Overview

ID MAG00905
Name DYD2_bin.22
Sample SMP0026
Taxonomy
Kingdom Bacteria
Phylum Patescibacteriota
Class Patescibacteriia
Order SG8-24
Family DYFX01
Genus DYFX01
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 2.49
GC content (%) 66.0
N50 (bp) 23,577
Genome size (bp) 1,368,350

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes928

Gene name Description KEGG GOs EC E-value Score Sequence
DYD2_k127_1136757_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 506.0
DYD2_k127_1136757_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 491.0
DYD2_k127_1136757_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006047 90.0
DYD2_k127_1136757_11 AAA domain K00859 - 2.7.1.24 0.00000000000005249 83.0
DYD2_k127_1136757_12 - - - - 0.0000000001217 63.0
DYD2_k127_1136757_13 Diguanylate cyclase - - - 0.000003043 61.0
DYD2_k127_1136757_14 Protein of unknown function (DUF3137) - - - 0.00001791 56.0
DYD2_k127_1136757_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 425.0
DYD2_k127_1136757_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 350.0
DYD2_k127_1136757_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000007321 262.0
DYD2_k127_1136757_5 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001008 262.0
DYD2_k127_1136757_6 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001312 251.0
DYD2_k127_1136757_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000003864 176.0
DYD2_k127_1136757_8 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000004361 151.0
DYD2_k127_1136757_9 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.0000000000000000000000000000000001182 138.0
DYD2_k127_1146526_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 337.0
DYD2_k127_1284606_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 357.0
DYD2_k127_1284606_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000007843 212.0
DYD2_k127_1284606_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000004724 114.0
DYD2_k127_1284606_3 PAP2 superfamily - - - 0.0000000000000114 82.0
DYD2_k127_1284606_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000003393 57.0
DYD2_k127_1309687_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 586.0
DYD2_k127_1309687_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 392.0
DYD2_k127_1309687_10 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000002585 143.0
DYD2_k127_1309687_11 Belongs to the universal ribosomal protein uS5 family K02988 GO:0000313,GO:0000314,GO:0003002,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0007275,GO:0007389,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009657,GO:0009955,GO:0009987,GO:0010035,GO:0010038,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0031974,GO:0031976,GO:0031984,GO:0032501,GO:0032502,GO:0032544,GO:0032991,GO:0034357,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042221,GO:0042254,GO:0042651,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0048856,GO:0050896,GO:0055035,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0098798,GO:1901259,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000459 149.0
DYD2_k127_1309687_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000001343 134.0
DYD2_k127_1309687_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000003107 128.0
DYD2_k127_1309687_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000001375 123.0
DYD2_k127_1309687_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001691 120.0
DYD2_k127_1309687_16 - - - - 0.0000000000000000000000000006977 122.0
DYD2_k127_1309687_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000461 114.0
DYD2_k127_1309687_18 Binds to the 23S rRNA K02876 - - 0.000000000000000000001231 100.0
DYD2_k127_1309687_19 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001663 96.0
DYD2_k127_1309687_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 327.0
DYD2_k127_1309687_20 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000007243 93.0
DYD2_k127_1309687_21 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000001046 89.0
DYD2_k127_1309687_22 - - - - 0.0000000009612 71.0
DYD2_k127_1309687_23 Histidine kinase K15011 - 2.7.13.3 0.000001045 50.0
DYD2_k127_1309687_24 MotA/TolQ/ExbB proton channel family - - - 0.00001001 55.0
DYD2_k127_1309687_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005868 219.0
DYD2_k127_1309687_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004971 202.0
DYD2_k127_1309687_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
DYD2_k127_1309687_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000008974 197.0
DYD2_k127_1309687_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000001544 179.0
DYD2_k127_1309687_8 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000001115 169.0
DYD2_k127_1309687_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000001733 164.0
DYD2_k127_1349169_0 Conserved repeat domain - - - 0.0000000000000000000000001799 118.0
DYD2_k127_1388356_0 Histidine kinase - - - 0.00000000008844 73.0
DYD2_k127_1419683_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 561.0
DYD2_k127_1419683_1 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 415.0
DYD2_k127_1419683_2 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001531 274.0
DYD2_k127_1419683_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000004365 152.0
DYD2_k127_1419683_4 cheY-homologous receiver domain K03407,K03413 - 2.7.13.3 0.000000000000000000005283 98.0
DYD2_k127_1419683_5 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000006096 66.0
DYD2_k127_1419683_6 Prokaryotic N-terminal methylation motif - - - 0.00000008388 60.0
DYD2_k127_1419683_7 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.0002886 51.0
DYD2_k127_1419683_8 Protein of unknown function (DUF1559) K02456 - - 0.0009356 49.0
DYD2_k127_1463910_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 8.12e-230 730.0
DYD2_k127_1463910_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835,K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 368.0
DYD2_k127_1463910_10 Vitamin K epoxide reductase - - - 0.0000000000000004262 83.0
DYD2_k127_1463910_11 Belongs to the UPF0200 family - - - 0.000004655 57.0
DYD2_k127_1463910_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001179 264.0
