Overview

ID MAG00781
Name DTH2_bin.51
Sample SMP0023
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order 40CM-2-53-6
Family RBG-13-38-9
Genus JAPKYM01
Species
Assembly information
Completeness (%) 88.4
Contamination (%) 3.14
GC content (%) 47.0
N50 (bp) 11,435
Genome size (bp) 1,657,596

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1577

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10016566_0 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 325.0
DTH2_k127_10016566_1 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000008843 227.0
DTH2_k127_10016566_2 Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT( ) K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000005379 201.0
DTH2_k127_10016566_3 DNA polymerase beta domain protein region K09717 - - 0.00000000000000000000000000000000000000001848 166.0
DTH2_k127_10016566_4 F420-0:Gamma-glutamyl ligase - - - 0.0000000000000000000000000000000000000001135 162.0
DTH2_k127_1026701_0 - - - - 0.000000001887 70.0
DTH2_k127_1059570_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 385.0
DTH2_k127_1059570_1 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 375.0
DTH2_k127_1059570_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004653 285.0
DTH2_k127_1059570_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001058 243.0
DTH2_k127_1059570_4 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000004684 59.0
DTH2_k127_107764_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000001072 196.0
DTH2_k127_107764_1 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000007475 178.0
DTH2_k127_107764_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000109 177.0
DTH2_k127_107764_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000001893 111.0
DTH2_k127_107764_4 Ribonuclease III - - - 0.0000000000000000001225 94.0
DTH2_k127_1183426_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 381.0
DTH2_k127_1183426_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000538 212.0
DTH2_k127_1183426_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000007154 164.0
DTH2_k127_1183426_3 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000388 153.0
DTH2_k127_1183426_4 CoA binding domain K06929 - - 0.00000000000000000000000000000000002892 139.0
DTH2_k127_1183426_5 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000001546 101.0
DTH2_k127_1183426_6 PFAM CBS domain containing protein - - - 0.000000000000000000001198 100.0
DTH2_k127_1183426_7 COG NOG14600 non supervised orthologous group - - - 0.0000003592 53.0
DTH2_k127_120421_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 563.0
DTH2_k127_120421_1 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 525.0
DTH2_k127_120421_2 alcohol dehydrogenase K19954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 296.0
DTH2_k127_1208508_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 479.0
DTH2_k127_1208508_1 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000001262 186.0
DTH2_k127_1208508_2 PFAM type II secretion system K07333 - - 0.0000000000000000000000000000000000007423 150.0
DTH2_k127_1208508_3 Type II secretion system K07333 - - 0.0000000000000000000000000000000000639 146.0
DTH2_k127_1208508_4 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000003459 139.0
DTH2_k127_1208508_5 Winged helix-turn-helix - - - 0.00000000000000000000001784 115.0
DTH2_k127_1208508_6 PFAM glycosyl transferase family 39 - - - 0.000000004306 68.0
DTH2_k127_1208508_7 Radical SAM K22227 - - 0.000002199 53.0
DTH2_k127_1208508_8 PFAM glycosyl transferase family 39 - - - 0.00001669 57.0
DTH2_k127_1358094_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 538.0
DTH2_k127_1358094_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 453.0
DTH2_k127_1358094_10 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000003386 252.0
DTH2_k127_1358094_11 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000001004 246.0
DTH2_k127_1358094_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006386 225.0
DTH2_k127_1358094_13 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000008436 221.0
DTH2_k127_1358094_14 B3/4 domain - - - 0.0000000000000000000000000000000000000000000000000000000004727 209.0
DTH2_k127_1358094_15 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000007393 185.0
DTH2_k127_1358094_16 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000007213 180.0
DTH2_k127_1358094_17 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000001448 176.0
DTH2_k127_1358094_18 ABC transporter K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000001083 167.0
DTH2_k127_1358094_19 UbiA prenyltransferase family K02257 - 2.5.1.141 0.00000000000000000000000000000000000008299 153.0
DTH2_k127_1358094_2 heavy metal-(Cd Co Hg Pb Zn)-translocating K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 460.0
DTH2_k127_1358094_20 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000004927 125.0
DTH2_k127_1358094_21 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000002159 116.0
DTH2_k127_1358094_22 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.00000000000000000000000009086 115.0
DTH2_k127_1358094_23 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000001877 114.0
DTH2_k127_1358094_24 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000001255 114.0
DTH2_k127_1358094_25 Glycosyl transferase family 2 - - - 0.000000000000000001345 98.0
DTH2_k127_1358094_26 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000027 89.0
DTH2_k127_1358094_27 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000001263 77.0
DTH2_k127_1358094_28 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000006735 67.0
DTH2_k127_1358094_29 - - - - 0.00000009611 60.0
DTH2_k127_1358094_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 449.0
DTH2_k127_1358094_30 - - - - 0.000307 45.0
DTH2_k127_1358094_31 nitrate reductase activity - - - 0.0004725 51.0
DTH2_k127_1358094_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 371.0
DTH2_k127_1358094_5 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 356.0
DTH2_k127_1358094_6 Polysulphide reductase K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 313.0
DTH2_k127_1358094_7 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 317.0
DTH2_k127_1358094_8 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006851 280.0
DTH2_k127_1358094_9 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005698 262.0
DTH2_k127_1462610_0 aconitate hydratase K01681 - 4.2.1.3 3.099e-272 850.0
DTH2_k127_1462610_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 2.526e-265 831.0
DTH2_k127_1462610_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000001834 197.0
DTH2_k127_1462610_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000001101 164.0
DTH2_k127_1462610_4 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000006676 143.0
DTH2_k127_1462610_6 - - - - 0.0000000001795 66.0
DTH2_k127_1462610_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000003413 61.0
DTH2_k127_1462610_8 bacterioferritin K03594 - 1.16.3.1 0.0000001429 63.0
DTH2_k127_148676_0 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 319.0
DTH2_k127_148676_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000002549 160.0
DTH2_k127_148676_2 M6 family metalloprotease domain protein - - - 0.00000008112 64.0
DTH2_k127_148676_3 Peptidase C13 family - - - 0.000001238 59.0
DTH2_k127_148676_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00001405 51.0
DTH2_k127_1490301_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 604.0
DTH2_k127_1490301_1 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000002977 215.0
DTH2_k127_1490301_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000004739 92.0
DTH2_k127_1490301_3 haloacid dehalogenase-like hydrolase K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.00000000000000003367 91.0
DTH2_k127_1490301_4 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000004035 52.0
DTH2_k127_1506756_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 5.119e-195 617.0
DTH2_k127_1506756_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 553.0
DTH2_k127_1506756_2 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 410.0
DTH2_k127_1506756_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 395.0
DTH2_k127_1506756_4 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
DTH2_k127_1506756_5 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008314 286.0
DTH2_k127_1506756_6 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006342 254.0
DTH2_k127_1506756_7 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000002635 203.0
DTH2_k127_1506756_8 Peptidase family M48 - - - 0.00000000000000000000001034 112.0
DTH2_k127_1641640_0 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 414.0
DTH2_k127_1641640_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 338.0
DTH2_k127_1641640_10 Sugar (and other) transporter - - - 0.0000000000000000000008068 108.0
DTH2_k127_1641640_12 Domain of unknown function (DUF4389) - - - 0.000000000001581 76.0
DTH2_k127_1641640_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000003509 224.0
DTH2_k127_1641640_3 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000001212 218.0
DTH2_k127_1641640_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000001714 187.0
DTH2_k127_1641640_5 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000002937 184.0
DTH2_k127_1641640_6 Putative TM nitroreductase - - - 0.00000000000000000000000000000000002344 141.0
DTH2_k127_1641640_7 PFAM glutaredoxin - - - 0.000000000000000000000000000000003518 130.0
DTH2_k127_1641640_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000002952 131.0
DTH2_k127_1641640_9 Rhodanese Homology Domain - - - 0.000000000000000000000000007532 126.0
DTH2_k127_1691126_0 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 403.0
DTH2_k127_1691126_1 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 354.0
DTH2_k127_1691126_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009262 273.0
DTH2_k127_1691126_3 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000007684 194.0
DTH2_k127_1691126_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000003797 175.0
DTH2_k127_1691126_5 Cupin domain protein - - - 0.00000000000000000000000000000000000006111 145.0
DTH2_k127_1691126_6 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.0000000000000000000000000001136 119.0
DTH2_k127_1691126_7 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000003708 112.0
DTH2_k127_1692076_0 4Fe-4S dicluster domain K00196 - - 0.0000000000000000000000000000000000000000000000000002383 191.0
DTH2_k127_1692076_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000001523 69.0
DTH2_k127_1692076_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0004585 44.0
DTH2_k127_182146_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1656.0
DTH2_k127_182146_1 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 1.152e-275 864.0
DTH2_k127_182146_10 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000003845 139.0
DTH2_k127_182146_11 Belongs to the UPF0235 family K09131 - - 0.00000000000000000001223 93.0
DTH2_k127_182146_12 Domain of unknown function (DUF362) - - - 0.0000000000000000000182 103.0
DTH2_k127_182146_13 Copper-transporting ATPase K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0010035,GO:0010038,GO:0010273,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0046873,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061687,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0099131,GO:0099132,GO:1990169 3.6.3.54 0.000000005931 61.0
DTH2_k127_182146_14 CAAX protease self-immunity - - - 0.000000006667 63.0
DTH2_k127_182146_16 FMN binding - - - 0.00000007265 61.0
DTH2_k127_182146_17 - - - - 0.000003464 56.0
DTH2_k127_182146_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.771e-199 641.0
DTH2_k127_182146_3 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
DTH2_k127_182146_4 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 368.0
DTH2_k127_182146_5 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001003 289.0
DTH2_k127_182146_6 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001994 277.0
DTH2_k127_182146_7 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000001162 226.0
DTH2_k127_182146_8 Integral membrane protein DUF92 K00981,K18678 GO:0005575,GO:0016020 2.7.1.182,2.7.7.41 0.00000000000000000000000000000000000000006651 162.0
DTH2_k127_182146_9 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000001177 141.0
DTH2_k127_1962543_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1302.0
DTH2_k127_1962543_1 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1073.0
DTH2_k127_1962543_10 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000514 255.0
DTH2_k127_1962543_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001125 244.0
DTH2_k127_1962543_12 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000002303 177.0
DTH2_k127_1962543_13 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.0000000000000000000000000000000000000000000000216 176.0
DTH2_k127_1962543_14 MazG-like family - - - 0.0000000000000000000000001503 112.0
DTH2_k127_1962543_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000005591 112.0
DTH2_k127_1962543_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000005576 97.0
DTH2_k127_1962543_17 NUDIX domain - - - 0.000000000000000000002138 99.0
DTH2_k127_1962543_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000002729 74.0
DTH2_k127_1962543_19 Sulphur transport K07112 - - 0.00000000001543 76.0
DTH2_k127_1962543_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 8.029e-226 713.0
DTH2_k127_1962543_20 Prokaryotic homologs of the JAB domain K03030 - - 0.0000000003878 70.0
DTH2_k127_1962543_21 QueT transporter - - - 0.000000001067 66.0
DTH2_k127_1962543_22 Belongs to the sulfur carrier protein TusA family K07112 - - 0.00000000131 65.0
DTH2_k127_1962543_23 Belongs to the sulfur carrier protein TusA family - - - 0.000003735 52.0
DTH2_k127_1962543_24 Sodium hydrogen exchanger - - - 0.000005071 50.0
DTH2_k127_1962543_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 471.0
DTH2_k127_1962543_4 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 393.0
DTH2_k127_1962543_5 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 363.0
DTH2_k127_1962543_6 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 380.0
DTH2_k127_1962543_7 Protein of unknown function (DUF2961) K14109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 300.0
DTH2_k127_1962543_8 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 289.0
DTH2_k127_1962543_9 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001683 246.0
DTH2_k127_1983818_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 6.037e-268 842.0
DTH2_k127_1983818_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 342.0
DTH2_k127_1983818_10 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000001055 104.0
DTH2_k127_1983818_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000001939 79.0
DTH2_k127_1983818_12 Cytochrome c - - - 0.000000001789 66.0
DTH2_k127_1983818_13 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000002047 56.0
DTH2_k127_1983818_2 ABC-type cobalt transport system ATPase component K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003252 275.0
DTH2_k127_1983818_3 PFAM ABC transporter related K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001533 248.0
DTH2_k127_1983818_4 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000001836 223.0
DTH2_k127_1983818_5 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000002361 204.0
DTH2_k127_1983818_6 PFAM Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000003027 170.0
DTH2_k127_1983818_7 ERCC4 domain protein K10848 - - 0.000000000000000000000000000000001771 139.0
DTH2_k127_1983818_8 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000002183 135.0
DTH2_k127_1983818_9 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000005316 134.0
DTH2_k127_1983940_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 452.0
DTH2_k127_1983940_1 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000002152 110.0
DTH2_k127_1983940_2 PFAM Penicillinase repressor - - - 0.0000000000000002168 84.0
DTH2_k127_1983940_3 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000001562 77.0
DTH2_k127_1983940_4 BlaR1 peptidase M56 K02172 - - 0.00001039 56.0
DTH2_k127_2006772_0 TIGRFAM reductive dehalogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001537 250.0
DTH2_k127_2006772_1 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000000000002706 226.0
DTH2_k127_2006772_2 PFAM ABC transporter K02003,K02004 - - 0.000000000000000000000000000000000000006082 149.0
DTH2_k127_2006772_3 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000477 149.0
DTH2_k127_2006772_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000004442 149.0
DTH2_k127_2006772_5 DUF72 domain containing protein - - - 0.000000000000000000000005214 109.0
DTH2_k127_2006772_6 - - - - 0.0000000000000000003389 93.0
DTH2_k127_2006772_7 - - - - 0.00000000000000004703 85.0
DTH2_k127_2006772_8 PFAM Bacterial protein of - - - 0.000000000000003943 83.0
DTH2_k127_2021593_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 387.0
DTH2_k127_2021593_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 350.0
DTH2_k127_2021593_2 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 292.0
DTH2_k127_2021593_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000009859 248.0
DTH2_k127_2021593_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000001272 221.0
DTH2_k127_2021593_5 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000005751 199.0
DTH2_k127_2021593_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000001119 140.0
DTH2_k127_2021593_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000002671 109.0
DTH2_k127_2021593_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000004181 98.0
DTH2_k127_2021593_9 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000003271 89.0
DTH2_k127_2023415_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 449.0
DTH2_k127_2054480_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 304.0
