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Overview

ID MAG00775
Name DTH2_bin.40
Sample SMP0023
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order Methanomassiliicoccales
Family UBA472
Genus JAJRAN01
Species
Assembly information
Completeness (%) 83.87
Contamination (%) 2.6
GC content (%) 58.0
N50 (bp) 5,729
Genome size (bp) 1,580,580

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1623

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10035797_0 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000004415 235.0
DTH2_k127_10035797_1 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000001458 169.0
DTH2_k127_10035797_2 Transcriptional regulator K07108 - - 0.000000000000000000000000000000003694 132.0
DTH2_k127_10035797_3 Adenosine specific kinase K09129 - - 0.000000000000000008475 83.0
DTH2_k127_10050577_0 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001018 274.0
DTH2_k127_10050577_1 Transcriptional regulator - - - 0.0000000000006615 76.0
DTH2_k127_10060462_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 317.0
DTH2_k127_10060462_1 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000005284 149.0
DTH2_k127_10060462_10 Glyoxalase-like domain - - - 0.0000000002361 63.0
DTH2_k127_10060462_2 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.0000000000000000000000000000002005 128.0
DTH2_k127_10060462_3 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000001487 109.0
DTH2_k127_10060462_4 Protein of unknown function (DUF835) - - - 0.0000000000000000008609 99.0
DTH2_k127_10060462_5 - K00960 - 2.7.7.6 0.00000000000000000362 84.0
DTH2_k127_10060462_6 TIGRFAM C_GCAxxG_C_C family protein - - - 0.000000000000000009947 88.0
DTH2_k127_10060462_7 Rubredoxin - - - 0.00000000000000007632 89.0
DTH2_k127_10060462_8 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000004702 86.0
DTH2_k127_10060462_9 trans-aconitate 2-methyltransferase activity K02169,K15256 - 2.1.1.197 0.000000000005112 74.0
DTH2_k127_1067587_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 542.0
DTH2_k127_1067587_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 406.0
DTH2_k127_1067587_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 372.0
DTH2_k127_1067587_3 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145,K05829 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 357.0
DTH2_k127_1093016_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000001005 187.0
DTH2_k127_1093016_1 - - - - 0.00000001012 63.0
DTH2_k127_1108699_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 543.0
DTH2_k127_1108699_1 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.00000000000001068 78.0
DTH2_k127_1108699_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000003266 68.0
DTH2_k127_1108699_3 Small-conductance mechanosensitive channel - - - 0.00004924 55.0
DTH2_k127_1121156_0 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001452 280.0
DTH2_k127_1121156_1 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000002913 237.0
DTH2_k127_1121156_2 Helix-turn-helix domain - - - 0.00000001143 59.0
DTH2_k127_1139593_0 HELICc2 K03722,K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 307.0
DTH2_k127_1139593_1 - - - - 0.000000000000000000000000000000002829 130.0
DTH2_k127_1150891_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 7.867e-283 893.0
DTH2_k127_1150891_1 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000002764 175.0
DTH2_k127_1150891_2 TIGRFAM Outer membrane protein K13735,K20276 - - 0.00000000002186 78.0
DTH2_k127_1188800_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.04e-300 939.0
DTH2_k127_1188800_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 580.0
DTH2_k127_1188800_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 357.0
DTH2_k127_1188800_3 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 297.0
DTH2_k127_1188800_4 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
DTH2_k127_1188800_5 Fcf1 K07158 - - 0.00000000000000000000000000000008316 128.0
DTH2_k127_1243950_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 451.0
DTH2_k127_1284065_0 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 409.0
DTH2_k127_1284065_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 408.0
DTH2_k127_1284065_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341,K22167 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000121 291.0
DTH2_k127_1284065_3 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
DTH2_k127_1284065_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000000000007489 158.0
DTH2_k127_1320258_0 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 539.0
DTH2_k127_1320258_1 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 280.0
DTH2_k127_1320258_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000002077 227.0
DTH2_k127_1320258_3 Acetyltransferase (GNAT) domain - - - 0.000000000000008482 87.0
DTH2_k127_1320258_4 PFAM PP-loop domain protein K06864 - - 0.000000000003615 70.0
DTH2_k127_133549_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 391.0
DTH2_k127_133549_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000142 171.0
DTH2_k127_133549_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000003741 137.0
DTH2_k127_133549_3 Glyoxalase-like domain - - - 0.000000000000000000001156 96.0
DTH2_k127_1339474_0 Fibronectin type III domain K12567 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 448.0
DTH2_k127_1339474_1 Protein of unknown function (DUF1698) - - - 0.0000000000000004847 87.0
DTH2_k127_1339474_2 Protein of unknown function (DUF1616) - - - 0.000000000000002536 87.0
DTH2_k127_1365920_0 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 375.0
DTH2_k127_1365920_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 347.0
DTH2_k127_1365920_2 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 313.0
DTH2_k127_1365920_3 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001326 286.0
DTH2_k127_1365920_4 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003321 250.0
DTH2_k127_1365920_5 PFAM PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000002072 175.0
DTH2_k127_1365920_6 Protein of unknown function (DUF2797) - - - 0.000000001479 68.0
DTH2_k127_1365920_7 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.00000001646 58.0
DTH2_k127_1395949_0 CobW/HypB/UreG, nucleotide-binding domain - - - 1.532e-200 633.0
DTH2_k127_1395949_1 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000002387 237.0
DTH2_k127_1395949_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000002034 85.0
DTH2_k127_1395949_3 - - - - 0.00000000000001378 80.0
DTH2_k127_1431973_0 Methionine synthase B12-binding module cap domain protein K16179 - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
DTH2_k127_1431973_1 Amidohydrolase K07045 - - 0.000000000000000000000000005428 122.0
DTH2_k127_1431973_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000005611 107.0
DTH2_k127_1431973_3 Uroporphyrinogen decarboxylase K01599 - 4.1.1.37 0.00000839 48.0
DTH2_k127_1431973_4 membrane - - - 0.00001934 53.0
DTH2_k127_1459968_0 PFAM Hydantoinase oxoprolinase - - - 0.0000000000000000000000000000000000000000001005 166.0
DTH2_k127_1494667_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 336.0
DTH2_k127_1494667_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009853 284.0
DTH2_k127_1585142_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000003361 147.0
DTH2_k127_1585142_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000009624 105.0
DTH2_k127_1585142_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000003876 63.0
DTH2_k127_1585142_3 - - - - 0.0000008168 61.0
DTH2_k127_1589013_0 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000341 224.0
DTH2_k127_1624380_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 362.0
DTH2_k127_1624380_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001977 274.0
DTH2_k127_1624380_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000577 82.0
DTH2_k127_1624380_3 - - - - 0.00002742 54.0
DTH2_k127_1624380_4 - - - - 0.00003617 53.0
DTH2_k127_16411_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 341.0
DTH2_k127_16411_1 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002064 251.0
DTH2_k127_1658643_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 461.0
DTH2_k127_1658643_1 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 332.0
DTH2_k127_1658643_2 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 293.0
DTH2_k127_1658643_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000006607 249.0
DTH2_k127_1658643_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000003616 228.0
DTH2_k127_1658643_5 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000004414 191.0
DTH2_k127_1658643_6 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000002499 165.0
DTH2_k127_1658643_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000187 131.0
DTH2_k127_1658643_8 - - - - 0.00004768 52.0
DTH2_k127_1658643_9 PFAM CoA-binding domain protein K01905 - 6.2.1.13 0.0001411 45.0
DTH2_k127_1707792_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1798.0
DTH2_k127_1707792_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 5.63e-322 996.0
DTH2_k127_1707792_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000002477 81.0
DTH2_k127_1712289_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 325.0
DTH2_k127_1712289_1 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000155 260.0
DTH2_k127_1712289_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000006257 161.0
DTH2_k127_1712289_3 - - - - 0.00000000000000000000000000000000000001958 152.0
DTH2_k127_1757823_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 450.0
DTH2_k127_1757823_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 314.0
DTH2_k127_1757823_2 virion core protein (lumpy skin disease virus) - - - 0.000488 51.0
DTH2_k127_1830212_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 574.0
DTH2_k127_1830212_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 530.0
DTH2_k127_1830212_10 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000004089 198.0
DTH2_k127_1830212_11 PFAM AmiS UreI transporter K03191,K22112 - - 0.00000000000000000000002478 106.0
DTH2_k127_1830212_12 Methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.00000000000000000000007116 111.0
DTH2_k127_1830212_13 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000002024 100.0
DTH2_k127_1830212_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 388.0
DTH2_k127_1830212_3 Isocitrate/isopropylmalate dehydrogenase K00030,K00052,K07246,K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.41,1.1.1.83,1.1.1.85,1.1.1.87,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 372.0
DTH2_k127_1830212_4 Coenzyme A transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 354.0
DTH2_k127_1830212_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 360.0
DTH2_k127_1830212_6 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 345.0
DTH2_k127_1830212_7 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004437 279.0
DTH2_k127_1830212_8 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000002359 224.0
DTH2_k127_1830212_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000001182 216.0
DTH2_k127_1837014_0 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000004935 205.0
DTH2_k127_1837014_1 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000009743 111.0
DTH2_k127_1837014_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000006506 93.0
DTH2_k127_186961_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 487.0
DTH2_k127_186961_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 369.0
DTH2_k127_186961_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000000000000003692 232.0
DTH2_k127_186961_3 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000001439 145.0
DTH2_k127_186961_4 COG1042 Acyl-CoA synthetase (NDP forming) K01905,K22224 - 6.2.1.13 0.00000000000000000000003137 101.0
DTH2_k127_1894102_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 415.0
DTH2_k127_1894102_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000004378 258.0
DTH2_k127_1894102_2 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00002164 49.0
DTH2_k127_1928386_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 625.0
DTH2_k127_1928386_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 535.0
DTH2_k127_1928386_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000313 225.0
DTH2_k127_1928386_3 Domain of unknown function (DUF4443) - - - 0.000000000000000000000000000000000000000000000009304 177.0
DTH2_k127_1928386_4 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000009444 81.0
DTH2_k127_1928386_5 - - - - 0.00000000000001494 79.0
DTH2_k127_1939343_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 455.0
DTH2_k127_1939343_1 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001801 287.0
DTH2_k127_1939343_2 - - - - 0.0000000000000000002709 92.0
DTH2_k127_1957668_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 430.0
DTH2_k127_1957668_1 NMD3 family K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000002465 244.0
DTH2_k127_1957668_2 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000002701 114.0
DTH2_k127_1957668_3 molybdopterin binding domain - - - 0.000000000000000000001431 103.0
DTH2_k127_2037370_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 371.0
DTH2_k127_2037370_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 314.0
DTH2_k127_2037370_2 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008314 286.0
DTH2_k127_2037370_3 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000001873 179.0
DTH2_k127_2037370_4 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000004571 168.0
DTH2_k127_2037370_5 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000009135 143.0
DTH2_k127_2037370_6 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000004926 104.0
DTH2_k127_2037370_7 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000001171 109.0
DTH2_k127_2055553_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.958e-222 702.0
DTH2_k127_2055553_1 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000001611 128.0
DTH2_k127_2055553_2 xylanase chitin deacetylase K22278 - 3.5.1.104 0.00000000000000000007387 94.0
DTH2_k127_2060410_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 431.0
DTH2_k127_2060410_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 409.0
DTH2_k127_2060410_2 PFAM tRNA methyltransferase complex GCD14 subunit K07442 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0031515,GO:0032991,GO:0034708,GO:0043527,GO:0044424,GO:0044444,GO:0044464,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000004237 248.0
DTH2_k127_2060410_3 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000002347 169.0
DTH2_k127_2060410_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000001385 103.0
DTH2_k127_2081403_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 593.0
DTH2_k127_2081403_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003847 282.0
DTH2_k127_2081403_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000000218 220.0
DTH2_k127_2081403_3 Protein of unknown function TPD sequence-motif - - - 0.0002177 44.0
DTH2_k127_2090593_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 367.0
DTH2_k127_2090593_1 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000005323 213.0
DTH2_k127_2090593_2 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000006811 156.0
DTH2_k127_2106212_0 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000001896 138.0
DTH2_k127_2106212_1 transcriptional regulators - - - 0.000000000000002667 82.0
DTH2_k127_2106212_2 Transcriptional regulators - - - 0.000006514 53.0
DTH2_k127_2145554_0 Putative diphthamide synthesis protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 302.0
DTH2_k127_2145554_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 295.0
DTH2_k127_2145554_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000001823 245.0
DTH2_k127_2145554_3 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001285 213.0
DTH2_k127_2145554_4 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000001563 218.0
DTH2_k127_2145554_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000003435 163.0
DTH2_k127_2145554_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000004828 143.0
DTH2_k127_2183904_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 3.398e-220 702.0
DTH2_k127_2183904_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 465.0
DTH2_k127_2183904_10 homolog of PrgY (pheromone shutdown protein) - - - 0.0000000000000000000000000000000000008557 149.0
DTH2_k127_2183904_11 PFAM Rhomboid family protein K07059 - - 0.00000000000000000000001485 111.0
DTH2_k127_2183904_12 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000004059 85.0
DTH2_k127_2183904_13 ABC-2 type transporter - - - 0.0000004346 54.0
DTH2_k127_2183904_14 Archaeal Type IV pilin, N-terminal - - - 0.00002514 59.0
DTH2_k127_2183904_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 353.0
DTH2_k127_2183904_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 323.0
DTH2_k127_2183904_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 299.0
DTH2_k127_2183904_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000004151 233.0
DTH2_k127_2183904_6 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000003058 210.0
DTH2_k127_2183904_7 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000002179 170.0
DTH2_k127_2183904_8 Methyltransferase domain K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000003479 164.0
DTH2_k127_2183904_9 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000001287 154.0
DTH2_k127_2214109_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 363.0
DTH2_k127_2214109_1 RIO1 family K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001108 285.0
