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Overview

ID MAG00823
Name DTH3_bin.51
Sample SMP0024
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Nitrosomonadaceae
Genus Nitrosomonas
Species Nitrosomonas sp005779435
Assembly information
Completeness (%) 60.57
Contamination (%) 1.84
GC content (%) 51.0
N50 (bp) 3,170
Genome size (bp) 1,359,944

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1583

Gene name Description KEGG GOs EC E-value Score Sequence
DTH3_k127_1003877_0 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 503.0
DTH3_k127_1003877_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 329.0
DTH3_k127_1003877_2 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 301.0
DTH3_k127_1003877_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002215 278.0
DTH3_k127_1003877_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003526 224.0
DTH3_k127_1003877_5 Aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000000007599 198.0
DTH3_k127_1003877_6 - - - - 0.0000000000000000000000000000000000000000000000001109 179.0
DTH3_k127_1003877_7 Protein of unknown function (DUF3460) - - - 0.0000000000000000000000001241 107.0
DTH3_k127_1061641_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 8.611e-284 879.0
DTH3_k127_1083236_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0 1203.0
DTH3_k127_1083236_1 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000002074 218.0
DTH3_k127_1083236_2 Phosphorylase superfamily - - - 0.000000002194 59.0
DTH3_k127_1136503_0 Biotin lipoyl attachment K01941 - 6.3.4.6 0.0 1526.0
DTH3_k127_1136503_1 amino acid - - - 1.527e-264 819.0
DTH3_k127_1136503_10 Trm112p-like protein K09791 - - 0.0000000000000000000000000000001447 123.0
DTH3_k127_1136503_11 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000003239 54.0
DTH3_k127_1136503_2 transcriptional regulator K03655 - 3.6.4.12 4.613e-209 655.0
DTH3_k127_1136503_3 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 536.0
DTH3_k127_1136503_4 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 496.0
DTH3_k127_1136503_5 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 476.0
DTH3_k127_1136503_6 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 462.0
DTH3_k127_1136503_7 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 394.0
DTH3_k127_1136503_8 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 397.0
DTH3_k127_1136503_9 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 303.0
DTH3_k127_1163190_0 Enoyl-CoA hydratase isomerase K19640 - - 4.602e-285 887.0
DTH3_k127_1163190_1 TraB family - - - 4.016e-228 711.0
DTH3_k127_1163190_2 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 589.0
DTH3_k127_1163190_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007969 226.0
DTH3_k127_1163190_4 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000406 119.0
DTH3_k127_1163190_5 ABC transporter K06147,K18893 - - 0.00000000000000002356 83.0
DTH3_k127_1207643_0 TIGRFAM Diguanylate cyclase - - - 2.247e-229 718.0
DTH3_k127_1207643_1 malic enzyme K00029 - 1.1.1.40 1.728e-201 631.0
DTH3_k127_1207643_2 TIGRFAM Phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 444.0
DTH3_k127_1228350_0 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
DTH3_k127_1228350_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000002899 229.0
DTH3_k127_1228734_0 Signal transduction histidine kinase - - - 1.866e-275 852.0
DTH3_k127_1228734_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 1.017e-202 638.0
DTH3_k127_1228734_2 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003648 282.0
DTH3_k127_1228734_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000003937 61.0
DTH3_k127_1230999_0 PFAM Multicopper oxidase, type K04753,K08100,K14588 - 1.3.3.5 1.895e-234 732.0
DTH3_k127_1230999_1 PFAM Methionine biosynthesis MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 361.0
DTH3_k127_1243119_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 503.0
DTH3_k127_1243119_1 - K12056 - - 0.0000000000000000000000000000000000000000002919 180.0
DTH3_k127_1243119_2 cytolysis by virus of host cell K01185 - 3.2.1.17 0.000000000000000000000000000000000000007685 150.0
DTH3_k127_1243119_3 lytic transglycosylase activity K02395 - - 0.0000000000000000000000000009515 118.0
DTH3_k127_1243119_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000002581 79.0
DTH3_k127_1245253_0 Histidine kinase K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 3.566e-250 781.0
DTH3_k127_1245253_1 PFAM CheW-like protein K03408 - - 0.0000000000000000000000000000000000000000000002957 169.0
DTH3_k127_1245284_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 441.0
DTH3_k127_1245284_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 414.0
DTH3_k127_1245284_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000213 203.0
DTH3_k127_1245284_3 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000004197 122.0
DTH3_k127_1273333_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 506.0
DTH3_k127_1273333_1 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 361.0
DTH3_k127_1299881_0 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 448.0
DTH3_k127_1299881_1 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 316.0
DTH3_k127_1299881_2 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000006296 78.0
DTH3_k127_1305591_0 TIGRFAM Sodium sulphate symporter K11106,K14445 - - 1.393e-255 792.0
DTH3_k127_1305591_1 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002199 224.0
DTH3_k127_1305764_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 443.0
DTH3_k127_1305764_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 409.0
DTH3_k127_1305764_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 303.0
DTH3_k127_1305764_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 287.0
DTH3_k127_1350572_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.507e-266 822.0
DTH3_k127_1350572_1 AMP-dependent synthetase - - - 2.275e-237 743.0
DTH3_k127_1350572_2 PFAM Orn DAP Arg decarboxylase 2 K01586 - 4.1.1.20 1.795e-197 624.0
DTH3_k127_1350572_3 - - - - 0.0000000000000000000000000000000000000000000001113 171.0
DTH3_k127_1350572_4 Bacterial EndoU nuclease - - - 0.0000000000000000000000000000000000000000002541 164.0
DTH3_k127_1350572_5 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.0000000000000000000000000000000000001534 143.0
DTH3_k127_1350572_6 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.00000000000000000000000000000000006321 137.0
DTH3_k127_1350572_7 - - - - 0.000000000000000000000000000001759 121.0
DTH3_k127_1350572_8 - - - - 0.000000000000000000000000006118 112.0
DTH3_k127_1350572_9 AAA domain (dynein-related subfamily) - - - 0.000000000000000001711 85.0
DTH3_k127_137840_0 UvrD REP K03657 - 3.6.4.12 2.514e-273 848.0
DTH3_k127_137840_1 TonB-dependent Receptor Plug Domain K02014 - - 7.636e-210 657.0
DTH3_k127_1392430_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 2106.0
DTH3_k127_1392430_2 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 403.0
DTH3_k127_1392430_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 362.0
DTH3_k127_1392430_4 Peroxide stress protein YaaA K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 299.0
DTH3_k127_1392430_5 Nudix hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000006121 247.0
DTH3_k127_1392430_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000001996 213.0
DTH3_k127_1392430_7 transposase activity - - - 0.000000000000000000000006778 102.0
DTH3_k127_1392430_8 cytotoxic translational repressor of toxin-antitoxin K06218 - - 0.00000000000000001443 82.0
DTH3_k127_1401419_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 1e-323 995.0
DTH3_k127_1433266_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 1.878e-296 919.0
DTH3_k127_1433266_1 adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000004816 243.0
DTH3_k127_1433266_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000007782 224.0
DTH3_k127_1455320_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 2.969e-208 650.0
DTH3_k127_1455320_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 530.0
DTH3_k127_1455320_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 438.0
DTH3_k127_147936_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.15e-230 718.0
DTH3_k127_147936_1 Domain of unknown function (DUF4156) - - - 0.0000000000000000000000000000000000000000001742 162.0
DTH3_k127_147936_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000005147 81.0
DTH3_k127_1522232_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.937e-276 854.0
DTH3_k127_1522232_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 310.0
DTH3_k127_1522232_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 309.0
DTH3_k127_1523020_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 507.0
DTH3_k127_1523020_1 Pfam Transposase DDE domain - - - 0.00000000007741 65.0
DTH3_k127_1526054_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 4.625e-212 661.0
DTH3_k127_1526054_1 Bacterial regulatory helix-turn-helix protein, lysR family K03576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 420.0
DTH3_k127_1526054_2 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000008401 203.0
DTH3_k127_1526054_3 - - - - 0.0000000000000001076 84.0
DTH3_k127_1535609_0 Rod binding protein K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 467.0
DTH3_k127_1535609_1 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000217 280.0
DTH3_k127_1535609_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000003218 188.0
DTH3_k127_1535700_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1420.0
DTH3_k127_1551107_0 PFAM Metal-dependent hydrolase HDOD - - - 1.106e-204 647.0
DTH3_k127_1551107_1 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 338.0
DTH3_k127_1551107_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000002182 235.0
DTH3_k127_1551107_3 Sporulation related domain - - - 0.000000001085 59.0
DTH3_k127_1553196_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 8.782e-198 619.0
DTH3_k127_1553196_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 8.092e-194 607.0
DTH3_k127_1553196_2 malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 494.0
DTH3_k127_1553196_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000102 79.0
DTH3_k127_1559153_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1188.0
DTH3_k127_15915_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 3.177e-202 631.0
DTH3_k127_15915_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 359.0
DTH3_k127_15915_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 315.0
DTH3_k127_15915_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000000001395 222.0
DTH3_k127_15915_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000000001736 119.0
DTH3_k127_1622930_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1045.0
DTH3_k127_1622930_1 Bacterial protein of unknown function (DUF839) K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002441 244.0
DTH3_k127_1635904_0 PFAM Aminotransferase, class V K04487 - 2.8.1.7 1.316e-210 659.0
DTH3_k127_1635904_1 fatty acid desaturase - - - 7.36e-206 647.0
DTH3_k127_1635904_2 PFAM Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 424.0
DTH3_k127_1635904_3 Histidine triad (HIT) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001596 252.0
DTH3_k127_1635904_4 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000007112 97.0
DTH3_k127_1635904_5 - - - - 0.000000000000000005235 84.0
DTH3_k127_1654_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 563.0
DTH3_k127_1654_1 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 345.0
DTH3_k127_1654_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 332.0
DTH3_k127_1654_3 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000000000000000000000006002 181.0
DTH3_k127_1720686_0 Acetyltransferase (GNAT) domain - - - 2.26e-274 856.0
DTH3_k127_1720686_1 SMART ATPase, AAA type, core K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 575.0
DTH3_k127_1720686_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001509 188.0
DTH3_k127_1731657_0 alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 7.168e-272 840.0
DTH3_k127_1731657_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 470.0
DTH3_k127_1731657_2 Zinc-finger domain - - - 0.0000000000000000000000000000000000000242 143.0
DTH3_k127_1731657_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000001933 102.0
DTH3_k127_1739169_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1024.0
DTH3_k127_1739169_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000008938 66.0
DTH3_k127_1741602_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1076.0
DTH3_k127_178781_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1105.0
DTH3_k127_1803290_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1227.0
DTH3_k127_1803290_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.11e-264 816.0
DTH3_k127_1847830_0 Belongs to the sulfur carrier protein TusA family - - - 2.459e-199 627.0
DTH3_k127_1847830_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000007817 214.0
DTH3_k127_1847830_2 - - - - 0.000000000000000000000000000000000000000000000000000000006733 199.0
DTH3_k127_1894896_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 582.0
DTH3_k127_1894896_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000256 276.0
DTH3_k127_1894896_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001494 258.0
DTH3_k127_1894896_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000008194 214.0
DTH3_k127_1894896_4 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000002416 176.0
DTH3_k127_1894896_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000004738 89.0
DTH3_k127_1894896_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000009636 63.0
DTH3_k127_1925354_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 358.0
DTH3_k127_1925354_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 319.0
DTH3_k127_1925354_2 invasion associated locus B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001774 279.0
DTH3_k127_1925354_3 Domain of unknown function (DUF2024) - - - 0.00000000000000000000000000000000000000000000001102 171.0
DTH3_k127_1925354_4 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000004175 149.0
DTH3_k127_1994171_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 545.0
DTH3_k127_1994171_1 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 364.0
DTH3_k127_1994171_2 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 325.0
DTH3_k127_1994171_3 SURF1-like protein - - - 0.000000000000000000000000000000000002141 146.0
DTH3_k127_2103032_0 Zinc-binding dehydrogenase K12957,K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 557.0
DTH3_k127_2103032_1 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 370.0
DTH3_k127_2103032_2 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.0000000000000000000000000000004067 123.0
DTH3_k127_2169739_0 PFAM Chemotaxis methyl-accepting receptor, signalling K03406,K03776,K05874 - - 1.991e-252 788.0
DTH3_k127_2169739_1 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000000000002952 224.0
DTH3_k127_2169739_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000007846 64.0
DTH3_k127_2191801_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 614.0
DTH3_k127_2191801_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 495.0
DTH3_k127_2191801_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 355.0
DTH3_k127_2191801_3 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000000000000000000007855 161.0
DTH3_k127_2191801_4 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000002735 128.0
DTH3_k127_219694_0 MacB-like periplasmic core domain K02004 - - 1.159e-220 689.0
DTH3_k127_219694_1 MacB-like periplasmic core domain K02004 - - 2.05e-220 687.0
DTH3_k127_219694_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 578.0
DTH3_k127_219694_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 353.0
DTH3_k127_219694_4 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000007533 177.0
DTH3_k127_2199848_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 423.0
DTH3_k127_2199848_1 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000000000000009514 199.0
DTH3_k127_2199848_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000005552 143.0
DTH3_k127_2199848_3 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000005174 134.0
DTH3_k127_2199848_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000009201 109.0
DTH3_k127_2200485_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.29e-246 764.0
DTH3_k127_2200485_1 BT1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 465.0
DTH3_k127_2205304_0 Glycosyltransferase like family 2 K20444 - - 0.0 1356.0
DTH3_k127_2205304_1 Pfam:Methyltransf_26 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 583.0
DTH3_k127_2205304_2 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 555.0
DTH3_k127_2205304_3 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 336.0
DTH3_k127_2205304_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
DTH3_k127_2205304_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000008392 221.0
DTH3_k127_2205304_6 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000001454 190.0