DTH2_k127_2054480_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 296.0
DTH2_k127_2054480_2 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001148 249.0
DTH2_k127_2054480_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000004434 207.0
DTH2_k127_2054480_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000364 187.0
DTH2_k127_2054480_5 binds to the 23S rRNA K02921 - - 0.00000000000000007545 85.0
DTH2_k127_205787_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 403.0
DTH2_k127_205787_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000001623 102.0
DTH2_k127_205787_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.0000000006119 60.0
DTH2_k127_2091856_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 370.0
DTH2_k127_2091856_1 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000004131 212.0
DTH2_k127_2091856_2 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000853 220.0
DTH2_k127_2091856_3 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.000000000000000000000000000000000000000000000000000001417 200.0
DTH2_k127_2091856_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000002245 149.0
DTH2_k127_2091856_5 redox protein regulator of disulfide bond formation - - - 0.0000000000000002821 80.0
DTH2_k127_2091856_6 Thioesterase-like superfamily K07107 - - 0.00000000000005421 77.0
DTH2_k127_2091856_7 Haloacid dehalogenase-like hydrolase K01838 - 5.4.2.6 0.0000000000005343 73.0
DTH2_k127_2091856_8 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000003036 50.0
DTH2_k127_2091856_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0003153 51.0
DTH2_k127_2099432_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 2.758e-198 629.0
DTH2_k127_2099432_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 547.0
DTH2_k127_2099432_10 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 GO:0003674,GO:0003824,GO:0016874,GO:0016879,GO:0016881,GO:0052618 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000005286 203.0
DTH2_k127_2099432_11 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000006578 140.0
DTH2_k127_2099432_12 transmembrane transporter activity K16785,K16786,K16787 - - 0.000000000000000000000000000000000007158 147.0
DTH2_k127_2099432_13 Putative heavy-metal chelation K09138 - - 0.0000000000000000000000000000000007387 140.0
DTH2_k127_2099432_14 CO dehydrogenase/acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.000000000000000000000000000006919 121.0
DTH2_k127_2099432_15 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000002285 102.0
DTH2_k127_2099432_16 Amidohydrolase - - - 0.0000000000000000000003334 105.0
DTH2_k127_2099432_17 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000000000000008435 87.0
DTH2_k127_2099432_19 Acetyltransferase (GNAT) domain - - - 0.000000000000006342 85.0
DTH2_k127_2099432_2 COGs COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase K02031,K02032,K10824,K15587,K16784,K16786,K16787 - 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 469.0
DTH2_k127_2099432_20 COG COG1082 Sugar phosphate isomerases epimerases K10709 - - 0.00000000002823 74.0
DTH2_k127_2099432_21 cellulase activity - - - 0.0000001456 57.0
DTH2_k127_2099432_3 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 452.0
DTH2_k127_2099432_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 444.0
DTH2_k127_2099432_5 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 421.0
DTH2_k127_2099432_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 331.0
DTH2_k127_2099432_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000795 233.0
DTH2_k127_2099432_8 COG3407 Mevalonate pyrophosphate decarboxylase K01597,K17942 - 4.1.1.33,4.1.1.99 0.00000000000000000000000000000000000000000000000000000000001887 218.0
DTH2_k127_2099432_9 c-type cytochrome biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000002811 229.0
DTH2_k127_2126811_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 450.0
DTH2_k127_2126811_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 411.0
DTH2_k127_2126811_10 PFAM bifunctional deaminase-reductase domain protein K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000007001 218.0
DTH2_k127_2126811_11 PFAM NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000001886 191.0
DTH2_k127_2126811_12 response regulator, receiver K07669 - - 0.00000000000000000000000001119 114.0
DTH2_k127_2126811_13 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000004175 116.0
DTH2_k127_2126811_14 Periplasmic binding protein domain K01999 - - 0.00000000000000000000002791 107.0
DTH2_k127_2126811_15 - K00960 - 2.7.7.6 0.0000000000000000003026 87.0
DTH2_k127_2126811_16 GGDEF domain - - - 0.00000000002524 76.0
DTH2_k127_2126811_17 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000003769 57.0
DTH2_k127_2126811_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 370.0
DTH2_k127_2126811_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 364.0
DTH2_k127_2126811_4 Zn-dependent hydrolase, glyoxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 358.0
DTH2_k127_2126811_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 346.0
DTH2_k127_2126811_6 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.0000000000000000000000000000000000000000000000000000000000000000000000001051 258.0
DTH2_k127_2126811_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001003 257.0
DTH2_k127_2126811_8 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001481 247.0
DTH2_k127_2126811_9 Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity K08096 - 3.5.4.29 0.00000000000000000000000000000000000000000000000000000000000000000001756 242.0
DTH2_k127_2140233_0 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000001 202.0
DTH2_k127_2140233_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000003267 178.0
DTH2_k127_2140233_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.00000000000000000000000001001 114.0
DTH2_k127_2140233_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000004866 90.0
DTH2_k127_2140233_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000007992 81.0
DTH2_k127_2140233_5 Belongs to the UPF0218 family K09735 - - 0.0000000000000008453 84.0
DTH2_k127_2140233_6 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000001334 62.0
DTH2_k127_2203071_0 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000654 246.0
DTH2_k127_2203071_1 Conserved hypothetical protein 95 K07579 - - 0.00000000000000000000000000000000000000000002011 169.0
DTH2_k127_2203071_2 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000003209 166.0
DTH2_k127_2203071_3 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.0000000000000000000000000000000000009195 148.0
DTH2_k127_2203071_4 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000001979 99.0
DTH2_k127_2203071_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000749 84.0
DTH2_k127_2294495_0 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 354.0
DTH2_k127_2294495_1 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 301.0
DTH2_k127_2294495_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 290.0
DTH2_k127_2294495_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003849 282.0
DTH2_k127_2294495_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000138 229.0
DTH2_k127_2294495_5 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000131 146.0
DTH2_k127_2294495_6 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000006695 107.0
DTH2_k127_2294495_7 Belongs to the ribosomal protein L31e family K02910 - - 0.00000000000000001013 87.0
DTH2_k127_2294495_8 - K00960 - 2.7.7.6 0.00000000000000004601 81.0
DTH2_k127_2294495_9 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000001013 64.0
DTH2_k127_2340561_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.7e-249 779.0
DTH2_k127_2340561_1 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 349.0
DTH2_k127_2340561_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 308.0
DTH2_k127_2340561_3 PFAM aminotransferase class V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000364 235.0
DTH2_k127_2340561_4 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000001018 205.0
DTH2_k127_2340561_5 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.0000000000000000000000000000000000000000000002295 181.0
DTH2_k127_2340561_6 - - - - 0.00000000000000000000000001546 115.0
DTH2_k127_2340561_7 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000002714 107.0
DTH2_k127_2340561_8 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.0000006433 61.0
DTH2_k127_2340561_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0007856 46.0
DTH2_k127_2358679_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.3e-250 790.0
DTH2_k127_2358679_1 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 559.0
DTH2_k127_2358679_2 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 326.0
DTH2_k127_2358679_3 - - - - 0.000000000000000000000000000000005498 130.0
DTH2_k127_2388025_0 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000002546 231.0
DTH2_k127_2388025_1 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000001834 197.0
DTH2_k127_2388025_2 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000000007163 163.0
DTH2_k127_2388025_3 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000001586 130.0
DTH2_k127_2388025_4 Protein of unknown function (DUF2721) - - - 0.0004832 49.0
DTH2_k127_2407045_0 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000002259 123.0
DTH2_k127_2407045_1 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000008099 109.0
DTH2_k127_2407045_2 Methyltransferase type 11 - - - 0.00000000006736 65.0
DTH2_k127_2407045_3 Maltose acetyltransferase - - - 0.00000006547 64.0
DTH2_k127_2432421_0 PFAM Type II secretion system protein E K07332 - - 0.0000000000000000000000000001298 130.0
DTH2_k127_2432421_1 - - - - 0.00004089 48.0
DTH2_k127_2458023_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 312.0
DTH2_k127_2458023_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000001769 157.0
DTH2_k127_2458023_2 Ser thr protein kinase K07176 - - 0.0000000000000000000000000000000000000004349 158.0
DTH2_k127_2458023_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000006814 85.0
DTH2_k127_2458023_4 Uncharacterised protein family (UPF0175) - - - 0.00009677 52.0
DTH2_k127_2458023_5 nucleic acid-binding protein - - - 0.0001915 51.0
DTH2_k127_2539842_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 1.01e-203 650.0
DTH2_k127_2539842_1 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 473.0
DTH2_k127_2539842_2 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 317.0
DTH2_k127_2539842_3 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000002857 275.0
DTH2_k127_2539842_4 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000009983 206.0
DTH2_k127_2539842_5 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000001721 185.0
DTH2_k127_2539842_6 Prolyl oligopeptidase family - - - 0.0000000000000000000000002603 115.0
DTH2_k127_2539842_7 PFAM ABC transporter related K09695 - - 0.0000002124 53.0
DTH2_k127_2596340_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 533.0
DTH2_k127_2596340_1 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 422.0
DTH2_k127_2596340_11 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.000000000000000000000000000000000001057 151.0
DTH2_k127_2596340_12 NIPSNAP - - - 0.000000000000000000000000000000001195 132.0
DTH2_k127_2596340_13 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000002698 127.0
DTH2_k127_2596340_14 Trm112p-like protein - - - 0.000000000000000000000000006593 111.0
DTH2_k127_2596340_15 Belongs to the SfsA family K01892,K06206 - 6.1.1.21 0.000000000000000000000269 102.0
DTH2_k127_2596340_16 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000003326 99.0
DTH2_k127_2596340_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000009194 83.0
DTH2_k127_2596340_18 Uncharacterised MFS-type transporter YbfB K05548 - - 0.0000000000002448 82.0
DTH2_k127_2596340_19 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000001199 68.0
DTH2_k127_2596340_2 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 355.0
DTH2_k127_2596340_20 - - - - 0.00000000004359 64.0
DTH2_k127_2596340_21 transcriptional - - - 0.0000002213 62.0
DTH2_k127_2596340_22 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000005548 51.0
DTH2_k127_2596340_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 309.0
DTH2_k127_2596340_4 PFAM Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000811 289.0
DTH2_k127_2596340_5 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001989 248.0
DTH2_k127_2596340_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000007892 229.0
DTH2_k127_2596340_7 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000008515 202.0
DTH2_k127_2596340_8 - - - - 0.0000000000000000000000000000000000000000000001515 177.0
DTH2_k127_2596340_9 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000005432 178.0
DTH2_k127_2611993_0 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 431.0
DTH2_k127_2611993_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 304.0
DTH2_k127_2611993_2 Lysine biosynthesis K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 302.0
DTH2_k127_2611993_3 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
DTH2_k127_2657524_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 404.0
DTH2_k127_2657524_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
DTH2_k127_2657524_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000002063 158.0
DTH2_k127_2657524_11 N-terminal domain of galactosyltransferase - - - 0.0000000000000000000000000000000000000005105 162.0
DTH2_k127_2657524_12 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000002744 150.0
DTH2_k127_2657524_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000003097 137.0
DTH2_k127_2657524_14 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001748 129.0
DTH2_k127_2657524_15 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001765 109.0
DTH2_k127_2657524_16 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002981 108.0
DTH2_k127_2657524_17 Binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000006916 108.0
DTH2_k127_2657524_18 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000007098 110.0
DTH2_k127_2657524_19 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000000000001827 99.0
DTH2_k127_2657524_2 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001535 252.0
DTH2_k127_2657524_20 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000002129 90.0
DTH2_k127_2657524_21 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002713 82.0
DTH2_k127_2657524_22 Ribosomal protein S14p/S29e K02980 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000004221 73.0
DTH2_k127_2657524_23 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000006051 59.0
DTH2_k127_2657524_24 membrane - - - 0.00006615 51.0
DTH2_k127_2657524_3 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000003731 241.0
DTH2_k127_2657524_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004414 211.0
DTH2_k127_2657524_5 Binds the lower part of the 30S subunit head K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004087 211.0
DTH2_k127_2657524_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000002553 198.0
DTH2_k127_2657524_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000004804 184.0
DTH2_k127_2657524_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000003268 180.0
DTH2_k127_2657524_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001221 176.0
DTH2_k127_2789371_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 546.0
DTH2_k127_2789371_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 376.0
DTH2_k127_2789371_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 322.0
DTH2_k127_2789371_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000001181 216.0
DTH2_k127_2789371_4 integral membrane protein K00728 - 2.4.1.109 0.000000005649 68.0
DTH2_k127_2789371_5 integral membrane protein - - - 0.00000001359 66.0
DTH2_k127_2789371_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001868 49.0
DTH2_k127_2844387_0 PFAM Amidohydrolase 3 K00200 - 1.2.7.12 3.712e-196 626.0
DTH2_k127_2844387_1 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 467.0
DTH2_k127_2844387_10 Domain of unknown function (DUF296) K06934 - - 0.00000000001174 71.0
DTH2_k127_2844387_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 366.0
DTH2_k127_2844387_3 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 299.0
DTH2_k127_2844387_4 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 300.0
DTH2_k127_2844387_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000007338 270.0
DTH2_k127_2844387_6 PFAM Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003859 258.0
DTH2_k127_2844387_7 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000002464 211.0
DTH2_k127_2844387_8 formylmethanofuran dehydrogenase, subunit C K00202 - 1.2.7.12 0.000000000000000000000000000000000000000001167 166.0
DTH2_k127_2844387_9 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.0000000000000000000000003069 110.0
DTH2_k127_2874883_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 492.0
DTH2_k127_2874883_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002956 290.0
DTH2_k127_2874883_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000003348 177.0
DTH2_k127_2874883_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000001049 175.0
DTH2_k127_2874883_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000008453 168.0
DTH2_k127_2874883_5 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000112 134.0
DTH2_k127_2874883_6 COG1522 Transcriptional regulators - - - 0.00000000001525 69.0
DTH2_k127_2879412_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 604.0
DTH2_k127_2879412_1 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 545.0
DTH2_k127_2879412_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014 - - 0.0000000000000001013 83.0
DTH2_k127_2879412_11 Cyclophilin-like K09143 - - 0.000000000000002719 80.0
DTH2_k127_2879412_12 - K02339 - 2.7.7.7 0.00001787 54.0