DYD2_k127_1463910_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000001189 235.0
DYD2_k127_1463910_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000003138 237.0
DYD2_k127_1463910_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000002514 174.0
DYD2_k127_1463910_6 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000000002661 136.0
DYD2_k127_1463910_7 Nucleotidyl transferase - - - 0.0000000000000000000000000000001292 132.0
DYD2_k127_1463910_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000008513 125.0
DYD2_k127_1463910_9 Binds the 23S rRNA K02909 - - 0.0000000000000000000000004908 107.0
DYD2_k127_1465848_0 Flotillin K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000002466 206.0
DYD2_k127_1465848_1 Histidine kinase K07652 - 2.7.13.3 0.00000000000000000001517 94.0
DYD2_k127_1467158_0 tail collar domain protein - - - 0.00000000000000000000000009414 124.0
DYD2_k127_1467158_1 to other proteins from the same organism - - - 0.00009619 55.0
DYD2_k127_1497142_0 phosphatidylethanolamine binding - - - 0.000000000000000003411 102.0
DYD2_k127_1497142_1 self proteolysis K07156 - - 0.000000001708 73.0
DYD2_k127_1559073_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 507.0
DYD2_k127_1559073_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 445.0
DYD2_k127_1559073_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000009479 83.0
DYD2_k127_1559073_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 344.0
DYD2_k127_1559073_3 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000003043 217.0
DYD2_k127_1559073_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000003743 210.0
DYD2_k127_1559073_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000001621 146.0
DYD2_k127_1559073_7 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000002531 115.0
DYD2_k127_1559073_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000001367 92.0
DYD2_k127_1559073_9 - - - - 0.000000000000000005589 90.0
DYD2_k127_1648460_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 368.0
DYD2_k127_1648460_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000001366 207.0
DYD2_k127_1648460_2 Hep Hag repeat protein - - - 0.0000000000000004472 93.0
DYD2_k127_1648460_3 sugar transferase - - - 0.0000000000003424 70.0
DYD2_k127_1648460_4 Peptidase family M23 - - - 0.000000000000649 82.0
DYD2_k127_1648460_5 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000004472 60.0
DYD2_k127_1725068_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.589e-320 1002.0
DYD2_k127_1725068_1 nucleotide-excision repair K03702,K08999 - - 1.499e-257 812.0
DYD2_k127_1725068_10 PFAM NAD dependent epimerase dehydratase family K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
DYD2_k127_1725068_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000004912 270.0
DYD2_k127_1725068_12 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000779 269.0
DYD2_k127_1725068_13 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000001513 234.0
DYD2_k127_1725068_14 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000008805 225.0
DYD2_k127_1725068_15 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000005906 219.0
DYD2_k127_1725068_16 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000001658 206.0
DYD2_k127_1725068_17 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000001958 216.0
DYD2_k127_1725068_18 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000002828 191.0
DYD2_k127_1725068_19 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000008074 179.0
DYD2_k127_1725068_2 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 629.0
DYD2_k127_1725068_20 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000001114 181.0
DYD2_k127_1725068_21 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000003389 159.0
DYD2_k127_1725068_22 Glycosyltransferase Family 4 K19424 - - 0.0000000000000000000000000000000002669 148.0
DYD2_k127_1725068_23 VIT family - - - 0.000000000000000000000000000000003332 138.0
DYD2_k127_1725068_24 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000109 126.0
DYD2_k127_1725068_25 MazG nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000005967 126.0
DYD2_k127_1725068_26 acr, cog1430 K09005 - - 0.0000000000000000000001787 103.0
DYD2_k127_1725068_27 belongs to the sigma-70 factor family - - - 0.00000000000000000002486 102.0
DYD2_k127_1725068_28 diguanylate cyclase - - - 0.0000000000000000004399 100.0
DYD2_k127_1725068_29 Major Facilitator - - - 0.000000000000000001618 98.0
DYD2_k127_1725068_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 536.0
DYD2_k127_1725068_30 tRNA (uracil-5-)-methyltransferase TRM9 K15444 GO:0000049,GO:0001300,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006448,GO:0006725,GO:0006807,GO:0007568,GO:0007569,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0009451,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016300,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0019222,GO:0030488,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0032502,GO:0034248,GO:0034470,GO:0034641,GO:0034660,GO:0035690,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051213,GO:0051246,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0070887,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:2000112 2.1.1.229 0.00000000000002901 83.0
DYD2_k127_1725068_31 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000093 79.0
DYD2_k127_1725068_32 Belongs to the AAA ATPase family - - - 0.000000000001244 76.0
DYD2_k127_1725068_33 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000009745 74.0
DYD2_k127_1725068_34 - - - - 0.00000000001478 76.0
DYD2_k127_1725068_35 Transmembrane amino acid transporter protein - - - 0.00000000002156 76.0
DYD2_k127_1725068_36 -O-antigen - - - 0.00000000003814 78.0
DYD2_k127_1725068_37 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000001073 60.0
DYD2_k127_1725068_38 Domain of unknown function (DUF378) K09779 - - 0.00000003783 59.0
DYD2_k127_1725068_39 PGAP1-like protein - - - 0.00000004685 62.0
DYD2_k127_1725068_4 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 440.0
DYD2_k127_1725068_40 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000002324 63.0
DYD2_k127_1725068_41 sister chromatid segregation - - - 0.000008418 55.0
