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Overview

ID MAG00792
Name DTH2_bin.72
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family
Genus
Species
Assembly information
Completeness (%) 95.07
Contamination (%) 0.73
GC content (%) 58.0
N50 (bp) 15,249
Genome size (bp) 2,243,147

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2120

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_110979_0 Protein conserved in bacteria - - - 5.415e-241 770.0
DTH2_k127_110979_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 591.0
DTH2_k127_110979_2 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009327 266.0
DTH2_k127_110979_3 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000293 228.0
DTH2_k127_110979_4 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000002518 188.0
DTH2_k127_110979_5 Diadenylate cyclase - - - 0.0000000000000000000000000000000000000000001767 170.0
DTH2_k127_110979_6 Protein of unknown function DUF72 - - - 0.0001341 45.0
DTH2_k127_111670_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.018e-206 649.0
DTH2_k127_111670_1 Nitroreductase - - - 6.556e-202 643.0
DTH2_k127_111670_10 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
DTH2_k127_111670_11 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001333 263.0
DTH2_k127_111670_12 Belongs to the acetokinase family K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000001152 272.0
DTH2_k127_111670_13 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000007671 234.0
DTH2_k127_111670_14 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000003412 213.0
DTH2_k127_111670_15 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000001321 201.0
DTH2_k127_111670_16 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000009078 173.0
DTH2_k127_111670_17 Domain of unknown function (DUF4214) - - - 0.0000000000000000001142 97.0
DTH2_k127_111670_2 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 8.819e-198 632.0
DTH2_k127_111670_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 510.0
DTH2_k127_111670_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 496.0
DTH2_k127_111670_5 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 401.0
DTH2_k127_111670_6 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 393.0
DTH2_k127_111670_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 302.0
DTH2_k127_111670_8 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 300.0
DTH2_k127_111670_9 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008755 278.0
DTH2_k127_1289015_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1517.0
DTH2_k127_1289015_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.559e-265 832.0
DTH2_k127_1289015_10 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000001052 233.0
DTH2_k127_1289015_11 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000001403 238.0
DTH2_k127_1289015_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000004509 200.0
DTH2_k127_1289015_13 Bacterial regulatory protein, Fis family K02667 - - 0.000000000000000000000000000000003724 134.0
DTH2_k127_1289015_14 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000005532 125.0
DTH2_k127_1289015_15 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000005818 125.0
DTH2_k127_1289015_16 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000005707 97.0
DTH2_k127_1289015_17 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000247 85.0
DTH2_k127_1289015_18 Regulatory protein, FmdB family - - - 0.000000000003094 68.0
DTH2_k127_1289015_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 603.0
DTH2_k127_1289015_20 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000003388 55.0
DTH2_k127_1289015_21 PFAM response regulator receiver - - - 0.0000166 49.0
DTH2_k127_1289015_22 - - - - 0.00006711 46.0
DTH2_k127_1289015_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 317.0
DTH2_k127_1289015_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 301.0
DTH2_k127_1289015_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
DTH2_k127_1289015_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000005348 263.0
DTH2_k127_1289015_7 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 267.0
DTH2_k127_1289015_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002066 250.0
DTH2_k127_1289015_9 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000002217 240.0
DTH2_k127_1294591_0 Endoribonuclease that initiates mRNA decay K18682 - - 5.608e-218 687.0
DTH2_k127_1294591_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 430.0
DTH2_k127_1294591_10 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000000216 123.0
DTH2_k127_1294591_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000005344 116.0
DTH2_k127_1294591_2 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 364.0
DTH2_k127_1294591_3 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 350.0
DTH2_k127_1294591_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
DTH2_k127_1294591_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 316.0
DTH2_k127_1294591_6 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 290.0
DTH2_k127_1294591_7 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 274.0
DTH2_k127_1294591_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000004105 217.0
DTH2_k127_1294591_9 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000002668 187.0
DTH2_k127_1306444_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 4.964e-215 678.0
DTH2_k127_1306444_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.337e-206 650.0
DTH2_k127_1306444_10 PFAM Sulphate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 286.0
DTH2_k127_1306444_11 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
DTH2_k127_1306444_12 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000002033 246.0
DTH2_k127_1306444_13 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000001153 232.0
DTH2_k127_1306444_14 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000001266 220.0
DTH2_k127_1306444_15 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000001099 211.0
DTH2_k127_1306444_16 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000009172 198.0
DTH2_k127_1306444_17 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000004462 182.0
DTH2_k127_1306444_18 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000264 173.0
DTH2_k127_1306444_19 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000004883 152.0
DTH2_k127_1306444_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 553.0
DTH2_k127_1306444_20 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000009171 145.0
DTH2_k127_1306444_21 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000002119 138.0
DTH2_k127_1306444_22 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000001051 115.0
DTH2_k127_1306444_23 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001195 110.0
DTH2_k127_1306444_24 Belongs to the UPF0235 family K09131 - - 0.0000000000000006047 81.0
DTH2_k127_1306444_25 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000001004 57.0
DTH2_k127_1306444_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 518.0
DTH2_k127_1306444_4 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 395.0
DTH2_k127_1306444_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 381.0
DTH2_k127_1306444_6 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 313.0
DTH2_k127_1306444_7 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 297.0
DTH2_k127_1306444_8 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 293.0
DTH2_k127_1306444_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000209 281.0
DTH2_k127_1361358_0 Dehydratase family K01687 - 4.2.1.9 3.89e-268 834.0
DTH2_k127_1361358_1 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.039e-212 672.0
DTH2_k127_1361358_10 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 351.0
DTH2_k127_1361358_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002378 273.0
DTH2_k127_1361358_12 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007757 248.0
DTH2_k127_1361358_13 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000026 216.0
DTH2_k127_1361358_14 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000147 191.0
DTH2_k127_1361358_15 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000004641 181.0
DTH2_k127_1361358_16 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000002774 184.0
DTH2_k127_1361358_17 HDOD domain - - - 0.000000000000000000000000000000000000000000000004271 182.0
DTH2_k127_1361358_18 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000002101 104.0
DTH2_k127_1361358_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 479.0
DTH2_k127_1361358_20 Histidine kinase K01769,K11959 - 4.6.1.2 0.0000002278 61.0
DTH2_k127_1361358_21 - - - - 0.00002358 49.0
DTH2_k127_1361358_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 462.0
DTH2_k127_1361358_4 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 441.0
DTH2_k127_1361358_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 438.0
DTH2_k127_1361358_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 412.0
DTH2_k127_1361358_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 406.0
DTH2_k127_1361358_8 response regulator receiver K02481,K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 378.0
DTH2_k127_1361358_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 356.0
DTH2_k127_1396364_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1142.0
DTH2_k127_1396364_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.06e-225 706.0
DTH2_k127_1396364_2 Rubrerythrin - - - 0.00000000000000000000000000000001101 132.0
DTH2_k127_1455733_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 391.0
DTH2_k127_1455733_1 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 309.0
DTH2_k127_1455733_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 291.0
DTH2_k127_1455733_3 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004642 275.0
DTH2_k127_1455733_4 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003927 271.0
DTH2_k127_1455733_5 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000001264 250.0
DTH2_k127_1455733_6 PFAM regulatory protein, LysR - - - 0.00000000000000000000000000000000000000000000001362 184.0
DTH2_k127_1455733_7 - - - - 0.000000007483 64.0
DTH2_k127_1494808_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.892e-269 833.0
DTH2_k127_1494808_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.308e-260 807.0
DTH2_k127_1494808_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 362.0
DTH2_k127_1494808_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 338.0
DTH2_k127_1494808_4 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 251.0
DTH2_k127_1494808_5 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000009273 184.0
DTH2_k127_1494808_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000003017 175.0
DTH2_k127_1494808_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000008448 160.0
DTH2_k127_1494808_8 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000000004422 143.0
DTH2_k127_1504924_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 534.0
DTH2_k127_1504924_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004902 265.0
DTH2_k127_1504924_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 2.5.1.120,2.5.1.77 0.00000000000000000000001842 101.0
DTH2_k127_1504924_3 Domain of unknown function (DUF4384) - - - 0.0001531 49.0
DTH2_k127_1506502_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 554.0
DTH2_k127_1506502_1 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000004236 180.0
DTH2_k127_1506502_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000009191 157.0
DTH2_k127_1506502_3 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000001741 105.0
DTH2_k127_1506502_4 Hsp20/alpha crystallin family K13993 - - 0.000000002574 58.0
DTH2_k127_1530641_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 6.116e-287 906.0
DTH2_k127_1530641_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 543.0
DTH2_k127_1530641_10 Glycosyl transferase group 1 K00696,K13058 GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000004171 265.0
DTH2_k127_1530641_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000002781 230.0
DTH2_k127_1530641_12 Transcriptional - - - 0.000000000000000000000000000000000172 135.0
DTH2_k127_1530641_13 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000005087 143.0
DTH2_k127_1530641_14 protein domain associated with - - - 0.00000000000000000000000000004269 122.0
DTH2_k127_1530641_16 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000006685 107.0
DTH2_k127_1530641_18 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000305 77.0
DTH2_k127_1530641_19 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000003178 79.0
DTH2_k127_1530641_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 508.0
DTH2_k127_1530641_20 - - - - 0.00000000003117 66.0
DTH2_k127_1530641_3 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 501.0
DTH2_k127_1530641_4 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 462.0
DTH2_k127_1530641_5 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 446.0
DTH2_k127_1530641_6 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 385.0
DTH2_k127_1530641_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 371.0
DTH2_k127_1530641_8 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 292.0
DTH2_k127_1530641_9 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001256 264.0
DTH2_k127_1572186_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 514.0
DTH2_k127_1572186_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 507.0
DTH2_k127_1572186_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 367.0
DTH2_k127_1572186_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 342.0
DTH2_k127_1572186_4 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 338.0
DTH2_k127_1572186_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001828 284.0
DTH2_k127_1572186_6 NosL - - - 0.0000000000000000000000000000000000000000000000000000000000001178 215.0
DTH2_k127_1572186_7 NosL - - - 0.0000000000000000000000000000000000000000000000000008347 188.0
DTH2_k127_1572186_8 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000000001018 137.0
DTH2_k127_1572186_9 - - - - 0.00000000000000000000000000001359 121.0
DTH2_k127_1680046_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.063e-263 819.0
DTH2_k127_1680046_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 336.0
DTH2_k127_1680046_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000006013 223.0
DTH2_k127_1689608_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 582.0
DTH2_k127_1689608_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 542.0
DTH2_k127_1689608_10 ORF6N domain - - - 0.00025 45.0
DTH2_k127_1689608_11 TIGRFAM CRISPR-associated helicase Cas3 K07012 - - 0.0005734 46.0
DTH2_k127_1689608_2 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 467.0
DTH2_k127_1689608_3 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
DTH2_k127_1689608_4 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 288.0
DTH2_k127_1689608_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000006991 239.0
DTH2_k127_1689608_6 PIN domain - - - 0.00000000000000000008822 94.0
DTH2_k127_1689608_7 Protein of unknown function (DUF456) K09793 - - 0.00000000000000002447 83.0
DTH2_k127_1689608_9 integrase domain protein SAM domain protein K03733,K04763 GO:0008150,GO:0040007 - 0.0001228 47.0
DTH2_k127_1697930_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.074e-194 624.0
DTH2_k127_1697930_1 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 385.0
DTH2_k127_1697930_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 342.0
DTH2_k127_1697930_3 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 342.0
DTH2_k127_1697930_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004232 277.0
DTH2_k127_1697930_5 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000000006316 195.0
DTH2_k127_1697930_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000009954 62.0
DTH2_k127_1719527_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.889e-262 820.0
DTH2_k127_1719527_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 6.706e-252 792.0
DTH2_k127_1719527_10 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567,K10778 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000001235 136.0
DTH2_k127_1719527_11 - - - - 0.00000001308 68.0
DTH2_k127_1719527_12 - - - - 0.00003759 52.0
DTH2_k127_1719527_2 PFAM Glycosyl transferase family 2 K20444 - - 1.511e-248 816.0
DTH2_k127_1719527_3 Methyltransferase type 11 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 439.0
DTH2_k127_1719527_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 308.0
DTH2_k127_1719527_5 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006073 279.0
DTH2_k127_1719527_6 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
DTH2_k127_1719527_7 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000001201 224.0
DTH2_k127_1719527_8 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000002526 227.0
DTH2_k127_1719527_9 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000001899 188.0
DTH2_k127_1723137_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 453.0
DTH2_k127_1723137_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 387.0
DTH2_k127_1723137_2 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 311.0
DTH2_k127_1723137_3 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000006683 154.0
DTH2_k127_1723137_4 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000001616 113.0
DTH2_k127_1723137_5 - - - - 0.000000000001993 68.0
DTH2_k127_1786093_0 PFAM Transketolase K00615 - 2.2.1.1 3.699e-257 805.0
DTH2_k127_1786093_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 491.0
DTH2_k127_1786093_10 Phage integrase, N-terminal SAM-like domain - - - 0.00000000255 61.0
DTH2_k127_1786093_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 372.0
DTH2_k127_1786093_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 368.0
DTH2_k127_1786093_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 374.0
DTH2_k127_1786093_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003206 248.0
DTH2_k127_1786093_6 - - - - 0.00000000000000000000000000000000000000000000000000000006659 202.0
DTH2_k127_1786093_7 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000001147 161.0
DTH2_k127_1786093_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000296 137.0
DTH2_k127_1786093_9 Signal transduction histidine kinase - - - 0.0000000005399 66.0
DTH2_k127_1809005_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.077e-205 656.0
DTH2_k127_1809005_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 553.0
DTH2_k127_1809005_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 385.0
DTH2_k127_1809005_11 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 386.0
DTH2_k127_1809005_12 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 372.0
DTH2_k127_1809005_13 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 354.0
DTH2_k127_1809005_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 349.0
DTH2_k127_1809005_15 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 353.0
DTH2_k127_1809005_16 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 314.0
DTH2_k127_1809005_17 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 293.0
DTH2_k127_1809005_18 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001157 284.0
DTH2_k127_1809005_19 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 255.0
DTH2_k127_1809005_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 528.0
DTH2_k127_1809005_20 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000002481 218.0
DTH2_k127_1809005_21 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000005732 209.0
DTH2_k127_1809005_22 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000000002861 203.0
DTH2_k127_1809005_23 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000000205 174.0
DTH2_k127_1809005_24 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000007172 112.0
DTH2_k127_1809005_25 aminopeptidase N - - - 0.0000000000000005324 83.0
DTH2_k127_1809005_28 Regulatory protein, FmdB family - - - 0.00000004477 57.0
DTH2_k127_1809005_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 470.0
DTH2_k127_1809005_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 458.0
DTH2_k127_1809005_5 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 459.0
DTH2_k127_1809005_6 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 434.0
DTH2_k127_1809005_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 417.0
DTH2_k127_1809005_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 397.0
DTH2_k127_1809005_9 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 387.0
DTH2_k127_1809097_0 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 486.0
DTH2_k127_1809097_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 456.0
DTH2_k127_1809097_10 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 335.0
DTH2_k127_1809097_11 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 314.0
DTH2_k127_1809097_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002526 259.0
DTH2_k127_1809097_13 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004541 253.0
DTH2_k127_1809097_14 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000001423 246.0
DTH2_k127_1809097_15 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000003869 226.0
DTH2_k127_1809097_16 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000001166 191.0
DTH2_k127_1809097_17 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000007775 184.0
DTH2_k127_1809097_18 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000004454 166.0
DTH2_k127_1809097_19 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000944 167.0
DTH2_k127_1809097_2 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 445.0
DTH2_k127_1809097_20 SMART Cold shock protein K03704 - - 0.000000000000000000000000003203 111.0
DTH2_k127_1809097_21 rubredoxin - - - 0.00000000000000000000000173 102.0
DTH2_k127_1809097_22 - - - - 0.00000000000000000000007712 106.0
DTH2_k127_1809097_25 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000009729 57.0
DTH2_k127_1809097_26 Aspartyl protease K06985 - - 0.0009007 49.0
DTH2_k127_1809097_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 439.0
DTH2_k127_1809097_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 422.0
DTH2_k127_1809097_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 421.0
DTH2_k127_1809097_6 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 417.0
DTH2_k127_1809097_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 411.0
