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Overview

ID MAG00777
Name DTH2_bin.43
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Xanthomonadales
Family SZUA-36
Genus SZUA-36
Species SZUA-36 sp041306925
Assembly information
Completeness (%) 62.35
Contamination (%) 0.52
GC content (%) 58.0
N50 (bp) 5,475
Genome size (bp) 2,075,019

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1980

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10006733_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 569.0
DTH2_k127_10006733_1 Proline racemase K12658 - 5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 496.0
DTH2_k127_10006733_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 395.0
DTH2_k127_10006733_3 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 335.0
DTH2_k127_10006733_4 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 322.0
DTH2_k127_10006733_5 FCD - - - 0.0000000000000000000000000000000000000007402 156.0
DTH2_k127_10006733_6 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000005608 150.0
DTH2_k127_10006733_7 Endoglucanase K01179 - 3.2.1.4 0.00000000000000000002058 106.0
DTH2_k127_10075180_0 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 512.0
DTH2_k127_10075180_1 Belongs to the arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 301.0
DTH2_k127_1007763_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007361 278.0
DTH2_k127_1007763_1 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000006023 147.0
DTH2_k127_1007763_2 Domain of unknown function (DUF4124) - - - 0.0000000001734 68.0
DTH2_k127_1007763_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000005492 49.0
DTH2_k127_10081876_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 5.274e-270 862.0
DTH2_k127_10081876_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.378e-210 661.0
DTH2_k127_10081876_2 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.0000000000006459 68.0
DTH2_k127_10082084_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 412.0
DTH2_k127_10082084_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 387.0
DTH2_k127_10082084_2 transporter, permease K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 375.0
DTH2_k127_10082084_3 Belongs to the ABC transporter superfamily K15583 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 371.0
DTH2_k127_10082084_4 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000002478 183.0
DTH2_k127_10082084_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000005198 90.0
DTH2_k127_10082084_6 - - - - 0.00006775 53.0
DTH2_k127_1014057_0 CoA-binding domain protein K09181 - - 0.0 1035.0
DTH2_k127_1014057_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 449.0
DTH2_k127_1014057_2 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 367.0
DTH2_k127_1014057_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
DTH2_k127_1014057_4 - - - - 0.00000000000002011 75.0
DTH2_k127_1140931_0 PFAM membrane bound O-acyl transferase MBOAT family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 555.0
DTH2_k127_1140931_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 330.0
DTH2_k127_1140931_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000001926 159.0
DTH2_k127_1147618_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004162 303.0
DTH2_k127_1147618_1 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000000000000000001036 184.0
DTH2_k127_1147618_2 surface antigen variable number repeat protein K07001 - - 0.0000000000000000002608 91.0
DTH2_k127_1254544_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 1.489e-254 809.0
DTH2_k127_1254544_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 322.0
DTH2_k127_1254544_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000003471 147.0
DTH2_k127_1254544_3 - - - - 0.0000000000000000000000000000000000005106 149.0
DTH2_k127_1264982_0 Peptidase family M3 K01392 - 3.4.24.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 583.0
DTH2_k127_1264982_1 Belongs to the arylamine N-acetyltransferase family K00675 GO:0003674,GO:0003824,GO:0004060,GO:0008080,GO:0008374,GO:0016407,GO:0016410,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0046990 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000007911 232.0
DTH2_k127_1304058_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 8.439e-294 912.0
DTH2_k127_1304058_1 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 1.699e-250 783.0
DTH2_k127_1304058_2 - - - - 0.0002582 46.0
DTH2_k127_1306935_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 492.0
DTH2_k127_1306935_1 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 337.0
DTH2_k127_1306935_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000009667 231.0
DTH2_k127_1306935_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000001255 185.0
DTH2_k127_1308386_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 8.31e-261 824.0
DTH2_k127_1308386_1 AMP-binding enzyme C-terminal domain K00666 - - 9.379e-243 761.0
DTH2_k127_1308386_2 ABC transporter transmembrane region K06147,K11085 - - 2.562e-211 672.0
DTH2_k127_1308386_3 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 431.0
DTH2_k127_1308386_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 419.0
DTH2_k127_1308386_5 KAP family P-loop domain K07497 - - 0.00007671 46.0
DTH2_k127_1313721_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 6.25e-200 640.0
DTH2_k127_1313721_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 308.0
DTH2_k127_1313721_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000001578 239.0
DTH2_k127_1313721_3 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000001233 207.0
DTH2_k127_1313721_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000001452 155.0
DTH2_k127_1313721_5 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.000000000000000000000000000000000008657 143.0
DTH2_k127_1344145_0 Cytochrome b/b6/petB - - - 2.022e-205 668.0
DTH2_k127_1344145_1 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 615.0
DTH2_k127_1344145_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009031 259.0
DTH2_k127_1344145_3 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006577 244.0
DTH2_k127_1344145_4 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000152 164.0
DTH2_k127_1344145_5 CBS domain - - - 0.0000000000000000000000000000000000000000002302 163.0
DTH2_k127_1344145_6 Nitrogen regulatory protein P-II - - - 0.000000000000000000000000000000000000001094 150.0
DTH2_k127_1344543_0 2-keto-4-pentenoate hydratase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 494.0
DTH2_k127_1344543_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 372.0
DTH2_k127_1344543_2 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.0000000000000000000000000000000000000000000000000001242 192.0
DTH2_k127_1344543_3 protein conserved in bacteria containing a divergent form of TPR repeats - - - 0.00000000000000000000000000000000000000000004892 169.0
DTH2_k127_1346129_0 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 507.0
DTH2_k127_1346129_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
DTH2_k127_1346129_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001799 269.0
DTH2_k127_1346129_3 Carboxypeptidase - - - 0.0001788 53.0
DTH2_k127_1354488_0 General secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 426.0
DTH2_k127_1354488_1 General secretion pathway protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 320.0
DTH2_k127_1354488_2 COG4970 Tfp pilus assembly protein FimT K02457 - - 0.00000000000000000000000000000000007544 139.0
DTH2_k127_1354488_3 General secretion pathway protein K02459 - - 0.000000000000000000000000000000001331 139.0
DTH2_k127_1354488_4 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000001255 133.0
DTH2_k127_1354488_5 Prokaryotic N-terminal methylation motif - - - 0.000000000001181 74.0
DTH2_k127_1355158_0 III protein, CoA-transferase family K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 464.0
DTH2_k127_1355158_1 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 440.0
DTH2_k127_1355158_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 379.0
DTH2_k127_1355158_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 383.0
DTH2_k127_1358127_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.199e-307 955.0
DTH2_k127_1358127_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 610.0
DTH2_k127_1358127_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 432.0
DTH2_k127_1361990_0 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 538.0
DTH2_k127_1361990_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 382.0
DTH2_k127_1361990_2 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 374.0
DTH2_k127_1361990_3 peptidyl-prolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.000000000008074 72.0
DTH2_k127_1378056_0 COG1228 Imidazolonepropionase and related amidohydrolases - - - 1.074e-280 882.0
DTH2_k127_1378056_1 Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE K07306 - 1.8.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 396.0
DTH2_k127_1378056_2 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.000000000000000000000000000000000000000000000000000000001641 202.0
DTH2_k127_1392767_0 Bacterial regulatory protein, Fis family K10912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 562.0
DTH2_k127_1392767_1 Histidine kinase K07716,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 513.0
DTH2_k127_1392767_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 469.0
DTH2_k127_1392767_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 363.0
DTH2_k127_1392767_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 319.0
DTH2_k127_1392767_5 response regulator receiver K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000001527 254.0
DTH2_k127_1392767_6 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000001725 77.0
DTH2_k127_1392767_7 eight transmembrane protein EpsH - - - 0.00000000624 64.0
DTH2_k127_1392767_8 Polysaccharide biosynthesis protein - - - 0.00001029 56.0
DTH2_k127_1392767_9 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.00002414 53.0
DTH2_k127_1419822_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 503.0
DTH2_k127_1419822_1 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 417.0
DTH2_k127_1419822_2 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 404.0
DTH2_k127_1419822_3 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000000007125 155.0
DTH2_k127_1427681_0 Protein synonym acyl-CoA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 475.0
DTH2_k127_1427681_1 IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000001365 264.0
DTH2_k127_1427681_2 Major Facilitator Superfamily - - - 0.0000002778 52.0
DTH2_k127_1450924_0 receptor K02014 - - 0.0 1015.0
DTH2_k127_1450924_1 Alpha-amylase domain K21575 - 3.2.1.135 9.421e-218 687.0
DTH2_k127_1450924_2 Tryptophan halogenase K14266 - 1.14.19.9 2.428e-215 679.0
DTH2_k127_1450924_3 COG0477 Permeases of the major facilitator superfamily K16211 - - 9.443e-204 645.0
DTH2_k127_1450924_4 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 399.0
DTH2_k127_1450924_5 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 357.0
DTH2_k127_1450924_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003268 252.0
DTH2_k127_1450924_7 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000002297 71.0
DTH2_k127_1464938_0 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000003529 231.0
DTH2_k127_1464938_1 PFAM Peptidyl-prolyl cis-trans isomerase, cyclophilin-type K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000562 171.0
DTH2_k127_1464938_2 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000001995 163.0
DTH2_k127_1464938_3 Methyltransferase - - - 0.0000000000000000000000000000000000003061 141.0
DTH2_k127_1479443_0 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 600.0
DTH2_k127_1479443_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 484.0
DTH2_k127_1479443_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000005278 187.0
DTH2_k127_1507149_0 Bacterial protein of unknown function (DUF885) - - - 5.24e-199 636.0
DTH2_k127_1507149_1 Transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 546.0
DTH2_k127_1507149_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03828 - - 0.00000000000000000000000000000000000000000000003856 174.0
DTH2_k127_1507149_3 Peptidase dimerisation domain - - - 0.000000000000000000000008097 103.0
DTH2_k127_1507149_4 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000005323 81.0
DTH2_k127_1507149_5 Putative adhesin - - - 0.0000001336 62.0
DTH2_k127_1517651_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 387.0
DTH2_k127_1517651_1 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
DTH2_k127_1517651_2 ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000004841 224.0
DTH2_k127_1517651_3 - - - - 0.0000000000000000000000000000000008375 136.0
DTH2_k127_1562791_0 Fumarase C C-terminus - - - 1.014e-234 736.0
DTH2_k127_1562791_1 Predicted Permease Membrane Region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 480.0
DTH2_k127_1562791_2 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 429.0
DTH2_k127_1562791_3 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 387.0
DTH2_k127_1562791_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000000000000001727 171.0
DTH2_k127_1573_0 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000001126 267.0
DTH2_k127_1573_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000002795 179.0
DTH2_k127_1573_2 2-phosphoglycerate kinase K05715 - - 0.000000000000000000000000000000000000000008749 177.0
DTH2_k127_1573_3 - - - - 0.00000000000000000000000000000000000000007279 155.0
DTH2_k127_1573_4 small membrane protein - - - 0.00000000002432 68.0
DTH2_k127_1608632_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 469.0
DTH2_k127_1608632_1 Acetyl-coenzyme A transporter 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002658 256.0
DTH2_k127_1608632_2 - - - - 0.00000000000000000000000000000000000000000000000004366 181.0
DTH2_k127_1608632_3 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000006438 180.0
DTH2_k127_1608632_4 Transcription factor zinc-finger - - - 0.0000000000000000000000000000002746 141.0
DTH2_k127_1608632_5 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.000000000000000000000004869 109.0
DTH2_k127_1626744_0 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 0.0 1062.0
DTH2_k127_1626744_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 395.0
DTH2_k127_1626744_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000003164 164.0
DTH2_k127_1626744_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000002442 135.0
DTH2_k127_164097_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 433.0
DTH2_k127_164097_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 308.0
DTH2_k127_164097_2 - - - - 0.00000000000000000000000000000000000000000000000000000008487 218.0
DTH2_k127_164948_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 574.0
DTH2_k127_164948_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 424.0
DTH2_k127_164948_2 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
DTH2_k127_164948_3 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000001406 182.0
DTH2_k127_164948_4 permeases K07091 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000817 96.0
DTH2_k127_164948_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.00000002959 63.0
DTH2_k127_1653181_0 Histidine kinase - - - 2.196e-222 718.0
DTH2_k127_1653181_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001048 237.0
DTH2_k127_165346_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 1.533e-220 708.0
DTH2_k127_165346_1 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000003249 116.0
DTH2_k127_165346_2 Tetratricopeptide repeat - - - 0.00000000000000000000004566 106.0
DTH2_k127_1675579_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 361.0
DTH2_k127_1675579_1 diol metabolic process K01724 - 4.2.1.96 0.00000000000000000000000000000001427 130.0
DTH2_k127_1675579_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000006071 136.0
DTH2_k127_1692022_0 PFAM Peptidase M1 membrane alanine aminopeptidase K01263 - 3.4.11.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 623.0
DTH2_k127_1692022_1 Clostripain family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002311 251.0
DTH2_k127_1692022_2 CHAT domain - - - 0.0000000000000000000000000002335 127.0
DTH2_k127_1741980_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1284.0
DTH2_k127_1741980_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 521.0
DTH2_k127_1741980_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000003627 146.0
DTH2_k127_1741980_3 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000000000000000000000000000486 143.0
DTH2_k127_1741980_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000002423 125.0
DTH2_k127_1768658_0 Cytochrome c554 and c-prime - - - 2.764e-214 685.0
DTH2_k127_1768658_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 344.0
DTH2_k127_1768658_2 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001039 266.0
DTH2_k127_1768658_3 Pfam Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000002255 181.0
DTH2_k127_1768658_4 response regulator - - - 0.00000000000000000000000000000000000000000000002445 177.0
DTH2_k127_1768658_5 Cytochrome c - - - 0.0000000000000000000000000000000002497 146.0
DTH2_k127_1768658_6 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.0003512 47.0
DTH2_k127_1807007_0 Domain of unknown function (DUF5117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 599.0
DTH2_k127_1807007_1 NADPH, quinone K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 352.0
DTH2_k127_1807007_2 Acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 307.0
DTH2_k127_1807007_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000004436 208.0
DTH2_k127_1832589_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000000000000000000000000000009251 166.0
DTH2_k127_1840791_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1246.0
DTH2_k127_1840791_1 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
DTH2_k127_1840791_2 Protein of unknown function (DUF489) K07153 - - 0.00000000000000002054 85.0
DTH2_k127_1840791_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000001952 71.0
DTH2_k127_185617_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564 - 2.843e-238 756.0
DTH2_k127_185617_1 Hydrogenase formation hypA family K04654 GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 574.0
DTH2_k127_185617_2 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 390.0
DTH2_k127_185617_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 339.0
DTH2_k127_185617_4 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000000000000002049 206.0
DTH2_k127_185617_5 PFAM HupH hydrogenase expression protein K03618 - - 0.0000000000000000000000000000000000000000541 157.0
DTH2_k127_185617_6 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000000001021 122.0
DTH2_k127_1899678_0 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 549.0
DTH2_k127_1899678_1 Response regulator receiver K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 432.0
DTH2_k127_1899678_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000007893 158.0
DTH2_k127_1899678_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000003652 130.0
DTH2_k127_1940699_0 Phosphate starvation protein PhoH K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 563.0
DTH2_k127_1940699_1 AI-2E family transporter K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 375.0
DTH2_k127_1940699_2 aromatic hydrocarbon degradation K06076 - - 0.000000000000004301 87.0
DTH2_k127_1949433_0 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.000000000000000000000000000000000000000000003833 172.0
DTH2_k127_1949433_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001895 145.0
DTH2_k127_1949433_2 - - - - 0.0000000000000000000000611 106.0
DTH2_k127_1949433_3 - - - - 0.000000000000000000001467 106.0
DTH2_k127_1970064_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1011.0
DTH2_k127_1970064_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.102e-297 923.0
DTH2_k127_1970064_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.061e-243 760.0
DTH2_k127_1970064_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 584.0
DTH2_k127_1970064_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 435.0
DTH2_k127_1970064_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000001435 196.0
DTH2_k127_1970064_6 - - - - 0.00000000000000000000000000000002119 134.0
DTH2_k127_1970064_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000137 127.0
DTH2_k127_1970064_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000004338 106.0
DTH2_k127_2044420_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 602.0
DTH2_k127_2044420_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 475.0
DTH2_k127_2044420_2 Belongs to the alpha-IPM synthase homocitrate synthase family K09011 - 2.3.1.182 0.000000000000000000000000000000000000000002719 158.0
DTH2_k127_2077383_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 408.0
DTH2_k127_2077383_1 abc transporter atp-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 320.0
DTH2_k127_2077383_2 antiporter K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 314.0
DTH2_k127_2077383_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000005914 188.0
DTH2_k127_2077383_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000009596 145.0
DTH2_k127_2077383_5 Belongs to the BolA IbaG family - - - 0.000000000000000000000002979 105.0
DTH2_k127_2077383_6 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.00000000000002974 80.0
DTH2_k127_2077383_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000000000001611 76.0
DTH2_k127_2085894_0 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 616.0
DTH2_k127_2085894_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 493.0
DTH2_k127_2085894_2 POT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 387.0
DTH2_k127_2085894_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002071 256.0
DTH2_k127_2085894_4 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000215 256.0
DTH2_k127_2085894_5 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000005159 186.0