DTH2_k127_2214109_2 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000000000002805 203.0
DTH2_k127_2214109_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001564 117.0
DTH2_k127_2214109_4 RNA polymerase K03051 - 2.7.7.6 0.0000000000005561 73.0
DTH2_k127_2225232_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 307.0
DTH2_k127_2225232_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000002227 237.0
DTH2_k127_2225232_2 DNA polymerase alpha chain like domain K02347 - - 0.00000000004043 68.0
DTH2_k127_2246561_0 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005981 241.0
DTH2_k127_2246561_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000003721 236.0
DTH2_k127_2246561_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000385 199.0
DTH2_k127_2246561_3 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000004285 102.0
DTH2_k127_2246561_4 - - - - 0.0009923 43.0
DTH2_k127_2293270_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 2.159e-197 629.0
DTH2_k127_2293270_1 GrpB protein - - - 0.00000000000000001301 85.0
DTH2_k127_2293270_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000001195 60.0
DTH2_k127_2376067_0 Methyltransferase K08093,K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 533.0
DTH2_k127_2376067_1 Rad51 - - - 0.000000000000000000000000000000000000000000000000000002094 200.0
DTH2_k127_2376067_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000002005 154.0
DTH2_k127_2376067_3 DNA polymerase alpha chain like domain K02347 - - 0.0000000000000000000000000006285 125.0
DTH2_k127_2376067_4 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000001685 104.0
DTH2_k127_2394467_0 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 591.0
DTH2_k127_2394467_1 Glutamate synthase (NADPH) GltB1 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 337.0
DTH2_k127_2394467_2 L-glutamate biosynthetic process - - - 0.000000000001005 72.0
DTH2_k127_2410653_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 283.0
DTH2_k127_2410653_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009166 273.0
DTH2_k127_2428882_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 1.424e-215 685.0
DTH2_k127_2428882_1 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 308.0
DTH2_k127_2428882_2 TIGRFAM small GTP-binding protein K06944 - - 0.0000007482 53.0
DTH2_k127_2428882_3 SPFH domain-Band 7 family - - - 0.00003528 55.0
DTH2_k127_2434633_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001056 260.0
DTH2_k127_2434633_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003164 259.0
DTH2_k127_2434633_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000004679 226.0
DTH2_k127_2477585_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 504.0
DTH2_k127_2477585_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 456.0
DTH2_k127_2477585_10 NIL - - - 0.0000000000000000000000000000006781 126.0
DTH2_k127_2477585_11 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000006888 117.0
DTH2_k127_2477585_12 Helix-turn-helix domain - - - 0.000000000000000001569 91.0
DTH2_k127_2477585_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 395.0
DTH2_k127_2477585_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 388.0
DTH2_k127_2477585_4 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000005211 248.0
DTH2_k127_2477585_5 prephenate dehydrogenase K04517,K14170,K14187 - 1.3.1.12,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000253 251.0
DTH2_k127_2477585_6 shikimate kinase activity K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000004085 235.0
DTH2_k127_2477585_7 Belongs to the UPF0280 family K09740 - - 0.000000000000000000000000000000000000000000000000000000000725 211.0
DTH2_k127_2477585_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000009156 195.0
DTH2_k127_2477585_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000176 151.0
DTH2_k127_2529026_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 417.0
DTH2_k127_2529026_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 349.0
DTH2_k127_2542790_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 548.0
DTH2_k127_2542790_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 314.0
DTH2_k127_2542790_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 284.0
DTH2_k127_2542790_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001478 217.0
DTH2_k127_2542790_4 PFAM GHMP kinase K06982 - 2.7.1.169 0.0000000000000000000000000000000000000000001104 169.0
DTH2_k127_2542790_5 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000000000000001564 146.0
DTH2_k127_2542790_6 Major intrinsic protein - - - 0.00000000000000000000000000000000000001588 153.0
DTH2_k127_2554132_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000003873 210.0
DTH2_k127_2554132_1 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000001413 188.0
DTH2_k127_2554132_2 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0004167 46.0
DTH2_k127_2608662_0 Coenzyme F390 synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 479.0
DTH2_k127_2608662_1 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 383.0
DTH2_k127_2608662_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 335.0
DTH2_k127_2615563_0 - - - - 0.0000000000000000000000000000000000000000000000000000000003506 213.0
DTH2_k127_2615563_1 Carboxypeptidase regulatory-like domain - - - 0.00000005701 63.0
DTH2_k127_2617319_0 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 465.0
DTH2_k127_2617319_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 425.0
DTH2_k127_2617319_2 Radical SAM domain protein - - - 0.0000000000000000000000000000000000001799 150.0
DTH2_k127_2617319_3 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000007745 126.0
DTH2_k127_2617319_4 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000003598 110.0
DTH2_k127_2617319_5 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000002113 98.0
DTH2_k127_2617319_6 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000001116 53.0
DTH2_k127_2625138_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000329 231.0
DTH2_k127_2625138_2 Winged helix-turn-helix - - - 0.00000000000000000000000000006958 118.0
DTH2_k127_2625138_3 - - - - 0.000000000000000000002524 102.0
DTH2_k127_2625138_4 FMN binding K03809 - 1.6.5.2 0.00000001875 61.0
DTH2_k127_2628523_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 501.0
DTH2_k127_2628523_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000003587 226.0
DTH2_k127_2628523_2 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000000006275 176.0
DTH2_k127_2628523_3 Thioredoxin K03671 - - 0.0000000000000000000000004215 110.0
DTH2_k127_2628523_4 - - - - 0.0000002974 61.0
DTH2_k127_2642801_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000006176 184.0
DTH2_k127_2642801_1 Glycosyl transferases group 1 K19002 - 2.4.1.337 0.000004154 56.0
DTH2_k127_2681487_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 584.0
DTH2_k127_2681487_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 480.0
DTH2_k127_2681487_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000002223 229.0
DTH2_k127_2681487_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000009651 221.0
DTH2_k127_2681487_4 RNA secondary structure unwinding K03724 - - 0.0000000000000000000000000000000000000001584 166.0
DTH2_k127_2693549_0 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 584.0
DTH2_k127_2693549_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 423.0
DTH2_k127_2693549_2 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000001209 226.0
DTH2_k127_2693549_3 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000001461 182.0
DTH2_k127_2693549_4 - - - - 0.0000000000000000000000002977 107.0
DTH2_k127_2693549_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.000000000000134 72.0
DTH2_k127_2732972_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 526.0
DTH2_k127_2732972_1 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 514.0
DTH2_k127_2732972_2 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 342.0
DTH2_k127_2732972_3 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000006759 159.0
DTH2_k127_2732972_4 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000005313 122.0
DTH2_k127_2732972_5 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000002758 101.0
DTH2_k127_2732972_6 cheY-homologous receiver domain - - - 0.00000000000001984 83.0
DTH2_k127_2752656_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.886e-203 649.0
DTH2_k127_2752656_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 471.0
DTH2_k127_278514_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 340.0
DTH2_k127_278514_1 toxin-antitoxin pair type II binding - - - 0.000000000000000000000008842 104.0
DTH2_k127_278514_2 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.000000002038 59.0
DTH2_k127_2837128_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 355.0
DTH2_k127_2837128_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 346.0
DTH2_k127_2837128_2 KEOPS complex Cgi121-like subunit K09119 - - 0.00001303 50.0
DTH2_k127_2846734_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000002278 148.0
DTH2_k127_2846734_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000003408 91.0
DTH2_k127_2872192_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1200.0
DTH2_k127_2872192_1 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 518.0
DTH2_k127_2872192_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 399.0
DTH2_k127_2872192_3 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 403.0
DTH2_k127_2872192_4 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 377.0
DTH2_k127_2872192_5 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003124 257.0
DTH2_k127_2872192_6 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000004249 125.0
DTH2_k127_2872192_7 - - - - 0.000001349 57.0
DTH2_k127_2916963_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 471.0
DTH2_k127_2916963_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 443.0
DTH2_k127_2916963_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 267.0
DTH2_k127_2916963_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000001094 239.0
DTH2_k127_2916963_4 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000002794 169.0
DTH2_k127_2916963_5 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0000001844 59.0
DTH2_k127_2916963_6 - - - - 0.00001745 50.0
DTH2_k127_2954857_0 C-terminal region of MMR_HSR1 domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 420.0
DTH2_k127_2954857_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 392.0
DTH2_k127_2954857_2 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000003474 190.0
DTH2_k127_2954857_3 Uroporphyrinogen decarboxylase K14080 - 2.1.1.246 0.00000000000000000000001141 113.0
DTH2_k127_2972100_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 421.0
DTH2_k127_2972100_1 PFAM isocitrate isopropylmalate dehydrogenase K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 306.0
DTH2_k127_2972100_2 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 301.0
DTH2_k127_2972100_3 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.00000000000000000000000000000000000003545 153.0
DTH2_k127_2972100_4 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000001825 136.0
DTH2_k127_2972100_5 MgtC family - - - 0.00000000000000000001937 99.0
DTH2_k127_2972100_6 Histidine kinase - - - 0.0004874 46.0
DTH2_k127_2972536_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 410.0
DTH2_k127_2972536_1 - - - - 0.00000003122 66.0
DTH2_k127_2976180_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 471.0
DTH2_k127_2976180_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 440.0
DTH2_k127_2976180_2 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 390.0
DTH2_k127_2976180_3 Amino acid kinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 385.0
DTH2_k127_2976180_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 297.0
DTH2_k127_2976180_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000006576 63.0
DTH2_k127_2989260_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005315 265.0
DTH2_k127_2989260_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000006022 188.0
DTH2_k127_2993990_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 538.0
DTH2_k127_2993990_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000157 161.0
DTH2_k127_2993990_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000002097 120.0
DTH2_k127_2993990_3 FR47-like protein - - - 0.00000000000000005802 83.0
DTH2_k127_3007111_0 Lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 436.0
DTH2_k127_3007111_1 Uncharacterised ACR, YkgG family COG1556 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 305.0
DTH2_k127_3037482_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 393.0
DTH2_k127_3037482_1 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000007498 184.0
DTH2_k127_3037482_2 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000001444 150.0
DTH2_k127_3037482_3 - K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000666 87.0
DTH2_k127_3039310_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000921 193.0
DTH2_k127_3039310_1 fumarate reductase K18210 - 1.3.4.1 0.0000000000000000000000000000000000000000000009461 178.0
DTH2_k127_3039310_2 TIGRFAM Glycerol-3-phosphate dehydrogenase, anaerobic A subunit K00111 - 1.1.5.3 0.000000000000000003776 89.0
DTH2_k127_3039310_3 TIGRFAM Glycerol-3-phosphate dehydrogenase, anaerobic B subunit K00112 - 1.1.5.3 0.00000000000002518 85.0
DTH2_k127_3040583_0 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 533.0
DTH2_k127_3040583_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000002048 241.0
DTH2_k127_3040583_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000006059 232.0
DTH2_k127_3040583_3 TrkA-C domain protein - - - 0.00000000000000000000000000000000000000000000000000000002668 204.0
DTH2_k127_3040583_4 PhoU domain - - - 0.0000000000000000000000000000000000000000000000011 181.0
DTH2_k127_3040583_5 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000001923 169.0
DTH2_k127_3040583_6 PFAM Peptidase - - - 0.00000000000000000000000000000000003265 142.0
DTH2_k127_3040583_7 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000001972 126.0
DTH2_k127_3040583_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000003048 124.0
DTH2_k127_3097201_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000004555 273.0
DTH2_k127_3097201_1 Protein of unknown function (DUF531) K09725 - - 0.0000000000000000000000000000000000000000000000000000000000616 210.0
DTH2_k127_3097201_2 SMART Elongator protein 3 MiaB NifB K13601 - 2.1.1.332 0.0000003951 59.0
DTH2_k127_3097201_3 - - - - 0.0000009651 52.0
DTH2_k127_3106212_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 358.0
DTH2_k127_3106212_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 286.0
DTH2_k127_3106212_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000005832 196.0
DTH2_k127_3106212_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000003537 122.0
DTH2_k127_3106212_4 Transcription elongation factor Spt5 K02601 - - 0.00000000000000001172 82.0
DTH2_k127_316215_0 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 357.0
DTH2_k127_316215_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004567 274.0
DTH2_k127_316215_2 DNA polymerase alpha chain like domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002836 246.0
DTH2_k127_316215_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000008956 236.0
DTH2_k127_316215_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000188 166.0
DTH2_k127_316215_5 aminotransferase - - - 0.000000000000000000000000000000002997 139.0
DTH2_k127_3183475_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 498.0
DTH2_k127_3183475_1 PFAM GvpD gas vesicle - - - 0.00000000000000000005409 97.0
DTH2_k127_3239459_0 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001464 257.0
DTH2_k127_3239459_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000001119 168.0
DTH2_k127_3239459_2 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.000000000000000000004837 100.0
DTH2_k127_326987_0 helicase superfamily c-terminal domain K05592,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000593 192.0
DTH2_k127_326987_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000001933 181.0
DTH2_k127_326987_2 Protein involved in cellulose biosynthesis - - - 0.0000000000000000002082 101.0
DTH2_k127_326987_3 Protein involved in cellulose biosynthesis - - - 0.000000000008271 77.0
DTH2_k127_3291360_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 452.0
DTH2_k127_3327888_0 CTP synthase N-terminus K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 508.0
DTH2_k127_3327888_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000000007715 241.0
DTH2_k127_3327888_2 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000000006487 204.0
DTH2_k127_3327888_3 4Fe-4S ferredoxin iron-sulfur binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000001895 181.0
DTH2_k127_3327888_4 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000000000000000000000000000000000000001869 178.0
DTH2_k127_3327888_5 - - - - 0.0000000008459 68.0
DTH2_k127_3330175_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 473.0
DTH2_k127_3330175_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 321.0
DTH2_k127_3330175_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 286.0
DTH2_k127_3330175_3 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000001863 250.0
DTH2_k127_3330175_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000207 198.0
DTH2_k127_3330175_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000001563 142.0
DTH2_k127_3330175_6 PFAM CBS domain - - - 0.000000000000000000004278 98.0
DTH2_k127_3330175_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000001682 86.0
DTH2_k127_338207_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 355.0