DTH3_k127_225598_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1037.0
DTH3_k127_225598_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 336.0
DTH3_k127_225598_2 Diguanylate cyclase - - - 0.00002735 50.0
DTH3_k127_2259611_0 Histidine kinase K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004119 259.0
DTH3_k127_2259611_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007533 250.0
DTH3_k127_2259611_2 PFAM Signal transduction response regulator, receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000077 216.0
DTH3_k127_2259611_3 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000006592 203.0
DTH3_k127_2285274_0 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 382.0
DTH3_k127_2285274_1 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000004382 149.0
DTH3_k127_2285274_2 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000001136 103.0
DTH3_k127_236365_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1317.0
DTH3_k127_236365_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 598.0
DTH3_k127_236365_2 PFAM Fimbrial assembly K02663 - - 0.0000000000000000000000000000000000000000000000001134 182.0
DTH3_k127_2366351_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1152.0
DTH3_k127_2378683_0 PFAM MotA TolQ ExbB proton channel K03561 - - 2.771e-237 741.0
DTH3_k127_2378683_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 342.0
DTH3_k127_2378683_2 Protein of unknown function (DUF3450) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001408 275.0
DTH3_k127_2378683_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000000000000000006466 237.0
DTH3_k127_238284_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.19e-233 730.0
DTH3_k127_2391598_0 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 1.791e-217 677.0
DTH3_k127_2391598_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008665 248.0
DTH3_k127_2402781_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1287.0
DTH3_k127_2402781_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 539.0
DTH3_k127_2402781_2 TYPE 4 fimbrial BIOGENESIS K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 506.0
DTH3_k127_2402781_3 TIGRFAM glycine oxidase ThiO K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 486.0
DTH3_k127_2402781_4 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000074 258.0
DTH3_k127_2402781_5 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000000000000001122 187.0
DTH3_k127_2402781_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000000000000000000000000001401 176.0
DTH3_k127_2402924_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 539.0
DTH3_k127_2402924_1 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 301.0
DTH3_k127_2402924_2 Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001097 270.0
DTH3_k127_2402924_3 PFAM Blue (type 1) copper domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009527 224.0
DTH3_k127_2402924_4 - - - - 0.000000000000000000000000000000009527 130.0
DTH3_k127_2402924_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000006693 111.0
DTH3_k127_2402924_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000007959 101.0
DTH3_k127_2466104_0 Belongs to the ClpA ClpB family K03694 - - 1.085e-304 938.0
DTH3_k127_2466104_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000005207 175.0
DTH3_k127_2466104_2 PFAM Transposase, IS66 K07484 - - 0.00000000006159 62.0
DTH3_k127_2473708_0 Cytidylyltransferase-like - - - 9.995e-195 613.0
DTH3_k127_2473708_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000001806 198.0
DTH3_k127_2489260_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 507.0
DTH3_k127_2489260_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 425.0
DTH3_k127_2489260_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 392.0
DTH3_k127_255609_0 AcrB/AcrD/AcrF family K03296,K18138 - - 7.026e-291 899.0
DTH3_k127_255609_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18094 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 294.0
DTH3_k127_2624109_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.16e-209 653.0
DTH3_k127_2624109_1 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 257.0
DTH3_k127_269291_0 Strictosidine synthase K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 512.0
DTH3_k127_270952_0 Polysaccharide biosynthesis protein - - - 0.0 1017.0
DTH3_k127_270952_1 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.991e-262 808.0
DTH3_k127_270952_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 586.0
DTH3_k127_270952_3 Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 441.0
DTH3_k127_270952_4 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 387.0
DTH3_k127_270952_5 protein conserved in bacteria K03690 - - 0.000000000000000000000000000000000000000000000000000000000000001664 223.0
DTH3_k127_2725201_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 4.228e-294 910.0
DTH3_k127_2725201_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 503.0
DTH3_k127_2725201_2 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 288.0
DTH3_k127_2741802_0 SMART Diguanylate cyclase K13590 - 2.7.7.65 8.669e-214 675.0
DTH3_k127_2741802_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 373.0
DTH3_k127_2741802_2 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000002068 235.0
DTH3_k127_2741802_3 TIGRFAM Diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000307 85.0
DTH3_k127_2774801_0 PFAM Aminoacyl-tRNA synthetase, class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 484.0
DTH3_k127_2774801_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 389.0
DTH3_k127_2774801_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000001798 241.0
DTH3_k127_2774801_3 Transposase DDE domain - - - 0.0000000000107 66.0
DTH3_k127_2780004_0 PFAM Peptidase M16 K07263 - - 2.24e-243 760.0
DTH3_k127_2780004_1 PFAM Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 353.0
DTH3_k127_2780004_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 331.0
DTH3_k127_2780004_3 EF hand - - - 0.00000000000000000000000006387 112.0
DTH3_k127_2804609_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.271e-285 877.0
DTH3_k127_2804609_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 521.0
DTH3_k127_2804609_2 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 330.0
DTH3_k127_2804609_3 - - - - 0.00000006736 56.0
DTH3_k127_281016_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 539.0
DTH3_k127_281016_1 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 285.0
DTH3_k127_281016_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000005847 107.0
DTH3_k127_281298_0 Methionine synthase K00548 - 2.1.1.13 0.0 1216.0
DTH3_k127_281298_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 365.0
DTH3_k127_281298_2 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 282.0
DTH3_k127_2813289_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1265.0
DTH3_k127_2842507_0 Sodium:alanine symporter family K03310 - - 1.611e-198 622.0
DTH3_k127_2842507_1 TIGRFAM Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 407.0
DTH3_k127_2842507_2 nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 401.0
DTH3_k127_2842507_3 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000000000000000000000000000113 224.0
DTH3_k127_2842507_4 Protein of unknown function (DUF3450) - - - 0.000000002875 59.0
DTH3_k127_2902759_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1097.0
DTH3_k127_2902759_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.836e-208 649.0
DTH3_k127_2902759_2 modulator of DNA gyrase K03568 - - 7.303e-195 608.0
DTH3_k127_2902759_3 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 297.0
DTH3_k127_2902759_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000009564 56.0
DTH3_k127_2916623_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 606.0
DTH3_k127_2916623_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 316.0
DTH3_k127_294275_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 1.152e-220 692.0
DTH3_k127_294275_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 420.0
DTH3_k127_294275_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000001887 227.0
DTH3_k127_2943191_0 acyl-CoA dehydrogenase K06445 - - 0.0 1154.0
DTH3_k127_2943191_1 AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 445.0
DTH3_k127_296996_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.0 1077.0
DTH3_k127_296996_1 TIGRFAM Acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 467.0
DTH3_k127_2971872_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.028e-199 625.0
DTH3_k127_2971872_1 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 284.0
DTH3_k127_2971872_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006803 248.0
DTH3_k127_2971872_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000009087 129.0
DTH3_k127_2996385_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 380.0
DTH3_k127_2996385_1 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 299.0
DTH3_k127_2996385_2 Integrase core domain K07497 - - 0.00000000001145 68.0
DTH3_k127_2996385_3 PFAM Integrase catalytic region K07497 - - 0.000003396 49.0
DTH3_k127_2996385_4 PFAM transposase IS3 IS911 family protein K07483 - - 0.000008618 52.0
DTH3_k127_3005072_0 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 6.085e-267 827.0
DTH3_k127_3005072_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 586.0
DTH3_k127_3005072_2 Flagellar motor switch K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 430.0
DTH3_k127_3005072_3 flagellar assembly protein FliH K02411 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
DTH3_k127_3005072_4 Flagellar FliJ protein K02413 - - 0.000000000000000000000000000000000000000000000006231 175.0
DTH3_k127_3005072_5 Flagellar hook-length control K02414 - - 0.0000000001114 63.0
DTH3_k127_3024489_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 544.0
DTH3_k127_3024489_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000001403 122.0
DTH3_k127_3041614_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000001168 200.0
DTH3_k127_3041614_1 - - - - 0.000000000000000000000000000000000000000000000003161 181.0
DTH3_k127_3041614_2 sh3 domain protein K01448 - 3.5.1.28 0.0000000000000000000000000000000000000001255 155.0
DTH3_k127_3050615_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 8.769e-272 857.0
DTH3_k127_3050615_1 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 463.0
DTH3_k127_3050615_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004288 293.0
DTH3_k127_3050615_3 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000007958 198.0
DTH3_k127_3050615_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000158 203.0
DTH3_k127_3050615_5 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000007295 148.0
DTH3_k127_3058270_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 9.639e-291 899.0
DTH3_k127_3058270_1 Protein of unknown function (DUF2914) - - - 0.000000000000005006 78.0
DTH3_k127_307001_0 M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1131.0
DTH3_k127_307001_1 Dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 3.184e-243 755.0
DTH3_k127_307001_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 585.0
DTH3_k127_307001_3 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 414.0
DTH3_k127_307001_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 362.0
DTH3_k127_307001_5 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 338.0
DTH3_k127_307001_6 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 330.0
DTH3_k127_307001_7 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002336 273.0
DTH3_k127_307001_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000006149 176.0
DTH3_k127_30958_0 TIGRFAM TonB-dependent vitamin B12 receptor K16092 - - 2.645e-311 962.0
DTH3_k127_30958_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 373.0
DTH3_k127_30958_2 Nitroreductase family K02303,K04719 - 1.13.11.79,2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 352.0
DTH3_k127_30958_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 283.0
DTH3_k127_3107163_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1137.0
DTH3_k127_3107163_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 5.082e-282 866.0
DTH3_k127_3107163_10 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000002331 245.0
DTH3_k127_3107163_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001457 236.0
DTH3_k127_3107163_12 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000001434 139.0
DTH3_k127_3107163_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.803e-276 849.0
DTH3_k127_3107163_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 381.0
DTH3_k127_3107163_4 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 376.0
DTH3_k127_3107163_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 339.0
DTH3_k127_3107163_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 330.0
DTH3_k127_3107163_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 310.0
DTH3_k127_3107163_8 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 290.0
DTH3_k127_3107163_9 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005347 282.0
DTH3_k127_3120068_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.808e-248 771.0
DTH3_k127_3120068_1 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 474.0
DTH3_k127_3120068_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001272 263.0
DTH3_k127_3120068_3 Histidine kinase K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000008219 210.0
DTH3_k127_3120068_4 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000004065 111.0
DTH3_k127_312243_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 555.0
DTH3_k127_312243_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 496.0
DTH3_k127_3122467_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 502.0
DTH3_k127_3122467_1 Haem-degrading - - - 0.00000000000000000000000000000000000000000000002105 174.0
DTH3_k127_3129553_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.94e-224 699.0
DTH3_k127_3129553_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 451.0
DTH3_k127_3129553_2 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 390.0
DTH3_k127_3129553_3 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007681 274.0
DTH3_k127_3129553_4 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.00000000000000000001603 93.0
DTH3_k127_3129553_5 small periplasmic lipoprotein - - - 0.0000229 48.0
DTH3_k127_3142602_0 Histidine kinase K20974 - 2.7.13.3 5.308e-250 781.0
DTH3_k127_3197321_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 1.299e-204 644.0
DTH3_k127_3197321_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 553.0
DTH3_k127_3197321_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 313.0
DTH3_k127_3204176_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.008e-237 739.0
DTH3_k127_3204176_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 465.0
DTH3_k127_3215326_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1082.0
DTH3_k127_3218966_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 528.0
DTH3_k127_3218966_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 291.0
DTH3_k127_3229954_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 589.0
DTH3_k127_3229954_1 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 360.0
DTH3_k127_3229954_2 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000000000000000000000000000000000000007239 203.0
DTH3_k127_3233339_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1017.0
DTH3_k127_3233339_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000134 284.0
DTH3_k127_3274914_0 PFAM Copper resistance D K07245 - - 0.0 1022.0
DTH3_k127_3274914_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000002649 115.0
DTH3_k127_3275724_0 PFAM Major facilitator superfamily MFS-1 - - - 2.173e-215 674.0
DTH3_k127_3275724_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 5.997e-199 621.0
DTH3_k127_3275724_2 Helix-turn-helix XRE-family like proteins K18831 - - 0.000000000000000000000000000000000000000000000000000000000000000000005795 235.0
DTH3_k127_3275724_3 addiction module killer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001232 222.0
DTH3_k127_3275724_4 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000000000000000000000000000000000009378 196.0
DTH3_k127_3275724_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000002108 192.0
DTH3_k127_3275724_6 Bacteriophage replication gene A protein (GPA) - - - 0.00000000000008699 72.0
DTH3_k127_3275724_7 Domain of unknown function (DUF3362) - - - 0.0000008472 51.0
DTH3_k127_3281334_0 Regulator of K conductance, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 380.0
DTH3_k127_3281334_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001471 250.0
DTH3_k127_3281334_2 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003075 248.0
DTH3_k127_3281334_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001682 240.0
DTH3_k127_3281334_4 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0005817 44.0
DTH3_k127_3346891_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 592.0
DTH3_k127_3346891_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 526.0
DTH3_k127_3346891_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 395.0
