916_1 Bacterial Ig-like domain 2 - - - 0.000002906 59.0
DTH2_k127_6951357_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009247 257.0
DTH2_k127_69792_0 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 370.0
DTH2_k127_69792_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000004944 149.0
DTH2_k127_69792_2 COGs COG2151 metal-sulfur cluster biosynthetic protein - - - 0.0000000000000000000000165 103.0
DTH2_k127_69792_3 Phenylacetic acid degradation B - - - 0.000000000000001959 78.0
DTH2_k127_69792_4 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.00000000001112 69.0
DTH2_k127_6990453_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 332.0
DTH2_k127_6990453_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004213 274.0
DTH2_k127_6990453_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000664 231.0
DTH2_k127_6990453_3 - - - - 0.000000000000008844 79.0
DTH2_k127_7009796_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 578.0
DTH2_k127_7009796_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 365.0
DTH2_k127_7009796_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000008542 245.0
DTH2_k127_7009796_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000006447 188.0
DTH2_k127_7009796_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000004374 181.0
DTH2_k127_7009796_5 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000005821 137.0
DTH2_k127_7009796_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.00000000000000006615 83.0
DTH2_k127_7059842_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 378.0
DTH2_k127_7059842_1 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 287.0
DTH2_k127_7059842_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000003007 167.0
DTH2_k127_7059842_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000012 126.0
DTH2_k127_7092125_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 366.0
DTH2_k127_7092125_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000001064 109.0
DTH2_k127_7092125_2 SnoaL-like domain - - - 0.0000002454 63.0
DTH2_k127_7120014_0 hydroxymethylglutaryl-CoA reductase (NADPH) activity K00021 - 1.1.1.34 1.247e-226 713.0
DTH2_k127_7120014_1 Cysteine synthase cystathionine beta-synthase family protein K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 436.0
DTH2_k127_7120014_2 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 400.0
DTH2_k127_7120014_3 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000001346 193.0
DTH2_k127_7120014_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000001024 170.0
DTH2_k127_7120014_5 SMART Transport-associated and nodulation region K04065 - - 0.000000000000000000000000000002899 129.0
DTH2_k127_7120785_0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.00000000000000000000000000000000000000000003744 163.0
DTH2_k127_7120785_1 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000001226 164.0
DTH2_k127_7120785_2 O-methyltransferase activity - - - 0.00000000000000000002874 101.0
DTH2_k127_7150207_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000002334 168.0
DTH2_k127_7163953_0 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 329.0
DTH2_k127_7163953_1 Major facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000004847 201.0
DTH2_k127_7191544_0 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000001066 228.0
DTH2_k127_7191544_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000001486 144.0
DTH2_k127_7191544_2 Membrane - - - 0.0000000000000000634 87.0
DTH2_k127_7191544_3 GAF domain-containing protein K08968 - 1.8.4.14 0.00000001187 57.0
DTH2_k127_7318476_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000001883 190.0
DTH2_k127_7318476_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001021 158.0
DTH2_k127_7318476_2 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.00000000000000000005006 91.0
DTH2_k127_7344549_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 472.0
DTH2_k127_7344549_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000003736 180.0
DTH2_k127_7370643_0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 359.0
DTH2_k127_7370643_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000003134 227.0
DTH2_k127_7370643_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000009727 130.0
DTH2_k127_7370643_3 - - - - 0.000000000000000000002371 99.0
DTH2_k127_7370643_4 Redoxin K03564 - 1.11.1.15 0.00000000000002483 76.0
DTH2_k127_7370643_5 Redoxin K03564 - 1.11.1.15 0.00001168 51.0
DTH2_k127_7400301_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 409.0
DTH2_k127_7400301_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000004534 139.0
DTH2_k127_7439875_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 3.252e-239 751.0
DTH2_k127_7439875_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 452.0
DTH2_k127_7439875_2 HypF finger K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009952 287.0
DTH2_k127_7439875_3 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000003051 221.0
DTH2_k127_7439875_4 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000002611 198.0
DTH2_k127_7439875_5 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000005672 142.0
DTH2_k127_7439875_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0001674 47.0
DTH2_k127_7487499_0 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 552.0
DTH2_k127_7487499_1 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000001224 176.0
DTH2_k127_7487499_2 Putative adhesin - - - 0.0000000000002661 81.0
DTH2_k127_7515436_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 7.396e-219 688.0
DTH2_k127_7515436_1 COG0348 Polyferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009212 291.0