DTH2_k127_338207_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 329.0
DTH2_k127_338207_2 regulatory protein, arsR - - - 0.0000000004681 68.0
DTH2_k127_342828_0 DEAD/H associated K03724 - - 6.085e-276 867.0
DTH2_k127_342828_1 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 465.0
DTH2_k127_342828_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05559,K14086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 379.0
DTH2_k127_342828_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000003842 165.0
DTH2_k127_342828_4 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000000003194 74.0
DTH2_k127_342828_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000288 61.0
DTH2_k127_342828_6 glyoxalase III activity - - - 0.000001468 55.0
DTH2_k127_3431620_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 457.0
DTH2_k127_3431620_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 276.0
DTH2_k127_3431620_2 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000009582 205.0
DTH2_k127_3431620_3 - - - - 0.000000000000000000000000000000000000000000000000000000136 200.0
DTH2_k127_3431620_4 PFAM DoxX family protein K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000003917 186.0
DTH2_k127_3433554_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000001695 216.0
DTH2_k127_3433554_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001423 217.0
DTH2_k127_3433554_2 KaiC K07331 - - 0.0000000000000000000000000000000000000000000000006162 183.0
DTH2_k127_3433554_3 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000796 81.0
DTH2_k127_3433554_4 TfoX N-terminal domain - - - 0.0000000000001105 75.0
DTH2_k127_3433554_5 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000007052 70.0
DTH2_k127_3433554_6 - - - - 0.00000001204 62.0
DTH2_k127_3433554_7 PFAM Uncharacterised conserved protein UCP004962 - - - 0.000002014 51.0
DTH2_k127_3433554_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00002698 52.0
DTH2_k127_3443863_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000909 127.0
DTH2_k127_3443863_1 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000005303 121.0
DTH2_k127_3485948_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 375.0
DTH2_k127_3485948_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000969 220.0
DTH2_k127_3485948_2 Histidine kinase K02486 - 2.7.13.3 0.000000000000000000000000000000000002503 150.0
DTH2_k127_3491151_0 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000001897 241.0
DTH2_k127_3491151_1 DNA binding protein K06930 - - 0.0000000000000000000000006548 115.0
DTH2_k127_3498294_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 325.0
DTH2_k127_3498294_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009322 282.0
DTH2_k127_3498294_2 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
DTH2_k127_3498294_3 PFAM Major Facilitator Superfamily K19576 - - 0.00000000000000000000000000000000000000000000000000000000000000002046 237.0
DTH2_k127_3498294_4 TRAM domain - - - 0.00000000000001168 76.0
DTH2_k127_3498294_5 - - - - 0.0000002997 55.0
DTH2_k127_3511312_0 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 396.0
DTH2_k127_3511312_1 - - - - 0.000000000000000004726 84.0
DTH2_k127_3511312_2 Belongs to the UPF0216 family K09737 - - 0.000000000000000009336 88.0
DTH2_k127_3517204_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 320.0
DTH2_k127_3517204_1 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000002843 229.0
DTH2_k127_3517204_2 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000001611 166.0
DTH2_k127_3517204_3 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000004525 163.0
DTH2_k127_3517204_4 Periplasmic Protein - - - 0.000000000000000000000000000001773 136.0
DTH2_k127_3517204_5 Kelch motif - - - 0.0003749 53.0
DTH2_k127_3525446_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.399e-305 947.0
DTH2_k127_3525446_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000001166 212.0
DTH2_k127_3525446_2 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000006132 111.0
DTH2_k127_3552430_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 347.0
DTH2_k127_3552430_1 structural constituent of ribosome K02912 - - 0.000000000000000000000000000000000000000000000000000009683 197.0
DTH2_k127_3552430_2 binds to the 23S rRNA K02885 - - 0.000000000000000000000000000000000000000000000000002234 185.0
DTH2_k127_3552430_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000003106 187.0
DTH2_k127_3552430_4 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006968 115.0
DTH2_k127_3564673_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 266.0
DTH2_k127_3564673_1 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
DTH2_k127_3567326_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1455.0
DTH2_k127_3567326_1 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 330.0
DTH2_k127_3567326_2 AsnC family - - - 0.00000004955 64.0
DTH2_k127_3572304_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.841e-205 659.0
DTH2_k127_3572304_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 466.0
DTH2_k127_3572304_2 Radical SAM domain protein K02585 - - 0.000000000000000000000000000000000000000000000000000000003778 209.0
DTH2_k127_3593885_0 to cation transporters K07244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
DTH2_k127_3593885_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000002078 230.0
DTH2_k127_3628736_0 Oxidoreductase NAD-binding domain K17995 - 1.12.98.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 340.0
DTH2_k127_3628736_1 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 340.0
DTH2_k127_3628736_2 - - - - 0.0000000000000000000001715 100.0
DTH2_k127_3628736_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000005566 67.0
DTH2_k127_3636033_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.0000000000000000000000000000000000000000000000000000003654 198.0
DTH2_k127_3636033_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000001413 188.0
DTH2_k127_3636033_2 - - - - 0.000000000000000000000000001281 123.0
DTH2_k127_3677133_0 Male sterility protein K01784,K12454,K17947 - 5.1.3.10,5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
DTH2_k127_3677133_1 DNA binding protein K06930 - - 0.000000001678 63.0
DTH2_k127_3697713_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000001114 205.0
DTH2_k127_3697713_1 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000000000000000000008576 201.0
DTH2_k127_3697713_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000002327 170.0
DTH2_k127_3697713_3 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000007258 121.0
DTH2_k127_3697713_4 - - - - 0.0000000000000000000000001976 109.0
DTH2_k127_3697713_5 - - - - 0.0000000000000000000123 94.0
DTH2_k127_3763089_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 421.0
DTH2_k127_3763089_1 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 361.0
DTH2_k127_3763089_2 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001602 272.0
DTH2_k127_3763089_3 May catalyze a purine salvage reaction, the substrate is K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000000001143 203.0
DTH2_k127_3763089_4 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000002808 205.0
DTH2_k127_3763089_5 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.00000000000000000000000000000001312 129.0
DTH2_k127_3792193_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 4.282e-202 640.0
DTH2_k127_3792193_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 564.0
DTH2_k127_3792193_2 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 384.0
DTH2_k127_3792193_3 NADH-quinone oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001158 269.0
DTH2_k127_3792193_4 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001386 269.0
DTH2_k127_3792193_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000002857 205.0
DTH2_k127_3792193_6 NADH dehydrogenase K00335 - 1.6.5.3 0.000000000000000000000000000000000000000004278 157.0
DTH2_k127_3792193_7 Transcriptional regulator K07722 - - 0.000000000000000000000000002341 116.0
DTH2_k127_3792193_8 - - - - 0.000000000000000003112 91.0
DTH2_k127_3792193_9 but it may be involved in stabilization of the trimeric complex - - - 0.000000000006664 68.0
DTH2_k127_3793206_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.081e-224 708.0
DTH2_k127_3793206_1 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000002926 228.0
DTH2_k127_3793206_2 Competence-damaged protein K03743 - 3.5.1.42 0.0000000000000002168 81.0
DTH2_k127_3806342_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 370.0
DTH2_k127_3806342_1 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 312.0
DTH2_k127_3806342_2 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000456 246.0
DTH2_k127_3806342_3 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000692 216.0
DTH2_k127_3806342_4 PFAM Uncharacterised conserved protein UCP004962 - - - 0.000000000000000000000000009627 112.0
DTH2_k127_3806342_5 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000002184 112.0
DTH2_k127_3806342_6 BON domain - - - 0.00001744 53.0
DTH2_k127_3828961_0 Domain of unknown function (DUF4445) - - - 3.718e-214 678.0
DTH2_k127_3828961_1 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 576.0
DTH2_k127_3828961_2 corrinoid protein K14081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001373 256.0
DTH2_k127_3828961_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000001658 156.0
DTH2_k127_3828961_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2) K00197 - 2.1.1.245 0.000000000003146 74.0
DTH2_k127_3828961_5 Contains a Cobalamin (vitamin B12) biosynthesis domain, cobW domain - - - 0.0002378 45.0
DTH2_k127_3828961_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0002404 51.0
DTH2_k127_3856361_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000001483 208.0
DTH2_k127_3856361_1 - - - - 0.0000001696 61.0
DTH2_k127_3856361_2 regulatory protein, arsR - - - 0.00001046 53.0
DTH2_k127_386310_0 ATPases associated with a variety of cellular activities K00400,K02031,K02032 - - 2.672e-221 698.0
DTH2_k127_386310_1 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 427.0
DTH2_k127_386310_2 PFAM Methyl-coenzyme M reductase K03421 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 326.0
DTH2_k127_386310_3 Domain of unknown function (DUF4443) - - - 0.0000000000000000000000000000000000000000000000000000000000000003819 231.0
DTH2_k127_386310_4 Methanogenesis marker protein 5 - - - 0.0000000000000000000000000000000000000000000000000000000000001275 214.0
DTH2_k127_386310_5 TIGRFAM methanogenesis marker protein 6 - - - 0.0000000000000000000000000000000006826 136.0
DTH2_k127_386310_6 - - - - 0.00000000000007554 79.0
DTH2_k127_386310_7 - - - - 0.00000000005195 67.0
DTH2_k127_386310_8 BadF BadG BcrA BcrD - - - 0.00002191 47.0
DTH2_k127_3867902_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 9.691e-246 777.0
DTH2_k127_3867902_1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000004528 239.0
DTH2_k127_3867902_2 Protein of unknown function (DUF359) K09735 - - 0.000000000000000000004689 100.0
DTH2_k127_3867902_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000001072 96.0
DTH2_k127_3867902_4 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000009384 81.0
DTH2_k127_3867902_5 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000001539 78.0
DTH2_k127_3881519_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 350.0
DTH2_k127_3881519_1 TIGRFAM Outer membrane protein - - - 0.0000000005051 72.0
DTH2_k127_3881519_2 Carboxypeptidase regulatory-like domain - - - 0.0001026 55.0
DTH2_k127_3881519_3 ABC transporter K01996 - - 0.0007884 49.0
DTH2_k127_3887376_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001571 234.0
DTH2_k127_3887376_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000005768 191.0
DTH2_k127_3891021_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000006472 196.0
DTH2_k127_3891021_1 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000005486 76.0
DTH2_k127_3891021_2 helix_turn_helix ASNC type - - - 0.0000000000147 76.0
DTH2_k127_3891021_3 PFAM Uncharacterised BCR, COG1649 - - - 0.00006289 53.0
DTH2_k127_3925208_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 499.0
DTH2_k127_3925208_1 PFAM Phenylalanine and histidine ammonia-lyase K01745,K10775 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 4.3.1.24,4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 472.0
DTH2_k127_3925208_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 454.0
DTH2_k127_3925208_3 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002306 246.0
DTH2_k127_3925208_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000001825 164.0
DTH2_k127_3925208_5 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000000001869 85.0
DTH2_k127_3925208_6 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.0000000003414 75.0
DTH2_k127_3969355_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 504.0
DTH2_k127_3969355_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000865 136.0
DTH2_k127_3969355_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000003631 131.0
DTH2_k127_3969355_3 Aminotransferase class I and II K00639 - 2.3.1.29 0.000000000000000000000000000008944 120.0
DTH2_k127_3969355_4 transcriptional regulator - - - 0.0000000000000000000000006145 118.0
DTH2_k127_3969355_5 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000002458 87.0
DTH2_k127_3983548_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 4.764e-228 756.0
DTH2_k127_3983548_1 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 1.237e-198 669.0
DTH2_k127_3983548_10 major pilin protein fima - - - 0.0000000007293 61.0
DTH2_k127_3983548_2 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 4.659e-194 618.0
DTH2_k127_3983548_3 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 477.0
DTH2_k127_3983548_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 395.0
DTH2_k127_3983548_5 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004359 265.0
DTH2_k127_3983548_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007727 264.0
DTH2_k127_3983548_7 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
DTH2_k127_3983548_8 Cation efflux family K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000001641 247.0
DTH2_k127_3983548_9 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000001649 213.0
DTH2_k127_3996558_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 533.0
DTH2_k127_3996558_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000004736 180.0
DTH2_k127_3996558_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000006406 80.0
DTH2_k127_3996558_3 PFAM Protein kinase domain K08884 - 2.7.11.1 0.0000000005917 66.0
DTH2_k127_4001794_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 4.108e-203 650.0
DTH2_k127_4001794_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 532.0
DTH2_k127_4001794_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 291.0
DTH2_k127_4001794_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002092 273.0
DTH2_k127_4001794_4 COG1522 Transcriptional regulators K03718 - - 0.00000000000000000000000000000000000000000000007997 173.0
DTH2_k127_4001794_5 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000004264 82.0
DTH2_k127_4006070_0 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000001505 150.0
DTH2_k127_4006070_1 Uncharacterised protein family (UPF0147) K09721 - - 0.000000000000000000000000004215 117.0
DTH2_k127_4006070_2 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000001941 106.0
DTH2_k127_4006070_3 - - - - 0.00000000000000000362 84.0
DTH2_k127_4006070_4 Thioesterase superfamily K02614 - - 0.000000000004225 72.0
DTH2_k127_403086_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 297.0
DTH2_k127_403086_1 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000006706 149.0
DTH2_k127_403086_2 serine threonine protein kinase - - - 0.000000000000000000000000001705 123.0
DTH2_k127_403086_3 Rieske-like [2Fe-2S] domain - - - 0.0000000000001021 75.0
DTH2_k127_403086_4 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.000004199 50.0
DTH2_k127_403086_5 - - - - 0.000005219 58.0
DTH2_k127_403086_6 Homodimerisation domain of SGTA K16365 GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006620,GO:0006810,GO:0006886,GO:0006950,GO:0008104,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0015031,GO:0015833,GO:0016192,GO:0032947,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0072379,GO:0072380,GO:0072594,GO:0072599,GO:0072657,GO:0090150 - 0.00005568 52.0
DTH2_k127_4087742_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 610.0
DTH2_k127_4087742_1 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 399.0
DTH2_k127_4087742_10 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000003402 168.0
DTH2_k127_4087742_11 Heterodisulfide reductase subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000005808 115.0
DTH2_k127_4087742_12 Heterodisulfide reductase subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000008215 89.0
DTH2_k127_4087742_13 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.000000000001412 74.0
DTH2_k127_4087742_14 Transcriptional regulator K11924 - - 0.00000002635 58.0
DTH2_k127_4087742_15 zinc-ribbon domain - - - 0.0006472 48.0
DTH2_k127_4087742_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001214 280.0
DTH2_k127_4087742_3 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004266 259.0
DTH2_k127_4087742_4 Involved in the catabolism of quinolinic acid (QA) K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000008756 252.0
DTH2_k127_4087742_5 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
DTH2_k127_4087742_6 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000009625 210.0
DTH2_k127_4087742_7 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000001566 215.0