DTH2_k127_2879412_13 S25 ribosomal protein K02975 - - 0.00005667 50.0
DTH2_k127_2879412_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 432.0
DTH2_k127_2879412_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 345.0
DTH2_k127_2879412_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 300.0
DTH2_k127_2879412_5 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001007 273.0
DTH2_k127_2879412_6 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000004318 198.0
DTH2_k127_2879412_7 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.00000000000000000000000000000000000000000000000007276 183.0
DTH2_k127_2879412_8 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.00000000000000000000000000000000004891 143.0
DTH2_k127_2879412_9 CBS domain - - - 0.00000000000000000004835 101.0
DTH2_k127_2885330_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000001216 184.0
DTH2_k127_2885330_1 - - - - 0.00000000000005654 76.0
DTH2_k127_2885330_2 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.000000000001295 80.0
DTH2_k127_2949108_0 VIT family - - - 0.000000000000000000000000000000008026 136.0
DTH2_k127_2949108_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000002366 102.0
DTH2_k127_2949108_2 double-strand break repair K09946 - - 0.0000000000001032 72.0
DTH2_k127_2949108_3 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000002021 73.0
DTH2_k127_2951153_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 545.0
DTH2_k127_2951153_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 327.0
DTH2_k127_2951153_10 - - - - 0.00000000006753 74.0
DTH2_k127_2951153_11 Bacterial lipoate protein ligase C-terminus K03800 - 6.3.1.20 0.0000000001278 65.0
DTH2_k127_2951153_12 protein conserved in archaea (DUF2153) - - - 0.000001182 55.0
DTH2_k127_2951153_13 gamma-glutamylcyclotransferase activity - - - 0.0002488 47.0
DTH2_k127_2951153_2 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001758 256.0
DTH2_k127_2951153_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
DTH2_k127_2951153_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000004026 211.0
DTH2_k127_2951153_5 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000006112 207.0
DTH2_k127_2951153_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000008942 181.0
DTH2_k127_2951153_7 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000001168 110.0
DTH2_k127_2951153_8 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000001688 93.0
DTH2_k127_2951153_9 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000008496 88.0
DTH2_k127_2985962_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 312.0
DTH2_k127_2985962_1 Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000008026 199.0
DTH2_k127_2985962_2 PFAM GCN5-related N-acetyltransferase K06718,K22477 - 2.3.1.1,2.3.1.178 0.0000000000000000000000000000000000000000009789 161.0
DTH2_k127_2985962_3 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000002956 149.0
DTH2_k127_2985962_4 pyridoxamine 5'-phosphate - - - 0.000000000000001553 83.0
DTH2_k127_2985962_5 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000001051 60.0
DTH2_k127_2996035_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000001 195.0
DTH2_k127_2996035_1 KaiC - - - 0.0000000000000000000000000000000000002571 151.0
DTH2_k127_2996035_2 Peptidase A24A, prepilin type IV K02278,K07991 - 3.4.23.43,3.4.23.52 0.000111 51.0
DTH2_k127_2997556_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000264 250.0
DTH2_k127_2997556_1 Restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000002509 200.0
DTH2_k127_2997556_2 AsnC family - - - 0.000004217 51.0
DTH2_k127_2997556_3 AsnC family - - - 0.0007807 45.0
DTH2_k127_3138513_0 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006077 261.0
DTH2_k127_3138513_1 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000000000003706 215.0
DTH2_k127_3138513_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000003648 169.0
DTH2_k127_3138513_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000004881 108.0
DTH2_k127_3138513_4 - - - - 0.000000000000002137 81.0
DTH2_k127_3138513_5 RNA-binding protein containing KH domain possibly ribosomal protein K07574 - - 0.00002064 51.0
DTH2_k127_3143412_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.086e-201 641.0
DTH2_k127_3143412_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 574.0
DTH2_k127_3143412_10 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000004554 147.0
DTH2_k127_3143412_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000007378 141.0
DTH2_k127_3143412_12 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000005248 113.0
DTH2_k127_3143412_13 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000006995 109.0
DTH2_k127_3143412_14 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000001908 75.0
DTH2_k127_3143412_15 - - - - 0.00000000000204 76.0
DTH2_k127_3143412_16 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000008774 50.0
DTH2_k127_3143412_17 TM2 domain - - - 0.00001351 55.0
DTH2_k127_3143412_2 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 379.0
DTH2_k127_3143412_3 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 362.0
DTH2_k127_3143412_4 Transporter, major facilitator family protein K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 358.0
DTH2_k127_3143412_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 324.0
DTH2_k127_3143412_6 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003433 283.0
DTH2_k127_3143412_7 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002424 238.0
DTH2_k127_3143412_8 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000001318 161.0
DTH2_k127_3143412_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000008044 154.0
DTH2_k127_3163464_0 peptide catabolic process K13722 - - 3.497e-227 728.0
DTH2_k127_3163464_1 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 330.0
DTH2_k127_3163464_2 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 327.0
DTH2_k127_3163464_3 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 301.0
DTH2_k127_3163464_4 PFAM PAC2 family K06869 - - 0.00000000000000000000000000000000000000000002866 171.0
DTH2_k127_3163464_5 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000008396 152.0
DTH2_k127_3163464_6 Belongs to the peptidase S16 family K06870 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000008157 124.0
DTH2_k127_3163464_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000003525 82.0
DTH2_k127_3163464_8 NADPH-dependent FMN reductase - - - 0.000000000009681 74.0
DTH2_k127_3212164_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 304.0
DTH2_k127_3212164_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 295.0
DTH2_k127_3212164_2 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000005138 231.0
DTH2_k127_3212164_3 Glycosyltransferase 28 domain - - - 0.0000000000000000000000000000000000000000000008839 181.0
DTH2_k127_3212164_4 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000001004 143.0
DTH2_k127_3212164_5 CBS domain - - - 0.0000000000000000000000000000003081 130.0
DTH2_k127_3212164_6 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K01091 - 3.1.3.18 0.00000000005698 71.0
DTH2_k127_3263157_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 332.0
DTH2_k127_3263157_1 cheY-homologous receiver domain - - - 0.000000000000005789 82.0
DTH2_k127_3267827_0 acetyl coenzyme A synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 376.0
DTH2_k127_3267827_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 346.0
DTH2_k127_3267827_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 317.0
DTH2_k127_3267827_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 294.0
DTH2_k127_3267827_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001187 277.0
DTH2_k127_3267827_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000506 124.0
DTH2_k127_3267827_6 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000006624 77.0
DTH2_k127_3471788_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 521.0
DTH2_k127_3471788_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 339.0
DTH2_k127_3471788_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000008822 265.0
DTH2_k127_3471788_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
DTH2_k127_3471788_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000355 215.0
DTH2_k127_3471788_5 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000001595 212.0
DTH2_k127_3471788_6 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000001506 200.0
DTH2_k127_3471788_7 Belongs to the PRA-CH family K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000005098 178.0
DTH2_k127_3471788_8 hydrolase - - - 0.0000000000000000000000003546 119.0
DTH2_k127_3525812_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.443e-197 634.0
DTH2_k127_3525812_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 553.0
DTH2_k127_3525812_2 Phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 304.0
DTH2_k127_3525812_3 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008812 283.0
DTH2_k127_3525812_4 PFAM Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000008286 184.0
DTH2_k127_3525812_5 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000002793 160.0
DTH2_k127_3525812_6 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000102 151.0
DTH2_k127_3525812_7 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000002249 153.0
DTH2_k127_3525812_8 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000000000000000000002073 116.0
DTH2_k127_3585943_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.983e-210 660.0
DTH2_k127_3585943_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001371 275.0
DTH2_k127_3593458_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001794 220.0
DTH2_k127_3593458_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000001122 187.0
DTH2_k127_3593458_2 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000135 185.0
DTH2_k127_3593458_3 COG1100 GTPase SAR1 and related small G K06883 - - 0.000000000000000000000000000000000000000000005792 172.0
DTH2_k127_3593458_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000004986 170.0
DTH2_k127_3593458_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000008456 101.0
DTH2_k127_3593458_6 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000008609 94.0
DTH2_k127_3593458_7 Haloacid dehalogenase-like hydrolase - - - 0.0000000000005019 72.0
DTH2_k127_3593458_8 Transcriptional regulator K07108 - - 0.00000000001468 68.0
DTH2_k127_3611916_0 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000002071 94.0
DTH2_k127_3611916_1 helicase activity K06915 - - 0.0000000001677 74.0
DTH2_k127_3615518_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 9.052e-310 983.0
DTH2_k127_3615518_1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit K07151 GO:0003674,GO:0003824,GO:0004576,GO:0004579,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0031984,GO:0032991,GO:0034645,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043687,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0098796,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000006017 289.0
DTH2_k127_3615518_2 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000001677 187.0
DTH2_k127_3615518_3 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000005219 157.0
DTH2_k127_3615518_4 The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000006116 115.0
DTH2_k127_3615518_5 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000005319 68.0
DTH2_k127_3615518_6 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000004284 65.0
DTH2_k127_3615518_7 - - - - 0.000000007705 61.0
DTH2_k127_361765_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 389.0
DTH2_k127_361765_1 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 387.0
DTH2_k127_361765_10 - - - - 0.000000000000001957 81.0
DTH2_k127_361765_11 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000253 56.0
DTH2_k127_361765_12 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00005441 46.0
DTH2_k127_361765_13 Domain of unknown function (DUF4382) - - - 0.0007529 49.0
DTH2_k127_361765_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 363.0
DTH2_k127_361765_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 356.0
DTH2_k127_361765_4 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 336.0
DTH2_k127_361765_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000006345 206.0
DTH2_k127_361765_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000006092 189.0
DTH2_k127_361765_7 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000001927 148.0
DTH2_k127_361765_8 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000004704 123.0
DTH2_k127_361765_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.000000000000000000000000006264 116.0
DTH2_k127_3632185_0 Heat shock 70 kDa protein K04043 - - 7.362e-197 631.0
DTH2_k127_3632185_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 403.0
DTH2_k127_3632185_10 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000001024 129.0
DTH2_k127_3632185_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000001109 114.0
DTH2_k127_3632185_12 cytochrome c biogenesis protein K06196 - - 0.0000000000000000227 90.0
DTH2_k127_3632185_13 Conserved protein implicated in secretion - - - 0.00006941 51.0
DTH2_k127_3632185_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 391.0
DTH2_k127_3632185_3 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 327.0
DTH2_k127_3632185_4 Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions K03476 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 295.0
DTH2_k127_3632185_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
DTH2_k127_3632185_6 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000006721 218.0
DTH2_k127_3632185_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000001989 211.0
DTH2_k127_3632185_8 protein possibly involved in utilization of glycolate and propanediol - - - 0.00000000000000000000000000000000000000000000008154 172.0
DTH2_k127_3632185_9 - - - - 0.000000000000000000000000000000001859 142.0
DTH2_k127_3684964_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000009161 199.0
DTH2_k127_3684964_1 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.000000000000000000000000000000000000000000000004475 183.0
DTH2_k127_3684964_2 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000003707 156.0
DTH2_k127_3684964_3 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000004188 89.0
DTH2_k127_3684964_4 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.00000000000000002218 85.0
DTH2_k127_3684964_5 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.00000000000001725 77.0
DTH2_k127_371474_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 316.0
DTH2_k127_371474_1 - - - - 0.00000000000000000000000000000000000000000000000000000008649 205.0
DTH2_k127_371474_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000000000000000000002532 189.0
DTH2_k127_371474_3 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000000000000000000000004276 137.0
DTH2_k127_371474_4 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.000000000000003364 81.0
DTH2_k127_371474_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000000006032 80.0
DTH2_k127_371474_6 Protein of unknown function (DUF447) K09154 - - 0.00000001057 64.0
DTH2_k127_371474_7 rRNA binding K02944 - - 0.00000005186 58.0
DTH2_k127_3729580_0 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 542.0
DTH2_k127_3729580_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 411.0
DTH2_k127_3729580_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003332 280.0
DTH2_k127_3729580_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000001302 275.0
DTH2_k127_3729580_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000002395 210.0
DTH2_k127_3729580_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000001 195.0
DTH2_k127_3729580_6 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000003452 160.0
DTH2_k127_3729580_7 COG1522 Transcriptional regulators K03718 - - 0.000000000000000000000000000231 122.0
DTH2_k127_3729580_8 synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000001176 120.0
DTH2_k127_3729580_9 - - - - 0.0001596 53.0
DTH2_k127_375789_0 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000003492 218.0
DTH2_k127_375789_1 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000003503 184.0
DTH2_k127_375789_2 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000000000569 121.0
DTH2_k127_3789005_0 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000002418 122.0
DTH2_k127_3789005_1 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000418 115.0
DTH2_k127_3789005_2 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 0.00000000000000000003323 93.0
DTH2_k127_3789005_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000002225 74.0
DTH2_k127_3789005_4 Segregation and condensation protein ScpA K05896 - - 0.0000000000005896 77.0
DTH2_k127_3790801_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 374.0
DTH2_k127_3790801_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000005244 236.0
DTH2_k127_3790801_2 short-chain K00034,K00038,K00046 - 1.1.1.47,1.1.1.53,1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000009276 221.0
DTH2_k127_3790801_3 Domain of unknown function (DUF2088) - - - 0.000000002709 63.0
DTH2_k127_3804779_0 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 490.0
DTH2_k127_3804779_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 368.0
DTH2_k127_3804779_2 Protein of unknown function (DUF1512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 312.0
DTH2_k127_3804779_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001348 263.0
DTH2_k127_3804779_4 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000003839 218.0
DTH2_k127_3804779_5 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000008448 160.0
DTH2_k127_3804779_6 Helix-turn-helix domain - - - 0.000000000000000000000000000000000005278 143.0
DTH2_k127_3804779_7 Putative cyclase - - - 0.0000000000000000000000000009918 123.0
