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Overview

ID MAG00793
Name DTH2_bin.8
Sample SMP0023
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family UBA6910
Genus UBA6910
Species
Assembly information
Completeness (%) 89.51
Contamination (%) 3.82
GC content (%) 70.0
N50 (bp) 7,764
Genome size (bp) 2,829,633

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2892

Gene name Description KEGG GOs EC E-value Score Sequence
DTH2_k127_10021014_0 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 539.0
DTH2_k127_10021014_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 434.0
DTH2_k127_10021014_2 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001995 278.0
DTH2_k127_10021014_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001755 236.0
DTH2_k127_10021014_4 HPP family K07168 - - 0.00000000000000000000000000000000000000000000000003648 182.0
DTH2_k127_10021219_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 554.0
DTH2_k127_10021219_1 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
DTH2_k127_10021219_2 PFAM periplasmic binding protein K02016 - - 0.00000000006204 63.0
DTH2_k127_10053035_0 Enoyl-(Acyl carrier protein) reductase K16066 - 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 289.0
DTH2_k127_10053035_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 290.0
DTH2_k127_10053035_2 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000001342 174.0
DTH2_k127_1018463_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.049e-267 829.0
DTH2_k127_1018463_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 6.394e-207 651.0
DTH2_k127_1018463_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.004e-195 612.0
DTH2_k127_1018463_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 527.0
DTH2_k127_1018463_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 391.0
DTH2_k127_1018463_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
DTH2_k127_1038027_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 1.862e-200 627.0
DTH2_k127_1038027_1 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 322.0
DTH2_k127_1038027_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000005198 248.0
DTH2_k127_1038027_3 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000003127 164.0
DTH2_k127_1038027_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000008188 135.0
DTH2_k127_1038027_5 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0000000000000000116 84.0
DTH2_k127_1046383_0 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 494.0
DTH2_k127_1046383_1 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 391.0
DTH2_k127_1046383_2 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 281.0
DTH2_k127_1046383_3 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004505 273.0
DTH2_k127_1094087_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1363.0
DTH2_k127_1094087_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 572.0
DTH2_k127_1094087_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 554.0
DTH2_k127_1094087_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 556.0
DTH2_k127_1094087_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 463.0
DTH2_k127_1094087_5 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 372.0
DTH2_k127_1094087_6 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 355.0
DTH2_k127_1094087_7 Protein conserved in bacteria - - - 0.0000000000000912 84.0
DTH2_k127_1095380_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 569.0
DTH2_k127_1095380_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 519.0
DTH2_k127_1095380_2 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 273.0
DTH2_k127_1095380_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
DTH2_k127_1095380_4 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
DTH2_k127_1095380_5 Protein of unknown function (DUF2788) - - - 0.000000000000000000000006778 102.0
DTH2_k127_1113899_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.42e-208 655.0
DTH2_k127_1113899_1 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 453.0
DTH2_k127_1118179_0 FAD linked oxidases, C-terminal domain K18930 - - 1.266e-266 831.0
DTH2_k127_1118179_1 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 340.0
DTH2_k127_1118179_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 312.0
DTH2_k127_1118179_3 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000000000000000000000001184 247.0
DTH2_k127_1118179_4 nitrogen regulatory protein PII - - - 0.0000000000000000724 81.0
DTH2_k127_1130637_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 412.0
DTH2_k127_1130637_1 SurA N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006542 286.0
DTH2_k127_1130637_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
DTH2_k127_1130637_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000002878 196.0
DTH2_k127_1190346_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1007.0
DTH2_k127_1190346_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.448e-281 871.0
DTH2_k127_1190346_10 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000277 276.0
DTH2_k127_1190346_11 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000007358 219.0
DTH2_k127_1190346_12 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000008627 176.0
DTH2_k127_1190346_13 Protein of unknown function (DUF3106) - - - 0.00000000000000000000007904 109.0
DTH2_k127_1190346_14 Protein of unknown function (DUF2905) - - - 0.000000000000000000000099 99.0
DTH2_k127_1190346_16 Protein of unknown function (DUF3619) - - - 0.000000000008372 72.0
DTH2_k127_1190346_17 - - - - 0.0000003711 57.0
DTH2_k127_1190346_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.422e-265 835.0
DTH2_k127_1190346_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 561.0
DTH2_k127_1190346_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 382.0
DTH2_k127_1190346_5 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 384.0
DTH2_k127_1190346_6 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 297.0
DTH2_k127_1190346_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
DTH2_k127_1190346_8 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 267.0
DTH2_k127_1190346_9 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002873 265.0
DTH2_k127_1200317_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 451.0
DTH2_k127_1200317_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 420.0
DTH2_k127_1200317_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 331.0
DTH2_k127_1200317_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 317.0
DTH2_k127_1200317_5 dTDP-6-deoxy-3,4-keto-hexulose isomerase - - - 0.000000000000000000000000000000000000000404 161.0
DTH2_k127_1200317_6 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.00000000000000000000002645 100.0
DTH2_k127_1200317_7 membrane - - - 0.00006316 54.0
DTH2_k127_1226701_0 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 293.0
DTH2_k127_1226701_1 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000008012 162.0
DTH2_k127_1237769_0 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 305.0
DTH2_k127_1237769_1 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000007419 175.0
DTH2_k127_1297476_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 594.0
DTH2_k127_1297476_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 506.0
DTH2_k127_1297476_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000005433 117.0
DTH2_k127_1297982_0 PQQ-like domain K00114 - 1.1.2.8 9.466e-318 983.0
DTH2_k127_1297982_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 374.0
DTH2_k127_1297982_2 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 328.0
DTH2_k127_1297982_3 Sulphur oxidation protein SoxZ K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 298.0
DTH2_k127_1297982_4 helix_turn_helix, Lux Regulon K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005841 266.0
DTH2_k127_1297982_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001292 247.0
DTH2_k127_1297982_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000005743 141.0
DTH2_k127_1297982_7 - - - - 0.00000000000000001038 97.0
DTH2_k127_131221_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.105e-251 782.0
DTH2_k127_131221_1 Belongs to the GARS family K01945 - 6.3.4.13 1.86e-204 644.0
DTH2_k127_131221_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 543.0
DTH2_k127_131221_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 529.0
DTH2_k127_131221_4 Selenocysteine lyase K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 384.0
DTH2_k127_131221_5 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003412 247.0
DTH2_k127_131221_6 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000004338 206.0
DTH2_k127_131221_7 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000001586 117.0
DTH2_k127_131221_8 - - - - 0.0003851 45.0
DTH2_k127_1323095_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 8.164e-270 839.0
DTH2_k127_1323095_1 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
DTH2_k127_1323095_2 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000002803 71.0
DTH2_k127_1323095_3 - - - - 0.0001411 45.0
DTH2_k127_1343404_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 308.0
DTH2_k127_1343404_1 PIN domain - - - 0.000000000000000000000000000000000005473 145.0
DTH2_k127_136178_0 Protein of unknown function (DUF1254) - - - 2.962e-239 747.0
DTH2_k127_136178_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.822e-234 732.0
DTH2_k127_136178_10 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000001232 50.0
DTH2_k127_136178_11 - - - - 0.000002774 52.0
DTH2_k127_136178_2 SAF - - - 3.608e-212 670.0
DTH2_k127_136178_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 456.0
DTH2_k127_136178_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 311.0
DTH2_k127_136178_5 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006431 253.0
DTH2_k127_136178_6 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000002375 111.0
DTH2_k127_136178_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000001108 79.0
DTH2_k127_136178_8 PFAM cytochrome c, class I K08738 - - 0.00000000007293 70.0
DTH2_k127_136178_9 PFAM cytochrome c, class I K08738 - - 0.0000000004579 68.0
DTH2_k127_1419050_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 462.0
DTH2_k127_1419050_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 317.0
DTH2_k127_1419050_2 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 251.0
DTH2_k127_1419050_3 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000972 80.0
DTH2_k127_1422167_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002165 225.0
DTH2_k127_1422167_1 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000004573 190.0
DTH2_k127_1422167_2 Protein of unknown function (DUF3301) - - - 0.0000000000000000009257 99.0
DTH2_k127_1463551_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 590.0
DTH2_k127_1463551_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 440.0
DTH2_k127_1463551_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
DTH2_k127_1463551_3 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 317.0
DTH2_k127_1515366_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.17e-207 647.0
DTH2_k127_1515366_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 432.0
DTH2_k127_1515366_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 405.0
DTH2_k127_1515366_3 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 360.0
DTH2_k127_1515366_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000008326 203.0
DTH2_k127_1515366_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000002549 199.0
DTH2_k127_1515366_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000309 138.0
DTH2_k127_1515366_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000009552 138.0
DTH2_k127_1520636_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 319.0
DTH2_k127_1520636_1 Baseplate J-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
DTH2_k127_1520636_2 Protein conserved in bacteria K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000001338 232.0
DTH2_k127_1520636_3 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000001539 143.0
DTH2_k127_1520636_4 Phage late control gene D protein (GPD) - - - 0.0000000000000000000005913 97.0
DTH2_k127_1547754_0 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.0000000000000000000000000001757 125.0
DTH2_k127_1547754_1 HPP family K07168 - - 0.00000000000000000006103 93.0
DTH2_k127_1547754_2 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000001162 91.0
DTH2_k127_1547754_3 - - - - 0.0000000001028 72.0
DTH2_k127_1553136_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 585.0
DTH2_k127_1553136_1 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
DTH2_k127_1553136_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00001323 47.0
DTH2_k127_1562414_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 457.0
DTH2_k127_1562414_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 378.0
DTH2_k127_1562414_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 350.0
DTH2_k127_1562414_3 Methyl-transferase K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 294.0
DTH2_k127_1562414_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000002954 254.0
DTH2_k127_1562414_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000001748 249.0
DTH2_k127_1562414_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000001354 203.0
DTH2_k127_1562414_7 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000005582 196.0
DTH2_k127_159883_0 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 541.0
DTH2_k127_159883_1 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 464.0
DTH2_k127_159883_2 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 311.0
DTH2_k127_159883_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 295.0
DTH2_k127_159883_4 FMN_bind K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000005272 249.0
DTH2_k127_159883_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000001621 146.0
DTH2_k127_1603543_0 Belongs to the malate synthase family K01638 - 2.3.3.9 1.608e-270 841.0
DTH2_k127_1603543_1 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 565.0
DTH2_k127_1603543_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
DTH2_k127_1603543_3 (ABC) transporter K05685,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
DTH2_k127_1603543_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000004475 73.0
DTH2_k127_16144_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 8.211e-212 667.0
DTH2_k127_16144_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000006859 217.0
DTH2_k127_16144_2 cell wall formation K00075 - 1.3.1.98 0.0000000000006958 70.0
DTH2_k127_1623705_0 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 477.0
DTH2_k127_1623705_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000003029 225.0
DTH2_k127_1623705_2 Sensory box protein response regulator - - - 0.00000000000000000000000000002312 119.0
DTH2_k127_1623705_3 - - - - 0.000009878 53.0
DTH2_k127_1652715_0 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 403.0
DTH2_k127_1652715_1 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 391.0
DTH2_k127_1659280_0 Glucose / Sorbosone dehydrogenase - - - 2.371e-234 730.0
DTH2_k127_1659280_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.112e-215 684.0
DTH2_k127_1659280_2 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 372.0
DTH2_k127_1659280_3 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001613 265.0
DTH2_k127_1659280_4 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003253 231.0
DTH2_k127_1659280_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
DTH2_k127_1659280_6 Cytochrome c - - - 0.00000000000000000000008307 109.0
DTH2_k127_1659280_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000001074 84.0
DTH2_k127_1669077_0 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000003984 206.0
DTH2_k127_1669077_1 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000002515 170.0
DTH2_k127_1669077_2 Type II secretory pathway pseudopilin - - - 0.0000000000000000000000000000000000000000000876 171.0
DTH2_k127_1669077_3 Secretin and TonB N terminus short domain K02453 - - 0.000000000000001863 82.0
DTH2_k127_168705_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1168.0
DTH2_k127_168705_1 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.583e-301 937.0
DTH2_k127_168705_10 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000000000008028 167.0
DTH2_k127_168705_11 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000004707 172.0
DTH2_k127_168705_12 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.0000000000000000000000000000000000000000005108 160.0
DTH2_k127_168705_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000004355 70.0
DTH2_k127_168705_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 2.19e-293 904.0
DTH2_k127_168705_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 556.0
DTH2_k127_168705_4 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 461.0
DTH2_k127_168705_5 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 399.0
DTH2_k127_168705_6 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 303.0
DTH2_k127_168705_7 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 287.0
DTH2_k127_168705_8 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001047 267.0
DTH2_k127_168705_9 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000001057 237.0
DTH2_k127_1728741_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 523.0
DTH2_k127_1728741_1 Small MutS-related domain - - - 0.00000000000000000000000000000000000000000000000001548 186.0
DTH2_k127_1728741_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000001444 119.0
DTH2_k127_1728741_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000005224 101.0
DTH2_k127_1751057_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.518e-221 698.0
DTH2_k127_1751057_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 326.0
DTH2_k127_1757271_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 367.0
DTH2_k127_1757271_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 306.0
DTH2_k127_1757271_2 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.000000000000000000000000000000000000000000000396 179.0
DTH2_k127_1757271_4 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.00005434 54.0
DTH2_k127_1798787_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1664.0
DTH2_k127_1798787_1 4Fe-4S dicluster domain - - - 9.006e-233 745.0
DTH2_k127_1798787_2 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 395.0
DTH2_k127_1798787_3 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 349.0
DTH2_k127_1798787_4 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000002387 174.0
DTH2_k127_1798787_5 Protein of unknown function (DUF3306) - - - 0.000000000000000000000008838 105.0
DTH2_k127_1798787_6 - - - - 0.00000000000000002673 85.0
DTH2_k127_1798787_7 - - - - 0.00000000003358 73.0
DTH2_k127_180457_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1065.0
DTH2_k127_180457_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 5.973e-315 982.0
DTH2_k127_180457_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000009705 185.0
DTH2_k127_180457_11 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000002872 171.0
DTH2_k127_180457_12 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000001446 134.0
DTH2_k127_180457_13 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000005569 128.0
DTH2_k127_180457_14 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000002592 127.0
DTH2_k127_180457_15 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000006835 94.0
DTH2_k127_180457_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 4.077e-288 895.0
DTH2_k127_180457_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.52e-282 883.0
DTH2_k127_180457_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 567.0
DTH2_k127_180457_5 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 502.0
DTH2_k127_180457_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 477.0
DTH2_k127_180457_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
DTH2_k127_180457_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000009482 229.0
DTH2_k127_180457_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000006447 197.0
DTH2_k127_1811657_0 twitching motility protein K02670 - - 6.135e-201 630.0
DTH2_k127_1811657_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 603.0
DTH2_k127_1811657_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000002067 186.0
DTH2_k127_1811657_3 THUMP K07444 - - 0.000000000000000000000000000000000000000916 150.0
DTH2_k127_1814888_0 von Willebrand factor (vWF) type A domain K16259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000246 254.0
DTH2_k127_1814888_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
DTH2_k127_1814888_2 Pterin 4 alpha carbinolamine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000002629 219.0
DTH2_k127_1814888_3 - - - - 0.000000000000000000000006174 109.0
DTH2_k127_1816171_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 557.0
DTH2_k127_1816171_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 287.0
DTH2_k127_1816171_2 PFAM PemK family protein K07171 - - 0.000000000000000000000000000000000000000004182 160.0
DTH2_k127_1816171_3 - - - - 0.0000000000000000000000000000000000008742 141.0
DTH2_k127_1816171_4 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000002506 129.0
DTH2_k127_1816171_5 Transcriptional regulator antitoxin, MazE K07172 - - 0.00000000000002891 75.0
DTH2_k127_1830620_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.367e-249 786.0
DTH2_k127_1830620_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 589.0
DTH2_k127_1830620_10 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000003325 191.0
DTH2_k127_1830620_11 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000001406 191.0
DTH2_k127_1830620_12 protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000001447 169.0
DTH2_k127_1830620_13 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000004322 149.0
DTH2_k127_1830620_14 NusG domain II - - - 0.000000000000004194 79.0
DTH2_k127_1830620_15 Pfam O-Antigen Polymerase - - - 0.000000000001409 81.0
DTH2_k127_1830620_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 421.0
DTH2_k127_1830620_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 412.0
DTH2_k127_1830620_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 389.0
DTH2_k127_1830620_5 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 392.0
DTH2_k127_1830620_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 317.0
DTH2_k127_1830620_7 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
DTH2_k127_1830620_8 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000001136 218.0
DTH2_k127_1830620_9 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000002354 212.0
DTH2_k127_1873490_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 499.0
DTH2_k127_1873490_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 498.0
DTH2_k127_1873490_2 1-deoxy-D-xylulose-5-phosphate synthase K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 466.0
DTH2_k127_1873490_3 TIR domain - - - 0.00000000000000000000000000000000000000001352 160.0
DTH2_k127_1873490_4 NnrU protein - - - 0.0000000000000000000000000000000000000002069 155.0
DTH2_k127_1877632_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 509.0
DTH2_k127_1877632_1 Glucose sorbosone K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 508.0
DTH2_k127_1877632_10 Tetratricopeptide repeat - - - 0.0000000000000000000000119 108.0
DTH2_k127_1877632_11 - - - - 0.0000000000000000002656 98.0
DTH2_k127_1877632_12 histone deacetylase - - - 0.00000000000002278 76.0
DTH2_k127_1877632_2 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 399.0
DTH2_k127_1877632_3 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 360.0
DTH2_k127_1877632_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 352.0
DTH2_k127_1877632_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 320.0
DTH2_k127_1877632_6 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 319.0
DTH2_k127_1877632_7 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000002508 239.0
DTH2_k127_1877632_8 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000597 241.0
DTH2_k127_1879095_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1254.0
DTH2_k127_1879095_1 extracellular solute-binding protein - - - 0.0 1028.0
DTH2_k127_1879095_10 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 416.0
DTH2_k127_1879095_11 TIGRFAM squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 365.0
DTH2_k127_1879095_12 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 353.0
DTH2_k127_1879095_13 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000001564 124.0
DTH2_k127_1879095_14 - - - - 0.00000000004237 65.0
DTH2_k127_1879095_15 Short-chain dehydrogenase reductase SDR - - - 0.00001884 48.0
DTH2_k127_1879095_16 - - - - 0.0004922 52.0
DTH2_k127_1879095_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 7.022e-270 869.0
DTH2_k127_1879095_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.9e-221 690.0
DTH2_k127_1879095_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 8.468e-196 622.0
DTH2_k127_1879095_5 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 598.0
DTH2_k127_1879095_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 552.0
DTH2_k127_1879095_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 520.0
DTH2_k127_1879095_8 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 455.0
DTH2_k127_1879095_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 427.0
DTH2_k127_1913306_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1378.0
DTH2_k127_1913306_1 CoA-binding domain protein K09181 - - 0.0 1093.0
DTH2_k127_1913306_10 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 309.0
DTH2_k127_1913306_11 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
DTH2_k127_1913306_12 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000111 245.0
DTH2_k127_1913306_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000001877 237.0
DTH2_k127_1913306_14 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000009987 142.0
DTH2_k127_1913306_15 - - - - 0.00000000000000000003934 94.0
DTH2_k127_1913306_16 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000002378 94.0
DTH2_k127_1913306_17 Signal Transduction Histidine Kinase - - - 0.0000000000009468 82.0
DTH2_k127_1913306_2 homoserine dehydrogenase K00003 - 1.1.1.3 7.614e-229 714.0
DTH2_k127_1913306_3 Threonine synthase K01733 - 4.2.3.1 5.516e-224 702.0
DTH2_k127_1913306_4 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 3.103e-221 694.0
DTH2_k127_1913306_5 Aminotransferase class I and II K14261 - - 2.565e-209 655.0
DTH2_k127_1913306_6 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 473.0
DTH2_k127_1913306_7 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 424.0
DTH2_k127_1913306_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 385.0
DTH2_k127_1913306_9 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 355.0
DTH2_k127_1927950_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 368.0
DTH2_k127_1927950_1 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
DTH2_k127_1927950_2 ABC-2 family transporter protein K01992 - - 0.0000000000000003509 81.0
DTH2_k127_1934977_0 AMP-binding enzyme C-terminal domain K00666 - - 2.623e-282 874.0
DTH2_k127_1934977_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.633e-226 707.0
DTH2_k127_1934977_2 ABC transporter K01999 - - 4.343e-198 624.0
DTH2_k127_1934977_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 493.0
DTH2_k127_1934977_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 415.0
DTH2_k127_1934977_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 380.0
DTH2_k127_1934977_6 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000006571 188.0
DTH2_k127_1934977_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000002277 135.0
DTH2_k127_1934977_8 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000039 113.0
DTH2_k127_1934977_9 - - - - 0.000000000000000007393 100.0
DTH2_k127_1961423_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.787e-206 649.0
DTH2_k127_1961423_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 506.0
DTH2_k127_1961423_2 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 419.0
DTH2_k127_1961423_3 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 388.0
DTH2_k127_1961423_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 321.0
DTH2_k127_1961423_5 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000005137 229.0
DTH2_k127_1961423_6 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000001241 194.0
DTH2_k127_1961423_7 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000001118 180.0
DTH2_k127_1961423_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000002383 164.0
DTH2_k127_1961423_9 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000001403 136.0
DTH2_k127_1994466_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.427e-234 747.0
DTH2_k127_1994466_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000004274 209.0
DTH2_k127_1994466_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000001206 203.0
DTH2_k127_1996728_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.83e-253 784.0
DTH2_k127_1996728_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.101e-235 744.0
DTH2_k127_1996728_2 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 5.413e-231 720.0
DTH2_k127_1996728_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 347.0
DTH2_k127_1996728_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
DTH2_k127_1996728_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
DTH2_k127_1996728_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001028 242.0
DTH2_k127_1996728_7 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000002732 129.0
DTH2_k127_1998170_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1052.0
DTH2_k127_1998170_1 Thermostable hemolysin - - - 0.000000000000000000000000000000000000000000002597 172.0
DTH2_k127_1998170_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000009103 163.0
DTH2_k127_1998170_3 CHAD - - - 0.000000000000000556 81.0
DTH2_k127_2035806_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 510.0
DTH2_k127_2035806_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000017 230.0
DTH2_k127_2035806_2 YMGG-like Gly-zipper - - - 0.0000000000000002993 83.0