DTH3_k127_3346891_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000829 256.0
DTH3_k127_3346891_4 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000000000006975 225.0
DTH3_k127_3346891_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000002731 102.0
DTH3_k127_3415913_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.912e-218 681.0
DTH3_k127_3415913_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 607.0
DTH3_k127_3415913_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 601.0
DTH3_k127_3415913_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 359.0
DTH3_k127_3415913_4 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 340.0
DTH3_k127_3415913_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 339.0
DTH3_k127_3418515_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 595.0
DTH3_k127_3418515_1 outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 309.0
DTH3_k127_3418515_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.000000000000000000000000000000000000000001183 157.0
DTH3_k127_3419364_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
DTH3_k127_3419364_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000006936 250.0
DTH3_k127_3440277_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1007.0
DTH3_k127_34448_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 484.0
DTH3_k127_34448_1 - - - - 0.000000000000000000000000000000000000000000001273 169.0
DTH3_k127_34448_2 PFAM Transposase, IS4-like K07481 - - 0.000000000000000000000000001068 113.0
DTH3_k127_3472861_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000002214 255.0
DTH3_k127_3472861_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001351 243.0
DTH3_k127_3472861_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000000002203 222.0
DTH3_k127_3472861_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000005057 199.0
DTH3_k127_3472861_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000001023 157.0
DTH3_k127_3472861_5 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000001481 137.0
DTH3_k127_3475745_0 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 313.0
DTH3_k127_3475745_1 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 295.0
DTH3_k127_3475745_2 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000001731 231.0
DTH3_k127_3475745_3 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000000000000000003272 224.0
DTH3_k127_3475745_4 Flagellar basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000003851 162.0
DTH3_k127_3537103_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.895e-222 692.0
DTH3_k127_3537103_1 - - - - 0.0000001772 54.0
DTH3_k127_3557712_0 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 592.0
DTH3_k127_3557712_1 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002935 239.0
DTH3_k127_3557712_2 Type II secretory pathway, pseudopilin - - - 0.000000000000000000000000000000000000000000000000000000000000000004645 231.0
DTH3_k127_3557712_3 PFAM type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000001165 207.0
DTH3_k127_3557712_4 to AA sequence GI 30249492 - - - 0.0000000111 55.0
DTH3_k127_3597109_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0 1338.0
DTH3_k127_3597109_1 RNA-binding K14761 - - 0.0000000000000000000000000000000000005906 140.0
DTH3_k127_3601198_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1194.0
DTH3_k127_3601198_1 pdz dhr glgf - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 522.0
DTH3_k127_3601198_2 Domain of unknown function (DUF3362) - - - 0.000004886 48.0
DTH3_k127_3639441_0 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K21721 - 1.4.1.1,1.5.1.51,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 484.0
DTH3_k127_3639441_1 protein synthesis factor, GTP-binding K06207 - - 0.00000000000000000000000000003046 117.0
DTH3_k127_3639441_2 - - - - 0.0000000000000000000722 90.0
DTH3_k127_3705914_0 Chromate transporter K07240 - - 8.226e-201 634.0
DTH3_k127_3705914_1 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000000000000000000001827 165.0
DTH3_k127_3705914_2 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000002944 73.0
DTH3_k127_3709118_0 PFAM Cytochrome c, class I - - - 1.63e-223 698.0
DTH3_k127_3709118_1 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000686 272.0
DTH3_k127_3709118_2 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000005395 229.0
DTH3_k127_3715673_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 4.522e-199 623.0
DTH3_k127_3715673_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 365.0
DTH3_k127_3715673_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000001427 202.0
DTH3_k127_3723367_0 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 518.0
DTH3_k127_3723367_1 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 430.0
DTH3_k127_3723367_2 - - - - 0.0000000000000000000000002681 105.0
DTH3_k127_3726937_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 397.0
DTH3_k127_3726937_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 331.0
DTH3_k127_3726937_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000006422 244.0
DTH3_k127_3726937_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.00000000000000000003244 94.0
DTH3_k127_376632_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1191.0
DTH3_k127_376632_1 Belongs to the CarA family K01956 - 6.3.5.5 3.054e-225 701.0
DTH3_k127_3792996_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.948e-255 788.0
DTH3_k127_3792996_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.06e-225 700.0
DTH3_k127_3792996_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 1.058e-209 654.0
DTH3_k127_3792996_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 408.0
DTH3_k127_3825238_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.9e-322 993.0
DTH3_k127_3825238_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000001058 169.0
DTH3_k127_3825238_3 Domain of unknown function (DUF3362) - - - 0.00006735 46.0
DTH3_k127_3906178_0 ABC transporter transmembrane region K12536 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 555.0
DTH3_k127_3906178_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 402.0
DTH3_k127_3906178_2 Glycosyltransferase like family K07011 - - 0.00000000000000000000000000000000000000000000000000000000000003201 215.0
DTH3_k127_3915435_0 D-isomer specific 2-hydroxyacid dehydrogenase K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 530.0
DTH3_k127_3915435_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 419.0
DTH3_k127_3915435_2 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 411.0
DTH3_k127_3915435_3 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 401.0
DTH3_k127_3915435_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001106 237.0
DTH3_k127_3915435_5 - - - - 0.00000000000000000000000000005507 125.0
DTH3_k127_3921331_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1167.0
DTH3_k127_3921331_1 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 2.089e-249 776.0
DTH3_k127_3921331_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000007255 252.0
DTH3_k127_3921331_3 - - - - 0.00000000000000000000000000000000007209 133.0
DTH3_k127_3924326_0 PFAM Lytic transglycosylase-like, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 455.0
DTH3_k127_3924326_1 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 314.0
DTH3_k127_3924326_2 Domain of unknown function (DUF3362) - - - 0.000047 50.0
DTH3_k127_3930053_0 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 353.0
DTH3_k127_3930053_1 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 310.0
DTH3_k127_3946260_0 7 transmembrane helices usually fused to an inactive transglutaminase - - - 1.66e-272 844.0
DTH3_k127_3946260_1 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 485.0
DTH3_k127_3946260_2 Signal transduction histidine kinase, phosphotransfer (Hpt) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 467.0
DTH3_k127_3946260_3 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000000000000000000002881 211.0
DTH3_k127_3946260_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0003244 48.0
DTH3_k127_4000967_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1025.0
DTH3_k127_4000967_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.556e-249 773.0
DTH3_k127_4000967_2 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 294.0
DTH3_k127_400597_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.172e-275 850.0
DTH3_k127_400597_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 597.0
DTH3_k127_400597_2 - - - - 0.000729 44.0
DTH3_k127_4028087_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 415.0
DTH3_k127_4028087_1 PFAM Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 390.0
DTH3_k127_4028087_2 diol metabolic process K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000002203 214.0
DTH3_k127_4028503_0 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 5.997e-226 702.0
DTH3_k127_4028503_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 453.0
DTH3_k127_4028503_2 Thiamine monophosphate synthase - - - 0.0000000000000000000000000000000000000000000000009144 186.0
DTH3_k127_4053021_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 579.0
DTH3_k127_4053021_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 444.0
DTH3_k127_4053021_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001074 210.0
DTH3_k127_4053021_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000004681 200.0
DTH3_k127_4107121_0 PFAM Multicopper oxidase, type - - - 0.0 1045.0
DTH3_k127_4107121_1 lipid A ABC exporter family, fused ATPase and inner membrane subunits K06147 - - 4.937e-301 931.0
DTH3_k127_4107121_2 PFAM multicopper oxidase type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 488.0
DTH3_k127_4107121_3 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
DTH3_k127_4107121_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18094 - - 0.000000000000000000000000002716 114.0
DTH3_k127_4167755_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 2.436e-242 756.0
DTH3_k127_4167755_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 1.544e-227 712.0
DTH3_k127_4167755_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 3.105e-200 629.0
DTH3_k127_4167755_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 435.0
DTH3_k127_4167755_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 366.0
DTH3_k127_4168657_0 Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal K01153 - 3.1.21.3 0.0 1171.0
DTH3_k127_4168657_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 501.0
DTH3_k127_4168657_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 458.0
DTH3_k127_4168657_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 426.0
DTH3_k127_4168657_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 422.0
DTH3_k127_4168657_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 328.0
DTH3_k127_4168657_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000153 131.0
DTH3_k127_4214436_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1670.0
DTH3_k127_4214436_1 Ribonuclease E/G family K08301 - - 8.709e-283 872.0
DTH3_k127_4214436_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 583.0
DTH3_k127_4214436_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 487.0
DTH3_k127_4214436_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 342.0
DTH3_k127_4214436_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 320.0
DTH3_k127_4214436_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 302.0
DTH3_k127_4214436_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000009219 236.0
DTH3_k127_4214436_8 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000004519 178.0
DTH3_k127_4214436_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000001198 135.0
DTH3_k127_423705_0 HELICc2 K03722 - 3.6.4.12 0.0 1071.0
DTH3_k127_423705_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 553.0
DTH3_k127_4251087_0 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer K09952 - - 0.0 1068.0
DTH3_k127_4280281_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 478.0
DTH3_k127_4280281_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 465.0
DTH3_k127_4280281_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 381.0
DTH3_k127_4280281_3 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 376.0
DTH3_k127_4280281_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 329.0
DTH3_k127_4280281_5 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 331.0
DTH3_k127_4280281_7 - - - - 0.000008012 50.0
DTH3_k127_4336019_0 Tex-like protein N-terminal domain K06959 - - 4.821e-317 976.0
DTH3_k127_4336019_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 573.0
DTH3_k127_4336019_2 Tex-like protein N-terminal domain K06959 - - 0.00000000000000000000000000000000000000003236 153.0
DTH3_k127_4344965_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 574.0
DTH3_k127_4344965_1 extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 421.0
DTH3_k127_4344978_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 2.304e-205 651.0
DTH3_k127_4344978_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 293.0
DTH3_k127_4388349_0 ABC transporter C-terminal domain K15738 - - 5e-324 999.0
DTH3_k127_4388349_1 to AA sequence GI 30249492 - - - 0.000000000000000000000344 96.0
DTH3_k127_4395692_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 4.754e-318 990.0
DTH3_k127_4396174_0 PFAM Peptidase M17, leucyl aminopeptidase K01255 - 3.4.11.1 9.697e-264 818.0
DTH3_k127_4396174_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 439.0
DTH3_k127_4426854_0 Putative peptidoglycan binding domain K21470 - - 1.229e-221 701.0
DTH3_k127_4426854_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.00000000000000001784 81.0
DTH3_k127_4481620_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1313.0
DTH3_k127_4481620_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 359.0
DTH3_k127_4481620_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 295.0
DTH3_k127_4481620_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004839 268.0
DTH3_k127_4481620_4 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000000000000000004658 233.0
DTH3_k127_4485465_0 OsmC-like protein K06889,K07397 - - 2.618e-206 648.0
DTH3_k127_4485465_1 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 489.0
DTH3_k127_4485465_2 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 376.0
DTH3_k127_4485465_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000001995 231.0
DTH3_k127_4485465_4 PFAM RNA-binding S4 K04762 - - 0.00000000000000000000000000000000000000000000000000000006612 198.0
DTH3_k127_4515007_0 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 325.0
DTH3_k127_4515007_1 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.0000000000000000000000000000000000000000000000000000004023 194.0
DTH3_k127_4515007_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000003083 134.0
DTH3_k127_4515007_3 - - - - 0.0000000000000000000000000000000963 128.0
DTH3_k127_4532882_0 cytochrome C peroxidase - - - 0.0 1079.0
DTH3_k127_4532882_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 370.0
DTH3_k127_4534670_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 571.0
DTH3_k127_4534670_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 332.0
DTH3_k127_4534670_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001574 269.0
DTH3_k127_4534670_3 TIGRFAM Methionine sulphoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005948 266.0
DTH3_k127_4534670_4 - - - - 0.000000001274 60.0
DTH3_k127_4548264_0 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 431.0
DTH3_k127_4548264_1 Glutathione S-transferase, N-terminal domain K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 392.0
DTH3_k127_4548264_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 332.0
DTH3_k127_4548264_3 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000005867 158.0
DTH3_k127_4555933_0 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 354.0
DTH3_k127_4555933_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 288.0
DTH3_k127_4555933_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005906 269.0
DTH3_k127_4555933_3 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.0000000000000000000000000000000000000000000007399 169.0
DTH3_k127_4555933_4 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000006648 127.0
DTH3_k127_4563047_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.616e-304 935.0
DTH3_k127_4563047_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 501.0
DTH3_k127_4563047_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 299.0
DTH3_k127_4563047_3 Domain of unknown function (DUF4845) - - - 0.0000000000000000000000000000000000000000101 156.0
DTH3_k127_4568151_0 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 543.0
DTH3_k127_4568151_1 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004108 258.0
DTH3_k127_4568151_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000238 228.0
DTH3_k127_4568151_3 PIN domain - - - 0.0000003356 53.0
DTH3_k127_4575650_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.609e-230 715.0
DTH3_k127_4575650_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
DTH3_k127_4575650_2 - - - - 0.000000000000000000000002914 102.0