DTH2_k127_3804779_8 Domain of unknown function (DUF4405) - - - 0.000000002387 62.0
DTH2_k127_3804779_9 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000002536 60.0
DTH2_k127_3808290_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001518 275.0
DTH2_k127_3808290_1 Belongs to the UPF0200 family - - - 0.0000000000000000000000003417 107.0
DTH2_k127_3808290_2 Belongs to the UPF0201 family K09736 - - 0.000000000003289 72.0
DTH2_k127_3868386_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 608.0
DTH2_k127_3868386_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 500.0
DTH2_k127_3868386_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000009803 235.0
DTH2_k127_3868386_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000002664 124.0
DTH2_k127_3868386_4 ThiS family K03636 - - 0.00000004586 59.0
DTH2_k127_3883_0 Luciferase-like monooxygenase K14728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 342.0
DTH2_k127_3883_1 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 323.0
DTH2_k127_3883_2 acetyltransferase K06323 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000001351 180.0
DTH2_k127_3883_3 Sugar (and other) transporter - - - 0.00000000000000000000000000002515 131.0
DTH2_k127_3883_4 Phosphoserine phosphatase K01079,K05967,K07025 - 3.1.3.3 0.00000000000000005517 88.0
DTH2_k127_3946888_0 AAA-like domain - - - 1.483e-268 851.0
DTH2_k127_3946888_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 456.0
DTH2_k127_3946888_10 transcriptional regulator, AsnC family - - - 0.000000000000000000000000000000001088 135.0
DTH2_k127_3946888_11 synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000035 144.0
DTH2_k127_3946888_12 SMART Transcription regulator, AsnC-type - - - 0.00000000000000000000000005979 122.0
DTH2_k127_3946888_2 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 428.0
DTH2_k127_3946888_3 SMART Elongator protein 3 MiaB NifB K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 426.0
DTH2_k127_3946888_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 322.0
DTH2_k127_3946888_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001283 286.0
DTH2_k127_3946888_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004445 283.0
DTH2_k127_3946888_7 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004644 274.0
DTH2_k127_3946888_8 Protein of unknown function (DUF402) K07586,K09145 - - 0.000000000000000000000000000000000000000000000001415 186.0
DTH2_k127_3946888_9 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000002984 173.0
DTH2_k127_4063587_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 340.0
DTH2_k127_4063587_1 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 310.0
DTH2_k127_4063587_10 - - - - 0.0000000000000000000000000000000000001483 148.0
DTH2_k127_4063587_11 PFAM Dimethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000028 140.0
DTH2_k127_4063587_12 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000002035 125.0
DTH2_k127_4063587_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000005602 121.0
DTH2_k127_4063587_14 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000001416 111.0
DTH2_k127_4063587_15 Peptidase C13 family - - - 0.0000000000002204 83.0
DTH2_k127_4063587_16 von Willebrand factor (vWF) type A domain - - - 0.0000000000006808 81.0
DTH2_k127_4063587_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000004276 71.0
DTH2_k127_4063587_18 Transporter - - - 0.00000001339 65.0
DTH2_k127_4063587_19 PFAM protein phosphatase 2C K01090 - 3.1.3.16 0.00001147 49.0
DTH2_k127_4063587_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 300.0
DTH2_k127_4063587_20 - - - - 0.00004083 55.0
DTH2_k127_4063587_3 Spore germination protein K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007669 274.0
DTH2_k127_4063587_4 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004613 247.0
DTH2_k127_4063587_5 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001593 233.0
DTH2_k127_4063587_6 COG1199 Rad3-related DNA helicases - - - 0.00000000000000000000000000000000000000000000000000000000001926 227.0
DTH2_k127_4063587_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K19647 - 1.1.1.291,1.1.1.31 0.0000000000000000000000000000000000000000000000000000000008797 212.0
DTH2_k127_4063587_8 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000007115 166.0
DTH2_k127_4063587_9 Protein of unknown function DUF134 - - - 0.0000000000000000000000000000000000000001629 154.0
DTH2_k127_4086716_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000003078 164.0
DTH2_k127_4086716_1 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000001327 153.0
DTH2_k127_4225536_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000007543 176.0
DTH2_k127_4225536_1 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000458 157.0
DTH2_k127_4225536_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000002931 119.0
DTH2_k127_4225536_3 PIN domain of ribonuclease K07060 GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904 - 0.00000000000000007055 88.0
DTH2_k127_4229366_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003979 282.0
DTH2_k127_4229366_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002226 267.0
DTH2_k127_4249510_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 8.575e-205 649.0
DTH2_k127_4249510_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 573.0
DTH2_k127_4249510_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 427.0
DTH2_k127_4249510_3 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 426.0
DTH2_k127_4249510_4 ATP-NAD kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 418.0
DTH2_k127_4249510_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 347.0
DTH2_k127_4249510_6 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000002768 142.0
DTH2_k127_4270583_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000001465 247.0
DTH2_k127_4270583_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000001706 196.0
DTH2_k127_4270583_3 metallopeptidase activity - - - 0.0006452 48.0
DTH2_k127_4288665_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006042 278.0
DTH2_k127_4288665_1 PhoU domain K02039 - - 0.000000000000000000000000000000000000000006418 162.0
DTH2_k127_4288665_2 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000009574 147.0
DTH2_k127_4288665_3 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000008566 81.0
DTH2_k127_4288665_4 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000001023 79.0
DTH2_k127_4297720_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 397.0
DTH2_k127_4297720_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000001262 134.0
DTH2_k127_4346911_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 4.646e-222 697.0
DTH2_k127_4346911_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000007274 254.0
DTH2_k127_4346911_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000005344 133.0
DTH2_k127_4346911_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000001017 121.0
DTH2_k127_4346911_4 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000001682 74.0
DTH2_k127_4346911_5 - - - - 0.00001479 50.0
DTH2_k127_4373157_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 523.0
DTH2_k127_4373157_1 Psort location Cytoplasmic, score K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 400.0
DTH2_k127_4373157_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000002214 247.0
DTH2_k127_4373157_3 PFAM ABC transporter related K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000002264 224.0
DTH2_k127_4373157_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000001869 169.0
DTH2_k127_4373157_5 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000001035 128.0
DTH2_k127_4373157_6 ABC-type multidrug transport system, permease component K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000002264 94.0
DTH2_k127_4373157_7 PFAM SNARE associated Golgi protein - - - 0.0000000000000004219 87.0
DTH2_k127_4373157_8 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.00000000002971 75.0
DTH2_k127_4403377_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 417.0
DTH2_k127_4543532_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 363.0
DTH2_k127_4543532_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 344.0
DTH2_k127_4543532_10 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000003 133.0
DTH2_k127_4543532_11 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000005231 78.0
DTH2_k127_4543532_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
DTH2_k127_4543532_3 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000003927 245.0
DTH2_k127_4543532_4 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001596 237.0
DTH2_k127_4543532_5 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000002984 191.0
DTH2_k127_4543532_6 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000002433 179.0
DTH2_k127_4543532_7 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000004026 178.0
DTH2_k127_4543532_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000851 158.0
DTH2_k127_4543532_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000001009 166.0
DTH2_k127_4559161_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.691e-219 691.0
DTH2_k127_4587602_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 594.0
DTH2_k127_4587602_1 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000291 260.0
DTH2_k127_4587602_2 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000004582 162.0
DTH2_k127_4587602_3 Oxidoreductase family, C-terminal alpha/beta domain K18855 - 1.1.1.374 0.00000000000000000000000000001374 128.0
DTH2_k127_4587602_4 PFAM ABC transporter related K01995 - - 0.00000000000000000000000007033 109.0
DTH2_k127_4587602_5 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000004296 83.0
DTH2_k127_4587602_6 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.000000000000002582 82.0
DTH2_k127_4588423_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 497.0
DTH2_k127_4588423_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007668 230.0
DTH2_k127_4643387_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000001231 157.0
DTH2_k127_4676041_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.418e-194 619.0
DTH2_k127_4676041_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 405.0
DTH2_k127_4676041_10 snRNP Sm proteins K04796 - - 0.0000000000002435 72.0
DTH2_k127_4676041_2 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000003016 245.0
DTH2_k127_4676041_3 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.00000000000000000000000000000000000000000000000000005182 196.0
DTH2_k127_4676041_4 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000000000007279 134.0
DTH2_k127_4676041_5 serine-type endopeptidase activity K00505,K01342,K02035 - 1.14.18.1,3.4.21.62 0.000000000000000000000000000009154 138.0
DTH2_k127_4676041_7 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000000000000000000084 97.0
DTH2_k127_4676041_8 PFAM ParB domain protein nuclease - - - 0.00000000000000008 89.0
DTH2_k127_4676041_9 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000006415 79.0
DTH2_k127_4689228_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 579.0
DTH2_k127_4689228_1 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 317.0
DTH2_k127_4689228_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000707 244.0
DTH2_k127_4689228_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000004356 64.0
DTH2_k127_4689228_4 Branched-chain amino acid transport K01995,K01996 - - 0.000000001509 59.0
DTH2_k127_4724373_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1651.0
DTH2_k127_4724373_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.987e-303 953.0
DTH2_k127_4724373_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00004708 53.0
DTH2_k127_4724373_11 RHS Repeat - - - 0.0001115 53.0
DTH2_k127_4724373_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 4.26e-225 719.0
DTH2_k127_4724373_3 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 510.0
DTH2_k127_4724373_4 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 374.0
DTH2_k127_4724373_5 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
DTH2_k127_4724373_6 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000008721 195.0
DTH2_k127_4724373_7 Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000001254 203.0
DTH2_k127_4724373_8 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000001783 151.0
DTH2_k127_4724373_9 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000003445 96.0
DTH2_k127_4754046_0 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000002677 190.0
DTH2_k127_4754046_1 PFAM Glycosyl transferase, group 1 K00754 - - 0.00000000000000000000000003847 122.0
DTH2_k127_4754046_2 PFAM Glycosyl transferase family 2 - - - 0.0005679 45.0
DTH2_k127_4755141_0 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 306.0
DTH2_k127_4755141_1 HMGL-like K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000005254 255.0
DTH2_k127_4755141_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000189 231.0
DTH2_k127_4755141_3 methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000001797 190.0
DTH2_k127_4755141_4 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000001376 143.0
DTH2_k127_4755141_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000001488 87.0
DTH2_k127_4755141_6 RDD family - - - 0.000000000000003857 81.0
DTH2_k127_4764236_0 Radical SAM K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000001935 241.0
DTH2_k127_4764236_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000008472 114.0
DTH2_k127_4764236_2 Methyltransferase FkbM domain - - - 0.000004012 53.0
DTH2_k127_483652_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 440.0
DTH2_k127_483652_1 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 409.0
DTH2_k127_483652_10 Hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000000000000001383 121.0
DTH2_k127_483652_11 phosphatidylinositol metabolic process - - - 0.000000000000000000000000005969 124.0
DTH2_k127_483652_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14091 - - 0.0000000000000000002349 91.0
DTH2_k127_483652_13 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.0000000000000000004295 93.0
DTH2_k127_483652_14 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000007521 79.0
DTH2_k127_483652_15 Belongs to the UPF0273 family - - - 0.0000000007166 72.0
DTH2_k127_483652_17 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.0000007046 63.0
DTH2_k127_483652_18 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000003812 51.0
DTH2_k127_483652_19 Nucleotidyltransferase domain K07076 - - 0.000007896 51.0
DTH2_k127_483652_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 343.0
DTH2_k127_483652_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
DTH2_k127_483652_4 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 317.0
DTH2_k127_483652_5 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002581 267.0
DTH2_k127_483652_6 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003984 252.0
DTH2_k127_483652_7 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.0000000000000000000000000000000000000000000000000000000271 201.0
DTH2_k127_483652_8 Belongs to the UPF0273 family - - - 0.000000000000000000000000000000000001347 147.0
DTH2_k127_483652_9 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.000000000000000000000000000000009822 135.0
DTH2_k127_4893887_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002147 274.0
DTH2_k127_4893887_1 Protein of unknown function (DUF521) K09123 - - 0.0000000000000004805 82.0
DTH2_k127_4899443_0 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000002259 197.0
DTH2_k127_4899443_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000003955 197.0
DTH2_k127_4899443_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000006482 150.0
DTH2_k127_4935747_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000254 144.0
DTH2_k127_4935747_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000003281 76.0
DTH2_k127_4935747_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000002468 82.0
DTH2_k127_4935747_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000008573 77.0
DTH2_k127_4935747_4 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000004012 53.0
DTH2_k127_4935747_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000004316 58.0
DTH2_k127_4939281_0 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 306.0
DTH2_k127_4939281_1 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000003585 276.0
DTH2_k127_4939281_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000004725 228.0
DTH2_k127_4939281_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000001918 162.0
DTH2_k127_4939281_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000009803 136.0
DTH2_k127_4939281_5 PFAM Phosphatidylglycerophosphatase A - - - 0.000000000000000000000000000006924 132.0
DTH2_k127_4939281_6 Cytidylyltransferase K19712 - 2.7.7.62 0.000000000000000000000000001299 117.0
DTH2_k127_4939281_7 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000131 95.0
DTH2_k127_5060027_0 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000001824 197.0
DTH2_k127_5060027_1 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000003655 113.0
DTH2_k127_5060027_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0001086 45.0
DTH2_k127_5108978_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 444.0
DTH2_k127_5108978_1 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 395.0
DTH2_k127_5108978_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001672 91.0
DTH2_k127_5108978_11 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000008223 66.0
DTH2_k127_5108978_12 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000001807 55.0
DTH2_k127_5108978_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000001032 53.0
DTH2_k127_5108978_14 acid phosphatase activity - - - 0.0002965 53.0
DTH2_k127_5108978_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 391.0
DTH2_k127_5108978_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 306.0
DTH2_k127_5108978_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000006238 220.0