DTH2_k127_2085894_6 YbaK proline--tRNA ligase associated domain protein K19055 GO:0002161,GO:0002196,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006417,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0045727,GO:0045903,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:2000112 - 0.000000000000000000000000000000000000000000001011 172.0
DTH2_k127_2085894_7 ligase activity - - - 0.000000000008741 69.0
DTH2_k127_2100144_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 505.0
DTH2_k127_2100144_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007631 277.0
DTH2_k127_2100144_2 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000002534 150.0
DTH2_k127_2100144_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000002728 141.0
DTH2_k127_2100144_4 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.000000000000000006324 86.0
DTH2_k127_2173898_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 7.021e-234 741.0
DTH2_k127_2173898_1 - - - - 0.00004901 49.0
DTH2_k127_2177365_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 1.47e-231 723.0
DTH2_k127_2177365_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 572.0
DTH2_k127_2177365_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 564.0
DTH2_k127_2177365_3 Magnesium chelatase, subunit ChlI K03974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 418.0
DTH2_k127_2177365_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000522 179.0
DTH2_k127_2177365_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000001644 174.0
DTH2_k127_2177365_6 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.000000000000000000000000000000000003375 139.0
DTH2_k127_2177365_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002664 126.0
DTH2_k127_2177365_8 Acyltransferase family - - - 0.0000000000000000000000002698 119.0
DTH2_k127_2177365_9 Mg2 and Co2 transporter CorB - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000007679 76.0
DTH2_k127_2184865_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 543.0
DTH2_k127_2184865_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 499.0
DTH2_k127_2184865_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 439.0
DTH2_k127_2206561_0 Putative phosphatase (DUF442) K17218 - 1.8.5.4 5.099e-215 681.0
DTH2_k127_2206561_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 545.0
DTH2_k127_2206561_2 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 458.0
DTH2_k127_2206561_3 Phenylacetate-CoA oxygenase K02609 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 397.0
DTH2_k127_2206561_4 Phenylacetate-CoA oxygenase, PaaI subunit K02611 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 345.0
DTH2_k127_2206561_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 312.0
DTH2_k127_2206561_6 metal-sulfur cluster biosynthetic enzyme K02612 GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000003208 200.0
DTH2_k127_2206561_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000003722 194.0
DTH2_k127_2206561_8 enzyme of phenylacetate metabolism K02610 GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000002544 157.0
DTH2_k127_2211971_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 374.0
DTH2_k127_2211971_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000003398 267.0
DTH2_k127_2211971_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000247 135.0
DTH2_k127_2211971_3 SMR domain protein - - - 0.000000000000000000000000476 111.0
DTH2_k127_2211971_4 Protein of unknown function (DUF3301) - - - 0.00000001588 63.0
DTH2_k127_2211971_5 Stringent starvation protein B K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.00000001832 56.0
DTH2_k127_2219945_0 Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate K00265 GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 1759.0
DTH2_k127_2219945_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 315.0
DTH2_k127_2219945_2 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000001041 145.0
DTH2_k127_231353_0 Phosphoglucomutase K01835 - 5.4.2.2 1.173e-248 779.0
DTH2_k127_231353_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016744,GO:0044424,GO:0044444,GO:0044464 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 408.0
DTH2_k127_231353_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 411.0
DTH2_k127_231353_3 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007298 250.0
DTH2_k127_231353_4 Domain of unknown function (DUF4156) - - - 0.000000001435 59.0
DTH2_k127_231353_5 CarD-like protein K07736 - - 0.000000006403 64.0
DTH2_k127_2341472_0 AcrB/AcrD/AcrF family - - - 0.0 1074.0
DTH2_k127_2346582_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1280.0
DTH2_k127_2346582_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000001116 113.0
DTH2_k127_2346582_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.00000000000000000002306 93.0
DTH2_k127_2346582_3 amine dehydrogenase activity K20276 - - 0.0006648 44.0
DTH2_k127_2375038_0 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 347.0
DTH2_k127_2375038_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000006551 246.0
DTH2_k127_2375038_2 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000002684 116.0
DTH2_k127_2375038_3 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000006138 68.0
DTH2_k127_2389120_0 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 289.0
DTH2_k127_2389120_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000004524 245.0
DTH2_k127_2389120_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 244.0
DTH2_k127_2389120_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000004022 222.0
DTH2_k127_2389120_4 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000265 201.0
DTH2_k127_2389120_5 salt-induced outer membrane protein K07283 - - 0.0000000000000000000000000000000000000000000000359 178.0
DTH2_k127_2389120_6 Ferredoxin - - - 0.00000000000000000000000000000000000000000000005544 171.0
DTH2_k127_2392481_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001679 241.0
DTH2_k127_2392481_1 - - - - 0.000000000000000000000000000005831 122.0
DTH2_k127_2448872_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.284e-310 971.0
DTH2_k127_2448872_1 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000007305 115.0
DTH2_k127_2467921_0 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 466.0
DTH2_k127_2467921_1 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 300.0
DTH2_k127_2467921_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005238 256.0
DTH2_k127_2467921_3 nUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000006289 216.0
DTH2_k127_2467921_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000001015 96.0
DTH2_k127_2499896_0 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 553.0
DTH2_k127_2499896_1 chitinase K03791 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005867 245.0
DTH2_k127_2521220_0 alanine symporter K03310 - - 3.866e-215 678.0
DTH2_k127_2521220_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 482.0
DTH2_k127_2521220_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000004795 170.0
DTH2_k127_2521220_3 - - - - 0.000001893 53.0
DTH2_k127_2641126_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.168e-194 619.0
DTH2_k127_2641126_1 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 460.0
DTH2_k127_2641126_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000004137 203.0
DTH2_k127_2674426_0 elongation factor G K02355 - - 1.916e-280 877.0
DTH2_k127_2674426_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 430.0
DTH2_k127_2674426_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 336.0
DTH2_k127_2674426_3 Belongs to the peptidase S51 family - - - 0.0000000000000000000000000000000000000000001384 170.0
DTH2_k127_2684918_0 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 371.0
DTH2_k127_2684918_1 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 363.0
DTH2_k127_2684918_2 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 352.0
DTH2_k127_2684918_3 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 317.0
DTH2_k127_2684918_4 Tetratricopeptide repeat - - - 0.000007846 57.0
DTH2_k127_2716621_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 546.0
DTH2_k127_2716621_1 Biopolymer K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000249 261.0
DTH2_k127_2716621_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000001345 134.0
DTH2_k127_2716621_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000001022 90.0
DTH2_k127_2762719_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.306e-256 801.0
DTH2_k127_2762719_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.067e-232 728.0
DTH2_k127_2762719_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 436.0
DTH2_k127_2762719_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000006053 199.0
DTH2_k127_2807466_0 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 364.0
DTH2_k127_2807466_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009427 280.0
DTH2_k127_281960_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 9.542e-281 868.0
DTH2_k127_281960_1 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 8.114e-273 856.0
DTH2_k127_281960_2 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 428.0
DTH2_k127_281960_3 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847,K01848 GO:0003674,GO:0003824,GO:0004494,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0019842,GO:0031419,GO:0036094,GO:0046906,GO:0048037,GO:0097159,GO:1901363 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 287.0
DTH2_k127_2837363_0 Proton-conducting membrane transporter - - - 4.241e-279 872.0
DTH2_k127_2837363_1 Proton-conducting membrane transporter K12141 - - 3.061e-224 703.0
DTH2_k127_2837363_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 499.0
DTH2_k127_2837363_3 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 441.0
DTH2_k127_2837363_4 carbamate kinase K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 405.0
DTH2_k127_2837363_5 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 306.0
DTH2_k127_2837363_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 261.0
DTH2_k127_2837363_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000001871 118.0
DTH2_k127_2887550_0 Belongs to the IlvD Edd family K01690,K22186,K22396 - 4.2.1.12,4.2.1.82 2.532e-234 739.0
DTH2_k127_2887550_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 9.335e-195 616.0
DTH2_k127_2887550_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004866 270.0
DTH2_k127_2887550_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000831 155.0
DTH2_k127_2902429_0 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 496.0
DTH2_k127_2902429_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 369.0
DTH2_k127_2902429_2 Cytochrome c, mono- and diheme variants - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 335.0
DTH2_k127_2902429_3 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000004924 190.0
DTH2_k127_2902429_4 Cytochrome C556 - - - 0.000000000000000002415 86.0
DTH2_k127_2902926_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.153e-258 802.0
DTH2_k127_2902926_1 cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 600.0
DTH2_k127_2902926_2 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 550.0
DTH2_k127_2902926_3 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 310.0
DTH2_k127_2902926_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 311.0
DTH2_k127_2902926_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000001623 134.0
DTH2_k127_2902926_6 protein conserved in bacteria K09926 - - 0.00000000002922 67.0
DTH2_k127_2902926_7 Cbb3-type cytochrome oxidase K00407 - - 0.0000002048 57.0
DTH2_k127_2902926_8 Cytochrome oxidase maturation protein - - - 0.0000003276 59.0
DTH2_k127_2908683_0 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 6.085e-217 682.0
DTH2_k127_2908683_1 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 496.0
DTH2_k127_2908683_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 384.0
DTH2_k127_2908683_3 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000005617 138.0
DTH2_k127_2908683_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000005079 128.0
DTH2_k127_2926848_0 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 406.0
DTH2_k127_2926848_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000009974 214.0
DTH2_k127_3000815_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 3.928e-226 711.0
DTH2_k127_3000815_1 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 7.989e-210 657.0
DTH2_k127_3000815_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 415.0
DTH2_k127_3000815_3 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 382.0
DTH2_k127_3000815_4 glutamate dehydrogenase K15371 - 1.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 332.0
DTH2_k127_3000815_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 301.0
DTH2_k127_3000815_6 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 302.0
DTH2_k127_3008670_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.935e-237 742.0
DTH2_k127_3008670_1 Sigma-54 interaction domain K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 372.0
DTH2_k127_3008670_2 Signal transduction histidine kinase, nitrogen specific K07708 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000002211 200.0
DTH2_k127_3008670_3 Domain of unknown function (DUF4124) - - - 0.000000000006591 74.0
DTH2_k127_3031734_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.539e-197 629.0
DTH2_k127_3031734_1 Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000152 280.0
DTH2_k127_3031734_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000005351 93.0
DTH2_k127_3036315_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 2.268e-237 747.0
DTH2_k127_3036315_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K03783,K03815,K19696 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006148,GO:0006149,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008617,GO:0009056,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009987,GO:0015949,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0022607,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0042454,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046094,GO:0046102,GO:0046115,GO:0046121,GO:0046122,GO:0046124,GO:0046128,GO:0046130,GO:0046483,GO:0046700,GO:0047724,GO:0047975,GO:0051259,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658,GO:1903227,GO:1903228 2.4.2.1,2.4.2.28,2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000001553 235.0
DTH2_k127_3036315_2 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.00000000000000000000000000000004047 128.0
DTH2_k127_30721_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 462.0
DTH2_k127_30721_1 DNA processing protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 356.0
DTH2_k127_30721_2 peptidoglycan-binding protein, lysm - - - 0.000000000000000000000000000000000000000000000000000000000000000000003329 250.0
DTH2_k127_30721_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000009993 226.0
DTH2_k127_30721_4 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000001574 195.0
DTH2_k127_30721_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000003179 192.0
DTH2_k127_3114467_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.665e-273 850.0
DTH2_k127_3114467_1 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 433.0
DTH2_k127_3114467_2 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 412.0
DTH2_k127_3114467_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 337.0
DTH2_k127_3114467_4 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.00000000000000000000000000000000000002637 150.0
DTH2_k127_3114467_5 SURF1-like protein K14998 - - 0.000000000000001657 81.0
DTH2_k127_3114467_6 Protein of unknown function (DUF2909) - - - 0.0000000000009076 70.0
DTH2_k127_3114467_7 Type II secretion system protein B K02451 - - 0.0000002311 61.0
DTH2_k127_3173920_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.404e-200 646.0
DTH2_k127_3173920_1 Protein conserved in bacteria K09978 - - 0.00000000000000001388 87.0
DTH2_k127_3173920_3 Protein involved in outer membrane biogenesis K09800 - - 0.000000000000001496 78.0
DTH2_k127_3202665_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.058e-254 794.0
DTH2_k127_3202665_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.113e-235 747.0
DTH2_k127_3224920_0 NADH ubiquinone oxidoreductase K00122 - 1.17.1.9 2.248e-243 765.0
DTH2_k127_3224920_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 9.287e-228 714.0
DTH2_k127_3224920_2 NADH ubiquinone oxidoreductase K18006 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 369.0
DTH2_k127_3224920_3 PFAM NADH Ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 305.0
DTH2_k127_3224920_4 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 304.0
DTH2_k127_3224920_5 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000962 162.0
DTH2_k127_3224920_6 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000007927 156.0
DTH2_k127_3224920_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000001092 58.0
DTH2_k127_3234709_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 340.0
DTH2_k127_3234709_1 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.000000000000000000000000000000000000000000003443 167.0
DTH2_k127_3252842_0 FMN-dependent dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 411.0
DTH2_k127_3252842_1 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 393.0
DTH2_k127_3252842_2 Dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 404.0
DTH2_k127_3252842_3 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 377.0
DTH2_k127_3252842_4 Acyl-CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 341.0
DTH2_k127_3252842_5 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000406 240.0
DTH2_k127_3252842_6 - - - - 0.000001692 57.0
DTH2_k127_3253850_0 Macrocin-O-methyltransferase (TylF) K05303 - - 0.0000000000000000000000000000000000000000000000000000000006083 212.0
DTH2_k127_3253850_1 hydrolase activity, acting on ester bonds K07017 - - 0.00000000000000000000000000000000000000000000000000005468 198.0
DTH2_k127_3253850_2 Protein of unknown function, DUF547 - - - 0.0000000000000000000000001747 112.0
DTH2_k127_3318251_0 Isocitrate lyase K01637 - 4.1.3.1 3.515e-289 894.0
DTH2_k127_3318251_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 593.0
DTH2_k127_3318251_2 Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 405.0
DTH2_k127_3318251_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 368.0
DTH2_k127_3332082_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 492.0
DTH2_k127_3332082_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 375.0
DTH2_k127_3332082_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000004945 223.0
DTH2_k127_3332082_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000151 188.0
DTH2_k127_3332082_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000004017 169.0
DTH2_k127_3332082_5 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000309 94.0
DTH2_k127_3332082_6 - - - - 0.000000000000001428 84.0
DTH2_k127_3332082_7 - - - - 0.000000000000003558 78.0
DTH2_k127_3341566_0 G COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 2.829e-203 643.0
DTH2_k127_3341566_1 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 361.0
DTH2_k127_3341566_2 PFAM response regulator receiver K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 312.0
DTH2_k127_3341566_3 TonB dependent receptor K02014 - - 0.000000000000000000000000001804 116.0
DTH2_k127_3347973_0 Cytochrome C biogenesis K02198 - - 4.755e-233 738.0
DTH2_k127_3347973_1 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 434.0
DTH2_k127_3347973_10 S1 P1 nuclease K05986 - 3.1.30.1 0.000000000000000000000000000000001261 140.0
DTH2_k127_3347973_11 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000002172 132.0
DTH2_k127_3347973_12 Recombinase - - - 0.0001024 46.0
DTH2_k127_3347973_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
DTH2_k127_3347973_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 302.0
DTH2_k127_3347973_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000019 256.0
DTH2_k127_3347973_5 S-adenosylmethionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000179 212.0
DTH2_k127_3347973_6 Thiol disulfide interchange protein K02199 - - 0.000000000000000000000000000000000000000000000000000215 193.0
DTH2_k127_3347973_7 Cytochrome C biogenesis K02200 - - 0.00000000000000000000000000000000000000000000015 182.0
DTH2_k127_3347973_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000001266 163.0
DTH2_k127_3347973_9 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000003298 162.0
DTH2_k127_3348572_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 481.0
DTH2_k127_3348572_1 drug resistance transporter Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 342.0
DTH2_k127_3349899_0 PFAM Radical SAM K19810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 300.0
DTH2_k127_3349899_1 OmpW family K07275 - - 0.0000000000000000000000000000000000000000000000000000008614 198.0
DTH2_k127_3349899_2 Belongs to the GcvT family K00605 - 2.1.2.10 0.00000000006239 63.0
DTH2_k127_3396979_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 1.748e-268 846.0
DTH2_k127_3396979_1 PFAM phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 374.0
DTH2_k127_3396979_2 conserved secreted or membrane protein precursor - - - 0.00000000000000000000000000000000000000000000000000000000000000000007343 238.0
DTH2_k127_3396979_3 Peptidase propeptide and YPEB domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008651 237.0
DTH2_k127_3396979_4 FMN_bind - - - 0.000000000000000000000000000000000000000003053 160.0
DTH2_k127_3396979_5 PepSY-associated TM region - - - 0.0000000000000000000000000000000002204 142.0
DTH2_k127_3396979_6 Universal stress protein family - - - 0.000000000000000000000002273 111.0
DTH2_k127_3396979_7 cAMP biosynthetic process - - - 0.0000001536 53.0
DTH2_k127_342623_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 329.0
DTH2_k127_342623_1 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000000000000000000007209 220.0
DTH2_k127_342623_2 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 GO:0000104,GO:0001539,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006996,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016635,GO:0022607,GO:0030030,GO:0030031,GO:0032991,GO:0040011,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048870,GO:0051179,GO:0051674,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0097588,GO:0098796,GO:0098797,GO:0098803 - 0.0000000000000000444 88.0