DYD2_k127_1725068_42 Fic/DOC family - - - 0.00003095 56.0
DYD2_k127_1725068_43 peptidyl-tyrosine sulfation - - - 0.0005224 49.0
DYD2_k127_1725068_5 PFAM UMUC domain protein DNA-repair protein K02346,K03502 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 377.0
DYD2_k127_1725068_6 exonuclease of the beta-lactamase fold involved in RNA K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 356.0
DYD2_k127_1725068_7 beta-glucosidase activity K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 346.0
DYD2_k127_1725068_8 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 292.0
DYD2_k127_1725068_9 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007934 283.0
DYD2_k127_1762195_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 415.0
DYD2_k127_1762195_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 415.0
DYD2_k127_1762195_10 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000006067 188.0
DYD2_k127_1762195_11 - - - - 0.000000000000000000000000000000000000000000008324 169.0
DYD2_k127_1762195_12 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000009418 153.0
DYD2_k127_1762195_13 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000001148 153.0
DYD2_k127_1762195_14 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000002051 156.0
DYD2_k127_1762195_15 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000003255 149.0
DYD2_k127_1762195_16 His Kinase A (phosphoacceptor) domain K19694 - - 0.000000000000000000000000000000000007149 151.0
DYD2_k127_1762195_17 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000002556 139.0
DYD2_k127_1762195_18 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000001568 115.0
DYD2_k127_1762195_19 Yqey-like protein K09117 - - 0.000000000000000000000000002813 117.0
DYD2_k127_1762195_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 360.0
DYD2_k127_1762195_20 - - - - 0.0000000000000000000000001133 111.0
DYD2_k127_1762195_21 Belongs to the BI1 family K06890 - - 0.000000000000000000000001074 113.0
DYD2_k127_1762195_22 uridine kinase K00876 - 2.7.1.48 0.00000000000000000000001377 111.0
DYD2_k127_1762195_23 glutamine amidotransferase K01951 - 6.3.5.2 0.000000000000000000001631 109.0
DYD2_k127_1762195_24 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000001284 100.0
DYD2_k127_1762195_25 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000001161 84.0
DYD2_k127_1762195_27 domain protein K20276 - - 0.000000000000131 84.0
DYD2_k127_1762195_28 Belongs to the peptidase S8 family - - - 0.0000000001675 69.0
DYD2_k127_1762195_29 von Willebrand factor type A domain - - - 0.000000003923 66.0
DYD2_k127_1762195_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K00058,K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 343.0
DYD2_k127_1762195_30 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00004649 48.0
DYD2_k127_1762195_31 domain, Protein K13714 - 3.2.1.96,3.5.1.28 0.0001519 53.0
DYD2_k127_1762195_32 DNA protecting protein DprA K04096 - - 0.0003617 44.0
DYD2_k127_1762195_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 327.0
DYD2_k127_1762195_5 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000001825 240.0
DYD2_k127_1762195_6 Domain of unknown function (DUF4166) - - - 0.0000000000000000000000000000000000000000000000000000000003732 212.0
DYD2_k127_1762195_7 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000006534 213.0
DYD2_k127_1762195_8 YibE/F-like protein - - - 0.0000000000000000000000000000000000000000000000000000001982 210.0
DYD2_k127_1762195_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000003887 196.0
DYD2_k127_1781355_0 Pfam SNARE associated Golgi protein K03975 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000001741 244.0
DYD2_k127_1781355_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000002456 188.0
DYD2_k127_1822105_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 310.0
DYD2_k127_1822105_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000004161 81.0
DYD2_k127_1822105_2 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.00000008406 56.0
DYD2_k127_1946628_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.698e-266 850.0
DYD2_k127_1946628_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0000166,GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005488,GO:0006082,GO:0006103,GO:0006520,GO:0006536,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0022607,GO:0034214,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051259,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070402,GO:0070403,GO:0070404,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 396.0
DYD2_k127_1946628_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000005619 168.0
DYD2_k127_1946628_3 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000001718 154.0
DYD2_k127_1946628_4 ComEC Rec2-related protein K02238 - - 0.000000000000000000000001318 116.0
DYD2_k127_1946628_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000003128 61.0
DYD2_k127_1946628_6 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00002192 55.0
DYD2_k127_2031542_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 351.0
DYD2_k127_2031542_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009049 257.0
DYD2_k127_2031542_3 self proteolysis - - - 0.00000000000000000000000000002717 136.0
DYD2_k127_2031542_4 Glycosyl transferases group 1 - - - 0.0000000000000000000004403 100.0
DYD2_k127_2031542_5 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000002248 93.0
DYD2_k127_2031542_6 - - - - 0.0000001179 63.0
DYD2_k127_2033304_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.848e-220 711.0
DYD2_k127_2033304_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
DYD2_k127_2034185_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007561 287.0
DYD2_k127_2034185_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000518 169.0
DYD2_k127_2051780_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003889 293.0
DYD2_k127_2064565_0 cell adhesion K11904 - - 0.0000007423 60.0
DYD2_k127_2249164_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004467 249.0
DYD2_k127_2249164_1 Sortase family K07284,K22278 - 3.4.22.70,3.5.1.104 0.000000000000000000000000002648 121.0
DYD2_k127_2249164_2 Peptidase family M23 K21472 - - 0.00000000000000000009982 100.0