DTH2_k127_5108978_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000005622 202.0
DTH2_k127_5108978_6 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005183 199.0
DTH2_k127_5108978_7 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000003259 185.0
DTH2_k127_5108978_8 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000008768 142.0
DTH2_k127_5108978_9 Transcription elongation factor - - - 0.00000000000000000000001356 106.0
DTH2_k127_5164438_0 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 306.0
DTH2_k127_5164438_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000008217 177.0
DTH2_k127_5195306_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 1.458e-211 672.0
DTH2_k127_5195306_1 metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain K07041 - - 2.564e-210 671.0
DTH2_k127_5195306_10 snRNP Sm proteins K04796 - - 0.00000000000000000000001626 101.0
DTH2_k127_5195306_11 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001396 98.0
DTH2_k127_5195306_12 Parallel beta-helix repeats - - - 0.000000001633 70.0
DTH2_k127_5195306_13 - - - - 0.0000004862 60.0
DTH2_k127_5195306_2 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 1.543e-203 647.0
DTH2_k127_5195306_3 PFAM dihydropteroate synthase, DHPS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 314.0
DTH2_k127_5195306_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000001774 216.0
DTH2_k127_5195306_5 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000009825 215.0
DTH2_k127_5195306_6 ERCC4 domain K10896 - - 0.000000000000000000000000000000000000000000008236 177.0
DTH2_k127_5195306_7 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000003346 166.0
DTH2_k127_5195306_8 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000002383 133.0
DTH2_k127_5195306_9 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000004235 108.0
DTH2_k127_5341276_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 7.865e-201 642.0
DTH2_k127_5341276_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 396.0
DTH2_k127_5341276_10 ATP synthase (E/31 kDa) subunit K02150 GO:0000221,GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015988,GO:0015991,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016471,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019725,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0031090,GO:0031224,GO:0032991,GO:0033176,GO:0033178,GO:0033180,GO:0034220,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045851,GO:0046961,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0090662,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098796,GO:0098805,GO:0098852,GO:0099131,GO:0099132,GO:1902600 - 0.00004589 53.0
DTH2_k127_5341276_11 H subunit K02107 - - 0.0001686 48.0
DTH2_k127_5341276_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 293.0
DTH2_k127_5341276_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000001115 191.0
DTH2_k127_5341276_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000006661 139.0
DTH2_k127_5341276_5 anthranilate phosphoribosyltransferase activity K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000001455 94.0
DTH2_k127_5341276_6 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000008024 80.0
DTH2_k127_5341276_7 - - - - 0.0000000002284 66.0
DTH2_k127_5341276_9 Universal stress protein K06149 - - 0.0000007867 57.0
DTH2_k127_5423620_0 THUMP domain K06963 - - 0.000000000000000000000000000000008835 133.0
DTH2_k127_5423620_1 molybdopterin binding domain - - - 0.000000000000000000000000000008991 129.0
DTH2_k127_5423620_2 HAD-hyrolase-like K07025,K08723 - 3.1.3.5 0.00000000000000001131 92.0
DTH2_k127_5423620_3 protein conserved in archaea - - - 0.000000005123 65.0
DTH2_k127_5423620_4 Kinase binding protein CGI-121 K09119 - - 0.000000006053 64.0
DTH2_k127_5435358_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 479.0
DTH2_k127_5435358_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 425.0
DTH2_k127_5435358_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 296.0
DTH2_k127_5435358_3 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000003259 183.0
DTH2_k127_5435358_4 Ribosome biogenesis protein, C-terminal K09140 - - 0.0000000000000000000000000000000002119 138.0
DTH2_k127_5435358_5 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000002319 113.0
DTH2_k127_5435358_6 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.00000000000000002297 83.0
DTH2_k127_5435358_7 PAC2 family K07159 - - 0.00000000096 67.0
DTH2_k127_5435358_8 Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP K11176 - 3.5.4.10 0.000000005659 65.0
DTH2_k127_5435358_9 Transcriptional regulator, TrmB - - - 0.000005069 52.0
DTH2_k127_5471910_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000002196 187.0
DTH2_k127_5471910_1 Peptidyl-tRNA hydrolase PTH2 K04794,K18177 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0010941,GO:0010942,GO:0016787,GO:0016788,GO:0019222,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0052689,GO:0060255,GO:0060548,GO:0065007,GO:0140098,GO:0140101,GO:2000209,GO:2000210,GO:2000811 3.1.1.29 0.0000000000000000000000000000002577 126.0
DTH2_k127_5471910_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000006758 93.0
DTH2_k127_5471910_3 exosome subunit K07581 - - 0.00000000000000007971 87.0
DTH2_k127_5471910_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000001641 79.0
DTH2_k127_5471910_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000000002276 76.0
DTH2_k127_5471910_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00004291 52.0
DTH2_k127_5493939_0 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.0000000000000000008934 97.0
DTH2_k127_5493939_1 methionine synthase - - - 0.000000000008715 74.0
DTH2_k127_5537172_0 COGs COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase K00020,K00042,K19647 - 1.1.1.291,1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000008671 244.0
DTH2_k127_5537172_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000004676 228.0
DTH2_k127_5537172_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000004237 154.0
DTH2_k127_5537172_3 Nucleotidyltransferase domain K07076 - - 0.00000000000000000000000000000000000004263 159.0
DTH2_k127_5537172_4 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000001438 144.0
DTH2_k127_5537172_5 - - - - 0.0000003906 55.0
DTH2_k127_5544399_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1091.0
DTH2_k127_5544399_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 8.357e-297 947.0
DTH2_k127_5544399_10 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001538 204.0
DTH2_k127_5544399_11 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000004669 152.0
DTH2_k127_5544399_12 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000001122 147.0
DTH2_k127_5544399_13 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000002201 124.0
DTH2_k127_5544399_14 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000003564 119.0
DTH2_k127_5544399_15 Universal stress protein - - - 0.00000000000000000000000001371 114.0
DTH2_k127_5544399_16 YbaK prolyl-tRNA synthetase associated K03976 - - 0.000000000000000000001975 100.0
DTH2_k127_5544399_17 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000008517 95.0
DTH2_k127_5544399_18 pfam cbs - - - 0.000000000000008844 79.0
DTH2_k127_5544399_19 PFAM Rhomboid family protein - - - 0.0000000000001412 79.0
DTH2_k127_5544399_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 449.0
DTH2_k127_5544399_20 - - - - 0.0000000000001598 76.0
DTH2_k127_5544399_21 Transcription elongation factor Elf1 like - - - 0.000000000573 63.0
DTH2_k127_5544399_22 Sec61beta family - - - 0.0000003972 54.0
DTH2_k127_5544399_23 regulatory protein, arsR - - - 0.000611 46.0
DTH2_k127_5544399_24 - - - - 0.0006493 51.0
DTH2_k127_5544399_3 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 445.0
DTH2_k127_5544399_4 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 394.0
DTH2_k127_5544399_5 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 347.0
DTH2_k127_5544399_6 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 341.0
DTH2_k127_5544399_7 Beta-lactamase superfamily domain K03476 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 291.0
DTH2_k127_5544399_8 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000001552 237.0
DTH2_k127_5544399_9 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000006666 204.0
DTH2_k127_5583396_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 519.0
DTH2_k127_5583396_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 434.0
DTH2_k127_5583396_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002088 70.0
DTH2_k127_5583396_11 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00002579 57.0
DTH2_k127_5583396_2 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 424.0
DTH2_k127_5583396_3 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00018 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26,1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 381.0
DTH2_k127_5583396_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
DTH2_k127_5583396_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001148 229.0
DTH2_k127_5583396_6 - - - - 0.0000000000000000000000000000000000000000000000000000004497 199.0
DTH2_k127_5583396_7 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000005623 192.0
DTH2_k127_5583396_8 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000000000000000009599 164.0
DTH2_k127_5583396_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000008819 133.0
DTH2_k127_5605791_0 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 407.0
DTH2_k127_5605791_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 304.0
DTH2_k127_5605791_2 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000004692 220.0
DTH2_k127_5605791_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.0000000000000000000000000000000000000000000001753 171.0
DTH2_k127_5605791_4 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000006561 117.0
DTH2_k127_5605791_5 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K00123,K00390,K00441,K03388,K14121,K22174 - 1.1.98.4,1.12.98.1,1.17.1.9,1.8.4.10,1.8.4.8,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000007885 113.0
DTH2_k127_5606909_0 DNA polymerase K02319 - 2.7.7.7 4.744e-243 777.0
DTH2_k127_5606909_1 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000007235 249.0
DTH2_k127_5628788_0 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 304.0
DTH2_k127_5628788_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000007445 269.0
DTH2_k127_5628788_2 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000004483 191.0
DTH2_k127_5628788_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000007937 197.0
DTH2_k127_5628788_4 Amidohydrolase family - - - 0.0000000000000000007363 98.0
DTH2_k127_5635515_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000004119 235.0
DTH2_k127_5635515_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000000000000000000000000000000000000001292 207.0
DTH2_k127_5635515_10 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000006365 74.0
DTH2_k127_5635515_11 ACT domain - - - 0.0000001297 59.0
DTH2_k127_5635515_2 Belongs to the V-ATPase 116 kDa subunit family K02123 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000004444 216.0
DTH2_k127_5635515_3 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000001427 181.0
DTH2_k127_5635515_4 Rieske 2Fe-2S - - - 0.000000000000000000000000000000142 127.0
DTH2_k127_5635515_5 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.00000000000000000000000000001553 134.0
DTH2_k127_5635515_6 Glutaredoxin - - - 0.000000000000000000000000002319 113.0
DTH2_k127_5635515_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000003761 99.0
DTH2_k127_5635515_8 Archaeal vacuolar-type H -ATPase subunit C K02119 - - 0.00000000000000000006382 102.0
DTH2_k127_5635515_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000001588 81.0
DTH2_k127_5730888_0 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000001085 135.0
DTH2_k127_5730888_1 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000000143 120.0
DTH2_k127_5730888_2 Glutaredoxin - - - 0.0000000000000000000000000003239 115.0
DTH2_k127_5730888_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000001423 78.0
DTH2_k127_5733087_0 COG0433 Predicted ATPase K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 391.0
DTH2_k127_5733087_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 248.0
DTH2_k127_5733087_2 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000006855 236.0
DTH2_k127_5733087_3 PFAM NurA domain - - - 0.000000000000000001449 98.0
DTH2_k127_5733087_4 Ribosomal protein S30 K02983 - - 0.0000000007156 62.0
DTH2_k127_5772036_0 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003061 282.0
DTH2_k127_5772036_1 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002174 263.0
DTH2_k127_5772036_2 Glutathione peroxidase K02199 - - 0.000000000000000002481 93.0
DTH2_k127_5819725_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 368.0
DTH2_k127_5819725_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001991 263.0
DTH2_k127_5819725_2 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000001109 240.0
DTH2_k127_5819725_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000003425 153.0
DTH2_k127_5819725_4 WD40-like Beta Propeller Repeat - - - 0.000000000000001469 88.0
DTH2_k127_5869068_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 384.0
DTH2_k127_5869068_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 364.0
DTH2_k127_5869068_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 356.0
DTH2_k127_5869068_3 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 321.0
DTH2_k127_5869068_4 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000001262 257.0
DTH2_k127_5869068_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000004257 191.0
DTH2_k127_5869068_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000005516 171.0
DTH2_k127_5869068_7 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000009158 156.0
DTH2_k127_5972691_0 AIR synthase related protein, C-terminal domain K01952 - 6.3.5.3 2.04e-210 677.0
DTH2_k127_5972691_1 DEAD DEAH box helicase domain protein K03724 - - 1.529e-203 665.0
DTH2_k127_5972691_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000004157 225.0
DTH2_k127_5972691_11 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000002183 192.0
DTH2_k127_5972691_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000001518 172.0
DTH2_k127_5972691_13 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.000000000000000000000000000000000000000001848 179.0
DTH2_k127_5972691_14 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000000000000000001629 136.0
DTH2_k127_5972691_15 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000142 144.0
DTH2_k127_5972691_16 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.00000000000000000000000000006888 117.0
DTH2_k127_5972691_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000009377 89.0
DTH2_k127_5972691_18 GCN5-related N-acetyl-transferase - - - 0.0000000007311 63.0
DTH2_k127_5972691_19 - - - - 0.00000004086 60.0
DTH2_k127_5972691_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 3.467e-203 662.0
DTH2_k127_5972691_20 - - - - 0.0000003469 58.0
DTH2_k127_5972691_21 molybdopterin-guanine dinucleotide biosynthesis protein K03635,K03753 - 2.8.1.12 0.0002209 47.0
DTH2_k127_5972691_3 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 579.0
DTH2_k127_5972691_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 434.0
DTH2_k127_5972691_5 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 398.0
DTH2_k127_5972691_6 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 348.0
DTH2_k127_5972691_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 322.0
DTH2_k127_5972691_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 313.0
DTH2_k127_5972691_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005366 269.0
DTH2_k127_6034550_0 PFAM UDP-glucuronosyl UDP-glucosyltransferase - - - 0.00000000000000000000000000000009386 139.0
DTH2_k127_6034550_1 Nitroreductase family - - - 0.0000000000001634 80.0
DTH2_k127_6034550_2 Protein of unknown function (DUF3795) - - - 0.00001401 47.0
DTH2_k127_6061459_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 5.071e-200 641.0
DTH2_k127_6061459_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 511.0
DTH2_k127_6061459_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 437.0
DTH2_k127_6061459_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 426.0
DTH2_k127_6061459_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 389.0
DTH2_k127_6061459_5 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002237 282.0
DTH2_k127_6061459_6 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004339 276.0
DTH2_k127_6061459_7 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000001304 141.0
DTH2_k127_6061459_8 chorismate mutase K14187 - 1.3.1.12,5.4.99.5 0.0000000000000000000000000008103 124.0
DTH2_k127_6061459_9 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000162 59.0
DTH2_k127_6088031_0 Dodecin K09165 - - 0.00000000000000000003129 92.0
DTH2_k127_6088031_1 - - - - 0.0000000000004818 70.0
DTH2_k127_6171528_0 Uncharacterised protein family (UPF0182) K09118 - - 5.763e-266 848.0
DTH2_k127_6171528_1 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001053 272.0
DTH2_k127_6171528_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000003239 111.0
DTH2_k127_6171528_11 metal-dependent protease of the PAD1 JAB1 superfamily K20110 - 3.4.19.15 0.0000000000000006785 83.0
DTH2_k127_6171528_12 - - - - 0.00000000003957 69.0
DTH2_k127_6171528_13 COG0517 FOG CBS domain - - - 0.000000008761 67.0
DTH2_k127_6171528_2 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
DTH2_k127_6171528_3 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004032 251.0
DTH2_k127_6171528_4 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000001439 242.0
DTH2_k127_6171528_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000001091 215.0