DTH2_k127_342623_3 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016627,GO:0016635,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 - 0.000000000004669 75.0
DTH2_k127_3462227_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 608.0
DTH2_k127_3462227_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 0.0000000000000000000000000000000000000000000000000000008208 200.0
DTH2_k127_3462227_2 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000003951 170.0
DTH2_k127_3462227_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000001001 109.0
DTH2_k127_3462227_4 Domain of unknown function (DUF4252) - - - 0.00000000000000002399 87.0
DTH2_k127_3462227_5 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000002635 77.0
DTH2_k127_3462227_6 Acyltransferase family - GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000001116 53.0
DTH2_k127_3513030_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.535e-305 962.0
DTH2_k127_3513030_1 dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000003284 229.0
DTH2_k127_3513030_2 - - - - 0.00000000000000000000000000004587 127.0
DTH2_k127_3513030_3 - - - - 0.0001025 49.0
DTH2_k127_3583684_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 7.815e-211 664.0
DTH2_k127_3583684_1 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000000000000000163 189.0
DTH2_k127_3583684_2 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000007483 178.0
DTH2_k127_3583684_3 membrane - - - 0.00000000000000000002405 91.0
DTH2_k127_3583684_4 Protein required for attachment to host cells - - - 0.000000000000000009059 89.0
DTH2_k127_3583684_5 NAD(P)H-binding - - - 0.000000000205 67.0
DTH2_k127_360173_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 415.0
DTH2_k127_360173_1 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000002407 232.0
DTH2_k127_360173_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000002585 205.0
DTH2_k127_3609673_0 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 1.102e-277 868.0
DTH2_k127_3609673_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 6.83e-238 739.0
DTH2_k127_3609673_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001626 253.0
DTH2_k127_3609673_11 NADH dehydrogenase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001179 242.0
DTH2_k127_3609673_12 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000003122 226.0
DTH2_k127_3609673_13 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000004701 163.0
DTH2_k127_3609673_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000007066 158.0
DTH2_k127_3609673_15 - - - - 0.000000007774 56.0
DTH2_k127_3609673_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 8.778e-230 716.0
DTH2_k127_3609673_3 NADH-quinone oxidoreductase K00336 - 1.6.5.3 3.033e-224 719.0
DTH2_k127_3609673_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.083e-222 700.0
DTH2_k127_3609673_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 492.0
DTH2_k127_3609673_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 468.0
DTH2_k127_3609673_7 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 304.0
DTH2_k127_3609673_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 306.0
DTH2_k127_3609673_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001248 259.0
DTH2_k127_3629370_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 289.0
DTH2_k127_3629370_1 overlaps another CDS with the same product name K07112 - - 0.00000000000000000000000000000000000000000000000000000000004098 209.0
DTH2_k127_3629370_2 - K07112 - - 0.00000000000000000000000000000000000000000000000000003622 192.0
DTH2_k127_3629370_3 - K09004 - - 0.0000000000000000000000000000007303 124.0
DTH2_k127_365257_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 366.0
DTH2_k127_365257_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 287.0
DTH2_k127_365257_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000002835 195.0
DTH2_k127_365257_3 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000006377 122.0
DTH2_k127_365257_4 IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.000000000000000000000000000007761 123.0
DTH2_k127_3676840_0 Belongs to the proline racemase family - GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0050346 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 480.0
DTH2_k127_3676840_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 304.0
DTH2_k127_3695469_0 catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1500.0
DTH2_k127_3695469_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 502.0
DTH2_k127_3695469_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
DTH2_k127_3695469_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 372.0
DTH2_k127_3695469_4 helix_turn_helix ASNC type K05800 - - 0.0000000000000000000000000000000000000000000000000000000001825 207.0
DTH2_k127_3726658_0 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 550.0
DTH2_k127_3726658_1 TIGRFAM glycosyl transferase, WecB TagA CpsF family K05946,K13660 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 535.0
DTH2_k127_3726658_2 Acyltransferase - - - 0.0000000789 55.0
DTH2_k127_3726658_3 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00005141 54.0
DTH2_k127_3777466_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.351e-291 906.0
DTH2_k127_3777466_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 432.0
DTH2_k127_3777466_10 Positive regulator of sigma(E), RseC/MucC - - - 0.000009185 54.0
DTH2_k127_3777466_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 411.0
DTH2_k127_3777466_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 321.0
DTH2_k127_3777466_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
DTH2_k127_3777466_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
DTH2_k127_3777466_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000007125 236.0
DTH2_k127_3777466_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000001518 202.0
DTH2_k127_3777466_8 MucB/RseB C-terminal domain K03598 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - 0.0000000000000000000000000000000000000007817 158.0
DTH2_k127_3777466_9 Domain of unknown function (DUF4845) - - - 0.0000000000000000000000002639 112.0
DTH2_k127_3779831_0 Acetolactate synthase K01652 - 2.2.1.6 8.12e-279 869.0
DTH2_k127_3779831_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 407.0
DTH2_k127_3779831_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 369.0
DTH2_k127_3779831_3 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000001002 196.0
DTH2_k127_3795377_0 orn lys arg decarboxylase K01583 - 4.1.1.19 0.0 1198.0
DTH2_k127_3795377_1 Predicted Permease Membrane Region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 465.0
DTH2_k127_3815411_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 439.0
DTH2_k127_3833888_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1237.0
DTH2_k127_3833888_1 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 3.239e-251 793.0
DTH2_k127_3833888_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001127 259.0
DTH2_k127_3833888_3 PA domain - - - 0.000000000000000000000000000000000000000000352 160.0
DTH2_k127_3842356_0 Aldehyde dehydrogenase K02618 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.2.1.91,3.3.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 484.0
DTH2_k127_3842356_1 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 459.0
DTH2_k127_3842356_2 Phenylacetic acid degradation protein PaaY K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004513 263.0
DTH2_k127_3842356_3 enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
DTH2_k127_3860518_0 Sodium:neurotransmitter symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 546.0
DTH2_k127_3860518_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 450.0
DTH2_k127_3860518_2 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 279.0
DTH2_k127_3860518_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000004384 217.0
DTH2_k127_3860518_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001089 234.0
DTH2_k127_3860518_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000007369 198.0
DTH2_k127_3860518_6 cAMP biosynthetic process - - - 0.00000000000000001223 98.0
DTH2_k127_3860518_7 - - - - 0.00000000000000001276 93.0
DTH2_k127_3876955_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 374.0
DTH2_k127_3876955_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 333.0
DTH2_k127_3876955_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 315.0
DTH2_k127_3876955_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007717 258.0
DTH2_k127_3876955_4 Protein of unknown function (DUF1456) - - - 0.000000000000000000000000000000000000000000000000000000000000003556 222.0
DTH2_k127_3876955_5 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000006445 153.0
DTH2_k127_3876955_6 S4 domain K14761 - - 0.0000000000000000000021 96.0
DTH2_k127_3876955_7 ATP synthase, subunit I K02116 GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000906 49.0
DTH2_k127_387905_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 497.0
DTH2_k127_387905_1 cystathionine K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 466.0
DTH2_k127_387905_2 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 310.0
DTH2_k127_387905_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000008026 166.0
DTH2_k127_3890973_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 3.769e-198 625.0
DTH2_k127_3890973_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 526.0
DTH2_k127_3890973_2 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 519.0
DTH2_k127_3890973_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000001769 218.0
DTH2_k127_3890973_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000002402 180.0
DTH2_k127_3890973_5 LssY C-terminus - - - 0.000000000000009408 81.0
DTH2_k127_3890973_6 - - - - 0.0000001569 59.0
DTH2_k127_3906048_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 461.0
DTH2_k127_3906048_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 419.0
DTH2_k127_3906048_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000001063 100.0
DTH2_k127_3918987_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.985e-260 810.0
DTH2_k127_3918987_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 484.0
DTH2_k127_3918987_2 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 372.0
DTH2_k127_3918987_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 359.0
DTH2_k127_3918987_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000002797 156.0
DTH2_k127_3918987_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000003772 155.0
DTH2_k127_3918987_6 Ion channel - - - 0.0000000000000000000000000001054 121.0
DTH2_k127_3918987_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000002069 117.0
DTH2_k127_3949788_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 5.115e-248 783.0
DTH2_k127_3949788_1 General secretion pathway protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 1.059e-195 624.0
DTH2_k127_3949788_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.00000000000000000000000008603 107.0
DTH2_k127_3949788_3 - - - - 0.000000000000000003903 94.0
DTH2_k127_3983405_0 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 453.0
DTH2_k127_3983405_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 359.0
DTH2_k127_3983405_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 299.0
DTH2_k127_3987505_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.182e-267 827.0
DTH2_k127_3987505_1 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 446.0
DTH2_k127_3987505_10 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000001268 103.0
DTH2_k127_3987505_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000008316 107.0
DTH2_k127_3987505_2 Fructose-1-6-bisphosphatase, N-terminal domain K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 374.0
DTH2_k127_3987505_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002417 290.0
DTH2_k127_3987505_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000006065 222.0
DTH2_k127_3987505_5 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000001244 194.0
DTH2_k127_3987505_6 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000005792 197.0
DTH2_k127_3987505_7 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000003518 195.0
DTH2_k127_3987505_8 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000002346 186.0
DTH2_k127_3987505_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000002052 143.0
DTH2_k127_3988261_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.704e-291 905.0
DTH2_k127_3988261_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 407.0
DTH2_k127_3988261_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000001372 163.0
DTH2_k127_3988261_3 Protein of unknown function (DUF2608) - - - 0.0000000000000000000000000005744 126.0
DTH2_k127_4013278_0 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 530.0
DTH2_k127_4013278_1 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002653 301.0
DTH2_k127_4013278_2 Glycosyl transferase, family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000005927 229.0
DTH2_k127_4013278_3 Polysaccharide biosynthesis/export protein - - - 0.0000000000000000000000000000000000000000000001486 175.0
DTH2_k127_4013278_4 - - - - 0.00000000000000000000000000000000000004114 159.0
DTH2_k127_4013278_5 O-Antigen ligase - - - 0.0000000000000000000000000000000000001529 159.0
DTH2_k127_4013278_6 - - - - 0.00000000000000000000000000000000009157 153.0
DTH2_k127_4015701_0 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 592.0
DTH2_k127_4015701_1 PFAM aminotransferase class I and II K00813,K00832 - 2.6.1.1,2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 437.0
DTH2_k127_4015701_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 308.0
DTH2_k127_4015701_3 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000003848 254.0
DTH2_k127_4015701_4 mandelate racemase muconate lactonizing K01776,K02549,K19802 - 4.2.1.113,5.1.1.20,5.1.1.3 0.000000000000000000000000000000001326 131.0
DTH2_k127_4015701_5 Protein of unknown function - - - 0.000000000000000005461 97.0
DTH2_k127_4020762_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1146.0
DTH2_k127_4020762_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 519.0
DTH2_k127_4020762_2 Aldolase K01620 - 4.1.2.48 0.00000000003825 64.0
DTH2_k127_4041968_0 ATPase (AAA K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 445.0
DTH2_k127_4041968_1 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 359.0
DTH2_k127_4041968_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002384 240.0
DTH2_k127_4041968_3 Domain of unknown function (DUF4381) - - - 0.00000000000000000000001601 106.0
DTH2_k127_4041968_4 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0005538 45.0
DTH2_k127_4043988_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 422.0
DTH2_k127_4043988_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 332.0
DTH2_k127_4043988_2 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008388 265.0
DTH2_k127_4043988_3 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008391 263.0
DTH2_k127_4043988_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000007796 174.0
DTH2_k127_4043988_5 MAPEG family - - - 0.00000000000000000000000000001227 125.0
DTH2_k127_4043988_6 - - - - 0.0000005263 51.0
DTH2_k127_4044040_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 421.0
DTH2_k127_4044040_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 304.0
DTH2_k127_4044040_2 Protein of unknown function (DUF3450) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004551 238.0
DTH2_k127_4044040_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000108 210.0
DTH2_k127_4044040_4 COG0811 Biopolymer transport proteins K03561 - - 0.000000000000000000000000000000000000000000000000000001486 197.0
DTH2_k127_4044040_5 biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000000000000002115 190.0
DTH2_k127_4044040_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00009747 47.0
DTH2_k127_4057384_0 Male sterility protein - - - 2.061e-286 893.0
DTH2_k127_4057384_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 603.0
DTH2_k127_4057384_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 306.0
DTH2_k127_4057384_3 Acyl CoA binding protein - - - 0.00000000000000000000000000000005088 128.0
DTH2_k127_4057384_4 6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000004521 100.0
DTH2_k127_4057384_5 Bacterial transcriptional repressor - - - 0.0000000000000000009603 87.0
DTH2_k127_4059088_0 MTH538 TIR-like domain (DUF1863) K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003965 287.0
DTH2_k127_4059088_1 PFAM PEBP family protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 252.0
DTH2_k127_4059088_2 Deoxynucleoside kinase - - - 0.0000000000000000000006605 104.0
DTH2_k127_4059088_3 deoxynucleoside kinase - - - 0.000000000000008384 84.0
DTH2_k127_4059088_4 methyltransferase activity K21310 - 2.1.1.334 0.0000000000001285 77.0
DTH2_k127_407544_0 formate dehydrogenase K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 552.0
DTH2_k127_407544_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001069 280.0
DTH2_k127_407544_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 0.00000000000000000000000000000000181 138.0
DTH2_k127_407544_3 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.00000000000000005406 82.0
DTH2_k127_407544_4 formate dehydrogenase K00126 - 1.17.1.9 0.00000223 53.0
DTH2_k127_4076507_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 303.0
DTH2_k127_4076507_1 - - - - 0.000000000000000000000000000000000000000000008663 179.0
DTH2_k127_4076507_2 alpha/beta hydrolase fold - - - 0.0000000000000000002264 88.0
DTH2_k127_4090272_0 RnfC Barrel sandwich hybrid domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 437.0
DTH2_k127_4090272_1 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 331.0
DTH2_k127_4090272_2 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000005297 233.0
DTH2_k127_4090272_3 Part of a membrane complex involved in electron transport - - - 0.000000000000000000000000000000002044 143.0
DTH2_k127_4090272_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000004217 99.0
DTH2_k127_4090272_5 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000001959 78.0
DTH2_k127_4123417_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 8.735e-303 949.0
DTH2_k127_4123417_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 599.0
DTH2_k127_4123417_2 Transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 565.0
DTH2_k127_4123417_3 Sulfotransferase family - - - 0.0000000000000000000003416 99.0
DTH2_k127_4123417_4 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000002853 95.0
DTH2_k127_4138276_0 Methylmalonyl-CoA mutase - - - 2.384e-248 777.0
DTH2_k127_4138276_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 396.0
DTH2_k127_4138276_2 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 351.0
DTH2_k127_4138276_3 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000007836 240.0
DTH2_k127_4138276_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000009065 189.0
DTH2_k127_4138276_5 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000009747 165.0
DTH2_k127_4155558_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 535.0
DTH2_k127_4155558_1 TIGRFAM ABC exporter ATP-binding subunit, DevA family K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 415.0
DTH2_k127_4155558_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004202 255.0
DTH2_k127_4155558_3 Transposase - - - 0.00000000000000000000000003263 108.0
DTH2_k127_4157454_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001576 282.0
DTH2_k127_4157454_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K18143 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002032 285.0
DTH2_k127_4157454_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000002815 168.0
DTH2_k127_4163760_0 dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 605.0
DTH2_k127_4163760_1 aspartyl protease K06985 - - 0.000000000000000000000000001928 117.0
DTH2_k127_4175755_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 566.0
DTH2_k127_4175755_1 BT1 family K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 545.0
DTH2_k127_4175755_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 467.0
DTH2_k127_4175755_3 deacetylase K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 407.0
DTH2_k127_4175755_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 314.0
DTH2_k127_4175755_5 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 316.0
DTH2_k127_4175755_6 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
DTH2_k127_4175755_7 N-acetylglucosamine kinase activity K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.000000000000000000000000000000000000000000000001244 186.0
DTH2_k127_4197311_0 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626,K00632,K02615 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016740,GO:0016746,GO:0016747,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0033554,GO:0033812,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 599.0
DTH2_k127_4197311_1 Phenylacetate-CoA oxygenase K02609 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 0.00000000000000000000000000000000000000000000000000000002535 198.0
DTH2_k127_4197311_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000001634 127.0
DTH2_k127_4197311_3 COG1024 Enoyl-CoA hydratase carnithine racemase K15866 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 0.00000000000000000000000000001736 119.0
DTH2_k127_4197311_4 maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.00000000000000000007824 95.0
DTH2_k127_4197311_5 4Fe-4S dicluster domain - - - 0.000001603 56.0
DTH2_k127_420110_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 2.072e-219 714.0
DTH2_k127_420110_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002506 267.0
DTH2_k127_420110_2 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00127,K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000004914 202.0
DTH2_k127_420110_3 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000008727 108.0
DTH2_k127_4201414_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.79e-201 643.0
DTH2_k127_4201414_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
DTH2_k127_4201414_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000003106 231.0
DTH2_k127_4201414_3 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000001295 140.0