DYD2_k127_2249164_3 alginic acid biosynthetic process K20276 - - 0.0000000000000007548 91.0
DYD2_k127_2249164_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000009983 91.0
DYD2_k127_2249164_5 lactoylglutathione lyase activity - - - 0.000008774 50.0
DYD2_k127_2256065_0 surface antigen - - - 0.00000000006026 78.0
DYD2_k127_2256065_1 Collagen triple helix repeat (20 copies) - - - 0.000000008419 71.0
DYD2_k127_2256074_0 Hep Hag repeat protein K01406 - 3.4.24.40 0.0003831 54.0
DYD2_k127_2343094_0 Glycosyl transferase, WecB TagA CpsF family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000001153 192.0
DYD2_k127_2343094_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000005449 175.0
DYD2_k127_2343094_2 Cupredoxin-like domain - - - 0.0000004717 61.0
DYD2_k127_2350911_0 metallopeptidase activity K00571,K01126,K01176 - 2.1.1.72,3.1.4.46,3.2.1.1 0.000000000000000000000000000005001 141.0
DYD2_k127_2350911_1 alginic acid biosynthetic process K21449 - - 0.00009355 57.0
DYD2_k127_2371452_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 7.737e-207 650.0
DYD2_k127_2441226_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 362.0
DYD2_k127_2441226_1 Bacterial protein of unknown function (DUF916) - - - 0.00000000000001543 85.0
DYD2_k127_2441226_2 Bacterial protein of unknown function (DUF916) - - - 0.00000000009715 73.0
DYD2_k127_2556797_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 616.0
DYD2_k127_2556797_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 475.0
DYD2_k127_2556797_10 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000001358 113.0
DYD2_k127_2556797_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000005062 92.0
DYD2_k127_2556797_12 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.000000000000000005508 91.0
DYD2_k127_2556797_13 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000003622 87.0
DYD2_k127_2556797_14 - - - - 0.0000000009634 69.0
DYD2_k127_2556797_15 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000001185 64.0
DYD2_k127_2556797_16 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0003011 52.0
DYD2_k127_2556797_2 Cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 372.0
DYD2_k127_2556797_3 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 379.0
DYD2_k127_2556797_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 359.0
DYD2_k127_2556797_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 334.0
DYD2_k127_2556797_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 314.0
DYD2_k127_2556797_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000007643 130.0
DYD2_k127_2556797_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000009084 132.0
DYD2_k127_2556797_9 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000003195 126.0
DYD2_k127_2582841_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 467.0
DYD2_k127_2582841_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 448.0
DYD2_k127_2582841_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 453.0
DYD2_k127_2582841_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 378.0
DYD2_k127_2582841_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 333.0
DYD2_k127_2582841_5 Pyridine nucleotide-disulphide oxidoreductase K03885 GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 0.000000000000000000000000000000000000000000002298 181.0
DYD2_k127_2582841_6 metallophosphoesterase K07098 - - 0.000000000000000000000000000000000002753 154.0
DYD2_k127_2582841_7 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000002062 140.0
DYD2_k127_25936_0 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.945e-271 852.0
DYD2_k127_25936_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 569.0
DYD2_k127_25936_10 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000004171 188.0
DYD2_k127_25936_11 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000001883 182.0
DYD2_k127_25936_12 7,8-dihydro-8-oxoguanine triphosphatase K03574,K17816 GO:0000003,GO:0001669,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006259,GO:0006281,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0007154,GO:0007275,GO:0007548,GO:0007568,GO:0008150,GO:0008152,GO:0008406,GO:0008413,GO:0008584,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0012505,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022414,GO:0030141,GO:0030515,GO:0031090,GO:0031410,GO:0031668,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032501,GO:0032502,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0036219,GO:0042221,GO:0042262,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044713,GO:0044714,GO:0045137,GO:0046060,GO:0046061,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046546,GO:0046661,GO:0046686,GO:0046700,GO:0047429,GO:0047693,GO:0048513,GO:0048608,GO:0048731,GO:0048856,GO:0050896,GO:0051716,GO:0055086,GO:0061458,GO:0070013,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0090304,GO:0097159,GO:0097223,GO:0097708,GO:0099503,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.6.1.55,3.6.1.56 0.000000000000000000000000000000000000000000000001218 179.0
DYD2_k127_25936_13 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000004823 177.0
DYD2_k127_25936_14 fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000002361 166.0
DYD2_k127_25936_15 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000219 155.0
DYD2_k127_25936_16 Cupin domain - - - 0.000000000000000000000000000000000002339 141.0
DYD2_k127_25936_17 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000009116 143.0
DYD2_k127_25936_18 Cupin domain - - - 0.0000000000000000000000000000001685 139.0
DYD2_k127_25936_19 DoxX K16937 - 1.8.5.2 0.00000000000000000000000002561 114.0
DYD2_k127_25936_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 551.0
DYD2_k127_25936_20 - - - - 0.0000000000000000000000008354 116.0
DYD2_k127_25936_21 alpha-ribazole phosphatase activity K02226,K07814 - 3.1.3.73 0.0000000000000000000000008466 115.0
DYD2_k127_25936_22 Conserved repeat domain - - - 0.00000000000000000000000204 120.0
DYD2_k127_25936_23 - - - - 0.00000000000000000000006706 103.0
DYD2_k127_25936_24 Peptidase S24-like K03503 - - 0.00000000000000000001072 96.0
DYD2_k127_25936_25 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000001642 98.0