DTH2_k127_2053336_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 524.0
DTH2_k127_2053336_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 531.0
DTH2_k127_2053336_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 482.0
DTH2_k127_2053336_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 447.0
DTH2_k127_2053336_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 358.0
DTH2_k127_2053336_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000002593 205.0
DTH2_k127_2053336_6 PIN domain K07065 - - 0.0000000000000000000000000000000001078 137.0
DTH2_k127_2053336_7 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000009855 91.0
DTH2_k127_2053336_8 Glycosyl transferase family 4 - - - 0.00000008369 57.0
DTH2_k127_206448_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 429.0
DTH2_k127_206448_2 PFAM Nucleotidyltransferase domain K07075 - - 0.000000000000000000005552 94.0
DTH2_k127_2067040_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1e-323 1006.0
DTH2_k127_2067040_1 AAA ATPase central domain protein K07478 - - 7.741e-221 691.0
DTH2_k127_2067040_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.254e-209 657.0
DTH2_k127_2067040_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 473.0
DTH2_k127_2067040_4 Helix-turn-helix type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 417.0
DTH2_k127_2067040_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
DTH2_k127_2067040_6 Transcriptional regulator crp fnr family K10914 - - 0.00000000000000000000000000000000001487 139.0
DTH2_k127_2067040_7 Virulence protein RhuM family - - - 0.000000000001979 77.0
DTH2_k127_2067040_8 receptor - - - 0.00001405 51.0
DTH2_k127_2068334_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 345.0
DTH2_k127_2068334_1 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000002252 130.0
DTH2_k127_2127547_0 Belongs to the GPI family K01810 - 5.3.1.9 2.04e-266 828.0
DTH2_k127_2127547_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 445.0
DTH2_k127_2127547_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
DTH2_k127_2127547_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000003167 92.0
DTH2_k127_2137809_0 Peptidase M1 membrane alanine aminopeptidase - - - 2.789e-221 707.0
DTH2_k127_2137809_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 374.0
DTH2_k127_2149461_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 460.0
DTH2_k127_2149461_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000003917 234.0
DTH2_k127_2164442_0 Protein of unknown function (DUF3141) - - - 0.0 1032.0
DTH2_k127_2164442_1 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 3.895e-241 759.0
DTH2_k127_2164442_10 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000002505 141.0
DTH2_k127_2164442_11 - - - - 0.00000000000000000000000003099 110.0
DTH2_k127_2164442_12 - - - - 0.00000000000000002774 87.0
DTH2_k127_2164442_13 - - - - 0.000000008634 58.0
DTH2_k127_2164442_14 - - - - 0.00000001375 63.0
DTH2_k127_2164442_15 - - - - 0.00001554 50.0
DTH2_k127_2164442_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 575.0
DTH2_k127_2164442_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 549.0
DTH2_k127_2164442_4 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 460.0
DTH2_k127_2164442_5 phosphate K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 459.0
DTH2_k127_2164442_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 437.0
DTH2_k127_2164442_7 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002601 205.0
DTH2_k127_2164442_8 lipid catabolic process - - - 0.0000000000000000000000000000000000000000000005543 184.0
DTH2_k127_2164442_9 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000004447 149.0
DTH2_k127_2168839_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1244.0
DTH2_k127_2168839_1 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1149.0
DTH2_k127_2168839_10 MerR HTH family regulatory protein K18997 - - 0.00000000004978 68.0
DTH2_k127_2168839_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000001097 64.0
DTH2_k127_2168839_12 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000004055 62.0
DTH2_k127_2168839_13 DNA recombination-mediator protein A K04096 - - 0.00000004283 54.0
DTH2_k127_2168839_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 5.998e-197 623.0
DTH2_k127_2168839_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
DTH2_k127_2168839_4 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 432.0
DTH2_k127_2168839_5 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 370.0
DTH2_k127_2168839_6 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000002813 232.0
DTH2_k127_2168839_7 Belongs to the SfsA family K01892,K06206 - 6.1.1.21 0.00000000000000000000000000000007329 129.0
DTH2_k127_2168839_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000009513 113.0
DTH2_k127_2168839_9 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000009732 74.0
DTH2_k127_220188_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 6.614e-250 784.0
DTH2_k127_220188_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 1.627e-203 639.0
DTH2_k127_220188_10 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000001033 183.0
DTH2_k127_220188_11 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000003956 136.0
DTH2_k127_220188_12 - - - - 0.00000000000000000000000000000001227 132.0
DTH2_k127_220188_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.062e-196 617.0
DTH2_k127_220188_3 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 544.0
DTH2_k127_220188_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 544.0
DTH2_k127_220188_5 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 432.0
DTH2_k127_220188_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 426.0
DTH2_k127_220188_7 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 423.0
DTH2_k127_220188_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 314.0
DTH2_k127_220188_9 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 303.0
DTH2_k127_2228981_0 Cytochrome b(N-terminal)/b6/petB - - - 1.96e-253 797.0
DTH2_k127_2228981_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 320.0
DTH2_k127_2228981_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 288.0
DTH2_k127_2228981_3 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004474 260.0
DTH2_k127_2228981_4 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001806 262.0
DTH2_k127_2228981_5 - - - - 0.0000000000000000000000000000000000000003371 155.0
DTH2_k127_2239705_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.077e-224 699.0
DTH2_k127_2239705_1 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 535.0
DTH2_k127_2239705_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 365.0
DTH2_k127_2239705_3 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 355.0
DTH2_k127_2239705_4 SecretomeP prediction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 333.0
DTH2_k127_2239705_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000107 285.0
DTH2_k127_2239705_6 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 283.0
DTH2_k127_2239705_7 stringent starvation protein B K03600 - - 0.00000000000000000000000000000002301 126.0
DTH2_k127_2239705_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000001501 124.0
DTH2_k127_2239705_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000001929 56.0
DTH2_k127_2365143_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.858e-217 682.0
DTH2_k127_2365143_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 371.0
DTH2_k127_2365143_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000001027 202.0
DTH2_k127_2365143_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000007561 197.0
DTH2_k127_2365143_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000004976 132.0
DTH2_k127_2365143_5 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000001099 108.0
DTH2_k127_237644_0 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 395.0
DTH2_k127_237644_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000008477 203.0
DTH2_k127_2418882_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.322e-286 893.0
DTH2_k127_2418882_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 406.0
DTH2_k127_2418882_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 349.0
DTH2_k127_2418882_3 4Fe-4S ferredoxin K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 321.0
DTH2_k127_2418882_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000002998 263.0
DTH2_k127_2418882_5 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
DTH2_k127_2418882_6 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001169 248.0
DTH2_k127_2418882_7 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002583 224.0
DTH2_k127_248535_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
DTH2_k127_248535_1 - - - - 0.0000000000000000000000000000002943 137.0
DTH2_k127_2487503_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1641.0
DTH2_k127_2487503_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 549.0
DTH2_k127_2487503_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000002059 171.0
DTH2_k127_2503191_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 423.0
DTH2_k127_2503191_1 - - - - 0.000000000000000000000000001286 116.0
DTH2_k127_2503191_2 - - - - 0.0000000000000001463 80.0
DTH2_k127_2552804_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
DTH2_k127_2552804_1 Signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 418.0
DTH2_k127_2552804_2 PFAM response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000000002967 230.0
DTH2_k127_2552804_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000007424 117.0
DTH2_k127_2582049_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.216e-206 652.0
DTH2_k127_2582049_1 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 502.0
DTH2_k127_2582049_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 446.0
DTH2_k127_2582049_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.00000000000000000000000000000000000002224 145.0
DTH2_k127_258547_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 350.0
DTH2_k127_258547_1 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000000000000003436 237.0
DTH2_k127_258547_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000002059 216.0
DTH2_k127_258547_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000002042 160.0
DTH2_k127_258547_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000538 126.0
DTH2_k127_258547_5 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000003472 93.0
DTH2_k127_260020_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 395.0
DTH2_k127_260020_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000005102 231.0
DTH2_k127_260020_2 - - - - 0.00000000000000000000000000000000005667 147.0
DTH2_k127_260020_3 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000000001722 135.0
DTH2_k127_260020_4 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000001301 126.0
DTH2_k127_260020_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000009219 80.0
DTH2_k127_260020_6 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.0002425 44.0
DTH2_k127_260270_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 9.927e-209 655.0
DTH2_k127_260270_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 604.0
DTH2_k127_260270_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 533.0
DTH2_k127_260270_3 Histidine kinase K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 482.0
DTH2_k127_260270_4 response regulator receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 325.0
DTH2_k127_260270_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005298 298.0
DTH2_k127_260270_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000008286 176.0
DTH2_k127_260270_7 - - - - 0.0000000001664 63.0
DTH2_k127_2607539_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 1.62e-224 706.0
DTH2_k127_2607539_1 Trypsin K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 541.0
DTH2_k127_2607539_2 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004148 295.0
DTH2_k127_2607539_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
DTH2_k127_2607539_4 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000833 249.0
DTH2_k127_2607539_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000005514 171.0
DTH2_k127_2607539_6 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000001169 131.0
DTH2_k127_2607539_7 Protein of unknown function (DUF3460) - - - 0.0000000000003698 73.0
DTH2_k127_260942_0 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 436.0
DTH2_k127_260942_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 406.0
DTH2_k127_260942_2 TPM domain K08988 - - 0.000000000000000000000000000000000000000000000007397 174.0
DTH2_k127_2623622_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1911.0
DTH2_k127_2623622_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1370.0
DTH2_k127_2623622_10 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000002221 113.0
DTH2_k127_2623622_2 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 6.315e-233 726.0
DTH2_k127_2623622_3 TRAP transporter solute receptor TAXI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 455.0
DTH2_k127_2623622_4 Protein of unknown function (DUF2863) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 440.0
DTH2_k127_2623622_5 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001295 263.0
DTH2_k127_2623622_6 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000054 259.0
DTH2_k127_2623622_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
DTH2_k127_2623622_8 photosynthesis - - - 0.0000000000000000000000000000000000000000000000001326 181.0
DTH2_k127_2623622_9 YCII-related domain K09780 - - 0.00000000000000000000000000000000000000000008059 171.0
DTH2_k127_2641760_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000269 207.0
DTH2_k127_2641760_1 - - - - 0.00000000000000000000000000000000000000000000000000000001015 208.0
DTH2_k127_2641760_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000003063 203.0
DTH2_k127_2660576_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 591.0
DTH2_k127_2660576_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 434.0
DTH2_k127_2660576_2 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 352.0
DTH2_k127_2660576_3 - - - - 0.000000000000000000000006445 104.0
DTH2_k127_2660576_4 Glycine-zipper domain - - - 0.0000000000000009428 78.0
DTH2_k127_2673250_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1258.0
DTH2_k127_2673250_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.96e-208 668.0
DTH2_k127_2673250_2 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 418.0
DTH2_k127_2673250_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 396.0
DTH2_k127_2673250_4 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 318.0
DTH2_k127_2673250_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 296.0
DTH2_k127_2673250_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
DTH2_k127_2673250_7 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000182 139.0
DTH2_k127_2689167_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 306.0
DTH2_k127_2689167_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000236 251.0
DTH2_k127_2689167_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000004704 224.0
DTH2_k127_2689167_3 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000002057 169.0
DTH2_k127_2689167_4 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000001728 147.0
DTH2_k127_2689167_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000003658 113.0
DTH2_k127_2692567_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.704e-250 786.0
DTH2_k127_2692567_1 PFAM ABC-1 domain protein K03688 - - 2.384e-248 777.0
DTH2_k127_2692567_10 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000002222 184.0
DTH2_k127_2692567_11 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000006517 156.0
DTH2_k127_2692567_2 Binding-protein-dependent transport system inner membrane component K02011 - - 1.441e-225 711.0
DTH2_k127_2692567_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 550.0
DTH2_k127_2692567_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
DTH2_k127_2692567_5 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 370.0
DTH2_k127_2692567_6 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 351.0
DTH2_k127_2692567_7 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 319.0
DTH2_k127_2692567_8 - - - - 0.000000000000000000000000000000000000000000000000000005079 197.0
DTH2_k127_2692567_9 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000001592 182.0
DTH2_k127_269600_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1013.0
DTH2_k127_269600_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002403 263.0
DTH2_k127_269600_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004798 244.0
DTH2_k127_269600_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000006179 111.0
DTH2_k127_269600_4 - - - - 0.0000000001368 67.0
DTH2_k127_2696808_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1004.0
DTH2_k127_2696808_1 dihydroorotase K01465 - 3.5.2.3 2.712e-210 660.0
DTH2_k127_2696808_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 521.0
DTH2_k127_2696808_3 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000001255 218.0
DTH2_k127_2696808_4 Pfam Glutaredoxin - - - 0.000000000000000000000000000001461 141.0
DTH2_k127_2696808_5 domain protein K13276 GO:0005575,GO:0005576 - 0.0000000000000006586 91.0
DTH2_k127_2696808_6 - - - - 0.0000000005207 72.0
DTH2_k127_2707482_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 451.0
DTH2_k127_2707482_1 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 317.0
DTH2_k127_2707482_2 PFAM Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000005387 104.0
DTH2_k127_2709586_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.249e-290 897.0
DTH2_k127_2709586_1 Sodium:solute symporter family - - - 6.102e-284 889.0
DTH2_k127_2709586_2 SMART CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 616.0
DTH2_k127_2709586_3 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 482.0
DTH2_k127_2709586_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000007351 169.0
DTH2_k127_2709586_5 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000005619 157.0
DTH2_k127_2709586_6 Redoxin domain protein - - - 0.00000000000000000000000000000000000001026 149.0
DTH2_k127_2718111_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 656.0
DTH2_k127_2718111_2 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 364.0
DTH2_k127_2718111_3 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000535 256.0
DTH2_k127_2718111_4 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000787 200.0
DTH2_k127_2718111_5 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000002398 181.0
DTH2_k127_2718111_6 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.000000000000000000000000000007825 130.0
DTH2_k127_2754976_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 4.952e-269 839.0
DTH2_k127_2754976_1 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
DTH2_k127_2770250_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.687e-294 908.0
DTH2_k127_2770250_1 PFAM Cysteine-rich - - - 1.763e-226 713.0
DTH2_k127_2770250_10 - - - - 0.00000004448 58.0
DTH2_k127_2770250_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.017e-210 663.0
DTH2_k127_2770250_3 glycolate oxidase subunit GlcD - - - 4.604e-203 643.0
DTH2_k127_2770250_4 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 521.0
DTH2_k127_2770250_5 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
DTH2_k127_2770250_6 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002046 270.0
DTH2_k127_2770250_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000002769 225.0
DTH2_k127_2770250_8 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004178 220.0
DTH2_k127_2770250_9 psiF repeat - - - 0.00000000000000000001688 102.0
DTH2_k127_2774469_0 MASE1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 312.0
DTH2_k127_2774469_1 Signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000004115 256.0
DTH2_k127_2774469_2 LuxR family transcriptional regulator K13041 - - 0.000000000000000000000000000000000000000000000000000005935 206.0
DTH2_k127_2774469_3 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.0000000000000000000000000000000000000000000000000001126 207.0
DTH2_k127_2780459_0 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000000000000005877 179.0
DTH2_k127_2780459_1 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000009556 183.0
DTH2_k127_2780459_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000612 158.0
DTH2_k127_2780459_3 Copper binding periplasmic protein CusF - - - 0.0000000000000000002814 95.0
DTH2_k127_2780459_4 ATP-independent chaperone mediated protein folding - - - 0.0000000000002816 79.0
DTH2_k127_2805993_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 384.0
DTH2_k127_2805993_1 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 325.0
DTH2_k127_2805993_2 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000000004247 154.0
DTH2_k127_2805993_3 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.000000001199 68.0
DTH2_k127_2823430_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.476e-321 999.0
DTH2_k127_2823430_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 585.0
DTH2_k127_2823430_2 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000003542 188.0
DTH2_k127_2823430_3 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000001763 127.0
DTH2_k127_2842987_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1139.0
DTH2_k127_2842987_1 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 502.0
DTH2_k127_2842987_10 - - - - 0.000000000000000000000000000000000000000000002167 179.0
DTH2_k127_2842987_11 - - - - 0.0000000000000000000000000000000000000001052 169.0
DTH2_k127_2842987_13 - - - - 0.0000002214 57.0
DTH2_k127_2842987_2 Divalent cation transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 419.0
DTH2_k127_2842987_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 406.0
DTH2_k127_2842987_4 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 394.0
DTH2_k127_2842987_5 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 367.0
DTH2_k127_2842987_6 aldo-keto reductase (NADP) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 357.0
DTH2_k127_2842987_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002674 262.0
DTH2_k127_2842987_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000004102 220.0
DTH2_k127_2842987_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000009029 219.0
DTH2_k127_2855830_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 8.847e-237 741.0
DTH2_k127_2855830_1 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000001094 107.0
DTH2_k127_2902801_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 429.0
DTH2_k127_2902801_1 Peptidase M15 K03791 - - 0.000000000000000000000000000000000000000000000000000000000000006739 222.0
DTH2_k127_2902801_2 Cytochrome c - - - 0.00000000000000000000000006828 114.0
DTH2_k127_295753_0 DNA polymerase X family K02347 - - 1.544e-256 802.0
DTH2_k127_295753_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 1.143e-201 640.0
DTH2_k127_295753_10 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000001799 108.0
DTH2_k127_295753_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 546.0
DTH2_k127_295753_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 529.0
DTH2_k127_295753_4 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 410.0
DTH2_k127_295753_5 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 305.0
DTH2_k127_295753_6 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 312.0
DTH2_k127_295753_7 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000007291 190.0
DTH2_k127_295753_8 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000005802 143.0
DTH2_k127_295753_9 metal cluster binding - - - 0.000000000000000000000000000003496 130.0
DTH2_k127_3012929_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1384.0
DTH2_k127_3012929_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.115e-232 728.0
DTH2_k127_3012929_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.404e-226 708.0
DTH2_k127_3012929_3 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 442.0
DTH2_k127_3012929_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000008339 127.0
DTH2_k127_3012929_5 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000005172 77.0
DTH2_k127_3026245_0 Response regulator receiver K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 598.0
DTH2_k127_3026245_1 PFAM Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 537.0
DTH2_k127_3026245_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001618 261.0
DTH2_k127_3026245_3 - - - - 0.000000000000000000000000005954 120.0
DTH2_k127_3026245_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002447 106.0
DTH2_k127_3026245_5 Sel1-like repeats. K07126 - - 0.000000000000001363 86.0
DTH2_k127_3030415_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.685e-250 782.0
DTH2_k127_3030415_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 389.0
DTH2_k127_3030415_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000001452 235.0
DTH2_k127_3030415_3 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000000002196 236.0
DTH2_k127_3030415_4 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000619 183.0
DTH2_k127_3030415_5 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000001218 189.0
DTH2_k127_3036144_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 7.706e-270 834.0
DTH2_k127_3036144_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 9.272e-214 672.0
DTH2_k127_3036144_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 511.0
DTH2_k127_3036144_3 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
DTH2_k127_3036144_4 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 407.0
DTH2_k127_3036144_5 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 383.0
DTH2_k127_3036144_6 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000005061 149.0
DTH2_k127_3036144_7 FR47-like protein - - - 0.00000000000000000000000006704 110.0
DTH2_k127_306021_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1428.0
DTH2_k127_306021_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 475.0
DTH2_k127_306021_2 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 471.0
DTH2_k127_306021_3 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 388.0
DTH2_k127_306021_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 265.0
DTH2_k127_307909_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 477.0
DTH2_k127_307909_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 451.0
DTH2_k127_307909_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000007452 75.0
DTH2_k127_3095742_0 PFAM Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 467.0
DTH2_k127_3095742_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 379.0
DTH2_k127_3095742_2 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
DTH2_k127_3095742_3 Iron-sulfur cluster assembly transcription factor IscR K13643 - - 0.000000000000000000000000000000000000000000000000000000000000001707 221.0
DTH2_k127_3095742_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000001525 165.0
DTH2_k127_3095742_5 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000007959 162.0
DTH2_k127_3095742_6 - - - - 0.000000000000000000000000000000000001337 148.0
DTH2_k127_3102039_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22015 - 1.17.1.9,1.17.99.7 3.657e-270 839.0
DTH2_k127_3102039_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 291.0
DTH2_k127_3102039_2 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000009149 131.0
DTH2_k127_3102039_3 Protein of unknown function (DUF2889) - - - 0.000000004419 62.0
DTH2_k127_3107872_0 4Fe-4S binding domain - - - 0.0 1040.0
DTH2_k127_3107872_1 Cytochrome C oxidase subunit II, periplasmic domain protein K00376 - 1.7.2.4 0.0 1010.0
DTH2_k127_3107872_2 Periplasmic copper-binding protein (NosD) K07218 - - 2.111e-211 670.0
DTH2_k127_3107872_3 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 427.0
DTH2_k127_3107872_4 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 402.0
DTH2_k127_3107872_5 NosL K19342 - - 0.000000000000000000000000000000000000000000000000000000000000002193 234.0
DTH2_k127_3107872_6 domain, Protein - - - 0.000000000000000000000000000000000000000000000005737 177.0
DTH2_k127_3107872_7 - - - - 0.0000000000000000000000000000000001416 139.0
DTH2_k127_3107872_8 - - - - 0.000000000000000000002895 96.0
DTH2_k127_3116892_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008386 531.0
DTH2_k127_3116892_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000003062 198.0
DTH2_k127_3116892_2 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000006969 128.0
DTH2_k127_3137176_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 445.0
DTH2_k127_3137176_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 393.0
DTH2_k127_3137176_2 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 319.0
DTH2_k127_3137176_3 - - - - 0.0000000000000000000000000000000000000000000000000000003984 206.0
DTH2_k127_3137176_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000452 172.0
DTH2_k127_3137176_5 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000003518 178.0
DTH2_k127_3172610_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1260.0
DTH2_k127_3172610_1 PFAM Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 542.0
DTH2_k127_3172610_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 284.0
DTH2_k127_3172610_3 Protein of unknown function (DUF2934) - - - 0.000001136 53.0
DTH2_k127_3172660_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 533.0
DTH2_k127_3172660_1 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 523.0
DTH2_k127_3172660_2 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 398.0
DTH2_k127_3172660_3 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 278.0
DTH2_k127_3172660_4 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000003962 179.0
DTH2_k127_3172660_5 lipid carrier protein - - - 0.0000000000000000000000000000000000004101 156.0
DTH2_k127_3172660_7 - - - - 0.0000000009836 61.0
DTH2_k127_3173633_0 Aminotransferase K01845 - 5.4.3.8 1.424e-213 669.0
DTH2_k127_3173633_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 544.0
DTH2_k127_3173633_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