DTH2_k127_1809097_8 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 346.0
DTH2_k127_1809097_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 346.0
DTH2_k127_1830759_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.463e-266 842.0
DTH2_k127_1830759_1 Ftsk_gamma K03466 - - 2.691e-209 677.0
DTH2_k127_1830759_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.105e-198 633.0
DTH2_k127_1830759_3 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 497.0
DTH2_k127_1830759_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 395.0
DTH2_k127_1830759_5 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 373.0
DTH2_k127_1830759_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002056 267.0
DTH2_k127_1830759_7 NOG31153 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 244.0
DTH2_k127_1830759_8 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000002271 205.0
DTH2_k127_1830759_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000001128 78.0
DTH2_k127_1831573_0 FAD binding domain K00394 - 1.8.99.2 0.0 1127.0
DTH2_k127_1831573_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 609.0
DTH2_k127_1831573_2 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001788 248.0
DTH2_k127_1856973_0 FtsX-like permease family K02004 - - 1.968e-303 948.0
DTH2_k127_1856973_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 1.063e-237 749.0
DTH2_k127_1856973_10 - - - - 0.00000000000000000645 92.0
DTH2_k127_1856973_11 ATP adenylyltransferase K00988 - 2.7.7.53 0.0008175 45.0
DTH2_k127_1856973_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 547.0
DTH2_k127_1856973_3 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 392.0
DTH2_k127_1856973_4 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 377.0
DTH2_k127_1856973_5 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 349.0
DTH2_k127_1856973_6 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 336.0
DTH2_k127_1856973_7 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000846 252.0
DTH2_k127_1856973_8 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000139 203.0
DTH2_k127_1856973_9 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000001485 217.0
DTH2_k127_1904890_0 DNA photolyase K01669 - 4.1.99.3 7.679e-198 625.0
DTH2_k127_1904890_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 528.0
DTH2_k127_1904890_3 - - - - 0.0008796 48.0
DTH2_k127_2103949_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 417.0
DTH2_k127_2103949_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 394.0
DTH2_k127_2103949_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
DTH2_k127_2103949_3 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000004375 228.0
DTH2_k127_2103949_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000006913 231.0
DTH2_k127_2103949_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000001083 198.0
DTH2_k127_2103949_6 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000004554 147.0
DTH2_k127_2103949_7 Cell surface protein - - - 0.000000000000007457 85.0
DTH2_k127_2123506_0 Type II/IV secretion system protein K02454,K02652 - - 9.3e-204 650.0
DTH2_k127_2123506_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 463.0
DTH2_k127_2123506_2 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 406.0
DTH2_k127_2123506_3 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 320.0
DTH2_k127_2123506_4 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000003074 146.0
DTH2_k127_2123506_5 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000003198 125.0
DTH2_k127_2123506_6 Pilus assembly protein, PilP K02665 - - 0.0000000000003614 77.0
DTH2_k127_2123506_7 response regulator receiver K02487,K06596 - - 0.0000001593 55.0
DTH2_k127_2123506_8 Bacterial Ig-like domain (group 1) - - - 0.0001742 51.0
DTH2_k127_2156953_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.78e-208 654.0
DTH2_k127_2156953_1 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 572.0
DTH2_k127_2156953_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000007686 155.0
DTH2_k127_2184289_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.862e-266 855.0
DTH2_k127_2184289_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.203e-260 807.0
DTH2_k127_2184289_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 316.0
DTH2_k127_2184289_11 PFAM Glycosyl transferase family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 317.0
DTH2_k127_2184289_12 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003344 268.0
DTH2_k127_2184289_13 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
DTH2_k127_2184289_14 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000004248 235.0
DTH2_k127_2184289_15 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000006709 207.0
DTH2_k127_2184289_16 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000003604 194.0
DTH2_k127_2184289_17 crp fnr family K01420 - - 0.000000000000000000000000000000000000000000002597 172.0
DTH2_k127_2184289_18 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000005871 126.0
DTH2_k127_2184289_19 Tetratricopeptide repeat - - - 0.00000000000000000000003888 108.0
DTH2_k127_2184289_2 Highly conserved protein containing a thioredoxin domain K06888 - - 4.995e-246 775.0
DTH2_k127_2184289_20 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000009177 97.0
DTH2_k127_2184289_22 - - - - 0.00003024 47.0
DTH2_k127_2184289_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 509.0
DTH2_k127_2184289_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 476.0
DTH2_k127_2184289_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 430.0
DTH2_k127_2184289_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 403.0
DTH2_k127_2184289_7 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 379.0
DTH2_k127_2184289_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 387.0
DTH2_k127_2184289_9 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 368.0
DTH2_k127_2200505_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.04e-321 1000.0
DTH2_k127_2200505_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 585.0
DTH2_k127_2200505_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000002096 220.0
DTH2_k127_2200505_11 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000001576 213.0
DTH2_k127_2200505_12 shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000007832 194.0
DTH2_k127_2200505_13 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000071 147.0
DTH2_k127_2200505_14 RDD family - - - 0.000000000000000000000000000002722 124.0
DTH2_k127_2200505_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 522.0
DTH2_k127_2200505_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 508.0
DTH2_k127_2200505_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 450.0
DTH2_k127_2200505_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 447.0
DTH2_k127_2200505_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 382.0
DTH2_k127_2200505_7 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 299.0
DTH2_k127_2200505_8 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 289.0
DTH2_k127_2200505_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000003446 240.0
DTH2_k127_2279926_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 495.0
DTH2_k127_2279926_1 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000007749 195.0
DTH2_k127_2279926_2 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000002237 186.0
DTH2_k127_2279926_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000024 168.0
DTH2_k127_2279926_4 Uncharacterized protein family UPF0054 K07042 - - 0.000000000000000000000002603 109.0
DTH2_k127_2279926_5 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000003168 106.0
DTH2_k127_2279926_6 PFAM PIN domain - - - 0.0000001925 59.0
DTH2_k127_2449587_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.197e-303 950.0
DTH2_k127_2449587_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.653e-242 759.0
DTH2_k127_2449587_10 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000001068 158.0
DTH2_k127_2449587_11 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.00000000000000000000000000000001835 128.0
DTH2_k127_2449587_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03427 - 2.1.1.72 0.000000000000000000000000000833 113.0
DTH2_k127_2449587_14 - - - - 0.00000001708 61.0
DTH2_k127_2449587_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 1.626e-240 756.0
DTH2_k127_2449587_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 565.0
DTH2_k127_2449587_4 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 519.0
DTH2_k127_2449587_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 397.0
DTH2_k127_2449587_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 357.0
DTH2_k127_2449587_7 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 327.0
DTH2_k127_2449587_8 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 307.0
DTH2_k127_2449587_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000001634 244.0
DTH2_k127_2543381_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 5.335e-215 674.0
DTH2_k127_2543381_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 507.0
DTH2_k127_2543381_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 491.0
DTH2_k127_2543381_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 385.0
DTH2_k127_2543381_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 333.0
DTH2_k127_2543381_5 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003246 253.0
DTH2_k127_2644904_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1259.0
DTH2_k127_2644904_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 505.0
DTH2_k127_2644904_10 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002413 282.0
DTH2_k127_2644904_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 272.0
DTH2_k127_2644904_12 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005689 277.0
DTH2_k127_2644904_13 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000005687 246.0
DTH2_k127_2644904_14 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008351 244.0
DTH2_k127_2644904_15 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001798 211.0
DTH2_k127_2644904_16 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000001152 208.0
DTH2_k127_2644904_17 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000002272 192.0
DTH2_k127_2644904_18 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000005032 179.0
DTH2_k127_2644904_19 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000003396 171.0
DTH2_k127_2644904_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 487.0
DTH2_k127_2644904_20 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000001229 143.0
DTH2_k127_2644904_21 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000142 130.0
DTH2_k127_2644904_22 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000008908 119.0
DTH2_k127_2644904_23 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000001995 111.0
DTH2_k127_2644904_24 Protein of unknown function (DUF2905) - - - 0.000000000000000000005437 95.0
DTH2_k127_2644904_25 Sporulation related domain - - - 0.000284 51.0
DTH2_k127_2644904_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 473.0
DTH2_k127_2644904_4 restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 378.0
DTH2_k127_2644904_5 Transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 340.0
DTH2_k127_2644904_6 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 333.0
DTH2_k127_2644904_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 330.0
DTH2_k127_2644904_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 323.0
DTH2_k127_2644904_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003127 280.0
DTH2_k127_2649208_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000006779 222.0
DTH2_k127_2649208_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000005039 133.0
DTH2_k127_2649208_2 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000002785 100.0
DTH2_k127_2649208_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000003474 92.0
DTH2_k127_2657061_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 562.0
DTH2_k127_2657061_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 489.0
DTH2_k127_2657061_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 416.0
DTH2_k127_2657061_3 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 378.0
DTH2_k127_2657061_4 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 323.0
DTH2_k127_2657061_5 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000004073 151.0
DTH2_k127_2657061_6 - - - - 0.000000000000000000000826 102.0
DTH2_k127_2657061_8 phosphorelay signal transduction system K02481 - - 0.000005492 49.0
DTH2_k127_2669578_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 600.0
DTH2_k127_2669578_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 535.0
DTH2_k127_2669578_10 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000006041 187.0
DTH2_k127_2669578_11 metal cluster binding K06940,K18475 - - 0.000000000000000000000000000000000004107 150.0
DTH2_k127_2669578_12 Cytochrome c - - - 0.000000000000000000000000000005248 126.0
DTH2_k127_2669578_2 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 417.0
DTH2_k127_2669578_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 364.0
DTH2_k127_2669578_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 319.0
DTH2_k127_2669578_5 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 302.0
DTH2_k127_2669578_6 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002007 254.0
DTH2_k127_2669578_7 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000005045 239.0
DTH2_k127_2669578_8 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000002235 214.0
DTH2_k127_2669578_9 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000008929 217.0
DTH2_k127_2679891_0 Domain of unknown function DUF11 - - - 0.0 1307.0
DTH2_k127_2679891_1 FAD binding domain K00278 - 1.4.3.16 1.525e-201 640.0
DTH2_k127_2679891_10 NifU-like N terminal domain K04488,K07126,K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 354.0
DTH2_k127_2679891_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 360.0
DTH2_k127_2679891_12 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 308.0
DTH2_k127_2679891_13 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
DTH2_k127_2679891_14 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 299.0
DTH2_k127_2679891_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 289.0
DTH2_k127_2679891_16 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004419 274.0
DTH2_k127_2679891_17 Cytochrome b/b6/petB K03887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001319 273.0
DTH2_k127_2679891_18 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001316 265.0
DTH2_k127_2679891_19 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000663 261.0
DTH2_k127_2679891_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 579.0
DTH2_k127_2679891_20 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000001449 254.0
DTH2_k127_2679891_21 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000004373 250.0
DTH2_k127_2679891_22 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000008203 243.0
DTH2_k127_2679891_23 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
DTH2_k127_2679891_24 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000000002116 162.0
DTH2_k127_2679891_25 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000268 159.0
DTH2_k127_2679891_26 Belongs to the ompA family - - - 0.000000000000000000000000000007032 141.0
DTH2_k127_2679891_27 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000138 112.0
DTH2_k127_2679891_28 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000002175 118.0
DTH2_k127_2679891_29 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000003399 110.0
DTH2_k127_2679891_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 534.0
DTH2_k127_2679891_30 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000001813 112.0
DTH2_k127_2679891_31 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000006005 111.0
DTH2_k127_2679891_32 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000000000000000000000007144 124.0
DTH2_k127_2679891_34 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000006788 81.0
DTH2_k127_2679891_35 PFAM regulatory protein AsnC Lrp family - - - 0.00000002662 59.0
DTH2_k127_2679891_36 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000007921 57.0
DTH2_k127_2679891_4 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 525.0
DTH2_k127_2679891_5 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 504.0
DTH2_k127_2679891_6 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 494.0
DTH2_k127_2679891_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 472.0
DTH2_k127_2679891_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 455.0
DTH2_k127_2679891_9 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 426.0
DTH2_k127_2692506_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 443.0
DTH2_k127_2692506_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 349.0
DTH2_k127_2692506_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 355.0
DTH2_k127_2692506_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 362.0
DTH2_k127_2692506_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 325.0
DTH2_k127_2703198_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 6.111e-304 939.0
DTH2_k127_2703198_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 7.554e-288 901.0
DTH2_k127_2703198_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000001444 224.0
DTH2_k127_2703198_12 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000001901 213.0
DTH2_k127_2703198_13 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000002016 170.0
DTH2_k127_2703198_14 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000001373 148.0
DTH2_k127_2703198_15 AMP binding - - - 0.0000000000000000000000000000008916 126.0
DTH2_k127_2703198_16 COGs COG4446 conserved - - - 0.0000000000000000000000000002499 118.0
DTH2_k127_2703198_18 protein secretion K03116,K03117 - - 0.000000000000007521 79.0
DTH2_k127_2703198_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 483.0
DTH2_k127_2703198_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 467.0
DTH2_k127_2703198_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 419.0
DTH2_k127_2703198_5 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 359.0
DTH2_k127_2703198_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 332.0
DTH2_k127_2703198_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 334.0
DTH2_k127_2703198_8 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001875 288.0
DTH2_k127_2703198_9 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004946 266.0
DTH2_k127_2722690_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1102.0
DTH2_k127_2722690_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 526.0
DTH2_k127_2722690_11 HDOD domain - - - 0.00000000000000000000376 106.0
DTH2_k127_2722690_12 Histidine kinase - - - 0.00000142 60.0
DTH2_k127_2722690_2 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 291.0
DTH2_k127_2722690_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 276.0
DTH2_k127_2722690_4 4Fe-4S binding domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007015 275.0
DTH2_k127_2722690_5 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
DTH2_k127_2722690_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000002728 214.0
DTH2_k127_2722690_7 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000008069 201.0
DTH2_k127_2722690_8 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000005255 199.0
DTH2_k127_2722690_9 PFAM ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000005171 192.0
DTH2_k127_2724482_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 505.0
DTH2_k127_2724482_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 436.0
DTH2_k127_2724482_2 eight transmembrane protein EpsH - - - 0.00000000000000000000000000000000000000008826 163.0
DTH2_k127_2724482_3 VanZ like family - - - 0.00000000000004433 77.0
DTH2_k127_2724482_4 calcium ion binding K02599,K06052,K10737 - 3.6.4.12 0.0003949 52.0
DTH2_k127_2726472_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.04e-226 720.0
DTH2_k127_2726472_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001622 262.0
DTH2_k127_2726472_2 EamA-like transporter family - - - 0.000000007071 57.0
DTH2_k127_2726472_4 Protein of unknown function (DUF1573) - - - 0.000001691 51.0
DTH2_k127_2726472_5 - - - - 0.0003129 47.0
DTH2_k127_2726472_6 Protein of unknown function (DUF2934) - - - 0.0003196 46.0
DTH2_k127_2775886_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.094e-235 751.0
DTH2_k127_2775886_1 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 5.903e-208 660.0
DTH2_k127_2775886_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 357.0
DTH2_k127_2775886_11 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001275 272.0
DTH2_k127_2775886_12 - - - - 0.00000000000000000000000000000000000000000000000000000000353 208.0
DTH2_k127_2775886_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000005877 207.0
DTH2_k127_2775886_14 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000023 145.0
DTH2_k127_2775886_15 Pyrophosphatase - - - 0.00000000000000000000000000000000007299 136.0
DTH2_k127_2775886_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000004099 107.0
DTH2_k127_2775886_17 gas vesicle protein - - - 0.00000000000000000000288 97.0
DTH2_k127_2775886_18 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000004769 92.0
DTH2_k127_2775886_19 thiamine diphosphate biosynthetic process K03154 - - 0.000000000005396 69.0
DTH2_k127_2775886_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 614.0
DTH2_k127_2775886_20 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000002033 62.0
DTH2_k127_2775886_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 580.0
DTH2_k127_2775886_4 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 483.0
DTH2_k127_2775886_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 471.0
DTH2_k127_2775886_6 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 465.0
DTH2_k127_2775886_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 448.0
DTH2_k127_2775886_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 439.0
DTH2_k127_2775886_9 methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 423.0
DTH2_k127_2815953_0 pfam abc K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 321.0
DTH2_k127_2815953_1 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
DTH2_k127_2815953_2 Peptidylprolyl isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001393 203.0