DYD2_k127_25936_26 Immunoglobulin-like domain of bacterial spore germination - - - 0.00000000000000000001757 97.0
DYD2_k127_25936_27 - - - - 0.0000000000000000003847 98.0
DYD2_k127_25936_28 bis(5'-adenosyl)-triphosphatase activity K01518 - 3.6.1.17 0.0000000000000000008581 94.0
DYD2_k127_25936_29 Cysteine-rich secretory protein family - - - 0.000000000000000001488 98.0
DYD2_k127_25936_3 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 464.0
DYD2_k127_25936_30 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000006414 87.0
DYD2_k127_25936_31 C-terminal domain of CHU protein family - - - 0.00000000000000002011 98.0
DYD2_k127_25936_32 YGGT family - - - 0.0000000000000006154 87.0
DYD2_k127_25936_33 Putative ABC-transporter type IV - - - 0.000000000000001058 89.0
DYD2_k127_25936_34 pilus organization - - - 0.0000000000002419 84.0
DYD2_k127_25936_35 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000009745 74.0
DYD2_k127_25936_36 Protein of unknown function (DUF1152) - - - 0.0000001941 64.0
DYD2_k127_25936_37 pantothenate kinase activity K09680 - 2.7.1.33 0.0000004815 61.0
DYD2_k127_25936_38 Sortase (surface protein transpeptidase) K07284 - 3.4.22.70 0.00002782 56.0
DYD2_k127_25936_39 Protein of unknown function (DUF1559) - - - 0.00041 49.0
DYD2_k127_25936_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 301.0
DYD2_k127_25936_5 Nucleoside 2-deoxyribosyltransferase like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003088 289.0
DYD2_k127_25936_6 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001246 285.0
DYD2_k127_25936_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000002468 255.0
DYD2_k127_25936_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000169 207.0
DYD2_k127_2599066_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.451e-222 711.0
DYD2_k127_2599066_1 Asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 542.0
DYD2_k127_2599066_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000003757 163.0
DYD2_k127_2599066_11 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000002815 149.0
DYD2_k127_2599066_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000006778 132.0
DYD2_k127_2599066_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000001026 120.0
DYD2_k127_2599066_14 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000002775 101.0
DYD2_k127_2599066_15 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000002294 89.0
DYD2_k127_2599066_16 Putative metal-binding motif - - - 0.0000000000000001361 93.0
DYD2_k127_2599066_17 Aminoacyl-tRNA editing domain K19055 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000006821 64.0
DYD2_k127_2599066_19 SMART Peptidase A22, presenilin signal peptide - - - 0.0001568 53.0
DYD2_k127_2599066_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 514.0
DYD2_k127_2599066_20 Encoded by K10408 - - 0.0005311 42.0
DYD2_k127_2599066_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 478.0
DYD2_k127_2599066_4 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 289.0
DYD2_k127_2599066_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000008578 239.0
DYD2_k127_2599066_6 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000002377 231.0
DYD2_k127_2599066_7 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001259 227.0
DYD2_k127_2599066_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000001443 217.0
DYD2_k127_2599066_9 PAS domain - - - 0.00000000000000000000000000000000000000000000000001578 194.0
DYD2_k127_2701042_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 366.0
DYD2_k127_2701042_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 332.0
DYD2_k127_2701042_10 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000046 113.0
DYD2_k127_2701042_11 Metal binding domain of Ada K00567 - 2.1.1.63 0.000000000000000000001073 100.0
DYD2_k127_2701042_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000003507 261.0
DYD2_k127_2701042_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000001152 198.0
DYD2_k127_2701042_4 Dienelactone hydrolase family K07100 - - 0.000000000000000000000000000000000000000000000000003206 192.0
DYD2_k127_2701042_5 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000001572 181.0
DYD2_k127_2701042_6 - - - - 0.000000000000000000000000000000000000000000004022 184.0
DYD2_k127_2701042_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000004496 141.0
DYD2_k127_2701042_8 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000001801 135.0
DYD2_k127_2701042_9 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000008133 140.0
DYD2_k127_272377_0 arginyl-trna synthetase - - - 0.00000000000000000001177 109.0
DYD2_k127_2790157_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 1202.0
DYD2_k127_2790157_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1193.0
DYD2_k127_2790157_10 Putative RNA methylase family UPF0020 - - - 0.0000000000000000000000000889 124.0
DYD2_k127_2790157_11 Fibronectin type III domain - - - 0.000000000000000000000001548 121.0
DYD2_k127_2790157_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002585 92.0
DYD2_k127_2790157_13 - - - - 0.00000000000000007389 84.0
DYD2_k127_2790157_14 Protein of unknown function (DUF1761) - - - 0.000000000000001917 81.0
DYD2_k127_2790157_15 Tetratricopeptide TPR_2 repeat protein - - - 0.00000009036 66.0
DYD2_k127_2790157_16 SMART helix-turn-helix domain protein K15539 - - 0.000009376 56.0
DYD2_k127_2790157_17 Domain of unknown function (DUF4397) - - - 0.00001032 58.0
DYD2_k127_2790157_18 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00001247 53.0
DYD2_k127_2790157_19 - - - - 0.00003284 54.0
DYD2_k127_2790157_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 494.0
DYD2_k127_2790157_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 443.0
DYD2_k127_2790157_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 411.0
DYD2_k127_2790157_5 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 323.0
DYD2_k127_2790157_6 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006982 286.0
DYD2_k127_2790157_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000005392 198.0
DYD2_k127_2790157_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000004762 134.0
DYD2_k127_2790157_9 WD40 repeat, subgroup - - - 0.000000000000000000000000006934 127.0