DTH2_k127_4087742_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000005153 203.0
DTH2_k127_4087742_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000001514 192.0
DTH2_k127_412214_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.805e-233 739.0
DTH2_k127_412214_1 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 381.0
DTH2_k127_412214_2 transcriptional regulator K07722 - - 0.00000000000000000000000000000001014 132.0
DTH2_k127_414194_0 Transglutaminase-like superfamily - - - 0.000000000000000000000001287 117.0
DTH2_k127_414194_1 - - - - 0.000000000000000000000004216 111.0
DTH2_k127_414194_2 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.00000001835 55.0
DTH2_k127_414194_3 DNA replication initiation - - - 0.0000002099 59.0
DTH2_k127_420210_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 405.0
DTH2_k127_420210_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 347.0
DTH2_k127_420210_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 310.0
DTH2_k127_420210_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007961 258.0
DTH2_k127_420210_4 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000107 259.0
DTH2_k127_420210_5 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000002814 175.0
DTH2_k127_420210_6 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000004684 181.0
DTH2_k127_420210_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000008567 94.0
DTH2_k127_420210_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000004962 72.0
DTH2_k127_4220229_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 334.0
DTH2_k127_4220229_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007483 260.0
DTH2_k127_4220229_10 - - - - 0.0000000000000000000001829 101.0
DTH2_k127_4220229_2 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000762 240.0
DTH2_k127_4220229_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001197 228.0
DTH2_k127_4220229_4 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000003029 183.0
DTH2_k127_4220229_5 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000008044 154.0
DTH2_k127_4220229_6 Fibronectin type III domain - - - 0.00000000000000000000000000000000001265 158.0
DTH2_k127_4220229_7 protein conserved in archaea - - - 0.000000000000000000000004221 108.0
DTH2_k127_4220229_8 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000008614 108.0
DTH2_k127_4220229_9 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.000000000000000000000105 104.0
DTH2_k127_4251469_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 7.582e-243 755.0
DTH2_k127_4251469_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.797e-221 695.0
DTH2_k127_4251469_10 Archaeal Type IV pilin, N-terminal - - - 0.000000001499 69.0
DTH2_k127_4251469_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 482.0
DTH2_k127_4251469_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
DTH2_k127_4251469_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000005408 208.0
DTH2_k127_4251469_5 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000216 181.0
DTH2_k127_4251469_6 TIGRFAM adenylyl cyclase CyaB K05873 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 4.6.1.1 0.000000000000000000000000000000000001491 147.0
DTH2_k127_4251469_7 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000000000000000000000000000226 140.0
DTH2_k127_4251469_8 CAAX protease self-immunity - - - 0.000000000000000000000000000000922 137.0
DTH2_k127_4251469_9 Belongs to the UPF0201 family K09736 - - 0.0000000000000001909 84.0
DTH2_k127_4285551_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 1.116e-258 822.0
DTH2_k127_4285551_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.853e-210 670.0
DTH2_k127_4285551_10 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000007828 128.0
DTH2_k127_4285551_11 Belongs to the SfsA family K06206 - - 0.00000000000000000000031 106.0
DTH2_k127_4285551_12 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000001024 85.0
DTH2_k127_4285551_13 transcription regulator activity - - - 0.000000000000001371 85.0
DTH2_k127_4285551_14 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.0000000000001938 73.0
DTH2_k127_4285551_15 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.000000000006939 76.0
DTH2_k127_4285551_16 Protein of unknown function (DUF3795) - - - 0.0006682 47.0
DTH2_k127_4285551_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 608.0
DTH2_k127_4285551_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 584.0
DTH2_k127_4285551_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K03885,K17870 - 1.6.3.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 505.0
DTH2_k127_4285551_5 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 467.0
DTH2_k127_4285551_6 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 347.0
DTH2_k127_4285551_7 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 292.0
DTH2_k127_4285551_8 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.00000000000000000000000000000000000000006712 159.0
DTH2_k127_4285551_9 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000002334 136.0
DTH2_k127_4347302_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 575.0
DTH2_k127_4347302_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000005886 156.0
DTH2_k127_4374574_0 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 393.0
DTH2_k127_4374574_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000002772 188.0
DTH2_k127_4374574_2 DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000001011 172.0
DTH2_k127_4374574_3 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000001286 155.0
DTH2_k127_4374574_4 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000002404 136.0
DTH2_k127_4374574_5 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000002539 128.0
DTH2_k127_4407179_0 Uroporphyrinogen decarboxylase (URO-D) K14082 - 2.1.1.247 0.000000000000000000000000000000000000000000000000000000000000001875 230.0
DTH2_k127_4407179_1 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000002414 166.0
DTH2_k127_4407179_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000001057 128.0
DTH2_k127_4419798_0 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005537 267.0
DTH2_k127_4419798_1 Drug metabolite transporter - - - 0.00001257 56.0
DTH2_k127_4429657_0 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000003008 207.0
DTH2_k127_4429657_1 exonuclease K07502 - - 0.00000000000000000000000000000000000000000000005242 179.0
DTH2_k127_4429657_2 B12 binding domain - - - 0.0000000000000000000000000000000003107 136.0
DTH2_k127_4429657_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000001035 88.0
DTH2_k127_4461099_0 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000007194 130.0
DTH2_k127_4461099_1 Major Facilitator Superfamily - - - 0.0000000000003 78.0
DTH2_k127_4465100_0 Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 337.0
DTH2_k127_4465100_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000007602 209.0
DTH2_k127_4465100_2 Belongs to the glutamate synthase family - - - 0.00009953 48.0
DTH2_k127_4478675_0 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 505.0
DTH2_k127_4478675_1 PFAM Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 410.0
DTH2_k127_4478675_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001971 265.0
DTH2_k127_4478675_3 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000007481 223.0
DTH2_k127_4478675_4 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000009493 171.0
DTH2_k127_4478675_5 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000704 122.0
DTH2_k127_4478675_6 helix_turn_helix ASNC type - - - 0.00004294 54.0
DTH2_k127_4478675_8 sequence-specific DNA binding - - - 0.00005748 53.0
DTH2_k127_4584707_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.36e-209 661.0
DTH2_k127_4584707_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 417.0
DTH2_k127_4584707_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000006377 151.0
DTH2_k127_4601654_0 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 482.0
DTH2_k127_4601654_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000001636 132.0
DTH2_k127_4601654_2 Serine aminopeptidase, S33 - - - 0.0000000001549 66.0
DTH2_k127_4602743_0 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 505.0
DTH2_k127_4602743_1 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000004371 226.0
DTH2_k127_4657494_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 411.0
DTH2_k127_4657494_1 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 376.0
DTH2_k127_4666701_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000165 277.0
DTH2_k127_4666701_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000001857 175.0
DTH2_k127_4666701_2 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000006629 111.0
DTH2_k127_4666701_3 Belongs to the Fur family K09825 - - 0.0000000000000000001675 94.0
DTH2_k127_4666701_4 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000008475 53.0
DTH2_k127_4752325_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000004537 208.0
DTH2_k127_4752325_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000006465 171.0
DTH2_k127_4752325_2 Belongs to the peptidase S51 family - - - 0.000001632 57.0
DTH2_k127_4800351_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 9.419e-221 704.0
DTH2_k127_4800351_1 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 369.0
DTH2_k127_4800351_2 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000001671 168.0
DTH2_k127_4800351_3 nitroreductase - - - 0.00000000000000000000000000000000000000000003764 168.0
DTH2_k127_4800351_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000000001103 154.0
DTH2_k127_4800351_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000001551 135.0
DTH2_k127_4800351_6 - - - - 0.0000003441 56.0
DTH2_k127_4800351_7 Flavodoxin domain - - - 0.000222 48.0
DTH2_k127_4815568_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 5.175e-249 782.0
DTH2_k127_4815568_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 3.164e-232 739.0
DTH2_k127_4815568_2 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000009191 162.0
DTH2_k127_4840289_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 375.0
DTH2_k127_4840289_1 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 313.0
DTH2_k127_4840289_2 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000229 48.0
DTH2_k127_4881272_0 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 289.0
DTH2_k127_4881272_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000006624 159.0
DTH2_k127_4881272_2 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000001974 106.0
DTH2_k127_4881272_3 Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000002819 74.0
DTH2_k127_4884992_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 461.0
DTH2_k127_4884992_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003686 276.0
DTH2_k127_4884992_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002288 256.0
DTH2_k127_4884992_3 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005825 259.0
DTH2_k127_4884992_4 Major facilitator Superfamily K05820 - - 0.0000000000000000006834 89.0
DTH2_k127_4884992_5 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000002917 87.0
DTH2_k127_4899932_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000001666 244.0
DTH2_k127_4899932_1 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000289 229.0
DTH2_k127_4899932_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000005154 164.0
DTH2_k127_4899932_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000003119 71.0
DTH2_k127_4911086_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 411.0
DTH2_k127_4911086_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000001978 230.0
DTH2_k127_4911086_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000006705 211.0
DTH2_k127_4911086_3 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000001014 166.0
DTH2_k127_4911086_4 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000000000000001762 151.0
DTH2_k127_4911086_5 coproporphyrinogen III oxidase - - - 0.0000000000000000000000000000000000000008421 165.0
DTH2_k127_4911086_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000000002231 120.0
DTH2_k127_4911086_7 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000001592 96.0
DTH2_k127_4954875_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 612.0
DTH2_k127_4954875_1 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 395.0
DTH2_k127_4954875_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 384.0
DTH2_k127_4954875_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 375.0
DTH2_k127_4954875_4 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 307.0
DTH2_k127_4954875_5 phosphoesterase RecJ domain protein K07463 - - 0.0000000000000000000000001343 110.0
DTH2_k127_4954875_6 Pfam:DUF552 K09152 - - 0.0000000000000000000000002042 110.0
DTH2_k127_4954875_7 PAS domain K02488 - 2.7.7.65 0.00000000001789 76.0
DTH2_k127_4954875_8 Exonuclease - GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0010494,GO:0032991,GO:0035770,GO:0036464,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0002089 49.0
DTH2_k127_4959033_0 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 387.0
DTH2_k127_4959033_1 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000002587 252.0
DTH2_k127_4959033_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000001184 183.0
DTH2_k127_4959033_3 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000004678 184.0
DTH2_k127_4959033_4 cell redox homeostasis - - - 0.00000000000000006432 85.0
DTH2_k127_4959033_5 Flavin reductase like domain - - - 0.000000005659 65.0
DTH2_k127_4959033_6 ferredoxin-thioredoxin reductase activity - - - 0.00000001036 64.0
DTH2_k127_4959033_7 Pathogenicity locus - - - 0.0001123 48.0
DTH2_k127_4959033_8 Lipoate-protein ligase a K03800 - 6.3.1.20 0.000186 48.0
DTH2_k127_4967718_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000006625 223.0
DTH2_k127_4967718_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000003793 192.0
DTH2_k127_4967718_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000002215 156.0
DTH2_k127_4994786_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 455.0
DTH2_k127_4994786_1 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
DTH2_k127_4994786_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 333.0
DTH2_k127_4994786_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000005455 259.0
DTH2_k127_4994786_4 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000000000000000000000000681 201.0
DTH2_k127_4994786_5 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001257 121.0
DTH2_k127_5007280_0 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000001483 199.0
DTH2_k127_5007280_1 PFAM Xylose isomerase domain protein TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000006179 199.0
DTH2_k127_5007280_2 Participates in both transcription termination and antitermination K02600 - - 0.0001261 49.0
DTH2_k127_5027214_0 Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 360.0
DTH2_k127_5027214_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
DTH2_k127_5027214_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000002752 222.0
DTH2_k127_5027214_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000007784 218.0
DTH2_k127_5027214_4 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000002616 173.0
DTH2_k127_5027214_5 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000002587 142.0
DTH2_k127_5027214_6 - - - - 0.000000000005048 73.0
DTH2_k127_5027214_7 helix_turn_helix ASNC type K06154 - - 0.000000001043 59.0
DTH2_k127_5027214_8 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00003588 48.0
DTH2_k127_508157_0 PFAM Radical SAM K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 407.0
DTH2_k127_508157_1 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000001853 136.0
DTH2_k127_508157_2 - - - - 0.00000000000000003459 85.0
DTH2_k127_508157_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000392 69.0
DTH2_k127_508376_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1029.0
DTH2_k127_508376_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 579.0
DTH2_k127_508376_10 - - - - 0.00000000000000000000000002006 117.0
DTH2_k127_508376_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000007564 96.0
DTH2_k127_508376_12 - - - - 0.00000000005378 67.0
DTH2_k127_508376_13 RNA-binding protein involved in rRNA processing K07569 - - 0.000005756 52.0
DTH2_k127_508376_14 metallopeptidase activity - - - 0.0001403 55.0
DTH2_k127_508376_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 571.0
DTH2_k127_508376_3 Helix-turn-helix XRE-family like proteins K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 344.0
DTH2_k127_508376_4 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 319.0
DTH2_k127_508376_5 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000004259 264.0
DTH2_k127_508376_6 pfkB family carbohydrate kinase K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000002601 244.0
DTH2_k127_508376_7 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001069 130.0
DTH2_k127_508376_8 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.00000000000000000000000000000001455 135.0
DTH2_k127_508376_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000001333 124.0
DTH2_k127_5103592_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 561.0
DTH2_k127_5103592_1 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 464.0
DTH2_k127_5103592_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 361.0
DTH2_k127_5103592_3 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001129 289.0
DTH2_k127_5103592_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005318 273.0
DTH2_k127_5103592_5 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000313 183.0