DTH2_k127_2815953_3 Transport permease protein K09690 - - 0.0000000000000000000000000000000000000000000005093 176.0
DTH2_k127_2815953_4 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000000000006282 140.0
DTH2_k127_2815953_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000001574 132.0
DTH2_k127_2815953_6 transferase activity, transferring acyl groups - - - 0.000000000000000000000002738 118.0
DTH2_k127_2827239_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 358.0
DTH2_k127_2827239_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 315.0
DTH2_k127_2827239_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
DTH2_k127_2827239_3 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000003604 220.0
DTH2_k127_2827239_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000005316 193.0
DTH2_k127_2827239_5 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000001188 72.0
DTH2_k127_2832762_0 Glycosyl hydrolase family 57 - - - 6.144e-249 775.0
DTH2_k127_2832762_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 391.0
DTH2_k127_2832762_11 - - - - 0.0009014 46.0
DTH2_k127_2832762_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 342.0
DTH2_k127_2832762_3 Ferritin Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 299.0
DTH2_k127_2832762_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002129 277.0
DTH2_k127_2832762_5 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000003077 210.0
DTH2_k127_2832762_6 HDOD domain - - - 0.000000000000000000000000000000000000000000000000001717 193.0
DTH2_k127_2832762_7 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000003972 148.0
DTH2_k127_2832762_8 Haemolytic - - - 0.0000000000000000000004739 102.0
DTH2_k127_2832762_9 Protein of unknown function (DUF3187) - - - 0.0000000000000000000009095 106.0
DTH2_k127_2884883_0 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 437.0
DTH2_k127_2884883_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 312.0
DTH2_k127_2884883_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000001592 178.0
DTH2_k127_2884883_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000001295 78.0
DTH2_k127_2902791_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1070.0
DTH2_k127_2902791_1 LysM domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 342.0
DTH2_k127_2902791_2 2Fe-2S -binding domain K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000001209 237.0
DTH2_k127_2902791_3 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000003731 145.0
DTH2_k127_2902791_5 - - - - 0.00003569 48.0
DTH2_k127_290604_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 535.0
DTH2_k127_290604_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 468.0
DTH2_k127_290604_10 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000258 228.0
DTH2_k127_290604_11 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000001294 216.0
DTH2_k127_290604_12 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000000001627 205.0
DTH2_k127_290604_13 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.00000000000000000000000000000000000000000000000000000005162 207.0
DTH2_k127_290604_14 UPF0056 membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000006773 184.0
DTH2_k127_290604_15 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000001074 177.0
DTH2_k127_290604_16 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000216 176.0
DTH2_k127_290604_17 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000002898 166.0
DTH2_k127_290604_18 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000001449 153.0
DTH2_k127_290604_2 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 452.0
DTH2_k127_290604_20 YGGT family K02221 - - 0.0000000000000000000000000000001887 128.0
DTH2_k127_290604_21 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000007749 97.0
DTH2_k127_290604_22 Regulatory protein, FmdB family - - - 0.00000000000000000005144 93.0
DTH2_k127_290604_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 404.0
DTH2_k127_290604_4 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 381.0
DTH2_k127_290604_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 343.0
DTH2_k127_290604_6 CobB/CobQ-like glutamine amidotransferase domain K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 340.0
DTH2_k127_290604_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 291.0
DTH2_k127_290604_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000256 268.0
DTH2_k127_290604_9 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000007274 261.0
DTH2_k127_2912260_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 524.0
DTH2_k127_2912260_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 327.0
DTH2_k127_2912260_2 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001435 276.0
DTH2_k127_2912260_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000004348 165.0
DTH2_k127_2912260_4 PFAM FlhB HrpN YscU SpaS Family K04061 - - 0.000000000000000000000006686 103.0
DTH2_k127_2912260_5 Belongs to the bacterial flagellin family K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000145 103.0
DTH2_k127_2912260_8 PFAM Anti-sigma-28 factor FlgM family protein K02398 - - 0.000001007 54.0
DTH2_k127_2976786_0 Elongation factor SelB, winged helix K03833 - - 1.363e-218 697.0
DTH2_k127_2976786_1 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 3.288e-208 677.0
DTH2_k127_2976786_10 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000001926 132.0
DTH2_k127_2976786_11 Protein of unknown function (DUF1648) - - - 0.000000000000000000002851 102.0
DTH2_k127_2976786_12 - - - - 0.000000144 57.0
DTH2_k127_2976786_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 547.0
DTH2_k127_2976786_3 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 323.0
DTH2_k127_2976786_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000007612 257.0
DTH2_k127_2976786_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000002894 239.0
DTH2_k127_2976786_6 sulfur carrier activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001834 232.0
DTH2_k127_2976786_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000004417 196.0
DTH2_k127_2976786_8 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000003438 193.0
DTH2_k127_2976786_9 PFAM PHP domain - - - 0.00000000000000000000000000000000001375 143.0
DTH2_k127_298070_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5e-324 1003.0
DTH2_k127_298070_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 3.922e-275 856.0
DTH2_k127_298070_2 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 385.0
DTH2_k127_298070_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
DTH2_k127_298070_4 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000008339 149.0
DTH2_k127_298070_5 Ion channel - - - 0.000000000000000000000000000000004163 137.0
DTH2_k127_298070_6 PIN domain - - - 0.00002301 53.0
DTH2_k127_3151489_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 490.0
DTH2_k127_3151489_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 426.0
DTH2_k127_3151489_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 286.0
DTH2_k127_3151489_3 PINc domain ribonuclease K09006 - - 0.0000000000000000000000000000000000000000000000000000000000000002236 231.0
DTH2_k127_3151489_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000001148 174.0
DTH2_k127_3151489_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000001114 128.0
DTH2_k127_3151489_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000008882 124.0
DTH2_k127_3151489_7 TPR repeat - - - 0.0000000000000000000000001574 111.0
DTH2_k127_3181578_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 578.0
DTH2_k127_3181578_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002064 264.0
DTH2_k127_3181578_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000003712 205.0
DTH2_k127_3181578_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000002616 151.0
DTH2_k127_3181578_4 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000663 156.0
DTH2_k127_3181578_5 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000001628 145.0
DTH2_k127_3181578_6 SMART Cold shock protein K03704 - - 0.0000000000000000000000000001052 115.0
DTH2_k127_3181578_7 - - - - 0.0000000000000000005972 88.0
DTH2_k127_3181578_8 - - - - 0.000000000002279 72.0
DTH2_k127_3264356_0 Domain of unknown function (DUF3413) K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 344.0
DTH2_k127_3264356_1 PFAM glycosyl transferase, family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 316.0
DTH2_k127_3264356_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001526 241.0
DTH2_k127_3264356_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000002163 190.0
DTH2_k127_3264356_4 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000000000000000000000000000001213 167.0
DTH2_k127_3291687_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0 1130.0
DTH2_k127_3291687_1 cell redox homeostasis - - - 6.735e-223 700.0
DTH2_k127_3291687_10 Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001731 287.0
DTH2_k127_3291687_11 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000149 224.0
DTH2_k127_3291687_12 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000001461 196.0
DTH2_k127_3291687_13 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000007211 184.0
DTH2_k127_3291687_14 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000004939 160.0
DTH2_k127_3291687_15 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000002471 153.0
DTH2_k127_3291687_2 Aminotransferase class-III K01845 - 5.4.3.8 8.969e-209 657.0
DTH2_k127_3291687_3 Polysulphide reductase, NrfD - - - 2.89e-202 636.0
DTH2_k127_3291687_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 423.0
DTH2_k127_3291687_5 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 386.0
DTH2_k127_3291687_6 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 342.0
DTH2_k127_3291687_7 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 328.0
DTH2_k127_3291687_8 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 309.0
DTH2_k127_3291687_9 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 289.0
DTH2_k127_3367360_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1723.0
DTH2_k127_3367360_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 370.0
DTH2_k127_3367360_2 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000003776 219.0
DTH2_k127_3367360_3 nucleotide metabolic process - - - 0.00000000000000000000000000000000001415 144.0
DTH2_k127_3367360_4 Zinc-dependent metalloprotease - - - 0.000000000001181 74.0
DTH2_k127_3422968_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 557.0
DTH2_k127_3422968_1 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002331 276.0
DTH2_k127_3422968_10 Type IV pilus assembly protein PilM; K02461 - - 0.000004477 59.0
DTH2_k127_3422968_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000004841 205.0
DTH2_k127_3422968_3 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000008339 149.0
DTH2_k127_3422968_4 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000005922 122.0
DTH2_k127_3422968_5 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000003952 113.0
DTH2_k127_3422968_6 - - - - 0.000000000001789 80.0
DTH2_k127_3422968_7 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000001601 61.0
DTH2_k127_3422968_9 General secretion pathway protein H K02457 - - 0.000000188 61.0
DTH2_k127_3523041_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1161.0
DTH2_k127_3523041_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000002217 150.0
DTH2_k127_3523041_2 AMP binding - - - 0.000000000000000000000000452 109.0
DTH2_k127_366770_0 PD-(D/E)XK nuclease superfamily - - - 2.249e-216 707.0
DTH2_k127_366770_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 2.126e-213 670.0
DTH2_k127_366770_10 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 294.0
DTH2_k127_366770_11 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
DTH2_k127_366770_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005386 267.0
DTH2_k127_366770_13 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000008557 217.0
DTH2_k127_366770_14 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000001355 176.0
DTH2_k127_366770_15 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000001009 168.0
DTH2_k127_366770_16 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000005833 145.0
DTH2_k127_366770_17 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000001046 92.0
DTH2_k127_366770_2 Belongs to the helicase family. UvrD subfamily - - - 4.611e-207 677.0
DTH2_k127_366770_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.244e-199 626.0
DTH2_k127_366770_4 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 498.0
DTH2_k127_366770_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 430.0
DTH2_k127_366770_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 417.0
DTH2_k127_366770_7 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 388.0
DTH2_k127_366770_8 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 339.0
DTH2_k127_366770_9 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 332.0
DTH2_k127_372426_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 503.0
DTH2_k127_372426_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 319.0
DTH2_k127_372426_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004702 270.0
DTH2_k127_372426_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000237 194.0
DTH2_k127_372426_4 OstA-like protein K09774 - - 0.0000000000000000000000000000000000000000000000001201 182.0
DTH2_k127_372426_5 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000001654 106.0
DTH2_k127_3809608_0 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 507.0
DTH2_k127_3809608_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 491.0
DTH2_k127_3809608_10 HicB family - - - 0.0000000000000000000000000000000000000006128 151.0
DTH2_k127_3809608_11 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000000000014 136.0
DTH2_k127_3809608_12 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.00002812 46.0
DTH2_k127_3809608_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 466.0
DTH2_k127_3809608_3 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 467.0
DTH2_k127_3809608_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 445.0
DTH2_k127_3809608_5 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 440.0
DTH2_k127_3809608_6 Putative regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003259 229.0
DTH2_k127_3809608_7 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000000002113 203.0
DTH2_k127_3809608_8 - - - - 0.00000000000000000000000000000000000000000000002617 172.0
DTH2_k127_3809608_9 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.00000000000000000000000000000000000000000009265 163.0
DTH2_k127_3826494_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1e-323 1014.0
DTH2_k127_3826494_1 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 578.0
DTH2_k127_3826494_10 - - - - 0.00000000000738 72.0
DTH2_k127_3826494_11 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00001129 53.0
DTH2_k127_3826494_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 534.0
DTH2_k127_3826494_3 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000001977 237.0
DTH2_k127_3826494_4 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000085 208.0
DTH2_k127_3826494_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000001591 194.0
DTH2_k127_3826494_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000003443 158.0
DTH2_k127_3826494_7 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000001586 130.0
DTH2_k127_3826494_8 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000000001342 118.0
DTH2_k127_3826494_9 PFAM Rhodanese domain protein - - - 0.00000000000000000008763 90.0
DTH2_k127_3861557_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 362.0
DTH2_k127_3861557_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 342.0
DTH2_k127_3861557_2 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002685 268.0
DTH2_k127_3861557_3 denitrification pathway - - - 0.0000000003921 63.0
DTH2_k127_3861557_4 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000002397 56.0
DTH2_k127_3884075_0 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 606.0
DTH2_k127_3884075_1 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 398.0
DTH2_k127_3884075_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 368.0
DTH2_k127_3884075_3 Protein-tyrosine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 313.0
DTH2_k127_3884075_4 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000273 164.0
DTH2_k127_39020_0 Telomere recombination K04656 - - 1.446e-218 698.0
DTH2_k127_39020_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.377e-200 636.0
DTH2_k127_39020_10 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000004349 115.0
DTH2_k127_39020_11 Diacylglycerol kinase catalytic domain K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.000000000208 68.0
DTH2_k127_39020_12 Domain of unknown function (DUF1992) - - - 0.0000001389 53.0
DTH2_k127_39020_2 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 346.0
DTH2_k127_39020_3 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 308.0
DTH2_k127_39020_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
DTH2_k127_39020_5 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000003301 206.0
DTH2_k127_39020_6 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000000004208 185.0
DTH2_k127_39020_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000966 159.0
DTH2_k127_39020_8 cell redox homeostasis K02199 - - 0.00000000000000000000000000000004296 132.0
DTH2_k127_39020_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002388 112.0
DTH2_k127_3913599_0 Protein of unknown function (DUF3141) - - - 0.0 1034.0
DTH2_k127_3913599_1 alpha amylase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 548.0
DTH2_k127_3913599_2 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 548.0
DTH2_k127_3913599_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 327.0
DTH2_k127_3913599_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006193 242.0
DTH2_k127_3913599_5 YMGG-like Gly-zipper - - - 0.00000000000000000000000000000000000000000001535 167.0
DTH2_k127_3913599_6 - - - - 0.00000000000000000000000000001295 124.0
DTH2_k127_3913599_7 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000006871 88.0
DTH2_k127_3953406_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 597.0
DTH2_k127_3953406_1 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 584.0
DTH2_k127_3953406_10 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 346.0
DTH2_k127_3953406_11 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 342.0
DTH2_k127_3953406_12 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 340.0
DTH2_k127_3953406_13 Belongs to the MurCDEF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 319.0
DTH2_k127_3953406_14 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000003817 159.0
DTH2_k127_3953406_15 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000000000000234 158.0
DTH2_k127_3953406_16 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000004555 156.0
DTH2_k127_3953406_17 PFAM Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000002763 160.0
DTH2_k127_3953406_18 protein transport across the cell outer membrane K02452,K02463 - - 0.0000000000000000000000000000000005265 142.0
DTH2_k127_3953406_19 iron-sulfur cluster assembly - - - 0.00000000000000000000006465 103.0
DTH2_k127_3953406_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 593.0
DTH2_k127_3953406_20 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000001333 56.0
DTH2_k127_3953406_21 IMG reference gene - - - 0.000001866 52.0
DTH2_k127_3953406_22 - - - - 0.00001053 49.0
DTH2_k127_3953406_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 529.0
DTH2_k127_3953406_4 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 513.0
DTH2_k127_3953406_5 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 453.0
DTH2_k127_3953406_6 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 402.0
DTH2_k127_3953406_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 396.0
DTH2_k127_3953406_8 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 372.0
DTH2_k127_3953406_9 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 361.0
DTH2_k127_39699_0 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 518.0
DTH2_k127_39699_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 366.0
DTH2_k127_39699_2 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
DTH2_k127_39699_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 352.0
DTH2_k127_39699_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000001972 250.0
DTH2_k127_39699_5 MarR family transcriptional K15973 - - 0.000000000000000000000000000000000000000000000106 172.0
DTH2_k127_39699_6 Histidine kinase - - - 0.0000000000000000000000000000000002918 136.0
DTH2_k127_3972430_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 596.0
DTH2_k127_3972430_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 576.0
DTH2_k127_3972430_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000001816 200.0
DTH2_k127_3972430_11 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000007458 184.0
DTH2_k127_3972430_12 HNH nucleases - - - 0.000000000000000000000000000000000000000000001505 167.0
DTH2_k127_3972430_13 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000003025 154.0
DTH2_k127_3972430_14 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000001785 125.0
DTH2_k127_3972430_15 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000001568 115.0
DTH2_k127_3972430_16 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000004705 109.0
DTH2_k127_3972430_17 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000002167 68.0
DTH2_k127_3972430_2 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 550.0
DTH2_k127_3972430_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 425.0
DTH2_k127_3972430_4 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 352.0
DTH2_k127_3972430_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 325.0
DTH2_k127_3972430_6 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 290.0
DTH2_k127_3972430_7 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 288.0
DTH2_k127_3972430_8 Peptidase T-like protein K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003639 284.0
DTH2_k127_3972430_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000003194 232.0
DTH2_k127_3975227_0 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 543.0
DTH2_k127_3975227_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 531.0