DTH2_k127_6171528_6 Amino acid kinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000001527 215.0
DTH2_k127_6171528_7 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000001442 158.0
DTH2_k127_6171528_8 Winged helix-turn-helix - - - 0.0000000000000000000000000000000001085 135.0
DTH2_k127_6171528_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000007588 131.0
DTH2_k127_6172963_0 PFAM ABC transporter related K03529,K06166,K16786,K16787 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000002613 227.0
DTH2_k127_6172963_1 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000001998 171.0
DTH2_k127_6184736_0 Membrane dipeptidase (Peptidase family M19) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 368.0
DTH2_k127_6184736_1 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 368.0
DTH2_k127_6184736_2 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001768 291.0
DTH2_k127_6184736_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007612 280.0
DTH2_k127_6184736_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000889 180.0
DTH2_k127_6184736_5 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000003764 127.0
DTH2_k127_6184736_6 B12 binding domain - - - 0.0000000846 56.0
DTH2_k127_6219633_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000001037 246.0
DTH2_k127_6277741_0 GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 390.0
DTH2_k127_6277741_1 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000005385 166.0
DTH2_k127_6277741_2 cellulose binding - - - 0.0000000000000000002326 102.0
DTH2_k127_6277741_3 Putative zinc- or iron-chelating domain K06940 - - 0.000000000628 66.0
DTH2_k127_6277741_4 - - - - 0.000001183 53.0
DTH2_k127_6277741_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00004313 48.0
DTH2_k127_6282984_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.112e-213 678.0
DTH2_k127_6282984_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.985e-201 644.0
DTH2_k127_6282984_10 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000003276 204.0
DTH2_k127_6282984_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000006819 176.0
DTH2_k127_6282984_12 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000000000000006265 157.0
DTH2_k127_6282984_13 KaiC - - - 0.000000000000000000000000000000000000001797 157.0
DTH2_k127_6282984_14 hydrolase activity - - - 0.000000000000000000000000000000000001613 145.0
DTH2_k127_6282984_15 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000004012 125.0
DTH2_k127_6282984_16 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000273 114.0
DTH2_k127_6282984_17 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000001256 96.0
DTH2_k127_6282984_18 transcriptional regulator PadR family - - - 0.0000000000001056 76.0
DTH2_k127_6282984_19 - - - - 0.000000000165 74.0
DTH2_k127_6282984_2 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 475.0
DTH2_k127_6282984_20 Signal peptidase K13280 GO:0003674,GO:0003824,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 3.4.21.89 0.00000006491 61.0
DTH2_k127_6282984_3 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 389.0
DTH2_k127_6282984_4 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 386.0
DTH2_k127_6282984_5 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 316.0
DTH2_k127_6282984_6 Type III effector Hrp-dependent K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 302.0
DTH2_k127_6282984_7 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002243 279.0
DTH2_k127_6282984_8 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001852 243.0
DTH2_k127_6282984_9 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000006989 211.0
DTH2_k127_6289759_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 482.0
DTH2_k127_6289759_1 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000000000000000000000001367 218.0
DTH2_k127_6289759_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000001014 177.0
DTH2_k127_6289759_3 TIGRFAM thiW protein - - - 0.000000000000000000000000000000000001261 144.0
DTH2_k127_6289759_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001655 108.0
DTH2_k127_6289759_5 polynucleotide 5'-hydroxyl-kinase activity K06947 - - 0.0002412 49.0
DTH2_k127_6289759_6 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0004734 47.0
DTH2_k127_6289759_7 Cytochrome D1 heme domain - - - 0.0006157 48.0
DTH2_k127_6378867_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 541.0
DTH2_k127_6378867_1 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000002292 269.0
DTH2_k127_6430657_0 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000009551 205.0
DTH2_k127_6430657_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000007972 143.0
DTH2_k127_6430657_2 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000158 143.0
DTH2_k127_6431813_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 317.0
DTH2_k127_6431813_1 Protein of unknown function (DUF998) - - - 0.0000000000000002534 87.0
DTH2_k127_6431813_2 DsrE/DsrF-like family - - - 0.00000000001938 64.0
DTH2_k127_6542389_0 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 510.0
DTH2_k127_6542389_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 368.0
DTH2_k127_6542389_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 367.0
DTH2_k127_6542389_3 H ACA RNA-protein complex K07569 - - 0.0000000000001692 72.0
DTH2_k127_6578481_0 KaiC - - - 0.0000000000000000000000000000000001018 142.0
DTH2_k127_6578481_1 - - - - 0.00000000000000000000000001364 122.0
DTH2_k127_6578481_2 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000003724 111.0
DTH2_k127_6681480_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 397.0
DTH2_k127_6681480_1 amino acid - - - 0.0000000000004529 75.0
DTH2_k127_681354_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 390.0
DTH2_k127_681354_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 321.0
DTH2_k127_681354_2 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000001962 251.0
DTH2_k127_681354_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000007674 198.0
DTH2_k127_681354_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000002924 188.0
DTH2_k127_681354_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000001185 187.0
DTH2_k127_681354_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000003287 116.0
DTH2_k127_681354_7 regulatory protein, arsR K03892 - - 0.0000000000003104 71.0
DTH2_k127_6818478_0 PFAM Molybdopterin guanine dinucleotide synthesis protein B K06947 - - 0.00000000000000000000000000000000000001446 158.0
DTH2_k127_6818478_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000002165 137.0
DTH2_k127_6818478_2 DNA repair protein K10880,K10958 GO:0000003,GO:0000150,GO:0000217,GO:0000280,GO:0000400,GO:0000707,GO:0000722,GO:0000723,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007127,GO:0007131,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0022414,GO:0022607,GO:0030491,GO:0032200,GO:0032991,GO:0033061,GO:0033062,GO:0033063,GO:0033170,GO:0033554,GO:0034622,GO:0034641,GO:0035825,GO:0035861,GO:0042148,GO:0042592,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0045003,GO:0046483,GO:0046982,GO:0046983,GO:0048285,GO:0050896,GO:0051276,GO:0051321,GO:0051716,GO:0060249,GO:0061982,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090734,GO:0090735,GO:0097159,GO:0140013,GO:0140097,GO:1901360,GO:1901363,GO:1903046 - 0.00000000000005392 81.0
DTH2_k127_6818478_3 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000004933 49.0
DTH2_k127_6818478_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000006696 52.0
DTH2_k127_684994_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 562.0
DTH2_k127_684994_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 484.0
DTH2_k127_684994_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 434.0
DTH2_k127_684994_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 353.0
DTH2_k127_684994_4 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001443 282.0
DTH2_k127_684994_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000001574 198.0
DTH2_k127_684994_6 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000003179 192.0
DTH2_k127_684994_7 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000001373 58.0
DTH2_k127_686590_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 596.0
DTH2_k127_686590_1 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002168 276.0
DTH2_k127_686590_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000595 251.0
DTH2_k127_686590_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000002672 246.0
DTH2_k127_686590_4 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000003146 233.0
DTH2_k127_686590_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000009073 199.0
DTH2_k127_686590_6 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000001362 194.0
DTH2_k127_686590_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000005092 139.0
DTH2_k127_686590_8 PFAM major facilitator superfamily MFS_1 - - - 0.00000000001627 75.0
DTH2_k127_686590_9 - - - - 0.000007034 51.0
DTH2_k127_6957089_0 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009419 255.0
DTH2_k127_6957089_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000003739 238.0
DTH2_k127_6957089_2 protoporphyrinogen oxidase activity K01854,K21779 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249,GO:0055114 5.4.99.9 0.00000000000008377 78.0
DTH2_k127_6957089_3 Dodecin K09165 - - 0.00000000004691 66.0
DTH2_k127_698979_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 401.0
DTH2_k127_698979_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 389.0
DTH2_k127_698979_10 Belongs to the eukaryotic ribosomal protein eL38 family K02923 - - 0.000005329 52.0
DTH2_k127_698979_11 ThiS family K03636 - - 0.00004694 49.0
DTH2_k127_698979_2 PAC2 family K07159 - - 0.00000000000000000000000000000000000008123 151.0
DTH2_k127_698979_3 PFAM PAC2 family K06869 - - 0.0000000000000000000000000000000009708 139.0
DTH2_k127_698979_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000009904 136.0
DTH2_k127_698979_5 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000000243 111.0
DTH2_k127_698979_6 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000002184 102.0
DTH2_k127_698979_7 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.00000000000001533 76.0
DTH2_k127_698979_8 protein, 4-oxalocrotonate tautomerase homolog K01821 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 0.0000000001824 64.0
DTH2_k127_698979_9 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000007223 59.0
DTH2_k127_7002926_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 307.0
DTH2_k127_7002926_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006362 266.0
DTH2_k127_7002926_2 PFAM extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000006476 237.0
DTH2_k127_7002926_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000001534 196.0
DTH2_k127_7002926_4 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000009583 196.0
DTH2_k127_7028199_0 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 2.347e-209 677.0
DTH2_k127_7028199_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 374.0
DTH2_k127_7028199_10 UPF0292 protein - - - 0.000000000666 66.0
DTH2_k127_7028199_11 nucleic acid binding protein containing the AN1-type Zn-finger K07059 - - 0.0000002572 61.0
DTH2_k127_7028199_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 346.0
DTH2_k127_7028199_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001847 255.0
DTH2_k127_7028199_4 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000003783 192.0
DTH2_k127_7028199_5 Peptidase M50 - - - 0.000000000000000000000000000000000003399 147.0
DTH2_k127_7028199_6 HD domain K07023 - - 0.00000000000000000000000000002657 124.0
DTH2_k127_7028199_7 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000004136 98.0
DTH2_k127_7028199_8 PFAM GCN5-related N-acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000006443 103.0
DTH2_k127_7028199_9 Prokaryotic homologs of the JAB domain K03030 - - 0.0000000002456 66.0
DTH2_k127_7051636_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 4.701e-194 614.0
DTH2_k127_7051636_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 610.0
DTH2_k127_7051636_10 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000001011 207.0
DTH2_k127_7051636_11 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000005492 184.0
DTH2_k127_7051636_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000065 114.0
DTH2_k127_7051636_13 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000007998 93.0
DTH2_k127_7051636_14 Lrp/AsnC ligand binding domain - - - 0.0000000000001684 73.0
DTH2_k127_7051636_15 GINS complex protein K09723 - - 0.0000000003465 68.0
DTH2_k127_7051636_2 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 586.0
DTH2_k127_7051636_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 561.0
DTH2_k127_7051636_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 439.0
DTH2_k127_7051636_5 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 403.0
DTH2_k127_7051636_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 401.0
DTH2_k127_7051636_7 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 319.0
DTH2_k127_7051636_8 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000003504 227.0
DTH2_k127_7051636_9 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000004619 222.0
DTH2_k127_7165894_0 DNA-dependent DNA replication - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 325.0
DTH2_k127_7165894_1 DNA integration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004717 263.0
DTH2_k127_7171716_0 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 349.0
DTH2_k127_7171716_1 Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000436 235.0
DTH2_k127_7171716_10 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000001139 118.0
DTH2_k127_7171716_11 transcriptional regulator K03892 - - 0.0000000000000001594 84.0
DTH2_k127_7171716_12 signal sequence binding - - - 0.000000000000007529 82.0
DTH2_k127_7171716_13 - - - - 0.000000000006382 71.0
DTH2_k127_7171716_14 RHS repeat-associated core domain - - - 0.00000000001718 75.0
DTH2_k127_7171716_15 cytochrome c biogenesis protein K06196 - - 0.00001466 55.0
DTH2_k127_7171716_2 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family - - - 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
DTH2_k127_7171716_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000003396 221.0
DTH2_k127_7171716_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000005064 205.0
DTH2_k127_7171716_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000002765 192.0
DTH2_k127_7171716_6 OsmC-like protein - - - 0.000000000000000000000000000000000000000002089 160.0
DTH2_k127_7171716_7 DGC domain - - - 0.0000000000000000000000000000000002932 135.0
DTH2_k127_7171716_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000004814 130.0
DTH2_k127_7171716_9 DGC domain - - - 0.000000000000000000000000002073 116.0
DTH2_k127_7219684_0 Phosphomethylpyrimidine kinase K00941,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 493.0
DTH2_k127_7219684_1 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 411.0
DTH2_k127_7219684_10 Glycosyl hydrolases family 18 K01183 - 3.2.1.14 0.0002994 52.0
DTH2_k127_7219684_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 302.0
DTH2_k127_7219684_3 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001748 274.0
DTH2_k127_7219684_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000004793 185.0
DTH2_k127_7219684_5 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.00000000000000000000000000000000000000000004179 170.0
DTH2_k127_7219684_6 Glycosyl transferase family group 2 - - - 0.000000000000000009087 96.0
DTH2_k127_7219684_7 protein transport - - - 0.0000000000000001197 83.0
DTH2_k127_7219684_8 - - - - 0.00000008084 56.0
DTH2_k127_7219684_9 - - - - 0.000009376 56.0
DTH2_k127_7246164_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 508.0
DTH2_k127_7246164_1 Lysine biosynthesis K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 288.0
DTH2_k127_7246164_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001739 159.0
DTH2_k127_7246164_3 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000001016 146.0
DTH2_k127_7246164_4 lysine biosynthesis protein LysW K05826 - - 0.00000000000001168 76.0
DTH2_k127_7246164_5 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000004067 64.0
DTH2_k127_7262021_0 Glycosyltransferase like family 2 - - - 0.000000001068 65.0
DTH2_k127_7263487_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.119e-268 855.0
DTH2_k127_7263487_1 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 458.0
DTH2_k127_7263487_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 437.0
DTH2_k127_7263487_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 403.0
DTH2_k127_7263487_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 404.0
DTH2_k127_7263487_5 Acyl-CoA synthetase (NDP forming) K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 332.0
DTH2_k127_7263487_6 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000008063 127.0
DTH2_k127_7263487_7 PFAM peptidase U32 K08303 - - 0.00000000000000001564 84.0
DTH2_k127_7335850_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 9.492e-197 623.0
DTH2_k127_7335850_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 557.0
DTH2_k127_7335850_10 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008662 252.0
DTH2_k127_7335850_11 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000001976 183.0
DTH2_k127_7335850_12 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000003555 176.0
DTH2_k127_7335850_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000009981 157.0
DTH2_k127_7335850_14 Conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000714 155.0
DTH2_k127_7335850_15 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.00000000000000000000000000000000000002004 150.0
DTH2_k127_7335850_16 Conserved protein implicated in secretion - - - 0.00000000000000000000000000003182 124.0
DTH2_k127_7335850_17 ribosomal protein K02976 - - 0.0000000000000000000000000004646 115.0