DTH3_k127_4643296_0 PFAM Peptidase S24 S26A S26B, conserved region K03503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 342.0
DTH3_k127_4643296_1 outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003175 261.0
DTH3_k127_4643296_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000006252 184.0
DTH3_k127_4643296_3 - - - - 0.000000000000000000000000000000000000000000000000003951 183.0
DTH3_k127_4656165_0 Lysin motif K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 362.0
DTH3_k127_4656165_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000943 253.0
DTH3_k127_4656165_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000475 219.0
DTH3_k127_4673274_0 PFAM Peptidase M18 K01267 - 3.4.11.21 3.199e-243 755.0
DTH3_k127_4673274_1 PFAM Copper resistance D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 535.0
DTH3_k127_4673274_2 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001627 248.0
DTH3_k127_4730231_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.037e-279 860.0
DTH3_k127_475971_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.09e-254 788.0
DTH3_k127_475971_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 555.0
DTH3_k127_475971_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 452.0
DTH3_k127_475971_3 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 404.0
DTH3_k127_4767124_0 Lipocalin-like domain - - - 4.157e-197 625.0
DTH3_k127_4767124_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000002627 238.0
DTH3_k127_4767124_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000002432 207.0
DTH3_k127_4777534_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 1.688e-222 694.0
DTH3_k127_4777534_1 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 544.0
DTH3_k127_4777534_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 361.0
DTH3_k127_4777534_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004145 276.0
DTH3_k127_4802186_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 1.842e-203 637.0
DTH3_k127_4802186_1 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 591.0
DTH3_k127_4821510_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000003844 109.0
DTH3_k127_4821510_1 Bacterial membrane protein, YfhO - - - 0.00003766 57.0
DTH3_k127_4824452_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 329.0
DTH3_k127_4824452_1 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 291.0
DTH3_k127_4824452_2 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000218 194.0
DTH3_k127_4824452_3 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000000000000000000000003392 171.0
DTH3_k127_4824452_4 Helix-turn-helix domain K07726 - - 0.00000000000000000000000000000002902 127.0
DTH3_k127_4824825_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1187.0
DTH3_k127_4827745_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1190.0
DTH3_k127_4827745_1 Belongs to the CarB family K01955 - 6.3.5.5 4.721e-255 788.0
DTH3_k127_4827745_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 422.0
DTH3_k127_4827745_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 337.0
DTH3_k127_4827745_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 323.0
DTH3_k127_4827745_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 292.0
DTH3_k127_4827745_6 CRS1_YhbY K07574 - - 0.00000000000000000000000000000000000000000000000003095 180.0
DTH3_k127_4836520_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 428.0
DTH3_k127_4836520_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 407.0
DTH3_k127_4836520_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000001377 231.0
DTH3_k127_4846003_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 485.0
DTH3_k127_4846003_1 Glycosyltransferase like family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 284.0
DTH3_k127_4846003_2 Glycosyltransferase like family K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006388 253.0
DTH3_k127_4864946_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.503e-207 646.0
DTH3_k127_4864946_1 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004914 259.0
DTH3_k127_4864946_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000000004416 225.0
DTH3_k127_4864946_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000000005972 173.0
DTH3_k127_4864946_4 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000003879 164.0
DTH3_k127_4864946_5 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000000000000000000000000005278 139.0
DTH3_k127_4864946_6 Cytochrome c - - - 0.000000000000000000000000001536 113.0
DTH3_k127_4903156_0 Belongs to the peptidase S1C family K04691,K04772 - - 2.438e-203 638.0
DTH3_k127_4903156_1 BT1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 501.0
DTH3_k127_4903156_2 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 408.0
DTH3_k127_4920406_0 Formate acetyltransferase K00656 - 2.3.1.54 2.566e-257 807.0
DTH3_k127_4920406_1 Formate acetyltransferase K00656 - 2.3.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000294 248.0
DTH3_k127_4934495_0 4Fe-4S double cluster binding domain K11473 - - 2.624e-211 662.0
DTH3_k127_4934495_1 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 496.0
DTH3_k127_4934495_2 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 299.0
DTH3_k127_4934495_3 - - - - 0.0000000000000000000000000000000000000000000006771 169.0
DTH3_k127_4949530_0 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 448.0
DTH3_k127_4949530_1 Subtilase family K08651,K14645 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000001134 261.0
DTH3_k127_4949530_2 Protein of unknown function (DUF2868) - - - 0.0000001065 54.0
DTH3_k127_4958399_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 394.0
DTH3_k127_4958399_1 UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 336.0
DTH3_k127_4958399_2 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 295.0
DTH3_k127_4968709_0 DNA polymerase X family K02347 - - 5.119e-318 980.0
DTH3_k127_4968709_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.101e-267 829.0
DTH3_k127_4968709_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 1.632e-228 715.0
DTH3_k127_4968709_3 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 361.0
DTH3_k127_4968709_4 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000008303 253.0
DTH3_k127_4968709_5 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001526 231.0
DTH3_k127_4968709_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000008366 190.0
DTH3_k127_4968709_7 pyruvate-flavodoxin oxidoreductase activity - - - 0.00001005 49.0
DTH3_k127_49805_0 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 6.332e-209 655.0
DTH3_k127_49805_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 390.0
DTH3_k127_49805_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000000000000000001566 86.0
DTH3_k127_4990072_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 8.065e-288 885.0
DTH3_k127_4990072_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.782e-223 700.0
DTH3_k127_4990072_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 354.0
DTH3_k127_4990072_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000002654 177.0
DTH3_k127_4990072_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000007774 158.0
DTH3_k127_4990072_5 - - - - 0.000000000000000000000000000000000000008317 145.0
DTH3_k127_5013107_0 PFAM aminotransferase, class I K00652 - 2.3.1.47 6.082e-195 612.0
DTH3_k127_5013107_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003778 267.0
DTH3_k127_5013107_2 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000001941 127.0
DTH3_k127_5016990_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000011 168.0
DTH3_k127_5016990_1 Methyltransferase domain - - - 0.0007843 43.0
DTH3_k127_502367_0 Response regulator receiver modulated diguanylate cyclase - - - 1.032e-289 899.0
DTH3_k127_502367_1 PFAM TonB-dependent receptor, plug K02014,K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 605.0
DTH3_k127_502367_2 PFAM TonB-dependent receptor, plug K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 324.0
DTH3_k127_502367_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.00000000000000000000000000000000000000000000005892 173.0
DTH3_k127_502367_4 Response regulator receiver modulated diguanylate cyclase - - - 0.0000002778 52.0
DTH3_k127_5027093_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.936e-263 814.0
DTH3_k127_5027093_1 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 1.153e-218 681.0
DTH3_k127_5027093_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 472.0
DTH3_k127_5027093_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 307.0
DTH3_k127_5027093_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003468 247.0
DTH3_k127_5027093_5 PFAM Multicopper oxidase, type K04753,K08100,K14588 - 1.3.3.5 0.000000000000000000000000000000000003145 137.0
DTH3_k127_5027415_0 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 460.0
DTH3_k127_5027415_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000000001184 226.0
DTH3_k127_5027415_2 Transporter associated domain K06189 - - 0.000000000000000000000000000000000006228 136.0
DTH3_k127_502747_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 421.0
DTH3_k127_502747_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 405.0
DTH3_k127_502747_2 YGGT family K02221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 316.0
DTH3_k127_502747_3 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000000000003612 208.0
DTH3_k127_502747_4 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000009673 182.0
DTH3_k127_502747_5 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000000000002042 134.0
DTH3_k127_504114_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 585.0
DTH3_k127_504114_1 PFAM IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 360.0
DTH3_k127_5088576_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 2.246e-199 623.0
DTH3_k127_5088576_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 591.0
DTH3_k127_5088576_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 539.0
DTH3_k127_5088576_3 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 338.0
DTH3_k127_5088576_4 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 327.0
DTH3_k127_5088576_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000943 259.0
DTH3_k127_5088576_6 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000008046 189.0
DTH3_k127_5089471_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 419.0
DTH3_k127_5089471_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 409.0
DTH3_k127_5089471_2 FlgN protein K02399 - - 0.000000000000000000000000000000000000000000000000000000000000002235 220.0
DTH3_k127_5104900_0 Protein of unknown function, DUF484 K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 583.0
DTH3_k127_5104900_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 508.0
DTH3_k127_5116492_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 442.0
DTH3_k127_5116492_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 316.0
DTH3_k127_5128308_0 SMART ATPase, AAA type, core K06148 - - 1.127e-266 825.0
DTH3_k127_5128308_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000003436 113.0
DTH3_k127_5149550_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1022.0
DTH3_k127_5149550_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 392.0
DTH3_k127_5149550_2 Sensors of blue-light using FAD - - - 0.0000000000000000000000001426 123.0
DTH3_k127_5166665_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 6.862e-211 658.0
DTH3_k127_5166665_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 489.0
DTH3_k127_5166665_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 425.0
DTH3_k127_5166665_3 Tellurite resistance protein TerB K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 425.0
DTH3_k127_5166665_4 Protein of unknown function (DUF1524) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 304.0
DTH3_k127_5166665_5 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 288.0
DTH3_k127_5166665_6 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002631 267.0
DTH3_k127_5166665_7 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000000000000005022 152.0
DTH3_k127_5166665_8 transporter antisigma-factor antagonist STAS K07122 - - 0.00000000000000000000000000000000532 130.0
DTH3_k127_5166665_9 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.000004673 49.0
DTH3_k127_5169425_0 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 467.0
DTH3_k127_5169425_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 370.0
DTH3_k127_5169425_2 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 308.0
DTH3_k127_5169425_3 - - - - 0.000000000000000000000000000000006027 128.0
DTH3_k127_5170268_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.595e-301 932.0
DTH3_k127_5170268_1 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 351.0
DTH3_k127_5170268_2 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000634 155.0
DTH3_k127_520658_0 type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 566.0
DTH3_k127_520658_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 294.0
DTH3_k127_520658_2 carbon utilization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001456 282.0
DTH3_k127_520658_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001527 274.0
DTH3_k127_5210650_0 Domain of unknown function (DUF4432) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 460.0
DTH3_k127_5210650_1 mannitol metabolic process K00009 - 1.1.1.17 0.000000000000000000000000000000000000000000004011 170.0
DTH3_k127_5210650_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000002758 75.0
DTH3_k127_5248266_0 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 585.0
DTH3_k127_5248266_1 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001412 266.0
DTH3_k127_5248266_2 Lysin motif - - - 0.00000000000000000000000000000000000004158 143.0
DTH3_k127_5291907_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 552.0
DTH3_k127_5291907_1 Multicopper oxidase K00368,K08100 - 1.3.3.5,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 479.0
DTH3_k127_5291907_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 321.0
DTH3_k127_5296988_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 567.0
DTH3_k127_5296988_1 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 346.0
DTH3_k127_5340366_0 PFAM Aminoacyl-tRNA synthetase, class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 450.0
DTH3_k127_5340366_1 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 402.0
DTH3_k127_5340366_2 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 372.0
DTH3_k127_5340366_3 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 283.0
DTH3_k127_5346312_0 Type II secretion system K02455 - - 4.115e-226 705.0
DTH3_k127_5346312_1 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000004566 181.0
DTH3_k127_5346312_2 type II secretion system protein E K02454 - - 0.0000000000000001367 80.0
DTH3_k127_5347561_0 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 371.0
DTH3_k127_5347561_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 370.0
DTH3_k127_5347561_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002512 267.0
DTH3_k127_5347561_3 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000001139 189.0
DTH3_k127_537371_0 Involved in the TonB-independent uptake of proteins K03641 - - 4.38e-248 769.0
DTH3_k127_537371_1 TolA C-terminal K03646 - - 0.000000000000000002269 84.0
DTH3_k127_537371_2 Belongs to the ompA family K03640 - - 0.00000000001025 65.0
DTH3_k127_538652_0 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 436.0
DTH3_k127_538652_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 433.0
DTH3_k127_538652_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 284.0
DTH3_k127_538652_3 Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001046 283.0
DTH3_k127_538652_4 KR domain K00059 - 1.1.1.100 0.0000000000000000000000002842 107.0
DTH3_k127_5393917_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 2.359e-235 736.0
DTH3_k127_5393917_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 2.473e-200 635.0
DTH3_k127_5393917_2 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000000000000000000001568 233.0
DTH3_k127_5393917_3 Domain of unknown function (DUF3362) - - - 0.00000000001025 65.0
DTH3_k127_5410466_0 Na H antiporter NhaC K03315 - - 5.086e-234 731.0
DTH3_k127_5410466_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 597.0
DTH3_k127_5410466_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 404.0
DTH3_k127_5410466_3 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003143 278.0
DTH3_k127_5410466_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000005715 235.0
DTH3_k127_5410466_5 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000000000000000002162 124.0
DTH3_k127_5439195_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.707e-249 773.0
DTH3_k127_5439195_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002108 263.0
DTH3_k127_5475590_0 Belongs to the GSP D family K02666 - - 5.723e-249 778.0
DTH3_k127_5475590_1 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004959 254.0
DTH3_k127_5475590_2 PFAM Pilus assembly protein K02665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001299 245.0