DTH2_k127_7515436_2 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
DTH2_k127_7515436_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000005225 244.0
DTH2_k127_7515436_4 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.000000000000000000000000000000815 132.0
DTH2_k127_7515436_5 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.00000000000000000000000000001152 132.0
DTH2_k127_7515436_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000002582 112.0
DTH2_k127_7598471_0 Rhodanese Homology Domain K01069,K03797 - 3.1.2.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 577.0
DTH2_k127_7598471_1 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 359.0
DTH2_k127_7598471_2 PFAM Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 346.0
DTH2_k127_7598471_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000001716 235.0
DTH2_k127_7598471_4 Export-related chaperone CsaA K06878 - - 0.0000000000000000000000000000000000008498 147.0
DTH2_k127_7598471_5 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000357 107.0
DTH2_k127_7598471_6 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.000000000000000002189 88.0
DTH2_k127_7598471_7 - - - - 0.00004194 54.0
DTH2_k127_7603828_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000001096 188.0
DTH2_k127_7603828_1 GAF domain - - - 0.0000000000000000000000000000000000000000001551 172.0
DTH2_k127_7603828_2 ZIP Zinc transporter K07238 - - 0.000000000000003992 76.0
DTH2_k127_7603828_3 AMP binding - - - 0.00000000007103 75.0
DTH2_k127_7603828_4 ABC-2 family transporter protein K01992,K19341 - - 0.00000009266 61.0
DTH2_k127_7603828_5 BON domain - - - 0.00007174 55.0
DTH2_k127_7613868_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
DTH2_k127_7613868_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000001297 180.0
DTH2_k127_7613868_2 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000002225 157.0
DTH2_k127_7613868_3 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000006749 81.0
DTH2_k127_7624781_0 siderophore transport K02014 - - 1.592e-207 673.0
DTH2_k127_7624781_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 580.0
DTH2_k127_7624781_10 SH3 domain - - - 0.00008898 53.0
DTH2_k127_7624781_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 473.0
DTH2_k127_7624781_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001997 260.0
DTH2_k127_7624781_4 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004683 261.0
DTH2_k127_7624781_5 Predicted membrane protein (DUF2177) - - - 0.00000000000000000000000000000000001328 140.0
DTH2_k127_7624781_6 OsmC-like protein - - - 0.000000000000000000000000000000001529 138.0
DTH2_k127_7624781_7 PFAM glycosyl transferase family 9 - - - 0.00000000000000000000004336 103.0
DTH2_k127_7624781_8 - - - - 0.000000000000000000333 93.0
DTH2_k127_7624781_9 - - - - 0.00001787 54.0
DTH2_k127_7658517_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 3.045e-265 837.0
DTH2_k127_7658517_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 473.0
DTH2_k127_7658517_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000000000000000000000000000000000000000000000874 185.0
DTH2_k127_7658517_3 - - - - 0.000000000000000000000000000000000001187 145.0
DTH2_k127_7659633_0 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
DTH2_k127_7659633_1 ZIP Zinc transporter - - - 0.000000000000000000000000000000000000000000000006899 181.0
DTH2_k127_7659633_2 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000004262 149.0
DTH2_k127_7659633_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000381 146.0
DTH2_k127_7659633_4 Dodecin K09165 - - 0.0000000000001466 79.0
DTH2_k127_7711435_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 457.0
DTH2_k127_7713001_0 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 372.0
DTH2_k127_7713001_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000008022 93.0
DTH2_k127_7713001_2 Cysteine-rich secretory protein family - - - 0.0000000002319 65.0
DTH2_k127_7713001_3 Hemerythrin HHE cation binding domain - - - 0.00005286 53.0
DTH2_k127_7765354_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 438.0
DTH2_k127_7765354_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002848 289.0
DTH2_k127_7765354_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000009856 215.0
DTH2_k127_7765354_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000001689 177.0
DTH2_k127_7870978_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 606.0
DTH2_k127_7870978_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 321.0
DTH2_k127_7870978_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000007075 210.0
DTH2_k127_7874792_0 cellulose binding - - - 0.0 1177.0
DTH2_k127_7874792_1 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009946 480.0
DTH2_k127_7874792_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000001508 186.0
DTH2_k127_7874792_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000001389 175.0
DTH2_k127_7905584_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 2.57e-253 790.0
DTH2_k127_7905584_1 Carboxyl transferase domain - - - 8.527e-232 728.0
DTH2_k127_7905584_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 369.0
DTH2_k127_7905584_3 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 352.0
DTH2_k127_7905584_4 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000001549 224.0
DTH2_k127_7905584_5 Hemolysins and related proteins containing CBS domains - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000007824 168.0
DTH2_k127_7905584_6 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000009982 169.0
DTH2_k127_7905584_7 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000004453 137.0
DTH2_k127_7985062_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000001779 117.0