DTH2_k127_3173633_3 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000001681 235.0
DTH2_k127_3173633_4 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000003151 59.0
DTH2_k127_3180209_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 461.0
DTH2_k127_3180209_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.000000000000000000000000000000000000000000000000000000000000009146 228.0
DTH2_k127_3180209_2 Phosphotransferase enzyme family - - - 0.000000000002186 75.0
DTH2_k127_3204756_0 Sigma-54 interaction domain K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 604.0
DTH2_k127_3204756_1 Belongs to the UPF0337 (CsbD) family - - - 0.000000776 55.0
DTH2_k127_3204756_2 - - - - 0.00006038 51.0
DTH2_k127_3207142_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.669e-218 688.0
DTH2_k127_3207142_1 modulator of DNA gyrase K03592 - - 5.894e-199 628.0
DTH2_k127_3207142_10 - - - - 0.000000000000000000000000000000000000002991 154.0
DTH2_k127_3207142_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000004855 87.0
DTH2_k127_3207142_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 600.0
DTH2_k127_3207142_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 501.0
DTH2_k127_3207142_4 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 338.0
DTH2_k127_3207142_5 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 302.0
DTH2_k127_3207142_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003661 244.0
DTH2_k127_3207142_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
DTH2_k127_3207142_8 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
DTH2_k127_3207142_9 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000001031 159.0
DTH2_k127_3242990_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.974e-211 665.0
DTH2_k127_3242990_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 405.0
DTH2_k127_3242990_11 - - - - 0.0000000000006056 81.0
DTH2_k127_3242990_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 389.0
DTH2_k127_3242990_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 377.0
DTH2_k127_3242990_4 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 374.0
DTH2_k127_3242990_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 332.0
DTH2_k127_3242990_6 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
DTH2_k127_3242990_7 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 282.0
DTH2_k127_3242990_8 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001301 286.0
DTH2_k127_3242990_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003018 173.0
DTH2_k127_3254657_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 548.0
DTH2_k127_3254657_1 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 334.0
DTH2_k127_3254657_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
DTH2_k127_3254657_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
DTH2_k127_3254657_4 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
DTH2_k127_3254657_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000001576 56.0
DTH2_k127_3261476_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1215.0
DTH2_k127_3261476_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000237 260.0
DTH2_k127_3261476_2 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000001592 154.0
DTH2_k127_3261476_3 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000000000004818 156.0
DTH2_k127_3261476_4 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000001392 137.0
DTH2_k127_3261476_5 - - - - 0.0000000000000000000001172 104.0
DTH2_k127_3261476_6 Glycine-zipper domain - - - 0.0000000000000000000002625 99.0
DTH2_k127_3261476_7 Biotin-lipoyl like K07799 - - 0.000000000000000512 79.0
DTH2_k127_3261476_8 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000001395 68.0
DTH2_k127_3270799_0 GMP synthase C terminal domain K01951 - 6.3.5.2 7.168e-299 921.0
DTH2_k127_3270799_1 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000007659 145.0
DTH2_k127_3270799_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000001659 136.0
DTH2_k127_3270799_3 - - - - 0.00008408 53.0
DTH2_k127_3271301_0 Domain of unknown function (DUF3400) - - - 0.0 1268.0
DTH2_k127_3271301_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 414.0
DTH2_k127_3271301_2 membrane - - - 0.000000000000000000000000000000000000000000000009304 177.0
DTH2_k127_3271301_3 Protein of unknown function DUF58 - - - 0.00000000000008026 85.0
DTH2_k127_328027_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.229e-230 725.0
DTH2_k127_328027_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 473.0
DTH2_k127_328027_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000247 102.0
DTH2_k127_328027_3 - - - - 0.00000000000000000000001133 105.0
DTH2_k127_328027_4 - - - - 0.000000000000000000001682 96.0
DTH2_k127_3293516_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 4.682e-212 662.0
DTH2_k127_3293516_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 584.0
DTH2_k127_3293516_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 565.0
DTH2_k127_3293516_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 406.0
DTH2_k127_3293516_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
DTH2_k127_3293516_5 transcriptional - - - 0.0000000000000000000000000000000000000000187 157.0
DTH2_k127_3293516_6 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000002489 130.0
DTH2_k127_3293516_7 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000002259 86.0
DTH2_k127_3308691_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 328.0
DTH2_k127_3308691_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000003509 224.0
DTH2_k127_3308691_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000001045 210.0
DTH2_k127_3308691_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000139 204.0
DTH2_k127_3308691_4 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000401 99.0
DTH2_k127_3312536_0 acyl-CoA dehydrogenase K06445 - - 0.0 1037.0
DTH2_k127_3312536_1 Acyl-CoA dehydrogenase N terminal K20035 - - 5.146e-258 807.0
DTH2_k127_3312536_2 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 425.0
DTH2_k127_3312536_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 404.0
DTH2_k127_3312536_4 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 392.0
DTH2_k127_3312536_5 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 378.0
DTH2_k127_3312536_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
DTH2_k127_3312536_7 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000004748 244.0
DTH2_k127_3312536_8 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000003218 157.0
DTH2_k127_3329791_0 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 456.0
DTH2_k127_3329791_1 Multi-copper K06324,K22350 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 465.0
DTH2_k127_3329791_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 388.0
DTH2_k127_3329791_3 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
DTH2_k127_3329791_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000000007162 224.0
DTH2_k127_3329791_5 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000005929 221.0
DTH2_k127_3339088_0 Iron-sulfur cluster-binding domain K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 555.0
DTH2_k127_3339088_1 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 463.0
DTH2_k127_3339088_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 389.0
DTH2_k127_3339088_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 325.0
DTH2_k127_3339088_4 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002172 264.0
DTH2_k127_3357277_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1317.0
DTH2_k127_3357277_1 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 509.0
DTH2_k127_3357277_10 COG2199 FOG GGDEF domain - - - 0.00000000000000000000000000000000006799 146.0
DTH2_k127_3357277_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000001715 125.0
DTH2_k127_3357277_12 diguanylate cyclase - - - 0.0000000000000000000000000002091 128.0
DTH2_k127_3357277_13 Integral membrane protein, TerC family K05794 - - 0.000000000000005225 76.0
DTH2_k127_3357277_2 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 422.0
DTH2_k127_3357277_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 371.0
DTH2_k127_3357277_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 348.0
DTH2_k127_3357277_5 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 320.0
DTH2_k127_3357277_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001243 251.0
DTH2_k127_3357277_7 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
DTH2_k127_3357277_8 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000006193 182.0
DTH2_k127_3357277_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000000000000000000000000000000000000006372 173.0
DTH2_k127_3372647_0 Fe-S oxidoreductase K21834 - - 1.152e-267 829.0
DTH2_k127_3372647_1 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.12e-220 689.0
DTH2_k127_3372647_10 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000006576 183.0
DTH2_k127_3372647_11 DsrC like protein - - - 0.000000000000000000000000000000000000000000007216 164.0
DTH2_k127_3372647_12 DsrH like protein K07237 - - 0.000000000000000000000000000000388 125.0
DTH2_k127_3372647_13 - - - - 0.00000000000000000000001008 102.0
DTH2_k127_3372647_2 NADPH-dependent glutamate synthase beta - - - 2.024e-219 689.0
DTH2_k127_3372647_3 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 1.696e-217 677.0
DTH2_k127_3372647_4 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 349.0
DTH2_k127_3372647_5 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000000000000001699 214.0
DTH2_k127_3372647_6 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
DTH2_k127_3372647_7 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000002056 201.0
DTH2_k127_3372647_8 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000000000000000000000000000003575 215.0
DTH2_k127_3372647_9 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000000005865 188.0
DTH2_k127_3375619_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 578.0
DTH2_k127_3375619_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 323.0
DTH2_k127_3375619_2 Transcriptional regulator K13641 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004443 277.0
DTH2_k127_3375619_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000001746 209.0
DTH2_k127_3375619_4 Protein conserved in bacteria - - - 0.000000003166 59.0
DTH2_k127_3411126_0 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
DTH2_k127_3411126_1 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000001524 241.0
DTH2_k127_3411126_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000001686 210.0
DTH2_k127_3448711_0 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 389.0
DTH2_k127_3448711_1 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000000000000001452 194.0
DTH2_k127_3448711_2 PFAM response regulator receiver K07659 - - 0.0000000000000000000000000000000000000003764 150.0
DTH2_k127_3448711_3 serine-type endopeptidase activity K04771,K07126 - 3.4.21.107 0.0000002722 58.0
DTH2_k127_3458485_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1099.0
DTH2_k127_3458485_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 539.0
DTH2_k127_3458485_2 Thioesterase superfamily K10806 - - 0.00000000000000000000000000002446 118.0
DTH2_k127_346399_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.205e-292 910.0
DTH2_k127_346399_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.481e-215 673.0
DTH2_k127_346399_10 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000000000001597 219.0
DTH2_k127_346399_11 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000003263 188.0
DTH2_k127_346399_12 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000008477 111.0
DTH2_k127_346399_13 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000003223 70.0
DTH2_k127_346399_2 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 7.225e-194 611.0
DTH2_k127_346399_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 561.0
DTH2_k127_346399_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 473.0
DTH2_k127_346399_5 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
DTH2_k127_346399_6 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 313.0
DTH2_k127_346399_7 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003709 276.0
DTH2_k127_346399_8 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007832 250.0
DTH2_k127_346399_9 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000279 245.0
DTH2_k127_3486633_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 392.0
DTH2_k127_3486633_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
DTH2_k127_3486633_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000006936 199.0
DTH2_k127_3486633_3 Belongs to the CDS family K00981 - 2.7.7.41 0.000004039 55.0
DTH2_k127_3505727_0 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000000000009813 180.0
DTH2_k127_3505727_1 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000000001066 178.0
DTH2_k127_3505727_2 Uncharacterised protein family (UPF0149) K07039 - - 0.00000000000000000000000000000000000000000000003625 188.0
DTH2_k127_3505727_3 UvrD-like helicase C-terminal domain - - - 0.000000000000000000000000000000000000000001903 159.0
DTH2_k127_3505727_4 Alg9-like mannosyltransferase family K05286 - - 0.0000000001767 74.0
DTH2_k127_3505727_5 - - - - 0.000004184 54.0
DTH2_k127_3514835_0 HELICc2 K03722 - 3.6.4.12 2.226e-274 858.0
DTH2_k127_3514835_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.352e-228 716.0
DTH2_k127_3514835_10 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000001073 213.0
DTH2_k127_3514835_11 Phasin protein - - - 0.00000000000000000000000000000000000000003474 159.0
DTH2_k127_3514835_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000002093 86.0
DTH2_k127_3514835_13 - - - - 0.0000000001057 66.0
DTH2_k127_3514835_2 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 3.797e-202 649.0
DTH2_k127_3514835_3 Cytochrome c bacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 608.0
DTH2_k127_3514835_4 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 542.0
DTH2_k127_3514835_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 426.0
DTH2_k127_3514835_6 PFAM Zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 362.0
DTH2_k127_3514835_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 324.0
DTH2_k127_3514835_8 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 328.0
DTH2_k127_3514835_9 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003135 252.0
DTH2_k127_3558616_0 AMP-dependent synthetase - - - 3.69e-317 991.0
DTH2_k127_3558616_1 protein synthesis factor, GTP-binding K06207 - - 1.358e-307 951.0
DTH2_k127_3558616_2 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 9.589e-273 848.0
DTH2_k127_3558616_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 616.0
DTH2_k127_3558616_4 dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 312.0
DTH2_k127_3558616_5 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000006027 149.0
DTH2_k127_3558616_6 periplasmic protein - - - 0.000000000000000001455 98.0
DTH2_k127_3627996_0 4Fe-4S double cluster binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 582.0
DTH2_k127_3627996_1 COG0695 Glutaredoxin and related proteins - - - 0.0000000000000000000000000000002785 129.0
DTH2_k127_3627996_2 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000009838 87.0
DTH2_k127_3627996_3 SdpI/YhfL protein family - - - 0.000000000000000001734 97.0
DTH2_k127_3632501_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 525.0
DTH2_k127_3632501_1 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000002701 187.0
DTH2_k127_3632794_0 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 472.0
DTH2_k127_3632794_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 360.0
DTH2_k127_3632794_2 Protein of unknown function DUF72 - - - 0.0000000000002529 74.0
DTH2_k127_3640178_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1103.0
DTH2_k127_3640178_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 346.0
DTH2_k127_3640178_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000006497 246.0
DTH2_k127_3640178_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000000000000000002551 206.0
DTH2_k127_365561_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 6.754e-281 878.0
DTH2_k127_365561_1 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 344.0
DTH2_k127_365561_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000001152 151.0
DTH2_k127_3738785_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 477.0
DTH2_k127_3738785_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 344.0
DTH2_k127_3738785_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
DTH2_k127_3738785_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000005027 206.0
DTH2_k127_3738785_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000001843 147.0
DTH2_k127_3738785_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000005873 145.0
DTH2_k127_3738785_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000004978 69.0
DTH2_k127_3769657_0 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 377.0
DTH2_k127_3769657_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000001414 239.0
DTH2_k127_3769657_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000003011 220.0
DTH2_k127_3769657_3 MazG-like family - - - 0.000000000000000000000000000000000002254 141.0
DTH2_k127_3769657_4 GDSL-like Lipase/Acylhydrolase - - - 0.000001662 61.0
DTH2_k127_3792706_0 Protein of unknown function - - - 0.0 1135.0
DTH2_k127_3792706_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 475.0
DTH2_k127_3792706_2 Carbon-nitrogen hydrolase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 349.0
DTH2_k127_3792706_3 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 0.00000000000001558 74.0
DTH2_k127_3830926_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1512.0
DTH2_k127_3830926_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1011.0
DTH2_k127_3830926_10 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 385.0
DTH2_k127_3830926_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000008311 236.0
DTH2_k127_3830926_12 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000002098 157.0
DTH2_k127_3830926_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 3.427e-194 617.0
DTH2_k127_3830926_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 513.0
DTH2_k127_3830926_4 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 484.0
DTH2_k127_3830926_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 454.0
DTH2_k127_3830926_6 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
DTH2_k127_3830926_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 419.0
DTH2_k127_3830926_8 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
DTH2_k127_3830926_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
DTH2_k127_3848773_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 381.0
DTH2_k127_3848773_1 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 377.0
DTH2_k127_3848773_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 297.0
DTH2_k127_3848773_3 transcriptional - - - 0.00000000000000000000000000000000002064 136.0
DTH2_k127_3868579_0 Tripartite tricarboxylate transporter TctA family K07793 - - 6.552e-256 796.0
DTH2_k127_3868579_1 AMP-binding enzyme C-terminal domain - - - 4.51e-237 744.0
DTH2_k127_3868579_10 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000003318 160.0
DTH2_k127_3868579_11 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000008561 132.0
DTH2_k127_3868579_12 - - - - 0.0000000000000001297 81.0
DTH2_k127_3868579_13 Ion channel - - - 0.0000000000000002405 88.0
DTH2_k127_3868579_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 530.0
DTH2_k127_3868579_3 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 463.0
DTH2_k127_3868579_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 382.0
DTH2_k127_3868579_5 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
DTH2_k127_3868579_6 PFAM AMP-dependent synthetase and ligase K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004356 241.0
DTH2_k127_3868579_7 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000002719 228.0
DTH2_k127_3868579_8 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000007065 169.0
DTH2_k127_3868579_9 - - - - 0.000000000000000000000000000000000000000001338 172.0
DTH2_k127_3870764_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1089.0
DTH2_k127_3870764_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
DTH2_k127_3870764_2 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000001233 199.0
DTH2_k127_3870764_3 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000003474 162.0
DTH2_k127_3879827_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.3e-220 695.0
DTH2_k127_3879827_1 TIGRFAM type I secretion system ATPase K06148,K12536 - - 2.628e-196 628.0
DTH2_k127_3879827_10 AMMECR1 - - - 0.000000000000000000000000000000000000000000000000000000000000000005606 233.0
DTH2_k127_3879827_11 - K09004 - - 0.000000000000000000000000000000000000000000000000000000002982 205.0
DTH2_k127_3879827_12 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000001025 144.0
DTH2_k127_3879827_2 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 568.0
DTH2_k127_3879827_3 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022,K12537 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 507.0
DTH2_k127_3879827_4 Member of a two-component regulatory system K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 373.0
DTH2_k127_3879827_5 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 355.0
DTH2_k127_3879827_6 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 318.0
DTH2_k127_3879827_7 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 313.0
DTH2_k127_3879827_8 Animal haem peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 295.0
DTH2_k127_3879827_9 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 267.0
DTH2_k127_390779_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 3.77e-209 659.0
DTH2_k127_390779_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 373.0
DTH2_k127_390779_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
DTH2_k127_390779_3 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000006526 239.0
DTH2_k127_390779_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000002796 96.0
DTH2_k127_3918237_0 HI0933-like protein - - - 3.42e-211 661.0
DTH2_k127_3918237_1 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 378.0
DTH2_k127_3918237_2 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 357.0
DTH2_k127_3918237_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 332.0
DTH2_k127_3918237_4 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 336.0
DTH2_k127_3918237_5 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000002087 233.0
DTH2_k127_3918237_6 PAS fold - - - 0.0000000000000000000000000000000000000000000000000001269 212.0
DTH2_k127_3918237_7 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000005266 186.0
DTH2_k127_3918237_8 - - - - 0.000000000000000000003367 99.0
DTH2_k127_3929370_0 FeS assembly protein SufB K09014 - - 8.926e-274 848.0
DTH2_k127_3929370_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 589.0
DTH2_k127_3929370_10 PaaD-like protein - - - 0.00000000000000000000000000000000000002592 146.0
DTH2_k127_3929370_11 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000004651 128.0
DTH2_k127_3929370_12 NnrU protein - - - 0.000000418 53.0
DTH2_k127_3929370_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 456.0
DTH2_k127_3929370_3 HD domain K07814,K13815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 404.0
DTH2_k127_3929370_4 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
DTH2_k127_3929370_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
DTH2_k127_3929370_6 asparaginase K01424,K13051 GO:0003674,GO:0003824,GO:0004067,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008798,GO:0010467,GO:0016485,GO:0016540,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.5,3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 310.0
DTH2_k127_3929370_7 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
DTH2_k127_3929370_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002666 172.0
DTH2_k127_3929370_9 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.00000000000000000000000000000000000000006405 154.0
DTH2_k127_3938687_0 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 548.0
DTH2_k127_3938687_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 509.0
DTH2_k127_3938687_10 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000001019 165.0
DTH2_k127_3938687_11 PLD-like domain - - - 0.00000000000000000000000000000000000000007312 172.0
DTH2_k127_3938687_12 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000002256 137.0
DTH2_k127_3938687_13 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000001255 132.0
DTH2_k127_3938687_14 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000001896 136.0
DTH2_k127_3938687_15 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002148 90.0
DTH2_k127_3938687_16 - - - - 0.000000000009444 76.0
DTH2_k127_3938687_17 - - - - 0.0000007764 55.0
DTH2_k127_3938687_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 508.0
DTH2_k127_3938687_3 AAA domain (dynein-related subfamily) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 469.0
DTH2_k127_3938687_4 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 456.0
DTH2_k127_3938687_5 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 456.0
DTH2_k127_3938687_6 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
DTH2_k127_3938687_7 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
DTH2_k127_3938687_8 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
DTH2_k127_3938687_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000005212 241.0
DTH2_k127_3956991_0 argininosuccinate lyase K01755 - 4.3.2.1 1.372e-230 722.0
DTH2_k127_3956991_1 PFAM multicopper oxidase type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 576.0
DTH2_k127_3956991_2 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 366.0
DTH2_k127_3956991_3 PFAM Fructosamine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 377.0
DTH2_k127_3956991_4 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000004438 157.0
DTH2_k127_3956991_5 Domain of unknown function (DUF4124) - - - 0.0000000005101 69.0
DTH2_k127_3982922_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1429.0
DTH2_k127_3982922_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 6.484e-199 649.0
DTH2_k127_3982922_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000003652 137.0
DTH2_k127_3982922_3 - - - - 0.0000000000000000003933 94.0
DTH2_k127_3984339_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 389.0
DTH2_k127_3984339_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 396.0
DTH2_k127_3984339_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 377.0
DTH2_k127_3984339_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
DTH2_k127_3984339_4 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001044 278.0
DTH2_k127_3984339_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000003111 207.0
DTH2_k127_3984339_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000005394 205.0
DTH2_k127_4000016_0 type IV-A pilus assembly ATPase PilB K02652 - - 4.614e-251 786.0
DTH2_k127_4000016_1 PFAM type II secretion system K02653 - - 2.504e-201 632.0
DTH2_k127_4000016_2 Domain of unknown function DUF21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 571.0
DTH2_k127_4000016_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 431.0
DTH2_k127_4000016_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 387.0
DTH2_k127_4000016_5 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 343.0
DTH2_k127_4000016_6 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 308.0
DTH2_k127_4000016_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000298 219.0
DTH2_k127_4000016_8 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000004378 93.0
DTH2_k127_4002331_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 525.0
DTH2_k127_4002331_1 abc transporter K06158 - - 0.00000000001378 67.0
DTH2_k127_4084359_0 Insecticidal toxin complex protein TcaC - - - 2.724e-239 793.0
DTH2_k127_4084359_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.701e-220 688.0
DTH2_k127_4088901_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 567.0
DTH2_k127_4088901_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 464.0
DTH2_k127_4088901_10 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.00000001195 56.0
DTH2_k127_4088901_2 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 404.0
DTH2_k127_4088901_3 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 378.0
DTH2_k127_4088901_4 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 347.0
DTH2_k127_4088901_5 alcohol dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 311.0
DTH2_k127_4088901_6 17 kDa surface antigen - - - 0.0000000000000000000000000000000004826 140.0
DTH2_k127_4088901_7 - - - - 0.00000000000000000000005491 105.0
DTH2_k127_4088901_8 - - - - 0.000000000000000000008024 105.0
DTH2_k127_4088901_9 AP2 domain - - - 0.00000000000000003662 87.0
DTH2_k127_4088969_0 von Willebrand factor, type A - - - 0.0 1188.0
DTH2_k127_4088969_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 3.082e-296 912.0
DTH2_k127_4088969_10 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000003102 271.0
DTH2_k127_4088969_11 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001751 267.0
DTH2_k127_4088969_12 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000007148 243.0
DTH2_k127_4088969_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001006 228.0
DTH2_k127_4088969_14 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000006292 217.0
DTH2_k127_4088969_15 META domain - - - 0.0000000000000000000000000000000000000000000000000000000166 210.0
DTH2_k127_4088969_16 - - - - 0.000000000000000000000000000000000000000000000003008 182.0
DTH2_k127_4088969_17 regulation of methylation-dependent chromatin silencing K03684,K09968 - 3.1.13.5 0.00000000000000000000000000000000000000005082 155.0
DTH2_k127_4088969_18 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000305 138.0
DTH2_k127_4088969_19 TIGRFAM phasin family protein - - - 0.000000000000000000000000000000007399 132.0
DTH2_k127_4088969_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 566.0