DTH3_k127_5483936_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 3.612e-236 732.0
DTH3_k127_5483936_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 488.0
DTH3_k127_5483936_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 454.0
DTH3_k127_5500803_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.004e-246 764.0
DTH3_k127_5500803_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 507.0
DTH3_k127_5500803_2 Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000504 279.0
DTH3_k127_5500803_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000001405 142.0
DTH3_k127_5535_0 PFAM formate nitrite transporter K02598,K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 483.0
DTH3_k127_5535_1 Zinc-dependent metalloprotease K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 322.0
DTH3_k127_5535_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000005579 149.0
DTH3_k127_5560255_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 587.0
DTH3_k127_5560255_1 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 518.0
DTH3_k127_5580332_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 1.008e-278 858.0
DTH3_k127_5580332_1 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 300.0
DTH3_k127_5580332_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000001979 133.0
DTH3_k127_5580990_0 Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor K03406,K03776 - - 9.208e-242 756.0
DTH3_k127_5580990_1 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor K07675 - 2.7.13.3 7.376e-240 748.0
DTH3_k127_5580990_2 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 582.0
DTH3_k127_5580990_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000007285 211.0
DTH3_k127_5580990_4 PFAM Signal transduction response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000001181 187.0
DTH3_k127_5580990_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000000000005754 142.0
DTH3_k127_5592445_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 2.841e-274 847.0
DTH3_k127_5592445_1 cytochrome complex assembly K02200,K04018,K19225,K21007 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 371.0
DTH3_k127_5592445_3 Domain of unknown function (DUF3362) - - - 0.00006547 45.0
DTH3_k127_5595640_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.197e-293 907.0
DTH3_k127_5595640_1 - - - - 0.00000000000000000000000000000000000000000000000001512 180.0
DTH3_k127_5620657_0 type II secretion system protein E K02454 - - 1.203e-234 733.0
DTH3_k127_5620657_1 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 385.0
DTH3_k127_5620657_2 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 299.0
DTH3_k127_5620657_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001862 237.0
DTH3_k127_5621496_0 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 376.0
DTH3_k127_5621496_1 NAD(P)H-binding K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000001243 246.0
DTH3_k127_5621496_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000521 203.0
DTH3_k127_5624592_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.31e-255 793.0
DTH3_k127_5624592_1 Regulatory protein, FmdB family - - - 0.00000000000394 66.0
DTH3_k127_5645623_0 PFAM Peptidase S1 S6, chymotrypsin Hap K08070 - 1.3.1.74 3.176e-214 668.0
DTH3_k127_5645623_1 PFAM heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 339.0
DTH3_k127_5645623_2 Thioredoxin-like domain K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000007051 244.0
DTH3_k127_5645623_3 MerR HTH family regulatory protein K18997 - - 0.000000000000000000000000000000000000001024 153.0
DTH3_k127_5645623_4 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000005713 147.0
DTH3_k127_5655991_0 TonB-dependent Receptor Plug Domain K02014 - - 9.567e-210 658.0
DTH3_k127_5655991_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 429.0
DTH3_k127_5655991_2 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000001494 235.0
DTH3_k127_5655991_3 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000001324 230.0
DTH3_k127_5655991_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000001262 167.0
DTH3_k127_5655991_5 - - - - 0.0000000000000000000001147 101.0
DTH3_k127_5655991_6 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0000001234 56.0
DTH3_k127_5688616_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.099e-272 843.0
DTH3_k127_5688616_1 Molecular chaperone. Has ATPase activity K04079 - - 8.135e-208 650.0
DTH3_k127_5688616_2 Domain of unknown function (DUF3362) - - - 0.00000000003664 64.0
DTH3_k127_5717576_0 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 3.423e-297 924.0
DTH3_k127_5717576_1 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 454.0
DTH3_k127_5717576_2 flagellar protein FliS K02422 - - 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
DTH3_k127_5717576_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000001891 218.0
DTH3_k127_5717576_4 Flagellar protein FliT K02423 - - 0.000000000000000000000000000000000000000006569 156.0
DTH3_k127_5717576_5 PFAM Flagellar protein FlaG protein K06603 - - 0.00000000000000000000000000000000001002 139.0
DTH3_k127_5717576_6 FlhB HrpN YscU SpaS Family K04061 - - 0.0000000000000000000000000000000008356 133.0
DTH3_k127_5752652_0 ribonuclease II K01147 - 3.1.13.1 2e-323 998.0
DTH3_k127_5752652_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 445.0
DTH3_k127_5752652_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 306.0
DTH3_k127_5752652_3 Protein of unknown function (DUF721) - - - 0.000000000000000000000000000000000000000000001164 169.0
DTH3_k127_5757240_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.52e-248 767.0
DTH3_k127_5757240_1 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 581.0
DTH3_k127_5757240_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 480.0
DTH3_k127_5768280_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003925 274.0
DTH3_k127_5768280_1 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001294 274.0
DTH3_k127_5768280_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000001626 152.0
DTH3_k127_5777884_0 DNA polymerase III K01141 - 3.1.11.1 1.079e-220 687.0
DTH3_k127_5777884_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004256 244.0
DTH3_k127_5791038_0 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 338.0
DTH3_k127_5791038_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 332.0
DTH3_k127_5791038_2 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001943 250.0
DTH3_k127_5791038_3 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000000000000000000000002309 220.0
DTH3_k127_5791038_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000772 216.0
DTH3_k127_5791038_5 HupE UreJ protein K03192 - - 0.0000000000000000000000000000000000000000001453 162.0
DTH3_k127_5800309_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 340.0
DTH3_k127_5800309_1 SMART Diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
DTH3_k127_5800309_2 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000002147 168.0
DTH3_k127_5800309_3 Dodecin K09165 - - 0.0000000000000000000000000000004559 124.0
DTH3_k127_5802422_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 397.0
DTH3_k127_5802422_1 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 297.0
DTH3_k127_5802422_2 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005199 251.0
DTH3_k127_5802422_3 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000003989 208.0
DTH3_k127_5802422_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000003505 204.0
DTH3_k127_5802422_5 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000007607 190.0
DTH3_k127_5802422_6 ABC transporter C-terminal domain K15738 - - 0.00000000001568 64.0
DTH3_k127_5814561_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 440.0
DTH3_k127_5814561_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001802 222.0
DTH3_k127_5823569_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.819e-306 943.0
DTH3_k127_5823569_1 MucB/RseB C-terminal domain K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 462.0
DTH3_k127_5823569_2 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 452.0
DTH3_k127_5823569_3 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 372.0
DTH3_k127_5823569_4 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001073 244.0
DTH3_k127_5823569_5 nuclear chromosome segregation - - - 0.0000000000000000000000001515 109.0
DTH3_k127_5823569_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000002091 60.0
DTH3_k127_5836788_0 PFAM TonB-dependent receptor, beta-barrel - - - 0.0 1140.0
DTH3_k127_5836788_1 TPR repeat - - - 0.00000000000000000000000003293 107.0
DTH3_k127_5845916_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 382.0
DTH3_k127_5845916_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000302 287.0
DTH3_k127_5845916_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000001944 183.0
DTH3_k127_5852698_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 570.0
DTH3_k127_5852698_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 328.0
DTH3_k127_5867735_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 512.0
DTH3_k127_5867735_1 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 488.0
DTH3_k127_5867735_2 - - - - 0.000000000000000000000000000000000001633 142.0
DTH3_k127_5885691_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 4.961e-225 700.0
DTH3_k127_5885691_1 membrane K08994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 469.0
DTH3_k127_5885691_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 440.0
DTH3_k127_5885691_3 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000007629 106.0
DTH3_k127_5894885_0 Psort location CytoplasmicMembrane, score 10.00 - - - 3.263e-220 689.0
DTH3_k127_5894885_1 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 323.0
DTH3_k127_5894885_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003543 234.0
DTH3_k127_5907002_0 Patatin-like phospholipase K07001 - - 8.246e-220 685.0
DTH3_k127_5907002_1 POT family K03305 - - 7.952e-194 616.0
DTH3_k127_5907002_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 589.0
DTH3_k127_5907002_3 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 503.0
DTH3_k127_5907002_4 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000002571 110.0
DTH3_k127_5907002_5 - - - - 0.000000000000000000002179 95.0
DTH3_k127_5912730_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.874e-240 752.0
DTH3_k127_5912730_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 502.0
DTH3_k127_5934508_0 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 468.0
DTH3_k127_5934508_1 Belongs to the flagella basal body rod proteins family K02391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 419.0
DTH3_k127_5934508_2 Flagellar basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000001513 173.0
DTH3_k127_5950661_0 Type II/IV secretion system protein K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 414.0
DTH3_k127_5966654_0 flagellar motor switch protein FliM K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 565.0
DTH3_k127_5966654_1 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
DTH3_k127_5966654_2 Flagellar motor switch K02417,K03225 - - 0.000000000000000000000000000000000000000000000000000000000000000000003465 238.0
DTH3_k127_5966654_3 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000000000001065 199.0
DTH3_k127_5966654_4 flagellar biosynthesis protein K02418 - - 0.0000000000000000000000000000000001912 136.0
DTH3_k127_5973501_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.042e-296 911.0
DTH3_k127_5973501_1 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000002853 197.0
DTH3_k127_5973501_2 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000003203 198.0
DTH3_k127_5982518_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 444.0
DTH3_k127_5982518_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 425.0
DTH3_k127_5982518_2 Universal stress protein K06149 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003619 248.0
DTH3_k127_5982518_3 Signal transduction histidine kinase, phosphotransfer (Hpt) - - - 0.0000000000000000000000000000000000000000000000000000002635 199.0
DTH3_k127_5982518_4 Domain of unknown function (DUF4173) - - - 0.0000695 46.0
DTH3_k127_603135_0 PFAM Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 512.0
DTH3_k127_603135_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 291.0
DTH3_k127_603135_2 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000003046 244.0
DTH3_k127_603135_3 Cold shock protein domain K03704 - - 0.000000000000000000000000000000000002408 138.0
DTH3_k127_6040496_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 455.0
DTH3_k127_6040496_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 410.0
DTH3_k127_6040496_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000001038 77.0
DTH3_k127_6040496_3 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000008338 49.0
DTH3_k127_6043193_0 response regulator K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 336.0
DTH3_k127_6043193_1 Domain of unknown function (DUF4372) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 326.0
DTH3_k127_6043193_2 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000002887 134.0
DTH3_k127_6043193_3 Domain of unknown function (DUF4372) - - - 0.00000000000000000000000000000000355 135.0
DTH3_k127_6043193_4 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000032 115.0
DTH3_k127_6043193_5 Domain of unknown function (DUF4372) - - - 0.000001792 50.0
DTH3_k127_6051009_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1165.0
DTH3_k127_6051009_1 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 469.0
DTH3_k127_605883_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0 1034.0
DTH3_k127_605883_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 593.0
DTH3_k127_605883_2 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002669 258.0
DTH3_k127_605883_3 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000000000000000005178 218.0
DTH3_k127_605883_4 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.00000000000000000000000000000000000000000000004402 169.0
DTH3_k127_605883_5 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000007544 129.0
DTH3_k127_6093309_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.462e-250 781.0
DTH3_k127_6093309_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000000000003633 197.0
DTH3_k127_6113579_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1620.0
DTH3_k127_6113579_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006624 274.0
DTH3_k127_6114992_0 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 482.0
DTH3_k127_6114992_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 424.0
DTH3_k127_6158181_0 PFAM Permease YjgP YjgQ K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 575.0
DTH3_k127_6158181_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 445.0
DTH3_k127_6158181_2 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 419.0
DTH3_k127_6158181_3 PFAM Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 305.0
DTH3_k127_6190_0 His Kinase A (phosphoacceptor) domain - - - 1.263e-226 710.0
DTH3_k127_6190_1 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 553.0
DTH3_k127_6190_2 endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 461.0
DTH3_k127_6190_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007426 224.0
DTH3_k127_6190_4 Competence protein ComEC Rec2 K02238 - - 0.00001158 48.0
DTH3_k127_6206948_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 7.643e-224 696.0
DTH3_k127_6206948_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 444.0
DTH3_k127_6206948_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002853 261.0
DTH3_k127_6206948_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000000001584 69.0
DTH3_k127_6231108_0 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 1.516e-206 646.0
DTH3_k127_6231108_1 Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 344.0
DTH3_k127_6231108_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000001931 198.0
DTH3_k127_6231108_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.000000000000000000000000000000000000000000000000000000254 196.0
DTH3_k127_6231108_4 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000114 85.0
DTH3_k127_6265923_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 1.522e-197 617.0
DTH3_k127_6265923_1 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 477.0
DTH3_k127_6282579_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1239.0
DTH3_k127_6282579_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 3.955e-241 750.0
DTH3_k127_6282579_2 TIGRFAM type I secretion outer membrane protein, TolC K12340 - - 2.153e-207 653.0
DTH3_k127_6282579_3 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 4.565e-198 619.0
DTH3_k127_6282579_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 516.0
DTH3_k127_6282579_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 481.0
DTH3_k127_6282579_6 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 385.0
DTH3_k127_6282579_7 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001354 261.0
DTH3_k127_6282579_9 - - - - 0.00001041 48.0
DTH3_k127_6340654_0 PFAM Di-haem cytochrome c peroxidase - - - 0.0 1248.0