DTH2_k127_7985062_2 DinB superfamily - - - 0.000000000000006509 76.0
DTH2_k127_7987897_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 8.449e-249 788.0
DTH2_k127_7987897_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 606.0
DTH2_k127_7987897_2 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 532.0
DTH2_k127_7987897_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 350.0
DTH2_k127_7987897_4 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001315 302.0
DTH2_k127_7987897_5 Participates in the control of copper homeostasis K06201 - - 0.000000000000000000000000000000000000000000000000000000000000000000006029 250.0
DTH2_k127_7987897_6 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001745 208.0
DTH2_k127_7990556_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 615.0
DTH2_k127_7990556_1 secondary active sulfate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 599.0
DTH2_k127_7990556_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 591.0
DTH2_k127_7990556_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000004982 220.0
DTH2_k127_7990556_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000007435 186.0
DTH2_k127_7990556_5 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000956 171.0
DTH2_k127_8012615_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 569.0
DTH2_k127_8012615_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000001984 87.0
DTH2_k127_8012615_2 - - - - 0.000000007942 59.0
DTH2_k127_8012615_3 - - - - 0.0006879 45.0
DTH2_k127_8017433_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 360.0
DTH2_k127_8017433_1 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 302.0
DTH2_k127_8017433_2 ArsC family - - - 0.00000000000000000000000000000000000000000008811 162.0
DTH2_k127_8017433_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000008316 151.0
DTH2_k127_8024046_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.179e-237 745.0
DTH2_k127_8024046_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 5.634e-203 643.0
DTH2_k127_8024046_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 359.0
DTH2_k127_8024046_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 340.0
DTH2_k127_8024046_4 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000005839 231.0
DTH2_k127_8067635_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 419.0
DTH2_k127_8067635_1 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 332.0
DTH2_k127_8067635_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 343.0
DTH2_k127_8067635_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000003737 94.0
DTH2_k127_8082567_0 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 317.0
DTH2_k127_8082567_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000009002 202.0
DTH2_k127_8082567_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000007501 122.0
DTH2_k127_8082567_3 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000402 69.0
DTH2_k127_8082567_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000004777 57.0
DTH2_k127_8093763_0 PFAM Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 478.0
DTH2_k127_8093763_1 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 434.0
DTH2_k127_8093763_2 Surface antigen variable number K07001 - - 0.000000000000000000000000000000000000000000000000000000000000005684 246.0
DTH2_k127_809831_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 569.0
DTH2_k127_809831_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 314.0
DTH2_k127_8137269_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 385.0
DTH2_k127_8137269_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000001076 232.0
DTH2_k127_8137269_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000001941 183.0
DTH2_k127_8137269_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000573 183.0
DTH2_k127_8139005_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 591.0
DTH2_k127_8139005_1 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 537.0
DTH2_k127_8139005_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 492.0
DTH2_k127_8139005_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 391.0
DTH2_k127_8139005_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001513 250.0
DTH2_k127_8185326_0 Elongation factor G C-terminus K06207 - - 1.104e-267 837.0
DTH2_k127_8185326_1 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007351 254.0
DTH2_k127_8244285_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.443e-211 683.0
DTH2_k127_8244285_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 595.0
DTH2_k127_8244285_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 572.0
DTH2_k127_8244285_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 340.0
DTH2_k127_8244285_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 325.0
DTH2_k127_8244285_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003194 270.0
DTH2_k127_8244285_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000005213 107.0
DTH2_k127_8250164_0 FAD dependent oxidoreductase - - - 2.571e-227 717.0
DTH2_k127_8250164_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 514.0
DTH2_k127_8250164_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000001406 149.0
DTH2_k127_8317990_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 1391.0
DTH2_k127_8317990_1 Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 315.0
DTH2_k127_8326974_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000002096 236.0
DTH2_k127_8326974_1 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000000003376 172.0
DTH2_k127_8326974_2 cellulose binding - - - 0.000007687 54.0
DTH2_k127_8343953_0 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001381 282.0