DTH2_k127_3975227_10 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000001693 183.0
DTH2_k127_3975227_11 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000000005997 139.0
DTH2_k127_3975227_12 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001491 116.0
DTH2_k127_3975227_13 Tetratricopeptide repeat - - - 0.0000000002982 72.0
DTH2_k127_3975227_14 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000004852 65.0
DTH2_k127_3975227_2 Male sterility protein K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 514.0
DTH2_k127_3975227_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 520.0
DTH2_k127_3975227_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 513.0
DTH2_k127_3975227_5 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 431.0
DTH2_k127_3975227_6 response to heat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 397.0
DTH2_k127_3975227_7 metal-dependent enzyme K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 311.0
DTH2_k127_3975227_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000001198 240.0
DTH2_k127_3975227_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004122 216.0
DTH2_k127_4046888_0 FMN binding - - - 4.948e-207 648.0
DTH2_k127_4046888_1 L-glutamate biosynthetic process - - - 2.771e-198 622.0
DTH2_k127_4046888_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 395.0
DTH2_k127_4046888_3 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001149 281.0
DTH2_k127_4070639_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 3.4e-322 1002.0
DTH2_k127_4070639_1 PFAM Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 447.0
DTH2_k127_4070639_10 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000528 247.0
DTH2_k127_4070639_11 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000116 237.0
DTH2_k127_4070639_12 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000001895 223.0
DTH2_k127_4070639_13 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000009509 216.0
DTH2_k127_4070639_14 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000007101 201.0
DTH2_k127_4070639_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000005273 191.0
DTH2_k127_4070639_16 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000000000000000000366 184.0
DTH2_k127_4070639_17 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000004227 175.0
DTH2_k127_4070639_18 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000001748 163.0
DTH2_k127_4070639_19 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000003987 159.0
DTH2_k127_4070639_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 442.0
DTH2_k127_4070639_20 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000003521 156.0
DTH2_k127_4070639_21 TonB C terminal K03646 - - 0.0000002072 61.0
DTH2_k127_4070639_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 410.0
DTH2_k127_4070639_4 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 407.0
DTH2_k127_4070639_5 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 369.0
DTH2_k127_4070639_6 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 321.0
DTH2_k127_4070639_7 Belongs to the precorrin methyltransferase family K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003498 283.0
DTH2_k127_4070639_8 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004074 259.0
DTH2_k127_4070639_9 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 267.0
DTH2_k127_4122244_0 Belongs to the peptidase S16 family - - - 1.921e-244 779.0
DTH2_k127_4122244_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 509.0
DTH2_k127_4122244_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 323.0
DTH2_k127_4122244_3 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000958 283.0
DTH2_k127_4122244_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000001343 265.0
DTH2_k127_4137477_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 332.0
DTH2_k127_4137477_1 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 314.0
DTH2_k127_4137477_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 293.0
DTH2_k127_4137477_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 289.0
DTH2_k127_4137477_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 285.0
DTH2_k127_4137477_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000000000003611 158.0
DTH2_k127_4137477_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000001083 134.0
DTH2_k127_4137477_7 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000005744 96.0
DTH2_k127_4196826_0 carbon starvation protein CstA K06200 - - 1.488e-289 900.0
DTH2_k127_4196826_1 Periplasmic sensor domain - - - 5.323e-201 661.0
DTH2_k127_4196826_10 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
DTH2_k127_4196826_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 319.0
DTH2_k127_4196826_12 biosynthesis glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 302.0
DTH2_k127_4196826_13 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 301.0
DTH2_k127_4196826_14 PUA-like domain K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000004513 263.0
DTH2_k127_4196826_15 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001275 249.0
DTH2_k127_4196826_16 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000003022 235.0
DTH2_k127_4196826_17 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000002446 226.0
DTH2_k127_4196826_18 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000004639 222.0
DTH2_k127_4196826_19 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000003829 215.0
DTH2_k127_4196826_2 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 565.0
DTH2_k127_4196826_20 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000007823 219.0
DTH2_k127_4196826_21 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000004464 168.0
DTH2_k127_4196826_22 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000195 165.0
DTH2_k127_4196826_23 - - - - 0.000000000000000000000000000000001348 141.0
DTH2_k127_4196826_24 - - - - 0.0000000000000000000000000000001789 134.0
DTH2_k127_4196826_25 Hydrolase of alkaline phosphatase superfamily K07014 - - 0.0000000000000000000000001401 111.0
DTH2_k127_4196826_26 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000007669 70.0
DTH2_k127_4196826_27 - - - - 0.000000002053 58.0
DTH2_k127_4196826_28 - - - - 0.0000002637 54.0
DTH2_k127_4196826_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000001215 57.0
DTH2_k127_4196826_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 572.0
DTH2_k127_4196826_30 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0009685 48.0
DTH2_k127_4196826_4 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 527.0
DTH2_k127_4196826_5 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 516.0
DTH2_k127_4196826_6 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 494.0
DTH2_k127_4196826_7 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 476.0
DTH2_k127_4196826_8 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 460.0
DTH2_k127_4196826_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 364.0
DTH2_k127_4211333_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.02e-319 993.0
DTH2_k127_4211333_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.244e-233 730.0
DTH2_k127_4211333_10 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000001698 136.0
DTH2_k127_4211333_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.388e-201 634.0
DTH2_k127_4211333_3 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 433.0
DTH2_k127_4211333_4 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 419.0
DTH2_k127_4211333_5 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
DTH2_k127_4211333_6 - - - - 0.000000000000000000000000000000000000000000000000004382 185.0
DTH2_k127_4211333_7 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000001102 182.0
DTH2_k127_4211333_8 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000267 165.0
DTH2_k127_4211333_9 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000002666 141.0
DTH2_k127_4222022_0 COG1042 Acyl-CoA synthetase (NDP forming) K01905,K22224 - 6.2.1.13 5.128e-221 708.0
DTH2_k127_4222022_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003934 243.0
DTH2_k127_4222022_2 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000003456 209.0
DTH2_k127_4222022_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000002587 156.0
DTH2_k127_4266115_0 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 540.0
DTH2_k127_4266115_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
DTH2_k127_4266115_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 312.0
DTH2_k127_4266115_3 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 287.0
DTH2_k127_4266115_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000005704 193.0
DTH2_k127_4266115_5 methyltransferase - - - 0.0000000000000000000000000000000000000001316 158.0
DTH2_k127_4266115_6 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000009767 136.0
DTH2_k127_4266115_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002142 68.0
DTH2_k127_4266115_8 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000007952 59.0
DTH2_k127_4305954_0 - - - - 0.000000000000005468 84.0
DTH2_k127_4305954_1 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.000000000002902 79.0
DTH2_k127_4305954_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000004289 63.0
DTH2_k127_4305954_3 Domain of unknown function (DUF4384) - - - 0.0000235 53.0
DTH2_k127_4332059_0 Von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 469.0
DTH2_k127_4332059_1 CbbQ/NirQ/NorQ C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 398.0
DTH2_k127_4332059_2 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 362.0
DTH2_k127_4332059_3 dioxygenase K15777 - - 0.0000000000000000000009324 97.0
DTH2_k127_4398329_0 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 539.0
DTH2_k127_4398329_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 528.0
DTH2_k127_4398329_10 Restriction endonuclease XhoI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006948 271.0
DTH2_k127_4398329_11 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006154 263.0
DTH2_k127_4398329_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 251.0
DTH2_k127_4398329_13 PFAM amino acid permease-associated region K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000007364 239.0
DTH2_k127_4398329_14 lytic transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000007201 251.0
DTH2_k127_4398329_15 - - - - 0.000000000000000000000000000000000000000000000000000000000003675 218.0
DTH2_k127_4398329_16 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000002412 173.0
DTH2_k127_4398329_17 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000002762 173.0
DTH2_k127_4398329_18 NosL - - - 0.0000000000000000000000000000000000000000009382 163.0
DTH2_k127_4398329_19 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000398 162.0
DTH2_k127_4398329_2 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 496.0
DTH2_k127_4398329_20 PFAM pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000008155 149.0
DTH2_k127_4398329_21 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03774,K03775 - 5.2.1.8 0.000000000000000000000000000000000005886 145.0
DTH2_k127_4398329_22 Membrane - - - 0.0000000000000000000000000000000000456 138.0
DTH2_k127_4398329_23 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K07003 - - 0.0000000000000000000000000000553 124.0
DTH2_k127_4398329_24 Transcriptional regulator, LysR - - - 0.0000000000000001189 89.0
DTH2_k127_4398329_3 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 491.0
DTH2_k127_4398329_4 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 394.0
DTH2_k127_4398329_5 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 391.0
DTH2_k127_4398329_6 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 376.0
DTH2_k127_4398329_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 361.0
DTH2_k127_4398329_8 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 358.0
DTH2_k127_4398329_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
DTH2_k127_4432595_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.287e-235 749.0
DTH2_k127_4432595_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 505.0
DTH2_k127_4432595_2 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 444.0
DTH2_k127_4432595_3 - - - - 0.0000000000000000000000000000000000000000000003766 170.0
DTH2_k127_4432595_4 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000001046 167.0
DTH2_k127_4432595_5 response regulator - - - 0.00000000000000000000000000000000000008069 147.0
DTH2_k127_4432595_6 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000003609 152.0
DTH2_k127_4432595_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000001935 142.0
DTH2_k127_4432595_8 Histidine kinase - - - 0.000000000000000000000003853 111.0
DTH2_k127_4432595_9 phosphorelay signal transduction system - - - 0.00000000000000000000005907 106.0
DTH2_k127_4523871_0 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 555.0
DTH2_k127_4523871_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000001187 207.0
DTH2_k127_4540183_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1e-323 1008.0
DTH2_k127_4540183_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 5.4e-323 1012.0
DTH2_k127_4540183_10 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003236 266.0
DTH2_k127_4540183_11 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000398 252.0
DTH2_k127_4540183_12 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000001442 235.0
DTH2_k127_4540183_13 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000003046 165.0
DTH2_k127_4540183_14 - - - - 0.00000000000000000000000000009967 119.0
DTH2_k127_4540183_15 Membrane - - - 0.00000000000000000004888 95.0
DTH2_k127_4540183_16 PFAM translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000472 81.0
DTH2_k127_4540183_17 transcriptional regulator K03892 - - 0.000000000000001917 81.0
DTH2_k127_4540183_18 - - - - 0.00000000000101 74.0
DTH2_k127_4540183_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.441e-223 699.0
DTH2_k127_4540183_3 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 489.0
DTH2_k127_4540183_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 467.0
DTH2_k127_4540183_5 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 391.0
DTH2_k127_4540183_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 356.0
DTH2_k127_4540183_7 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 323.0
DTH2_k127_4540183_8 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004457 281.0
DTH2_k127_4540183_9 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 261.0
DTH2_k127_4552638_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 548.0
DTH2_k127_4552638_1 purine nucleobase transmembrane transporter activity K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 529.0
DTH2_k127_4552638_10 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000874 226.0
DTH2_k127_4552638_11 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000009093 238.0
DTH2_k127_4552638_12 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000007369 198.0
DTH2_k127_4552638_13 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000003601 180.0
DTH2_k127_4552638_14 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000000000009906 168.0
DTH2_k127_4552638_15 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000001411 169.0
DTH2_k127_4552638_16 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000000000001644 164.0
DTH2_k127_4552638_17 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000227 154.0
DTH2_k127_4552638_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.0000000000000000000000000000000001954 139.0
DTH2_k127_4552638_19 Type II secretion system protein B K02451 - - 0.00000000000000000000000009541 118.0
DTH2_k127_4552638_2 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 525.0
DTH2_k127_4552638_20 - - - - 0.0000000001826 66.0
DTH2_k127_4552638_21 restriction endonuclease K07448 - - 0.00006513 47.0
DTH2_k127_4552638_3 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 520.0
DTH2_k127_4552638_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 428.0
DTH2_k127_4552638_5 Dehydrogenase E1 component K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 405.0
DTH2_k127_4552638_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 376.0
DTH2_k127_4552638_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 359.0
DTH2_k127_4552638_8 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000223 271.0
DTH2_k127_4552638_9 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000004567 240.0
DTH2_k127_4581738_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1825.0
DTH2_k127_4581738_1 GTP-binding protein TypA K06207 - - 3.888e-266 833.0
DTH2_k127_4581738_10 mechanosensitive ion channel K03442,K16052 - - 0.000001215 57.0
DTH2_k127_4581738_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0001414 46.0
DTH2_k127_4581738_2 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 610.0
DTH2_k127_4581738_3 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 502.0
DTH2_k127_4581738_4 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 299.0
DTH2_k127_4581738_5 Mechanosensitive ion channel K03442 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001273 268.0
DTH2_k127_4581738_6 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000005532 225.0
DTH2_k127_4581738_7 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000004803 196.0
DTH2_k127_4581738_8 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000006966 128.0
DTH2_k127_4581738_9 membrane - - - 0.0000000000000000000000000002131 121.0
DTH2_k127_4687912_0 CARDB domain-containing protein,subtilase family protease - - - 2.932e-233 760.0
DTH2_k127_4687912_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.913e-197 622.0
DTH2_k127_4687912_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000001306 191.0
DTH2_k127_4687912_12 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000001682 140.0
DTH2_k127_4687912_13 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000002203 137.0
DTH2_k127_4687912_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000004335 126.0
DTH2_k127_4687912_15 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000005995 109.0
DTH2_k127_4687912_17 Histidine kinase A domain protein K02482,K14986 - 2.7.13.3 0.000000000000000007089 84.0
DTH2_k127_4687912_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 454.0
DTH2_k127_4687912_3 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 406.0
DTH2_k127_4687912_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 385.0
DTH2_k127_4687912_5 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 395.0
DTH2_k127_4687912_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 355.0
DTH2_k127_4687912_7 PFAM 4Fe-4S dicluster domain K04014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 347.0
DTH2_k127_4687912_8 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 311.0
DTH2_k127_4687912_9 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003246 258.0
DTH2_k127_4797998_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 357.0
DTH2_k127_4797998_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 378.0
DTH2_k127_4797998_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 355.0
DTH2_k127_4797998_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000007152 251.0
DTH2_k127_4803390_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 2.234e-288 911.0
DTH2_k127_4803390_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 546.0
DTH2_k127_4803390_2 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 357.0
DTH2_k127_4803390_3 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 308.0
DTH2_k127_4803390_4 Cold shock K03704 - - 0.000000000000000000000001159 106.0
DTH2_k127_4803390_6 belongs to the CobB CobQ family K06873 - - 0.00005159 46.0
DTH2_k127_4832944_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 329.0
DTH2_k127_4832944_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000764 262.0
DTH2_k127_4832944_2 Belongs to the sirtuin family. Class K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003071 264.0
DTH2_k127_4832944_4 Copper resistance protein CopZ K07213 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0002151 48.0
DTH2_k127_4841813_0 Heat shock protein 70 family - - - 7.675e-206 657.0
DTH2_k127_4841813_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 538.0
DTH2_k127_4841813_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 422.0
DTH2_k127_4841813_3 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 382.0
DTH2_k127_4841813_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000001177 213.0
DTH2_k127_4841813_5 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000002883 146.0
DTH2_k127_4952843_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1067.0
DTH2_k127_4952843_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 8.826e-248 775.0
DTH2_k127_4952843_10 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 457.0
DTH2_k127_4952843_11 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 453.0
DTH2_k127_4952843_12 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 444.0
DTH2_k127_4952843_13 Bacterial regulatory protein, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 429.0
DTH2_k127_4952843_14 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 421.0
DTH2_k127_4952843_15 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 407.0
DTH2_k127_4952843_16 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 340.0
DTH2_k127_4952843_17 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000008267 272.0
DTH2_k127_4952843_18 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001816 266.0
DTH2_k127_4952843_19 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001186 258.0
DTH2_k127_4952843_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.014e-231 730.0
DTH2_k127_4952843_20 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001347 258.0
DTH2_k127_4952843_21 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
DTH2_k127_4952843_22 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000008209 231.0
DTH2_k127_4952843_23 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000009005 227.0
DTH2_k127_4952843_24 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000001653 222.0
DTH2_k127_4952843_25 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000454 213.0
DTH2_k127_4952843_26 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000004643 210.0
DTH2_k127_4952843_27 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000004785 192.0