DTH3_k127_63449_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 571.0
DTH3_k127_63449_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 532.0
DTH3_k127_63449_2 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000001499 192.0
DTH3_k127_63449_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000018 135.0
DTH3_k127_6346194_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 482.0
DTH3_k127_6346194_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 447.0
DTH3_k127_63635_0 Nickel-dependent hydrogenase K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 2.345e-294 908.0
DTH3_k127_63635_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 332.0
DTH3_k127_63635_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000001039 227.0
DTH3_k127_63635_3 - - - - 0.000001995 50.0
DTH3_k127_6390105_0 SMART ATPase, AAA type, core K06158 - - 1.84e-319 985.0
DTH3_k127_6390105_1 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000000000000000000362 162.0
DTH3_k127_6390105_2 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 0.00000000000000000000000000000000003962 134.0
DTH3_k127_6390105_3 PFAM Heavy metal transport detoxification protein K07213 - - 0.000000000000000001378 89.0
DTH3_k127_6394528_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002795 263.0
DTH3_k127_6394528_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003231 224.0
DTH3_k127_6394528_2 PFAM Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000000000000000000000000000000000000000003834 220.0
DTH3_k127_6394528_3 - - - - 0.000000000000000000000000000000000000000000000000000000001129 202.0
DTH3_k127_6406557_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 544.0
DTH3_k127_6406557_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 432.0
DTH3_k127_6406557_2 PFAM Polyketide cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 285.0
DTH3_k127_6406557_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001435 270.0
DTH3_k127_6406557_4 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000004782 209.0
DTH3_k127_6406557_5 Domain of unknown function (DUF3362) - - - 0.000447 42.0
DTH3_k127_6420058_0 PFAM Peptidase S11, D-alanyl-D-alanine carboxypeptidase A K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 529.0
DTH3_k127_6420058_1 PFAM Sulfotransferase K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 399.0
DTH3_k127_6420058_2 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 288.0
DTH3_k127_6440831_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 1.915e-211 663.0
DTH3_k127_6440831_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 572.0
DTH3_k127_6440831_2 Peptidase inhibitor I9 - - - 0.0000000000000000000000000001298 122.0
DTH3_k127_6443649_0 PFAM Endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 474.0
DTH3_k127_6443649_1 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 313.0
DTH3_k127_6443649_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 295.0
DTH3_k127_6443649_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008014 276.0
DTH3_k127_6443649_4 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000001107 164.0
DTH3_k127_6443649_5 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.00000000000000000000000000233 111.0
DTH3_k127_6449201_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1138.0
DTH3_k127_6449201_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 5.698e-198 621.0
DTH3_k127_6449201_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 312.0
DTH3_k127_6449201_3 shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002151 276.0
DTH3_k127_6449201_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000007719 162.0
DTH3_k127_647598_0 cysteine protease - - - 5.806e-200 623.0
DTH3_k127_647598_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001164 235.0
DTH3_k127_6494016_0 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 537.0
DTH3_k127_6494016_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 287.0
DTH3_k127_6494016_2 Dicarboxylate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001052 269.0
DTH3_k127_6494016_3 Alanine-zipper, major outer membrane lipoprotein K06078 - - 0.0000000000000000000000000000000006824 132.0
DTH3_k127_6494016_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000000001068 124.0
DTH3_k127_6514116_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 540.0
DTH3_k127_6514116_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 415.0
DTH3_k127_6514116_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 332.0
DTH3_k127_6514116_3 - - - - 0.0000000000000001414 79.0
DTH3_k127_6526299_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 460.0
DTH3_k127_6526299_1 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 447.0
DTH3_k127_6526299_2 - - - - 0.0000000000000000000000000000000000003902 145.0
DTH3_k127_6526299_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000566 114.0
DTH3_k127_6538678_0 TrkA-N domain protein K03499 - - 3.959e-270 835.0
DTH3_k127_6538678_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.833e-195 612.0
DTH3_k127_6538678_2 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000002297 238.0
DTH3_k127_6551681_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 1.413e-237 747.0
DTH3_k127_6551681_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 566.0
DTH3_k127_6551681_2 Domain of unknown function (DUF3362) - - - 0.0000000001763 67.0
DTH3_k127_6589898_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 440.0
DTH3_k127_6589898_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 424.0
DTH3_k127_6589898_2 Nucleoside-binding outer membrane - - - 0.00000000000000000000000000000000000000000002998 164.0
DTH3_k127_6589898_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000000003506 162.0
DTH3_k127_6589898_4 HupE UreJ protein K03192 - - 0.000000000002993 67.0
DTH3_k127_6589898_5 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.000002738 50.0
DTH3_k127_6600262_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 575.0
DTH3_k127_6600262_1 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 391.0
DTH3_k127_6616559_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 488.0
DTH3_k127_6616559_1 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 465.0
DTH3_k127_6616559_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 380.0
DTH3_k127_6616559_3 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 349.0
DTH3_k127_6616559_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 344.0
DTH3_k127_6616559_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000275 242.0
DTH3_k127_664192_0 FtsX-like permease family K02004 - - 0.0 1042.0
DTH3_k127_6643220_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.967e-249 771.0
DTH3_k127_6643220_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 571.0
DTH3_k127_6643220_2 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 421.0
DTH3_k127_6643220_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 291.0
DTH3_k127_6643220_4 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008898 276.0
DTH3_k127_6643220_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 239.0
DTH3_k127_6645268_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1307.0
DTH3_k127_6675134_0 PFAM Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 417.0
DTH3_k127_6675134_1 PFAM Heat shock protein DnaJ, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000007052 222.0
DTH3_k127_6675134_2 PFAM Transposase, IS66 K07484 - - 0.00005644 45.0
DTH3_k127_6681274_0 Signal transduction histidine kinase K15011 - 2.7.13.3 1.164e-230 720.0
DTH3_k127_6681274_1 Response regulator receiver K15012 - - 0.000000000000000000000000000000000002673 138.0
DTH3_k127_6681274_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00001242 49.0
DTH3_k127_6721599_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 514.0
DTH3_k127_6721599_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000007255 170.0
DTH3_k127_6721599_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000003901 140.0
DTH3_k127_6721599_3 - - - - 0.0003345 45.0
DTH3_k127_6727038_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 605.0
DTH3_k127_6727038_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 336.0
DTH3_k127_6737515_0 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 5.647e-221 691.0
DTH3_k127_6737515_1 Sodium:dicarboxylate symporter family K11102 - - 4.184e-208 652.0
DTH3_k127_6737515_2 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 425.0
DTH3_k127_6737515_3 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
DTH3_k127_6737515_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 313.0
DTH3_k127_6737515_5 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000002164 232.0
DTH3_k127_6737515_6 Domain of unknown function (DUF3362) - - - 0.00000000001081 65.0
DTH3_k127_6740756_0 PFAM aminotransferase, class I K00842,K14155 - 4.4.1.8 1.898e-206 652.0
DTH3_k127_6740756_1 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001254 215.0
DTH3_k127_6740756_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000002868 164.0
DTH3_k127_6762234_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 582.0
DTH3_k127_6762234_1 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 362.0
DTH3_k127_6779693_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 550.0
DTH3_k127_6779693_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 508.0
DTH3_k127_6779693_2 - - - - 0.000000000000007078 77.0
DTH3_k127_6835668_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 416.0
DTH3_k127_6835668_1 tRNA (guanine-N7-)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 336.0
DTH3_k127_6851747_0 PFAM Zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 437.0
DTH3_k127_6851747_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001631 276.0
DTH3_k127_6851747_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001111 273.0
DTH3_k127_6851747_3 Response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000001199 234.0
DTH3_k127_6851747_4 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000000000000000001024 175.0
DTH3_k127_6851747_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000001763 109.0
DTH3_k127_6856801_0 Protein of unknown function (DUF3422) - - - 1.395e-235 734.0
DTH3_k127_6856801_1 L-serine dehydratase single chain form K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 378.0
DTH3_k127_6895137_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 495.0
DTH3_k127_6895137_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 479.0
DTH3_k127_6895137_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001899 278.0
DTH3_k127_6895137_3 Sodium:alanine symporter family K03310 - - 0.00000000001265 64.0
DTH3_k127_6896267_0 RNase_H superfamily - - - 4.847e-243 757.0
DTH3_k127_6896267_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 359.0
DTH3_k127_6896267_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000002385 167.0
DTH3_k127_6932984_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2299.0
DTH3_k127_6932984_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001063 260.0
DTH3_k127_6947811_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 1.86e-210 657.0
DTH3_k127_6947811_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000001352 243.0
DTH3_k127_6948726_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 9.877e-280 865.0
DTH3_k127_6948726_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 595.0
DTH3_k127_6948726_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 397.0
DTH3_k127_6948726_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
DTH3_k127_6948726_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000000000000000000009139 139.0
DTH3_k127_695641_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 8.595e-237 738.0
DTH3_k127_695641_1 tRNA rRNA methyltransferase, SpoU K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 260.0
DTH3_k127_6984050_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 606.0
DTH3_k127_6984050_1 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 376.0
DTH3_k127_6984050_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 289.0
DTH3_k127_6984050_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000365 273.0
DTH3_k127_6984050_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002533 225.0
DTH3_k127_6984050_5 transcriptional regulatory protein - - - 0.00000000000000000000000002258 108.0
DTH3_k127_6984077_0 Belongs to the peptidase S16 family - - - 4.948e-310 957.0
DTH3_k127_6984077_1 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000000004405 220.0
DTH3_k127_6984077_2 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000000046 134.0
DTH3_k127_6984077_3 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000003907 106.0
DTH3_k127_6984077_4 Cation efflux family - - - 0.00000000002416 67.0
DTH3_k127_6991754_0 type II restriction enzyme, methylase - - - 0.0 1052.0
DTH3_k127_6991754_1 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 604.0
DTH3_k127_6991754_2 type II restriction enzyme, methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 464.0
DTH3_k127_6991754_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000001147 75.0
DTH3_k127_6991754_4 Belongs to the peptidase S16 family - - - 0.0000006155 51.0
DTH3_k127_699603_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 3.272e-307 952.0
DTH3_k127_7014979_0 PFAM MgtC SapB transporter - - - 6.621e-219 684.0
DTH3_k127_7014979_1 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 361.0
DTH3_k127_7014979_2 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000006633 190.0
DTH3_k127_7030604_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 9.778e-222 694.0
DTH3_k127_7030604_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 492.0
DTH3_k127_7030604_2 Polysaccharide biosynthesis protein K02473,K08679 - 5.1.3.6,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 421.0
DTH3_k127_7030604_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 415.0
DTH3_k127_7030604_4 PFAM Uncharacterised conserved protein UCP030820 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 301.0
DTH3_k127_7081328_0 Uncharacterized protein family (UPF0051) K09014 - - 7.284e-306 938.0
DTH3_k127_7081328_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 3.679e-245 766.0
DTH3_k127_7081328_10 Domain of unknown function (DUF3362) - - - 0.000000006356 57.0
DTH3_k127_7081328_2 Uncharacterized protein family (UPF0051) K09015 - - 1.449e-215 676.0
DTH3_k127_7081328_3 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 471.0
DTH3_k127_7081328_4 Scaffold protein Nfu/NifU N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 354.0
DTH3_k127_7081328_5 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 297.0
DTH3_k127_7081328_6 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005197 274.0
DTH3_k127_7081328_7 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000001814 211.0
DTH3_k127_7081328_8 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000000009069 199.0
DTH3_k127_7081328_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02657 - - 0.00000000000000000000000009622 114.0
DTH3_k127_7097045_0 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 3.01e-259 805.0
DTH3_k127_7097045_1 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000003474 219.0
DTH3_k127_7097045_2 - - - - 0.0000000000000000000000000000000000000131 147.0
DTH3_k127_7097045_3 Helix-hairpin-helix domain - - - 0.00000000000000004168 86.0
DTH3_k127_7097045_4 Domain of unknown function (DUF3362) - - - 0.000000001861 58.0
DTH3_k127_709884_0 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 2.736e-239 751.0
DTH3_k127_709884_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 309.0
DTH3_k127_709884_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000002176 218.0
DTH3_k127_709884_3 PFAM Peptidyl-prolyl cis-trans isomerase, cyclophilin-type K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002023 182.0
DTH3_k127_7115951_0 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 439.0
DTH3_k127_7115951_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001801 277.0
DTH3_k127_7115951_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 269.0
DTH3_k127_7115951_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000005875 256.0
DTH3_k127_7115951_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000001152 244.0
DTH3_k127_7132742_0 DNA helicase K03654 - 3.6.4.12 0.0 1039.0
DTH3_k127_7132742_1 Region found in RelA / SpoT proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001367 248.0
DTH3_k127_7176041_0 ABC transporter transmembrane region K06147 - - 1.162e-236 736.0
DTH3_k127_7176041_1 Thioredoxin K07396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 315.0
DTH3_k127_7176041_2 cellulase activity K20276 - - 0.000000000000000000000000008147 125.0
DTH3_k127_7176041_3 Helix-turn-helix domain - - - 0.000003196 50.0
DTH3_k127_7188567_0 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) - - - 0.0 1042.0
DTH3_k127_7188567_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 287.0
DTH3_k127_7188567_2 NAD dependent epimerase dehydratase family - - - 0.0002964 44.0
DTH3_k127_723694_0 SMART Peptidoglycan-binding Lysin subgroup K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 443.0