DTH2_k127_4088969_21 - - - - 0.000000000000000001754 91.0
DTH2_k127_4088969_22 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000008739 86.0
DTH2_k127_4088969_24 nitrogen regulatory protein PII - - - 0.000000004619 57.0
DTH2_k127_4088969_3 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 488.0
DTH2_k127_4088969_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 472.0
DTH2_k127_4088969_5 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 448.0
DTH2_k127_4088969_6 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 420.0
DTH2_k127_4088969_7 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 388.0
DTH2_k127_4088969_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 342.0
DTH2_k127_4088969_9 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
DTH2_k127_4098082_0 B12 binding domain K00548 - 2.1.1.13 0.0 1718.0
DTH2_k127_4098082_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 5.42e-242 756.0
DTH2_k127_4098082_2 (GGDEF) domain K21024 - 3.1.4.52 6.166e-199 655.0
DTH2_k127_4098082_3 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
DTH2_k127_4098082_4 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000006289 222.0
DTH2_k127_4098082_5 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000008761 235.0
DTH2_k127_4098082_6 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000001613 207.0
DTH2_k127_4098082_7 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000006262 164.0
DTH2_k127_4098082_8 protein conserved in bacteria K09806 - - 0.000000000000000000000002086 105.0
DTH2_k127_41036_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 306.0
DTH2_k127_41036_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 307.0
DTH2_k127_41036_2 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001256 283.0
DTH2_k127_41036_3 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001309 264.0
DTH2_k127_41036_4 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
DTH2_k127_41036_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000005293 190.0
DTH2_k127_41036_6 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000001034 166.0
DTH2_k127_41036_7 SpoIIAA-like - - - 0.00000000000000000000000000000000002158 138.0
DTH2_k127_41036_8 Ca2 -binding protein (EF-Hand superfamily - - - 0.0000000000003283 79.0
DTH2_k127_41036_9 Protein of unknown function (DUF3106) - - - 0.0001157 51.0
DTH2_k127_4113274_0 ribonuclease, Rne Rng family K08301 - - 3.363e-235 746.0
DTH2_k127_4113274_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000575 271.0
DTH2_k127_4113274_2 integral membrane protein K02221 - - 0.0000000000000000000000000000000000000000000000000000001149 201.0
DTH2_k127_4113274_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000009831 194.0
DTH2_k127_4113274_4 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000004411 118.0
DTH2_k127_4113274_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00004633 46.0
DTH2_k127_4116218_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
DTH2_k127_4116218_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000005026 223.0
DTH2_k127_4116218_2 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003449 225.0
DTH2_k127_4116218_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000104 203.0
DTH2_k127_4117236_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.817e-207 653.0
DTH2_k127_4117236_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
DTH2_k127_4117236_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000004713 218.0
DTH2_k127_4128075_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 479.0
DTH2_k127_4128075_1 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 401.0
DTH2_k127_4128075_2 Universal stress protein - - - 0.00000000000000000000000000000000001151 144.0
DTH2_k127_4128075_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000004171 114.0
DTH2_k127_4131829_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 8.387e-223 710.0
DTH2_k127_4131829_1 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000007035 261.0
DTH2_k127_4135094_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 404.0
DTH2_k127_4135094_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 340.0
DTH2_k127_4135094_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000004578 145.0
DTH2_k127_4135094_3 Biopolymer transport protein K03559 - - 0.000000000000000000000000000001344 128.0
DTH2_k127_4135760_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 383.0
DTH2_k127_4135760_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
DTH2_k127_4135760_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000001105 94.0
DTH2_k127_4141902_0 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 467.0
DTH2_k127_4141902_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 467.0
DTH2_k127_4141902_10 Fe-S protein - - - 0.00006946 49.0
DTH2_k127_4141902_11 DnaJ-class molecular chaperone with C-terminal Zn finger - - - 0.0005093 50.0
DTH2_k127_4141902_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 360.0
DTH2_k127_4141902_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 321.0
DTH2_k127_4141902_4 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000002046 247.0
DTH2_k127_4141902_5 Acyl carrier protein phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006756 242.0
DTH2_k127_4141902_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000003643 162.0
DTH2_k127_4141902_7 - - - - 0.000000000000000000000000000000000000000211 156.0
DTH2_k127_4141902_8 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000005105 104.0
DTH2_k127_4141902_9 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000004181 87.0
DTH2_k127_4153542_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1230.0
DTH2_k127_4153542_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 6.867e-296 918.0
DTH2_k127_4153542_10 Methyl-transferase K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000008597 243.0
DTH2_k127_4153542_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000000003538 138.0
DTH2_k127_4153542_12 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000005616 132.0
DTH2_k127_4153542_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 9.232e-231 719.0
DTH2_k127_4153542_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 457.0
DTH2_k127_4153542_4 Multicopper oxidase K22349 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
DTH2_k127_4153542_5 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 356.0
DTH2_k127_4153542_6 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 337.0
DTH2_k127_4153542_7 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 327.0
DTH2_k127_4153542_8 regulatory protein Crp K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002827 265.0
DTH2_k127_4153542_9 methyltransferase K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007268 249.0
DTH2_k127_4154625_0 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 365.0
DTH2_k127_4154625_1 - - - - 0.00000000000000000000000000000000000000006623 160.0
DTH2_k127_4154625_2 Ion channel - - - 0.000000000000000000000000006671 113.0
DTH2_k127_4162354_0 Cysteine-rich domain - - - 8.387e-229 718.0
DTH2_k127_4162354_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
DTH2_k127_4162354_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006853 282.0
DTH2_k127_4162354_3 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002192 256.0
DTH2_k127_4162354_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000002537 214.0
DTH2_k127_4162354_5 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000004447 191.0
DTH2_k127_4172605_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 5.66e-211 665.0
DTH2_k127_4172605_1 COG0569 K transport systems, NAD-binding component K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000002175 230.0
DTH2_k127_4172605_2 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus - - - 0.0000000000000000000000000000001463 128.0
DTH2_k127_4180424_0 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 483.0
DTH2_k127_4180424_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000001654 261.0
DTH2_k127_4180424_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003038 259.0
DTH2_k127_4180424_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001079 261.0
DTH2_k127_418367_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 603.0
DTH2_k127_418367_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 460.0
DTH2_k127_418367_2 Sugar fermentation stimulation protein K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 304.0
DTH2_k127_418367_3 VWA-like domain (DUF2201) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002273 278.0
DTH2_k127_4193026_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 529.0
DTH2_k127_4193026_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 442.0
DTH2_k127_4193026_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 406.0
DTH2_k127_4193026_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
DTH2_k127_4193026_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000002806 153.0
DTH2_k127_4193026_5 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.0000000000000000000000000000000000001355 147.0
DTH2_k127_4193026_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000002562 97.0
DTH2_k127_4195121_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1065.0
DTH2_k127_4195121_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.449e-235 733.0
DTH2_k127_4195121_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000009024 72.0
DTH2_k127_4195121_3 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000002367 70.0
DTH2_k127_4208433_0 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
DTH2_k127_4208433_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000009666 224.0
DTH2_k127_4208433_2 type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
DTH2_k127_4217787_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 440.0
DTH2_k127_4217787_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000152 203.0
DTH2_k127_4217787_2 formate dehydrogenase - - - 0.0000000000001915 79.0
DTH2_k127_4220621_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 2458.0
DTH2_k127_4220621_1 Multicopper oxidase K22349 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 415.0
DTH2_k127_4220621_2 PFAM Cytochrome c assembly protein - - - 0.0000000000000000003663 99.0
DTH2_k127_4220621_3 PFAM Ankyrin K10799 - 2.4.2.30 0.00000000004488 68.0
DTH2_k127_4226941_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2343.0
DTH2_k127_4226941_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2050.0
DTH2_k127_4226941_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1196.0
DTH2_k127_4226941_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.058e-239 743.0
DTH2_k127_4226941_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009877 261.0
DTH2_k127_4226941_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000009138 225.0
DTH2_k127_4226941_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000009053 153.0
DTH2_k127_4226941_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000009923 136.0
DTH2_k127_422765_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1009.0
DTH2_k127_422765_1 Protein of unknown function, DUF255 K06888 - - 1.24e-201 646.0
DTH2_k127_422765_2 - - - - 0.00000000000000000000000000000000000000000000000000004623 190.0
DTH2_k127_4237305_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 467.0
DTH2_k127_4237305_1 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 341.0
DTH2_k127_4237305_2 CHAT domain - - - 0.0000000000000000000000000000000000000000000002133 192.0
DTH2_k127_4268615_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1080.0
DTH2_k127_4268615_1 Translation-initiation factor 2 K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 323.0
DTH2_k127_4268615_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 305.0
DTH2_k127_4268615_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000003604 219.0
DTH2_k127_4268615_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000007642 161.0
DTH2_k127_4268615_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000003035 148.0
DTH2_k127_4268615_6 - - - - 0.00000003059 64.0
DTH2_k127_427285_0 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 583.0
DTH2_k127_427444_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.197e-233 729.0
DTH2_k127_427444_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 518.0
DTH2_k127_427444_10 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000008578 154.0
DTH2_k127_427444_11 positive regulation of growth K01081 - 3.1.3.5 0.00000000000000000000000001165 110.0
DTH2_k127_427444_12 Tetratricopeptide TPR_2 repeat protein - - - 0.000000002383 68.0
DTH2_k127_427444_2 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 503.0
DTH2_k127_427444_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 401.0
DTH2_k127_427444_4 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
DTH2_k127_427444_5 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
DTH2_k127_427444_6 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000006163 266.0
DTH2_k127_427444_7 ApaG domain - - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
DTH2_k127_427444_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000004147 173.0
DTH2_k127_427444_9 PIN domain - - - 0.00000000000000000000000000000000000000000000009327 172.0
DTH2_k127_4299774_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 416.0
DTH2_k127_4299774_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004219 273.0
DTH2_k127_4299774_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000007873 126.0
DTH2_k127_4315090_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 333.0
DTH2_k127_4315090_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000002892 241.0
DTH2_k127_4315090_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000191 179.0
DTH2_k127_4319692_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.439e-319 994.0
DTH2_k127_4319692_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 302.0
DTH2_k127_4319692_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003041 261.0
DTH2_k127_4338503_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 459.0
DTH2_k127_4338503_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 418.0
DTH2_k127_4338503_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 403.0
DTH2_k127_4338503_3 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
DTH2_k127_4338503_4 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000002199 165.0
DTH2_k127_4338503_5 FR47-like protein - - - 0.00000000000003519 74.0
DTH2_k127_4338503_6 response to antibiotic - - - 0.00009347 49.0
DTH2_k127_4356895_0 AAA domain - - - 4.802e-319 995.0
DTH2_k127_4356895_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 3.954e-250 779.0
DTH2_k127_4356895_2 DHH family K07462 - - 8.055e-215 721.0
DTH2_k127_4356895_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 560.0
DTH2_k127_4356895_4 PFAM MgtC SapB transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 510.0
DTH2_k127_4356895_5 PFAM UspA - - - 0.00000000000000000000002294 107.0
DTH2_k127_4356895_6 Protein of unknown function (DUF465) - - - 0.0000000000000005323 81.0
DTH2_k127_4404022_0 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 428.0
DTH2_k127_4404022_1 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000003755 128.0
DTH2_k127_4404022_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000005504 82.0
DTH2_k127_4425187_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 446.0
DTH2_k127_4425187_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003416 256.0
DTH2_k127_4425187_2 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000005261 180.0
DTH2_k127_4425187_3 Virulence factor membrane-bound polymerase, C-terminal - - - 0.0000000000000000000000000000000000000000000001613 180.0
DTH2_k127_4425187_4 - - - - 0.00000000000000000000000000000000000000005765 167.0
DTH2_k127_4444282_0 Nitronate monooxygenase K00459 - 1.13.12.16 6.932e-224 701.0
DTH2_k127_4444282_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 563.0
DTH2_k127_4444282_2 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
DTH2_k127_4444282_3 - - - - 0.0000000006915 65.0
DTH2_k127_4444282_4 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0006269 47.0
DTH2_k127_4469553_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1558.0
DTH2_k127_4469553_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 501.0
DTH2_k127_4469553_10 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000005687 163.0
DTH2_k127_4469553_11 COG3666 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000002701 135.0
DTH2_k127_4469553_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000001434 132.0
DTH2_k127_4469553_13 - - - - 0.0000000001878 71.0
DTH2_k127_4469553_14 - - - - 0.000000007655 64.0
DTH2_k127_4469553_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 504.0
DTH2_k127_4469553_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 432.0
DTH2_k127_4469553_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001376 246.0
DTH2_k127_4469553_5 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000000000000002811 204.0
DTH2_k127_4469553_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000166 187.0
DTH2_k127_4469553_7 - - - - 0.00000000000000000000000000000000000000000000000007419 202.0
DTH2_k127_4469553_8 Chaperone - - - 0.0000000000000000000000000000000000000000000000001227 188.0
DTH2_k127_4469553_9 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000958 164.0
DTH2_k127_4476288_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 308.0
DTH2_k127_4476288_1 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 278.0
DTH2_k127_4476288_2 VanZ like family - - - 0.000000000000000000000000000000000000000001196 170.0
DTH2_k127_4485226_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 394.0
DTH2_k127_4485226_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 343.0
DTH2_k127_4485226_2 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
DTH2_k127_4485226_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 293.0
DTH2_k127_4485226_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.000000000000000000000000000000000000000000002377 169.0
DTH2_k127_4485226_5 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000006324 136.0
DTH2_k127_4492322_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.003e-214 672.0
DTH2_k127_4492322_1 Sodium:solute symporter family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 497.0
DTH2_k127_4492322_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 475.0
DTH2_k127_4492322_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 347.0
DTH2_k127_4492322_4 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 313.0
DTH2_k127_4492322_5 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000002298 175.0
DTH2_k127_4492322_6 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000007192 150.0
DTH2_k127_4492322_7 - - - - 0.00000000000000002335 88.0
DTH2_k127_4492322_8 Recombinase zinc beta ribbon domain K06400 - - 0.000000002296 62.0
DTH2_k127_4571129_0 Belongs to the ClpA ClpB family K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 559.0
DTH2_k127_4571129_1 sulfide dehydrogenase K05301 - 1.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 514.0
DTH2_k127_4571129_10 cytochrome - - - 0.0000000000000002858 83.0
DTH2_k127_4571129_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 373.0
DTH2_k127_4571129_3 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 337.0
DTH2_k127_4571129_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 329.0
DTH2_k127_4571129_5 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 286.0
DTH2_k127_4571129_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
DTH2_k127_4571129_7 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000005352 149.0
DTH2_k127_4571129_8 SpoIIAA-like - - - 0.00000000000000000000000000000000000868 153.0
DTH2_k127_4571129_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000003331 93.0
DTH2_k127_459516_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1064.0
DTH2_k127_459516_1 - - - - 0.000000000000000000000002052 112.0
DTH2_k127_4605377_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 379.0
DTH2_k127_4605377_1 HEPN domain - - - 0.000000000000002107 81.0
DTH2_k127_4605377_2 Nucleotidyltransferase domain - - - 0.0001189 51.0
DTH2_k127_4605377_3 - - - - 0.0007364 48.0
DTH2_k127_4624084_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
DTH2_k127_4624084_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 317.0
DTH2_k127_4624084_2 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009398 245.0
DTH2_k127_4624084_3 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000164 200.0
DTH2_k127_4624084_4 PFAM transcription elongation factor GreA GreB - - - 0.00000000000000000000000000000000000000000000007137 178.0
DTH2_k127_4639238_0 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 8.784e-309 952.0
DTH2_k127_4639238_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
DTH2_k127_4639238_2 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001229 267.0
DTH2_k127_4639238_3 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000001354 118.0
DTH2_k127_4660186_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 550.0
DTH2_k127_4660186_1 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 427.0
DTH2_k127_4660186_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 329.0
DTH2_k127_4660186_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000003892 125.0
DTH2_k127_4660186_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000001469 70.0
DTH2_k127_4661732_0 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 305.0
DTH2_k127_4661732_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003985 265.0
DTH2_k127_4661732_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000225 123.0
DTH2_k127_4661732_3 Phospholipid methyltransferase - - - 0.000000000000000001461 94.0
DTH2_k127_4661732_4 - - - - 0.000000000000001284 81.0
DTH2_k127_4665943_0 alpha beta hydrolase fold K03821 - - 7.498e-246 771.0
DTH2_k127_4665943_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 565.0
DTH2_k127_4665943_2 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 540.0
DTH2_k127_4665943_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 460.0
DTH2_k127_4665943_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 321.0
DTH2_k127_4665943_5 Putative regulatory protein - - - 0.00000000000000000000000000001192 121.0
DTH2_k127_4665943_6 Type II secretion system protein B K02451 - - 0.0000000000000000001545 90.0
DTH2_k127_4680272_0 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 415.0
DTH2_k127_4680272_1 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000001504 135.0
DTH2_k127_4680272_2 KR domain - - - 0.0000008834 50.0
DTH2_k127_4694815_0 TonB-dependent receptor K02014 - - 1.041e-216 702.0
DTH2_k127_4694815_1 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 617.0
DTH2_k127_4694815_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000006677 199.0
DTH2_k127_4694815_11 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000001168 192.0
DTH2_k127_4694815_12 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000001954 181.0
DTH2_k127_4694815_13 - - - - 0.0000000000000000000000000000000000000007986 154.0
DTH2_k127_4694815_14 PFAM Metallophosphoesterase - - - 0.0000000000000000000000000000000000000109 163.0
DTH2_k127_4694815_15 PFAM TOBE domain protein - - - 0.000000000000000001779 87.0
DTH2_k127_4694815_2 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 456.0
DTH2_k127_4694815_3 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 385.0
DTH2_k127_4694815_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 367.0
DTH2_k127_4694815_5 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
DTH2_k127_4694815_6 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 291.0
DTH2_k127_4694815_7 Transcriptional regulator of molybdate metabolism, LysR family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
DTH2_k127_4694815_8 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003938 261.0
DTH2_k127_4694815_9 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 262.0
DTH2_k127_4717196_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.808e-273 853.0
DTH2_k127_4717196_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 604.0
DTH2_k127_4717196_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 478.0
DTH2_k127_4717196_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 390.0
DTH2_k127_4717196_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 290.0
DTH2_k127_4717196_5 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000006199 135.0
DTH2_k127_4717196_6 Thioredoxin K05838 - - 0.00000000000000000009335 91.0
DTH2_k127_4719147_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2235.0
DTH2_k127_4719147_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1163.0
DTH2_k127_4719147_2 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 6.239e-212 660.0
DTH2_k127_4719147_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.042e-211 665.0
DTH2_k127_4719147_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 608.0
DTH2_k127_4719147_5 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 575.0
DTH2_k127_4719147_6 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 538.0
DTH2_k127_4719147_7 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 399.0
DTH2_k127_4719147_8 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 328.0
DTH2_k127_4719147_9 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000002936 121.0
DTH2_k127_4727651_0 TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 497.0
DTH2_k127_4727651_1 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 354.0
DTH2_k127_4727651_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
DTH2_k127_4727651_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000001898 78.0
DTH2_k127_4735230_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.426e-208 658.0
DTH2_k127_4735230_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 441.0
DTH2_k127_4739046_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 511.0
DTH2_k127_4739046_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 499.0
DTH2_k127_4739046_2 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 455.0
DTH2_k127_4739046_3 Protein conserved in bacteria - - - 0.0000000005179 67.0
DTH2_k127_4746537_0 Homospermidine synthase K00808 - 2.5.1.44 2.005e-216 684.0
DTH2_k127_4746537_1 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 582.0
DTH2_k127_4746537_10 Cytochrome c - - - 0.00000000001411 68.0
DTH2_k127_4746537_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 364.0
DTH2_k127_4746537_3 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
DTH2_k127_4746537_4 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000001547 213.0
DTH2_k127_4746537_5 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000002472 206.0
DTH2_k127_4746537_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000007422 180.0
DTH2_k127_4746537_7 - - - - 0.000000000000000000000000000000001882 138.0
DTH2_k127_4746537_8 Belongs to the globin family - - - 0.000000000000000000000000008218 117.0
DTH2_k127_4746537_9 Protein of unknown function (DUF3567) - - - 0.00000000001197 68.0
DTH2_k127_4754552_0 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003889 243.0
DTH2_k127_4754552_1 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
DTH2_k127_4754552_2 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000009769 133.0
DTH2_k127_4754552_3 Helix-turn-helix K21498 - - 0.00000000000000000000000000002425 119.0
DTH2_k127_4754552_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000005334 115.0
DTH2_k127_4754552_5 Ni,Fe-hydrogenase I large subunit - - - 0.00000000000000000000001942 107.0
DTH2_k127_4754552_6 Rubredoxin - - - 0.00000000000000000000002218 109.0
DTH2_k127_4754552_7 Hydrogenase-1 expression protein HyaE - - - 0.000000000000000000001898 109.0
DTH2_k127_478645_0 Zinc-binding dehydrogenase K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 511.0
DTH2_k127_478645_1 Aldo keto reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 408.0
DTH2_k127_478645_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 282.0
DTH2_k127_4815101_0 Heavy-metal-associated domain K01533 - 3.6.3.4 1.72e-216 688.0
DTH2_k127_4815101_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 592.0
DTH2_k127_4815101_10 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001089 254.0
DTH2_k127_4815101_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
DTH2_k127_4815101_12 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000009786 190.0
DTH2_k127_4815101_2 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 560.0
DTH2_k127_4815101_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 461.0
DTH2_k127_4815101_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 383.0
DTH2_k127_4815101_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 323.0
DTH2_k127_4815101_6 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 304.0
DTH2_k127_4815101_7 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
DTH2_k127_4815101_8 plastoquinol--plastocyanin reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001998 259.0
DTH2_k127_4815101_9 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
DTH2_k127_4822160_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 490.0
DTH2_k127_4822160_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000002775 53.0
DTH2_k127_4826732_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 502.0
DTH2_k127_4826732_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 419.0
DTH2_k127_4826732_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 353.0
DTH2_k127_4826732_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 331.0
DTH2_k127_4826732_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006707 280.0
DTH2_k127_4826732_5 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000000000298 152.0
DTH2_k127_4858078_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1008.0
DTH2_k127_4858078_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
DTH2_k127_4858078_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 323.0
DTH2_k127_4858078_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000007479 254.0
DTH2_k127_4858078_4 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000244 273.0
DTH2_k127_4858078_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
DTH2_k127_4858078_6 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000007245 182.0