DTH2_k127_420301_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 473.0
DTH2_k127_4260497_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 345.0
DTH2_k127_4260497_1 helix_turn_helix, Lux Regulon K07684 - - 0.000000000000000000000000000000000000000000000000000000000000005695 223.0
DTH2_k127_4260497_2 N-terminal 7TM region of histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000004208 230.0
DTH2_k127_4311931_0 Glycosyl-hydrolase 97 C-terminal, oligomerisation K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 481.0
DTH2_k127_4311931_1 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 399.0
DTH2_k127_4311931_2 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 367.0
DTH2_k127_4311931_3 Belongs to the bacterial glucokinase family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001409 241.0
DTH2_k127_4347218_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
DTH2_k127_4347218_1 protein conserved in bacteria K09938 - - 0.0000000000000000000000000005006 126.0
DTH2_k127_4347218_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000003047 87.0
DTH2_k127_437627_0 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 405.0
DTH2_k127_437627_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 390.0
DTH2_k127_437627_2 DoxX K15977 - - 0.00000000000000000000000000000000000000000000002413 173.0
DTH2_k127_4444704_0 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
DTH2_k127_4444704_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000003376 170.0
DTH2_k127_4444704_2 Type II transport protein GspH K08084 - - 0.00000000000000000000005491 105.0
DTH2_k127_4444704_3 - - - - 0.0002429 45.0
DTH2_k127_4456925_0 PFAM peptidase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 499.0
DTH2_k127_4456925_1 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 350.0
DTH2_k127_4456925_2 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000003672 138.0
DTH2_k127_4469061_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 354.0
DTH2_k127_4469061_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000006681 148.0
DTH2_k127_4477162_0 Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 334.0
DTH2_k127_4477162_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000006306 230.0
DTH2_k127_4477162_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000005023 156.0
DTH2_k127_4477162_3 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000009416 108.0
DTH2_k127_4477162_4 - - - - 0.0000000000000001019 85.0
DTH2_k127_4530026_0 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 606.0
DTH2_k127_4530026_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 500.0
DTH2_k127_4530026_2 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 492.0
DTH2_k127_4530026_3 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 370.0
DTH2_k127_4530026_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 294.0
DTH2_k127_4530026_5 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000000000000000000000000001283 217.0
DTH2_k127_4530026_6 Class III cytochrome C family - - - 0.000002413 56.0
DTH2_k127_4530026_7 amine dehydrogenase activity K21449 - - 0.00005102 52.0
DTH2_k127_4559557_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 449.0
DTH2_k127_4559557_1 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 436.0
DTH2_k127_4559557_2 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 301.0
DTH2_k127_4559557_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000001946 192.0
DTH2_k127_4596593_0 Sortilin, neurotensin receptor 3, - - - 0.0 1365.0
DTH2_k127_4596593_1 transmembrane transporter activity K03296 - - 0.0 1118.0
DTH2_k127_4596593_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 302.0
DTH2_k127_4596593_3 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000384 278.0
DTH2_k127_4596593_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003724 286.0
DTH2_k127_4596593_5 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000003599 236.0
DTH2_k127_4600939_0 Mo-co oxidoreductase dimerisation domain K17225 - - 1.078e-217 682.0
DTH2_k127_4600939_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 353.0
DTH2_k127_4600939_2 Cytochrome c K08738 - - 0.0000000000000000000000000000001131 126.0
DTH2_k127_4600939_3 Transcriptional regulator, ArsR family - - - 0.00000000000000000000000000001246 121.0
DTH2_k127_4600939_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000006807 54.0
DTH2_k127_4635101_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 1845.0
DTH2_k127_4635101_1 Fe-S cluster K03616 - - 0.0000000000000001787 80.0
DTH2_k127_4674009_0 Bacterial protein of unknown function (DUF885) - - - 4.217e-199 635.0
DTH2_k127_4674009_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000009761 219.0
DTH2_k127_4674009_2 Mandelate racemase muconate lactonizing K18983 - 5.5.1.27 0.000000000000000000000000000000000000000000004776 175.0
DTH2_k127_4727096_0 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000009848 180.0
DTH2_k127_4727096_1 PA domain K14647 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000518 156.0
DTH2_k127_4727096_2 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000006388 160.0
DTH2_k127_4727096_3 - - - - 0.00000003348 63.0
DTH2_k127_4751875_0 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 301.0
DTH2_k127_4751875_1 Thrombospondin type 3 repeat - - - 0.0000000000000000000000782 115.0
DTH2_k127_4751875_2 Beta-propeller repeat - - - 0.000000000000000000002167 111.0
DTH2_k127_4751875_3 regulation of response to stimulus - - - 0.0000000000001383 85.0
DTH2_k127_4751875_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000002392 74.0
DTH2_k127_4751875_5 Transposase K07491 - - 0.000000001656 63.0
DTH2_k127_4753594_0 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 317.0
DTH2_k127_4753594_1 domain protein - - - 0.0000000000000000000000000000000000000000000000007303 198.0
DTH2_k127_4753594_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000006402 109.0
DTH2_k127_4775719_0 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 520.0
DTH2_k127_4775719_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 425.0
DTH2_k127_4775719_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 406.0
DTH2_k127_4784343_0 Involved in the processing of the 5'end of 16S rRNA K08301 - - 1.408e-194 619.0
DTH2_k127_4784343_1 membrane - - - 0.0000000000000000000000000000000000000000007153 179.0
DTH2_k127_4784343_2 Maf-like protein K06287 - - 0.000000000000000000000000000005805 122.0
DTH2_k127_4807803_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 571.0
DTH2_k127_4807803_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 490.0
DTH2_k127_4807803_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 349.0
DTH2_k127_4807803_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000001083 114.0
DTH2_k127_4807803_4 Oxygen-independent coproporphyrinogen III oxidase - - - 0.00000000004526 63.0
DTH2_k127_4815964_0 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001828 214.0
DTH2_k127_4815964_1 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000000000000104 203.0
DTH2_k127_4815964_2 glyoxalase K06996 - - 0.00000000000000000000000000000000000000000000000007988 179.0
DTH2_k127_4815964_3 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000002731 162.0
DTH2_k127_4815964_4 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000001289 136.0
DTH2_k127_4815964_5 Domain of unknown function (DUF5086) - - - 0.00000000000000000000000006564 113.0
DTH2_k127_4815964_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000007981 78.0
DTH2_k127_4838500_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 571.0
DTH2_k127_4838500_2 protein conserved in bacteria K09920 - - 0.0000000006049 68.0
DTH2_k127_4937928_0 (ABC) transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 557.0
DTH2_k127_4937928_1 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000003131 205.0
DTH2_k127_5002223_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.575e-216 698.0
DTH2_k127_5002223_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 441.0
DTH2_k127_5002223_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 333.0
DTH2_k127_5019576_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 388.0
DTH2_k127_5019576_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 343.0
DTH2_k127_5019576_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000801 292.0
DTH2_k127_5019576_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 265.0
DTH2_k127_5019576_4 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000002615 139.0
DTH2_k127_5019576_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000003955 68.0
DTH2_k127_5022621_0 Carbamoyl-phosphate synthase L chain, ATP binding domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 486.0
DTH2_k127_5022621_1 Mur ligase family, glutamate ligase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 469.0
DTH2_k127_5022621_2 PFAM Cys Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 426.0
DTH2_k127_5022621_3 thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009334 271.0
DTH2_k127_5092572_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 4.408e-305 963.0
DTH2_k127_5092572_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 8.925e-209 685.0
DTH2_k127_5092572_2 Pyridoxal-phosphate dependent enzyme K01738,K01912 - 2.5.1.47,6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 536.0
DTH2_k127_5092572_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 367.0
DTH2_k127_5092572_4 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001287 237.0
DTH2_k127_5098034_0 Phage tail sheath protein subtilisin-like domain K06907 - - 1.944e-284 885.0
DTH2_k127_5098034_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000005963 172.0
DTH2_k127_5098034_2 PFAM Peptidase M1 membrane alanine aminopeptidase - - - 0.0000000000000007041 80.0
DTH2_k127_5118143_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.195e-225 708.0
DTH2_k127_5118143_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 536.0
DTH2_k127_5118143_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 299.0
DTH2_k127_5118143_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000007201 135.0
DTH2_k127_5118143_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001286 128.0
DTH2_k127_5127562_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1069.0
DTH2_k127_5127562_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 590.0
DTH2_k127_5127562_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 460.0
DTH2_k127_5127562_3 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 391.0
DTH2_k127_5127562_4 transcriptional regulator K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 327.0
DTH2_k127_5144368_0 Cation transporter/ATPase, N-terminus - - - 1.622e-317 996.0
DTH2_k127_5144368_1 Belongs to the aldehyde dehydrogenase family K00130,K00138 - 1.2.1.8 1.162e-225 705.0
DTH2_k127_5153929_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 373.0
DTH2_k127_5153929_1 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 346.0
DTH2_k127_5153929_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000005205 236.0
DTH2_k127_5153929_3 EF-hand, calcium binding motif - - - 0.0000000000000006976 79.0
DTH2_k127_5153929_4 Transcription factor zinc-finger - - - 0.00003168 53.0
DTH2_k127_5162677_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 545.0
DTH2_k127_5162677_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 524.0
DTH2_k127_5162677_10 TonB dependent receptor K16092 - - 0.0000000000001949 71.0
DTH2_k127_5162677_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 322.0
DTH2_k127_5162677_3 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 298.0
DTH2_k127_5162677_4 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 291.0
DTH2_k127_5162677_5 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000008243 248.0
DTH2_k127_5162677_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000001362 212.0
DTH2_k127_5162677_7 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000006855 145.0
DTH2_k127_5162677_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000001167 138.0
DTH2_k127_5162677_9 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.000000000000000000000000000003946 132.0
DTH2_k127_5203962_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.602e-195 627.0
DTH2_k127_5203962_1 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000002261 178.0
DTH2_k127_5217727_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 571.0
DTH2_k127_5217727_1 cytochrome K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001805 272.0
DTH2_k127_5217727_2 PFAM Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000000000000000000000006602 223.0
DTH2_k127_5217727_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000008586 213.0
DTH2_k127_5217727_4 stringent starvation protein b K03600 - - 0.000000000000000000000000000000000000001647 151.0
DTH2_k127_5217727_5 PFAM Smr - - - 0.000000000000000000004939 96.0
DTH2_k127_5217727_6 Protein of unknown function (DUF3301) - - - 0.0000000005494 67.0
DTH2_k127_5244385_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.365e-256 801.0
DTH2_k127_5244385_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 478.0
DTH2_k127_5244385_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 471.0
DTH2_k127_5244385_3 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 359.0
DTH2_k127_5244385_4 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 358.0
DTH2_k127_5244385_5 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.00000000000000000000000001275 113.0
DTH2_k127_5259777_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 446.0
DTH2_k127_5259777_1 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000000000000005015 138.0
DTH2_k127_5261366_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 8.933e-266 827.0
DTH2_k127_5261366_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 533.0
DTH2_k127_5261366_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 523.0
DTH2_k127_5261366_3 Uncharacterized lipoprotein K07286 - - 0.0000000000000000000000000000000000000000000000000000000000000002207 227.0
DTH2_k127_5261366_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000009579 194.0
DTH2_k127_5261366_5 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000003123 187.0
DTH2_k127_5262292_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1145.0
DTH2_k127_5262292_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 369.0
DTH2_k127_5262292_2 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 286.0
DTH2_k127_5262292_3 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000001963 198.0
DTH2_k127_5262292_4 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000001044 142.0
DTH2_k127_5292797_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1155.0
DTH2_k127_5292797_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 514.0
DTH2_k127_5292797_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000516 220.0
DTH2_k127_5292797_3 HNH nucleases - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000003916 180.0
DTH2_k127_5292797_4 transport system, small permease component - - - 0.000000000000000000000000000000000000000000008672 169.0
DTH2_k127_5292797_5 glycosyl transferase family 8 - - - 0.0000000000000000000000001246 118.0
DTH2_k127_5292797_6 Protein of unknown function (DUF2782) - - - 0.0000000000000003111 83.0
DTH2_k127_5313706_0 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 381.0
DTH2_k127_5313706_1 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 348.0
DTH2_k127_5313706_2 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 323.0
DTH2_k127_5313706_3 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 316.0
DTH2_k127_5313706_4 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000008273 214.0
DTH2_k127_5317113_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 8.803e-202 636.0
DTH2_k127_5317113_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 610.0
DTH2_k127_5317113_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 585.0
DTH2_k127_5317113_3 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 463.0
DTH2_k127_5317113_4 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 394.0
DTH2_k127_5317113_5 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000001472 271.0
DTH2_k127_5317113_6 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000007152 214.0
DTH2_k127_5317113_7 multidrug K03327 - - 0.00000000000000000000000000000000000000000000000000000001686 205.0
DTH2_k127_5317113_8 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000000000000000000002501 208.0
DTH2_k127_5321862_0 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 388.0
DTH2_k127_5321862_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002215 279.0
DTH2_k127_5321862_2 cellular modified histidine biosynthetic process K18802 - - 0.000000000003836 68.0
DTH2_k127_5321862_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 0.0005673 46.0
DTH2_k127_5327861_0 Phosphorylase superfamily K01241 - 3.2.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 419.0
DTH2_k127_5327861_1 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 325.0
DTH2_k127_5327861_2 Belongs to the DnaA family. HdA subfamily K10763 - - 0.000000000000000000000000000000000000000000000005745 181.0
DTH2_k127_5327861_3 - - - - 0.000000000000000000000000000000000000000001184 174.0
DTH2_k127_5327861_4 protein conserved in bacteria K09938 - - 0.0000000104 62.0
DTH2_k127_535394_0 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847,K01848 GO:0003674,GO:0003824,GO:0004494,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0019842,GO:0031419,GO:0036094,GO:0046906,GO:0048037,GO:0097159,GO:1901363 5.4.99.2 5.564e-296 917.0
DTH2_k127_535394_1 malonyl CoA-acyl carrier protein transacylase K00645,K13935 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 336.0
DTH2_k127_535394_2 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000003535 111.0
DTH2_k127_5355388_0 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000006686 169.0
DTH2_k127_5355388_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000001062 106.0
DTH2_k127_5355388_2 PFAM SMP-30 Gluconolaconase - - - 0.000003329 57.0
DTH2_k127_536609_0 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 324.0
DTH2_k127_536609_1 Domain of unknown function (DUF4150) - - - 0.00000000000000000000000000000000000000000000000000000000883 201.0
DTH2_k127_536609_2 - - - - 0.0000000000000000000000000000001099 131.0
DTH2_k127_536609_3 - - - - 0.00000000000000000000004756 114.0
DTH2_k127_536609_4 synthase K00647 - 2.3.1.41 0.0000000000009955 72.0
DTH2_k127_536609_5 - - - - 0.0000000001024 70.0
DTH2_k127_536609_6 Tetratricopeptide repeats - - - 0.000006265 54.0
DTH2_k127_5376190_0 AMP-binding enzyme C-terminal domain K00666,K02182,K20034 - 6.2.1.44,6.2.1.48 1.037e-226 713.0
DTH2_k127_5376190_1 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 376.0
DTH2_k127_5376190_2 - - - - 0.0000000000000000000000000000000000000005068 159.0
DTH2_k127_5376190_3 - - - - 0.0000000000000006732 80.0
DTH2_k127_5399262_0 overlaps another CDS with the same product name K11720 - - 0.00000000000000000000000000000000000000000000000000000009527 208.0
DTH2_k127_5399262_1 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000006344 155.0
DTH2_k127_5399262_2 RDD family - - - 0.0000000000000000000000002628 110.0
DTH2_k127_5404086_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 437.0
DTH2_k127_5404086_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 402.0
DTH2_k127_5404086_2 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 369.0
DTH2_k127_5404086_3 acyl-coa dehydrogenase K09456 - - 0.00000000000000000000000000000000000000000000000000000000001015 213.0
DTH2_k127_5404086_4 Conserved carboxylase domain K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000001132 209.0
DTH2_k127_5404086_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000002057 112.0
DTH2_k127_5404086_6 - - - - 0.0000003143 61.0
DTH2_k127_5404086_7 - - - - 0.00001898 55.0
DTH2_k127_5436494_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 604.0
DTH2_k127_5436494_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 414.0
DTH2_k127_5436494_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
DTH2_k127_5436494_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000222 81.0
DTH2_k127_5449806_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 1.854e-254 798.0
DTH2_k127_5449806_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 432.0
DTH2_k127_5449806_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000001015 194.0
DTH2_k127_5452451_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.203e-274 865.0
DTH2_k127_5452451_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 496.0
DTH2_k127_5452451_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001351 279.0
DTH2_k127_5452451_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000001337 160.0
DTH2_k127_5452451_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000001752 149.0
DTH2_k127_5498451_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 471.0
DTH2_k127_5498451_1 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000001768 222.0
DTH2_k127_5498451_2 Phosphoglycerate mutase family - - - 0.00000000000000000000000000005384 124.0
DTH2_k127_5546863_0 FAD dependent oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 563.0
DTH2_k127_5546863_1 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 423.0
DTH2_k127_5546863_2 Outer Membrane Lipoprotein K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009813 240.0
DTH2_k127_5546863_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000375 157.0
DTH2_k127_5546863_4 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000005783 146.0
DTH2_k127_5546863_5 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000006576 122.0
DTH2_k127_5560392_0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 486.0
DTH2_k127_5560392_1 UPF0056 membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000003927 205.0
DTH2_k127_5560392_3 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0001651 44.0
DTH2_k127_5560392_4 Domain of unknown function (DUF2088) - - - 0.0003638 46.0
DTH2_k127_559693_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.354e-298 929.0
DTH2_k127_559693_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 403.0
DTH2_k127_559693_2 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000004958 217.0
DTH2_k127_559693_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000003157 87.0