DTH2_k127_5103592_6 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000005889 171.0
DTH2_k127_5103592_7 PFAM TrkA-N domain K10716 - - 0.0000000000000000000000000000003599 134.0
DTH2_k127_5103592_8 COG0003 Oxyanion-translocating ATPase K01551 - 3.6.3.16 0.00000000000001097 79.0
DTH2_k127_5103592_9 membrane - - - 0.0000000157 63.0
DTH2_k127_5134927_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 409.0
DTH2_k127_5134927_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000107 264.0
DTH2_k127_5134927_2 Belongs to the thiolase family K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.00000000000000000000000000001415 119.0
DTH2_k127_5135701_0 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001645 245.0
DTH2_k127_5135701_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001925 213.0
DTH2_k127_5135701_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000002097 96.0
DTH2_k127_5135701_11 Ribosomal L29 protein K02904 - - 0.0000006418 51.0
DTH2_k127_5135701_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000293 211.0
DTH2_k127_5135701_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003298 208.0
DTH2_k127_5135701_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001981 207.0
DTH2_k127_5135701_5 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001591 162.0
DTH2_k127_5135701_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000003485 153.0
DTH2_k127_5135701_7 ribosomal protein L24 K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001886 141.0
DTH2_k127_5135701_8 structural constituent of ribosome K02912 - - 0.000000000000000000000000000000001077 142.0
DTH2_k127_5135701_9 ribosomal protein S14 K02954 - - 0.00000000000000000001614 94.0
DTH2_k127_5143707_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 582.0
DTH2_k127_5143707_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 533.0
DTH2_k127_5143707_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005494 270.0
DTH2_k127_5143707_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000002558 223.0
DTH2_k127_5143707_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000008457 73.0
DTH2_k127_514546_0 Fumarate reductase succinate dehydrogenase flavoprotein K18209 - 1.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 438.0
DTH2_k127_514546_1 fumarate reductase K18210 - 1.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
DTH2_k127_5166735_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.00000000000000000000000000000000000000000000000000000000000007688 226.0
DTH2_k127_5166735_1 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000008725 150.0
DTH2_k127_5166735_2 - - - - 0.00002705 49.0
DTH2_k127_5200009_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 505.0
DTH2_k127_5200009_1 - - - - 0.00000000000000000000000000000000003764 140.0
DTH2_k127_5200009_2 - - - - 0.00000000000000000000000000000006063 127.0
DTH2_k127_5316861_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 550.0
DTH2_k127_5316861_1 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 303.0
DTH2_k127_5316861_2 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000000001411 220.0
DTH2_k127_5316861_3 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000006096 132.0
DTH2_k127_5316861_4 sulfur carrier activity K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000000022 94.0
DTH2_k127_5316861_5 - - - - 0.0000000000002051 82.0
DTH2_k127_5316861_6 - - - - 0.000005137 58.0
DTH2_k127_5322251_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 2.139e-209 680.0
DTH2_k127_5322251_1 Threonine synthase K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.0000000000000000000000000000000000000000000000000001555 188.0
DTH2_k127_5322251_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000003135 164.0
DTH2_k127_5322251_3 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000002571 138.0
DTH2_k127_5356331_0 Type II/IV secretion system protein K07332 - - 1.283e-221 701.0
DTH2_k127_5356331_1 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 379.0
DTH2_k127_5356331_2 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 305.0
DTH2_k127_5356331_3 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001063 280.0
DTH2_k127_5356331_4 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000007063 246.0
DTH2_k127_5356331_5 toxin activity - - - 0.0000000000000000000000001999 118.0
DTH2_k127_5356331_6 - - - - 0.000000000000000000000007517 107.0
DTH2_k127_5375114_0 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 482.0
DTH2_k127_5375114_1 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000003031 226.0
DTH2_k127_5375114_2 TIGRFAM segregation and condensation protein B K06024 - - 0.00000000000000000000000000000000000000008779 156.0
DTH2_k127_5375114_3 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000002406 165.0
DTH2_k127_5375114_4 snRNP Sm proteins K04796 - - 0.00000000000000000000000729 102.0
DTH2_k127_5375114_5 chromosome segregation and condensation protein ScpA K05896 - - 0.00001436 49.0
DTH2_k127_5425419_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.076e-231 734.0
DTH2_k127_5425419_1 Nickel-dependent hydrogenase K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 1.521e-195 621.0
DTH2_k127_5425419_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.00000000000000000001935 93.0
DTH2_k127_5425419_11 flavodoxin nitric oxide synthase - - - 0.000000000132 70.0
DTH2_k127_5425419_2 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 391.0
DTH2_k127_5425419_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 397.0
DTH2_k127_5425419_4 4Fe-4S ferredoxin iron-sulfur binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002034 259.0
DTH2_k127_5425419_5 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000001002 238.0
DTH2_k127_5425419_6 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000003954 245.0
DTH2_k127_5425419_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002512 224.0
DTH2_k127_5425419_8 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000002389 162.0
DTH2_k127_5425419_9 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000000000003545 128.0
DTH2_k127_5429648_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 333.0
DTH2_k127_5429648_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000739 103.0
DTH2_k127_5429648_2 - K00960 - 2.7.7.6 0.0000000000000000001297 89.0
DTH2_k127_5430879_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 524.0
DTH2_k127_5430879_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 499.0
DTH2_k127_5430879_2 Belongs to the HMG-CoA reductase family K00021,K00054 GO:0003674,GO:0003824,GO:0004420,GO:0006629,GO:0006694,GO:0006720,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 1.1.1.34,1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 439.0
DTH2_k127_5430879_3 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000001386 206.0
DTH2_k127_5430879_4 Kelch motif - - - 0.000000000003871 69.0
DTH2_k127_5430879_5 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00002032 49.0
DTH2_k127_5442361_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.227e-228 720.0
DTH2_k127_5442361_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.901e-203 640.0
DTH2_k127_5442361_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000009223 184.0
DTH2_k127_5442361_3 - - - - 0.00000000000005382 78.0
DTH2_k127_5442361_4 glucosylceramidase activity - - - 0.000000000004438 71.0
DTH2_k127_5442361_5 Small-conductance mechanosensitive channel K05802 - - 0.0000002434 62.0
DTH2_k127_5452456_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.099e-206 654.0
DTH2_k127_5452456_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001624 280.0
DTH2_k127_5452456_2 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000343 185.0
DTH2_k127_5452456_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000214 162.0
DTH2_k127_5452456_4 Transcriptional regulator PadR-like family - - - 0.0000000000000316 75.0
DTH2_k127_5452456_5 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.00000005794 53.0
DTH2_k127_5466544_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1123.0
DTH2_k127_5466544_1 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 474.0
DTH2_k127_5466544_2 Diacylglycerol kinase catalytic domain K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 343.0
DTH2_k127_5466544_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000009362 227.0
DTH2_k127_5466544_4 TIGRFAM indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000001137 183.0
DTH2_k127_5466544_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000008394 183.0
DTH2_k127_5466544_6 - - - - 0.00002357 51.0
DTH2_k127_5474372_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.115e-291 908.0
DTH2_k127_5474372_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000005041 224.0
DTH2_k127_5474372_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000001051 207.0
DTH2_k127_552645_0 Domain of unknown function DUF87 K06915,K19172 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 511.0
DTH2_k127_552645_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 318.0
DTH2_k127_552645_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 313.0
DTH2_k127_552645_3 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000001502 255.0
DTH2_k127_552645_4 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000005194 166.0
DTH2_k127_552645_5 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000007185 156.0
DTH2_k127_552645_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000001849 132.0
DTH2_k127_5531231_0 DEAD_2 K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000001105 207.0
DTH2_k127_5531231_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000001012 176.0
DTH2_k127_5588575_0 Belongs to the UPF0292 family - - - 0.000000000000000000003674 99.0
DTH2_k127_5588575_1 Belongs to the UPF0235 family K09131 - - 0.000000000000000009071 86.0
DTH2_k127_5588575_2 - - - - 0.0000000002751 70.0
DTH2_k127_5588575_3 protein conserved in archaea K09723 - - 0.0006339 51.0
DTH2_k127_5600657_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 381.0
DTH2_k127_5600657_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004567 274.0
DTH2_k127_5600657_2 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000003122 139.0
DTH2_k127_5600657_3 Thioredoxin K03671 - - 0.00000000000001432 80.0
DTH2_k127_5600657_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000004447 82.0
DTH2_k127_5600657_5 ATPases associated with a variety of cellular activities K02003 - - 0.000004933 49.0
DTH2_k127_5615026_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 612.0
DTH2_k127_5685453_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 447.0
DTH2_k127_5685453_1 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000002288 231.0
DTH2_k127_5685453_2 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000000000006096 231.0
DTH2_k127_5685453_3 Belongs to the UPF0248 family K09715 - - 0.00000000008097 65.0
DTH2_k127_5685453_4 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000003189 61.0
DTH2_k127_5716389_0 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 368.0
DTH2_k127_5716389_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000004112 190.0
DTH2_k127_5716389_2 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000004717 171.0
DTH2_k127_5716389_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000001842 157.0
DTH2_k127_5716389_4 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000003526 117.0
DTH2_k127_5716389_5 helicase K07464,K10844 - 3.1.12.1,3.6.4.12 0.000000000000000000107 95.0
DTH2_k127_5716389_6 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000003327 58.0
DTH2_k127_5716389_7 - - - - 0.00004465 50.0
DTH2_k127_5753467_0 DNA binding protein K06930 - - 0.0000000000000000000000001613 116.0
DTH2_k127_5753467_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0003852 45.0
DTH2_k127_5754329_0 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 302.0
DTH2_k127_5754329_1 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000001608 188.0
DTH2_k127_5754329_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000001644 184.0
DTH2_k127_5754329_3 Cytidylyltransferase K19712 - 2.7.7.62 0.0000000000000000000000000000001647 132.0
DTH2_k127_5754329_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000274 55.0
DTH2_k127_5788945_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 450.0
DTH2_k127_5788945_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 385.0
DTH2_k127_5788945_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 374.0
DTH2_k127_5788945_4 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000008891 93.0
DTH2_k127_5788945_5 methyltransferase - - - 0.0000000000000004738 88.0
DTH2_k127_5794418_0 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 396.0
DTH2_k127_5794418_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 368.0
DTH2_k127_5794418_2 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000003781 172.0
DTH2_k127_5794418_3 4-epimerase K01628 - 4.1.2.17 0.000000000000000000000000000000000002662 147.0
DTH2_k127_5794418_4 Uncharacterized protein family UPF0016 - - - 0.0002151 49.0
DTH2_k127_5806519_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 425.0
DTH2_k127_5806519_1 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000284 249.0
DTH2_k127_5930896_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 356.0
DTH2_k127_5930896_1 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004127 286.0
DTH2_k127_5930896_2 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000005331 115.0
DTH2_k127_5930896_3 LemA family K03744 - - 0.000000000000000000000004098 110.0
DTH2_k127_5930896_4 Methanol dehydrogenase K06872 - - 0.0000000000000002713 88.0
DTH2_k127_5930896_5 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00006128 51.0
DTH2_k127_593287_0 Hydantoinaseoxoprolinase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 404.0
DTH2_k127_593287_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 394.0
DTH2_k127_593287_2 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 289.0
DTH2_k127_593287_3 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000003279 209.0
DTH2_k127_593287_4 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000003632 124.0
DTH2_k127_593287_5 regulatory protein, arsR - - - 0.000000002076 58.0
DTH2_k127_6000849_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.9e-268 839.0
DTH2_k127_6000849_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 601.0
DTH2_k127_6000849_2 DNA gyrase topoisomerase IV, subunit A K02469 GO:0005575,GO:0005622,GO:0005623,GO:0009330,GO:0032991,GO:0044424,GO:0044464 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000001004 217.0
DTH2_k127_6033463_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 352.0
DTH2_k127_6033463_1 Glycosyltransferase like family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008222 278.0
DTH2_k127_6033463_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000006768 212.0
DTH2_k127_6033463_3 Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000007786 169.0
DTH2_k127_6033463_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000002638 168.0
DTH2_k127_6033463_5 Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides - - - 0.000000000000000000000000000002394 130.0
DTH2_k127_6033463_6 polysaccharide biosynthetic process - - - 0.000000000000000000000000002173 128.0
DTH2_k127_6087583_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 520.0
DTH2_k127_6087583_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 331.0
DTH2_k127_6087583_10 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000001391 156.0
DTH2_k127_6087583_11 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000297 145.0
DTH2_k127_6087583_12 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000001347 140.0
DTH2_k127_6087583_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003151 143.0
DTH2_k127_6087583_14 PRC-barrel domain - - - 0.000000000000000000003607 95.0
DTH2_k127_6087583_15 - - - - 0.000000009092 63.0
DTH2_k127_6087583_2 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005541 252.0
DTH2_k127_6087583_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
DTH2_k127_6087583_4 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000005554 211.0
DTH2_k127_6087583_5 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000005233 185.0
DTH2_k127_6087583_6 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000002883 166.0
DTH2_k127_6087583_7 Thioredoxin reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000917 164.0
DTH2_k127_6087583_8 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000001177 168.0
DTH2_k127_6087583_9 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000001072 161.0
DTH2_k127_6120742_0 tRNA synthetases class I (C) catalytic domain K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 569.0
DTH2_k127_6120742_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 365.0
DTH2_k127_6120742_2 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000008307 248.0
DTH2_k127_6120742_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000001852 227.0
DTH2_k127_6120742_4 Iron dependent K03709 - - 0.000000000000000000000004479 104.0
DTH2_k127_6120742_5 Peptidase family M28 - - - 0.0000000000003187 83.0
DTH2_k127_6120742_6 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000003247 66.0
DTH2_k127_6132056_0 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 366.0
DTH2_k127_6132056_1 Oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000002012 157.0
DTH2_k127_6132056_2 Biotin-requiring enzyme - - - 0.000000000000000001352 92.0
DTH2_k127_6195591_0 COG0531 Amino acid transporters - - - 0.00000000000000000000000000000000000000000000000000000004116 213.0
DTH2_k127_6195591_1 DHHA1 domain K07463 - - 0.0000000003633 71.0
DTH2_k127_6208673_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 408.0