DTH2_k127_4858078_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000005553 152.0
DTH2_k127_4858078_8 Tetratricopeptide repeat K02200 - - 0.00000000000000001698 91.0
DTH2_k127_4858078_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000004456 77.0
DTH2_k127_4872577_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 578.0
DTH2_k127_4872577_1 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 320.0
DTH2_k127_4872577_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000005005 196.0
DTH2_k127_4872577_3 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000002408 187.0
DTH2_k127_4872577_4 TIGRFAM TonB family protein K03646 - - 0.000000000000000000000000000000000000000000001261 181.0
DTH2_k127_4872577_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000001246 162.0
DTH2_k127_4872577_6 4-hydroxybenzoyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000001434 164.0
DTH2_k127_4872577_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000001967 92.0
DTH2_k127_4883615_0 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 347.0
DTH2_k127_4883615_1 - - - - 0.000000000000000000000000000002873 131.0
DTH2_k127_4883615_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0008835 45.0
DTH2_k127_4896755_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 378.0
DTH2_k127_4896755_1 Transposase IS66 family - - - 0.00000000000000000000006207 112.0
DTH2_k127_4898300_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0 1186.0
DTH2_k127_4898300_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 437.0
DTH2_k127_4898300_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
DTH2_k127_4898300_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000000008089 215.0
DTH2_k127_4898300_4 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000005045 203.0
DTH2_k127_4898300_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000001026 178.0
DTH2_k127_4949147_0 ABC transporter transmembrane region K06147 - - 2.927e-303 938.0
DTH2_k127_4949147_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 1.138e-194 611.0
DTH2_k127_4949147_10 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 307.0
DTH2_k127_4949147_11 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000244 205.0
DTH2_k127_4949147_12 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000006976 194.0
DTH2_k127_4949147_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000001761 116.0
DTH2_k127_4949147_14 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000001265 51.0
DTH2_k127_4949147_2 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 606.0
DTH2_k127_4949147_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 456.0
DTH2_k127_4949147_4 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 452.0
DTH2_k127_4949147_5 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
DTH2_k127_4949147_6 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 377.0
DTH2_k127_4949147_7 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 352.0
DTH2_k127_4949147_8 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 346.0
DTH2_k127_4949147_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
DTH2_k127_4952958_0 PFAM multicopper oxidase type 2 K22350 - 1.16.3.3 2.12e-321 1020.0
DTH2_k127_4952958_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 3.487e-195 620.0
DTH2_k127_4952958_2 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 490.0
DTH2_k127_4952958_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 408.0
DTH2_k127_4952958_4 SCO1 SenC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 356.0
DTH2_k127_4952958_5 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
DTH2_k127_4952958_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001519 266.0
DTH2_k127_4952958_7 COG0790 FOG TPR repeat, SEL1 subfamily K07126 GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564 - 0.00000000000000000000000000000000000000000000000000000001552 209.0
DTH2_k127_4952958_8 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.0000000000000000000000000000943 136.0
DTH2_k127_4952958_9 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000005053 102.0
DTH2_k127_4968258_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 1.038e-203 640.0
DTH2_k127_4968258_1 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
DTH2_k127_4968258_2 DUF167 K09131 - - 0.00000000000000000000000006413 110.0
DTH2_k127_4968258_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000007944 60.0
DTH2_k127_5008671_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 595.0
DTH2_k127_5027157_0 Soluble lytic murein transglycosylase L domain K08309 - - 2.259e-227 722.0
DTH2_k127_5027157_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 589.0
DTH2_k127_5027157_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 362.0
DTH2_k127_5027157_3 - - - - 0.000000000000000000000000000000000000000000000000000003507 197.0
DTH2_k127_5035614_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 494.0
DTH2_k127_5035614_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 412.0
DTH2_k127_5035614_2 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 387.0
DTH2_k127_5035614_3 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000001636 208.0
DTH2_k127_5035614_4 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000002407 112.0
DTH2_k127_5035614_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000124 58.0
DTH2_k127_5092400_0 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 374.0
DTH2_k127_5092400_1 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000003272 172.0
DTH2_k127_5092400_2 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000001369 176.0
DTH2_k127_5092400_3 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000106 117.0
DTH2_k127_5096117_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.141e-204 644.0
DTH2_k127_5096117_1 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 411.0
DTH2_k127_5096117_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001453 276.0
DTH2_k127_5096117_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
DTH2_k127_5096117_4 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000005964 213.0
DTH2_k127_5187036_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.887e-202 640.0
DTH2_k127_5187036_1 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 489.0
DTH2_k127_5187036_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 329.0
DTH2_k127_5187036_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000003031 151.0
DTH2_k127_5200278_0 Ammonium Transporter K03320 - - 2.224e-218 685.0
DTH2_k127_5200278_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 4.97e-217 680.0
DTH2_k127_5200278_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 427.0
DTH2_k127_5200278_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000004429 89.0
DTH2_k127_5214669_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1660.0
DTH2_k127_5214669_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000002133 259.0
DTH2_k127_5214669_2 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000000000000000000006366 159.0
DTH2_k127_5214669_3 RNA-binding protein containing KH domain possibly ribosomal protein - - - 0.000000000000000000000000003221 116.0
DTH2_k127_5214669_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000002298 88.0
DTH2_k127_5221310_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 608.0
DTH2_k127_5221310_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 582.0
DTH2_k127_5221310_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000005387 178.0
DTH2_k127_5221310_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000008933 132.0
DTH2_k127_5221310_2 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 578.0
DTH2_k127_5221310_3 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 543.0
DTH2_k127_5221310_4 FAD linked oxidases, C-terminal domain K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 543.0
DTH2_k127_5221310_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 527.0
DTH2_k127_5221310_6 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 487.0
DTH2_k127_5221310_7 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 467.0
DTH2_k127_5221310_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 345.0
DTH2_k127_5221310_9 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 334.0
DTH2_k127_5234638_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 540.0
DTH2_k127_5234638_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
DTH2_k127_5234638_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
DTH2_k127_5234638_3 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000000002158 135.0
DTH2_k127_5275350_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2561.0
DTH2_k127_5275350_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 509.0
DTH2_k127_5275350_2 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 354.0
DTH2_k127_5275350_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000055 292.0
DTH2_k127_5275350_4 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004964 242.0
DTH2_k127_5275350_5 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000004911 192.0
DTH2_k127_5275350_6 MazG-like family - - - 0.0000000000000000000000000000000002918 136.0
DTH2_k127_5275350_7 Protein of unknown function (DUF465) K09794 - - 0.000000006148 63.0
DTH2_k127_5275350_8 GDSL-like Lipase/Acylhydrolase family - - - 0.0001116 51.0
DTH2_k127_5275720_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 310.0
DTH2_k127_5275720_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 305.0
DTH2_k127_5362663_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.357e-251 783.0
DTH2_k127_5362663_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 512.0
DTH2_k127_5362663_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 450.0
DTH2_k127_5362663_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000004212 242.0
DTH2_k127_5362663_4 Tetratricopeptide repeat K02656 - - 0.0000000000000000000000000000000000000000000000000009444 205.0
DTH2_k127_5362663_5 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000008138 171.0
DTH2_k127_5362663_6 Transcriptional regulator K15539 - - 0.00000000000000008332 93.0
DTH2_k127_5372073_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1137.0
DTH2_k127_5372073_1 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 292.0
DTH2_k127_5383465_0 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 382.0
DTH2_k127_5383465_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000002771 154.0
DTH2_k127_5383465_2 Cytochrome c - - - 0.00000000000000000000000000003808 132.0
DTH2_k127_5383465_3 PQQ-like domain - - - 0.0000000000000000000000000005023 113.0
DTH2_k127_5383465_4 Trypsin-like peptidase domain - - - 0.000000155 64.0
DTH2_k127_5429096_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0 1469.0
DTH2_k127_5429096_1 cytochrome - - - 1.679e-254 795.0
DTH2_k127_5429096_10 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000001025 144.0
DTH2_k127_5429096_11 blue (type 1) copper - - - 0.0000000000000000000000000000001629 128.0
DTH2_k127_5429096_12 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000000000000233 124.0
DTH2_k127_5429096_13 negative regulation of establishment of protein localization K02570 - - 0.000000000000000001812 89.0
DTH2_k127_5429096_2 4Fe-4S single cluster domain - - - 8.715e-226 703.0
DTH2_k127_5429096_3 cytochrome d1, heme region K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 577.0
DTH2_k127_5429096_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 565.0
DTH2_k127_5429096_5 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 451.0
DTH2_k127_5429096_6 4Fe-4S dicluster domain K02573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 407.0
DTH2_k127_5429096_7 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 349.0
DTH2_k127_5429096_8 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
DTH2_k127_5429096_9 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000003418 196.0
DTH2_k127_5444775_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 2.137e-242 755.0
DTH2_k127_5444775_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 7.482e-229 712.0
DTH2_k127_5444775_10 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000002913 173.0
DTH2_k127_5444775_11 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000003224 168.0
DTH2_k127_5444775_12 MaoC like domain - - - 0.000000000000000000000000000000000000000009355 171.0
DTH2_k127_5444775_13 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000003609 152.0
DTH2_k127_5444775_14 KTSC domain - - - 0.000000000000000009446 85.0
DTH2_k127_5444775_15 dehydratase K01724 - 4.2.1.96 0.00001629 48.0
DTH2_k127_5444775_2 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 438.0
DTH2_k127_5444775_3 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 342.0
DTH2_k127_5444775_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
DTH2_k127_5444775_5 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 315.0
DTH2_k127_5444775_6 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
DTH2_k127_5444775_7 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 297.0
DTH2_k127_5444775_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004952 262.0
DTH2_k127_5444775_9 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000006998 199.0
DTH2_k127_5445283_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 613.0
DTH2_k127_5445283_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 517.0
DTH2_k127_5445283_2 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 491.0
DTH2_k127_5445283_3 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 463.0
DTH2_k127_5445283_4 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 397.0
DTH2_k127_5445283_5 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
DTH2_k127_5445283_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000003321 248.0
DTH2_k127_5445283_7 Protein of unknown function DUF47 K07220 - - 0.000000000009625 64.0
DTH2_k127_5445283_8 - - - - 0.0000004668 61.0
DTH2_k127_5495700_0 PFAM ROK family protein K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 406.0
DTH2_k127_5495700_1 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 385.0
DTH2_k127_5495700_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006126 297.0
DTH2_k127_5495700_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000006217 235.0
DTH2_k127_5495700_4 Domain of unknown function (DUF1840) - - - 0.0000000000000000000175 94.0
DTH2_k127_5498997_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 2.717e-253 787.0
DTH2_k127_5498997_1 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 427.0
DTH2_k127_5498997_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 331.0
DTH2_k127_5498997_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000005773 214.0
DTH2_k127_5498997_4 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000001041 185.0
DTH2_k127_5498997_5 Transglutaminase/protease-like homologues - - - 0.000001117 52.0
DTH2_k127_5578285_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 563.0
DTH2_k127_5578285_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 444.0
DTH2_k127_5578285_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000004797 107.0
DTH2_k127_5578285_2 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
DTH2_k127_5578285_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
DTH2_k127_5578285_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 333.0
DTH2_k127_5578285_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 306.0
DTH2_k127_5578285_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
DTH2_k127_5578285_7 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000000005727 186.0
DTH2_k127_5578285_8 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000009941 153.0
DTH2_k127_5578285_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000001049 118.0
DTH2_k127_5578529_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 1.244e-213 669.0
DTH2_k127_5578529_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 392.0
DTH2_k127_5578529_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 372.0
DTH2_k127_5578529_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000007845 131.0
DTH2_k127_5578529_4 YEATS family - - - 0.0000000000009003 78.0
DTH2_k127_5588144_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 3.077e-242 758.0
DTH2_k127_5588144_1 Oxaloacetate decarboxylase, gamma chain - - - 0.0002839 44.0
DTH2_k127_5601233_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 6.28e-226 702.0
DTH2_k127_5601233_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 4.192e-200 639.0
DTH2_k127_5601233_2 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 427.0
DTH2_k127_5601233_3 - - - - 0.0000000000001209 78.0
DTH2_k127_5601233_4 - - - - 0.000000000000278 81.0
DTH2_k127_5618307_0 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 448.0
DTH2_k127_5618307_1 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
DTH2_k127_5618307_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000443 233.0
DTH2_k127_5618307_3 - - - - 0.0000000000000000000000000000000000000000000000000000008787 203.0
DTH2_k127_5655741_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.258e-254 792.0
DTH2_k127_5655741_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 421.0
DTH2_k127_5655741_2 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 317.0
DTH2_k127_5655741_3 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000003348 248.0
DTH2_k127_5655741_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000001062 136.0
DTH2_k127_5689863_0 Surface antigen K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 442.0
DTH2_k127_5689863_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 335.0
DTH2_k127_5780839_0 Malic enzyme K00029 - 1.1.1.40 0.0 1077.0
DTH2_k127_5780839_1 elongation factor G K02355 - - 5e-324 1005.0
DTH2_k127_5780839_10 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
DTH2_k127_5780839_11 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
DTH2_k127_5780839_12 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
DTH2_k127_5780839_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000001396 179.0
DTH2_k127_5780839_14 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000002265 153.0
DTH2_k127_5780839_15 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001151 144.0
DTH2_k127_5780839_16 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000008404 145.0
DTH2_k127_5780839_17 - - - - 0.00000000000000000000000000000001337 128.0
DTH2_k127_5780839_18 - - - - 0.000000000000001389 79.0
DTH2_k127_5780839_19 - - - - 0.00000000000001998 80.0
DTH2_k127_5780839_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 4.453e-264 833.0
DTH2_k127_5780839_20 NmrA-like family - - - 0.00005131 46.0
DTH2_k127_5780839_21 Outer membrane lipoprotein K07285 - - 0.0005152 51.0
DTH2_k127_5780839_3 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 538.0
DTH2_k127_5780839_4 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 504.0
DTH2_k127_5780839_5 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 382.0
DTH2_k127_5780839_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
DTH2_k127_5780839_7 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
DTH2_k127_5780839_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 284.0
DTH2_k127_5780839_9 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001437 242.0
DTH2_k127_5912242_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 8.571e-196 621.0
DTH2_k127_5912242_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 432.0
DTH2_k127_5912242_2 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000001161 190.0
DTH2_k127_5931291_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1069.0
DTH2_k127_5931291_1 Type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 529.0
DTH2_k127_5931291_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 469.0
DTH2_k127_5931291_3 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000009305 207.0
DTH2_k127_5931291_4 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000002661 189.0
DTH2_k127_5973243_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 317.0
DTH2_k127_5973243_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 322.0
DTH2_k127_5973243_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000002274 156.0
DTH2_k127_5982368_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 523.0
DTH2_k127_5982368_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000289 229.0
DTH2_k127_5982941_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.384e-261 817.0
DTH2_k127_5982941_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 393.0
DTH2_k127_5982941_2 response regulator K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 306.0
DTH2_k127_5982941_3 Belongs to the peptidase S8 family K13276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007449 260.0
DTH2_k127_6000245_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 444.0
DTH2_k127_6000245_1 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002973 248.0
DTH2_k127_6000245_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000874 226.0
DTH2_k127_6000245_3 Redoxin - - - 0.000000000000000001357 88.0
DTH2_k127_6000245_4 KR domain - - - 0.0000008834 50.0
DTH2_k127_601059_0 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 424.0
DTH2_k127_601059_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 361.0
DTH2_k127_601059_2 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 355.0
DTH2_k127_601059_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003247 293.0
DTH2_k127_601059_4 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 269.0
DTH2_k127_601059_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005068 241.0
DTH2_k127_601059_6 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
DTH2_k127_601059_7 DsrC like protein - - - 0.000000000000000000000000000000000000000009118 156.0
DTH2_k127_601059_8 Rubredoxin - - - 0.000000000000000000000000009988 119.0
DTH2_k127_6110127_0 Pfam Fatty acid - - - 8.414e-262 832.0
DTH2_k127_6110127_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 484.0
DTH2_k127_6110127_2 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 433.0
DTH2_k127_6110127_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 362.0
DTH2_k127_6110127_4 glycosyl transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 327.0
DTH2_k127_6110127_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000003154 208.0
DTH2_k127_6110127_6 - - - - 0.000000000000000000000000000000000001264 150.0
DTH2_k127_6132477_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 552.0
DTH2_k127_6132477_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 295.0
DTH2_k127_6132477_11 Protein of unknown function (DUF2283) - - - 0.00000000000000007997 82.0
DTH2_k127_6132477_12 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000001897 76.0
DTH2_k127_6132477_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000227 237.0
DTH2_k127_6132477_3 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000009928 203.0
DTH2_k127_6132477_4 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000001543 208.0
DTH2_k127_6132477_5 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000671 201.0
DTH2_k127_6132477_6 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000009448 201.0
DTH2_k127_6132477_7 - - - - 0.0000000000000000000000000000000000000000000000000001242 194.0
DTH2_k127_6132477_8 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000001183 182.0
DTH2_k127_6132477_9 nuclease activity - - - 0.000000000000000000000000000000006358 131.0
DTH2_k127_6199971_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.2e-232 738.0
DTH2_k127_6199971_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 586.0
DTH2_k127_6199971_10 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000001303 236.0
DTH2_k127_6199971_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000002402 133.0
DTH2_k127_6199971_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 584.0
DTH2_k127_6199971_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 519.0
DTH2_k127_6199971_4 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 429.0
DTH2_k127_6199971_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 356.0
DTH2_k127_6199971_6 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
DTH2_k127_6199971_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004611 274.0
DTH2_k127_6199971_8 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000216 246.0
DTH2_k127_6199971_9 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000000000000001682 226.0
DTH2_k127_6210196_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.756e-268 831.0
DTH2_k127_6210196_1 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 355.0
DTH2_k127_6210196_10 Protein of unknown function (DUF504) - - - 0.00000000000000000003838 101.0
DTH2_k127_6210196_2 NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 336.0
DTH2_k127_6210196_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 332.0
DTH2_k127_6210196_4 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 341.0
DTH2_k127_6210196_5 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
DTH2_k127_6210196_6 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000007576 234.0
DTH2_k127_6210196_7 maturation - - - 0.0000000000000000000000000000000000000000000009241 171.0
DTH2_k127_6210196_8 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000947 165.0
DTH2_k127_6210196_9 THUMP - - - 0.00000000000000000000000000001156 124.0
DTH2_k127_6217729_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
DTH2_k127_6217729_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 356.0
DTH2_k127_6217729_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 333.0
DTH2_k127_6217729_3 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 318.0
DTH2_k127_6217729_4 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000000002484 111.0
DTH2_k127_6229054_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1760.0
DTH2_k127_6240587_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.207e-283 881.0
DTH2_k127_6240587_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 516.0
DTH2_k127_6240587_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 323.0
DTH2_k127_6240587_3 Biopolymer transport protein K03559 - - 0.00000000002966 64.0
DTH2_k127_6240587_4 - - - - 0.00001386 53.0
DTH2_k127_6254312_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.393e-288 890.0
DTH2_k127_6254312_1 Beta-Casp domain K07576 - - 4.602e-196 627.0
DTH2_k127_6254312_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 573.0
DTH2_k127_6254312_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 479.0
DTH2_k127_6254312_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 411.0
DTH2_k127_6254312_5 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000000009924 201.0
DTH2_k127_6254312_6 membrane - - - 0.0000000000000000000000000000000000000000008664 162.0
DTH2_k127_6254312_7 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000003372 128.0
DTH2_k127_6254312_8 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000004242 125.0
DTH2_k127_6254312_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000135 75.0
DTH2_k127_6320182_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 580.0
DTH2_k127_6320182_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 541.0
DTH2_k127_6320182_10 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000001035 138.0
DTH2_k127_6320182_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 404.0
DTH2_k127_6320182_3 AIR synthase related protein, N-terminal domain K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 379.0
DTH2_k127_6320182_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 340.0
DTH2_k127_6320182_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001775 277.0
DTH2_k127_6320182_6 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001489 261.0
DTH2_k127_6320182_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000003104 230.0
DTH2_k127_6320182_8 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000002476 203.0
DTH2_k127_6320182_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000003943 184.0
DTH2_k127_6327480_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 2.021e-276 866.0
DTH2_k127_6327480_1 Belongs to the glycosyl hydrolase 57 family - - - 7.989e-241 755.0
DTH2_k127_6327480_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000005474 227.0
DTH2_k127_6327480_3 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000001956 189.0
DTH2_k127_6345789_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 494.0
DTH2_k127_6345789_1 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 316.0
DTH2_k127_6345789_2 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007522 244.0
DTH2_k127_6345789_3 - - - - 0.00000000000000000000000000000000000000000000000001011 200.0
DTH2_k127_6345789_4 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000002133 170.0
DTH2_k127_6345789_5 Phasin protein - - - 0.0000000000000000000000000000000000009384 145.0
DTH2_k127_6345789_6 Dioxygenase K03381 - 1.13.11.1 0.0000000000000000000000000004621 120.0
DTH2_k127_6345789_7 Inner membrane protein PRK11099 K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000002468 94.0
DTH2_k127_6345789_8 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000000000006262 66.0
DTH2_k127_6345789_9 Cysteine-rich CWC - - - 0.00000001197 58.0
DTH2_k127_6346801_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.045e-262 830.0
DTH2_k127_6346801_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.461e-254 791.0
DTH2_k127_6346801_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 360.0
DTH2_k127_6346801_11 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007735 247.0
DTH2_k127_6346801_12 Dihydrofolate reductase K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000002668 195.0
DTH2_k127_6346801_13 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001372 139.0
DTH2_k127_6346801_14 TIR domain - - - 0.0000000000000000000000006021 118.0
DTH2_k127_6346801_15 - - - - 0.0000000000007549 70.0
DTH2_k127_6346801_16 pilus assembly protein FimV K08086 - - 0.000001215 53.0
DTH2_k127_6346801_2 Ammonium transporter K03320,K06580 - - 1.045e-216 681.0
DTH2_k127_6346801_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 5.368e-201 631.0
DTH2_k127_6346801_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.252e-194 612.0
DTH2_k127_6346801_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 522.0
DTH2_k127_6346801_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 486.0