DTH2_k127_4952843_28 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000003307 193.0
DTH2_k127_4952843_29 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000003814 171.0
DTH2_k127_4952843_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 9.131e-218 687.0
DTH2_k127_4952843_30 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000001115 168.0
DTH2_k127_4952843_31 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000000000000000002047 154.0
DTH2_k127_4952843_32 Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000003847 151.0
DTH2_k127_4952843_33 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000001182 138.0
DTH2_k127_4952843_34 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000006441 129.0
DTH2_k127_4952843_35 LysM domain - - - 0.000000000000000000000000000002387 132.0
DTH2_k127_4952843_36 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000000003926 120.0
DTH2_k127_4952843_38 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000001572 118.0
DTH2_k127_4952843_39 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000003233 116.0
DTH2_k127_4952843_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 3.306e-194 614.0
DTH2_k127_4952843_40 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000002812 111.0
DTH2_k127_4952843_41 electron transfer activity K05337,K17247 - - 0.000000000000000000000002957 103.0
DTH2_k127_4952843_43 - - - - 0.000000000000000000003869 96.0
DTH2_k127_4952843_5 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 562.0
DTH2_k127_4952843_6 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 573.0
DTH2_k127_4952843_7 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 535.0
DTH2_k127_4952843_8 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 504.0
DTH2_k127_4952843_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 493.0
DTH2_k127_49629_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 1.441e-299 925.0
DTH2_k127_49629_1 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 9.495e-218 685.0
DTH2_k127_49629_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000002541 150.0
DTH2_k127_49629_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000005152 140.0
DTH2_k127_49629_12 PFAM regulatory protein, LysR - - - 0.0000000000000000000000129 108.0
DTH2_k127_49629_13 MacB-like periplasmic core domain K02004 - - 0.0000000000122 66.0
DTH2_k127_49629_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 533.0
DTH2_k127_49629_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K05588 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 439.0
DTH2_k127_49629_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 417.0
DTH2_k127_49629_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001314 275.0
DTH2_k127_49629_6 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000004336 262.0
DTH2_k127_49629_7 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000008724 267.0
DTH2_k127_49629_8 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000004057 211.0
DTH2_k127_49629_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001616 197.0
DTH2_k127_5079883_0 DNA polymerase K02347 - - 1.983e-242 760.0
DTH2_k127_5079883_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 8.633e-232 729.0
DTH2_k127_5079883_10 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 451.0
DTH2_k127_5079883_11 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 341.0
DTH2_k127_5079883_12 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 342.0
DTH2_k127_5079883_13 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 301.0
DTH2_k127_5079883_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
DTH2_k127_5079883_15 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000001491 147.0
DTH2_k127_5079883_16 - - - - 0.0000000000000000000000000000004502 130.0
DTH2_k127_5079883_17 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.000000000000000000009119 92.0
DTH2_k127_5079883_18 - - - - 0.00000000000222 70.0
DTH2_k127_5079883_19 - - - - 0.0000000007431 61.0
DTH2_k127_5079883_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 8.974e-198 622.0
DTH2_k127_5079883_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 4.246e-196 619.0
DTH2_k127_5079883_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 608.0
DTH2_k127_5079883_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 603.0
DTH2_k127_5079883_6 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 567.0
DTH2_k127_5079883_7 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 534.0
DTH2_k127_5079883_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 526.0
DTH2_k127_5079883_9 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 511.0
DTH2_k127_5160552_0 CHASE2 K01768 - 4.6.1.1 5.82e-212 684.0
DTH2_k127_5160552_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 415.0
DTH2_k127_5160552_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002885 260.0
DTH2_k127_5160552_3 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000005262 59.0
DTH2_k127_5177009_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 514.0
DTH2_k127_5177009_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 409.0
DTH2_k127_5177009_2 smart pdz dhr glgf - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 289.0
DTH2_k127_5177009_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000004144 231.0
DTH2_k127_5177009_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000001484 213.0
DTH2_k127_5177009_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000007824 127.0
DTH2_k127_5177839_0 ABC transporter K06158 - - 1.778e-230 729.0
DTH2_k127_5177839_1 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 558.0
DTH2_k127_5177839_10 PFAM amino acid-binding ACT domain protein - - - 0.00000000000002328 78.0
DTH2_k127_5177839_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000468 70.0
DTH2_k127_5177839_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 426.0
DTH2_k127_5177839_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 298.0
DTH2_k127_5177839_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000154 205.0
DTH2_k127_5177839_5 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000000000000000000000000000000000000000000000006615 178.0
DTH2_k127_5177839_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000001265 175.0
DTH2_k127_5177839_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000001594 147.0
DTH2_k127_5177839_8 protein complex oligomerization - - - 0.0000000000000000000000000000008066 128.0
DTH2_k127_5177839_9 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000000001567 113.0
DTH2_k127_5221655_0 40-residue yvtn family beta-propeller repeat protein - - - 3.181e-205 658.0
DTH2_k127_5221655_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 457.0
DTH2_k127_5221655_10 carbon dioxide binding K04653,K04654 - - 0.00000001116 60.0
DTH2_k127_5221655_11 His Kinase A (phosphoacceptor) domain - - - 0.0001648 53.0
DTH2_k127_5221655_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 345.0
DTH2_k127_5221655_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000225 246.0
DTH2_k127_5221655_4 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000006577 211.0
DTH2_k127_5221655_5 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000008972 173.0
DTH2_k127_5221655_6 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000000000000000000000002912 156.0
DTH2_k127_5221655_7 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000007363 126.0
DTH2_k127_5221655_8 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000002534 122.0
DTH2_k127_5221655_9 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.00000000000002 76.0
DTH2_k127_5229009_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 447.0
DTH2_k127_5229009_1 Potassium K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 412.0
DTH2_k127_5229009_2 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000001497 228.0
DTH2_k127_5229009_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000009395 213.0
DTH2_k127_5229009_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000008325 171.0
DTH2_k127_5229009_5 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000001377 130.0
DTH2_k127_5229009_6 PFAM CBS domain containing protein - - - 0.00000002126 63.0
DTH2_k127_5307601_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 7.192e-221 700.0
DTH2_k127_5307601_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001429 248.0
DTH2_k127_5307601_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00007884 45.0
DTH2_k127_5333853_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.008e-258 807.0
DTH2_k127_5333853_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 612.0
DTH2_k127_5333853_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 427.0
DTH2_k127_5333853_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
DTH2_k127_5333853_4 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 331.0
DTH2_k127_5333853_5 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 316.0
DTH2_k127_5333853_6 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000001293 223.0
DTH2_k127_5333853_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000008556 205.0
DTH2_k127_5333853_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.0000000000000000000000000000001822 132.0
DTH2_k127_53871_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 563.0
DTH2_k127_53871_1 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 549.0
DTH2_k127_53871_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000006823 175.0
DTH2_k127_53871_3 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000004043 166.0
DTH2_k127_5388302_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.019e-223 697.0
DTH2_k127_5388302_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 407.0
DTH2_k127_5388302_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
DTH2_k127_5388302_11 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000001603 231.0
DTH2_k127_5388302_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003484 228.0
DTH2_k127_5388302_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002778 201.0
DTH2_k127_5388302_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005886 194.0
DTH2_k127_5388302_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001049 195.0
DTH2_k127_5388302_16 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000004247 177.0
DTH2_k127_5388302_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000004317 172.0
DTH2_k127_5388302_18 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000006038 175.0
DTH2_k127_5388302_19 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000006759 157.0
DTH2_k127_5388302_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 369.0
DTH2_k127_5388302_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001436 157.0
DTH2_k127_5388302_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000006604 155.0
DTH2_k127_5388302_22 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000306 151.0
DTH2_k127_5388302_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000005352 151.0
DTH2_k127_5388302_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001292 130.0
DTH2_k127_5388302_25 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003406 113.0
DTH2_k127_5388302_26 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001038 108.0
DTH2_k127_5388302_27 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000003218 84.0
DTH2_k127_5388302_28 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001722 70.0
DTH2_k127_5388302_3 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 353.0
DTH2_k127_5388302_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 342.0
DTH2_k127_5388302_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 328.0
DTH2_k127_5388302_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 300.0
DTH2_k127_5388302_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
DTH2_k127_5388302_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000005765 244.0
DTH2_k127_5388302_9 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000007743 239.0
DTH2_k127_5396968_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.308e-215 677.0
DTH2_k127_5396968_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.264e-195 621.0
DTH2_k127_5396968_10 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.0000000000000000000000000000000000000001211 156.0
DTH2_k127_5396968_11 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000002271 152.0
DTH2_k127_5396968_12 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000005024 114.0
DTH2_k127_5396968_13 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000001707 106.0
DTH2_k127_5396968_14 - - - - 0.00000000000000000009854 94.0
DTH2_k127_5396968_15 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000001867 84.0
DTH2_k127_5396968_16 Putative MetA-pathway of phenol degradation - - - 0.0000000000000615 75.0
DTH2_k127_5396968_18 - - - - 0.0000009344 54.0
DTH2_k127_5396968_19 Domain of unknown function (DUF4198) - - - 0.000001205 61.0
DTH2_k127_5396968_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 427.0
DTH2_k127_5396968_3 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 410.0
DTH2_k127_5396968_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 349.0
DTH2_k127_5396968_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 318.0
DTH2_k127_5396968_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 279.0
DTH2_k127_5396968_7 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000002631 221.0
DTH2_k127_5396968_8 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000181 201.0
DTH2_k127_5396968_9 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000002509 168.0
DTH2_k127_5412834_0 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 391.0
DTH2_k127_5412834_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 323.0
DTH2_k127_5412834_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 312.0
DTH2_k127_5412834_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 229.0
DTH2_k127_5412834_4 2 iron, 2 sulfur cluster binding K01465,K02823,K05784,K17828 - 1.3.1.14,3.5.2.3 0.000000000000000000000000000000000000000000000000000000001007 209.0
DTH2_k127_5412834_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000003867 203.0
DTH2_k127_5412834_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000002033 192.0
DTH2_k127_5412834_7 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000002899 176.0
DTH2_k127_5412834_8 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000002015 152.0
DTH2_k127_5412834_9 - - - - 0.00000000000004385 73.0
DTH2_k127_5421025_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1235.0
DTH2_k127_5421025_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.262e-291 904.0
DTH2_k127_5421025_10 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 415.0
DTH2_k127_5421025_11 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 407.0
DTH2_k127_5421025_12 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 418.0
DTH2_k127_5421025_13 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 408.0
DTH2_k127_5421025_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 394.0
DTH2_k127_5421025_15 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 379.0
DTH2_k127_5421025_16 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 376.0
DTH2_k127_5421025_17 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 346.0
DTH2_k127_5421025_18 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 348.0
DTH2_k127_5421025_19 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 340.0
DTH2_k127_5421025_2 PFAM Radical SAM - - - 6.957e-208 657.0
DTH2_k127_5421025_20 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 319.0
DTH2_k127_5421025_21 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 311.0
DTH2_k127_5421025_22 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 294.0
DTH2_k127_5421025_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001576 267.0
DTH2_k127_5421025_24 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
DTH2_k127_5421025_25 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001244 226.0
DTH2_k127_5421025_26 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000003126 213.0
DTH2_k127_5421025_27 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000003068 198.0
DTH2_k127_5421025_28 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000007994 196.0
DTH2_k127_5421025_29 LemA family K03744 - - 0.00000000000000000000000000000000000000000000004771 176.0
DTH2_k127_5421025_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 601.0
DTH2_k127_5421025_30 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000001768 141.0
DTH2_k127_5421025_31 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000002487 133.0
DTH2_k127_5421025_32 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000002428 121.0
DTH2_k127_5421025_33 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000001231 98.0
DTH2_k127_5421025_34 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001196 85.0
DTH2_k127_5421025_35 - - - - 0.000000000000000144 81.0
DTH2_k127_5421025_36 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000006093 78.0
DTH2_k127_5421025_37 Sporulation and spore germination - - - 0.0000004227 59.0
DTH2_k127_5421025_38 Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein K08364 - - 0.0000005619 53.0
DTH2_k127_5421025_39 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000004863 58.0
DTH2_k127_5421025_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 598.0
DTH2_k127_5421025_40 E3 Ubiquitin ligase - - - 0.0004141 52.0
DTH2_k127_5421025_41 His Kinase A (phosphoacceptor) domain - - - 0.0005153 50.0
DTH2_k127_5421025_5 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 475.0
DTH2_k127_5421025_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 464.0
DTH2_k127_5421025_7 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 429.0
DTH2_k127_5421025_8 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 433.0
DTH2_k127_5421025_9 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 416.0
DTH2_k127_5475832_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.886e-196 621.0
DTH2_k127_5475832_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 563.0
DTH2_k127_5475832_2 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 385.0
DTH2_k127_5475832_3 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 330.0
DTH2_k127_5475832_4 PFAM Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 313.0
DTH2_k127_5475832_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000004967 149.0
DTH2_k127_5475832_6 - - - - 0.00000000000004268 77.0
DTH2_k127_5475832_7 Domain of unknown function (DUF4912) K09942 - - 0.00000000001123 76.0
DTH2_k127_5475832_8 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 0.000001546 54.0
DTH2_k127_5511480_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 595.0
DTH2_k127_5511480_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 374.0
DTH2_k127_5511480_2 DNA polymerase A domain K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
DTH2_k127_5511480_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005351 257.0
DTH2_k127_5511480_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000003058 192.0
DTH2_k127_5511480_5 PFAM transposase IS4 family protein - - - 0.000000004609 59.0
DTH2_k127_5538493_0 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 433.0
DTH2_k127_5538493_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 294.0
DTH2_k127_5538493_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
DTH2_k127_5538493_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000003767 250.0
DTH2_k127_5538493_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000004393 134.0
DTH2_k127_5538493_5 Protein conserved in bacteria K11719 - - 0.00001865 53.0
DTH2_k127_5538493_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00001872 47.0
DTH2_k127_5548565_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 490.0
DTH2_k127_5548565_1 epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 309.0
DTH2_k127_5548565_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 292.0
DTH2_k127_5548565_3 - - - - 0.00000000000000000000000000000000000000002244 158.0
DTH2_k127_5583044_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1034.0
DTH2_k127_5583044_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 421.0
DTH2_k127_5583044_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000002644 239.0
DTH2_k127_5583044_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000005928 228.0
DTH2_k127_5583044_4 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000003216 157.0
DTH2_k127_5583044_5 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000001506 141.0
DTH2_k127_5583044_6 belongs to the thioredoxin family K03671 - - 0.00001897 49.0
DTH2_k127_5688382_0 mechanosensitive ion channel K05802 - - 2.881e-239 781.0
DTH2_k127_5812882_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1285.0
DTH2_k127_5812882_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 568.0
DTH2_k127_5812882_2 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 517.0
DTH2_k127_5812882_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 413.0
DTH2_k127_5812882_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 310.0
DTH2_k127_5812882_5 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000756 284.0
DTH2_k127_5812882_6 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000000000000000000000000004353 179.0
DTH2_k127_5812882_7 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000003878 140.0
DTH2_k127_5824363_0 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 464.0
DTH2_k127_5824363_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 329.0
DTH2_k127_6006029_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 466.0
DTH2_k127_6006029_1 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 314.0
DTH2_k127_6006029_2 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000005025 184.0
DTH2_k127_6006029_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000001153 201.0
DTH2_k127_6075855_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0 1145.0
DTH2_k127_6075855_1 Aconitase C-terminal domain K01681 - 4.2.1.3 6.7e-288 896.0
DTH2_k127_6075855_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 563.0
DTH2_k127_6075855_3 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 515.0
DTH2_k127_6075855_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 472.0
DTH2_k127_6075855_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 347.0
DTH2_k127_6075855_6 Thioredoxin-like - - - 0.0000000000000000000000000000000000002192 148.0
DTH2_k127_6147726_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 510.0
DTH2_k127_6147726_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 440.0