DTH2_k127_6208673_1 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 372.0
DTH2_k127_6208673_2 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002584 277.0
DTH2_k127_6208673_3 Mechanosensitive ion channel K03442,K05802,K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003603 278.0
DTH2_k127_6208673_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000004321 228.0
DTH2_k127_6208673_5 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.00000000000000000000000000000000000000001436 164.0
DTH2_k127_6240239_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1252.0
DTH2_k127_6240239_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001469 265.0
DTH2_k127_6240239_2 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000004054 215.0
DTH2_k127_6240239_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00004314 50.0
DTH2_k127_6288161_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 3.918e-209 667.0
DTH2_k127_6288161_1 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 387.0
DTH2_k127_6288161_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000002118 273.0
DTH2_k127_6288161_3 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000002225 151.0
DTH2_k127_6288161_4 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000144 126.0
DTH2_k127_6292708_0 Belongs to the peptidase S16 family - - - 3.802e-264 835.0
DTH2_k127_6313108_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 529.0
DTH2_k127_6313108_1 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 384.0
DTH2_k127_6315609_0 - - - - 0.0000000000000000000000000000000000000000000000000000002849 202.0
DTH2_k127_6315609_1 LysE type translocator - - - 0.000000000000000000000000000000000001325 147.0
DTH2_k127_6315609_2 - - - - 0.00000000000000000000000001961 124.0
DTH2_k127_6315609_3 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000005184 88.0
DTH2_k127_6327407_0 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001084 317.0
DTH2_k127_6327407_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000834 138.0
DTH2_k127_6332765_0 PFAM NADH-ubiquinone oxidoreductase chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 347.0
DTH2_k127_6332765_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 329.0
DTH2_k127_6332765_10 NADH ubiquinone oxidoreductase - - - 0.00000000000000000000007819 102.0
DTH2_k127_6332765_11 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000003851 83.0
DTH2_k127_6332765_12 endonuclease activity K07451 - - 0.00000000001283 72.0
DTH2_k127_6332765_13 - - - - 0.00001458 51.0
DTH2_k127_6332765_14 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00004407 50.0
DTH2_k127_6332765_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002098 248.0
DTH2_k127_6332765_3 PFAM respiratory-chain NADH dehydrogenase subunit 1 K14087 - - 0.000000000000000000000000000000000000000000000000000000000000001189 230.0
DTH2_k127_6332765_4 COG0471 Di- and tricarboxylate transporters K14445 - - 0.0000000000000000000000000000000000000000000000000000000003572 221.0
DTH2_k127_6332765_5 PFAM NADH ubiquinone oxidoreductase, 20 K00331,K14088 - 1.6.5.3 0.000000000000000000000000000000000000000000000001292 181.0
DTH2_k127_6332765_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000307 141.0
DTH2_k127_6332765_7 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000001722 135.0
DTH2_k127_6332765_8 FR47-like protein - - - 0.00000000000000000000000005449 112.0
DTH2_k127_6332765_9 Redoxin K03386 - 1.11.1.15 0.00000000000000000000002165 107.0
DTH2_k127_6357697_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 321.0
DTH2_k127_6357697_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
DTH2_k127_6357697_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000001191 186.0
DTH2_k127_6357697_3 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000292 115.0
DTH2_k127_6357697_4 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000009303 98.0
DTH2_k127_6385287_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000002972 145.0
DTH2_k127_6385287_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.000000000000001306 84.0
DTH2_k127_6385287_2 PFAM NADPH-dependent FMN reductase - - - 0.000002104 50.0
DTH2_k127_6402233_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 486.0
DTH2_k127_6402233_1 PFAM Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 475.0
DTH2_k127_6402233_2 Universal stress protein family - - - 0.000001088 60.0
DTH2_k127_6402233_3 alpha-ribazole phosphatase activity K02226,K07814 - 3.1.3.73 0.000001449 58.0
DTH2_k127_6402233_4 Glycosyl transferase, family 2 - - - 0.00002082 56.0
DTH2_k127_6414395_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 501.0
DTH2_k127_6414395_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 345.0
DTH2_k127_6463565_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000001041 145.0
DTH2_k127_6463565_1 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000001711 115.0
DTH2_k127_6463565_2 - - - - 0.00000001655 66.0
DTH2_k127_6464341_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 609.0
DTH2_k127_6464341_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 517.0
DTH2_k127_6464341_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000245 112.0
DTH2_k127_6464341_11 - - - - 0.00000000000000000000000339 113.0
DTH2_k127_6464341_12 Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.000000000000009542 82.0
DTH2_k127_6464341_13 ubiquitin-conjugating enzyme K13960 GO:0000209,GO:0003674,GO:0003682,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006513,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0033554,GO:0034641,GO:0035519,GO:0036211,GO:0036297,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044314,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0051865,GO:0061630,GO:0061631,GO:0061650,GO:0061659,GO:0070013,GO:0070534,GO:0070647,GO:0070936,GO:0070979,GO:0071704,GO:0085020,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.2.23 0.0000000002106 68.0
DTH2_k127_6464341_14 luxR family - - - 0.0008379 49.0
DTH2_k127_6464341_2 COG0530 Ca2 Na antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 419.0
DTH2_k127_6464341_3 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 349.0
DTH2_k127_6464341_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000002544 182.0
DTH2_k127_6464341_5 SIS domain K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000001627 168.0
DTH2_k127_6464341_6 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000002414 166.0
DTH2_k127_6464341_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000212 151.0
DTH2_k127_6464341_8 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000126 147.0
DTH2_k127_6464341_9 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000002131 116.0
DTH2_k127_6490968_0 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
DTH2_k127_6490968_1 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000004664 202.0
DTH2_k127_6490968_2 - - - - 0.0000000000000000003326 90.0
DTH2_k127_6490968_3 2TM domain - - - 0.000001025 55.0
DTH2_k127_6490968_4 helix_turn_helix ASNC type K03719 - - 0.00009984 53.0
DTH2_k127_6539114_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 374.0
DTH2_k127_6539114_1 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 373.0
DTH2_k127_6539114_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 302.0
DTH2_k127_6539114_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
DTH2_k127_6539114_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000001899 102.0
DTH2_k127_6552555_0 Glycosyl transferase 4-like - - - 0.000001799 55.0
DTH2_k127_6552555_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0002903 52.0
DTH2_k127_65887_0 Patch-forming domain C2 of tRNA-guanine transglycosylase K07557 GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 351.0
DTH2_k127_65887_1 acetyl-CoA hydrolase transferase - - - 0.0000000000000000000000000000000000000000000000000003572 192.0
DTH2_k127_65887_2 COG1226 Kef-type K transport systems K10716 - - 0.0000000000000000000000000000005947 131.0
DTH2_k127_6597066_0 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 5.932e-199 628.0
DTH2_k127_6597066_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 417.0
DTH2_k127_6597066_10 helix_turn_helix ASNC type - - - 0.000000000002005 74.0
DTH2_k127_6597066_2 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 390.0
DTH2_k127_6597066_3 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 285.0
DTH2_k127_6597066_4 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001085 266.0
DTH2_k127_6597066_5 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000002153 219.0
DTH2_k127_6597066_6 PFAM TfuA domain protein, core - - - 0.00000000000000000000000000000000000000000000000263 181.0
DTH2_k127_6597066_7 Metal-dependent hydrolase, beta-lactamase superfamily II K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000002632 175.0
DTH2_k127_6597066_8 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000000000000000000014 139.0
DTH2_k127_6597066_9 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.00000000000000000000000000000004617 130.0
DTH2_k127_666472_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 1.868e-247 771.0
DTH2_k127_666472_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001232 270.0
DTH2_k127_666472_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001126 259.0
DTH2_k127_666472_3 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000002213 124.0
DTH2_k127_666472_4 ABC-2 family transporter protein K01992 - - 0.00000000000006745 82.0
DTH2_k127_666472_5 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000007992 63.0
DTH2_k127_666472_6 sequence-specific DNA binding - - - 0.00000068 58.0
DTH2_k127_666472_7 - - - - 0.0006629 48.0
DTH2_k127_6668148_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009568 240.0
DTH2_k127_6668148_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000004918 181.0
DTH2_k127_6668148_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000006263 173.0
DTH2_k127_6668148_3 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000007084 136.0
DTH2_k127_6714986_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 490.0
DTH2_k127_6802765_0 Fibronectin type III domain K12567 - 2.7.11.1 2.924e-259 876.0
DTH2_k127_6802765_1 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000008571 164.0
DTH2_k127_6802765_2 chlorophyll binding - - - 0.00000000000006963 86.0
DTH2_k127_6802765_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000001448 82.0
DTH2_k127_6802765_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000003626 54.0
DTH2_k127_6802765_5 TonB-linked outer membrane protein, SusC RagA family - - - 0.0002984 50.0
DTH2_k127_6803356_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 403.0
DTH2_k127_6803356_1 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 374.0
DTH2_k127_6803356_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 298.0
DTH2_k127_6803356_3 Transketolase K00615 - 2.2.1.1 0.0000000000000000000001121 98.0
DTH2_k127_6803356_4 Domain of unknown function (DUF4129) - - - 0.0000003393 61.0
DTH2_k127_6959198_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 385.0
DTH2_k127_6959198_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000003398 251.0
DTH2_k127_6959198_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000002344 121.0
DTH2_k127_7016803_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000002302 245.0
DTH2_k127_7016803_1 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000105 197.0
DTH2_k127_7016803_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000001919 113.0
DTH2_k127_7016803_3 Roadblock LC7 family protein K06945,K07131 - - 0.00000000004159 68.0
DTH2_k127_7016803_4 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000001881 60.0
DTH2_k127_704802_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 293.0
DTH2_k127_704802_1 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000002683 245.0
DTH2_k127_704802_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
DTH2_k127_7069451_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 352.0
DTH2_k127_7069451_1 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 347.0
DTH2_k127_7182979_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 393.0
DTH2_k127_7182979_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000001072 118.0
DTH2_k127_7182979_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000006146 78.0
DTH2_k127_7206031_0 Heat shock 70 kDa protein K04043 - - 7.107e-271 848.0
DTH2_k127_7206031_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 5.326e-233 732.0
DTH2_k127_7206031_2 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 329.0
DTH2_k127_7206031_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 289.0
DTH2_k127_7206031_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000003182 141.0
DTH2_k127_7206031_5 Helix-turn-helix XRE-family like proteins K03627 - - 0.00000000000000000000000000000137 128.0
DTH2_k127_7206031_6 protein conserved in archaea - - - 0.0000000000000000000000002839 111.0
DTH2_k127_7206898_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 596.0
DTH2_k127_7206898_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000003464 254.0
DTH2_k127_7206898_2 Sigma-70 region 2 - - - 0.0003208 52.0
DTH2_k127_7215378_0 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 410.0
DTH2_k127_7215378_1 DNA polymerase type-B family K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 307.0
DTH2_k127_7249222_0 HMGL-like K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 390.0
DTH2_k127_7249222_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 315.0
DTH2_k127_7249222_2 - - - - 0.0000000001785 68.0
DTH2_k127_7249222_3 PIN domain - - - 0.000000336 61.0
DTH2_k127_7253567_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 344.0
DTH2_k127_7253567_1 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 312.0
DTH2_k127_7253567_2 Restriction endonuclease - - - 0.000000000000000000000000000000000000000000003788 172.0
DTH2_k127_7253567_3 nitrogen fixation - - - 0.00000000000000007373 88.0
DTH2_k127_7253567_4 lactoylglutathione lyase activity - - - 0.000000000004343 73.0
DTH2_k127_7253567_6 Universal stress protein family - - - 0.0000005783 57.0
DTH2_k127_7255214_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 300.0
DTH2_k127_7255214_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000312 244.0
DTH2_k127_7255214_2 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000000001152 215.0
DTH2_k127_7255214_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000002056 120.0
DTH2_k127_7255214_4 amino acid-binding ACT domain protein - - - 0.000000000000001431 83.0
DTH2_k127_727164_0 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 323.0
DTH2_k127_727164_1 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000002428 174.0
DTH2_k127_727164_2 COG1522 Transcriptional regulators K03718 - - 0.000000000000000000000005619 106.0
DTH2_k127_727164_3 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0001107 49.0
DTH2_k127_7342737_0 DNA polymerase type-B family K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 507.0
DTH2_k127_7342737_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001669 264.0
DTH2_k127_7342737_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000006812 214.0
DTH2_k127_7342737_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000002236 213.0
DTH2_k127_7342737_4 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000008042 154.0
DTH2_k127_7342737_5 - - - - 0.000000000000000000000000000002224 131.0
DTH2_k127_7360535_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.876e-248 785.0
DTH2_k127_7360535_1 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000002144 191.0
DTH2_k127_7372897_0 Sulfatase K01130 - 3.1.6.1 0.0 1230.0
DTH2_k127_7372897_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 356.0
DTH2_k127_7372897_2 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000001071 121.0
DTH2_k127_745109_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 597.0
DTH2_k127_745109_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 481.0
DTH2_k127_745109_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 345.0
DTH2_k127_745109_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 323.0
DTH2_k127_745109_4 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000819 133.0
DTH2_k127_745109_5 GHMP kinases N terminal domain K06982 - 2.7.1.169 0.000000000001257 71.0
DTH2_k127_7466638_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 414.0
DTH2_k127_7466638_1 DnaB-like helicase C terminal domain - - - 0.00000000000000000000000000000000000001121 153.0
DTH2_k127_7466638_2 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000001658 147.0
DTH2_k127_7489377_0 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000005465 138.0
DTH2_k127_7489377_1 Protein of unknown function (DUF835) - - - 0.00006446 52.0
DTH2_k127_7555510_0 COGs COG0145 N-methylhydantoinase A acetone carboxylase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 304.0
DTH2_k127_7593652_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 383.0
DTH2_k127_7593652_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 344.0
DTH2_k127_7593652_2 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 317.0
DTH2_k127_7593652_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005438 244.0
DTH2_k127_7593652_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000004658 126.0
DTH2_k127_7593652_5 - - - - 0.000000000000000000000001873 108.0
DTH2_k127_760655_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 406.0
DTH2_k127_760655_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000001174 152.0
DTH2_k127_760655_2 B12 binding domain - - - 0.00000000000000533 76.0
DTH2_k127_762763_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 422.0
DTH2_k127_762763_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 345.0
DTH2_k127_762763_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000008366 266.0