DTH2_k127_567914_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 567.0
DTH2_k127_567914_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 453.0
DTH2_k127_567914_2 TIGRFAM TonB-dependent heme hemoglobin receptor family protein K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 332.0
DTH2_k127_567914_3 PFAM glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000106 283.0
DTH2_k127_567914_4 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000005526 138.0
DTH2_k127_567914_5 Aldehyde dehydrogenase family - - - 0.00000000000000000001675 94.0
DTH2_k127_568220_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 359.0
DTH2_k127_568220_1 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 301.0
DTH2_k127_568220_2 acetyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000009652 198.0
DTH2_k127_5692211_0 Large extracellular alpha-helical protein - - - 0.0000000000000000000000000000000000000000000000000000000001075 234.0
DTH2_k127_5692211_1 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000005354 209.0
DTH2_k127_5692211_2 chaperone-mediated protein folding - - - 0.00000000000000002819 96.0
DTH2_k127_5714082_0 FAD linked oxidase K00104 - 1.1.3.15 3.63e-213 672.0
DTH2_k127_5714082_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 414.0
DTH2_k127_5714082_2 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
DTH2_k127_5714082_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000006985 139.0
DTH2_k127_5778788_0 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 401.0
DTH2_k127_5778788_1 - - - - 0.0000000000000006301 93.0
DTH2_k127_5778788_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000004405 80.0
DTH2_k127_5802585_0 protein conserved in bacteria - - - 1.188e-237 749.0
DTH2_k127_5802585_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 407.0
DTH2_k127_5802585_2 COG0534 Na -driven multidrug efflux pump K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 327.0
DTH2_k127_5802585_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000005557 211.0
DTH2_k127_5802585_4 - - - - 0.000000000000000000000000006243 120.0
DTH2_k127_5802585_5 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000001694 90.0
DTH2_k127_5820380_0 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 396.0
DTH2_k127_5820380_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000008111 166.0
DTH2_k127_5820380_3 transporter - - - 0.0000000000000000001145 96.0
DTH2_k127_5865896_0 Acetyl-CoA dehydrogenase C-terminal like K20035 - - 2.936e-226 712.0
DTH2_k127_5865896_1 FAD binding domain K07077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 603.0
DTH2_k127_5865896_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 344.0
DTH2_k127_589233_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 288.0
DTH2_k127_589233_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002127 270.0
DTH2_k127_589233_2 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003866 265.0
DTH2_k127_589233_3 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000002474 226.0
DTH2_k127_589233_4 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000001402 119.0
DTH2_k127_589233_5 Predicted integral membrane protein (DUF2189) - - - 0.0000000000007743 72.0
DTH2_k127_5904673_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 408.0
DTH2_k127_5904673_1 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 355.0
DTH2_k127_5904673_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 327.0
DTH2_k127_5904673_3 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001798 247.0
DTH2_k127_5904673_4 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000005013 194.0
DTH2_k127_5904673_5 - - - - 0.000001573 57.0
DTH2_k127_5920399_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.065e-272 849.0
DTH2_k127_5920399_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 454.0
DTH2_k127_5920399_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000287 78.0
DTH2_k127_5920399_2 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 442.0
DTH2_k127_5920399_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002483 286.0
DTH2_k127_5920399_4 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000102 274.0
DTH2_k127_5920399_5 COG2303 Choline dehydrogenase and related flavoproteins K06151 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
DTH2_k127_5920399_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000004274 259.0
DTH2_k127_5920399_7 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003287 245.0
DTH2_k127_5920399_8 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000003346 159.0
DTH2_k127_5920399_9 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K06149 - - 0.0000000000000000000000000000000008505 135.0
DTH2_k127_5923698_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1077.0
DTH2_k127_5923698_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.965e-243 783.0
DTH2_k127_5923698_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000002104 203.0
DTH2_k127_5936471_0 von willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 588.0
DTH2_k127_5936471_1 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 405.0
DTH2_k127_5936471_2 Uncharacterized protein family UPF0029 - - - 0.0000000000000000000000000000000000000000000000006911 181.0
DTH2_k127_5936471_3 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000008406 157.0
DTH2_k127_5944763_0 Cysteine-rich domain K21834 - - 3.236e-229 715.0
DTH2_k127_5944763_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 437.0
DTH2_k127_5944763_2 Nickel-dependent hydrogenase K05922,K06281 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 384.0
DTH2_k127_5944763_3 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 293.0
DTH2_k127_5944763_4 - - - - 0.00000000000000000000000000000000000000000002536 166.0
DTH2_k127_5962909_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 452.0
DTH2_k127_5962909_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 391.0
DTH2_k127_5962909_2 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 357.0
DTH2_k127_5962909_3 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 290.0
DTH2_k127_5988734_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 374.0
DTH2_k127_5988734_1 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000553 288.0
DTH2_k127_5988734_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001406 265.0
DTH2_k127_5988734_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000003018 200.0
DTH2_k127_5988734_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000002759 186.0
DTH2_k127_5988734_5 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000006835 94.0
DTH2_k127_5988734_6 Kdo2-lipid A biosynthetic process - - - 0.000000000004239 78.0
DTH2_k127_5994785_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1235.0
DTH2_k127_5994785_1 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000008674 144.0
DTH2_k127_5994785_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000003735 64.0
DTH2_k127_6028437_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 360.0
DTH2_k127_6028437_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 329.0
DTH2_k127_6028437_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000001012 258.0
DTH2_k127_6028437_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000004102 216.0
DTH2_k127_6028437_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000001959 166.0
DTH2_k127_6028437_5 Thioredoxin - - - 0.00000000000000000000000000000000006845 138.0
DTH2_k127_6029570_0 Dehydrogenase E1 component K11381 - 1.2.4.4 4.39e-301 938.0
DTH2_k127_6029570_1 Aldehyde dehydrogenase K02618 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.2.1.91,3.3.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 576.0
DTH2_k127_6029570_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 389.0
DTH2_k127_6029570_3 COG1522 Transcriptional regulators K03719,K05800 - - 0.0000000000000000000000000000000000000004319 153.0
DTH2_k127_6029570_4 Aminotransferase class-V - - - 0.000000000000000009059 89.0
DTH2_k127_6047602_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 294.0
DTH2_k127_6047602_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000003531 226.0
DTH2_k127_6047602_2 - - - - 0.00000000000000000000000000000000000000000000000000000002239 203.0
DTH2_k127_6047602_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000005497 152.0
DTH2_k127_6047602_4 Histidine kinase - - - 0.000000000000004092 81.0
DTH2_k127_6047602_5 FHA domain - - - 0.00000000001362 70.0
DTH2_k127_6057492_0 Beta-eliminating lyase K01668 - 4.1.99.2 1.006e-212 671.0
DTH2_k127_6057492_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 340.0
DTH2_k127_6057492_2 helix_turn_helix ASNC type K05800 - - 0.000000000000000000000000000000000001562 143.0
DTH2_k127_6057492_3 peptidase - - - 0.000000000000000003052 91.0
DTH2_k127_6061528_0 Gp5 C-terminal repeat (3 copies) K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 440.0
DTH2_k127_6061528_1 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009575 261.0
DTH2_k127_6061528_2 synthase K00647 - 2.3.1.41 0.000000000000000000000000000000000000001124 161.0
DTH2_k127_6061528_3 Domain of unknown function (DUF4150) - - - 0.000000000009222 65.0
DTH2_k127_6120598_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 1.031e-223 701.0
DTH2_k127_6120598_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 478.0
DTH2_k127_6120598_2 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
DTH2_k127_6120598_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002149 302.0
DTH2_k127_6120598_4 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000678 98.0
DTH2_k127_6133657_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 7.253e-265 832.0
DTH2_k127_6133657_1 Fatty acid desaturase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 599.0
DTH2_k127_6133657_2 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 582.0
DTH2_k127_6133657_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 333.0
DTH2_k127_6133657_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000008023 236.0
DTH2_k127_6133657_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000375 136.0
DTH2_k127_6133672_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 614.0
DTH2_k127_6133672_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 311.0
DTH2_k127_6139883_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 526.0
DTH2_k127_6139883_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 314.0
DTH2_k127_6139883_2 Amino acid kinase family K12524,K12525 GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000004387 217.0
DTH2_k127_6139883_3 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000003004 128.0
DTH2_k127_6141417_0 TonB-dependent receptor plug - - - 6.66e-230 732.0
DTH2_k127_6141417_1 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 431.0
DTH2_k127_6170100_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 348.0
DTH2_k127_6170100_1 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000001179 140.0
DTH2_k127_6170100_2 Belongs to the UPF0145 family - - - 0.00000000000000000000001768 110.0
DTH2_k127_618624_0 Pfam Amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 598.0
DTH2_k127_618624_1 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 545.0
DTH2_k127_618624_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 505.0
DTH2_k127_618624_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 511.0
DTH2_k127_618624_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 461.0
DTH2_k127_618624_5 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 370.0
DTH2_k127_618624_6 4Fe-4S dicluster domain K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 339.0
DTH2_k127_618624_7 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000001655 243.0
DTH2_k127_618624_8 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000001376 118.0
DTH2_k127_618624_9 hemerythrin-like metal-binding K07216 - - 0.00000000001065 71.0
DTH2_k127_6194293_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 515.0
DTH2_k127_6194293_1 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 355.0
DTH2_k127_6194293_2 abc transporter, permease K09015 - - 0.00000000000000000000000000000000000000000000000000000000000003628 223.0
DTH2_k127_6194897_0 N-carbamoylputrescine amidase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 437.0
DTH2_k127_6194897_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 293.0
DTH2_k127_6194897_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002131 259.0
DTH2_k127_6194897_3 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001004 244.0
DTH2_k127_6194897_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000001228 119.0
DTH2_k127_6194897_5 alpha/beta hydrolase fold - - - 0.000000000000008559 79.0
DTH2_k127_6236931_0 type VI secretion protein K11896 - - 1.836e-206 659.0
DTH2_k127_6236931_1 ImpE protein K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
DTH2_k127_6236931_2 Pfam:T6SS_VasB K11895 - - 0.00000000000000000000000000000000000000000000000000000000000349 214.0
DTH2_k127_6236931_3 type VI secretion protein K11900 - - 0.00000000000000000000000000000000000000000000000000000001753 198.0
DTH2_k127_6236931_4 TIGRFAM Type VI secretion system, lysozyme-related K11897 - - 0.00000000000000000000000000000000000000000008945 164.0
DTH2_k127_6236931_5 type VI secretion system effector, Hcp1 family K11903 - - 0.00000001275 62.0
DTH2_k127_6282799_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1160.0
DTH2_k127_6282799_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 617.0
DTH2_k127_6282799_10 Domain of unknown function (DUF1820) - - - 0.000000000000000000000000006705 113.0
DTH2_k127_6282799_11 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000001007 115.0
DTH2_k127_6282799_12 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000001467 65.0
DTH2_k127_6282799_13 Type II secretion system protein B K02451 - - 0.000000002783 60.0
DTH2_k127_6282799_2 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 425.0
DTH2_k127_6282799_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 389.0
DTH2_k127_6282799_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 338.0
DTH2_k127_6282799_5 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000641 266.0
DTH2_k127_6282799_6 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000004756 240.0
DTH2_k127_6282799_7 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000000000000000000008018 185.0
DTH2_k127_6282799_8 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000001431 179.0
DTH2_k127_6282799_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.00000000000000000000000000000000000000000000003142 176.0
DTH2_k127_6282818_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1061.0
DTH2_k127_6282818_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 321.0
DTH2_k127_6282818_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003476 272.0
DTH2_k127_6282818_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000002049 240.0
DTH2_k127_6282818_4 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000007083 187.0
DTH2_k127_6287077_0 - - - - 0.0 1113.0
DTH2_k127_6287077_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 562.0
DTH2_k127_6287077_2 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 494.0
DTH2_k127_6287077_3 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 405.0
DTH2_k127_6287077_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000005938 191.0
DTH2_k127_6287077_5 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000002787 147.0
DTH2_k127_6287077_6 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000003615 102.0
DTH2_k127_6300018_0 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K15022 - 1.17.1.10 2.039e-294 912.0
DTH2_k127_6300018_1 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 5.144e-265 827.0
DTH2_k127_6300018_2 asparagine synthase, glutamine-hydrolyzing K01953 GO:0000166,GO:0003674,GO:0003824,GO:0004066,GO:0004071,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006541,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016054,GO:0016211,GO:0016597,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0017076,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 6.3.5.4 1.055e-253 795.0
DTH2_k127_6300018_3 Sulfatase K03760 - 2.7.8.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 521.0
DTH2_k127_6300018_4 PUA-like domain K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 505.0
DTH2_k127_6300018_5 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 458.0
DTH2_k127_6300018_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 428.0
DTH2_k127_6300018_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 296.0
DTH2_k127_6300018_8 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000006877 178.0
DTH2_k127_6300018_9 HIT family hydrolase, diadenosine tetraphosphate hydrolase - - - 0.0000000000000000000000000000000000000000000004115 170.0
DTH2_k127_6338838_0 Belongs to the RimK family K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 486.0
DTH2_k127_6338838_1 PFAM Succinylglutamate desuccinylase Aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 415.0
DTH2_k127_6338838_2 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000004677 180.0
DTH2_k127_6384673_0 ABC-type multidrug transport system ATPase and permease K06147 - - 4.403e-291 903.0
DTH2_k127_6384673_1 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 536.0
DTH2_k127_6384673_2 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 517.0
DTH2_k127_6384673_3 COGs COG5616 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 343.0
DTH2_k127_6384673_4 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 307.0
DTH2_k127_6384673_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
DTH2_k127_6384673_6 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000004961 98.0
DTH2_k127_6384673_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001093 89.0
DTH2_k127_6389464_0 Type II secretory pathway, component HofQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 537.0
DTH2_k127_6389464_1 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000001304 196.0
DTH2_k127_6389464_2 assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000001807 156.0
DTH2_k127_6389464_3 pilus assembly protein PilP K02665 - - 0.00000000000000000000000000000000000008559 148.0
DTH2_k127_6395730_0 Sortilin, neurotensin receptor 3, - - - 0.0 1244.0
DTH2_k127_6395730_1 Protein of unknown function (DUF1214) - - - 7.545e-224 704.0
DTH2_k127_6395730_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000006843 169.0
DTH2_k127_6395730_3 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.0000000000000000000000001954 109.0
DTH2_k127_6399204_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 6.519e-200 631.0
DTH2_k127_6399204_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 487.0
DTH2_k127_6399204_2 Regulator of competence-specific genes - - - 0.0000000000000000000000000000000000000001807 153.0
DTH2_k127_6399204_3 Cupin domain - - - 0.0000000000000000000000000000001964 126.0
DTH2_k127_6403753_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 3.209e-196 625.0
DTH2_k127_6403753_1 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 582.0
DTH2_k127_6403753_2 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000002427 254.0
DTH2_k127_6403753_3 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000001696 203.0
DTH2_k127_6403753_4 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000004558 188.0
DTH2_k127_6409324_0 Phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 4.44e-219 692.0
DTH2_k127_6409324_1 phosphonopyruvate decarboxylase K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 411.0
DTH2_k127_6409324_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000001898 248.0
DTH2_k127_6409324_3 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001537 248.0
DTH2_k127_6409324_4 methyltransferase activity - - - 0.000000000000000000000000000000002341 136.0
DTH2_k127_6417155_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1291.0
DTH2_k127_6417155_1 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 351.0
DTH2_k127_6457543_0 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 482.0
DTH2_k127_6457543_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 450.0
DTH2_k127_6457543_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005258 241.0
DTH2_k127_6457543_3 ACT domain - - - 0.000000000000000000000000000000000000003459 151.0
DTH2_k127_6457543_4 cAMP biosynthetic process - - - 0.00005647 50.0
DTH2_k127_6468755_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 381.0
DTH2_k127_6468755_1 COG4974 Site-specific recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 352.0
DTH2_k127_6468755_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000001919 227.0
DTH2_k127_6480347_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 548.0
DTH2_k127_6480347_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
DTH2_k127_6480347_2 FeoA K04758 - - 0.00004089 48.0
DTH2_k127_6511261_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 528.0
DTH2_k127_6511261_1 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 385.0
DTH2_k127_6511261_2 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001578 241.0
DTH2_k127_6526904_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 424.0
DTH2_k127_6526904_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000002911 164.0
DTH2_k127_6552443_0 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 379.0
DTH2_k127_6552443_1 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 339.0
DTH2_k127_6552443_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000003204 121.0
DTH2_k127_6577089_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 387.0
DTH2_k127_6577089_1 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 372.0
DTH2_k127_6577089_2 proteins of the AP superfamily - - - 0.0000000000003921 75.0
DTH2_k127_6605227_0 General secretion pathway protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 509.0
DTH2_k127_6605227_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 297.0
DTH2_k127_6605227_2 Type II secretion system protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000009735 244.0
DTH2_k127_6605227_3 General secretion pathway protein K02461 - - 0.000000000000000000000000000000000000000000000000008405 194.0
DTH2_k127_6605227_4 General secretion pathway protein K02462 - - 0.0000000000000007239 85.0
DTH2_k127_6605227_5 - - - - 0.000000000001337 74.0