DTH2_k127_6147726_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 369.0
DTH2_k127_6147726_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 340.0
DTH2_k127_6147726_4 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
DTH2_k127_6147726_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 306.0
DTH2_k127_6147726_6 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000000000000000000000000002358 192.0
DTH2_k127_6147726_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000378 94.0
DTH2_k127_6376789_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 315.0
DTH2_k127_6376789_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 289.0
DTH2_k127_6376789_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001461 268.0
DTH2_k127_6376789_3 chorismate mutase K04782 - 4.2.99.21 0.0000000000000000000000000000000002822 134.0
DTH2_k127_6376789_4 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.00000000000000007621 83.0
DTH2_k127_6376789_5 PFAM Mammalian cell entry related K02067 - - 0.000000000000003073 86.0
DTH2_k127_6376789_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000002005 71.0
DTH2_k127_6376789_7 isoprenoid biosynthetic process - - - 0.0000000243 59.0
DTH2_k127_6376789_8 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0009782 49.0
DTH2_k127_643008_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1043.0
DTH2_k127_643008_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.239e-226 723.0
DTH2_k127_643008_2 PFAM Major Facilitator Superfamily K08177 - - 5.727e-213 668.0
DTH2_k127_643008_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 589.0
DTH2_k127_643008_4 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 409.0
DTH2_k127_643008_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005379 280.0
DTH2_k127_643008_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000002889 248.0
DTH2_k127_643008_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000005846 243.0
DTH2_k127_643008_8 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0000000000000001402 81.0
DTH2_k127_6490028_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.162e-241 758.0
DTH2_k127_6490028_1 Fructose-bisphosphate aldolase class-II - - - 5.774e-210 660.0
DTH2_k127_6490028_10 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000008202 181.0
DTH2_k127_6490028_11 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000003781 177.0
DTH2_k127_6490028_12 acetyltransferase - - - 0.00000000000000000000000000000000001273 141.0
DTH2_k127_6490028_13 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000001373 129.0
DTH2_k127_6490028_14 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000002268 119.0
DTH2_k127_6490028_15 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000001873 110.0
DTH2_k127_6490028_16 Zinc finger cdgsh-type domain protein - - - 0.0000000000000000000000000446 108.0
DTH2_k127_6490028_17 PFAM Fimbrial assembly K02461 - - 0.0000000000000000000000006398 120.0
DTH2_k127_6490028_18 Universal stress protein family K07090 - - 0.00000000000972 76.0
DTH2_k127_6490028_19 pilus assembly protein PilW K02459,K02672 - - 0.00000000006526 71.0
DTH2_k127_6490028_2 PFAM magnesium chelatase ChlI subunit K07391 - - 1.509e-208 659.0
DTH2_k127_6490028_20 CAAX protease self-immunity - - - 0.000000001066 67.0
DTH2_k127_6490028_21 type IV pilus modification protein PilV K02458,K02671 - - 0.000000003085 63.0
DTH2_k127_6490028_22 COG4970 Tfp pilus assembly protein FimT K02457 - - 0.0000003119 59.0
DTH2_k127_6490028_23 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000007529 52.0
DTH2_k127_6490028_24 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000296 56.0
DTH2_k127_6490028_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 6.5e-203 639.0
DTH2_k127_6490028_4 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 569.0
DTH2_k127_6490028_5 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 515.0
DTH2_k127_6490028_6 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 393.0
DTH2_k127_6490028_7 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 361.0
DTH2_k127_6490028_8 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 310.0
DTH2_k127_6490028_9 radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
DTH2_k127_6525117_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 569.0
DTH2_k127_6525117_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 545.0
DTH2_k127_6525117_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 317.0
DTH2_k127_6525117_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000002171 140.0
DTH2_k127_6525117_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000323 115.0
DTH2_k127_6525117_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000004191 96.0
DTH2_k127_6575003_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.133e-311 972.0
DTH2_k127_6575003_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.013e-296 923.0
DTH2_k127_6575003_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 456.0
DTH2_k127_6575003_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 444.0
DTH2_k127_6575003_12 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 398.0
DTH2_k127_6575003_13 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 361.0
DTH2_k127_6575003_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 361.0
DTH2_k127_6575003_15 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 341.0
DTH2_k127_6575003_16 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 342.0
DTH2_k127_6575003_17 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 328.0
DTH2_k127_6575003_18 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 325.0
DTH2_k127_6575003_19 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 334.0
DTH2_k127_6575003_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.419e-261 825.0
DTH2_k127_6575003_20 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 310.0
DTH2_k127_6575003_21 Thymidylate synthase complementing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 305.0
DTH2_k127_6575003_22 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000149 289.0
DTH2_k127_6575003_23 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003967 280.0
DTH2_k127_6575003_24 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003114 260.0
DTH2_k127_6575003_25 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000001531 180.0
DTH2_k127_6575003_26 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000008472 184.0
DTH2_k127_6575003_27 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000001347 149.0
DTH2_k127_6575003_28 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000003363 135.0
DTH2_k127_6575003_29 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000000000000000000001443 144.0
DTH2_k127_6575003_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.856e-196 618.0
DTH2_k127_6575003_30 Thiamine-binding protein - - - 0.0000000000000000000000000000002052 125.0
DTH2_k127_6575003_31 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000005064 111.0
DTH2_k127_6575003_33 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001501 89.0
DTH2_k127_6575003_34 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.00000000000000002466 84.0
DTH2_k127_6575003_36 Protein of unknown function (DUF721) - - - 0.00000005086 61.0
DTH2_k127_6575003_4 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 610.0
DTH2_k127_6575003_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 579.0
DTH2_k127_6575003_6 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 568.0
DTH2_k127_6575003_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 555.0
DTH2_k127_6575003_8 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 491.0
DTH2_k127_6575003_9 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
DTH2_k127_6591953_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 434.0
DTH2_k127_6591953_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 369.0
DTH2_k127_6591953_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002483 286.0
DTH2_k127_6591953_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000001675 229.0
DTH2_k127_6591953_4 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000005083 105.0
DTH2_k127_6604587_0 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 584.0
DTH2_k127_6604587_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 490.0
DTH2_k127_6604587_2 Uncharacterized ACR, COG1678 - - - 0.00000000000000000000000000000000003352 144.0
DTH2_k127_6628344_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 494.0
DTH2_k127_6628344_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 349.0
DTH2_k127_6628344_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000001767 158.0
DTH2_k127_6628344_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000004204 134.0
DTH2_k127_6628344_4 protein conserved in bacteria K09928 - - 0.0000000000000001814 85.0
DTH2_k127_6807394_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1107.0
DTH2_k127_6807394_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 8.164e-202 644.0
DTH2_k127_6807394_10 Rubrerythrin - - - 0.0000000000000000000001303 103.0
DTH2_k127_6807394_12 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000001064 52.0
DTH2_k127_6807394_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 425.0
DTH2_k127_6807394_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 380.0
DTH2_k127_6807394_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 321.0
DTH2_k127_6807394_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 308.0
DTH2_k127_6807394_6 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
DTH2_k127_6807394_7 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000002894 209.0
DTH2_k127_6807394_8 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000004873 162.0
DTH2_k127_6807394_9 Putative regulatory protein - - - 0.000000000000000000000005605 104.0
DTH2_k127_6830275_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 7.004e-263 817.0
DTH2_k127_6830275_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.452e-221 691.0
DTH2_k127_6830275_10 response regulator - - - 0.000000000000000000000001483 108.0
DTH2_k127_6830275_11 YtkA-like - - - 0.0000000007025 64.0
DTH2_k127_6830275_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 415.0
DTH2_k127_6830275_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 370.0
DTH2_k127_6830275_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 300.0
DTH2_k127_6830275_5 Transcriptional regulatory protein, C terminal K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000049 246.0
DTH2_k127_6830275_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000001652 224.0
DTH2_k127_6830275_7 CTP:tRNA cytidylyltransferase activity K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000002649 219.0
DTH2_k127_6830275_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000005393 216.0
DTH2_k127_6830275_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000001608 184.0
DTH2_k127_6896155_0 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 479.0
DTH2_k127_6896155_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 416.0
DTH2_k127_6896155_10 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000003433 218.0
DTH2_k127_6896155_11 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000000001089 160.0
DTH2_k127_6896155_12 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000000001338 154.0
DTH2_k127_6896155_13 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000009869 150.0
DTH2_k127_6896155_14 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000002017 96.0
DTH2_k127_6896155_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 395.0
DTH2_k127_6896155_3 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 337.0
DTH2_k127_6896155_4 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 319.0
DTH2_k127_6896155_5 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 313.0
DTH2_k127_6896155_6 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000007317 254.0
DTH2_k127_6896155_7 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000001397 233.0
DTH2_k127_6896155_8 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000003455 232.0
DTH2_k127_6896155_9 radical SAM domain protein K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000001586 224.0
DTH2_k127_6898124_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 6.292e-288 895.0
DTH2_k127_6898124_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 541.0
DTH2_k127_6898124_10 short-chain dehydrogenase reductase SDR K05886 - 1.1.1.276 0.0000000000000000000000000000001766 132.0
DTH2_k127_6898124_12 Short C-terminal domain K08982 - - 0.000001791 50.0
DTH2_k127_6898124_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 482.0
DTH2_k127_6898124_3 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 486.0
DTH2_k127_6898124_4 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 451.0
DTH2_k127_6898124_5 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 351.0
DTH2_k127_6898124_6 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 304.0
DTH2_k127_6898124_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000249 171.0
DTH2_k127_6898124_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000004104 163.0
DTH2_k127_6898124_9 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000001674 172.0
DTH2_k127_6947336_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.533e-291 922.0
DTH2_k127_6947336_1 Neisseria PilC beta-propeller domain K02674 - - 3.022e-225 721.0
DTH2_k127_6947336_10 Prokaryotic N-terminal methylation motif - - - 0.000000000000000297 89.0
DTH2_k127_6947336_11 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000007554 79.0
DTH2_k127_6947336_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 305.0
DTH2_k127_6947336_3 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001792 262.0
DTH2_k127_6947336_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000004799 228.0
DTH2_k127_6947336_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000008929 213.0
DTH2_k127_6947336_6 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000005249 199.0
DTH2_k127_6947336_7 - - - - 0.0000000000000000000000000000000000000006487 156.0
DTH2_k127_6947336_8 COG3209 Rhs family protein - - - 0.000000000000000000000000000000001835 141.0
DTH2_k127_6947336_9 Pfam:N_methyl_2 K02671 - - 0.00000000000000008424 86.0
DTH2_k127_6966210_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.208e-295 923.0
DTH2_k127_6966210_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.994e-204 645.0
DTH2_k127_6966210_10 3-dehydroquinate dehydratase activity K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000002562 175.0
DTH2_k127_6966210_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002747 130.0
DTH2_k127_6966210_12 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000004043 94.0
DTH2_k127_6966210_13 Belongs to the UPF0434 family K09791 - - 0.00000000000000003835 82.0
DTH2_k127_6966210_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000001773 74.0
DTH2_k127_6966210_2 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 526.0
DTH2_k127_6966210_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 436.0
DTH2_k127_6966210_4 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 421.0
DTH2_k127_6966210_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 371.0
DTH2_k127_6966210_6 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 362.0
DTH2_k127_6966210_7 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 297.0
DTH2_k127_6966210_8 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001712 248.0
DTH2_k127_6966210_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000007039 205.0
DTH2_k127_6968435_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 532.0
DTH2_k127_6968435_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 458.0
DTH2_k127_6968435_10 SMART Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000000000000000000000000005134 201.0
DTH2_k127_6968435_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000457 181.0
DTH2_k127_6968435_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000001855 154.0
DTH2_k127_6968435_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000072 131.0
DTH2_k127_6968435_15 Protein of unknown function (DUF3617) - - - 0.0000000000000000005292 93.0
DTH2_k127_6968435_17 - - - - 0.00000000006828 67.0
DTH2_k127_6968435_18 Peptidoglycan-binding - - - 0.0000008514 52.0
DTH2_k127_6968435_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 417.0
DTH2_k127_6968435_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 383.0
DTH2_k127_6968435_4 response regulator K07664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 332.0
DTH2_k127_6968435_5 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 322.0
DTH2_k127_6968435_6 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 301.0
DTH2_k127_6968435_7 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000001748 245.0
DTH2_k127_6968435_8 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000001793 224.0
DTH2_k127_6968435_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000002958 194.0
DTH2_k127_698056_0 Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA K03498,K03499 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003728 277.0
DTH2_k127_698056_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000005496 217.0
DTH2_k127_698056_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000004435 172.0
DTH2_k127_698056_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000337 129.0
DTH2_k127_6999271_0 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000001847 214.0
DTH2_k127_6999271_1 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000000000000000000000000000002484 196.0
DTH2_k127_6999271_2 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000002201 128.0
DTH2_k127_6999271_3 Acetyltransferase - - - 0.000000000000000000000000001343 119.0
DTH2_k127_6999271_4 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000001614 93.0
DTH2_k127_6999271_5 Domain of unknown function (DUF3786) - - - 0.00000000000000001009 91.0
DTH2_k127_7111650_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 441.0
DTH2_k127_7111650_1 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 382.0
DTH2_k127_7111650_10 sulfur relay protein TusB DsrH K07237 - - 0.00001435 52.0
DTH2_k127_7111650_11 Tetratricopeptide repeat protein - - - 0.000122 53.0
DTH2_k127_7111650_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 389.0
DTH2_k127_7111650_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 321.0
DTH2_k127_7111650_4 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005003 254.0
DTH2_k127_7111650_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000425 203.0
DTH2_k127_7111650_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
DTH2_k127_7111650_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000001588 153.0
DTH2_k127_7111650_8 DsrE/DsrF-like family K07236 - - 0.0000004604 56.0
DTH2_k127_7111650_9 DsrE/DsrF-like family K07235 - - 0.000001866 52.0
DTH2_k127_7190859_0 Protein of unknown function (DUF2867) - - - 1.215e-198 629.0
DTH2_k127_7190859_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 569.0
DTH2_k127_7190859_2 PFAM Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 456.0
DTH2_k127_7190859_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 349.0
DTH2_k127_7190859_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 255.0
DTH2_k127_7190859_5 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001656 241.0
DTH2_k127_7190859_6 - - - - 0.00000000000000000000000000000000000000000000000000003528 194.0
DTH2_k127_7190859_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000001029 169.0
DTH2_k127_7336142_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.321e-204 658.0
DTH2_k127_7336142_1 Glycosyl transferase family 21 - - - 4.959e-197 629.0
DTH2_k127_7336142_10 Evidence 5 No homology to any previously reported sequences - - - 0.000004785 48.0
DTH2_k127_7336142_11 COG0457 FOG TPR repeat - - - 0.00001406 57.0
DTH2_k127_7336142_12 - - - - 0.0000644 49.0
DTH2_k127_7336142_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 563.0
DTH2_k127_7336142_3 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000003519 266.0
DTH2_k127_7336142_5 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006356 230.0
DTH2_k127_7336142_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000879 233.0
DTH2_k127_7336142_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000415 212.0
DTH2_k127_7336142_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000002946 106.0
DTH2_k127_7336142_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001413 79.0
DTH2_k127_7592237_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000001124 191.0
DTH2_k127_7592237_1 energy transducer activity K03832 - - 0.0000000000000000000000000000000000000000000000001852 180.0
DTH2_k127_7592237_2 - - - - 0.0000000000000000000000000000484 117.0
DTH2_k127_7592237_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000001525 124.0
DTH2_k127_7598685_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 1.257e-249 806.0
DTH2_k127_7598685_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000003508 228.0
DTH2_k127_7598685_2 Spermidine synthase tetramerisation domain K18787 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0009888,GO:0009914,GO:0009926,GO:0009987,GO:0010087,GO:0010089,GO:0010487,GO:0010817,GO:0016740,GO:0016765,GO:0016768,GO:0030154,GO:0032502,GO:0044424,GO:0044464,GO:0048759,GO:0048856,GO:0048869,GO:0051179,GO:0051234,GO:0060918,GO:0065007,GO:0065008,GO:1905177 2.5.1.79 0.000000000003701 69.0
DTH2_k127_7641252_0 GAF domain - - - 1.039e-239 772.0
DTH2_k127_7641252_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 561.0
DTH2_k127_7641252_10 transferase activity, transferring glycosyl groups K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007823 303.0
DTH2_k127_7641252_11 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 299.0
DTH2_k127_7641252_12 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 278.0
DTH2_k127_7641252_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001912 271.0
DTH2_k127_7641252_14 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000001495 244.0
DTH2_k127_7641252_15 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000007772 233.0
DTH2_k127_7641252_16 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000002512 224.0
DTH2_k127_7641252_17 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000005111 234.0
DTH2_k127_7641252_18 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000055 192.0
DTH2_k127_7641252_19 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000003488 121.0