DTH2_k127_762763_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000006194 204.0
DTH2_k127_762763_4 4Fe-4S dicluster domain K00188 - 1.2.7.7 0.000000000000000000000000000002259 123.0
DTH2_k127_762763_5 SMART protein phosphatase 2C domain protein - - - 0.0002688 44.0
DTH2_k127_7691855_0 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000008265 219.0
DTH2_k127_7691855_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000178 179.0
DTH2_k127_7691855_2 Signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000444 135.0
DTH2_k127_7793782_0 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 385.0
DTH2_k127_7793782_1 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 370.0
DTH2_k127_7793782_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 304.0
DTH2_k127_7793782_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
DTH2_k127_7819623_0 AAA domain K01338 - 3.4.21.53 5.122e-195 620.0
DTH2_k127_7819623_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 555.0
DTH2_k127_7819623_10 electron transfer activity K05337 - - 0.000002515 53.0
DTH2_k127_7819623_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 518.0
DTH2_k127_7819623_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000002571 239.0
DTH2_k127_7819623_4 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000001731 224.0
DTH2_k127_7819623_5 - - - - 0.00000000000000000000000000000000000000000000000000000000212 208.0
DTH2_k127_7819623_6 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000000008393 117.0
DTH2_k127_7819623_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000002509 94.0
DTH2_k127_7819623_8 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000006435 80.0
DTH2_k127_7819623_9 Endodeoxyribonuclease RusA - - - 0.00000000000008652 78.0
DTH2_k127_7820045_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 291.0
DTH2_k127_7820045_1 - - - - 0.0000000000000000000000000000000000001082 148.0
DTH2_k127_7820045_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000003235 68.0
DTH2_k127_7820045_3 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.000000001998 61.0
DTH2_k127_7824519_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 469.0
DTH2_k127_7824519_1 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 434.0
DTH2_k127_7824519_2 Iron dependent K03709 - - 0.00000000000000000000000000000004969 131.0
DTH2_k127_7865945_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 456.0
DTH2_k127_7865945_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601,K08965 - 4.1.1.39,5.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 446.0
DTH2_k127_7866870_0 DEAD/H associated K03724 - - 0.0 1714.0
DTH2_k127_7866870_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000004959 111.0
DTH2_k127_7893950_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1101.0
DTH2_k127_7893950_1 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 7.097e-219 692.0
DTH2_k127_7893950_10 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000001418 102.0
DTH2_k127_7893950_11 - - - - 0.00000000000000002935 88.0
DTH2_k127_7893950_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.0000000004673 71.0
DTH2_k127_7893950_2 Carbamoyl-phosphate synthase L chain, ATP binding domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 426.0
DTH2_k127_7893950_3 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 301.0
DTH2_k127_7893950_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 298.0
DTH2_k127_7893950_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 276.0
DTH2_k127_7893950_6 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000008976 250.0
DTH2_k127_7893950_7 Universal stress protein family - - - 0.00000000000000000000000000000000000000003621 156.0
DTH2_k127_7893950_8 - - - - 0.00000000000000000000000000000001294 136.0
DTH2_k127_7893950_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000005941 115.0
DTH2_k127_7895601_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 525.0
DTH2_k127_7895601_1 component I K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 364.0
DTH2_k127_7895601_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000004204 252.0
DTH2_k127_7895601_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000008569 235.0
DTH2_k127_7895601_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000007119 207.0
DTH2_k127_7895601_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000003028 130.0
DTH2_k127_7895601_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000001466 122.0
DTH2_k127_7895601_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000006001 100.0
DTH2_k127_7895601_8 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000666 77.0
DTH2_k127_7895601_9 NADPH-dependent FMN reductase - - - 0.0000007778 53.0
DTH2_k127_791191_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001103 281.0
DTH2_k127_791191_1 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000003474 222.0
DTH2_k127_791191_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000001169 187.0
DTH2_k127_791191_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000002509 186.0
DTH2_k127_791191_4 Activator of Hsp90 ATPase - - - 0.000000000000000000005728 97.0
DTH2_k127_791191_5 TIGRFAM hydrogenase maturation protease - - - 0.000000000005767 72.0
DTH2_k127_791191_6 PAC2 family K06869 - - 0.00000000003788 67.0
DTH2_k127_7970272_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 318.0
DTH2_k127_7970272_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 290.0
DTH2_k127_7970272_2 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000002469 218.0
DTH2_k127_7970272_3 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000006307 144.0
DTH2_k127_7970272_4 ABC-2 family transporter protein K01992 - - 0.00000000000003016 79.0
DTH2_k127_7970272_5 TonB-dependent Receptor Plug - - - 0.0002944 52.0
DTH2_k127_8026594_0 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 332.0
DTH2_k127_8026594_1 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 312.0
DTH2_k127_8063612_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 6.093e-222 699.0
DTH2_k127_8063612_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 334.0
DTH2_k127_8063612_2 structural constituent of ribosome K02907 - - 0.00000000000000000000000000000000000000000000001026 181.0
DTH2_k127_8063612_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000008597 173.0
DTH2_k127_8063612_4 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002404 171.0
DTH2_k127_8063612_5 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000513 166.0
DTH2_k127_8063612_6 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000000002998 144.0
DTH2_k127_8073798_0 Aminotransferase class-III K00821,K05830 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 394.0
DTH2_k127_8073798_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 285.0
DTH2_k127_8073798_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000002799 228.0
DTH2_k127_8073798_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000001609 220.0
DTH2_k127_8118788_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 516.0
DTH2_k127_8118788_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 500.0
DTH2_k127_8118788_10 Thiamine-binding protein - - - 0.0000000000000000000002508 100.0
DTH2_k127_8118788_11 Belongs to the UPF0434 family - - - 0.0000000000001549 73.0
DTH2_k127_8118788_12 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000007732 52.0
DTH2_k127_8118788_13 membrane - - - 0.000001168 60.0
DTH2_k127_8118788_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 445.0
DTH2_k127_8118788_3 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 441.0
DTH2_k127_8118788_4 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 370.0
DTH2_k127_8118788_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 355.0
DTH2_k127_8118788_6 Oxidoreductase domain protein K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009603 274.0
DTH2_k127_8118788_7 - - - - 0.000000000000000000000000000000000000000000000000000007798 195.0
DTH2_k127_8118788_8 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000003739 116.0
DTH2_k127_8118788_9 - - - - 0.000000000000000000000000204 109.0
DTH2_k127_812111_0 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 349.0
DTH2_k127_812111_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 284.0
DTH2_k127_812111_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974,K18105 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4,6.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000003595 244.0
DTH2_k127_812111_3 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000002525 227.0
DTH2_k127_812111_4 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
DTH2_k127_812111_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000003198 125.0
DTH2_k127_812111_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025,K08723 - 3.1.3.5 0.0000000000000000000000006028 114.0
DTH2_k127_812111_7 - - - - 0.00000000000000000000002674 112.0
DTH2_k127_812111_8 Protein of unknown function DUF131 - - - 0.0000001551 58.0
DTH2_k127_8231293_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 310.0
DTH2_k127_8231293_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000006339 142.0
DTH2_k127_8249677_0 ABC-type multidrug transport system ATPase K01990,K16907 - - 0.0000000000000000000000000000000000000000000000000000000000000002602 229.0
DTH2_k127_8249677_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000004 218.0
DTH2_k127_8249677_2 - - - - 0.0002033 46.0
DTH2_k127_8253684_0 Alkyl sulfatase dimerisation - - - 4.864e-234 741.0
DTH2_k127_8253684_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 557.0
DTH2_k127_8253684_2 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 427.0
DTH2_k127_8253684_3 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000001239 163.0
DTH2_k127_8253684_4 Amidohydrolase K07045 - - 0.00000000000000000000005703 109.0
DTH2_k127_8253684_5 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.00000000000000002087 85.0
DTH2_k127_8290593_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 609.0
DTH2_k127_8290593_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 510.0
DTH2_k127_8290593_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 380.0
DTH2_k127_8290593_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 261.0
DTH2_k127_8290593_4 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000008714 230.0
DTH2_k127_8290593_5 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000003959 221.0
DTH2_k127_8290593_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000002233 188.0
DTH2_k127_8290593_7 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000000005325 175.0
DTH2_k127_8290593_8 PP-loop family K21947 - 2.8.1.15 0.000000000000000000000000000000003239 131.0
DTH2_k127_8290593_9 TIGRFAM transposase, IS605 OrfB family - - - 0.000000000000000002655 98.0
DTH2_k127_8294830_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 371.0
DTH2_k127_8294830_1 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 321.0
DTH2_k127_8294830_2 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000003657 223.0
DTH2_k127_8294830_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000001955 207.0
DTH2_k127_8294830_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000009151 138.0
DTH2_k127_8294830_5 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000005181 102.0
DTH2_k127_8294830_6 Ribosomal protein L37e K02922 - - 0.0000000000000000003322 87.0
DTH2_k127_8314811_0 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000006856 123.0
DTH2_k127_8314811_1 PFAM Phosphatidylglycerophosphatase A - - - 0.00000000000000000000000000001573 131.0
DTH2_k127_8314811_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000928 119.0
DTH2_k127_8314811_3 Adenosylcobinamide amidohydrolase - - - 0.000000000003266 78.0
DTH2_k127_8326020_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 485.0
DTH2_k127_8326020_1 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 324.0
DTH2_k127_8326020_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002905 206.0
DTH2_k127_8326020_3 - - - - 0.00001543 53.0
DTH2_k127_8333815_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 393.0
DTH2_k127_8333815_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002647 272.0
DTH2_k127_8333815_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000003867 173.0
DTH2_k127_8356293_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.617e-296 923.0
DTH2_k127_8356293_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006496 253.0
DTH2_k127_836901_0 KH domain K07041 - - 7.395e-266 833.0
DTH2_k127_836901_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 398.0
DTH2_k127_836901_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000009096 231.0
DTH2_k127_836901_3 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000006682 120.0
DTH2_k127_836901_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000004533 108.0
DTH2_k127_836901_5 formylmethanofuran dehydrogenase, subunit E - - - 0.0000000000000001869 85.0
DTH2_k127_836901_6 - - - - 0.0000000007846 66.0
DTH2_k127_8485448_0 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 293.0
DTH2_k127_8485448_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000000003126 219.0
DTH2_k127_8485448_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000001111 211.0
DTH2_k127_8485448_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000006803 191.0
DTH2_k127_8536811_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 439.0
DTH2_k127_8536811_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000005495 184.0
DTH2_k127_8536811_2 COG1403 Restriction endonuclease - - - 0.00000009747 57.0
DTH2_k127_8545938_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000005553 134.0
DTH2_k127_8545938_1 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000003905 121.0
DTH2_k127_8545938_2 protein conserved in archaea - - - 0.000000000000000000000000004366 117.0
DTH2_k127_8553486_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 361.0
DTH2_k127_8553486_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000004406 235.0
DTH2_k127_8553486_2 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000000000000000000000000000000000004832 189.0
DTH2_k127_8553486_3 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.0000000000000000002438 90.0
DTH2_k127_8553486_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000000000009116 89.0
DTH2_k127_8553486_5 PFAM Ribosomal LX protein K02944 - - 0.00002735 50.0
DTH2_k127_8556054_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 476.0
DTH2_k127_8556054_1 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.00000000000000000000000000000000000000000000000000000000000000000000000000001488 271.0
DTH2_k127_8556054_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000283 205.0
DTH2_k127_8572614_0 Isocitrate/isopropylmalate dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 582.0
DTH2_k127_8572614_1 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001256 271.0
DTH2_k127_8572614_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000001594 238.0
DTH2_k127_8572614_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000002565 123.0
DTH2_k127_8642768_0 Predicted membrane protein (DUF2085) - - - 0.0000000000000000004091 96.0
DTH2_k127_8642768_1 - - - - 0.000000000005006 71.0
DTH2_k127_8642768_2 Phospholipid methyltransferase - - - 0.000000000006141 74.0
DTH2_k127_8642768_3 Pathogenicity locus - - - 0.0000009868 53.0
DTH2_k127_8645594_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 485.0
DTH2_k127_8645594_1 ATPases associated with a variety of cellular activities K10112,K17240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
DTH2_k127_8645594_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 389.0
DTH2_k127_8645594_3 membrane - - - 0.000000000000000000415 93.0
DTH2_k127_8645594_4 phosphate transport regulator K07220 - - 0.00004157 53.0
DTH2_k127_8662151_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.185e-237 755.0
DTH2_k127_8662151_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 362.0
DTH2_k127_8662151_10 - - - - 0.00000001501 58.0
DTH2_k127_8662151_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000002433 170.0
DTH2_k127_8662151_3 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000002219 163.0
DTH2_k127_8662151_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000522 154.0
DTH2_k127_8662151_5 flavin reductase - - - 0.0000000000000000000000000000001249 131.0
DTH2_k127_8662151_6 - - - - 0.0000000000000000000000000001281 123.0
DTH2_k127_8662151_7 - - - - 0.00000000000000000536 91.0
DTH2_k127_8662151_8 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000197 86.0
DTH2_k127_8662151_9 Papain family cysteine protease - - - 0.00000000004014 74.0
DTH2_k127_876844_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 329.0
DTH2_k127_876844_1 cellular manganese ion homeostasis - - - 0.000000003678 66.0
DTH2_k127_876844_2 cellular manganese ion homeostasis - - - 0.0001485 52.0
DTH2_k127_8847135_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 449.0
DTH2_k127_8847135_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 372.0
DTH2_k127_8847135_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 343.0
DTH2_k127_8847135_3 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000003209 240.0
DTH2_k127_8847135_4 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000003893 149.0
DTH2_k127_8847135_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000271 66.0
DTH2_k127_8874928_0 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 422.0
DTH2_k127_8874928_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 390.0
DTH2_k127_8874928_2 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000002551 199.0
DTH2_k127_8874928_3 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000003355 205.0