DTH2_k127_6605227_6 general secretion pathway protein - - - 0.00000000444 67.0
DTH2_k127_6635827_0 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 430.0
DTH2_k127_6635827_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 361.0
DTH2_k127_6635827_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002556 282.0
DTH2_k127_6635827_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 250.0
DTH2_k127_6635827_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001621 253.0
DTH2_k127_6635827_5 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000001107 227.0
DTH2_k127_6651564_0 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 614.0
DTH2_k127_6651564_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 411.0
DTH2_k127_6655280_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 494.0
DTH2_k127_6655280_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 472.0
DTH2_k127_6655280_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000009804 122.0
DTH2_k127_6655280_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 464.0
DTH2_k127_6655280_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 328.0
DTH2_k127_6655280_4 Lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 311.0
DTH2_k127_6655280_5 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000421 278.0
DTH2_k127_6655280_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004489 273.0
DTH2_k127_6655280_7 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000007096 177.0
DTH2_k127_6655280_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000001231 161.0
DTH2_k127_6655280_9 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000003042 153.0
DTH2_k127_6662609_0 RNA-metabolising metallo-beta-lactamase K07576 - - 2.248e-215 676.0
DTH2_k127_6662609_1 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 542.0
DTH2_k127_6662609_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 456.0
DTH2_k127_6662609_3 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 391.0
DTH2_k127_6662609_4 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000000000008736 168.0
DTH2_k127_6662609_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000002086 83.0
DTH2_k127_6662609_6 Pas domain - - - 0.00000000000005443 84.0
DTH2_k127_6662609_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000005847 67.0
DTH2_k127_6662609_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00000001312 61.0
DTH2_k127_6672538_0 ABC transporter - - - 1.303e-242 756.0
DTH2_k127_6672538_1 epimerase - - - 0.0000000000000000000000000000000000000000000000004085 187.0
DTH2_k127_6672538_2 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000007311 121.0
DTH2_k127_6675313_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.224e-214 672.0
DTH2_k127_6675313_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 7.871e-198 652.0
DTH2_k127_6675313_2 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 312.0
DTH2_k127_6675313_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 297.0
DTH2_k127_6675313_4 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000005067 233.0
DTH2_k127_6675313_5 Zinc-finger domain - - - 0.0000000000000000002417 89.0
DTH2_k127_6740590_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 7.194e-262 815.0
DTH2_k127_6740590_1 Acyltransferase - - - 9.072e-212 675.0
DTH2_k127_6740590_10 PFAM glutaredoxin 2 - - - 0.00000000000000002059 84.0
DTH2_k127_6740590_2 Serine dehydratase K01752 - 4.3.1.17 6.234e-209 657.0
DTH2_k127_6740590_3 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 557.0
DTH2_k127_6740590_4 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 413.0
DTH2_k127_6740590_5 Dak2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 344.0
DTH2_k127_6740590_6 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001827 284.0
DTH2_k127_6740590_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003829 243.0
DTH2_k127_6740590_8 Peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000005594 186.0
DTH2_k127_6740806_0 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 445.0
DTH2_k127_6740806_1 Quinone oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 371.0
DTH2_k127_6768745_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 446.0
DTH2_k127_6768745_1 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 433.0
DTH2_k127_6768745_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 414.0
DTH2_k127_6768745_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 403.0
DTH2_k127_6768745_4 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.0000000001461 66.0
DTH2_k127_677106_0 Allantoinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 478.0
DTH2_k127_677106_1 Belongs to the allantoicase family K01477 - 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 351.0
DTH2_k127_677106_2 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001191 239.0
DTH2_k127_677106_3 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.00000000000000000000000000000000000000000004473 163.0
DTH2_k127_677106_4 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source K01483 - 4.3.2.3 0.000000000000000000000000000000000000000124 158.0
DTH2_k127_677106_5 OHCU decarboxylase - - - 0.0000000000000000000000000000000000001486 146.0
DTH2_k127_677106_6 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.000008864 48.0
DTH2_k127_677820_0 transferase activity, transferring nitrogenous groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 440.0
DTH2_k127_677820_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000008332 219.0
DTH2_k127_677820_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000004278 219.0
DTH2_k127_677820_3 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000005119 207.0
DTH2_k127_677820_4 sequence-specific DNA binding K13655 - - 0.000000000000000000007215 96.0
DTH2_k127_6832765_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 607.0
DTH2_k127_6832765_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 402.0
DTH2_k127_6832765_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
DTH2_k127_6832765_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002432 279.0
DTH2_k127_6832765_4 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000001911 247.0
DTH2_k127_6832765_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000003832 213.0
DTH2_k127_6832765_6 Tfp pilus assembly protein FimV K08086 - - 0.000000004148 57.0
DTH2_k127_6861449_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 338.0
DTH2_k127_6861449_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000003753 159.0
DTH2_k127_6861449_2 - - - - 0.000000000000711 72.0
DTH2_k127_6865928_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 429.0
DTH2_k127_6865928_1 Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 365.0
DTH2_k127_6865928_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 271.0
DTH2_k127_6885123_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 316.0
DTH2_k127_6885123_1 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
DTH2_k127_6885123_2 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002078 250.0
DTH2_k127_6885123_3 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000000000000000000000000000000000000000004091 207.0
DTH2_k127_6885123_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000003255 77.0
DTH2_k127_6915660_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 529.0
DTH2_k127_6915660_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
DTH2_k127_6915660_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000215 228.0
DTH2_k127_6915660_3 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000001675 99.0
DTH2_k127_6925490_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002242 239.0
DTH2_k127_6925490_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000001135 127.0
DTH2_k127_6925490_2 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000001652 94.0
DTH2_k127_6925490_3 6-phosphogluconolactonase activity - - - 0.000000000000008045 89.0
DTH2_k127_6925490_4 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 0.000004927 49.0
DTH2_k127_6962656_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 5.771e-286 897.0
DTH2_k127_6962656_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 285.0
DTH2_k127_6962656_2 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000001181 218.0
DTH2_k127_7037720_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 349.0
DTH2_k127_7037720_1 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 316.0
DTH2_k127_7037720_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000276 251.0
DTH2_k127_7037720_3 Metal-dependent phosphohydrolase K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000005058 241.0
DTH2_k127_7037720_4 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000001242 192.0
DTH2_k127_7037720_5 CMP dCMP deaminase, zinc-binding - - - 0.00000000000000000000000000000000000000000000000004111 186.0
DTH2_k127_7037720_6 YCII-related domain K09780 - - 0.00000000000000000000000000000000008188 135.0
DTH2_k127_7037720_7 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000001298 124.0
DTH2_k127_7037720_8 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000132 113.0
DTH2_k127_7068103_0 Type VI secretion protein, VC_A0114 family K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 361.0
DTH2_k127_7068103_1 Type VI secretion K07169,K11894,K11913 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005763 257.0
DTH2_k127_7068103_2 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 K11906 - - 0.0000000000000000000002893 102.0
DTH2_k127_7094910_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.236e-263 815.0
DTH2_k127_7094910_1 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000001421 144.0
DTH2_k127_7094910_2 succinate dehydrogenase K00242 - - 0.000000000000000000000003655 108.0
DTH2_k127_7094910_3 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000001043 105.0
DTH2_k127_7120273_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 568.0
DTH2_k127_7120273_1 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000000008865 206.0
DTH2_k127_7120273_2 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000000000000000000000000000000000001927 186.0
DTH2_k127_7120273_3 - - - - 0.0000000000000000000000000000000000001085 148.0
DTH2_k127_7120273_4 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.00000000000000000000000000000005214 126.0
DTH2_k127_7160931_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 407.0
DTH2_k127_7160931_1 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003059 279.0
DTH2_k127_7160931_2 Exodeoxyribonuclease IX - - - 0.0000000000000000000000000000000000000000000000000000000003096 207.0
DTH2_k127_7275617_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 589.0
DTH2_k127_7275617_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 382.0
DTH2_k127_7275617_2 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003868 278.0
DTH2_k127_7275617_3 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002212 273.0
DTH2_k127_7278052_0 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002708 262.0
DTH2_k127_7278052_1 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000002493 224.0
DTH2_k127_7278052_2 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000001286 189.0
DTH2_k127_7278052_3 Membrane protein required for beta-lactamase induction K03807 - - 0.0000000000000000000000000000000000000000000004306 178.0
DTH2_k127_7278052_4 TspO/MBR family K05770 - - 0.0000000000000000000000000002505 120.0
DTH2_k127_7278052_5 Cysteine-rich domain - - - 0.00000000177 59.0
DTH2_k127_728020_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 7.942e-220 714.0
DTH2_k127_728020_1 response regulator K07689 - - 0.00000000000000000000000000000000000000000000000000000000000005362 220.0
DTH2_k127_728020_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000002268 155.0
DTH2_k127_729954_0 Belongs to the UPF0061 (SELO) family K08997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 608.0
DTH2_k127_729954_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070041,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 349.0
DTH2_k127_729954_2 metal-dependent phosphoesterases (PHP family) K07053 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 330.0
DTH2_k127_729954_3 - - - - 0.00000008862 59.0
DTH2_k127_7307673_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 486.0
DTH2_k127_7307673_1 alpha, beta K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002053 270.0
DTH2_k127_738924_0 Belongs to the thiolase family - - - 2.527e-202 636.0
DTH2_k127_738924_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.149e-201 641.0
DTH2_k127_738924_2 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 552.0
DTH2_k127_738924_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 334.0
DTH2_k127_738924_4 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 301.0
DTH2_k127_738924_5 transcriptional regulator - - - 0.0000000000000000000000000000000008945 137.0
DTH2_k127_7406443_1 Protein tyrosine kinase - - - 0.0006514 49.0
DTH2_k127_7435424_0 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
DTH2_k127_7435424_1 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 372.0
DTH2_k127_7435424_2 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 295.0
DTH2_k127_7455348_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 462.0
DTH2_k127_7455348_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 403.0
DTH2_k127_7455348_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 311.0
DTH2_k127_7455348_3 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000003048 217.0
DTH2_k127_7455348_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000001408 190.0
DTH2_k127_7455348_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000008942 181.0
DTH2_k127_7455348_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000014 143.0
DTH2_k127_7455348_7 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000003564 109.0
DTH2_k127_7455348_8 lipoprotein K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000002088 55.0
DTH2_k127_7455791_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 402.0
DTH2_k127_7455791_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 331.0
DTH2_k127_7455791_2 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.00000000000000000000000000000000000000000000000000008639 201.0
DTH2_k127_7455791_3 MazG-like family - - - 0.0000000000000000000000000000000000001738 148.0
DTH2_k127_7455791_4 ArsR family transcriptional regulator - - - 0.00000000000000000000000000001254 120.0
DTH2_k127_7455791_5 Tryptophan-rich protein (DUF2389) - - - 0.000000000000000000000001493 104.0
DTH2_k127_7455791_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002437 108.0
DTH2_k127_7455791_7 Protein of unknown function (DUF3617) - - - 0.000009471 55.0
DTH2_k127_7463289_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 540.0
DTH2_k127_7463289_1 transporter, permease K02033,K15581 - - 0.00000000000000000000000000000000000000000001382 166.0
DTH2_k127_7517065_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 391.0
DTH2_k127_7517065_1 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004561 265.0
DTH2_k127_7517065_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004786 261.0
DTH2_k127_7517065_3 phosphatase K01083,K07004 - 3.1.3.8 0.0000000000000000000000000000000000000000000000000000007422 208.0
DTH2_k127_7539678_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 365.0
DTH2_k127_7539678_1 PFAM Type II IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 341.0
DTH2_k127_7539678_2 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 273.0
DTH2_k127_7539678_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000044 173.0
DTH2_k127_7539678_4 protein conserved in bacteria K07028 - - 0.0004252 49.0
DTH2_k127_7545000_0 amine dehydrogenase activity - - - 8.945e-240 764.0
DTH2_k127_7545000_1 Protease prsW family - - - 0.00000000000000000000000000000000000000001133 166.0
DTH2_k127_7545000_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.000000000000000000000000000000000002587 140.0
DTH2_k127_7551599_0 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 571.0
DTH2_k127_7551599_1 Male sterility protein K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 541.0
DTH2_k127_7551599_2 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 482.0
DTH2_k127_7551599_3 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 450.0
DTH2_k127_7551599_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002835 258.0
DTH2_k127_7551599_5 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000000007505 157.0
DTH2_k127_7551599_6 PKD domain - - - 0.00000000000000000001192 108.0
DTH2_k127_7611108_0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 512.0
DTH2_k127_7611108_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 504.0
DTH2_k127_7611108_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 482.0
DTH2_k127_7611108_3 Polysaccharide biosynthesis protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 267.0
DTH2_k127_7611896_0 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 529.0
DTH2_k127_7611896_1 esterase lipase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 355.0
DTH2_k127_7611896_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005385,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006829,GO:0006873,GO:0006875,GO:0006876,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015086,GO:0015093,GO:0015291,GO:0015318,GO:0015341,GO:0015562,GO:0015684,GO:0015691,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0034755,GO:0042592,GO:0042802,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055073,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070574,GO:0070838,GO:0071577,GO:0071944,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1903874 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 309.0
DTH2_k127_7611896_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000009803 183.0
DTH2_k127_7611896_4 Tetratricopeptide repeat - - - 0.0000000000000982 72.0
DTH2_k127_7615510_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 422.0
DTH2_k127_7615510_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K14159 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 299.0
DTH2_k127_7615510_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000003955 213.0
DTH2_k127_7676076_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.085e-208 655.0
DTH2_k127_7676076_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 334.0
DTH2_k127_7676076_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 325.0
DTH2_k127_7676076_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 304.0
DTH2_k127_7676076_5 - - - - 0.00000006263 54.0
DTH2_k127_7676076_6 - - - - 0.0000006516 51.0
DTH2_k127_7694449_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.661e-207 654.0
DTH2_k127_7694449_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 359.0
DTH2_k127_7694449_2 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000004141 179.0
DTH2_k127_7712167_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002665 284.0
DTH2_k127_7712167_1 helicase K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000001614 239.0
DTH2_k127_7712167_2 AAA domain K07028 - - 0.0000000000000000000000000000000001862 138.0
DTH2_k127_7725982_0 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 4.446e-276 867.0
DTH2_k127_7725982_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 8.411e-195 621.0
DTH2_k127_7725982_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 582.0
DTH2_k127_7725982_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 286.0
DTH2_k127_7725982_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000003309 202.0
DTH2_k127_7725982_5 Protein of unknown function (DUF3426) - - - 0.00000000000000000000001327 106.0
DTH2_k127_7725982_6 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000003851 83.0
DTH2_k127_7726845_0 Multidrug MFS transporter - - - 1.256e-211 671.0
DTH2_k127_7726845_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 345.0
DTH2_k127_7726845_2 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
DTH2_k127_7726845_3 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.0000000000000000000000000000000000000000000000000000000000293 211.0
DTH2_k127_7726845_4 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.000000000000000000000000000000000000001729 150.0
DTH2_k127_7726845_5 cytochrome - - - 0.00000000000000000000000000000001001 130.0
DTH2_k127_7726845_6 Cytochrome c - - - 0.0000000000000000000000000761 111.0
DTH2_k127_7736836_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 423.0
DTH2_k127_7736836_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 347.0
DTH2_k127_7736836_2 Protein of unknown function (DUF2813) K07459 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 332.0
DTH2_k127_7736836_3 HlyD family secretion protein K01993 - - 0.00000000000009496 72.0
DTH2_k127_7768213_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 2.689e-256 802.0
DTH2_k127_7768213_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 507.0
DTH2_k127_7768213_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 326.0
DTH2_k127_7768213_3 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003913 248.0
DTH2_k127_7768213_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000001017 209.0
DTH2_k127_7768213_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000002466 204.0
DTH2_k127_7768213_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000008455 145.0
DTH2_k127_7768213_7 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000002946 138.0
DTH2_k127_7768213_8 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000001286 128.0
DTH2_k127_7768213_9 Regulatory protein, FmdB family - - - 0.000000000000000000000000000000638 124.0
DTH2_k127_7777813_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 603.0
DTH2_k127_7777813_1 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000603 260.0
DTH2_k127_7777813_2 TraB family K09973 - - 0.0000000000000000000000000000000000000000003342 169.0
DTH2_k127_7782784_0 E COG0620 Methionine synthase II (cobalamin-independent) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 582.0
DTH2_k127_7782784_1 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 321.0
DTH2_k127_7782784_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000006727 239.0
DTH2_k127_7782784_3 Ester cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000004411 227.0
DTH2_k127_7782784_4 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000001175 229.0