DYD2_k127_2798897_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0008608 51.0
DYD2_k127_2854097_1 YadA-like membrane anchor domain K12342 - - 0.000000000001228 83.0
DYD2_k127_2854097_2 tail collar domain protein - - - 0.000000001173 74.0
DYD2_k127_2856195_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
DYD2_k127_2856195_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 285.0
DYD2_k127_2856195_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002935 271.0
DYD2_k127_2856195_3 domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000006709 181.0
DYD2_k127_2856195_4 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000001072 96.0
DYD2_k127_2856195_5 Putative amidase domain - - - 0.00000000000009223 84.0
DYD2_k127_2856195_6 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000005114 78.0
DYD2_k127_2856195_7 KH domain K06960 - - 0.0000000000005683 80.0
DYD2_k127_2887488_0 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000001496 119.0
DYD2_k127_2887488_1 membrane protein, required for colicin V production - - - 0.000001224 59.0
DYD2_k127_2891444_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000001063 222.0
DYD2_k127_2891737_0 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000007418 262.0
DYD2_k127_2891737_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000002151 192.0
DYD2_k127_2891737_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000003191 76.0
DYD2_k127_2923952_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 351.0
DYD2_k127_3108034_0 Methyltransferase - - - 0.000000009939 64.0
DYD2_k127_3108034_1 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000007482 53.0
DYD2_k127_3132777_0 Heat shock 70 kDa protein K04043 - - 1.771e-249 784.0
DYD2_k127_3132777_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 2.01e-201 660.0
DYD2_k127_3132777_10 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000005906 196.0
DYD2_k127_3132777_11 DEAD DEAH box helicase domain protein K06877 - - 0.0000000000000000000000000000001396 131.0
DYD2_k127_3132777_12 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000001201 115.0
DYD2_k127_3132777_13 cellulose binding - - - 0.0000000000000000000002222 115.0
DYD2_k127_3132777_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000002217 98.0
DYD2_k127_3132777_15 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000001189 95.0
DYD2_k127_3132777_16 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000349 100.0
DYD2_k127_3132777_17 DoxX K15977 - - 0.000000000005954 74.0
DYD2_k127_3132777_18 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.0000000001653 69.0
DYD2_k127_3132777_19 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins K03217 - - 0.000002845 57.0
DYD2_k127_3132777_2 Threonine synthase N terminus K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 534.0
DYD2_k127_3132777_20 domain, Protein - - - 0.00009892 51.0
DYD2_k127_3132777_21 Protein of unknown function (DUF3592) - - - 0.0002548 53.0
DYD2_k127_3132777_22 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.0002898 49.0
DYD2_k127_3132777_23 domain, Protein K09798 - - 0.0007335 51.0
DYD2_k127_3132777_3 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 463.0
DYD2_k127_3132777_4 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 400.0
DYD2_k127_3132777_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 342.0
DYD2_k127_3132777_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000001477 248.0
DYD2_k127_3132777_7 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000005718 241.0
DYD2_k127_3132777_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000001402 205.0
DYD2_k127_3132777_9 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000122 188.0
DYD2_k127_3161243_0 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000004178 136.0
DYD2_k127_3183980_0 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 302.0
DYD2_k127_3183980_1 Short-chain dehydrogenase reductase sdr K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.000000000000000000000000000000000000000000002934 173.0
DYD2_k127_3183980_2 - - - - 0.000000006864 63.0
DYD2_k127_3183980_3 methyltransferase - - - 0.0000007305 54.0
DYD2_k127_3183980_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00002395 55.0
DYD2_k127_3209019_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 5.901e-263 825.0
DYD2_k127_3209019_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.052e-202 652.0
DYD2_k127_3209019_10 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000003872 177.0
DYD2_k127_3209019_11 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000002577 166.0
DYD2_k127_3209019_12 RmuC family K09760 - - 0.0000000000000000000000000000000000000171 156.0
DYD2_k127_3209019_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000001282 93.0
DYD2_k127_3209019_15 Membrane - - - 0.000000000000000001304 100.0
DYD2_k127_3209019_16 GIY-YIG catalytic domain - - - 0.00000000000001215 78.0
DYD2_k127_3209019_17 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000006507 81.0
DYD2_k127_3209019_18 Belongs to the peptidase S26 family - - - 0.0000000000002331 74.0
DYD2_k127_3209019_19 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000879 76.0
DYD2_k127_3209019_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 629.0
DYD2_k127_3209019_20 TIGRFAM Sporulation protein YteA - - - 0.00000000004396 68.0
DYD2_k127_3209019_21 Belongs to the UPF0235 family K09131 - - 0.0000000001598 64.0
DYD2_k127_3209019_22 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000006291 61.0
DYD2_k127_3209019_23 Protein conserved in bacteria - - - 0.000000003286 67.0
DYD2_k127_3209019_24 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000001102 55.0
DYD2_k127_3209019_25 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000001864 56.0
DYD2_k127_3209019_26 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00008505 48.0
DYD2_k127_3209019_3 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 527.0
DYD2_k127_3209019_4 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 473.0
DYD2_k127_3209019_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 421.0
DYD2_k127_3209019_6 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 302.0
DYD2_k127_3209019_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000005505 221.0