DTH2_k127_6346801_7 Major facilitator Superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 466.0
DTH2_k127_6346801_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 453.0
DTH2_k127_6346801_9 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 375.0
DTH2_k127_6356198_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 2.027e-212 673.0
DTH2_k127_6356198_1 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 419.0
DTH2_k127_6356198_2 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0
DTH2_k127_6356198_3 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 350.0
DTH2_k127_6356198_4 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007934 246.0
DTH2_k127_6356198_5 ferredoxin - - - 0.000000000000000000000000000000000000000000000002313 174.0
DTH2_k127_6356198_6 Nitroreductase family - - - 0.0000000000000000004806 89.0
DTH2_k127_6359234_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 546.0
DTH2_k127_6359234_1 D-amino acid dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 488.0
DTH2_k127_6359234_2 pyridine nucleotide-disulfide oxidoreductase family protein K17218 - 1.8.5.4 0.0000000000000000000000000000000000000006406 151.0
DTH2_k127_6373915_0 Domain of unknown function (DUF3400) - - - 0.0 1962.0
DTH2_k127_6373915_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 389.0
DTH2_k127_6373915_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 338.0
DTH2_k127_6373915_3 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000001152 213.0
DTH2_k127_6373915_4 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000001285 177.0
DTH2_k127_6373915_5 membrane - - - 0.000000000000000000000000000000000000000000002503 167.0
DTH2_k127_6415402_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 527.0
DTH2_k127_6415402_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000002287 216.0
DTH2_k127_6415402_2 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000501 134.0
DTH2_k127_6415402_3 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000007236 118.0
DTH2_k127_6437258_0 chain 5 L K00341 - 1.6.5.3 9.971e-300 933.0
DTH2_k127_6437258_1 Molecular chaperone. Has ATPase activity K04079 - - 1.17e-292 912.0
DTH2_k127_6437258_10 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000136 246.0
DTH2_k127_6437258_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000003088 171.0
DTH2_k127_6437258_12 Ribonuclease T2 family - - - 0.00000000000000000000000000000000000000000001353 179.0
DTH2_k127_6437258_13 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000001065 54.0
DTH2_k127_6437258_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.888e-253 789.0
DTH2_k127_6437258_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.682e-204 645.0
DTH2_k127_6437258_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 507.0
DTH2_k127_6437258_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 357.0
DTH2_k127_6437258_6 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 305.0
DTH2_k127_6437258_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 301.0
DTH2_k127_6437258_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004359 272.0
DTH2_k127_6437258_9 Belongs to the enoyl-CoA hydratase isomerase family K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001028 265.0
DTH2_k127_6450151_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.972e-196 620.0
DTH2_k127_6450151_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 440.0
DTH2_k127_6450151_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000002985 66.0
DTH2_k127_6450151_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 422.0
DTH2_k127_6450151_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 400.0
DTH2_k127_6450151_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
DTH2_k127_6450151_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 352.0
DTH2_k127_6450151_6 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
DTH2_k127_6450151_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
DTH2_k127_6450151_8 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000002145 126.0
DTH2_k127_6450151_9 response to antibiotic K07122 - - 0.0000000000000005701 89.0
DTH2_k127_6460096_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1707.0
DTH2_k127_6460096_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1154.0
DTH2_k127_6460096_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 450.0
DTH2_k127_6460096_11 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 402.0
DTH2_k127_6460096_12 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 391.0
DTH2_k127_6460096_13 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 389.0
DTH2_k127_6460096_14 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
DTH2_k127_6460096_15 Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 307.0
DTH2_k127_6460096_16 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
DTH2_k127_6460096_17 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000001016 224.0
DTH2_k127_6460096_18 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000004977 211.0
DTH2_k127_6460096_19 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001362 212.0
DTH2_k127_6460096_2 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 5.47e-298 923.0
DTH2_k127_6460096_20 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000007614 195.0
DTH2_k127_6460096_21 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000000002649 179.0
DTH2_k127_6460096_22 (FHA) domain - - - 0.0000000000000000000000000000000000000001616 151.0
DTH2_k127_6460096_23 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000005587 151.0
DTH2_k127_6460096_24 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000007935 138.0
DTH2_k127_6460096_25 Rhodanese Homology Domain - - - 0.0000000000000000000000000002589 117.0
DTH2_k127_6460096_26 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000003328 110.0
DTH2_k127_6460096_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.913e-295 923.0
DTH2_k127_6460096_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 6.786e-221 734.0
DTH2_k127_6460096_5 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 588.0
DTH2_k127_6460096_6 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 508.0
DTH2_k127_6460096_7 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
DTH2_k127_6460096_8 SMART Elongator protein 3 MiaB NifB K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 493.0
DTH2_k127_6460096_9 lipoate-protein ligase A K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 473.0
DTH2_k127_6461764_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 496.0
DTH2_k127_6461764_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 382.0
DTH2_k127_6461764_2 Major facilitator superfamily - - - 0.0000000000002715 74.0
DTH2_k127_6476188_0 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 265.0
DTH2_k127_6476188_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003369 216.0
DTH2_k127_6476188_2 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000001026 168.0
DTH2_k127_6476188_3 Glycine zipper 2TM domain - - - 0.00000005296 59.0
DTH2_k127_6479_0 SNARE associated Golgi protein - - - 0.0 1042.0
DTH2_k127_6479_1 PFAM ABC transporter K06158 - - 4.335e-225 710.0
DTH2_k127_6479_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 561.0
DTH2_k127_6479_3 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 488.0
DTH2_k127_6479_4 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 326.0
DTH2_k127_6479_5 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009777 273.0
DTH2_k127_6479_6 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0009907 51.0
DTH2_k127_6487752_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 347.0
DTH2_k127_6487752_1 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000008641 256.0
DTH2_k127_6487752_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000002724 121.0
DTH2_k127_6487752_3 Outer membrane lipoprotein K06077 - - 0.00000000000000005013 81.0
DTH2_k127_6488599_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 4.772e-271 864.0
DTH2_k127_6488599_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 602.0
DTH2_k127_6488599_2 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 544.0
DTH2_k127_6488599_3 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 397.0
DTH2_k127_6488599_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 383.0
DTH2_k127_6488599_5 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 344.0
DTH2_k127_6488599_6 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 338.0
DTH2_k127_6488599_7 dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000002909 70.0
DTH2_k127_6516411_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 532.0
DTH2_k127_6516411_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 439.0
DTH2_k127_6516411_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 357.0
DTH2_k127_6516411_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 278.0
DTH2_k127_6516411_4 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
DTH2_k127_6516411_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000007072 171.0
DTH2_k127_6516411_6 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000002155 132.0
DTH2_k127_6520035_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 336.0
DTH2_k127_6520035_1 epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 298.0
DTH2_k127_6520035_2 - - - - 0.00000000000000000000000000000000872 130.0
DTH2_k127_6520035_3 Protein of unknown function (DUF2283) - - - 0.0000000000000000000000001047 107.0
DTH2_k127_6526443_0 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000001087 179.0
DTH2_k127_6526443_1 LysM domain - - - 0.0000000000000000000000000000002461 132.0
DTH2_k127_6529666_0 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000005649 181.0
DTH2_k127_6529666_1 Transcriptional regulatory protein K02483 - - 0.0000000000000000000000000000001921 127.0
DTH2_k127_6529666_2 Cysteine-rich secretory protein family - - - 0.0000000004379 68.0
DTH2_k127_6569912_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 392.0
DTH2_k127_6569912_1 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000177 128.0
DTH2_k127_6569912_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000007453 89.0
DTH2_k127_6575545_0 Bacterial regulatory protein, Fis family K19641 - - 3.856e-211 669.0
DTH2_k127_6575545_1 Nickel-dependent hydrogenase K06281 - 1.12.99.6 4.325e-198 625.0
DTH2_k127_6575545_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K00534 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 511.0
DTH2_k127_6575545_3 - - - - 0.0000000000000000000000000000000000006336 143.0
DTH2_k127_6575545_4 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000002013 112.0
DTH2_k127_6575545_5 Formyl transferase, C-terminal domain K19640 - - 0.000000000000000000000002957 103.0
DTH2_k127_6575545_6 Large subunit K06281 - 1.12.99.6 0.00000000000000004548 82.0
DTH2_k127_6575545_7 PFAM Nickel-dependent hydrogenase, large subunit K06281 - 1.12.99.6 0.0000000000000003374 79.0
DTH2_k127_6575545_8 CBS domain containing protein - - - 0.000004771 55.0
DTH2_k127_6623514_0 PFAM membrane bound O-acyl transferase MBOAT family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 374.0
DTH2_k127_6629923_0 Poly-beta-hydroxybutyrate K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 606.0
DTH2_k127_6629923_1 chemotaxis K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 538.0
DTH2_k127_6629923_2 Histidine kinase K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 390.0
DTH2_k127_6629923_3 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
DTH2_k127_6629923_4 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000002247 198.0
DTH2_k127_6629923_5 PFAM CheW domain protein K02659 - - 0.000000000000000000000000000000000000000000004014 171.0
DTH2_k127_6636304_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 2.743e-221 701.0
DTH2_k127_6636304_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 417.0
DTH2_k127_6636304_2 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000009471 168.0
DTH2_k127_671010_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 4.744e-202 634.0
DTH2_k127_671010_1 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001246 249.0
DTH2_k127_671010_2 - - - - 0.0000000000000000000000000151 111.0
DTH2_k127_6737682_0 Histidine kinase - - - 7.429e-234 745.0
DTH2_k127_6737682_1 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 517.0
DTH2_k127_6737682_10 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000000000000000001326 125.0
DTH2_k127_6737682_11 Thioredoxin-like - - - 0.0000000000000000000000000001015 124.0
DTH2_k127_6737682_12 Putative zinc-finger - - - 0.000000000001084 72.0
DTH2_k127_6737682_13 - - - - 0.00000001124 63.0
DTH2_k127_6737682_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 495.0
DTH2_k127_6737682_3 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 445.0
DTH2_k127_6737682_4 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 267.0
DTH2_k127_6737682_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000003032 278.0
DTH2_k127_6737682_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
DTH2_k127_6737682_7 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000705 196.0
DTH2_k127_6737682_8 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000003854 180.0
DTH2_k127_6737682_9 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000001468 158.0
DTH2_k127_6744109_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1013.0
DTH2_k127_6744109_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.5e-323 997.0
DTH2_k127_6744109_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
DTH2_k127_6744109_3 MnmE helical domain K03650 - - 0.000000000000000000000000000000000186 134.0
DTH2_k127_6744109_4 Planctomycete cytochrome C - - - 0.0000000000000000000000000000001809 128.0
DTH2_k127_6744109_5 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.00000000000000000316 100.0
DTH2_k127_6778951_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 294.0
DTH2_k127_6778951_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000003579 256.0
DTH2_k127_6778951_2 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000599 180.0
DTH2_k127_6778951_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000001176 139.0
DTH2_k127_6778951_4 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000002551 145.0
DTH2_k127_6778951_5 BON domain - - - 0.000000000000000000000006174 109.0
DTH2_k127_6860187_0 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000001482 205.0
DTH2_k127_6883771_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1420.0
DTH2_k127_6883771_1 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 472.0
DTH2_k127_6883771_2 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 355.0
DTH2_k127_6883771_3 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 231.0
DTH2_k127_6883771_4 FecR protein - - - 0.0000000000000000000000000001058 133.0
DTH2_k127_6883771_5 Protein of unknown function (DUF560) - - - 0.00000000000001125 87.0
DTH2_k127_6883771_6 FecR protein - - - 0.000002546 58.0
DTH2_k127_6889402_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 514.0
DTH2_k127_6889402_1 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000001075 234.0
DTH2_k127_6889402_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000682 47.0
DTH2_k127_6999453_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.799e-318 987.0
DTH2_k127_6999453_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 570.0
DTH2_k127_6999453_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004608 251.0
DTH2_k127_7001995_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 6.888e-247 767.0
DTH2_k127_7001995_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000008031 149.0
DTH2_k127_7008549_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 409.0
DTH2_k127_7008549_1 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.000000000000000000000000000000000000000000000000000000000003922 210.0
DTH2_k127_7008549_2 Major facilitator Superfamily - - - 0.0000000000000006035 88.0
DTH2_k127_7029697_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 4.245e-275 860.0
DTH2_k127_7029697_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 479.0
DTH2_k127_7029697_10 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000009583 112.0
DTH2_k127_7029697_11 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000003336 108.0
DTH2_k127_7029697_12 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.00000000000002433 76.0
DTH2_k127_7029697_13 Fe-S protein K06938 - - 0.00000000004691 66.0
DTH2_k127_7029697_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 459.0
DTH2_k127_7029697_3 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 438.0
DTH2_k127_7029697_4 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 382.0
DTH2_k127_7029697_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003005 235.0
DTH2_k127_7029697_6 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000001157 168.0
DTH2_k127_7029697_7 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000000005207 164.0
DTH2_k127_7029697_8 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000008235 150.0
DTH2_k127_7029697_9 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000001391 143.0
DTH2_k127_704796_0 O-acetylhomoserine K01740 - 2.5.1.49 1.159e-230 719.0
DTH2_k127_704796_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 539.0
DTH2_k127_704796_2 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 502.0
DTH2_k127_704796_3 surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 438.0
DTH2_k127_704796_4 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001009 275.0
DTH2_k127_704796_6 Domain of unknown function (DUF4936) - - - 0.0000000000008573 77.0
DTH2_k127_704982_0 alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.028e-214 703.0
DTH2_k127_704982_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001039 304.0
DTH2_k127_7056855_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 328.0
DTH2_k127_7056855_1 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 287.0
DTH2_k127_7056855_2 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000006588 184.0
DTH2_k127_7056855_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000003335 136.0
DTH2_k127_7065908_0 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 599.0
DTH2_k127_7065908_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 548.0
DTH2_k127_7065908_10 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 289.0
DTH2_k127_7065908_11 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001969 270.0
DTH2_k127_7065908_12 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000007515 247.0
DTH2_k127_7065908_13 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
DTH2_k127_7065908_14 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000001565 121.0
DTH2_k127_7065908_15 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000001162 115.0
DTH2_k127_7065908_16 ThiS family K03154 - - 0.000000000000000000002249 95.0
DTH2_k127_7065908_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 541.0
DTH2_k127_7065908_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 445.0
DTH2_k127_7065908_4 a g-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 439.0
DTH2_k127_7065908_5 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 425.0
DTH2_k127_7065908_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 365.0
DTH2_k127_7065908_7 Thioredoxin-like K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 343.0
DTH2_k127_7065908_8 Putative methyltransferase K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 336.0
DTH2_k127_7065908_9 Formaldehyde-activating enzyme (Fae) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
DTH2_k127_7066332_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 367.0
DTH2_k127_7066332_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 352.0
DTH2_k127_7100117_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1301.0
DTH2_k127_7100117_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.286e-239 741.0
DTH2_k127_7100117_2 DNA polymerase III K02342 - 2.7.7.7 6.528e-239 758.0
DTH2_k127_7100117_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 5.21e-205 686.0
DTH2_k127_7100117_4 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 357.0
DTH2_k127_7100117_5 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000008179 175.0
DTH2_k127_7100117_6 - - - - 0.000000000000001895 78.0
DTH2_k127_7112839_0 Outer membrane protein beta-barrel family - - - 6.775e-275 873.0
DTH2_k127_7112839_1 - - - - 0.000000000000000000000000000000000000000003278 170.0
DTH2_k127_7112839_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000003409 154.0
DTH2_k127_7219027_0 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 508.0
DTH2_k127_7219027_1 Tetratricopeptide repeat - - - 0.000000000007087 78.0
DTH2_k127_7296588_0 Transport Permease Protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009233 284.0
DTH2_k127_7296588_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000116 248.0
DTH2_k127_7296588_2 Phasin protein - - - 0.000000000000000000000000000000000002402 145.0
DTH2_k127_7296588_3 pfam abc K01990 - - 0.0000000000000007631 80.0
DTH2_k127_729745_0 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 3.039e-246 767.0
DTH2_k127_729745_1 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 406.0
DTH2_k127_7300529_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 535.0
DTH2_k127_7300529_1 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 506.0
DTH2_k127_7300529_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 372.0
DTH2_k127_7300529_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004059 257.0
DTH2_k127_7300529_4 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000001788 152.0
DTH2_k127_7340485_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.723e-251 780.0
DTH2_k127_7340485_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 4.094e-218 685.0
DTH2_k127_7340485_10 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000009555 133.0
DTH2_k127_7340485_11 membrane K06077 - - 0.00000000000000002177 85.0
DTH2_k127_7340485_2 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 564.0
DTH2_k127_7340485_3 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 490.0
DTH2_k127_7340485_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 495.0
DTH2_k127_7340485_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 309.0
DTH2_k127_7340485_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
DTH2_k127_7340485_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000005051 192.0
DTH2_k127_7340485_8 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000002016 177.0
DTH2_k127_7340485_9 HNH nucleases - - - 0.00000000000000000000000000000000000000000000001097 177.0
DTH2_k127_7382797_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.043e-214 673.0
DTH2_k127_7382797_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.411e-207 662.0
DTH2_k127_7382797_2 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000004994 199.0
DTH2_k127_7382797_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000008238 132.0
DTH2_k127_7382797_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000002113 124.0
DTH2_k127_7411704_0 Signal transduction histidine kinase - - - 5.59e-233 743.0
DTH2_k127_7411704_1 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000003153 186.0
DTH2_k127_743959_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 571.0
DTH2_k127_743959_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 526.0
DTH2_k127_743959_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
DTH2_k127_743959_3 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000002148 172.0
DTH2_k127_743959_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000002033 160.0
DTH2_k127_743959_5 CNP1-like family - - - 0.0000000000000000000000000000000000000001438 161.0
DTH2_k127_743959_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000002024 141.0
DTH2_k127_743959_7 Protein of unknown function (DUF3617) - - - 0.0000000000000004357 92.0
DTH2_k127_743959_8 - - - - 0.000001761 53.0
DTH2_k127_7456526_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.476e-217 681.0
DTH2_k127_7456526_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 304.0
DTH2_k127_7456526_2 - - - - 0.000000000000000000000000000000003408 133.0
DTH2_k127_7456526_3 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000008747 137.0
DTH2_k127_7456526_4 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000221 49.0
DTH2_k127_7458870_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 461.0
DTH2_k127_7458870_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 349.0
DTH2_k127_7458870_2 formaldehyde-activating enzyme K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 289.0
DTH2_k127_7458870_3 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000002561 245.0
DTH2_k127_7458870_4 ATP-grasp domain - - - 0.00000000007037 64.0
DTH2_k127_7462713_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 4.707e-218 691.0
DTH2_k127_7462713_1 - - - - 0.0000000000000000003428 91.0
DTH2_k127_747360_0 UvrD REP K03657 - 3.6.4.12 0.0 1011.0
DTH2_k127_747360_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 7.289e-195 612.0
DTH2_k127_747360_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 480.0
DTH2_k127_747360_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 395.0
DTH2_k127_747360_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
DTH2_k127_747360_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 361.0
DTH2_k127_747360_6 - - - - 0.0000000000000000000000000000000000000000004858 167.0
DTH2_k127_747360_7 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000001875 118.0
DTH2_k127_7477384_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 2.347e-195 623.0
DTH2_k127_7477384_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 509.0
DTH2_k127_7477384_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 348.0
DTH2_k127_7477384_3 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000096 288.0
DTH2_k127_7487270_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 1.842e-285 887.0
DTH2_k127_7487270_1 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 504.0
DTH2_k127_7487270_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 335.0
DTH2_k127_7487270_3 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000127 184.0
DTH2_k127_7487270_4 - - - - 0.00000000000000000002138 107.0
DTH2_k127_7487270_5 - - - - 0.00000005524 64.0
DTH2_k127_7493707_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 547.0
DTH2_k127_7493707_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 329.0
DTH2_k127_7530234_0 Male sterility - - - 5.132e-284 887.0
DTH2_k127_7530234_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.974e-241 757.0
DTH2_k127_7530234_10 - - - - 0.000001937 61.0
DTH2_k127_7530234_2 Belongs to the GMC oxidoreductase family - - - 1.037e-198 634.0
DTH2_k127_7530234_3 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 542.0
DTH2_k127_7530234_4 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 443.0
DTH2_k127_7530234_5 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
DTH2_k127_7530234_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006018 258.0
DTH2_k127_7530234_7 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000004946 190.0
DTH2_k127_7530234_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000001085 150.0
DTH2_k127_7530234_9 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000003032 136.0
DTH2_k127_7531074_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 5.002e-206 649.0
DTH2_k127_7531074_1 synthetase, class II (G H P K01892 - 6.1.1.21 4.67e-197 622.0
DTH2_k127_7531074_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 611.0
DTH2_k127_7531074_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 517.0
DTH2_k127_7531074_4 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 507.0
DTH2_k127_7531074_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 430.0
DTH2_k127_7531074_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000005914 237.0
DTH2_k127_7531074_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000011 142.0
DTH2_k127_7531074_8 Transcriptional regulator K15539 - - 0.000000000000000000001678 96.0
DTH2_k127_7544589_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
DTH2_k127_7544589_1 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 265.0
DTH2_k127_7544589_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000001232 181.0
DTH2_k127_7544589_3 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000007456 121.0
DTH2_k127_7576369_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 567.0
DTH2_k127_7576369_1 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 409.0
DTH2_k127_7576369_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 369.0
DTH2_k127_7576369_3 RDD family - - - 0.000000000000000000000000000000001865 133.0
DTH2_k127_7588704_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1037.0
DTH2_k127_7588704_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.107e-301 928.0
DTH2_k127_7588704_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006413 268.0
DTH2_k127_7588704_2 4Fe-4S dicluster domain K18930 - - 3.213e-277 891.0
DTH2_k127_7588704_3 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 2.716e-220 690.0
DTH2_k127_7588704_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 576.0
DTH2_k127_7588704_5 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 454.0
DTH2_k127_7588704_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 410.0
DTH2_k127_7588704_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 383.0
DTH2_k127_7588704_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 360.0
DTH2_k127_7588704_9 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 296.0
DTH2_k127_7609032_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1190.0
DTH2_k127_7609032_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000004147 202.0
DTH2_k127_7609032_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000002345 188.0
DTH2_k127_7613364_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 492.0
DTH2_k127_7613364_1 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 484.0
DTH2_k127_7613364_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000002815 125.0
DTH2_k127_7613976_0 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 583.0
DTH2_k127_7613976_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 448.0
DTH2_k127_7613976_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 445.0
DTH2_k127_7613976_3 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 362.0