DTH2_k127_8343953_1 DbpA RNA binding domain K05592 - 3.6.4.13 0.000009408 54.0
DTH2_k127_836641_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000004069 200.0
DTH2_k127_836641_1 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.000000000000000000000000000000000001079 154.0
DTH2_k127_836641_2 dCMP deaminase activity K01493 - 3.5.4.12 0.0000000000000000000002702 105.0
DTH2_k127_8400389_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 611.0
DTH2_k127_8400389_1 Type II/IV secretion system protein K02669 - - 0.000000297 59.0
DTH2_k127_8409696_0 Large extracellular alpha-helical protein K06894 - - 3.627e-205 659.0
DTH2_k127_8409696_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 526.0
DTH2_k127_8409696_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001121 249.0
DTH2_k127_8409696_3 - - - - 0.000000000000000000000000000000000000000000001138 178.0
DTH2_k127_8409696_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000203 139.0
DTH2_k127_8409696_5 - - - - 0.000000000000000000000000000000008485 134.0
DTH2_k127_8409696_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000001496 78.0
DTH2_k127_8409696_7 TIGRFAM HAD-superfamily hydrolase subfamily IA, variant - - - 0.0003645 49.0
DTH2_k127_846060_0 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 546.0
DTH2_k127_846060_1 alanine racemase K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000421 214.0
DTH2_k127_846060_2 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000004401 150.0
DTH2_k127_846060_3 PFAM Membrane protein of K08972 - - 0.000000000000000000000000001555 116.0
DTH2_k127_8475503_0 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000000746 142.0
DTH2_k127_8475503_1 Acyl-CoA synthetase (NDP forming) - - - 0.000000000000000000006076 98.0
DTH2_k127_8475503_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000008247 99.0
DTH2_k127_851_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 338.0
DTH2_k127_851_1 SMART glycoside hydrolase family 29 (alpha-L- fucosidase) K01206 - 3.2.1.51 0.00001072 49.0
DTH2_k127_8513038_0 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005464 276.0
DTH2_k127_8513038_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00001309 57.0
DTH2_k127_8525505_0 Amino acid permease K03756,K03759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 431.0
DTH2_k127_8525505_1 phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000003473 248.0
DTH2_k127_8525505_2 - - - - 0.00000000000000000000000000006801 116.0
DTH2_k127_8525505_4 Orn/Lys/Arg decarboxylase, N-terminal domain - - - 0.000000151 52.0
DTH2_k127_8538863_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 419.0
DTH2_k127_8538863_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000004634 231.0
DTH2_k127_8538863_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000002613 172.0
DTH2_k127_8538863_3 receptor K16087 - - 0.00000000000000000000000000002216 132.0
DTH2_k127_8587199_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 338.0
DTH2_k127_8587199_1 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000344 206.0
DTH2_k127_8587199_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000005427 98.0
DTH2_k127_8610495_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 9.592e-214 678.0
DTH2_k127_8610495_1 DinB family - - - 0.0004585 44.0
DTH2_k127_8824683_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 621.0
DTH2_k127_8824683_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 479.0
DTH2_k127_8824683_2 Dihydroxyacetone kinase family K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 370.0
DTH2_k127_8824683_3 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000307 150.0
DTH2_k127_8824683_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000009217 124.0
DTH2_k127_8824683_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000001272 107.0
DTH2_k127_8824683_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000371 104.0
DTH2_k127_8824683_7 - - - - 0.00000000001348 75.0
DTH2_k127_8859198_0 Penicillin amidase K07116 - 3.5.1.97 1.213e-194 624.0
DTH2_k127_8912367_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 6.301e-299 959.0
DTH2_k127_8912367_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 7.896e-249 783.0
DTH2_k127_8912367_2 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 426.0
DTH2_k127_8912367_3 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.00000000000000000000000000000000000000000000000000002933 192.0
DTH2_k127_8912367_4 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000000000000000000000000001618 156.0
DTH2_k127_8912367_5 Bacterial PH domain - - - 0.000000000000000000000000000000607 128.0
DTH2_k127_8912367_6 YGGT family K02221 - - 0.000000000000000000000000006894 117.0
DTH2_k127_8912367_7 Belongs to the UPF0235 family K09131 - - 0.00000000000000000001459 98.0
DTH2_k127_8912367_8 Membrane - - - 0.0000001305 62.0
DTH2_k127_8912367_9 TonB-dependent receptor - - - 0.0000007245 51.0
DTH2_k127_8938389_0 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 345.0
DTH2_k127_8938389_1 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000001076 235.0
DTH2_k127_8938389_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000006425 209.0
DTH2_k127_8953291_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 451.0
DTH2_k127_8953291_1 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 377.0
DTH2_k127_8953291_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 306.0
DTH2_k127_8953291_3 Pfam:UPF0118 - - - 0.000000000000000000000000000000000005654 149.0
DTH2_k127_8998675_0 ABC transporter K06020 - 3.6.3.25 1.211e-232 729.0
DTH2_k127_8998675_1 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000965 226.0
DTH2_k127_9008443_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 507.0