DYD2_k127_3209019_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000003067 215.0
DYD2_k127_3209019_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000001283 196.0
DYD2_k127_3323539_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.736e-295 919.0
DYD2_k127_3323539_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000009565 199.0
DYD2_k127_3323539_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000168 177.0
DYD2_k127_3323539_3 Peptidase family M50 - - - 0.00000000000000000000000000000000000007769 151.0
DYD2_k127_346705_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 506.0
DYD2_k127_346705_1 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 418.0
DYD2_k127_346705_10 Metalloenzyme superfamily - - - 0.00000000000000001626 94.0
DYD2_k127_346705_11 Tetratricopeptide repeat - - - 0.000003517 60.0
DYD2_k127_346705_12 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000007993 53.0
DYD2_k127_346705_13 PhoQ Sensor - - - 0.0006342 53.0
DYD2_k127_346705_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 382.0
DYD2_k127_346705_3 COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000001261 235.0
DYD2_k127_346705_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000001769 206.0
DYD2_k127_346705_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000006033 178.0
DYD2_k127_346705_6 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000002874 166.0
DYD2_k127_346705_8 PFAM response regulator receiver - - - 0.0000000000000000000000009309 108.0
DYD2_k127_346705_9 STAS domain - - - 0.00000000000000000001152 96.0
DYD2_k127_3481588_0 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 339.0
DYD2_k127_3481588_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000303 267.0
DYD2_k127_3481588_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000001102 163.0
DYD2_k127_3481588_11 glycosyl transferase group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000001212 173.0
DYD2_k127_3481588_12 PFAM cyclase family protein K07130 - 3.5.1.9 0.000000000000000000000000000000000000003666 154.0
DYD2_k127_3481588_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000157 145.0
DYD2_k127_3481588_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000001853 134.0
DYD2_k127_3481588_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000005627 133.0
DYD2_k127_3481588_16 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000003657 128.0
DYD2_k127_3481588_17 Adenomatosis polyposis coli down-regulated 1 - - - 0.000000000000000000000000002527 119.0
DYD2_k127_3481588_18 PFAM ribosomal protein L17 K02879 - - 0.000000000000000000000002551 106.0
DYD2_k127_3481588_19 Glycosyltransferase like family 2 - - - 0.000000000000000000000004864 118.0
DYD2_k127_3481588_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000001611 232.0
DYD2_k127_3481588_20 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000001456 103.0
DYD2_k127_3481588_22 hydrolase, family 25 - - - 0.0000000000000000000005005 110.0
DYD2_k127_3481588_23 - - - - 0.000000000000007886 81.0
DYD2_k127_3481588_24 lytic transglycosylase activity K03194 - - 0.00000000000001679 87.0
DYD2_k127_3481588_25 Polysaccharide biosynthesis protein - - - 0.00000000116 71.0
DYD2_k127_3481588_26 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000001637 60.0
DYD2_k127_3481588_27 O-antigen ligase like membrane protein - - - 0.00003286 57.0
DYD2_k127_3481588_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000005925 228.0
DYD2_k127_3481588_4 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000008569 232.0
DYD2_k127_3481588_5 G8 - - - 0.00000000000000000000000000000000000000000000000000000000000001056 245.0
DYD2_k127_3481588_6 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000000000000000000004065 217.0
DYD2_k127_3481588_7 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000001831 196.0
DYD2_k127_3481588_8 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000006302 188.0
DYD2_k127_3481588_9 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000001274 190.0
DYD2_k127_3493004_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000002918 213.0
DYD2_k127_3493004_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000008475 149.0
DYD2_k127_3493004_2 Psort location Cytoplasmic, score K08234 - - 0.0000000000000001358 83.0
DYD2_k127_3520791_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000009175 207.0
DYD2_k127_3520791_1 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000002952 156.0
DYD2_k127_3520791_2 Domain of unknown function DUF11 - - - 0.00000003221 66.0
DYD2_k127_3571834_0 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 484.0
DYD2_k127_3571834_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 419.0
DYD2_k127_3571834_2 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 325.0
DYD2_k127_3571834_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002021 280.0
DYD2_k127_3571834_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000114 168.0
DYD2_k127_3571834_5 phosphoribosyl-ATP pyrophosphohydrolase - - - 0.00000000000000000004038 101.0
DYD2_k127_3571834_6 Chaperone of endosialidase - - - 0.000000000000000005442 100.0
DYD2_k127_3735418_0 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000001371 235.0
DYD2_k127_3735418_1 N-terminal domain of ribose phosphate pyrophosphokinase - - - 0.00000000000000000000000000000000000000000000000000000000000001997 228.0
DYD2_k127_3735418_10 - - - - 0.00000000004284 64.0
DYD2_k127_3735418_11 Unextendable partial coding region - - - 0.0000000005772 64.0
DYD2_k127_3735418_12 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000002223 60.0
DYD2_k127_3735418_13 Protein of unknown function (DUF3137) - - - 0.00002717 56.0
DYD2_k127_3735418_14 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.0001373 49.0
DYD2_k127_3735418_15 COG NOG15344 non supervised orthologous group - - - 0.0005102 43.0
DYD2_k127_3735418_16 Hydrolase K21471 - - 0.0008169 49.0
DYD2_k127_3735418_17 - - - - 0.0008741 42.0
DYD2_k127_3735418_2 COGs COG0503 Adenine guanine phosphoribosyltransferase and related PRPP-binding protein K00759 - 2.4.2.7 0.000000000000000000000000000000000000004074 160.0
DYD2_k127_3735418_3 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000004615 142.0