DTH2_k127_7830156_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.0 1253.0
DTH2_k127_7830156_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 430.0
DTH2_k127_7830156_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 370.0
DTH2_k127_7830156_3 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 368.0
DTH2_k127_7830156_4 cell division K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000123 280.0
DTH2_k127_7830156_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000007986 216.0
DTH2_k127_784240_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 445.0
DTH2_k127_784240_1 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000005802 195.0
DTH2_k127_784240_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000897 165.0
DTH2_k127_784240_3 TIGRFAM SUF system FeS K04488 - - 0.0000001054 54.0
DTH2_k127_7864377_0 TonB dependent receptor K02014 - - 1.714e-249 790.0
DTH2_k127_7864377_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 457.0
DTH2_k127_7864377_2 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 327.0
DTH2_k127_7864377_3 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 279.0
DTH2_k127_7864377_4 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
DTH2_k127_7864377_5 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001694 246.0
DTH2_k127_7864377_6 PFAM short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006015 239.0
DTH2_k127_7864377_7 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000000000499 222.0
DTH2_k127_7871295_0 TonB dependent receptor - - - 4.096e-282 887.0
DTH2_k127_7871295_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 439.0
DTH2_k127_7894365_0 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002532 270.0
DTH2_k127_7894365_1 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000000008277 220.0
DTH2_k127_7894365_2 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000002162 101.0
DTH2_k127_7899738_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 421.0
DTH2_k127_7899738_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 369.0
DTH2_k127_7899738_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 359.0
DTH2_k127_7899738_3 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
DTH2_k127_7899738_4 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 280.0
DTH2_k127_7899738_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000002188 241.0
DTH2_k127_7899738_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000009934 131.0
DTH2_k127_7899738_7 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000001022 61.0
DTH2_k127_7900617_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.635e-222 693.0
DTH2_k127_7900617_1 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 379.0
DTH2_k127_7900617_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 350.0
DTH2_k127_7900617_3 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002583 275.0
DTH2_k127_7900617_4 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000000000000005621 179.0
DTH2_k127_7900617_5 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000009042 173.0
DTH2_k127_7900617_6 - - - - 0.000000000000000000000000005161 114.0
DTH2_k127_791221_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.035e-203 640.0
DTH2_k127_791221_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000002454 281.0
DTH2_k127_7920100_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.98e-212 668.0
DTH2_k127_7920100_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 411.0
DTH2_k127_7920100_2 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000009168 205.0
DTH2_k127_7920100_3 PFAM Colicin V production protein K03558 - - 0.0000000000000000000000000000000000002029 148.0
DTH2_k127_7920100_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000004443 104.0
DTH2_k127_7920100_5 protein conserved in bacteria - - - 0.0000000000000000168 94.0
DTH2_k127_7985083_0 COG0668 Small-conductance mechanosensitive channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000007156 229.0
DTH2_k127_7985083_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000873 173.0
DTH2_k127_7985083_2 Histidine Phosphotransfer domain K02488,K11443 - 2.7.7.65 0.000000000000000000000000000000275 132.0
DTH2_k127_7985083_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000282 119.0
DTH2_k127_8008536_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 313.0
DTH2_k127_8008536_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000003191 215.0
DTH2_k127_8008536_2 Amino-transferase class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000001591 214.0
DTH2_k127_8008536_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000001111 160.0
DTH2_k127_8008560_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.513e-248 784.0
DTH2_k127_8008560_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000002266 173.0
DTH2_k127_8008560_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000003716 180.0
DTH2_k127_8008560_3 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.000000000000000000000000004887 113.0
DTH2_k127_8031713_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 6.312e-214 671.0
DTH2_k127_8031713_1 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 429.0
DTH2_k127_8031713_2 Mg2 and Co2 transporter CorC K06189 GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 305.0
DTH2_k127_8031713_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003667 260.0
DTH2_k127_8031713_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000004308 240.0
DTH2_k127_8031713_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000319 166.0
DTH2_k127_8031713_6 Domain of unknown function (DUF4105) - - - 0.000001436 53.0
DTH2_k127_804161_0 glutamate--cysteine ligase K01919 - 6.3.2.2 2.708e-220 691.0
DTH2_k127_804161_1 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 576.0
DTH2_k127_804161_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000001314 228.0
DTH2_k127_804161_3 ABC transporter substrate-binding protein K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000001803 78.0
DTH2_k127_8042241_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 5.437e-225 706.0
DTH2_k127_8042241_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 577.0
DTH2_k127_8042241_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 533.0
DTH2_k127_8042241_3 Transcriptional regulator K03719 GO:0000976,GO:0001067,GO:0001101,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009078,GO:0009080,GO:0009081,GO:0009082,GO:0009098,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016053,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046394,GO:0046395,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901698,GO:1901700,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000006344 156.0
DTH2_k127_8042241_4 MAPEG family - - - 0.0000000000000000000000000001959 118.0
DTH2_k127_8054498_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 469.0
DTH2_k127_8054498_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 394.0
DTH2_k127_8054498_10 Thioredoxin - - - 0.000000000000005759 76.0
DTH2_k127_8054498_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 336.0
DTH2_k127_8054498_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009878 278.0
DTH2_k127_8054498_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000001166 220.0
DTH2_k127_8054498_5 Competence protein - - - 0.000000000000000000000000000000000000000000000000000000154 205.0
DTH2_k127_8054498_6 Preprotein translocase subunit TatD K03424 - - 0.000000000000000000000000000000000000000000000000002054 193.0
DTH2_k127_8054498_7 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000006221 188.0
DTH2_k127_8054498_8 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000001069 170.0
DTH2_k127_8054498_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000003254 103.0
DTH2_k127_8097110_0 Major Facilitator Superfamily - - - 1.032e-256 799.0
DTH2_k127_8097110_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 458.0
DTH2_k127_8097110_2 Mu transposase, C-terminal K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 320.0
DTH2_k127_8097110_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000729 44.0
DTH2_k127_8127761_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.492e-244 761.0
DTH2_k127_8127761_1 arsenite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 580.0
DTH2_k127_8127761_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 560.0
DTH2_k127_8127761_3 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000002622 260.0
DTH2_k127_8127761_4 Citrate transporter - - - 0.00000000000000000000000000000000000001201 147.0
DTH2_k127_81384_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 597.0
DTH2_k127_81384_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 472.0
DTH2_k127_81384_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000002258 198.0
DTH2_k127_8218978_0 TrkA-N domain K11745 - - 2.805e-202 648.0
DTH2_k127_8218978_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 421.0
DTH2_k127_8218978_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 387.0
DTH2_k127_8218978_3 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 363.0
DTH2_k127_8218978_4 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 345.0
DTH2_k127_8218978_5 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000001109 113.0
DTH2_k127_8237920_0 Transcriptional regulatory protein, C terminal K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 310.0
DTH2_k127_8237920_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001996 291.0
DTH2_k127_8237920_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000002877 61.0
DTH2_k127_8278886_0 TraB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 435.0
DTH2_k127_8278886_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 396.0
DTH2_k127_8278886_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000005937 114.0
DTH2_k127_8278886_3 - - - - 0.0000000000005001 74.0
DTH2_k127_8278886_4 nuclear chromosome segregation - - - 0.0006003 48.0
DTH2_k127_8295876_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 617.0
DTH2_k127_8295876_1 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000000000000001553 169.0
DTH2_k127_8295876_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000019 139.0
DTH2_k127_8304543_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
DTH2_k127_8304543_1 adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003124 256.0
DTH2_k127_8304543_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.0000000000000000000000000000000000000000000003007 169.0
DTH2_k127_8304543_3 MAPEG family - - - 0.000000000000000000000000000002621 126.0
DTH2_k127_8304543_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000001658 79.0
DTH2_k127_8319127_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 608.0
DTH2_k127_8319127_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 409.0
DTH2_k127_8319127_2 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 406.0
DTH2_k127_8319127_3 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000002198 208.0
DTH2_k127_8320646_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1624.0
DTH2_k127_8320646_1 COG0608 Single-stranded DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 480.0
DTH2_k127_8320646_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000002785 218.0
DTH2_k127_8320646_3 carbamoyl-phosphate synthetase glutamine chain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000005888 205.0
DTH2_k127_8357195_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 531.0
DTH2_k127_8357195_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 396.0
DTH2_k127_8357195_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000006344 109.0
DTH2_k127_8357195_3 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000001128 107.0
DTH2_k127_8366060_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 414.0
DTH2_k127_8366060_1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000003909 235.0
DTH2_k127_8366060_2 PFAM Peptidase M20 K12941 - - 0.000000000000000000000000000000000000000000000000000004487 195.0
DTH2_k127_8366060_3 - - - - 0.000000000000000000000000000000000000000000000000003151 194.0
DTH2_k127_8366060_4 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.0000000000000000000000000001978 120.0
DTH2_k127_8374291_0 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 306.0
DTH2_k127_8374291_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000002229 236.0
DTH2_k127_8374291_2 protein, YerC YecD - - - 0.000000000000000000000002342 106.0
DTH2_k127_8398142_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.63e-309 959.0
DTH2_k127_8398142_1 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000003198 145.0
DTH2_k127_8417581_0 HEAT repeats - - - 0.000000000000000000000000000000000000000404 161.0
DTH2_k127_8417581_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000001545 153.0
DTH2_k127_8417581_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000127 122.0
DTH2_k127_8417581_3 - - - - 0.000000000000003681 85.0
DTH2_k127_8421688_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 2.946e-248 779.0
DTH2_k127_8421688_1 COG2939 Carboxypeptidase C (cathepsin A) - - - 1.329e-228 719.0
DTH2_k127_8421688_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 362.0
DTH2_k127_8421688_3 impB/mucB/samB family K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 324.0
DTH2_k127_8468788_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.101e-217 692.0
DTH2_k127_8468788_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 321.0
DTH2_k127_8468788_2 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 307.0
DTH2_k127_8468788_3 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000002295 246.0
DTH2_k127_8468788_4 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000006682 129.0
DTH2_k127_8494998_0 Putative methyltransferase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 444.0
DTH2_k127_8494998_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
DTH2_k127_8494998_2 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000000000000000000000000003614 217.0
DTH2_k127_8494998_3 Protein of unknown function (DUF2878) - - - 0.0000000000000000000000000000000000000000002681 165.0
DTH2_k127_850747_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.485e-248 785.0
DTH2_k127_850747_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 332.0
DTH2_k127_850747_2 Type I phosphodiesterase / nucleotide pyrophosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004204 289.0
DTH2_k127_850747_3 - - - - 0.00000000000000000000000000000008691 137.0
DTH2_k127_8522596_0 succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.0 1075.0
DTH2_k127_8522596_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 508.0
DTH2_k127_8522596_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 469.0
DTH2_k127_8522596_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 390.0
DTH2_k127_8522596_4 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005531 267.0
DTH2_k127_8522596_5 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001541 250.0
DTH2_k127_8522596_6 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006009 243.0
DTH2_k127_8522596_7 Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin K04085 - - 0.000000000000000000000000000001251 122.0
DTH2_k127_8522596_8 - - - - 0.00000000000007372 71.0
DTH2_k127_8522596_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000006247 66.0
DTH2_k127_8563368_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 591.0
DTH2_k127_8563368_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 560.0
DTH2_k127_8563368_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 407.0
DTH2_k127_8563368_3 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000036 256.0
DTH2_k127_8563368_4 Aminoglycoside phosphotransferase - - - 0.00000000000000000000906 93.0
DTH2_k127_8566984_0 Belongs to the glycosyl hydrolase 43 family K01198,K01209 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0046556,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.37,3.2.1.55 5.513e-243 763.0
DTH2_k127_8566984_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 507.0
DTH2_k127_8566984_2 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 404.0
DTH2_k127_8566984_3 bleomycin resistance protein - - - 0.0000000000000000000000000000000000000000001823 162.0
DTH2_k127_8590921_0 Type VI secretion K11891 - - 3.667e-282 906.0
DTH2_k127_8590921_1 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.00000000000000000000000000000000000000006948 161.0
DTH2_k127_8590921_2 Type VI secretion system protein DotU K11892 - - 0.00000000000000000000000000000368 123.0
DTH2_k127_8590921_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K11890,K20074 - 3.1.3.16 0.000000000000000000004283 96.0
DTH2_k127_8592312_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 520.0
DTH2_k127_8597501_0 Respiratory nitrate reductase alpha N-terminal K00370 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1394.0
DTH2_k127_8597501_1 Major Facilitator Superfamily K02575 - - 2.15e-280 868.0
DTH2_k127_8597501_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000002497 70.0
DTH2_k127_8619263_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 586.0
DTH2_k127_8619263_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 589.0
DTH2_k127_862606_0 Aldehyde dehydrogenase family K00154 - 1.2.1.68 2.997e-194 618.0
DTH2_k127_862606_1 serine threonine protein phosphatase K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000002502 217.0
DTH2_k127_862606_2 - - - - 0.00000004816 58.0
DTH2_k127_862606_3 CHAT domain - - - 0.000000096 66.0
DTH2_k127_862606_4 von Willebrand factor type A domain - - - 0.00003164 55.0
DTH2_k127_862606_5 Protein conserved in bacteria - - - 0.0003189 51.0
DTH2_k127_8626794_0 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 6.527e-225 706.0
DTH2_k127_8626794_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 473.0
DTH2_k127_8626794_2 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 303.0
DTH2_k127_8626794_3 membrane protein, hemolysin III homolog K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 282.0
DTH2_k127_8626794_4 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005451 240.0
DTH2_k127_8626794_5 Ribonuclease B OB domain - - - 0.0000000000000000000000000000001521 123.0
DTH2_k127_8662293_0 Cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 1.414e-289 898.0
DTH2_k127_8662293_1 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 318.0
DTH2_k127_874446_0 peptidase K01278 - 3.4.14.5 7.924e-319 994.0
DTH2_k127_874446_1 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 0.000000000000000000000000001393 119.0
DTH2_k127_8750162_0 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 441.0
DTH2_k127_8750162_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
DTH2_k127_8750162_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001161 279.0
DTH2_k127_8750162_3 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007167 278.0
DTH2_k127_8750162_4 Protein of unknown function (DUF3450) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006934 240.0
DTH2_k127_8750162_5 dihydrofolate reductase activity K00287,K18589 - 1.5.1.3 0.00000000000000000000000000000000000000000000000001407 186.0
DTH2_k127_8750162_6 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000001491 124.0
DTH2_k127_8751154_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 447.0
DTH2_k127_8751154_1 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 420.0
DTH2_k127_8751154_2 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000004585 254.0
DTH2_k127_8751154_3 Chromosome Partitioning - - - 0.000000000000000000000000000000000000000000000000000000006556 203.0
DTH2_k127_8751154_4 CYTH - - - 0.0000000000000000000000000006179 125.0
DTH2_k127_8751154_5 Helix-hairpin-helix domain - - - 0.000007344 53.0
DTH2_k127_8781531_0 PFAM Glycosyl transferase family 2 - - - 0.0 1126.0
DTH2_k127_8781531_1 PFAM Sulfatase - - - 2.595e-209 667.0
DTH2_k127_8781531_2 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.0000000000000003374 79.0
DTH2_k127_8796506_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000267 148.0
DTH2_k127_8796506_1 - - - - 0.000000000000000000000000000000003393 137.0
DTH2_k127_8815678_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 344.0
DTH2_k127_8815678_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 334.0
DTH2_k127_8815678_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 307.0
DTH2_k127_8815678_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 235.0
DTH2_k127_8815678_4 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000002984 188.0
DTH2_k127_8815678_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000005375 181.0
DTH2_k127_8832684_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 319.0
DTH2_k127_8832684_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 304.0
DTH2_k127_8832684_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 288.0
DTH2_k127_8832684_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000583 168.0
DTH2_k127_8832684_4 NnrU protein - - - 0.00000000000000000000000000000000000000000002417 168.0
DTH2_k127_8832684_5 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000001022 94.0
DTH2_k127_8854684_0 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 352.0
DTH2_k127_8854684_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 295.0
DTH2_k127_8854684_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000001574 195.0
DTH2_k127_8854684_3 GtrA-like protein - - - 0.000000000000000000000000000000000001264 143.0
DTH2_k127_8854684_4 Methyltransferase domain - - - 0.0000000000002853 82.0
DTH2_k127_8924230_0 ABC transporter permease K02037 - - 2.369e-219 703.0
DTH2_k127_8924230_1 Phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000001905 205.0
DTH2_k127_8924230_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000007237 184.0
DTH2_k127_8933297_0 Acetyl-coenzyme A synthetase N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 570.0
DTH2_k127_8933297_1 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 370.0
DTH2_k127_8933297_2 electron transfer flavoprotein beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 346.0
DTH2_k127_8933297_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000002011 143.0
DTH2_k127_8933911_0 protein conserved in bacteria K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 567.0
DTH2_k127_8933911_1 ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 465.0
DTH2_k127_8933911_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 382.0