DTH2_k127_8874928_4 - - - - 0.00000000000003779 76.0
DTH2_k127_8874928_5 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000003284 77.0
DTH2_k127_8874928_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00004313 48.0
DTH2_k127_8953320_0 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
DTH2_k127_8953320_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002827 265.0
DTH2_k127_8953320_2 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000528 210.0
DTH2_k127_8953320_3 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000004374 210.0
DTH2_k127_8953320_4 xylanase chitin deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000001212 152.0
DTH2_k127_8953320_5 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000000004051 145.0
DTH2_k127_8965955_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 467.0
DTH2_k127_8965955_1 Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde - - - 0.0000000000000000000000000000000000000843 154.0
DTH2_k127_8965955_2 FR47-like protein - - - 0.0000000000000002569 85.0
DTH2_k127_89738_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.163e-299 935.0
DTH2_k127_89738_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002046 281.0
DTH2_k127_89738_2 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000024 229.0
DTH2_k127_89738_3 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000009502 151.0
DTH2_k127_89738_4 - - - - 0.00000000000000000000000000003846 121.0
DTH2_k127_89738_5 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000006203 118.0
DTH2_k127_89738_6 PRC-barrel domain - - - 0.0000000000000000000000001235 108.0
DTH2_k127_89738_7 PFAM Amino acid-binding ACT - - - 0.000000000000009766 79.0
DTH2_k127_89738_8 Tetratricopeptide repeat - - - 0.0006046 45.0
DTH2_k127_9005559_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 598.0
DTH2_k127_9005559_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000005488 143.0
DTH2_k127_9005559_3 COG1522 Transcriptional regulators - - - 0.0003485 46.0
DTH2_k127_9005677_0 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0052592,GO:0055114 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000008327 236.0
DTH2_k127_9005677_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000005866 204.0
DTH2_k127_9005677_2 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000001356 186.0
DTH2_k127_9005677_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.000000000000000000000000000000003047 135.0
DTH2_k127_9028144_0 Hydantoinase/oxoprolinase N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 601.0
DTH2_k127_9028144_1 Uroporphyrinogen decarboxylase K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 431.0
DTH2_k127_9028144_10 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000206 160.0
DTH2_k127_9028144_11 Formyl transferase - - - 0.00000000000000000000000000000000001812 146.0
DTH2_k127_9028144_12 - - - - 0.0000000000000000000000000003104 116.0
DTH2_k127_9028144_2 Metallopeptidase family M24 K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 304.0
DTH2_k127_9028144_3 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 290.0
DTH2_k127_9028144_4 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002609 265.0
DTH2_k127_9028144_5 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003478 263.0
DTH2_k127_9028144_6 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004139 255.0
DTH2_k127_9028144_7 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000003349 184.0
DTH2_k127_9028144_8 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000005839 154.0
DTH2_k127_9028144_9 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000000000001768 148.0
DTH2_k127_9032682_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 332.0
DTH2_k127_9049670_0 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001851 247.0
DTH2_k127_9049670_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000001662 159.0
DTH2_k127_9049670_2 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000516 142.0
DTH2_k127_9053823_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 361.0
DTH2_k127_9053823_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002279 260.0
DTH2_k127_9053823_2 TPR repeat - - - 0.0000000000000000000004243 101.0
DTH2_k127_9094828_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 273.0
DTH2_k127_9094828_1 ATP synthase (C/AC39) subunit K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000002839 239.0
DTH2_k127_9094828_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000002603 109.0
DTH2_k127_9094828_3 F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K K02124 - - 0.00000000000000000004875 91.0
DTH2_k127_9108493_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 332.0
DTH2_k127_9108493_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 302.0
DTH2_k127_9108493_2 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.0000000000000000000000000000000000000000000001042 174.0
DTH2_k127_9108493_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000003398 88.0
DTH2_k127_9119505_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 410.0
DTH2_k127_9119505_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000001568 192.0
DTH2_k127_9119505_2 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000001315 145.0
DTH2_k127_9119505_3 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000008314 143.0
DTH2_k127_9119505_4 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000002846 106.0
DTH2_k127_9119505_5 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000001094 110.0
DTH2_k127_9119505_6 - K06039,K07092 - - 0.000000000000000000003298 99.0
DTH2_k127_9119505_7 protein involved in the oxidation of intracellular sulfur K07236 - - 0.000000000000000005158 88.0
DTH2_k127_9119505_8 DsrH like protein K07237 - - 0.0000000000179 68.0
DTH2_k127_9120676_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 413.0
DTH2_k127_9120676_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 347.0
DTH2_k127_9120676_10 Transcription factor Pcc1 K09741 - - 0.00000000001775 69.0
DTH2_k127_9120676_11 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.0000000001824 64.0
DTH2_k127_9120676_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 329.0
DTH2_k127_9120676_3 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 307.0
DTH2_k127_9120676_4 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 312.0
DTH2_k127_9120676_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 300.0
DTH2_k127_9120676_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003584 284.0
DTH2_k127_9120676_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.00000000000000000000000000003356 120.0
DTH2_k127_9120676_9 binds to the 23S rRNA K02921 - - 0.000000000000000000000000006593 111.0
DTH2_k127_9193168_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 472.0
DTH2_k127_9193168_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 439.0
DTH2_k127_9193168_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
DTH2_k127_9193168_3 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001029 248.0
DTH2_k127_9193168_4 OsmC-like protein - - - 0.0000000000000000000000000000000000007138 143.0
DTH2_k127_9193168_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000003626 129.0
DTH2_k127_9193168_6 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000000003454 106.0
DTH2_k127_9193168_7 cheY-homologous receiver domain K07668 - - 0.000000000000000000007748 106.0
DTH2_k127_9193168_8 Ribosomal_L40e K02927 - - 0.0000000000000003635 79.0
DTH2_k127_9196268_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 413.0
DTH2_k127_9196268_1 Fibronectin type 3 domain K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 325.0
DTH2_k127_9196268_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000012 276.0
DTH2_k127_9196268_3 PFAM Tetratricopeptide repeat - - - 0.0002417 50.0
DTH2_k127_9228082_0 PFAM SufBD protein K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 524.0
DTH2_k127_9228082_1 Restriction endonuclease - - - 0.0000000000000000000000000008741 117.0
DTH2_k127_9228082_2 PFAM ABC transporter K09013 - - 0.00000000000000000000000004961 107.0
DTH2_k127_9228082_3 transcriptional regulators - - - 0.00004244 52.0
DTH2_k127_9237941_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 334.0
DTH2_k127_9237941_1 PFAM GPR1 FUN34 yaaH family K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005597 266.0
DTH2_k127_9237941_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000006326 271.0
DTH2_k127_9237941_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000003303 75.0
DTH2_k127_9246941_0 Sulfatase K01130 - 3.1.6.1 0.0 1335.0
DTH2_k127_9246941_1 GMP synthase C terminal domain K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 468.0
DTH2_k127_9246941_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 376.0
DTH2_k127_9246941_3 PIN domain of ribonuclease K07060 GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904 - 0.00000000000000000005805 94.0
DTH2_k127_9343546_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000002048 236.0
DTH2_k127_9343546_1 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000003622 239.0
DTH2_k127_9343546_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000004746 186.0
DTH2_k127_9343546_3 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000003484 117.0
DTH2_k127_9343546_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000001669 115.0
DTH2_k127_9343546_5 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000005274 114.0
DTH2_k127_9343546_6 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0007 43.0
DTH2_k127_9401394_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 501.0
DTH2_k127_9401394_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 359.0
DTH2_k127_9401394_10 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.000000000000000000000004016 108.0
DTH2_k127_9401394_11 Putative TM nitroreductase - - - 0.00000000000000000005474 92.0
DTH2_k127_9401394_12 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000002141 57.0
DTH2_k127_9401394_13 - - - - 0.0000001793 57.0
DTH2_k127_9401394_2 PEP-utilising enzyme, mobile domain K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 305.0
DTH2_k127_9401394_3 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 296.0
DTH2_k127_9401394_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004268 291.0
DTH2_k127_9401394_5 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
DTH2_k127_9401394_6 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000003321 260.0
DTH2_k127_9401394_7 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000003032 169.0
DTH2_k127_9401394_8 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000004598 160.0
DTH2_k127_9401394_9 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000002716 139.0
DTH2_k127_9405593_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.2,1.4.1.3,1.4.1.4 4.217e-205 648.0
DTH2_k127_9405593_1 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 3.557e-200 636.0
DTH2_k127_9405593_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000003699 143.0
DTH2_k127_9405593_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000945 43.0
DTH2_k127_9435816_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 256.0
DTH2_k127_9435816_1 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000002335 229.0
DTH2_k127_9435816_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002686 206.0
DTH2_k127_9435816_3 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000009065 189.0
DTH2_k127_9435816_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001707 160.0
DTH2_k127_9435816_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000003433 151.0
DTH2_k127_9435816_6 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000746 94.0
DTH2_k127_9435816_7 Belongs to the PDCD5 family K06875 - - 0.00000000000000000003025 96.0
DTH2_k127_9435816_8 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.0000000000000002156 85.0
DTH2_k127_9435816_9 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000004387 71.0
DTH2_k127_9476520_0 Acyl-CoA synthetase (NDP forming) K09181 - - 1.744e-197 640.0
DTH2_k127_9476520_1 Protein of unknown function DUF72 - - - 0.00000000000000000004519 93.0
DTH2_k127_9476520_2 DRTGG domain protein K06873 - - 0.000000000448 68.0
DTH2_k127_9552338_0 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.000000000000000000000000000000000000000000000004553 180.0
DTH2_k127_9552338_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000002493 181.0
DTH2_k127_9589642_0 PFAM phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 397.0
DTH2_k127_9589642_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 351.0
DTH2_k127_9589642_2 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005387 286.0
DTH2_k127_9589642_3 PHP-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
DTH2_k127_9589642_4 PFAM Pyridoxamine 5'-phosphate oxidase-related K07005 - - 0.000000000000000000000000000000000007831 143.0
DTH2_k127_9589642_5 - - - - 0.0000005662 60.0
DTH2_k127_963169_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 589.0
DTH2_k127_963169_1 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 363.0
DTH2_k127_963169_2 Phosphomethylpyrimidine kinase K00941,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 331.0
DTH2_k127_963169_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 326.0
DTH2_k127_963169_4 COG0438 Glycosyltransferase K19002 - 2.4.1.337 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001613 291.0
DTH2_k127_963169_6 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000001544 147.0
DTH2_k127_963169_7 - - - - 0.0000000000000000000000004841 109.0
DTH2_k127_963169_8 Transcriptional regulator K03719 - - 0.0007303 48.0
DTH2_k127_9636687_0 Membrane - - - 0.0000000000000000000000000000000007771 140.0
DTH2_k127_9636687_1 PAS domain - - - 0.000000000000000000000001134 119.0
DTH2_k127_9636687_2 Sigma-54 interaction domain - - - 0.00000000000000000001364 106.0
DTH2_k127_9636687_3 Flavodoxin-like fold - - - 0.000000000006926 68.0
DTH2_k127_964296_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 406.0
DTH2_k127_964296_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000001898 215.0
DTH2_k127_964296_2 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000000000000000000000524 212.0
DTH2_k127_9702283_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000000000002628 228.0
DTH2_k127_9702283_1 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000003534 205.0
DTH2_k127_9702283_2 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002545 183.0
DTH2_k127_9702283_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000113 79.0
DTH2_k127_9710832_0 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005378 279.0
DTH2_k127_9710832_1 -acetyltransferase - - - 0.000000000000000000000000003587 115.0
DTH2_k127_9710832_2 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000002258 71.0
DTH2_k127_9710832_3 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00003529 49.0
DTH2_k127_9736015_0 PFAM Glycosyl transferase, group 1 K13668 - 2.4.1.346 0.00000000000000000002636 102.0
DTH2_k127_9736015_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000008541 96.0
DTH2_k127_9744205_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 451.0
DTH2_k127_9744205_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 383.0
DTH2_k127_9744205_10 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.000000000000001437 80.0
DTH2_k127_9744205_11 cell redox homeostasis - - - 0.00000000000005617 77.0
DTH2_k127_9744205_12 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000001903 61.0
DTH2_k127_9744205_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000002612 64.0
DTH2_k127_9744205_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000002739 66.0
DTH2_k127_9744205_15 - - - - 0.0002916 46.0
DTH2_k127_9744205_2 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337,K22163 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 318.0
DTH2_k127_9744205_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341,K22167 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 294.0
DTH2_k127_9744205_4 Belongs to the complex I 20 kDa subunit family K00331,K22159 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007209 278.0
DTH2_k127_9744205_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001728 279.0
DTH2_k127_9744205_6 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002758 235.0
DTH2_k127_9744205_7 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000003066 204.0
DTH2_k127_9744205_8 PFAM PQQ enzyme repeat - - - 0.00000000000000000000000000000001399 143.0
DTH2_k127_9744205_9 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340,K05576,K22166 - 1.5.98.3,1.6.5.3 0.0000000000000000000000001262 110.0
DTH2_k127_9781226_0 helicase superfamily c-terminal domain K10896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 456.0
DTH2_k127_9781226_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 392.0
DTH2_k127_9781226_2 Methanogenesis marker protein 8 - - - 0.00000000000000000000000000000000000000000003648 169.0
DTH2_k127_9781226_3 Iron-sulfur cluster assembly accessory protein K13628,K15724 - - 0.0000000000000000000000000000000001633 134.0
DTH2_k127_9781226_4 Acetyltransferase (GNAT) domain - - - 0.0000001242 59.0
DTH2_k127_9816289_0 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 334.0
DTH2_k127_9816289_1 - - - - 0.000000000000002064 80.0
DTH2_k127_9940178_0 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 317.0
DTH2_k127_9940178_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000001261 198.0
DTH2_k127_9940178_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000003206 195.0
DTH2_k127_9940178_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000006681 105.0
DTH2_k127_9940178_4 response to heat K03668 - - 0.00000000007249 67.0
DTH2_k127_9940178_5 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000007154 56.0