DTH2_k127_7335850_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000002527 119.0
DTH2_k127_7335850_19 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000001122 113.0
DTH2_k127_7335850_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 542.0
DTH2_k127_7335850_20 Conserved protein implicated in secretion - - - 0.0000000000000000000000006943 114.0
DTH2_k127_7335850_21 - - - - 0.000000000000000000005451 100.0
DTH2_k127_7335850_22 FtsZ-dependent cytokinesis - - - 0.0000000000000000005722 94.0
DTH2_k127_7335850_23 - - - - 0.00000000000000001615 91.0
DTH2_k127_7335850_24 - - - - 0.00000000003807 70.0
DTH2_k127_7335850_25 - - - - 0.00000000004237 65.0
DTH2_k127_7335850_26 transcriptional K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000009634 57.0
DTH2_k127_7335850_3 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 403.0
DTH2_k127_7335850_4 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 399.0
DTH2_k127_7335850_5 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 339.0
DTH2_k127_7335850_6 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 303.0
DTH2_k127_7335850_7 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 295.0
DTH2_k127_7335850_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000468 288.0
DTH2_k127_7335850_9 Mn2 dependent serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006546 265.0
DTH2_k127_7428149_0 MULE transposase domain - - - 0.000000000000000000000000000000000000000000000000000000008984 203.0
DTH2_k127_7428149_1 Transposase, Mutator family - - - 0.00000000000000000000000001007 110.0
DTH2_k127_7428149_2 MULE transposase domain - - - 0.00000000000000001074 84.0
DTH2_k127_7430152_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 475.0
DTH2_k127_7430152_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 354.0
DTH2_k127_7430152_2 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000000000000000000000004204 185.0
DTH2_k127_7430152_3 SMART Nucleotide binding protein, PINc K07158 - - 0.0000000000000000000193 96.0
DTH2_k127_7430152_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000001094 67.0
DTH2_k127_751004_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000004979 121.0
DTH2_k127_751004_1 zinc-ribbon domain - - - 0.00000000933 66.0
DTH2_k127_7522943_0 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 314.0
DTH2_k127_7522943_1 Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001969 269.0
DTH2_k127_7522943_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000264 250.0
DTH2_k127_7522943_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000006496 157.0
DTH2_k127_7556753_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 404.0
DTH2_k127_7556753_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000002627 238.0
DTH2_k127_7556753_2 Interconversion of serine and glycine K00600 GO:0000900,GO:0001101,GO:0001505,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004372,GO:0004793,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006144,GO:0006220,GO:0006221,GO:0006231,GO:0006417,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006565,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007610,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008732,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009437,GO:0009636,GO:0009719,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0014070,GO:0016043,GO:0016053,GO:0016054,GO:0016597,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0017148,GO:0018130,GO:0019222,GO:0019264,GO:0019438,GO:0019637,GO:0019692,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0030371,GO:0030534,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0034097,GO:0034248,GO:0034249,GO:0034641,GO:0034654,GO:0035999,GO:0036094,GO:0042133,GO:0042136,GO:0042221,GO:0042398,GO:0042440,GO:0042493,GO:0042558,GO:0042752,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045329,GO:0045471,GO:0046073,GO:0046112,GO:0046148,GO:0046385,GO:0046394,GO:0046395,GO:0046483,GO:0046653,GO:0046655,GO:0046677,GO:0046983,GO:0048027,GO:0048037,GO:0048149,GO:0048519,GO:0048523,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051186,GO:0051246,GO:0051248,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055086,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070279,GO:0070887,GO:0070905,GO:0071229,GO:0071310,GO:0071345,GO:0071407,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0080090,GO:0090079,GO:0090407,GO:0097159,GO:0097164,GO:0097305,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1904481,GO:1904482,GO:1990823,GO:1990830,GO:2000112,GO:2000113 2.1.2.1 0.0000000000000000000000000004236 114.0
DTH2_k127_7556753_3 Mut7-C ubiquitin - - - 0.000000003114 61.0
DTH2_k127_7556753_4 PFAM ThiamineS - - - 0.0001065 48.0
DTH2_k127_7587835_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 5.851e-196 629.0
DTH2_k127_7587835_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000007394 106.0
DTH2_k127_7587835_2 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000003143 109.0
DTH2_k127_7587835_3 Methionyl-tRNA synthetase, beta subunit K06878 - - 0.00000000000001898 78.0
DTH2_k127_7587835_4 TIGRFAM MoaD family protein K03636 - - 0.000004038 52.0
DTH2_k127_7594724_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.773e-320 998.0
DTH2_k127_7594724_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 402.0
DTH2_k127_7594724_2 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 295.0
DTH2_k127_7594724_3 YHS domain - - - 0.0000000000003062 70.0
DTH2_k127_7635832_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.75e-285 900.0
DTH2_k127_7635832_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 7.485e-198 629.0
DTH2_k127_7635832_10 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001563 276.0
DTH2_k127_7635832_11 50S ribosomal protein L4 K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001587 258.0
DTH2_k127_7635832_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005272 253.0
DTH2_k127_7635832_13 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004445 230.0
DTH2_k127_7635832_14 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000000000000008427 197.0
DTH2_k127_7635832_15 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000002083 191.0
DTH2_k127_7635832_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000969 163.0
DTH2_k127_7635832_17 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000002834 155.0
DTH2_k127_7635832_18 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000005541 154.0
DTH2_k127_7635832_19 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000002014 134.0
DTH2_k127_7635832_2 tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 8.868e-197 624.0
DTH2_k127_7635832_20 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.0000000000000000000000000002761 121.0
DTH2_k127_7635832_21 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000002347 112.0
DTH2_k127_7635832_22 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000165 102.0
DTH2_k127_7635832_23 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000004032 87.0
DTH2_k127_7635832_24 regulatory protein, arsR - - - 0.000000000007302 70.0
DTH2_k127_7635832_25 CAAX protease self-immunity - - - 0.00000000004797 74.0
DTH2_k127_7635832_26 chromosome segregation - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0051186,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0106035,GO:1901564 - 0.00000000005586 67.0
DTH2_k127_7635832_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000003141 53.0
DTH2_k127_7635832_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 482.0
DTH2_k127_7635832_4 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 486.0
DTH2_k127_7635832_5 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 456.0
DTH2_k127_7635832_6 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 434.0
DTH2_k127_7635832_7 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0043774,GO:0044424,GO:0044464 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 366.0
DTH2_k127_7635832_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 308.0
DTH2_k127_7635832_9 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 301.0
DTH2_k127_7648215_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 7.58e-199 636.0
DTH2_k127_7648215_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 327.0
DTH2_k127_7648215_2 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000002503 230.0
DTH2_k127_7648215_3 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000001601 213.0
DTH2_k127_7648215_4 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000001371 151.0
DTH2_k127_772632_0 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 304.0
DTH2_k127_772632_1 Homocitrate synthase K01649 - 2.3.3.13 0.000000000000000000000000000006972 121.0
DTH2_k127_772632_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.000000000000000000000000003871 114.0
DTH2_k127_7766937_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 243.0
DTH2_k127_7766937_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000005965 192.0
DTH2_k127_7766937_2 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000005784 168.0
DTH2_k127_7766937_3 glucosylceramidase activity - - - 0.0006633 47.0
DTH2_k127_7778258_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 6.543e-195 622.0
DTH2_k127_7778258_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 342.0
DTH2_k127_7778258_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000008681 228.0
DTH2_k127_7778258_3 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000004055 194.0
DTH2_k127_7778258_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000001898 181.0
DTH2_k127_7778258_5 protein secretion by the type IV secretion system - - - 0.0000000000000000000000000382 127.0
DTH2_k127_7778258_6 Transcriptional regulator K09714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000009761 65.0
DTH2_k127_7778258_7 - - - - 0.0000004132 64.0
DTH2_k127_7849059_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000009109 251.0
DTH2_k127_7849059_1 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000002886 233.0
DTH2_k127_7849059_3 - - - - 0.000000000000000000009001 100.0
DTH2_k127_7849059_4 Domain of unknown function (DUF1508) K09946 - - 0.0000000000000000016 86.0
DTH2_k127_7849059_5 Immune inhibitor A peptidase M6 K09607 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.000001719 57.0
DTH2_k127_7849059_6 F420H(2)-dependent quinone reductase - - - 0.000004869 49.0
DTH2_k127_7849059_7 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.00007828 46.0
DTH2_k127_7849059_8 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.0006973 45.0
DTH2_k127_787775_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 416.0
DTH2_k127_787775_1 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000001383 168.0
DTH2_k127_7934474_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 340.0
DTH2_k127_7934474_1 Chlorophyllase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
DTH2_k127_7934474_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006131 249.0
DTH2_k127_7934474_3 - - - - 0.0000000000000000000000000000000001897 142.0
DTH2_k127_7934474_4 ADP-ribose pyrophosphatase K03574 - 3.6.1.55 0.00000000000000000000000002718 112.0
DTH2_k127_7934474_5 Transcriptional regulator K02019,K05772 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000003059 83.0
DTH2_k127_7934474_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000003361 83.0
DTH2_k127_7934474_7 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768,K07151 - 2.4.99.18,5.2.1.8 0.0000000004757 72.0
DTH2_k127_7934474_8 Uncharacterized protein family UPF0016 - - - 0.000000007125 58.0
DTH2_k127_7934474_9 Psort location Cytoplasmic, score - - - 0.000000306 64.0
DTH2_k127_7980360_0 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 543.0
DTH2_k127_7980360_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 321.0
DTH2_k127_7980360_2 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001152 262.0
DTH2_k127_7980360_3 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002319 246.0
DTH2_k127_7980360_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
DTH2_k127_7980360_5 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000001494 179.0
DTH2_k127_7980360_6 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000003841 94.0
DTH2_k127_7980360_7 resolution of meiotic recombination intermediates - - - 0.0000000000000003216 85.0
DTH2_k127_7980360_8 Nitroreductase - - - 0.0000000000002309 71.0
DTH2_k127_7991166_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 452.0
DTH2_k127_7991166_1 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005306 250.0
DTH2_k127_7991166_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000002127 209.0
DTH2_k127_7991166_3 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000006242 182.0
DTH2_k127_7991166_4 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000003112 171.0
DTH2_k127_7991166_5 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000001223 174.0
DTH2_k127_7991166_6 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.000000000000000000000004331 117.0
DTH2_k127_7991166_7 Putative Phosphatase K01079 - 3.1.3.3 0.0000000000000528 80.0
DTH2_k127_8020797_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1196.0
DTH2_k127_8020797_1 nucleotide-excision repair K03702,K08999 - - 3.181e-260 818.0
DTH2_k127_8020797_10 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 303.0
DTH2_k127_8020797_11 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 295.0
DTH2_k127_8020797_12 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 285.0
DTH2_k127_8020797_13 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009916 279.0
DTH2_k127_8020797_14 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 274.0
DTH2_k127_8020797_15 Chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001537 283.0
DTH2_k127_8020797_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 267.0
DTH2_k127_8020797_17 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000004081 211.0
DTH2_k127_8020797_18 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000001159 211.0
DTH2_k127_8020797_19 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000000000000000000000000003471 189.0
DTH2_k127_8020797_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 496.0
DTH2_k127_8020797_20 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000005254 167.0
DTH2_k127_8020797_21 peptidase - - - 0.000000000000000000000000000000000000002297 156.0
DTH2_k127_8020797_22 hydrolase (HAD superfamily) K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000002181 153.0
DTH2_k127_8020797_23 Thioredoxin K03671 - - 0.000000000000000000000000000000000001563 142.0
DTH2_k127_8020797_24 OsmC-like protein - - - 0.000000000000000000000000000000000001748 144.0
DTH2_k127_8020797_25 NUDIX domain - - - 0.0000000000000000000000000000000001321 139.0
DTH2_k127_8020797_26 OsmC-like protein K09136 - - 0.000000000000000000000000001763 115.0
DTH2_k127_8020797_27 Deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.000000000000000000000000006265 115.0
DTH2_k127_8020797_28 transcriptional - - - 0.0000000000000000000000000103 113.0
DTH2_k127_8020797_29 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000272 106.0
DTH2_k127_8020797_3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 484.0
DTH2_k127_8020797_30 Nitroreductase family K10678,K19285 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016651,GO:0016657,GO:0032553,GO:0034567,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.38 0.0000000000000000000003653 106.0
DTH2_k127_8020797_31 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000001207 102.0
DTH2_k127_8020797_32 Thioredoxin - - - 0.00000000000000000000288 97.0
DTH2_k127_8020797_33 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000004595 97.0
DTH2_k127_8020797_34 Alkaline and neutral invertase - - - 0.0000000000001099 82.0
DTH2_k127_8020797_35 - - - - 0.00000000000131 71.0
DTH2_k127_8020797_36 Major facilitator - - - 0.00000000001789 76.0
DTH2_k127_8020797_37 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.0000000009636 63.0
DTH2_k127_8020797_38 membrane protein (DUF2078) K08982 - - 0.000000122 59.0
DTH2_k127_8020797_39 transferase activity, transferring glycosyl groups - - - 0.000009414 53.0
DTH2_k127_8020797_4 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 466.0
DTH2_k127_8020797_40 membrane protein (DUF2078) K08982 - - 0.0002197 47.0
DTH2_k127_8020797_5 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 443.0
DTH2_k127_8020797_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 403.0
DTH2_k127_8020797_7 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 379.0
DTH2_k127_8020797_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
DTH2_k127_8020797_9 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 313.0
DTH2_k127_8030337_0 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 305.0
DTH2_k127_8030337_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000532 252.0
DTH2_k127_8030337_2 - - - - 0.0000000007452 70.0
DTH2_k127_8060355_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000004512 243.0
DTH2_k127_8060355_1 CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000001144 189.0
DTH2_k127_8060355_2 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000003354 97.0
DTH2_k127_8060355_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000002317 67.0
DTH2_k127_8311911_0 PrkA AAA domain K07180 - - 2.818e-273 856.0
DTH2_k127_8311911_1 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 396.0
DTH2_k127_8311911_2 PrkA serine protein kinase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006301 289.0
DTH2_k127_8363643_0 COG3256 Nitric oxide reductase large subunit K04561 - 1.7.2.5 2.614e-277 859.0
DTH2_k127_8363643_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 365.0
DTH2_k127_8363643_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 293.0
DTH2_k127_8363643_3 Histidine Phosphotransfer domain K03413,K07662,K07667,K11443 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008365 271.0
DTH2_k127_8363643_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000005249 177.0