DTH3_k127_723694_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000228 253.0
DTH3_k127_723694_2 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000002803 140.0
DTH3_k127_7243766_0 TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 425.0
DTH3_k127_7243766_1 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 324.0
DTH3_k127_7243766_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001962 276.0
DTH3_k127_7243766_3 - - - - 0.0000004498 53.0
DTH3_k127_725077_0 MMPL family K07003 - - 0.0 1252.0
DTH3_k127_725077_1 glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 295.0
DTH3_k127_725077_2 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004236 281.0
DTH3_k127_726100_0 COG2873 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 5.139e-201 631.0
DTH3_k127_726100_1 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 535.0
DTH3_k127_726100_2 - - - - 0.0002798 43.0
DTH3_k127_7284657_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.889e-256 793.0
DTH3_k127_7284657_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 547.0
DTH3_k127_7284657_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001178 256.0
DTH3_k127_7284657_3 Domain of unknown function (DUF3362) - - - 0.00007283 48.0
DTH3_k127_729646_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 567.0
DTH3_k127_729646_1 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 492.0
DTH3_k127_729646_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 357.0
DTH3_k127_729646_3 E-Z type HEAT repeats - - - 0.00000000000000000000000000000000000000000001598 175.0
DTH3_k127_729646_4 - - - - 0.00006021 50.0
DTH3_k127_7332583_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1311.0
DTH3_k127_7332583_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 399.0
DTH3_k127_7332583_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 390.0
DTH3_k127_7336643_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.814e-242 756.0
DTH3_k127_7336643_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000007063 115.0
DTH3_k127_7346465_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 553.0
DTH3_k127_7346465_1 Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor K03406,K03776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 507.0
DTH3_k127_7346465_2 Protein of unknown function (DUF3135) - - - 0.000000000000000000000000000000000000000000001527 168.0
DTH3_k127_7398120_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1549.0
DTH3_k127_7478481_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 7e-323 993.0
DTH3_k127_7478481_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 477.0
DTH3_k127_7478481_2 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003656 263.0
DTH3_k127_7478481_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000005778 223.0
DTH3_k127_7478481_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000000000000000109 138.0
DTH3_k127_7483791_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.328e-320 981.0
DTH3_k127_7483791_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 471.0
DTH3_k127_7483791_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 352.0
DTH3_k127_7483791_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000266 246.0
DTH3_k127_7490492_0 Pfam Aminotransferase class I and II K02225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 424.0
DTH3_k127_7490492_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 409.0
DTH3_k127_7490492_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 399.0
DTH3_k127_7520671_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.479e-251 781.0
DTH3_k127_7520671_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 331.0
DTH3_k127_7520671_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000001363 124.0
DTH3_k127_756232_0 Ankyrin repeat K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 563.0
DTH3_k127_756232_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 370.0
DTH3_k127_756232_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.00000004199 57.0
DTH3_k127_7569405_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.965e-271 841.0
DTH3_k127_7569405_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 496.0
DTH3_k127_7569405_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001908 281.0
DTH3_k127_7569405_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000009223 97.0
DTH3_k127_760771_0 type II secretion system protein E K02670 - - 2.769e-224 698.0
DTH3_k127_760771_1 PFAM Type II secretion system protein E K02669,K12203 - - 8.341e-211 659.0
DTH3_k127_760771_10 Protein of unknown function DUF86 - - - 0.000000000006362 68.0
DTH3_k127_760771_11 Nucleotidyltransferase domain K07075 - - 0.0001674 47.0
DTH3_k127_760771_2 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 437.0
DTH3_k127_760771_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
DTH3_k127_760771_4 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004677 243.0
DTH3_k127_760771_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000003382 161.0
DTH3_k127_760771_6 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000000000003276 141.0
DTH3_k127_760771_7 Restriction endonuclease - - - 0.000000000000000000000000000001773 126.0
DTH3_k127_760771_8 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000001979 114.0
DTH3_k127_760771_9 Protein of unknown function DUF86 - - - 0.00000000000000000000000002169 111.0
DTH3_k127_7612415_0 TIGRFAM Acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 3.479e-303 934.0
DTH3_k127_7612415_1 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 1.676e-198 619.0
DTH3_k127_7612415_2 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000001192 196.0
DTH3_k127_7620664_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 9.977e-234 728.0
DTH3_k127_7620664_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 526.0
DTH3_k127_7632077_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 566.0
DTH3_k127_7632077_1 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000007693 171.0
DTH3_k127_7632077_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000002572 166.0
DTH3_k127_7648360_0 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 408.0
DTH3_k127_7648360_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 381.0
DTH3_k127_7648360_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 376.0
DTH3_k127_7648360_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 300.0
DTH3_k127_7660329_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.011e-278 861.0
DTH3_k127_7660329_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 445.0
DTH3_k127_7660329_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 432.0
DTH3_k127_7660329_3 Signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000003989 75.0
DTH3_k127_7678794_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.869e-261 807.0
DTH3_k127_7678794_1 Acts as a magnesium transporter K06213 - - 2.038e-256 796.0
DTH3_k127_7678794_2 - - - - 0.000000000000000000000000000000000000004668 149.0
DTH3_k127_7754601_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1662.0
DTH3_k127_7754601_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 561.0
DTH3_k127_7754601_2 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 388.0
DTH3_k127_7754601_3 PFAM Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000459 225.0
DTH3_k127_7754601_4 HemY protein N-terminus K02498 - - 0.00000007674 53.0
DTH3_k127_7776854_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 3.235e-267 827.0
DTH3_k127_7776854_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 506.0
DTH3_k127_7776854_2 - - - - 0.00000000000000000000000000000000000000000000000000000009562 196.0
DTH3_k127_778343_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 457.0
DTH3_k127_778343_1 Cupin domain K11312 - - 0.0000000000000000000000000000000000001973 143.0
DTH3_k127_778343_2 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000003638 131.0
DTH3_k127_7790668_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 5.202e-320 988.0
DTH3_k127_7790668_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 5.946e-255 793.0
DTH3_k127_7803187_0 Protein of unknown function (DUF3570) - - - 1.357e-242 754.0
DTH3_k127_7803187_1 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 521.0
DTH3_k127_7803187_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 517.0
DTH3_k127_7812385_0 Ammonium transporter K03320,K06580 - - 2.486e-244 760.0
DTH3_k127_7812385_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 520.0
DTH3_k127_7812385_2 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 316.0
DTH3_k127_7812385_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000024 260.0
DTH3_k127_7812385_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001631 253.0
DTH3_k127_7813812_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 604.0
DTH3_k127_7813812_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005614 259.0
DTH3_k127_7848419_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 490.0
DTH3_k127_7848419_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002535 273.0
DTH3_k127_7851075_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 2.031e-224 715.0
DTH3_k127_7853690_0 PFAM aminotransferase, class I K14260 - 2.6.1.2,2.6.1.66 4.178e-255 789.0
DTH3_k127_7853690_1 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 2.249e-230 717.0
DTH3_k127_7853690_2 - - - - 0.0000000000000000000000000000000000000000000000592 171.0
DTH3_k127_7853690_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000001675 115.0
DTH3_k127_7854231_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 4.567e-252 779.0
DTH3_k127_7854231_1 Nad-dependent epimerase dehydratase - - - 9.866e-201 626.0
DTH3_k127_788610_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 3.777e-264 819.0
DTH3_k127_788610_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000001022 186.0
DTH3_k127_7912793_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.856e-205 642.0
DTH3_k127_7912793_1 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 288.0
DTH3_k127_7912793_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002186 267.0
DTH3_k127_7912793_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
DTH3_k127_7912793_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000004817 99.0
DTH3_k127_7912793_5 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00008509 44.0
DTH3_k127_7940380_0 Histidine kinase - - - 5.649e-228 719.0
DTH3_k127_7940380_1 PFAM Signal transduction response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 371.0
DTH3_k127_7940380_2 - - - - 0.0000000000000000000000000000000000000000004707 162.0
DTH3_k127_7979990_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 1.511e-224 698.0
DTH3_k127_7979990_1 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 1.809e-195 616.0
DTH3_k127_7979990_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 472.0
DTH3_k127_7979990_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 398.0
DTH3_k127_8008043_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1002.0
DTH3_k127_8008043_1 Belongs to the thiolase family K00632 - 2.3.1.16 3.237e-235 731.0
DTH3_k127_8008043_2 PFAM Chemotaxis methyl-accepting receptor, signalling K03406,K03776,K05874 - - 0.00000000000000000000000000005777 118.0
DTH3_k127_8012250_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 576.0
DTH3_k127_8012250_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 373.0
DTH3_k127_8027656_0 Belongs to the glutamate synthase family - - - 2.203e-297 914.0
DTH3_k127_8027656_1 PFAM Bacterial extracellular solute-binding, family 1 K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 330.0
DTH3_k127_8029337_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 3.803e-201 629.0
DTH3_k127_8029337_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000005645 266.0
DTH3_k127_8049957_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008261 282.0
DTH3_k127_8049957_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000003563 214.0
DTH3_k127_8049957_2 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014,K16089 - - 0.0000000000000000000000000000000000000000000000007263 187.0
DTH3_k127_8049957_3 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000000001333 135.0
DTH3_k127_8049957_4 TonB dependent receptor K02014 - - 0.000008332 52.0
DTH3_k127_8063429_0 TIGRFAM Sodium sulphate symporter K11106,K14445 - - 1.983e-270 835.0
DTH3_k127_8114611_0 ABC transporter K06147,K18893 - - 9.446e-276 852.0
DTH3_k127_8118232_0 Response regulator receiver K02487,K03407,K06596 - 2.7.13.3 3.776e-269 836.0
DTH3_k127_8118232_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 2.641e-239 742.0
DTH3_k127_8118232_2 Bacterial regulatory helix-turn-helix protein, lysR family K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 555.0
DTH3_k127_8118232_3 - - - - 0.000000000000000000000000000000000000001574 147.0
DTH3_k127_8183785_0 Participates in both transcription termination and antitermination K02600 - - 2.777e-257 797.0
DTH3_k127_8183785_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.949e-232 729.0
DTH3_k127_8195583_0 cell shape determining protein, MreB Mrl K03569 - - 3.415e-216 672.0
DTH3_k127_8195583_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.699e-203 635.0
DTH3_k127_8195583_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 292.0
DTH3_k127_8195583_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000001005 154.0
DTH3_k127_8200796_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 514.0
DTH3_k127_8200796_1 Soluble lytic murein transglycosylase L domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 392.0
DTH3_k127_8200848_0 TIGRFAM type I secretion outer membrane protein, TolC K12538 - - 3.57e-220 689.0
DTH3_k127_8200848_1 TIGRFAM Type I secretion membrane fusion protein, HlyD K02022,K12537,K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 398.0
DTH3_k127_8230519_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 3.138e-220 692.0
DTH3_k127_8230519_1 Cytochrome c1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 432.0
DTH3_k127_8230519_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003642 238.0
DTH3_k127_82396_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 573.0
DTH3_k127_82396_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
DTH3_k127_8241150_0 PFAM aminotransferase, class I K14267 - 2.6.1.17 2.58e-211 660.0
DTH3_k127_8241150_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 529.0
DTH3_k127_8241150_2 Domain of unknown function (DUF4389) - - - 0.000000000000000001682 86.0
DTH3_k127_8244089_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 488.0
DTH3_k127_8244089_1 Periplasmic sensor hybrid histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 346.0
DTH3_k127_8244089_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000001845 90.0
DTH3_k127_8244089_3 to AA sequence GI 30249492 - - - 0.0000000111 55.0
DTH3_k127_8249783_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 5.233e-317 980.0
DTH3_k127_8249783_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 395.0
DTH3_k127_8249783_2 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 327.0
DTH3_k127_8249783_3 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009295 265.0
DTH3_k127_8259693_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 6.332e-200 627.0
DTH3_k127_8259693_1 TIGRFAM Pilus biogenesis stability type IV, PilW K02656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 382.0
DTH3_k127_8259693_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000001795 188.0
DTH3_k127_8266137_0 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 512.0
DTH3_k127_8266137_1 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 301.0
DTH3_k127_8266137_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000001378 170.0
DTH3_k127_8266137_3 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000609 131.0
DTH3_k127_8266137_4 - - - - 0.000000000000001895 78.0
DTH3_k127_8274875_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 281.0
DTH3_k127_8274875_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000003175 214.0
DTH3_k127_8274875_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00001801 51.0
DTH3_k127_8280749_0 - - - - 0.00000000000000000000000000000000000000000000000006677 183.0
DTH3_k127_8280749_1 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000001386 135.0
DTH3_k127_8280749_2 PFAM DNA polymerase, beta domain protein region - - - 0.00000000000000000000000008798 109.0
DTH3_k127_8280749_3 Transposase IS200 like K07491 - - 0.0000000000005482 72.0
DTH3_k127_8280749_4 Transposase IS200 like - - - 0.0001385 46.0
DTH3_k127_8285401_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.644e-271 838.0
DTH3_k127_8285401_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 585.0
DTH3_k127_8285401_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000002825 129.0
DTH3_k127_8303467_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1000.0
DTH3_k127_8308525_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 540.0
DTH3_k127_8308525_1 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 387.0
DTH3_k127_8308525_2 transport-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 303.0
DTH3_k127_8308525_3 Two component signalling adaptor domain K02659 - - 0.00000000000000000000000000000000000000000000000000000000007433 207.0