DTH2_k127_7641252_2 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 495.0
DTH2_k127_7641252_20 protein with SCP PR1 domains - - - 0.000000000000000001073 94.0
DTH2_k127_7641252_21 O-antigen ligase K02847 - - 0.00000001083 66.0
DTH2_k127_7641252_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 492.0
DTH2_k127_7641252_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 481.0
DTH2_k127_7641252_5 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 375.0
DTH2_k127_7641252_6 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 373.0
DTH2_k127_7641252_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 345.0
DTH2_k127_7641252_8 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 332.0
DTH2_k127_7641252_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 314.0
DTH2_k127_7645898_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.982e-198 637.0
DTH2_k127_7645898_1 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 611.0
DTH2_k127_7645898_10 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000006316 241.0
DTH2_k127_7645898_11 PFAM Isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000001784 211.0
DTH2_k127_7645898_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000002889 186.0
DTH2_k127_7645898_13 translation release factor activity - - - 0.00000000000000000000000000000000000000000902 158.0
DTH2_k127_7645898_14 PFAM conserved K08316 - 2.1.1.171 0.000000000000000000000000000000306 130.0
DTH2_k127_7645898_15 part of a sulfur-relay system K11179 - - 0.00000000000000000000000001051 111.0
DTH2_k127_7645898_16 Psort location Cytoplasmic, score - - - 0.0000000000001611 83.0
DTH2_k127_7645898_17 - - - - 0.0000000000004076 77.0
DTH2_k127_7645898_2 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 582.0
DTH2_k127_7645898_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 517.0
DTH2_k127_7645898_4 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 460.0
DTH2_k127_7645898_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 413.0
DTH2_k127_7645898_6 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
DTH2_k127_7645898_7 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 401.0
DTH2_k127_7645898_8 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 398.0
DTH2_k127_7645898_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 328.0
DTH2_k127_7651190_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.881e-197 622.0
DTH2_k127_7651190_1 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 5.776e-195 615.0
DTH2_k127_7651190_2 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 531.0
DTH2_k127_7651190_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 508.0
DTH2_k127_7651190_4 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 293.0
DTH2_k127_7651190_5 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000642 199.0
DTH2_k127_7651190_6 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000002511 162.0
DTH2_k127_7651190_7 lyase activity - - - 0.00000000000000000000000000000000000002032 152.0
DTH2_k127_7651190_8 deoxyhypusine monooxygenase activity K05385 - - 0.00000000000000000002801 94.0
DTH2_k127_7651190_9 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000003749 82.0
DTH2_k127_7655590_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 522.0
DTH2_k127_7655590_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 479.0
DTH2_k127_7655590_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 341.0
DTH2_k127_7655590_3 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 327.0
DTH2_k127_7655590_4 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000206 153.0
DTH2_k127_76646_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.554e-300 929.0
DTH2_k127_76646_1 PBP superfamily domain K03750,K07219 - 2.10.1.1 9.724e-251 788.0
DTH2_k127_76646_10 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000001419 158.0
DTH2_k127_76646_11 - - - - 0.00000000000000000000000632 113.0
DTH2_k127_76646_12 Mut7-C ubiquitin - - - 0.000000000000000001933 87.0
DTH2_k127_76646_13 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000002318 80.0
DTH2_k127_76646_2 Iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 3.393e-200 628.0
DTH2_k127_76646_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 434.0
DTH2_k127_76646_4 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 356.0
DTH2_k127_76646_5 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 336.0
DTH2_k127_76646_6 LysM domain K01449,K19223 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000003829 269.0
DTH2_k127_76646_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000003698 200.0
DTH2_k127_76646_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000002152 186.0
DTH2_k127_76646_9 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000001306 158.0
DTH2_k127_7684718_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.049e-280 882.0
DTH2_k127_7684718_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.53e-229 721.0
DTH2_k127_7684718_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000007441 255.0
DTH2_k127_7684718_11 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000001231 230.0
DTH2_k127_7684718_12 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000002464 224.0
DTH2_k127_7684718_13 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000009258 216.0
DTH2_k127_7684718_14 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000001465 192.0
DTH2_k127_7684718_15 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000005805 199.0
DTH2_k127_7684718_16 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.0000000000000000000000000000000000000000000000001185 186.0
DTH2_k127_7684718_17 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000003257 169.0
DTH2_k127_7684718_18 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.0000000000000000000000000000001258 133.0
DTH2_k127_7684718_19 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000002836 118.0
DTH2_k127_7684718_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 608.0
DTH2_k127_7684718_20 sensor histidine kinase - - - 0.000000000000000000000006299 117.0
DTH2_k127_7684718_21 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000000001116 96.0
DTH2_k127_7684718_22 - - - - 0.00000000000008377 78.0
DTH2_k127_7684718_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 535.0
DTH2_k127_7684718_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 460.0
DTH2_k127_7684718_5 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 445.0
DTH2_k127_7684718_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 352.0
DTH2_k127_7684718_7 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 295.0
DTH2_k127_7684718_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 287.0
DTH2_k127_7684718_9 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 273.0
DTH2_k127_7711430_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 6.564e-229 719.0
DTH2_k127_7711430_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 534.0
DTH2_k127_7711430_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000004938 245.0
DTH2_k127_7711430_11 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000005194 166.0
DTH2_k127_7711430_12 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000005326 149.0
DTH2_k127_7711430_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 462.0
DTH2_k127_7711430_3 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 430.0
DTH2_k127_7711430_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 378.0
DTH2_k127_7711430_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 350.0
DTH2_k127_7711430_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 347.0
DTH2_k127_7711430_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 320.0
DTH2_k127_7711430_8 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 295.0
DTH2_k127_7711430_9 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001249 256.0
DTH2_k127_7769758_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.222e-221 692.0
DTH2_k127_7769758_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 357.0
DTH2_k127_7769758_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000003084 173.0
DTH2_k127_7769758_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000003694 126.0
DTH2_k127_7781160_0 Elongation factor G, domain IV K02355 - - 8.884e-318 986.0
DTH2_k127_7781160_1 pyruvate-flavodoxin oxidoreductase activity - - - 5.172e-301 931.0
DTH2_k127_7781160_10 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 292.0
DTH2_k127_7781160_11 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000003992 249.0
DTH2_k127_7781160_13 ThiS family K03636 - - 0.00000000000000000000000000000000001683 137.0
DTH2_k127_7781160_15 Protein of unknown function (DUF2799) - - - 0.000000000000000000000000000008327 130.0
DTH2_k127_7781160_16 NIL - - - 0.00000000000000000000000000002271 118.0
DTH2_k127_7781160_17 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000002662 123.0
DTH2_k127_7781160_18 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000000000008694 91.0
DTH2_k127_7781160_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.659e-251 785.0
DTH2_k127_7781160_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.456e-246 774.0
DTH2_k127_7781160_4 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 584.0
DTH2_k127_7781160_5 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 586.0
DTH2_k127_7781160_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 573.0
DTH2_k127_7781160_7 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
DTH2_k127_7781160_8 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 507.0
DTH2_k127_7781160_9 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 406.0
DTH2_k127_7804653_0 PFAM Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 491.0
DTH2_k127_7804653_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 395.0
DTH2_k127_7804653_2 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 318.0
DTH2_k127_7804653_3 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 319.0
DTH2_k127_7804653_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 306.0
DTH2_k127_7804653_5 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
DTH2_k127_7804653_6 TIGRFAM precorrin-2 C20-methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000009202 217.0
DTH2_k127_7804653_7 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000006225 197.0
DTH2_k127_7804653_8 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000002247 113.0
DTH2_k127_7804653_9 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000001167 102.0
DTH2_k127_7837692_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 6.123e-276 861.0
DTH2_k127_7837692_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 3.342e-235 743.0
DTH2_k127_7837692_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 296.0
DTH2_k127_7837692_11 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 292.0
DTH2_k127_7837692_12 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002544 283.0
DTH2_k127_7837692_13 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006635 257.0
DTH2_k127_7837692_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000001092 244.0
DTH2_k127_7837692_15 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000000000000000000000000918 241.0
DTH2_k127_7837692_16 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000005432 220.0
DTH2_k127_7837692_17 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000001398 216.0
DTH2_k127_7837692_18 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000002082 181.0
DTH2_k127_7837692_19 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000001575 178.0
DTH2_k127_7837692_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 1.74e-211 679.0
DTH2_k127_7837692_20 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.000000000000000000000000000000000000000002506 162.0
DTH2_k127_7837692_21 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000005888 147.0
DTH2_k127_7837692_22 Protein of unknown function (DUF1284) K09706 - - 0.0000000000000000000000000000000000006063 143.0
DTH2_k127_7837692_23 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000008119 143.0
DTH2_k127_7837692_24 PFAM RES domain - - - 0.0000000000000000000000000000000002373 138.0
DTH2_k127_7837692_25 bacterial (prokaryotic) histone like domain K04764 - - 0.00000000000000000000000000003356 120.0
DTH2_k127_7837692_26 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000009445 119.0
DTH2_k127_7837692_27 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000008093 104.0
DTH2_k127_7837692_28 sequence-specific DNA binding - - - 0.000000000000000000001994 106.0
DTH2_k127_7837692_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 1.907e-201 634.0
DTH2_k127_7837692_30 Protein of unknown function (DUF2384) - - - 0.0000000000000001533 86.0
DTH2_k127_7837692_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 589.0
DTH2_k127_7837692_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 554.0
DTH2_k127_7837692_6 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 463.0
DTH2_k127_7837692_7 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 362.0
DTH2_k127_7837692_8 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 336.0
DTH2_k127_7837692_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 319.0
DTH2_k127_7838189_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 543.0
DTH2_k127_7838189_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 321.0
DTH2_k127_7838189_2 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 240.0
DTH2_k127_7838189_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000001371 208.0
DTH2_k127_7838189_4 Thioredoxin-like - - - 0.00000000000000000000000000000008956 130.0
DTH2_k127_7838189_5 COG0457 FOG TPR repeat - - - 0.000000000000000000000008822 115.0
DTH2_k127_7838189_6 Protein of unknown function (DUF2845) - - - 0.00000000000000001831 88.0
DTH2_k127_7838189_7 Trypsin domain PDZ domain protein - - - 0.000009589 58.0
DTH2_k127_7846601_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 537.0
DTH2_k127_7846601_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 356.0
DTH2_k127_7846601_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001625 251.0
DTH2_k127_7846601_3 - - - - 0.000000000000000000000002655 102.0
DTH2_k127_7905832_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1247.0
DTH2_k127_7905832_1 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000000009822 197.0
DTH2_k127_7905832_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000003547 188.0
DTH2_k127_7905832_3 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000002493 171.0
DTH2_k127_7905832_4 Poly-gamma-glutamate hydrolase - - - 0.00000000000000001109 86.0
DTH2_k127_7905832_6 cellulase activity K18197 - 4.2.2.23 0.00000006604 64.0
DTH2_k127_7919902_0 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000001199 127.0
DTH2_k127_7919902_1 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000001672 133.0
DTH2_k127_7919902_2 Phage integrase SAM-like domain - - - 0.0000000000000000000368 102.0
DTH2_k127_7919902_3 metallopeptidase activity K20276 - - 0.0000000001273 73.0
DTH2_k127_7919902_4 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000397 49.0
DTH2_k127_8000404_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 402.0
DTH2_k127_8000404_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 316.0
DTH2_k127_8000404_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 313.0
DTH2_k127_8000404_3 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 300.0
DTH2_k127_8000404_4 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000005535 213.0
DTH2_k127_8001040_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.978e-244 761.0
DTH2_k127_8001040_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 604.0
DTH2_k127_8001040_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 518.0
DTH2_k127_8001040_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 386.0
DTH2_k127_8001040_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 368.0
DTH2_k127_8001040_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000207 245.0
DTH2_k127_8001040_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000056 199.0
DTH2_k127_8001040_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000003632 198.0
DTH2_k127_8001040_8 Belongs to the 'phage' integrase family K04763 - - 0.00000000002939 65.0
DTH2_k127_8028929_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 4.259e-215 674.0
DTH2_k127_8028929_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.127e-206 647.0
DTH2_k127_8028929_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 354.0
DTH2_k127_8028929_11 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 349.0
DTH2_k127_8028929_12 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 333.0
DTH2_k127_8028929_13 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 328.0
DTH2_k127_8028929_14 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
DTH2_k127_8028929_15 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001064 271.0
DTH2_k127_8028929_16 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001128 271.0
DTH2_k127_8028929_17 PFAM ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000002055 217.0
DTH2_k127_8028929_18 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000004397 212.0
DTH2_k127_8028929_19 amino acid-binding ACT - - - 0.00000000000000000000000000000000000000000000000000000002373 201.0
DTH2_k127_8028929_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 2.166e-199 632.0
DTH2_k127_8028929_20 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000001641 197.0
DTH2_k127_8028929_21 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000003374 191.0
DTH2_k127_8028929_22 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000009568 151.0
DTH2_k127_8028929_23 - - - - 0.00000000000000000000000000000000000000595 150.0
DTH2_k127_8028929_24 outer membrane efflux protein - - - 0.0000000000000000000000000000000000003677 154.0
DTH2_k127_8028929_25 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000000000000001735 112.0
DTH2_k127_8028929_27 Protein of unknown function (DUF2628) - - - 0.000000000000000000002607 100.0
DTH2_k127_8028929_28 - - - - 0.00000000344 65.0
DTH2_k127_8028929_3 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 1.114e-198 639.0
DTH2_k127_8028929_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 597.0
DTH2_k127_8028929_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 480.0
DTH2_k127_8028929_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 464.0
DTH2_k127_8028929_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 429.0
DTH2_k127_8028929_8 glucose sorbosone K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 428.0
DTH2_k127_8028929_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 409.0
DTH2_k127_8054282_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1253.0
DTH2_k127_8054282_1 CARDB domain-containing protein,subtilase family protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 617.0
DTH2_k127_8054282_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000000123 152.0
DTH2_k127_8054282_12 Sulfurtransferase TusA - - - 0.000000000000000000000004647 103.0
DTH2_k127_8054282_13 PFAM flavin reductase domain protein, FMN-binding - - - 0.0002263 49.0
DTH2_k127_8054282_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 443.0
DTH2_k127_8054282_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 428.0
DTH2_k127_8054282_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 397.0
DTH2_k127_8054282_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 288.0
DTH2_k127_8054282_6 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004336 262.0
DTH2_k127_8054282_7 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000009719 196.0
DTH2_k127_8054282_8 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000001265 180.0
DTH2_k127_8054282_9 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000005626 166.0
DTH2_k127_8199223_0 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 536.0
DTH2_k127_8199223_1 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 514.0
DTH2_k127_8199223_2 - K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 443.0
DTH2_k127_8199223_3 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000003417 249.0
DTH2_k127_8199223_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000075 229.0
DTH2_k127_8199223_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000004956 208.0
DTH2_k127_8199223_6 - - - - 0.0000000000000000000000000000000000000000000000000000000204 209.0
DTH2_k127_8199223_7 rubredoxin - - - 0.00000000000000000000001051 101.0
DTH2_k127_8250550_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 8.625e-219 686.0
DTH2_k127_8250550_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 310.0
DTH2_k127_8250550_2 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000008277 136.0
DTH2_k127_82783_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001022 242.0
DTH2_k127_82783_1 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008781 242.0
DTH2_k127_82783_2 - - - - 0.00000000000000000001953 97.0
DTH2_k127_82783_3 - - - - 0.00000000008871 64.0
DTH2_k127_8481893_0 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 343.0
DTH2_k127_8481893_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 317.0
DTH2_k127_8481893_10 receptor - - - 0.00001675 50.0
DTH2_k127_8481893_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 321.0
DTH2_k127_8481893_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 289.0
DTH2_k127_8481893_4 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000002305 184.0
DTH2_k127_8481893_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000006629 181.0
DTH2_k127_8481893_6 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000000000001446 156.0
DTH2_k127_8481893_7 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000001711 128.0
DTH2_k127_8481893_8 nickel cation binding K04651,K19640 - - 0.00000000000000000000000001814 114.0
DTH2_k127_8492849_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 532.0
DTH2_k127_8492849_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 501.0
DTH2_k127_8492849_10 - - - - 0.00000000000000000000000000003991 127.0
DTH2_k127_8492849_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000308 116.0
DTH2_k127_8492849_12 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000009818 83.0
DTH2_k127_8492849_13 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000001269 82.0
DTH2_k127_8492849_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000004232 64.0
DTH2_k127_8492849_15 - - - - 0.000007562 48.0
DTH2_k127_8492849_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 475.0
DTH2_k127_8492849_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 439.0