DTH2_k127_8933911_3 Proline racemase - GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0050346 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 336.0
DTH2_k127_8933911_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000007442 171.0
DTH2_k127_8933911_5 Antibiotic biosynthesis monooxygenase K06996 - - 0.000000000000000000000000000000000000000002846 158.0
DTH2_k127_8933911_6 - - - - 0.000000000000000000000000000000000004008 143.0
DTH2_k127_8964733_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1172.0
DTH2_k127_8968519_0 Nitrate reductase beta subunit K00371 - 1.7.5.1 3.67e-276 858.0
DTH2_k127_8968519_1 the beta subunit is an iron sulfur cluster containing electron transfer subunit K00370 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 464.0
DTH2_k127_8968519_2 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000000000000000001311 210.0
DTH2_k127_8968519_3 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000002587 123.0
DTH2_k127_8984217_0 Bacterial virulence factor lipase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 426.0
DTH2_k127_8984217_1 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
DTH2_k127_9001752_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 597.0
DTH2_k127_9001752_1 Nitrilase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 463.0
DTH2_k127_9001752_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 443.0
DTH2_k127_9011619_0 5'-nucleotidase, C-terminal domain K17224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 365.0
DTH2_k127_9011619_1 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 338.0
DTH2_k127_9011619_2 C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells K17222,K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 337.0
DTH2_k127_9011619_3 Sulfur oxidation protein SoxY - - - 0.0000000000000000000000000000000000001795 146.0
DTH2_k127_9011619_4 Cytochrome c K17223 - - 0.00000000000000000000000000000003703 128.0
DTH2_k127_9011619_5 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000002156 123.0
DTH2_k127_9011619_6 - - - - 0.0004488 47.0
DTH2_k127_901194_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 432.0
DTH2_k127_901194_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 354.0
DTH2_k127_901194_2 catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
DTH2_k127_9023982_0 4Fe-4S dicluster domain - - - 8.264e-266 824.0
DTH2_k127_9023982_1 Sulfite reductase K11181 - 1.8.99.5 4.514e-208 650.0
DTH2_k127_9023982_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 612.0
DTH2_k127_9023982_3 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 358.0
DTH2_k127_9023982_4 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002054 276.0
DTH2_k127_9023982_5 TIGRFAM sulfur relay protein TusD DsrE K07235 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - 0.000000000000000000000000000000000000000000000000000002148 194.0
DTH2_k127_9023982_6 Belongs to the DsrF TusC family K07236 - - 0.0000000000000000000000000000000000000000000000000001678 187.0
DTH2_k127_9023982_7 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000006611 179.0
DTH2_k127_9023982_8 sulfur relay protein TusB DsrH K07237 - - 0.0000000000000000000000000000000002254 134.0
DTH2_k127_9028243_0 Extracellular nuclease K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002743 292.0
DTH2_k127_9028243_1 Alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000594 276.0
DTH2_k127_9028243_2 Acyl carrier protein phosphodiesterase - - - 0.000000000000000000000000000000000006156 143.0
DTH2_k127_9028243_3 Reduces the stability of FtsZ polymers in the presence of ATP K06916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - 0.00000000000000000000000001745 114.0
DTH2_k127_9039583_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 392.0
DTH2_k127_9039583_1 protein conserved in bacteria containing a pentein-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
DTH2_k127_9039583_2 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000004004 237.0
DTH2_k127_9039583_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000009728 111.0
DTH2_k127_9039583_4 PFAM Response regulator receiver domain K07660 - - 0.0000000000000000000000132 102.0
DTH2_k127_9039583_5 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000003708 81.0
DTH2_k127_9039583_6 - - - - 0.0005464 46.0
DTH2_k127_9096531_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.444e-244 773.0
DTH2_k127_9096531_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 6.848e-234 743.0
DTH2_k127_9096531_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 306.0
DTH2_k127_9096531_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002495 282.0
DTH2_k127_9096531_4 stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001576 246.0
DTH2_k127_9096531_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000003203 229.0
DTH2_k127_9096531_6 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.0000000000000000000000000000000000000000000000002109 180.0
DTH2_k127_9096531_7 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000001921 173.0
DTH2_k127_9096531_8 - - - - 0.00000000000000000000000000001872 123.0
DTH2_k127_9096531_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000007041 104.0
DTH2_k127_9096609_0 serine-type peptidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 390.0
DTH2_k127_9096609_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000001667 221.0
DTH2_k127_9096609_2 Alpha/beta hydrolase family - - - 0.0000000000000000000003648 101.0
DTH2_k127_9128950_0 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 424.0
DTH2_k127_9128950_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008302 301.0
DTH2_k127_9128950_2 MerR HTH family regulatory protein K18997 - - 0.00000000000000000000009232 101.0
DTH2_k127_9132788_0 Beta-eliminating lyase K01667 - 4.1.99.1 3.049e-208 657.0
DTH2_k127_9132788_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 583.0
DTH2_k127_9132788_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 562.0
DTH2_k127_9132788_3 COG3547 Transposase and inactivated derivatives K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 467.0
DTH2_k127_9132788_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 422.0
DTH2_k127_9132788_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006678 278.0
DTH2_k127_9132792_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 6.648e-210 659.0
DTH2_k127_9132792_1 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 287.0
DTH2_k127_9132792_2 Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle K00564 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 0.000000000000000000000000000000000000000000000000000008625 202.0
DTH2_k127_9132792_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000417 135.0
DTH2_k127_9132792_4 PDZ domain - - - 0.0000000000000000000001066 112.0
DTH2_k127_9132792_5 Belongs to the SOS response-associated peptidase family - - - 0.000000000000002559 85.0
DTH2_k127_9137741_0 COG1960 Acyl-CoA dehydrogenases K06445 - - 4.902e-265 841.0
DTH2_k127_9137741_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 364.0
DTH2_k127_9137741_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000002709 224.0
DTH2_k127_9137741_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000001355 188.0
DTH2_k127_9145629_0 transferase activity, transferring glycosyl groups K13657 - 2.4.1.252 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 329.0
DTH2_k127_9145629_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004309 276.0
DTH2_k127_9145629_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004705 274.0
DTH2_k127_9145629_3 SMART AAA ATPase K02450 - - 0.000000000000000000000000002913 123.0
DTH2_k127_9145629_4 CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000003087 106.0
DTH2_k127_9223037_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 4.054e-262 822.0
DTH2_k127_9223037_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 506.0
DTH2_k127_9223037_2 Fe-S protein K06938 - - 0.00000000000001589 76.0
DTH2_k127_9264311_0 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009192 264.0
DTH2_k127_9264311_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001108 239.0
DTH2_k127_9264311_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000005013 83.0
DTH2_k127_9264311_3 helix_turn_helix, Lux Regulon K20264 - - 0.000000000005747 72.0
DTH2_k127_9268612_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 541.0
DTH2_k127_9268612_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 462.0
DTH2_k127_9268612_10 PFAM Transposase, IS4-like - - - 0.00000000000000001564 85.0
DTH2_k127_9268612_11 Phage shock protein B K03970 - - 0.000000000001163 69.0
DTH2_k127_9268612_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 371.0
DTH2_k127_9268612_3 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002291 271.0
DTH2_k127_9268612_4 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 265.0
DTH2_k127_9268612_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 251.0
DTH2_k127_9268612_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000008958 244.0
DTH2_k127_9268612_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000009451 226.0
DTH2_k127_9268612_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000008055 201.0
DTH2_k127_9268612_9 PspC domain K03973 - - 0.000000000000000000000000000000002216 134.0
DTH2_k127_9283998_0 O-acetylhomoserine K01740 - 2.5.1.49 2.39e-206 648.0
DTH2_k127_9283998_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 531.0
DTH2_k127_9283998_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 - 2.3.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 470.0
DTH2_k127_9283998_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000002769 212.0
DTH2_k127_9298886_0 COG NOG08360 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 574.0
DTH2_k127_9298886_1 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 331.0
DTH2_k127_9327712_0 Peptidase family M13 K01415,K07386 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000002897 271.0
DTH2_k127_9327712_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000007604 230.0
DTH2_k127_9327712_2 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000002002 216.0
DTH2_k127_9327712_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000001781 189.0
DTH2_k127_9327712_4 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000000000000000000001226 184.0
DTH2_k127_9327778_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 2.642e-223 713.0
DTH2_k127_9327778_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 567.0
DTH2_k127_9327778_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 353.0
DTH2_k127_9327778_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 301.0
DTH2_k127_9327778_4 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000001716 160.0
DTH2_k127_9327778_5 acyl-coa dehydrogenase K09456 - - 0.00000000000000000009917 90.0
DTH2_k127_9327778_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000001418 89.0
DTH2_k127_9345856_0 Pyruvate kinase K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 474.0
DTH2_k127_9345856_1 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000008837 214.0
DTH2_k127_9345856_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000007862 181.0
DTH2_k127_9345856_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000000000000000000003371 123.0
DTH2_k127_9373120_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 5.113e-313 980.0
DTH2_k127_9373120_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 5.207e-297 919.0
DTH2_k127_9373120_2 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 411.0
DTH2_k127_9373120_3 FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001569 277.0
DTH2_k127_9373120_4 Iron-storage protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000072 251.0
DTH2_k127_9373120_5 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001092 237.0
DTH2_k127_9373120_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000002895 208.0
DTH2_k127_9373120_7 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000002174 172.0
DTH2_k127_9373120_8 - - - - 0.0000000000000000000000000000000000005639 148.0
DTH2_k127_9373120_9 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000000003525 77.0
DTH2_k127_9412085_0 Transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 500.0
DTH2_k127_9412085_1 PFAM nucleoside recognition domain protein K06373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001619 266.0
DTH2_k127_9412085_2 PFAM nucleoside recognition domain protein K06374 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
DTH2_k127_9412085_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000001373 207.0
DTH2_k127_9427408_0 transport system involved in gliding motility, auxiliary component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 533.0
DTH2_k127_9427408_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
DTH2_k127_9427408_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 344.0
DTH2_k127_9427408_3 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 344.0
DTH2_k127_9427408_4 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000002929 126.0
DTH2_k127_9427408_5 - - - - 0.0001545 47.0
DTH2_k127_9456902_0 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002692 282.0
DTH2_k127_9456902_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
DTH2_k127_9456902_2 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
DTH2_k127_9456902_3 FeS assembly protein SufB K09014 - - 0.00000000000000000000000000000000000000000000000000000000001333 209.0
DTH2_k127_9456902_4 transcriptional regulator - - - 0.00000000000000000000000000000000009921 138.0
DTH2_k127_9458234_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 578.0
DTH2_k127_9458234_1 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000001474 213.0
DTH2_k127_9476691_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.79e-279 870.0
DTH2_k127_9476691_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 413.0
DTH2_k127_9476691_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 349.0
DTH2_k127_9476691_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 262.0
DTH2_k127_9476691_4 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000002806 237.0
DTH2_k127_9476691_5 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase - - - 0.00000000000000000000000000000000000000000001233 175.0
DTH2_k127_9476691_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000002643 154.0
DTH2_k127_950660_0 response regulator K02481 - - 1.419e-212 670.0
DTH2_k127_950660_1 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 530.0
DTH2_k127_950660_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 436.0
DTH2_k127_950660_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000005791 139.0
DTH2_k127_950660_4 Planctomycete cytochrome C - - - 0.0000000000000000000000000000005923 130.0
DTH2_k127_950660_5 - - - - 0.00000000006576 63.0
DTH2_k127_9530092_0 Belongs to the aspartokinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 596.0
DTH2_k127_9533629_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.658e-200 634.0
DTH2_k127_9533629_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 333.0
DTH2_k127_9533629_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 304.0
DTH2_k127_9533629_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 283.0
DTH2_k127_9533629_4 SCP-2 sterol transfer family K03690 - - 0.00000000000000000001201 98.0
DTH2_k127_9533629_5 - - - - 0.000000122 59.0
DTH2_k127_953669_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000004898 166.0
DTH2_k127_953669_1 type IV pilus modification protein PilV K02671 - - 0.0000000000000000002444 94.0
DTH2_k127_953669_2 Type IV minor pilin ComP, DNA uptake sequence receptor - - - 0.000000000000215 79.0
DTH2_k127_953669_3 Type IV pilus assembly protein PilX C-term K02673 - - 0.00000002885 64.0
DTH2_k127_953669_4 Type IV Pilus-assembly protein W - - - 0.000003031 58.0
DTH2_k127_953669_5 - - - - 0.0004391 44.0
DTH2_k127_9583693_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 585.0
DTH2_k127_9583693_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 509.0
DTH2_k127_9583693_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 345.0
DTH2_k127_9583693_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000458 199.0
DTH2_k127_9583693_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000001946 189.0
DTH2_k127_9583693_5 enoyl-CoA hydratase isomerase K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000698 124.0
DTH2_k127_9586846_0 AMP-binding enzyme C-terminal domain K00666 - - 1.213e-201 640.0
DTH2_k127_9586846_1 MaoC like domain - - - 0.0000000000000000000001827 99.0
DTH2_k127_9586846_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000002052 55.0
DTH2_k127_9595082_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 445.0
DTH2_k127_9595082_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 288.0
DTH2_k127_9595082_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003452 274.0
DTH2_k127_9595082_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000003993 187.0
DTH2_k127_9608635_0 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 515.0
DTH2_k127_9608635_1 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 332.0
DTH2_k127_9608635_2 Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol K03184,K18800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 327.0
DTH2_k127_9608635_3 Belongs to the UPF0149 family K09895 - - 0.0000000000000000000003424 104.0
DTH2_k127_9608635_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000001246 83.0
DTH2_k127_9608635_5 5-formyltetrahydrofolate cyclo-ligase family - - - 0.00000001038 62.0
DTH2_k127_9641961_0 Carboxypeptidase regulatory-like domain - - - 0.0 1021.0
DTH2_k127_9641961_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 448.0
DTH2_k127_9641961_2 COG3023 Negative regulator of beta-lactamase expression K01447,K03806,K11066 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 288.0
DTH2_k127_9641961_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000001502 204.0
DTH2_k127_9696469_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 391.0
DTH2_k127_9696469_1 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 296.0
DTH2_k127_9696469_2 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004036 286.0
DTH2_k127_9696469_3 Adenylate cyclase - - - 0.00006222 50.0
DTH2_k127_9717236_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 594.0
DTH2_k127_9717236_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 518.0
DTH2_k127_9717236_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 515.0
DTH2_k127_9717236_3 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 413.0
DTH2_k127_9717236_4 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
DTH2_k127_9717236_5 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000002355 252.0
DTH2_k127_9717236_6 glutamine amidotransferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000005707 218.0
DTH2_k127_9717236_7 of membrane protease K07340 - - 0.000000000000000000000000000000000000000000005796 168.0
DTH2_k127_9745317_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000105 296.0
DTH2_k127_9745317_1 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004141 244.0
DTH2_k127_9745317_2 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000005563 247.0
DTH2_k127_9745317_3 asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000004447 230.0
DTH2_k127_9745317_4 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000009863 223.0
DTH2_k127_9745317_5 Arsenate reductase and related K00537 - 1.20.4.1 0.000000000000000000000000000000000000001572 149.0
DTH2_k127_9760569_0 TonB dependent receptor - - - 1.896e-254 812.0
DTH2_k127_9760569_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375,K05825 - - 1.267e-200 642.0
DTH2_k127_9760569_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 347.0
DTH2_k127_9760569_3 ATPase involved in DNA repair - - - 0.000000001063 69.0
DTH2_k127_9804429_0 Amidohydrolase family - - - 4.106e-196 617.0
DTH2_k127_9804429_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 424.0
DTH2_k127_9804429_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 365.0
DTH2_k127_9804429_3 COG1668 ABC-type Na efflux pump, permease component K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 340.0
DTH2_k127_9804429_4 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 324.0
DTH2_k127_9804429_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000005152 193.0
DTH2_k127_9804429_6 Transport permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001255 55.0
DTH2_k127_9839408_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 287.0
DTH2_k127_9839408_1 chemotaxis, protein K02660 - - 0.000000000000000000000000000000000000000000000000000000002253 216.0
DTH2_k127_9839408_2 response regulator K02657 - - 0.00000000000000000000000000000000000000000000000000002461 191.0
DTH2_k127_9839408_3 chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000000000001323 139.0
DTH2_k127_9858358_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 585.0
DTH2_k127_9858358_1 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 540.0
DTH2_k127_9858358_2 PFAM YhhN-like protein - - - 0.00001996 51.0
DTH2_k127_9893855_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.138e-205 665.0
DTH2_k127_9893855_1 Dicarboxylate transport - - - 0.000000000000000000114 105.0
DTH2_k127_9901106_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 610.0
DTH2_k127_9901106_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 484.0
DTH2_k127_9901106_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 450.0
DTH2_k127_9901106_3 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 321.0
DTH2_k127_9901106_4 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000003425 211.0
DTH2_k127_9901106_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000001314 134.0
DTH2_k127_9901106_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000001866 97.0
DTH2_k127_9901106_7 Uncharacterized ACR, COG1399 K07040 - - 0.000000000001732 76.0
DTH2_k127_9901106_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 0.0000000003022 63.0
DTH2_k127_9910612_0 Domain of unknown function (DUF4445) - - - 4.555e-268 841.0
DTH2_k127_9910612_1 COG1410 Methionine synthase I cobalamin-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 428.0
DTH2_k127_9910612_2 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005266 233.0
DTH2_k127_9910612_3 B12 binding domain K00548 - 2.1.1.13 0.000000000000000008985 83.0