DTH3_k127_8308525_4 PFAM restriction modification system DNA specificity K01154 - 3.1.21.3 0.000000000000000000004544 95.0
DTH3_k127_832375_0 PFAM Major facilitator superfamily K08218 - - 1.837e-255 792.0
DTH3_k127_832375_1 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000994 233.0
DTH3_k127_832375_2 AFG1-like ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000118 185.0
DTH3_k127_8324902_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 2.278e-197 623.0
DTH3_k127_8324902_1 outer membrane efflux protein K15725 - - 0.00000000000000000000000001124 109.0
DTH3_k127_8355610_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 557.0
DTH3_k127_8355610_1 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002524 265.0
DTH3_k127_8355610_2 - - - - 0.000000000000000000000000000000000000000000000000000006336 194.0
DTH3_k127_8355610_3 - - - - 0.000000000000000000000000000000000000000000000000001028 187.0
DTH3_k127_8355610_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000001667 58.0
DTH3_k127_8363924_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1162.0
DTH3_k127_8363924_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 516.0
DTH3_k127_8363924_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 512.0
DTH3_k127_8363924_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000003795 54.0
DTH3_k127_8363924_4 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000001783 52.0
DTH3_k127_8381846_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1165.0
DTH3_k127_8381846_1 PFAM aminotransferase, class I K00812 - 2.6.1.1 1.74e-233 725.0
DTH3_k127_8381846_2 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 320.0
DTH3_k127_8381846_3 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000000000000000000000002518 170.0
DTH3_k127_8408350_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 396.0
DTH3_k127_8408350_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 390.0
DTH3_k127_8408350_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0004335 47.0
DTH3_k127_8412216_0 PFAM Heat shock protein DnaJ, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 424.0
DTH3_k127_8412216_1 PFAM RNA polymerase sigma factor 70, region 4 type 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 311.0
DTH3_k127_8412216_2 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000000000000000000000001387 162.0
DTH3_k127_8412216_3 Protein of unknown function (DUF3619) - - - 0.000000000000000000000000001303 115.0
DTH3_k127_8422767_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.569e-264 816.0
DTH3_k127_8422767_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 493.0
DTH3_k127_8422767_2 - - - - 0.000000000000000000000000000000000000000000000000008947 183.0
DTH3_k127_8423165_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1004.0
DTH3_k127_8423165_1 Copper binding periplasmic protein CusF K07798,K15727 - - 2.26e-237 743.0
DTH3_k127_8423165_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 1.885e-218 680.0
DTH3_k127_8423165_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 555.0
DTH3_k127_8423165_4 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 519.0
DTH3_k127_8423165_5 - - - - 0.00000000000000000000000000000000000004875 145.0
DTH3_k127_8423165_6 Domain of unknown function (DUF3362) - - - 0.000004886 48.0
DTH3_k127_8445007_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 8.33e-281 868.0
DTH3_k127_8445007_1 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 501.0
DTH3_k127_8445007_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 378.0
DTH3_k127_8445007_3 Putative DNA-binding domain K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005681 284.0
DTH3_k127_8445007_4 - - - - 0.000000000000000000000000000000000000000001268 157.0
DTH3_k127_8445007_5 - - - - 0.000000000000000000000000000000000000005771 149.0
DTH3_k127_8445007_6 Histidine kinase-like ATPases - - - 0.000000000000000000000004708 104.0
DTH3_k127_850805_0 PFAM Integrase, catalytic core - - - 8.664e-248 773.0
DTH3_k127_850805_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 366.0
DTH3_k127_8599082_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 3.293e-237 744.0
DTH3_k127_8599082_1 Sigma-54 interaction domain K02667 - - 1.528e-235 735.0
DTH3_k127_8599082_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 497.0
DTH3_k127_8599082_3 - K06950 - - 0.00000000000000000000003824 100.0
DTH3_k127_8599082_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000001321 70.0
DTH3_k127_8607950_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 2.462e-250 775.0
DTH3_k127_8607950_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 6.564e-214 668.0
DTH3_k127_8607950_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 583.0
DTH3_k127_8607950_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 401.0
DTH3_k127_8607950_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 394.0
DTH3_k127_8607950_5 CreA protein K05805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
DTH3_k127_8607950_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000001746 209.0
DTH3_k127_8607950_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000003678 158.0
DTH3_k127_8635710_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.093e-285 882.0
DTH3_k127_8635710_1 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000000000000025 171.0
DTH3_k127_8635710_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000001202 163.0
DTH3_k127_8635710_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000004866 110.0
DTH3_k127_8678989_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1825.0
DTH3_k127_8679542_0 ISXO2-like transposase domain K07488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 431.0
DTH3_k127_8679542_1 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
DTH3_k127_8679542_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000001663 203.0
DTH3_k127_8690567_0 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 527.0
DTH3_k127_8690567_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 498.0
DTH3_k127_8690567_2 Membrane fusogenic activity K09806 - - 0.000000000000000000000000000000006973 130.0
DTH3_k127_8690567_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000002943 104.0
DTH3_k127_8690567_4 Domain of unknown function (DUF3362) - - - 0.00001756 47.0
DTH3_k127_8712753_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.027e-263 814.0
DTH3_k127_8712753_1 Belongs to the ClpA ClpB family K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 426.0
DTH3_k127_8712753_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 308.0
DTH3_k127_8712753_3 Domain of unknown function (DUF3362) - - - 0.0000000009374 59.0
DTH3_k127_8786454_0 50S ribosome-binding GTPase K06946 - - 2.847e-258 803.0
DTH3_k127_8786454_1 Domain of unknown function (DUF697) - - - 4.415e-204 641.0
DTH3_k127_8786454_2 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000008459 116.0
DTH3_k127_8803481_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 472.0
DTH3_k127_8803481_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000001235 183.0
DTH3_k127_8803481_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000003941 132.0
DTH3_k127_8803572_0 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 340.0
DTH3_k127_8803572_1 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 286.0
DTH3_k127_8803572_2 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000001344 169.0
DTH3_k127_8803572_3 PFAM Integrase, catalytic core, phage - - - 0.00000000001324 64.0
DTH3_k127_8803572_5 - - - - 0.0006046 45.0
DTH3_k127_8805150_0 CoA-binding domain K01710,K15894 - 4.2.1.115,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 317.0
DTH3_k127_8805150_1 Glycosyl transferase family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 306.0
DTH3_k127_8805150_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 307.0
DTH3_k127_881074_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.525e-244 756.0
DTH3_k127_881074_1 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000704 160.0
DTH3_k127_881074_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000001687 67.0
DTH3_k127_8812096_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1400.0
DTH3_k127_8812096_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.348e-255 794.0
DTH3_k127_8812096_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 9.423e-213 662.0
DTH3_k127_8812096_3 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000002567 189.0
DTH3_k127_8828321_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 1.408e-205 642.0
DTH3_k127_8828321_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001416 267.0
DTH3_k127_8828321_2 NlpC/P60 family K13695,K19303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003035 249.0
DTH3_k127_8828321_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000008766 124.0
DTH3_k127_8859361_0 Histidine kinase K20974 - 2.7.13.3 0.0 1047.0
DTH3_k127_8859361_1 - - - - 0.00000000000000000000000001252 115.0
DTH3_k127_8883954_0 Domain of unknown function DUF21 - - - 1.766e-243 755.0
DTH3_k127_8883954_1 Predicted small integral membrane protein (DUF2165) - - - 0.00000000000000000000000000000000000000000000000000000000000000000141 229.0
DTH3_k127_8950265_0 HflC and HflK could encode or regulate a protease K04088 - - 2.433e-231 718.0
DTH3_k127_8950265_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000001372 194.0
DTH3_k127_8950921_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 0.0 1037.0
DTH3_k127_8950921_1 - - - - 0.0000000000000000000000000000000000000000000000000000000009436 207.0
DTH3_k127_8982275_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.144e-224 704.0
DTH3_k127_8982275_1 repeat protein - - - 2.847e-215 674.0
DTH3_k127_9048563_0 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 608.0
DTH3_k127_9048563_1 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 402.0
DTH3_k127_9048563_2 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000002728 139.0
DTH3_k127_9082238_0 glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 451.0
DTH3_k127_9082238_1 Protoglobin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 394.0
DTH3_k127_9082238_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000001767 192.0
DTH3_k127_9082238_3 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.000000000000000000000000000000002256 140.0
DTH3_k127_9082238_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000002038 59.0
DTH3_k127_9092978_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.155e-247 767.0
DTH3_k127_9092978_1 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
DTH3_k127_9092978_2 Putative restriction endonuclease - - - 0.00000000000000005504 82.0
DTH3_k127_9131284_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1205.0
DTH3_k127_9131284_1 Belongs to the GPI family K01810 - 5.3.1.9 4.624e-238 742.0
DTH3_k127_9155013_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 488.0
DTH3_k127_9155013_1 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 287.0
DTH3_k127_9155013_2 SMART ATPase, AAA type, core K06148 - - 0.000000000000000000002195 93.0
DTH3_k127_9170153_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 582.0
DTH3_k127_9170153_1 low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003144 272.0
DTH3_k127_9170153_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000002788 106.0
DTH3_k127_9183602_0 Signal transduction histidine kinase K07637 - 2.7.13.3 1.151e-224 702.0
DTH3_k127_9183602_1 family UPF0016 - - - 0.00000000000000000000000000000000000002527 145.0
DTH3_k127_9183602_2 PFAM Signal transduction response regulator, receiver K07660 - - 0.0000000000000000000000000000000000002948 140.0
DTH3_k127_91932_0 protein synthesis factor, GTP-binding K06207 - - 0.0 1046.0
DTH3_k127_91932_1 GTP-binding protein, HSR1-related - - - 4.503e-259 804.0
DTH3_k127_91932_2 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000001919 200.0
DTH3_k127_9201465_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 397.0
DTH3_k127_9201465_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 336.0
DTH3_k127_9201465_2 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000000000000000000000005796 203.0
DTH3_k127_9206114_0 SMART Diguanylate phosphodiesterase - - - 5.051e-202 651.0
DTH3_k127_9206114_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 473.0
DTH3_k127_9206114_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 426.0
DTH3_k127_9206114_3 COG2202 FOG PAS PAC domain K03406,K07315 - 3.1.3.3 0.00000000000000000000000006093 110.0
DTH3_k127_9233133_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0 1032.0
DTH3_k127_9233133_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 452.0
DTH3_k127_9261065_0 pdz dhr glgf - - - 0.0 1656.0
DTH3_k127_9265963_0 DNA mismatch repair protein MutS - - - 1.438e-271 842.0
DTH3_k127_9265963_1 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002188 275.0
DTH3_k127_9265963_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000007094 208.0
DTH3_k127_9299453_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 388.0
DTH3_k127_9299453_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 336.0
DTH3_k127_9299453_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002024 268.0
DTH3_k127_9308424_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 563.0
DTH3_k127_9308424_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000002674 185.0
DTH3_k127_9308424_2 - - - - 0.0000000000000000000000000000000004751 131.0
DTH3_k127_930938_0 Domain of unknown function (DUF3463) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 595.0
DTH3_k127_930938_1 glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
DTH3_k127_930938_2 Domain of unknown function (DUF3362) - - - 0.000006783 49.0
DTH3_k127_932418_0 Tetratricopeptide repeat - - - 8.807e-301 931.0
DTH3_k127_932418_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 499.0
DTH3_k127_932418_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 400.0
DTH3_k127_932418_3 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 298.0
DTH3_k127_9336778_0 PFAM Peptidase S45, penicillin amidase K01434 - 3.5.1.11 1.26e-269 839.0
DTH3_k127_933690_0 Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor K03406,K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 312.0
DTH3_k127_933690_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 310.0
DTH3_k127_9364619_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.557e-206 644.0
DTH3_k127_9364619_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 513.0
DTH3_k127_9364619_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 490.0
DTH3_k127_9368971_0 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000004545 216.0
DTH3_k127_9368971_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
DTH3_k127_9368971_2 ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000003553 183.0
DTH3_k127_9368971_3 Diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000001936 158.0
DTH3_k127_9368971_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000005166 48.0
DTH3_k127_9373946_0 Signal transduction response regulator, receiver K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 520.0
DTH3_k127_9373946_1 - - - - 0.000000000000000000000000002547 111.0
DTH3_k127_9373946_2 CAAX protease self-immunity - - - 0.0000000000000000000002144 96.0
DTH3_k127_9400467_0 TIGRFAM type I restriction system adenine methylase (hsdM) K03427 - 2.1.1.72 2.734e-222 692.0
DTH3_k127_9400467_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 409.0
DTH3_k127_9400467_2 PFAM Integrase, catalytic region - - - 0.000000000000008361 74.0
DTH3_k127_9400467_3 Domain of unknown function (DUF3362) - - - 0.00000001203 56.0
DTH3_k127_9428320_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1182.0
DTH3_k127_9428320_1 signal recognition particle SRP54 K02404 - - 3.922e-206 647.0
DTH3_k127_9428320_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 584.0
DTH3_k127_9428320_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 426.0
DTH3_k127_9428320_4 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 346.0
DTH3_k127_970734_0 PFAM Peptidase M48 - - - 6.09e-220 689.0
DTH3_k127_970734_1 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000002777 126.0
DTH3_k127_972013_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 4.201e-285 880.0
DTH3_k127_980629_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 499.0
DTH3_k127_980629_1 PFAM Type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000005755 227.0
DTH3_k127_980629_2 - - - - 0.000000000000000000000000000000000000000000006053 168.0
DTH3_k127_980629_3 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000002258 138.0
DTH3_k127_980629_4 - - - - 0.00000000000315 70.0
DTH3_k127_980629_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 0.0001278 45.0
DTH3_k127_98099_0 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 288.0
DTH3_k127_98099_1 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000000000000000000000000000006936 199.0
DTH3_k127_98099_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000002521 179.0
DTH3_k127_98099_3 HPr Serine kinase N terminus K06023 - - 0.0000000000008957 71.0
DTH3_k127_98099_4 Domain of unknown function (DUF3362) - - - 0.00001821 46.0