DTH2_k127_7613976_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 306.0
DTH2_k127_7613976_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000005469 230.0
DTH2_k127_7620265_0 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000386 281.0
DTH2_k127_7620265_1 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000001446 154.0
DTH2_k127_7620265_2 Protein involved in electron carrier activity, oxidoreductase activity, protein disulfide oxidoreductase activity, cell redox homeostasis and glycerol ether metabolic process - - - 0.0000000000000000000000000004797 120.0
DTH2_k127_7620265_3 PFAM Cytochrome c assembly protein - - - 0.0000000000000000003326 100.0
DTH2_k127_762856_0 ribonuclease II K01147 - 3.1.13.1 2.444e-251 789.0
DTH2_k127_762856_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 6.723e-249 774.0
DTH2_k127_762856_10 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000003239 207.0
DTH2_k127_762856_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001714 157.0
DTH2_k127_762856_12 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000004022 148.0
DTH2_k127_762856_13 Protein of unknown function (DUF3568) - - - 0.000000000000000000000001614 111.0
DTH2_k127_762856_14 PFAM cytochrome c - - - 0.000000000000000000003969 98.0
DTH2_k127_762856_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 9.432e-223 697.0
DTH2_k127_762856_3 Acts as a magnesium transporter K06213 - - 2.61e-210 663.0
DTH2_k127_762856_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 358.0
DTH2_k127_762856_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 344.0
DTH2_k127_762856_6 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 319.0
DTH2_k127_762856_7 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
DTH2_k127_762856_8 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000005506 213.0
DTH2_k127_762856_9 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000001234 195.0
DTH2_k127_7660075_0 24 kD subunit K00122 - 1.17.1.9 2.789e-276 859.0
DTH2_k127_7660075_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.821e-214 671.0
DTH2_k127_7660075_2 PFAM ATPase associated with various cellular activities, AAA_3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 480.0
DTH2_k127_7660075_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
DTH2_k127_7660075_4 Sulphur oxidation protein SoxZ K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 348.0
DTH2_k127_7660075_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000005722 233.0
DTH2_k127_7660075_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000003338 133.0
DTH2_k127_7660075_7 - - - - 0.0000000000000000000000001637 115.0
DTH2_k127_7660075_8 Protein of unknown function DUF58 - - - 0.000006727 48.0
DTH2_k127_7692198_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 591.0
DTH2_k127_7692198_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 570.0
DTH2_k127_7692198_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 426.0
DTH2_k127_7692198_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 337.0
DTH2_k127_7692198_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
DTH2_k127_7692198_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 300.0
DTH2_k127_7703696_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 411.0
DTH2_k127_7703696_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 327.0
DTH2_k127_7703696_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 289.0
DTH2_k127_7703696_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
DTH2_k127_7703696_4 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000006489 192.0
DTH2_k127_7703696_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000005463 171.0
DTH2_k127_7708127_0 Transcriptional regulator, Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
DTH2_k127_7708127_1 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006963 273.0
DTH2_k127_7708127_2 His Kinase A (phosphoacceptor) domain - - - 0.0000005297 56.0
DTH2_k127_7736266_0 FAD binding domain K00394 - 1.8.99.2 0.0 1260.0
DTH2_k127_7736266_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.728e-220 688.0
DTH2_k127_7736266_2 PFAM AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
DTH2_k127_7736266_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
DTH2_k127_7736266_4 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 308.0
DTH2_k127_7736266_5 PFAM von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000006217 169.0
DTH2_k127_7739379_0 Sulfate transporter antisigma-factor antagonist STAS - - - 6.065e-299 932.0
DTH2_k127_7739379_1 STAS domain K03321 - - 1.505e-231 733.0
DTH2_k127_7739379_10 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001151 213.0
DTH2_k127_7739379_11 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000000000000005645 205.0
DTH2_k127_7739379_12 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000000000000000000000000000002384 201.0
DTH2_k127_7739379_13 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000438 123.0
DTH2_k127_7739379_14 Ethylbenzene dehydrogenase - - - 0.0000000000000000000004384 107.0
DTH2_k127_7739379_15 PFAM GUN4 domain protein - - - 0.0000002421 59.0
DTH2_k127_7739379_16 Protein tyrosine kinase - - - 0.0001255 52.0
DTH2_k127_7739379_2 Chromate K07240 - - 5.172e-200 636.0
DTH2_k127_7739379_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 610.0
DTH2_k127_7739379_4 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 567.0
DTH2_k127_7739379_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 433.0
DTH2_k127_7739379_6 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 326.0
DTH2_k127_7739379_7 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 296.0
DTH2_k127_7739379_8 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007116 238.0
DTH2_k127_7739379_9 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
DTH2_k127_7744762_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 1.775e-228 722.0
DTH2_k127_7744762_1 UDP binding domain K00012 - 1.1.1.22 6.942e-200 632.0
DTH2_k127_7744762_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 583.0
DTH2_k127_7744762_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 310.0
DTH2_k127_780636_0 Belongs to the peptidase S8 family - - - 7.676e-208 655.0
DTH2_k127_780636_1 Sigma-54 interaction domain - - - 2.993e-203 653.0
DTH2_k127_780636_2 PFAM EAL domain, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 553.0
DTH2_k127_780636_3 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 546.0
DTH2_k127_780636_4 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
DTH2_k127_780636_5 Flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004378 244.0
DTH2_k127_7875459_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 4.009e-194 616.0
DTH2_k127_7875459_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 550.0
DTH2_k127_7875459_2 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 486.0
DTH2_k127_7875459_3 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 433.0
DTH2_k127_7875459_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 371.0
DTH2_k127_7875459_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 340.0
DTH2_k127_7875459_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 306.0
DTH2_k127_7875459_7 response regulator - - - 0.0000000000000000001348 94.0
DTH2_k127_79019_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.42e-302 939.0
DTH2_k127_79019_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 535.0
DTH2_k127_79019_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000003681 190.0
DTH2_k127_79019_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000008079 165.0
DTH2_k127_79019_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000006989 164.0
DTH2_k127_79019_5 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000000000004952 88.0
DTH2_k127_7934274_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 7.078e-207 650.0
DTH2_k127_7934274_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 445.0
DTH2_k127_7934274_2 Glycine zipper - - - 0.00000000000000000000000000000000000000000000000000000003133 203.0
DTH2_k127_7934274_3 - - - - 0.0000000000000000002208 87.0
DTH2_k127_7947974_0 Esterase of the alpha-beta hydrolase superfamily - - - 5.597e-232 747.0
DTH2_k127_7947974_1 Tetratricopeptide repeat - - - 7.199e-204 646.0
DTH2_k127_7947974_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001376 224.0
DTH2_k127_7947974_3 - - - - 0.000000000000000000000000001036 125.0
DTH2_k127_7947974_4 transcriptional regulator, SARP family - - - 0.000002324 59.0
DTH2_k127_7947974_5 - - - - 0.00003834 49.0
DTH2_k127_7947974_6 TIR domain - - - 0.00009022 54.0
DTH2_k127_7947999_0 polyphosphate kinase - - - 3.911e-230 722.0
DTH2_k127_7947999_1 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000004968 176.0
DTH2_k127_7947999_2 CHAD - - - 0.000000000000000000000002029 108.0
DTH2_k127_7951137_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1069.0
DTH2_k127_7951137_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 422.0
DTH2_k127_7951137_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 351.0
DTH2_k127_7951137_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000002199 263.0
DTH2_k127_7959069_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1116.0
DTH2_k127_7959069_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.642e-296 913.0
DTH2_k127_7959069_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 557.0
DTH2_k127_7959069_3 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 373.0
DTH2_k127_7959069_4 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000002106 107.0
DTH2_k127_79616_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 511.0
DTH2_k127_79616_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 486.0
DTH2_k127_79616_2 amino acid ABC transporter K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 476.0
DTH2_k127_79616_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 392.0
DTH2_k127_79616_4 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
DTH2_k127_79616_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
DTH2_k127_79616_6 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 287.0
DTH2_k127_79616_7 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000003237 134.0
DTH2_k127_79616_8 FAD binding domain - - - 0.0000000000000000000000002683 121.0
DTH2_k127_796429_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 454.0
DTH2_k127_796429_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 323.0
DTH2_k127_796429_2 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004832 256.0
DTH2_k127_796429_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000000000000000004052 134.0
DTH2_k127_796429_4 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000002447 132.0
DTH2_k127_798964_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 480.0
DTH2_k127_798964_1 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002145 248.0
DTH2_k127_798964_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000001488 186.0
DTH2_k127_798964_3 - - - - 0.00000000000001792 81.0
DTH2_k127_8010942_0 Competence protein ComEC Rec2 K02238 - - 4.618e-290 916.0
DTH2_k127_8010942_1 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000007231 224.0
DTH2_k127_8010942_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000003646 199.0
DTH2_k127_8010942_3 Phosphopantetheine attachment site - - - 0.00000000000000000000001094 102.0
DTH2_k127_8078517_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1395.0
DTH2_k127_8078517_1 Neisseria PilC beta-propeller domain K02674 - - 0.0 1067.0
DTH2_k127_8078517_10 - - - - 0.000000000000000000000000000000000000000001246 167.0
DTH2_k127_8078517_11 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000004284 175.0
DTH2_k127_8078517_12 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000001109 143.0
DTH2_k127_8078517_13 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000000004627 139.0
DTH2_k127_8078517_14 CBS domain - - - 0.0000000000000000000000000000002324 134.0
DTH2_k127_8078517_15 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.0000000000000000000000000000006386 126.0
DTH2_k127_8078517_16 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000000001849 126.0
DTH2_k127_8078517_17 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000005082 113.0
DTH2_k127_8078517_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 602.0
DTH2_k127_8078517_3 Major facilitator Superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 602.0
DTH2_k127_8078517_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 481.0
DTH2_k127_8078517_5 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 475.0
DTH2_k127_8078517_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 444.0
DTH2_k127_8078517_7 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 302.0
DTH2_k127_8078517_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000041 194.0
DTH2_k127_8078517_9 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000004183 182.0
DTH2_k127_8140198_0 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 317.0
DTH2_k127_8140198_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004012 278.0
DTH2_k127_81422_0 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 334.0
DTH2_k127_81422_1 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
DTH2_k127_81422_2 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000001946 220.0
DTH2_k127_81422_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000002542 197.0
DTH2_k127_81422_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001451 173.0
DTH2_k127_81422_5 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000003377 157.0
DTH2_k127_816949_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.437e-208 653.0
DTH2_k127_816949_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 497.0
DTH2_k127_816949_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 465.0
DTH2_k127_816949_3 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 387.0
DTH2_k127_816949_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000001086 57.0
DTH2_k127_817857_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 409.0
DTH2_k127_817857_1 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 365.0
DTH2_k127_817857_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 312.0
DTH2_k127_817857_3 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000192 280.0
DTH2_k127_817857_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000008918 210.0
DTH2_k127_817857_5 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000003606 181.0
DTH2_k127_824798_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 5.31e-229 716.0
DTH2_k127_824798_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
DTH2_k127_824798_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000865 240.0
DTH2_k127_824798_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000001632 132.0
DTH2_k127_8281378_0 His Kinase A (phosphoacceptor) domain K19661 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 543.0
DTH2_k127_8281378_1 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 344.0
DTH2_k127_8281378_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001498 253.0
DTH2_k127_8281378_3 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000004705 205.0
DTH2_k127_8281378_4 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000008544 161.0
DTH2_k127_8281378_5 nitrous oxide reductase K00376 - 1.7.2.4 0.000000001596 60.0
DTH2_k127_8307475_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 8.338e-268 833.0
DTH2_k127_8307475_1 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 409.0
DTH2_k127_8307475_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 391.0
DTH2_k127_8307475_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000001239 147.0
DTH2_k127_837584_0 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 568.0
DTH2_k127_837584_1 Diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 353.0
DTH2_k127_837584_2 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000095 205.0
DTH2_k127_837584_3 Las17-binding protein actin regulator - - - 0.000000000000000001006 93.0
DTH2_k127_837584_4 - - - - 0.00001016 57.0
DTH2_k127_8404768_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000002134 276.0
DTH2_k127_8404768_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000009143 244.0
DTH2_k127_8404768_2 Belongs to the peptidase M48B family - - - 0.000000000000000000000000000000000000000000000000000000003257 212.0
DTH2_k127_8404768_3 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.0000000000000000000000000000000000000000000000000007504 191.0
DTH2_k127_8404768_4 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000001711 139.0
DTH2_k127_8404768_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000003778 56.0
DTH2_k127_8405574_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1023.0
DTH2_k127_8405574_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.407e-265 832.0
DTH2_k127_8405574_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
DTH2_k127_8405574_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008031 267.0
DTH2_k127_8405574_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005104 253.0
DTH2_k127_8405574_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000002918 163.0
DTH2_k127_8405574_14 protein conserved in bacteria - - - 0.0000000000000000000000000002291 121.0
DTH2_k127_8405574_15 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000001257 115.0
DTH2_k127_8405574_16 Domain of unknown function (DUF4845) - - - 0.000000000000000000003672 100.0
DTH2_k127_8405574_17 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.000000000000000000004211 96.0
DTH2_k127_8405574_2 ABC transporter - - - 9.293e-250 777.0
DTH2_k127_8405574_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.092e-204 648.0
DTH2_k127_8405574_4 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 537.0
DTH2_k127_8405574_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
DTH2_k127_8405574_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 389.0
DTH2_k127_8405574_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 353.0
DTH2_k127_8405574_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 295.0
DTH2_k127_8405574_9 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 293.0
DTH2_k127_8422007_0 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 323.0
DTH2_k127_8422007_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
DTH2_k127_8422007_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000002466 84.0
DTH2_k127_8473423_0 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 430.0
DTH2_k127_8473423_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000009207 125.0
DTH2_k127_8473423_2 - - - - 0.000000000000000000002325 100.0
DTH2_k127_8473423_3 - - - - 0.00006775 53.0
DTH2_k127_8497814_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 4.774e-220 706.0
DTH2_k127_8497814_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000174 234.0
DTH2_k127_8497814_2 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000002291 183.0
DTH2_k127_8497814_3 NAD(P)H-binding - - - 0.00000000000000000000000000000000000001194 147.0
DTH2_k127_8497814_4 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000006307 144.0
DTH2_k127_8497814_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000006801 60.0
DTH2_k127_8537640_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1568.0
DTH2_k127_8537640_1 Magnesium transport protein CorA - - - 3.854e-229 721.0
DTH2_k127_8537640_2 Sugar (and other) transporter - - - 5.996e-202 642.0
DTH2_k127_8537640_3 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 536.0
DTH2_k127_8537640_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001688 283.0
DTH2_k127_8537640_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
DTH2_k127_8537640_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000001113 78.0
DTH2_k127_8537640_7 Phosphotransferase enzyme family - - - 0.000212 51.0
DTH2_k127_8541432_0 MMPL family - - - 0.0 1116.0
DTH2_k127_8541432_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 329.0
DTH2_k127_8541432_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000131 208.0
DTH2_k127_854434_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 552.0
DTH2_k127_854434_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 537.0
DTH2_k127_854434_2 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001018 254.0
DTH2_k127_854434_3 - K06950 - - 0.00000000000785 66.0
DTH2_k127_8549198_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1334.0
DTH2_k127_8549198_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 571.0
DTH2_k127_8549198_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 544.0
DTH2_k127_8549198_3 Belongs to the ompA family K03286 - - 0.00000000000003872 76.0
DTH2_k127_8556358_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.232e-217 682.0
DTH2_k127_8556358_1 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 313.0
DTH2_k127_8556358_2 glycosyl - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 296.0
DTH2_k127_8556358_3 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000007831 246.0
DTH2_k127_8556358_4 - - - - 0.0000000000000000000000000000000004636 138.0
DTH2_k127_856100_0 serine threonine protein kinase K12132 - 2.7.11.1 6.171e-311 974.0
DTH2_k127_856100_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 360.0
DTH2_k127_856100_2 (FHA) domain - - - 0.0000000000000000000000000000000000000000000000005909 177.0
DTH2_k127_8573826_0 COG4618 ABC-type protease lipase transport system, ATPase and permease components K16299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 514.0
DTH2_k127_8573826_1 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 443.0
DTH2_k127_8573826_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000283 153.0
DTH2_k127_8573826_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000007289 147.0
DTH2_k127_8573826_4 type I secretion membrane fusion K02022,K12537 - - 0.000000000000000000000000000000008455 133.0
DTH2_k127_8573826_5 positive regulation of growth K07746 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.000000457 55.0
DTH2_k127_859733_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.614e-227 712.0
DTH2_k127_859733_1 Domain of unknown function (DUF4124) - - - 0.0000000000000007687 85.0
DTH2_k127_8599479_0 transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 539.0
DTH2_k127_8599479_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 354.0
DTH2_k127_8599479_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004293 249.0
DTH2_k127_8599479_3 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000502 202.0
DTH2_k127_8599479_4 Polysaccharide deacetylase - - - 0.00000000000000000000002028 101.0
DTH2_k127_861489_0 Large family of predicted nucleotide-binding domains K07175 - - 6.661e-253 785.0
DTH2_k127_861489_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 9.542e-225 704.0
DTH2_k127_861489_10 Ribosomal protein S18 K02963 - - 0.0000000000000000000000000000000004175 133.0
DTH2_k127_861489_11 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000004045 84.0
DTH2_k127_861489_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 493.0
DTH2_k127_861489_3 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 415.0
DTH2_k127_861489_4 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 333.0
DTH2_k127_861489_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 302.0
DTH2_k127_861489_6 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000003806 270.0
DTH2_k127_861489_7 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007663 256.0
DTH2_k127_861489_8 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000004596 211.0
DTH2_k127_861489_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000002067 199.0
DTH2_k127_8622092_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1596.0
DTH2_k127_8622092_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 585.0
DTH2_k127_8622092_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000002171 153.0
DTH2_k127_8643671_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.769e-235 736.0
DTH2_k127_8643671_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 573.0
DTH2_k127_8643671_10 DsrC like protein - - - 0.00000000000000000000000000000000000000002531 157.0
DTH2_k127_8643671_11 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000904 145.0
DTH2_k127_8643671_12 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000003768 109.0
DTH2_k127_8643671_13 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000361 93.0
DTH2_k127_8643671_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
DTH2_k127_8643671_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 284.0
DTH2_k127_8643671_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001805 255.0
DTH2_k127_8643671_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
DTH2_k127_8643671_6 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000007803 189.0
DTH2_k127_8643671_7 Trypsin - - - 0.0000000000000000000000000000000000000000000000004805 193.0
DTH2_k127_8643671_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000001451 164.0
DTH2_k127_8643671_9 - - - - 0.00000000000000000000000000000000000000001651 160.0
DTH2_k127_8649801_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 533.0
DTH2_k127_8649801_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000003955 247.0
DTH2_k127_8649801_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000002367 70.0
DTH2_k127_8653238_0 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000003697 223.0
DTH2_k127_8653238_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000002951 156.0
DTH2_k127_8653238_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000002089 71.0
DTH2_k127_8653238_3 Trypsin-like peptidase domain - - - 0.00000000004947 66.0
DTH2_k127_8690733_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 598.0
DTH2_k127_8696121_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2465.0
DTH2_k127_8696121_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.097e-239 747.0
DTH2_k127_8696121_2 type IV pilus secretin PilQ K02666 - - 2.617e-228 741.0
DTH2_k127_8696121_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 544.0
DTH2_k127_8696121_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 518.0
DTH2_k127_8696121_5 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007554 250.0
DTH2_k127_8696121_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000134 223.0
DTH2_k127_8696121_7 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000002635 180.0
DTH2_k127_8734421_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 519.0
DTH2_k127_8734421_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 530.0
DTH2_k127_8734421_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 480.0
DTH2_k127_8734421_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 357.0
DTH2_k127_8734421_4 4Fe-4S dicluster domain - - - 0.00000000008335 66.0
DTH2_k127_8746496_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 477.0
DTH2_k127_8746496_1 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 394.0
DTH2_k127_8746496_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
DTH2_k127_8746496_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 255.0
DTH2_k127_8746496_4 Universal stress protein family - - - 0.00000000000000000000000000000002717 131.0
DTH2_k127_8746496_5 - - - - 0.00000000000000000000000000000217 136.0
DTH2_k127_8766800_0 Transport of potassium into the cell K03549 - - 1.737e-271 848.0
DTH2_k127_8766800_1 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000053 151.0
DTH2_k127_8768999_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 565.0
DTH2_k127_8768999_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 407.0
DTH2_k127_8768999_2 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 367.0
DTH2_k127_8768999_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000002368 249.0
DTH2_k127_8785741_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 586.0
DTH2_k127_8785741_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000009014 220.0
DTH2_k127_8810351_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 514.0
DTH2_k127_8810351_1 Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine K05396,K17950 - 4.4.1.15,4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 331.0
DTH2_k127_8810351_2 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002276 261.0
DTH2_k127_8810351_3 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000002647 169.0
DTH2_k127_8810351_4 ABC transporter K02028,K10004 - 3.6.3.21 0.000000000000000000000000000000004363 128.0
DTH2_k127_8810351_5 - - - - 0.000000000000004295 84.0
DTH2_k127_882109_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 5.914e-208 676.0
DTH2_k127_882109_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 480.0
DTH2_k127_882109_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
DTH2_k127_882109_3 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
DTH2_k127_882109_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006302 272.0
DTH2_k127_882109_5 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001793 265.0
DTH2_k127_8825703_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
DTH2_k127_8825703_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000001108 205.0
DTH2_k127_8825703_2 - - - - 0.00000000002242 77.0
DTH2_k127_8825703_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00004621 50.0
DTH2_k127_8830245_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 351.0
DTH2_k127_8830245_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 341.0
DTH2_k127_8830245_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 336.0
DTH2_k127_8830245_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003658 267.0
DTH2_k127_8830245_4 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000001836 135.0
DTH2_k127_8830245_5 Heavy metal-associated domain protein K07213 - - 0.00000000000000000001244 93.0
DTH2_k127_8850229_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.129e-238 771.0
DTH2_k127_8850229_1 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 488.0
DTH2_k127_8850229_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000000000006166 179.0
DTH2_k127_8850229_3 Nickel-dependent hydrogenase - - - 0.00000000000000000004592 94.0
DTH2_k127_8852605_0 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 572.0
DTH2_k127_8852605_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 430.0
DTH2_k127_8852605_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 389.0