DTH2_k127_8363643_5 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000001368 137.0
DTH2_k127_8399854_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.852e-242 762.0
DTH2_k127_8399854_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.125e-226 707.0
DTH2_k127_8399854_10 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000009786 190.0
DTH2_k127_8399854_11 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000002955 203.0
DTH2_k127_8399854_12 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000000004662 166.0
DTH2_k127_8399854_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000007332 158.0
DTH2_k127_8399854_14 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000008935 154.0
DTH2_k127_8399854_15 Uncharacterized protein conserved in archaea (DUF2110) - - - 0.00000000000000000000000000000000008132 143.0
DTH2_k127_8399854_16 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000002398 143.0
DTH2_k127_8399854_17 PUA domain containing protein K07398 - - 0.0000000000000000000000000000001607 129.0
DTH2_k127_8399854_18 Protein of unknown function (DUF4013) - - - 0.0000000000000000000000000008673 122.0
DTH2_k127_8399854_19 Rubredoxin - - - 0.000000000000000000003342 93.0
DTH2_k127_8399854_2 isocitrate K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 490.0
DTH2_k127_8399854_20 Helix-turn-helix domain protein K03627 - - 0.0000000000000000001274 95.0
DTH2_k127_8399854_21 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K18358,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.1.58,1.2.7.1,1.2.7.10 0.0000000000001418 72.0
DTH2_k127_8399854_22 PFAM 4Fe-4S ferredoxin - - - 0.0000000000005864 70.0
DTH2_k127_8399854_23 Subtilase family - - - 0.0000000001636 74.0
DTH2_k127_8399854_24 Transcriptional regulator K22206 - - 0.00000001873 62.0
DTH2_k127_8399854_25 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000003122 55.0
DTH2_k127_8399854_26 UPF0210 protein K09157 - - 0.0004308 46.0
DTH2_k127_8399854_3 amidohydrolase K21613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 369.0
DTH2_k127_8399854_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 358.0
DTH2_k127_8399854_5 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 354.0
DTH2_k127_8399854_6 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
DTH2_k127_8399854_7 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004572 280.0
DTH2_k127_8399854_8 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000004399 192.0
DTH2_k127_8399854_9 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000004826 192.0
DTH2_k127_8502258_0 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 319.0
DTH2_k127_8502258_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000003807 242.0
DTH2_k127_8502258_2 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000002797 184.0
DTH2_k127_8502258_3 Peptidase family M28 K19702 - 3.4.11.24 0.0000000000000002219 93.0
DTH2_k127_8502258_4 ECF-type riboflavin transporter, S component - - - 0.00000001057 64.0
DTH2_k127_8502258_5 DinB family - - - 0.00000003465 63.0
DTH2_k127_8502258_6 - - - - 0.0000001376 61.0
DTH2_k127_8503385_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000006505 210.0
DTH2_k127_8503385_1 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000003632 200.0
DTH2_k127_8503385_2 - - - - 0.0000000000000000000000000000000003128 142.0
DTH2_k127_8503385_3 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000001944 125.0
DTH2_k127_8524775_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 510.0
DTH2_k127_8524775_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002342 168.0
DTH2_k127_8524775_2 4Fe-4S binding domain - - - 0.0000000000000000000000000002845 126.0
DTH2_k127_8524775_3 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000001661 90.0
DTH2_k127_8590449_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 480.0
DTH2_k127_8590449_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 292.0
DTH2_k127_8590449_2 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000337 253.0
DTH2_k127_8590449_3 RNase H K03469 - 3.1.26.4 0.00000000000004205 77.0
DTH2_k127_8590449_4 ATP binding protein K06883 - - 0.000000000001744 71.0
DTH2_k127_8590449_5 archaeal coiled-coil protein - - - 0.0000000001058 72.0
DTH2_k127_8595729_0 metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 436.0
DTH2_k127_8595729_1 TIGRFAM DNA helicase - - - 0.0000000000000000000000000000000000000000000000000000006455 219.0
DTH2_k127_8595729_2 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000001784 119.0
DTH2_k127_8667687_0 Belongs to the glutamate synthase family - - - 6.221e-229 720.0
DTH2_k127_8667687_1 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 496.0
DTH2_k127_8667687_2 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003749 257.0
DTH2_k127_8667687_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001257 248.0
DTH2_k127_8813282_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 405.0
DTH2_k127_8813282_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000001566 215.0
DTH2_k127_8813282_2 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000008476 205.0
DTH2_k127_8813282_3 - - - - 0.00000000000000000000000000000009792 128.0
DTH2_k127_8813282_4 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000001723 82.0
DTH2_k127_8920406_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000002522 129.0
DTH2_k127_8920406_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000006737 103.0
DTH2_k127_8947171_0 Lysine biosynthesis K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000001085 261.0
DTH2_k127_8947171_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
DTH2_k127_8947171_2 lysine biosynthesis protein LysW K05826 - - 0.00000000002421 65.0
DTH2_k127_895475_0 small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 436.0
DTH2_k127_895475_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 294.0
DTH2_k127_895475_2 Exonuclease RNase T and DNA polymerase III - - - 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
DTH2_k127_895475_3 flavin reductase - - - 0.000000000000000000000000000000000000000000000000000000000003839 213.0
DTH2_k127_895475_4 PFAM Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000002304 212.0
DTH2_k127_895475_5 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000002425 188.0
DTH2_k127_895475_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000204 161.0
DTH2_k127_895475_7 PFAM Rhomboid family protein K07059 - - 0.00000000000000000000000000000000003265 142.0
DTH2_k127_895475_8 - - - - 0.00000000000000000000001069 104.0
DTH2_k127_895475_9 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000002171 89.0
DTH2_k127_9095508_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 485.0
DTH2_k127_9176905_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 258.0
DTH2_k127_9176905_1 PFAM extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000001706 142.0
DTH2_k127_9176905_2 ABC-2 family transporter protein - - - 0.000000000000000000000000000000001134 135.0
DTH2_k127_9222483_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001045 235.0
DTH2_k127_9222483_1 Acetamidase/Formamidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000006911 192.0
DTH2_k127_9250981_0 Cation transporter/ATPase, N-terminus - - - 2.159e-284 901.0
DTH2_k127_9250981_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 370.0
DTH2_k127_9250981_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002607 266.0
DTH2_k127_9250981_3 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001488 269.0
DTH2_k127_9250981_4 domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000004268 205.0
DTH2_k127_9250981_5 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000001391 111.0
DTH2_k127_9250981_6 lactoylglutathione lyase activity K01239,K08234 - 3.2.2.1 0.0000006707 57.0
DTH2_k127_9256286_0 PFAM Fmu (Sun) domain protein K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003336 282.0
DTH2_k127_9256286_1 - - - - 0.000000000000000000000000000000000000000000000000000901 192.0
DTH2_k127_9256286_2 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000005322 189.0
DTH2_k127_9256286_3 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000002615 178.0
DTH2_k127_9256286_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000004424 154.0
DTH2_k127_9256286_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.0000000000000000000000002984 111.0
DTH2_k127_9256286_6 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000007142 101.0
DTH2_k127_9256286_7 Radical SAM domain protein - - - 0.000000005973 57.0
DTH2_k127_9297057_0 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 349.0
DTH2_k127_9297057_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000000005609 159.0
DTH2_k127_9297057_2 Isochorismatase family - - - 0.000000000000000000000000000000000000009484 151.0
DTH2_k127_9297057_3 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000003846 121.0
DTH2_k127_9297057_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000000001115 84.0
DTH2_k127_9297057_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000001759 63.0
DTH2_k127_9360212_0 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000001312 208.0
DTH2_k127_9360212_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000005998 137.0
DTH2_k127_9360212_2 Serine threonine protein kinase - - - 0.00000000000000000000000000001002 132.0
DTH2_k127_9360212_3 serine threonine protein kinase K00870 - 2.7.1.37 0.0000000000000001539 90.0
DTH2_k127_9360212_4 Zinc finger domain - - - 0.00000165 57.0
DTH2_k127_9388908_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1293.0
DTH2_k127_9388908_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 466.0
DTH2_k127_9388908_10 4Fe-4S binding domain protein - - - 0.000000000000000000000002389 105.0
DTH2_k127_9388908_11 Cupin domain - - - 0.000000000000002318 80.0
DTH2_k127_9388908_12 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000005507 66.0
DTH2_k127_9388908_13 - - - - 0.000003044 58.0
DTH2_k127_9388908_2 TIGRFAM dihydroorotate dehydrogenase family protein K00226,K17723 - 1.3.1.1,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 341.0
DTH2_k127_9388908_3 COG0607 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 332.0
DTH2_k127_9388908_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000642 224.0
DTH2_k127_9388908_5 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000001608 184.0
DTH2_k127_9388908_6 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000001191 163.0
DTH2_k127_9388908_7 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000004723 159.0
DTH2_k127_9388908_8 NAD(P)H dehydrogenase (quinone) activity - - - 0.00000000000000000000000000000000001409 141.0
DTH2_k127_9388908_9 TfoX N-terminal domain - - - 0.000000000000000000000000001803 115.0
DTH2_k127_9465492_0 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0008964,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0071704 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 506.0
DTH2_k127_9465492_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 327.0
DTH2_k127_9465492_10 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.000000000000000000000000000000000000000000000001916 181.0
DTH2_k127_9465492_11 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000001614 165.0
DTH2_k127_9465492_12 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000000000000000000000000000000001105 161.0
DTH2_k127_9465492_13 PFAM Translin K07477 - - 0.000000000000000000000000000001188 129.0
DTH2_k127_9465492_14 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000001574 111.0
DTH2_k127_9465492_15 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000002799 109.0
DTH2_k127_9465492_16 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000004604 91.0
DTH2_k127_9465492_17 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.000000000004961 69.0
DTH2_k127_9465492_18 Belongs to the UPF0248 family K09715 - - 0.000000000145 64.0
DTH2_k127_9465492_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 290.0
DTH2_k127_9465492_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002879 280.0
DTH2_k127_9465492_4 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004531 261.0
DTH2_k127_9465492_5 ERCC4 domain K10896 - - 0.000000000000000000000000000000000000000000000000000000000000000000001351 248.0
DTH2_k127_9465492_6 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000005051 237.0
DTH2_k127_9465492_7 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000001123 219.0
DTH2_k127_9465492_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000001406 207.0
DTH2_k127_9465492_9 nicotinamide-nucleotide adenylyltransferase K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000478 186.0
DTH2_k127_9494921_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000001852 211.0
DTH2_k127_9494921_1 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000001231 198.0
DTH2_k127_9494921_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000622 180.0
DTH2_k127_9494921_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000007082 177.0
DTH2_k127_9494921_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005692 171.0
DTH2_k127_9494921_5 Psort location Cytoplasmic, score K00008 - 1.1.1.14 0.000000000000000000000000000000000002748 151.0
DTH2_k127_9494921_6 Uncharacterized protein conserved in bacteria (DUF2064) - - - 0.000000000000000499 87.0
DTH2_k127_9494921_7 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - 0.0000000000003774 81.0
DTH2_k127_9516548_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 460.0
DTH2_k127_9516548_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 332.0
DTH2_k127_9516548_2 Serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000003901 234.0
DTH2_k127_9516548_3 SMART KH domain protein K06961 - - 0.0000000000000000000000000000000000000000002341 164.0
DTH2_k127_9516548_4 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000001372 117.0
DTH2_k127_9516548_5 Protein of unknown function (DUF424) K09148 - - 0.000000000000000008327 85.0
DTH2_k127_9601139_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 360.0
DTH2_k127_9601139_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000002742 257.0
DTH2_k127_9601139_2 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000001021 174.0
DTH2_k127_9601139_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000008654 88.0
DTH2_k127_9601139_4 AsnC family - - - 0.00000003565 57.0
DTH2_k127_9601139_5 PFAM regulatory protein AsnC Lrp family - - - 0.00005842 50.0
DTH2_k127_9673395_0 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 417.0
DTH2_k127_9673395_1 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000003325 247.0
DTH2_k127_9673395_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000007001 218.0
DTH2_k127_9673395_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000007796 174.0
DTH2_k127_9830340_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 505.0
DTH2_k127_9830340_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 468.0
DTH2_k127_9830340_2 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 342.0
DTH2_k127_9830340_3 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001521 277.0
DTH2_k127_9830340_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000008137 221.0
DTH2_k127_9830340_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000004791 198.0
DTH2_k127_9830340_6 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000005455 137.0
DTH2_k127_9830340_7 PFAM Peptidase S53, propeptide - - - 0.00000000000000000004806 102.0
DTH2_k127_9830340_8 Belongs to the ubiquitin-conjugating enzyme family K10583 - 2.3.2.23 0.0000000001611 69.0
DTH2_k127_9830340_9 Right handed beta helix region - - - 0.000001815 61.0
DTH2_k127_9932488_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 596.0
DTH2_k127_9932488_1 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 426.0
DTH2_k127_9932488_10 PFAM MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000174 130.0
DTH2_k127_9932488_11 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000351 114.0
DTH2_k127_9932488_12 Belongs to the RecA family K10872,K14545 GO:0000003,GO:0000018,GO:0000150,GO:0000166,GO:0000217,GO:0000228,GO:0000280,GO:0000400,GO:0000709,GO:0000724,GO:0000725,GO:0000730,GO:0000793,GO:0000794,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006311,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007129,GO:0007130,GO:0007131,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010520,GO:0010564,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0022607,GO:0030554,GO:0031323,GO:0031974,GO:0031981,GO:0032553,GO:0032555,GO:0032559,GO:0033043,GO:0033554,GO:0034622,GO:0034641,GO:0035639,GO:0035822,GO:0035825,GO:0036094,GO:0040020,GO:0042148,GO:0042623,GO:0042802,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044877,GO:0045003,GO:0045132,GO:0045143,GO:0046483,GO:0048285,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051128,GO:0051171,GO:0051259,GO:0051260,GO:0051276,GO:0051321,GO:0051445,GO:0051716,GO:0051726,GO:0051783,GO:0060255,GO:0060631,GO:0061982,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070192,GO:0070193,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090735,GO:0097159,GO:0097367,GO:0098813,GO:0140013,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1903046,GO:1905334,GO:2000241 - 0.0000000653 63.0
DTH2_k127_9932488_13 - - - - 0.0000008974 54.0
DTH2_k127_9932488_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 325.0
DTH2_k127_9932488_3 secondary active sulfate transmembrane transporter activity K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005521 272.0
DTH2_k127_9932488_4 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001864 271.0
DTH2_k127_9932488_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000004822 239.0
DTH2_k127_9932488_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000002487 233.0
DTH2_k127_9932488_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000001737 187.0
DTH2_k127_9932488_9 TIGRFAM archaeoflavoprotein AfpA - - - 0.0000000000000000000000000000000000000000000006076 171.0