DTH2_k127_8492849_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000005641 214.0
DTH2_k127_8492849_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000007444 208.0
DTH2_k127_8492849_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000004101 169.0
DTH2_k127_8492849_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000009297 146.0
DTH2_k127_8492849_8 AI-2E family transporter - - - 0.00000000000000000000000000000001319 141.0
DTH2_k127_8492849_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000001973 134.0
DTH2_k127_8583077_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 510.0
DTH2_k127_8583077_1 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 392.0
DTH2_k127_8583077_2 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000004568 210.0
DTH2_k127_8583077_4 TIGRFAM addiction module toxin, Txe YoeB family - - - 0.000000000000000000000000000000000001086 139.0
DTH2_k127_8583077_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000002534 109.0
DTH2_k127_8583077_6 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000003836 110.0
DTH2_k127_8583077_7 Peptidoglycan-binding domain 1 protein - - - 0.00000000000002089 76.0
DTH2_k127_8671347_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2170.0
DTH2_k127_8671347_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1992.0
DTH2_k127_8671347_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 369.0
DTH2_k127_8671347_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003629 273.0
DTH2_k127_8671347_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005979 238.0
DTH2_k127_8671347_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000002212 193.0
DTH2_k127_8671347_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002292 137.0
DTH2_k127_8671347_7 Ribosomal protein L33 K02913 - - 0.00000000000000001273 83.0
DTH2_k127_8671347_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000002508 82.0
DTH2_k127_8671347_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000004104 72.0
DTH2_k127_8720620_0 UPF0210 protein K09157 - - 2.499e-215 678.0
DTH2_k127_8720620_1 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 295.0
DTH2_k127_8720620_2 PFAM amino acid-binding ACT domain protein K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008658 246.0
DTH2_k127_8720620_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005201 245.0
DTH2_k127_8720620_4 META domain - - - 0.00000000000000000000000000000000000000000000000000000000000258 220.0
DTH2_k127_8720620_5 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000000003142 176.0
DTH2_k127_8720620_6 Nitroreductase family - - - 0.0000000000000000000000000000000002381 138.0
DTH2_k127_8720620_7 Dodecin K09165 - - 0.0000000000000000000001896 98.0
DTH2_k127_8720620_8 - - - - 0.00000000000000000004907 97.0
DTH2_k127_8863348_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1138.0
DTH2_k127_8863348_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.334e-243 766.0
DTH2_k127_8863348_2 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 499.0
DTH2_k127_8863348_3 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001083 257.0
DTH2_k127_8863348_4 membrane K00389 - - 0.000000000000000000000000000000000000000003541 159.0
DTH2_k127_8863348_5 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000004009 142.0
DTH2_k127_8863348_6 Di-haem cytochrome c peroxidase - - - 0.000000000005037 67.0
DTH2_k127_8863348_7 Predicted membrane protein (DUF2318) - - - 0.00000000005688 68.0
DTH2_k127_8863348_8 PFAM YeeE YedE family (DUF395) K07112 - - 0.00001359 48.0
DTH2_k127_8899100_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001931 294.0
DTH2_k127_8899100_1 Dimerisation domain of Zinc Transporter - - - 0.0005295 51.0
DTH2_k127_8905917_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 416.0
DTH2_k127_8905917_1 - - - - 0.00000000000000000000000000000000000000000001588 166.0
DTH2_k127_8905917_2 Histidine kinase - - - 0.00000000000000000001528 101.0
DTH2_k127_8919650_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1062.0
DTH2_k127_8919650_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 7.479e-250 783.0
DTH2_k127_8919650_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.351e-204 649.0
DTH2_k127_8919650_3 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 499.0
DTH2_k127_8919650_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 430.0
DTH2_k127_8919650_5 belongs to the CobB CobQ family K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 364.0
DTH2_k127_8919650_6 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004176 280.0
DTH2_k127_8919650_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000003901 163.0
DTH2_k127_8919650_8 Bacterial regulatory proteins, crp family K01420 - - 0.000000195 59.0
DTH2_k127_8923507_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.15e-303 938.0
DTH2_k127_8923507_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.587e-206 647.0
DTH2_k127_8923507_10 YMGG-like Gly-zipper - - - 0.000001971 57.0
DTH2_k127_8923507_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 416.0
DTH2_k127_8923507_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 370.0
DTH2_k127_8923507_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 370.0
DTH2_k127_8923507_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004789 257.0
DTH2_k127_8923507_6 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001664 241.0
DTH2_k127_8923507_7 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000006456 225.0
DTH2_k127_8923507_8 - - - - 0.000000000000000000000000000000000000000000000000000002939 198.0
DTH2_k127_8930379_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 319.0
DTH2_k127_8930379_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 300.0
DTH2_k127_8930379_2 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000759 269.0
DTH2_k127_8930379_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003191 171.0
DTH2_k127_8930379_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000004619 113.0
DTH2_k127_8930379_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000004104 72.0
DTH2_k127_8956460_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.027e-295 918.0
DTH2_k127_8956460_1 B3/4 domain K01890 - 6.1.1.20 3.662e-203 653.0
DTH2_k127_8956460_10 DNA-binding transcription factor activity K03710 - - 0.000000000000000000000000000000001038 139.0
DTH2_k127_8956460_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000005275 91.0
DTH2_k127_8956460_12 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000002303 86.0
DTH2_k127_8956460_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 607.0
DTH2_k127_8956460_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 493.0
DTH2_k127_8956460_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 466.0
DTH2_k127_8956460_5 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 465.0
DTH2_k127_8956460_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000231 242.0
DTH2_k127_8956460_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000003099 177.0
DTH2_k127_8956460_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000001274 165.0
DTH2_k127_8956460_9 Universal stress protein - - - 0.000000000000000000000000000000000000002175 152.0
DTH2_k127_8960015_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 491.0
DTH2_k127_8960015_1 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 486.0
DTH2_k127_8960015_10 Flagellar assembly protein FliH K02411 - - 0.0000000000000004074 86.0
DTH2_k127_8960015_11 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000007102 69.0
DTH2_k127_8960015_12 PFAM MgtE intracellular K02383 - - 0.00000004591 61.0
DTH2_k127_8960015_2 Bacterial regulatory protein, Fis family K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 447.0
DTH2_k127_8960015_3 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 411.0
DTH2_k127_8960015_4 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001462 279.0
DTH2_k127_8960015_5 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 256.0
DTH2_k127_8960015_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000004763 233.0
DTH2_k127_8960015_7 TIGRFAM flagellar motor stator protein MotA K02556 - - 0.0000000000000000000000000000000000000000000000000000000001324 208.0
DTH2_k127_8960015_8 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.000000000000000000000000000000000000104 147.0
DTH2_k127_8960015_9 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000008779 90.0
DTH2_k127_9137799_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1209.0
DTH2_k127_9137799_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 369.0
DTH2_k127_9137799_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 336.0
DTH2_k127_9137799_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 335.0
DTH2_k127_9137799_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000002208 215.0
DTH2_k127_9137799_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000003332 78.0
DTH2_k127_9190875_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.488e-223 712.0
DTH2_k127_9190875_1 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 357.0
DTH2_k127_9190875_10 Flagellar biosynthesis K02404 - - 0.000000000000000000000000000000000000000000001681 179.0
DTH2_k127_9190875_11 PFAM flagellar basal body rod protein K02392 - - 0.000000000000000000000000000000000000001195 156.0
DTH2_k127_9190875_12 PFAM surface presentation of antigens (SPOA) protein K02417 - - 0.0000000000000000000000000000000000009151 141.0
DTH2_k127_9190875_13 ankyrin repeats K06867 - - 0.0000000000000000000000000000000001433 149.0
DTH2_k127_9190875_14 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000003458 134.0
DTH2_k127_9190875_15 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000655 132.0
DTH2_k127_9190875_16 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000001465 96.0
DTH2_k127_9190875_17 Role in flagellar biosynthesis K02420 - - 0.0000000000000000003013 91.0
DTH2_k127_9190875_18 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000004642 87.0
DTH2_k127_9190875_19 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000003428 66.0
DTH2_k127_9190875_2 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 356.0
DTH2_k127_9190875_20 PFAM Flagellar hook-length control protein K02414 - - 0.00002236 57.0
DTH2_k127_9190875_3 Cellulose biosynthesis protein BcsQ K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 289.0
DTH2_k127_9190875_4 FliP family K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001185 254.0
DTH2_k127_9190875_5 Flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004215 256.0
DTH2_k127_9190875_6 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001933 253.0
DTH2_k127_9190875_7 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000008153 226.0
DTH2_k127_9190875_8 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000002312 218.0
DTH2_k127_9190875_9 sigma factor activity K02405,K03093 - - 0.00000000000000000000000000000000000000000000000009118 190.0
DTH2_k127_9209497_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.567e-267 837.0
DTH2_k127_9209497_1 Sigma-54 interaction domain - - - 1.404e-204 645.0
DTH2_k127_9209497_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 496.0
DTH2_k127_9209497_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 459.0
DTH2_k127_9209497_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 381.0
DTH2_k127_9209497_5 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002194 260.0
DTH2_k127_9209497_6 Universal stress protein - - - 0.0000000000000000000000000000000000002613 146.0
DTH2_k127_9209497_7 - - - - 0.0000000000000001653 81.0
DTH2_k127_92185_0 sister chromatid segregation - - - 7.191e-204 647.0
DTH2_k127_92185_1 Flavodoxin - - - 1.093e-199 628.0
DTH2_k127_92185_10 HEAT repeats - - - 0.0000000000000000000000000000000000000000000005043 186.0
DTH2_k127_92185_11 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000006375 127.0
DTH2_k127_92185_12 - - - - 0.00000000000394 66.0
DTH2_k127_92185_13 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.000000001651 66.0
DTH2_k127_92185_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 360.0
DTH2_k127_92185_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 326.0
DTH2_k127_92185_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 287.0
DTH2_k127_92185_5 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005216 264.0
DTH2_k127_92185_6 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002244 248.0
DTH2_k127_92185_7 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000001464 206.0
DTH2_k127_92185_8 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000000000000000000000000009368 177.0
DTH2_k127_92185_9 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000002898 176.0
DTH2_k127_9235011_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 5.053e-299 937.0
DTH2_k127_9235011_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 554.0
DTH2_k127_9235011_2 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000005958 181.0
DTH2_k127_9235011_3 - - - - 0.000000000000002187 78.0
DTH2_k127_9235011_4 Protein of unknown function (DUF2868) - - - 0.0000000000005067 82.0
DTH2_k127_9235011_5 Hsp70 protein - - - 0.0000001813 64.0
DTH2_k127_9328059_0 Peptidase family M28 - - - 0.0 1099.0
DTH2_k127_9328059_1 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000006835 186.0
DTH2_k127_9328059_2 Threonyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000003512 161.0
DTH2_k127_9369512_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 550.0
DTH2_k127_9369512_1 Cobalamin synthesis G N-terminal K13541 - 2.1.1.131,3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 487.0
DTH2_k127_9369512_10 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.000000000000000000000004129 112.0
DTH2_k127_9369512_12 - - - - 0.0006157 42.0
DTH2_k127_9369512_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 356.0
DTH2_k127_9369512_3 Biotin-protein ligase, N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 303.0
DTH2_k127_9369512_4 proteolysis K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009176 248.0
DTH2_k127_9369512_5 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000005877 217.0
DTH2_k127_9369512_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000839 193.0
DTH2_k127_9369512_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000001589 163.0
DTH2_k127_9369512_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000007065 143.0
DTH2_k127_9369512_9 Stringent starvation protein B K09985 - - 0.000000000000000000000000004723 118.0
DTH2_k127_9449602_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 6.186e-247 776.0
DTH2_k127_9449602_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 541.0
DTH2_k127_9449602_2 nitric oxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000006989 212.0
DTH2_k127_9449602_3 EthD domain - - - 0.0000000000000000000000000000000000000000000000000001223 186.0
DTH2_k127_9449602_4 Transposase - - - 0.0000000000000000000000000000000000000000000000001173 181.0
DTH2_k127_9449602_5 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00000000000000000000003951 105.0
DTH2_k127_9449602_6 - - - - 0.0000000000000006394 84.0
DTH2_k127_9449602_7 - - - - 0.0000000351 58.0
DTH2_k127_9449602_8 electron transfer activity K05337,K17247 - - 0.00000005062 56.0
DTH2_k127_9492364_0 Heat shock 70 kDa protein K04043 - - 3.954e-256 794.0
DTH2_k127_9492364_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.599e-240 750.0
DTH2_k127_9492364_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000002908 228.0
DTH2_k127_9492364_11 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000001695 215.0
DTH2_k127_9492364_12 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000009029 219.0
DTH2_k127_9492364_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000003805 164.0
DTH2_k127_9492364_14 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000006938 64.0
DTH2_k127_9492364_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 4.746e-234 733.0
DTH2_k127_9492364_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.076e-223 712.0
DTH2_k127_9492364_4 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 534.0
DTH2_k127_9492364_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 512.0
DTH2_k127_9492364_6 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 408.0
DTH2_k127_9492364_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 356.0
DTH2_k127_9492364_8 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 327.0
DTH2_k127_9492364_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000003947 242.0
DTH2_k127_9511047_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1135.0
DTH2_k127_9511047_1 Response regulator receiver - - - 5.896e-194 634.0
DTH2_k127_9511047_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000003987 153.0
DTH2_k127_9511047_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001413 79.0
DTH2_k127_9511047_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 503.0
DTH2_k127_9511047_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 292.0
DTH2_k127_9511047_4 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004535 261.0
DTH2_k127_9511047_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000004312 243.0
DTH2_k127_9511047_6 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000007059 232.0
DTH2_k127_9511047_7 Histidine kinase K00936,K02030 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000007576 234.0
DTH2_k127_9511047_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000007502 218.0
DTH2_k127_9511047_9 Universal stress protein family - - - 0.000000000000000000000000000000000000000000002455 169.0
DTH2_k127_9522464_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 2.191e-315 970.0
DTH2_k127_9522464_1 PFAM Acetyl-CoA hydrolase transferase K18122 - - 3.371e-281 876.0
DTH2_k127_9522464_2 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 469.0
DTH2_k127_9522464_3 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000000000000000000000007544 184.0
DTH2_k127_9654004_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.715e-196 620.0
DTH2_k127_9654004_1 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001572 276.0
DTH2_k127_968609_0 Major facilitator Superfamily K08218 - - 1.151e-254 794.0
DTH2_k127_968609_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005062 295.0
DTH2_k127_968609_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000785 246.0
DTH2_k127_968609_3 denitrification pathway - - - 0.00000000000000000000000000000000000007616 149.0
DTH2_k127_968609_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000001104 91.0
DTH2_k127_968609_5 Cytochrome c - - - 0.0000000000000006577 77.0
DTH2_k127_9919720_0 DNA polymerase Ligase (LigD) - - - 2.882e-309 966.0
DTH2_k127_9919720_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.267e-271 857.0
DTH2_k127_9919720_10 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 402.0
DTH2_k127_9919720_11 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 405.0
DTH2_k127_9919720_12 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 405.0
DTH2_k127_9919720_13 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 377.0
DTH2_k127_9919720_14 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 344.0
DTH2_k127_9919720_15 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 340.0
DTH2_k127_9919720_16 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 345.0
DTH2_k127_9919720_17 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 359.0
DTH2_k127_9919720_18 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 322.0
DTH2_k127_9919720_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
DTH2_k127_9919720_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 3.019e-263 831.0
DTH2_k127_9919720_20 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 305.0
DTH2_k127_9919720_21 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 297.0
DTH2_k127_9919720_22 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000913 285.0
DTH2_k127_9919720_23 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001342 282.0
DTH2_k127_9919720_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003915 256.0
DTH2_k127_9919720_25 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003641 241.0
DTH2_k127_9919720_26 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000003032 234.0
DTH2_k127_9919720_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000001999 232.0
DTH2_k127_9919720_28 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002075 222.0
DTH2_k127_9919720_29 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000002416 176.0
DTH2_k127_9919720_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.246e-225 711.0
DTH2_k127_9919720_30 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000005024 164.0
DTH2_k127_9919720_31 Biogenesis protein K09792 - - 0.0000000000000000000000000000000000000000007658 166.0
DTH2_k127_9919720_33 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000001313 153.0
DTH2_k127_9919720_34 Short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000008513 164.0
DTH2_k127_9919720_35 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000000001049 121.0
DTH2_k127_9919720_36 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000002026 123.0
DTH2_k127_9919720_37 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000003104 114.0
DTH2_k127_9919720_38 HDOD domain - - - 0.00000000000000001051 87.0
DTH2_k127_9919720_4 4Fe-4S binding domain - - - 1.926e-219 691.0
DTH2_k127_9919720_40 FixH - - - 0.0000000000000004296 88.0
DTH2_k127_9919720_41 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.000000000000002198 79.0
DTH2_k127_9919720_42 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000000000000003534 80.0
DTH2_k127_9919720_43 protein homooligomerization - - - 0.0000000000007489 78.0
DTH2_k127_9919720_44 Histidine kinase - - - 0.0000000000009206 73.0
DTH2_k127_9919720_45 Transglycosylase SLT domain - - - 0.0000000003192 69.0
DTH2_k127_9919720_46 deoxyhypusine monooxygenase activity - - - 0.0000000008143 71.0
DTH2_k127_9919720_47 Cbb3-type cytochrome oxidase component FixQ - - - 0.000002772 51.0
DTH2_k127_9919720_48 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00001427 48.0
DTH2_k127_9919720_49 FixH - - - 0.00005921 54.0
DTH2_k127_9919720_5 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 546.0
DTH2_k127_9919720_6 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 536.0
DTH2_k127_9919720_7 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 502.0
DTH2_k127_9919720_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 460.0
DTH2_k127_9919720_9 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 437.0