DTH2_k127_8856487_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 605.0
DTH2_k127_8856487_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 408.0
DTH2_k127_8856487_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003811 241.0
DTH2_k127_8856487_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000001003 237.0
DTH2_k127_8856487_4 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000004303 178.0
DTH2_k127_8856487_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000002307 143.0
DTH2_k127_8879444_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 8.579e-251 780.0
DTH2_k127_8879444_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 8.996e-228 713.0
DTH2_k127_8879444_2 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002756 275.0
DTH2_k127_8879444_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000004991 64.0
DTH2_k127_8885003_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 294.0
DTH2_k127_8885003_1 LemA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006436 280.0
DTH2_k127_8885003_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005616 256.0
DTH2_k127_8885003_3 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
DTH2_k127_8885003_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002331 218.0
DTH2_k127_8885003_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000006896 212.0
DTH2_k127_8885003_6 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003713 199.0
DTH2_k127_8885003_7 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.000000000000000000000005637 104.0
DTH2_k127_8885003_8 Glycine zipper 2TM domain - - - 0.00000009868 60.0
DTH2_k127_8893294_0 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 368.0
DTH2_k127_8893294_1 - - - - 0.0000000000000000000000317 110.0
DTH2_k127_8896170_0 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 374.0
DTH2_k127_8896170_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000813 223.0
DTH2_k127_8929761_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 467.0
DTH2_k127_8929761_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 354.0
DTH2_k127_8929761_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
DTH2_k127_8929761_3 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005396 234.0
DTH2_k127_8929761_4 Belongs to the selenophosphate synthase 1 family. Class I subfamily K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000003036 199.0
DTH2_k127_8929761_5 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000001994 137.0
DTH2_k127_8929761_6 Peptidase S24-like - - - 0.00000000000000000000000000000001789 142.0
DTH2_k127_8929761_7 - - - - 0.000000000000000562 84.0
DTH2_k127_8929761_8 - - - - 0.00000000000003287 81.0
DTH2_k127_8934909_0 Multicopper oxidase K22349 - 1.16.3.3 7.383e-282 880.0
DTH2_k127_8974050_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.0 1022.0
DTH2_k127_8974050_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 251.0
DTH2_k127_8974050_2 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000008667 190.0
DTH2_k127_8977164_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 7.884e-224 698.0
DTH2_k127_8977164_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 462.0
DTH2_k127_8977164_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 374.0
DTH2_k127_8977164_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 370.0
DTH2_k127_8977164_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000001098 282.0
DTH2_k127_8977164_5 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.000000000000000000000002424 110.0
DTH2_k127_8977164_6 23S rRNA-intervening sequence protein - - - 0.0000000000000000000008686 96.0
DTH2_k127_8977164_7 pilus assembly protein FimV K08086 - - 0.00000000000000000207 90.0
DTH2_k127_8984567_0 ABC transporter K15738 - - 1.391e-281 878.0
DTH2_k127_8984567_1 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 462.0
DTH2_k127_8984567_10 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000002663 121.0
DTH2_k127_8984567_11 Pfam Fatty acid - - - 0.0000000000000000000229 91.0
DTH2_k127_8984567_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 392.0
DTH2_k127_8984567_3 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 327.0
DTH2_k127_8984567_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 311.0
DTH2_k127_8984567_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
DTH2_k127_8984567_6 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000000000000000000000001762 232.0
DTH2_k127_8984567_7 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000004814 168.0
DTH2_k127_8984567_8 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000002582 158.0
DTH2_k127_8984567_9 - - - - 0.0000000000000000000000000000000002412 150.0
DTH2_k127_8990437_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 591.0
DTH2_k127_8990437_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 333.0
DTH2_k127_9021588_0 Diguanylate cyclase - - - 7.307e-195 631.0
DTH2_k127_9021588_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 305.0
DTH2_k127_9021588_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000004976 240.0
DTH2_k127_9025021_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.483e-261 812.0
DTH2_k127_9025021_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.55e-226 721.0
DTH2_k127_9025021_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 538.0
DTH2_k127_9025021_3 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 391.0
DTH2_k127_9025021_4 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004427 250.0
DTH2_k127_9025021_5 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000004232 211.0
DTH2_k127_9025021_6 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000001475 165.0
DTH2_k127_9025021_7 Tim44 - - - 0.00000000000000000000000000000000000000003731 154.0
DTH2_k127_9025021_8 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000442 127.0
DTH2_k127_9025021_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000002041 78.0
DTH2_k127_9045716_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 7.246e-253 791.0
DTH2_k127_9045716_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 470.0
DTH2_k127_9045716_2 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004876 276.0
DTH2_k127_9045716_3 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000004055 95.0
DTH2_k127_9045716_4 - - - - 0.0000000001112 64.0
DTH2_k127_9070538_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 473.0
DTH2_k127_9070538_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 392.0
DTH2_k127_9070538_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000008698 141.0
DTH2_k127_9070538_11 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000002795 94.0
DTH2_k127_9070538_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001028 79.0
DTH2_k127_9070538_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 333.0
DTH2_k127_9070538_3 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 308.0
DTH2_k127_9070538_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006269 255.0
DTH2_k127_9070538_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000001431 192.0
DTH2_k127_9070538_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000001494 192.0
DTH2_k127_9070538_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000002692 173.0
DTH2_k127_9070538_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000002944 171.0
DTH2_k127_9070538_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000002402 155.0
DTH2_k127_9105454_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 9.523e-271 846.0
DTH2_k127_9105454_1 Isocitrate lyase K01637 - 4.1.3.1 2.388e-249 775.0
DTH2_k127_9105454_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.553e-228 712.0
DTH2_k127_9105454_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 582.0
DTH2_k127_9105454_4 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 238.0
DTH2_k127_9105454_5 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000003086 196.0
DTH2_k127_9119461_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 449.0
DTH2_k127_9119461_1 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000636 182.0
DTH2_k127_9123225_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1029.0
DTH2_k127_9123225_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.864e-253 788.0
DTH2_k127_9123225_10 Cytochrome c K08738 - - 0.0000000000000000000000000000001125 132.0
DTH2_k127_9123225_11 Cytochrome c K08738 - - 0.00000000000000000000000000001415 123.0
DTH2_k127_9123225_2 Fumarate lyase K01744 - 4.3.1.1 8.857e-219 694.0
DTH2_k127_9123225_3 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 539.0
DTH2_k127_9123225_4 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 434.0
DTH2_k127_9123225_5 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 426.0
DTH2_k127_9123225_6 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 403.0
DTH2_k127_9123225_7 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 375.0
DTH2_k127_9123225_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
DTH2_k127_9123225_9 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.0000000000000000000000000000000000000000000000000000000000001117 218.0
DTH2_k127_9142750_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 614.0
DTH2_k127_9142750_1 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000009118 193.0
DTH2_k127_9142750_2 Multidrug ABC transporter permease K02004 - - 0.0000000000000000000000000000000000000000000000008949 177.0
DTH2_k127_9154332_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1327.0
DTH2_k127_9154332_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 299.0
DTH2_k127_9154332_2 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000005181 239.0
DTH2_k127_9157145_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007573 260.0
DTH2_k127_9157145_1 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
DTH2_k127_9157145_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000005706 124.0
DTH2_k127_9157145_3 - - - - 0.000000000000000000000001386 106.0
DTH2_k127_9157145_4 - - - - 0.000000000000000000003373 105.0
DTH2_k127_9189552_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 464.0
DTH2_k127_9189552_1 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 351.0
DTH2_k127_9189552_2 Pfam cytochrome c K17230 - - 0.00000000000000000000000000000000000005155 153.0
DTH2_k127_9189552_3 PFAM Cytochrome C K17230 - - 0.000000000000000000000001354 108.0
DTH2_k127_9189552_4 response to hydrogen peroxide K08985 - - 0.0000001592 61.0
DTH2_k127_9296132_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.21e-233 728.0
DTH2_k127_9296132_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.309e-195 614.0
DTH2_k127_9296132_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 429.0
DTH2_k127_9296132_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 303.0
DTH2_k127_9296132_4 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000006579 166.0
DTH2_k127_9296132_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000005207 140.0
DTH2_k127_9296132_6 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000002042 119.0
DTH2_k127_9309380_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1035.0
DTH2_k127_9309380_1 TonB-dependent Receptor Plug K02014 - - 3.011e-251 798.0
DTH2_k127_9309380_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 534.0
DTH2_k127_9309380_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 302.0
DTH2_k127_9309380_4 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000002289 238.0
DTH2_k127_9309380_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
DTH2_k127_9309380_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000002981 108.0
DTH2_k127_9309380_7 Mut7-C ubiquitin - - - 0.00000000000000000000001721 113.0
DTH2_k127_9309380_8 - - - - 0.0000000000000002644 89.0
DTH2_k127_931837_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 9.694e-198 627.0
DTH2_k127_931837_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 482.0
DTH2_k127_931837_2 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 411.0
DTH2_k127_9456147_0 Formyl transferase K19640 - - 5.033e-204 647.0
DTH2_k127_9456147_1 Belongs to the HypD family K04654 - - 6.03e-198 626.0
DTH2_k127_9456147_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 583.0
DTH2_k127_9456147_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000002666 198.0
DTH2_k127_9456147_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000001181 117.0
DTH2_k127_9471566_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 579.0
DTH2_k127_9471566_1 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 308.0
DTH2_k127_9471566_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000003147 209.0
DTH2_k127_9471566_3 V-type proton ATPase subunit E K02121 - - 0.00000000000000000000000000000000000000000000000000000003093 209.0
DTH2_k127_9471566_4 ATP synthase subunit C K02124 - - 0.00000000000000000000000000000000000000000004092 164.0
DTH2_k127_9471566_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000001017 151.0
DTH2_k127_9471566_6 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.000000000000000000000000007875 121.0
DTH2_k127_9471566_7 - - - - 0.0000000000000000003272 91.0
DTH2_k127_9484396_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.624e-203 640.0
DTH2_k127_9484396_1 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 357.0
DTH2_k127_9484396_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009957 263.0
DTH2_k127_9484396_3 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000002032 219.0
DTH2_k127_9484396_4 Rhodanese-like domain - - - 0.0000000000000000000000000003208 126.0
DTH2_k127_9484396_5 Bacterial SH3 domain - - - 0.000000000000000000000431 110.0
DTH2_k127_9484396_6 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000001326 89.0
DTH2_k127_9524314_0 modulator of DNA gyrase K03568 - - 6.233e-260 807.0
DTH2_k127_9524314_1 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 602.0
DTH2_k127_9524314_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 319.0
DTH2_k127_9524314_3 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000005046 128.0
DTH2_k127_9524314_4 Dodecin K09165 - - 0.000000000000000000000002427 104.0
DTH2_k127_9532958_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 5.197e-204 657.0
DTH2_k127_9532958_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 527.0
DTH2_k127_9532958_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 433.0
DTH2_k127_9532958_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 379.0
DTH2_k127_9532958_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 329.0
DTH2_k127_9532958_5 Glyoxalase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001698 236.0
DTH2_k127_9532958_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000004471 118.0
DTH2_k127_9532958_7 Rubredoxin - - - 0.000000000000000000000001339 118.0
DTH2_k127_9532958_8 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000003585 59.0
DTH2_k127_9545232_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.528e-271 850.0
DTH2_k127_9545232_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 3.022e-217 679.0
DTH2_k127_9545232_10 addiction module antidote protein - - - 0.00000000000000000000000000000000000000000001152 164.0
DTH2_k127_9545232_11 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000003788 149.0
DTH2_k127_9545232_12 Alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000003941 154.0
DTH2_k127_9545232_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000003442 134.0
DTH2_k127_9545232_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000004655 141.0
DTH2_k127_9545232_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000009457 127.0
DTH2_k127_9545232_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000001765 116.0
DTH2_k127_9545232_17 PFAM Phage Tail Collar Domain - - - 0.00000000000000001024 83.0
DTH2_k127_9545232_18 toxin-antitoxin pair type II binding - - - 0.0000000000000008445 79.0
DTH2_k127_9545232_2 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 580.0
DTH2_k127_9545232_20 - - - - 0.0003042 51.0
DTH2_k127_9545232_3 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 460.0
DTH2_k127_9545232_4 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 463.0
DTH2_k127_9545232_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 356.0
DTH2_k127_9545232_6 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
DTH2_k127_9545232_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000001608 238.0
DTH2_k127_9545232_8 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
DTH2_k127_9545232_9 PFAM ATP-binding region - - - 0.0000000000000000000000000000000000000000000000000004287 197.0
DTH2_k127_9554221_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.128e-269 837.0
DTH2_k127_9554221_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 553.0
DTH2_k127_9554221_2 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 399.0
DTH2_k127_9554221_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 354.0
DTH2_k127_9554221_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000004283 251.0
DTH2_k127_9554221_5 Cytochrome c oxidase assembly protein CtaG/Cox11 K02258 - - 0.000000000000000000000000000000000000000000000000000002425 198.0
DTH2_k127_9554221_6 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000008489 109.0
DTH2_k127_9571716_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 532.0
DTH2_k127_9571716_1 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 473.0
DTH2_k127_9571716_2 Psort location Cytoplasmic, score 8.96 K02843 - - 0.00000000000000000000000000000000000000000004352 167.0
DTH2_k127_9571716_3 Zinc-finger domain - - - 0.0000000000000000000000000002722 114.0
DTH2_k127_9596786_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 570.0
DTH2_k127_9596786_1 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 368.0
DTH2_k127_9596786_2 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
DTH2_k127_9617268_0 PFAM Peptidase M16 K07263 - - 1.044e-210 662.0
DTH2_k127_9617268_1 PFAM Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 535.0
DTH2_k127_9617268_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 448.0
DTH2_k127_9617268_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 325.0
DTH2_k127_9617268_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000004155 241.0
DTH2_k127_9617268_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000002837 207.0
DTH2_k127_9617268_6 Ferredoxin - - - 0.00000000000000000000000000000000000004365 143.0
DTH2_k127_9617268_7 Ankyrin repeats (many copies) - GO:0003008,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0007010,GO:0007015,GO:0007600,GO:0007605,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0032420,GO:0032421,GO:0032426,GO:0032501,GO:0042995,GO:0043005,GO:0043226,GO:0044085,GO:0044422,GO:0044424,GO:0044463,GO:0044464,GO:0044877,GO:0050877,GO:0050954,GO:0051015,GO:0051017,GO:0061572,GO:0071840,GO:0097435,GO:0097458,GO:0098858,GO:0098862,GO:0120025,GO:0120038 - 0.00009613 48.0
DTH2_k127_963999_0 Transmembrane secretion effector - - - 2.364e-243 771.0
DTH2_k127_963999_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 7.256e-197 622.0
DTH2_k127_963999_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 355.0
DTH2_k127_963999_3 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
DTH2_k127_963999_4 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000000000000000000000000002049 214.0
DTH2_k127_963999_5 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000001245 199.0
DTH2_k127_963999_6 - - - - 0.000123 56.0
DTH2_k127_9640009_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 391.0
DTH2_k127_9640009_1 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000008937 230.0
DTH2_k127_9640009_2 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000005585 204.0
DTH2_k127_9640009_3 signal sequence binding - - - 0.0000000000000000000000001242 118.0
DTH2_k127_9660402_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 467.0
DTH2_k127_9660402_1 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 447.0
DTH2_k127_9660402_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 324.0
DTH2_k127_9660402_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001411 274.0
DTH2_k127_9660402_4 tellurite resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000193 216.0
DTH2_k127_9660402_5 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.00000000000000000000000000000000000000000000007804 177.0
DTH2_k127_9660402_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000005965 120.0
DTH2_k127_9663809_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 500.0
DTH2_k127_9663809_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 358.0
DTH2_k127_9663809_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 350.0
DTH2_k127_9663809_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000001284 213.0
DTH2_k127_9663809_4 - - - - 0.000000000000000000000000004002 115.0
DTH2_k127_9689715_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 2.102e-239 762.0
DTH2_k127_9689715_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 585.0
DTH2_k127_9689715_10 - - - - 0.0000000001393 64.0
DTH2_k127_9689715_11 Resolvase, N terminal domain - - - 0.000000001134 65.0
DTH2_k127_9689715_12 Radical SAM - - - 0.00000005626 54.0
DTH2_k127_9689715_13 - - - - 0.0003573 49.0
DTH2_k127_9689715_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 472.0
DTH2_k127_9689715_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 470.0
DTH2_k127_9689715_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 408.0
DTH2_k127_9689715_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 330.0
DTH2_k127_9689715_6 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 320.0
DTH2_k127_9689715_7 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000009271 244.0
DTH2_k127_9689715_8 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000244 251.0
DTH2_k127_9689715_9 Protein of unknown function (DUF1318) K09978 - - 0.000000000000000000000000000000000000000000000000001049 190.0
DTH2_k127_9725868_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 4.239e-204 646.0
DTH2_k127_9725868_1 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 453.0
DTH2_k127_9725868_2 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002745 260.0
DTH2_k127_9739233_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1439.0
DTH2_k127_9739233_1 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
DTH2_k127_9739233_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 362.0
DTH2_k127_9739233_3 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 331.0
DTH2_k127_9739233_4 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000001896 158.0
DTH2_k127_9739233_5 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000211 112.0
DTH2_k127_9739233_6 Binding-protein-dependent transport system inner membrane component K10002 - - 0.0000000000000000003246 98.0
DTH2_k127_9739245_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 408.0
DTH2_k127_9739245_1 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 400.0
DTH2_k127_9739245_2 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000008357 158.0
DTH2_k127_9739245_3 DNA polymerase K07075 - - 0.00000000000000000000000000000001714 130.0
DTH2_k127_9764666_0 Von Willebrand factor A K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 598.0
DTH2_k127_9764666_1 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 529.0
DTH2_k127_9764666_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 467.0
DTH2_k127_9764666_3 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 475.0
DTH2_k127_9764666_4 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 407.0
DTH2_k127_9764666_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 353.0
DTH2_k127_9764666_6 type II secretion system protein E K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 327.0
DTH2_k127_9764666_7 FR47-like protein - - - 0.000000000000000000000000000000000000000000006053 168.0
DTH2_k127_9764666_8 Diguanylate cyclase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000003964 136.0
DTH2_k127_9784230_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.103e-274 848.0
DTH2_k127_9784230_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 602.0
DTH2_k127_9784230_2 Cytochrome c oxidase, subunit K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 387.0
DTH2_k127_9784230_3 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 337.0
DTH2_k127_9784230_4 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000002178 162.0
DTH2_k127_9784230_5 FixH K09926 - - 0.000000000000000000000008254 111.0
DTH2_k127_9784230_6 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000001559 79.0
DTH2_k127_9784230_7 Cbb3-type cytochrome oxidase K00407 - - 0.00000000001071 69.0
DTH2_k127_9787966_0 Malic enzyme K00029 - 1.1.1.40 0.0 1042.0
DTH2_k127_9787966_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.291e-238 746.0
DTH2_k127_9787966_10 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 282.0
DTH2_k127_9787966_11 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009065 270.0
DTH2_k127_9787966_12 response regulator K11712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 260.0
DTH2_k127_9787966_13 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000003159 164.0
DTH2_k127_9787966_14 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000001024 162.0
DTH2_k127_9787966_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001146 109.0
DTH2_k127_9787966_2 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 2.244e-233 727.0
DTH2_k127_9787966_3 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 548.0
DTH2_k127_9787966_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 541.0
DTH2_k127_9787966_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 462.0
DTH2_k127_9787966_6 Signal transduction histidine kinase K11711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 457.0
DTH2_k127_9787966_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 388.0
DTH2_k127_9787966_8 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
DTH2_k127_9787966_9 membrane protein, terc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 305.0
DTH2_k127_9791167_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 397.0
DTH2_k127_9791167_1 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
DTH2_k127_9791167_10 glycosyl - - - 0.0000000000007038 72.0
DTH2_k127_9791167_2 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000002179 228.0
DTH2_k127_9791167_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000001396 207.0
DTH2_k127_9791167_4 - - - - 0.00000000000000000000000000000000000000000000000000000001023 216.0
DTH2_k127_9791167_5 - - - - 0.0000000000000000000000000000000000000000004344 169.0
DTH2_k127_9791167_6 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000002291 128.0
DTH2_k127_9791167_7 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000000000001823 113.0
DTH2_k127_9791167_8 Glycosyl transferase family 2 - - - 0.00000000000000000000000007625 108.0
DTH2_k127_9791167_9 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000002257 102.0
DTH2_k127_9796523_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 549.0
DTH2_k127_9796523_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 301.0
DTH2_k127_9796523_2 GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003427 267.0
DTH2_k127_9796523_4 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000004513 166.0
DTH2_k127_9796523_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000009741 128.0
DTH2_k127_9796523_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000001741 105.0
DTH2_k127_9796523_7 protein conserved in bacteria K09914 - - 0.0000006909 61.0
DTH2_k127_9808792_0 Polysaccharide biosynthesis protein - - - 1.937e-260 815.0
DTH2_k127_9808792_1 PFAM Glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004641 269.0
DTH2_k127_9812446_0 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 469.0
DTH2_k127_9812446_1 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000002114 232.0
DTH2_k127_9878904_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 530.0
DTH2_k127_9878904_1 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002388 248.0
DTH2_k127_9878904_2 permease K07089 - - 0.0000000000000000000000000000001782 124.0
DTH2_k127_9878904_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000005656 127.0
DTH2_k127_993467_0 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 301.0
DTH2_k127_993467_1 Protein of unknown function DUF99 K09120 - - 0.000000000000000000000000000000000000000000000002759 178.0
DTH2_k127_993467_2 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000004365 143.0
DTH2_k127_993467_3 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000000000000000001148 140.0
DTH2_k127_993467_4 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000001725 102.0
DTH2_k127_9957107_0 glutaminyl-tRNA K01886 - 6.1.1.18 2.662e-276 864.0
DTH2_k127_9957107_1 Participates in both transcription termination and antitermination K02600 - - 6.817e-233 734.0
DTH2_k127_9957107_10 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000007464 112.0
DTH2_k127_9957107_11 - - - - 0.00000000000001308 78.0
DTH2_k127_9957107_2 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 9.644e-225 709.0
DTH2_k127_9957107_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
DTH2_k127_9957107_4 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
DTH2_k127_9957107_5 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
DTH2_k127_9957107_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002113 235.0
DTH2_k127_9957107_7 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
DTH2_k127_9957107_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000004171 188.0
DTH2_k127_9957107_9 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000002369 164.0
DTH2_k127_9973235_0 Heat shock 70 kDa protein K04043 - - 2.036e-321 993.0
DTH2_k127_9973235_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 541.0
DTH2_k127_9973235_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 297.0
DTH2_k127_9973235_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000004758 178.0
DTH2_k127_9973235_4 PFAM membrane protein of K08972 - - 0.0000000000000000000000000000000000000253 148.0
DTH2_k127_9973235_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000004487 95.0
DTH2_k127_9975382_0 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 434.0
DTH2_k127_9975382_1 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000000000001341 235.0
DTH2_k127_9975382_2 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000008884 59.0