DTH2_k127_9008443_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 346.0
DTH2_k127_9008443_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 321.0
DTH2_k127_9008443_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000571 288.0
DTH2_k127_9008443_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000006166 179.0
DTH2_k127_9036938_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 586.0
DTH2_k127_9036938_1 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 486.0
DTH2_k127_9036938_2 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 352.0
DTH2_k127_9036938_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000008424 243.0
DTH2_k127_9036938_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000002521 230.0
DTH2_k127_9036938_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000196 200.0
DTH2_k127_9036938_6 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000003377 143.0
DTH2_k127_9050207_0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 505.0
DTH2_k127_9050207_1 nucleotidyl transferase K01841,K03430,K07281,K07291,K09809,K22424 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0016780 2.6.1.37,2.7.3.13,2.7.7.74,2.7.8.12,2.7.8.34,5.4.2.9 0.00000000000000000000000000000000000000000000000000000001017 206.0
DTH2_k127_9066687_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 2841.0
DTH2_k127_9066687_1 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 411.0
DTH2_k127_9066687_2 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.000000000000000000114 93.0
DTH2_k127_910330_0 von Willebrand factor (vWF) type A domain - - - 1.512e-201 637.0
DTH2_k127_910330_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 314.0
DTH2_k127_910330_2 alpha-l-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002483 287.0
DTH2_k127_910330_3 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000002032 152.0
DTH2_k127_9115022_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1290.0
DTH2_k127_9115022_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 414.0
DTH2_k127_9115022_2 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001892 282.0
DTH2_k127_9115022_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001825 268.0
DTH2_k127_9115022_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000006305 239.0
DTH2_k127_9115022_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000001178 180.0
DTH2_k127_9115022_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000132 184.0
DTH2_k127_9115022_7 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000001285 159.0
DTH2_k127_9115022_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000002005 63.0
DTH2_k127_912233_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 534.0
DTH2_k127_912233_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 518.0
DTH2_k127_912233_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K11529,K15893 - 1.1.1.26,2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000009629 268.0
DTH2_k127_912233_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000007441 238.0
DTH2_k127_9153072_0 Zinc carboxypeptidase - - - 7.197e-247 784.0
DTH2_k127_9153072_1 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 3.323e-241 766.0
DTH2_k127_9153072_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 458.0
DTH2_k127_9153072_3 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009556 256.0
DTH2_k127_9153072_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000004517 161.0
DTH2_k127_9153072_5 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000005675 144.0
DTH2_k127_9304512_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 1.537e-238 758.0
DTH2_k127_9304512_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 440.0
DTH2_k127_9304512_2 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000002819 277.0
DTH2_k127_9304512_3 Aminotransferase class-V - - - 0.0000000000002778 72.0
DTH2_k127_9304512_4 Regulates arginine biosynthesis genes K03402 - - 0.000000000000382 72.0
DTH2_k127_9307080_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 483.0
DTH2_k127_9307080_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 305.0
DTH2_k127_9307080_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000008038 151.0
DTH2_k127_9307080_3 - - - - 0.000000000000003721 81.0
DTH2_k127_9316338_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 533.0
DTH2_k127_9316338_1 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 301.0
DTH2_k127_9316338_2 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000003372 194.0
DTH2_k127_9331029_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 402.0
DTH2_k127_9331029_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 289.0
DTH2_k127_9331029_2 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000005642 219.0
DTH2_k127_9331029_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000009183 211.0
DTH2_k127_9331029_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000126 157.0
DTH2_k127_9331029_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000007858 108.0
DTH2_k127_9376438_0 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 412.0
DTH2_k127_9376438_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 296.0
DTH2_k127_9376438_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000007741 200.0
DTH2_k127_9376438_3 - - - - 0.000000000000000000000000000000000000000000000000006983 186.0
DTH2_k127_9376438_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000001873 183.0
DTH2_k127_9376438_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000004869 122.0
DTH2_k127_9387966_0 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 388.0
DTH2_k127_9387966_1 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000002157 271.0
DTH2_k127_9387966_2 - - - - 0.0000000000000000000000000001849 132.0
DTH2_k127_9387966_3 Protein tyrosine kinase - - - 0.00000004626 58.0
DTH2_k127_9387966_4 general secretion pathway protein - - - 0.0004509 46.0
DTH2_k127_9434101_0 protein kinase activity - - - 1.607e-225 729.0
DTH2_k127_9434101_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 531.0
DTH2_k127_9434101_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 293.0
DTH2_k127_9434101_3 protein kinase activity - - - 0.00000000001744 64.0
DTH2_k127_9441400_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000001562 222.0
DTH2_k127_9455597_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 9.894e-281 881.0
DTH2_k127_9455597_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 370.0
DTH2_k127_9455597_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 325.0
DTH2_k127_9455597_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000001531 180.0
DTH2_k127_9455597_4 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.0000000000000001772 84.0
DTH2_k127_9485972_0 oligopeptidase that cleaves peptide bonds following arginine and lysine residues K01354 - 3.4.21.83 9.668e-257 809.0
DTH2_k127_9485972_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 531.0
DTH2_k127_9485972_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000001988 175.0
DTH2_k127_9485972_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000002308 146.0
DTH2_k127_9485972_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000002723 100.0
DTH2_k127_9485972_5 membrane-associated protein - - - 0.0000000000003238 79.0
DTH2_k127_954446_0 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 506.0
DTH2_k127_954446_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 459.0
DTH2_k127_954446_2 Type II secretion system (T2SS), protein M subtype b - - - 0.00000000001505 69.0
DTH2_k127_954446_3 - - - - 0.000629 51.0
DTH2_k127_9559175_0 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 293.0
DTH2_k127_9559175_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000003245 57.0
DTH2_k127_9570458_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002626 241.0
DTH2_k127_9570458_1 Curli production assembly transport component CsgG - - - 0.000000000000001032 88.0
DTH2_k127_9591818_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 558.0
DTH2_k127_9591818_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000001896 143.0
DTH2_k127_9607437_0 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 342.0
DTH2_k127_9607437_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000006929 231.0
DTH2_k127_9607437_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000001534 176.0
DTH2_k127_9607437_3 DinB family - - - 0.000000000000000000000000000000000002052 143.0
DTH2_k127_9607437_4 TAP-like protein - - - 0.00000000000000000001332 98.0
DTH2_k127_9616166_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 346.0
DTH2_k127_9616166_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 322.0
DTH2_k127_9616166_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
DTH2_k127_9616166_3 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000001537 229.0
DTH2_k127_9689112_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 440.0
DTH2_k127_9689112_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 366.0
DTH2_k127_9689112_2 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 356.0
DTH2_k127_9689112_3 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 362.0
DTH2_k127_9689112_4 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 287.0
DTH2_k127_9689112_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000001333 205.0
DTH2_k127_9689112_6 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000191 130.0
DTH2_k127_9708250_0 TonB-dependent receptor - - - 8.896e-240 764.0
DTH2_k127_9708250_1 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 362.0
DTH2_k127_9738181_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 2.324e-210 664.0
DTH2_k127_9738181_1 Phage integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 373.0
DTH2_k127_9738181_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000006986 226.0
DTH2_k127_9738181_3 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000008064 226.0
DTH2_k127_9738181_4 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000003402 202.0
DTH2_k127_9738181_5 Fic/DOC family K07341 - - 0.00000000000000000000000000000000001966 138.0
DTH2_k127_9738181_6 Zincin-like metallopeptidase - - - 0.00000000000001933 86.0
DTH2_k127_9757081_0 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001905 263.0
DTH2_k127_9757081_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002559 262.0
DTH2_k127_9757081_2 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
DTH2_k127_9817294_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001893 274.0
DTH2_k127_9817294_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004118 248.0
DTH2_k127_9817294_2 HD domain - - - 0.000000000000000000000000001264 120.0
DTH2_k127_9817294_3 Diacylglycerol kinase - - - 0.00000000000000000000000002578 121.0
DTH2_k127_9817294_4 PFAM peptidase S58 DmpA - - - 0.0000000000000002081 85.0
DTH2_k127_9817797_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 396.0
DTH2_k127_9817797_1 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000004927 212.0
DTH2_k127_9817797_2 lipopolysaccharide-transporting ATPase activity K06861 - - 0.00000000000000000000000000000006129 134.0
DTH2_k127_986598_0 B12 binding domain - - - 1.864e-234 737.0
DTH2_k127_986598_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 364.0
DTH2_k127_986598_2 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000656 278.0
DTH2_k127_986598_3 Fibronectin type 3 domain - - - 0.0000000000001672 83.0