DYD2_k127_3735418_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000005538 124.0
DYD2_k127_3735418_5 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000002467 111.0
DYD2_k127_3735418_6 Transcriptional regulator, TrmB - - - 0.0000000000000000000000002068 115.0
DYD2_k127_3735418_7 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000004363 108.0
DYD2_k127_3735418_9 Belongs to the AAA ATPase family K08956 - - 0.000000000002767 74.0
DYD2_k127_3755133_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 577.0
DYD2_k127_3755133_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001509 238.0
DYD2_k127_3755133_2 Shikimate kinase K00891 - 2.7.1.71 0.000000000000000000000000000000000003136 145.0
DYD2_k127_376502_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 524.0
DYD2_k127_376502_1 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 389.0
DYD2_k127_376502_10 the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA K02341 - 2.7.7.7 0.000000000000000000000000289 117.0
DYD2_k127_376502_11 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000002017 102.0
DYD2_k127_376502_12 methylamine metabolic process K15977 - - 0.0000000003253 71.0
DYD2_k127_376502_13 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000644 61.0
DYD2_k127_376502_14 DUF218 domain - - - 0.00002493 50.0
DYD2_k127_376502_15 Transcriptional regulator - - - 0.0000276 54.0
DYD2_k127_376502_16 Peptidase M22 glycoprotease K01409,K14742 - 2.3.1.234 0.00003168 53.0
DYD2_k127_376502_17 YecM protein K09907 - - 0.00008728 52.0
DYD2_k127_376502_18 Peptidase family M23 - - - 0.00009486 53.0
DYD2_k127_376502_19 Tetratricopeptide repeats - - - 0.00009995 54.0
DYD2_k127_376502_2 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 301.0
DYD2_k127_376502_20 Peptidase_C39 like family - - - 0.0005135 50.0
DYD2_k127_376502_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000515 293.0
DYD2_k127_376502_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000004401 210.0
DYD2_k127_376502_5 Glycosyltransferase like family 2 K03606,K07011 - - 0.000000000000000000000000000000000000000000000000000000379 204.0
DYD2_k127_376502_6 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000004224 197.0
DYD2_k127_376502_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000001526 191.0
DYD2_k127_376502_8 cytoplasmic translational termination K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000001274 153.0
DYD2_k127_376502_9 Protein of unknown function (DUF4012) - - - 0.0000000000000000000000000000000000001985 161.0
DYD2_k127_3771285_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold K00650 - 2.3.1.43 0.000000000000000002768 91.0
DYD2_k127_3771285_1 - - - - 0.000000000000000004466 93.0
DYD2_k127_3903385_0 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00001151 55.0
DYD2_k127_3938430_0 Domain of unknown function (DUF3394) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
DYD2_k127_3938430_1 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006193 242.0
DYD2_k127_3950988_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000007115 102.0
DYD2_k127_4017329_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.403e-235 747.0
DYD2_k127_4017329_1 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
DYD2_k127_4017329_2 Phosphoglycerate mutase domain-containing protein. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 302.0
DYD2_k127_4017329_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 289.0
DYD2_k127_4017329_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000002321 87.0
DYD2_k127_4017329_5 PFAM ADP-ribosylglycohydrolase - - - 0.0000000001273 73.0
DYD2_k127_4017329_6 endocytosis K03068,K20050 - - 0.0000004846 59.0
DYD2_k127_4058876_0 Oligoendopeptidase f K01283,K08602 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 372.0
DYD2_k127_4058876_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000008073 256.0
DYD2_k127_4058876_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000005019 126.0
DYD2_k127_4058876_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000198 66.0
DYD2_k127_4065540_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.885e-249 791.0
DYD2_k127_4065540_1 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 442.0
DYD2_k127_4065540_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000001133 183.0
DYD2_k127_4065540_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000001328 181.0
DYD2_k127_4065540_12 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000001964 158.0
DYD2_k127_4065540_13 EamA-like transporter family - - - 0.00000000000000000000000000000002976 138.0
DYD2_k127_4065540_14 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000002993 127.0
DYD2_k127_4065540_15 NifU domain protein - - - 0.00000000000001304 80.0
DYD2_k127_4065540_16 - - - - 0.00000000000009899 80.0
DYD2_k127_4065540_18 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000301 79.0
DYD2_k127_4065540_19 Ham1 family - - - 0.000000000008915 74.0
DYD2_k127_4065540_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000879 290.0
DYD2_k127_4065540_20 cellulase activity K14194,K14201,K20276 GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743 - 0.000000007683 66.0
DYD2_k127_4065540_21 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.00000005166 65.0
DYD2_k127_4065540_22 PFAM Phosphoribulokinase Uridine kinase family K00876 - 2.7.1.48 0.000004646 59.0
DYD2_k127_4065540_23 PFAM ATP-binding region ATPase domain protein - - - 0.000006756 54.0
DYD2_k127_4065540_24 Belongs to the pyrimidine 5'-nucleotidase family K01081 - 3.1.3.5 0.00001382 57.0
DYD2_k127_4065540_25 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00008467 50.0
DYD2_k127_4065540_26 C-terminal domain of CHU protein family - - - 0.0004228 54.0
DYD2_k127_4065540_27 phosphoserine phosphatase K01079 - 3.1.3.3 0.0006263 50.0
DYD2_k127_4065540_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000008003 254.0
DYD2_k127_4065540_4 type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002064 251.0
DYD2_k127_4065540_5 UMP kinase activity K00947,K09903 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030151,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000154 230.0
DYD2_k127_4065540_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000001159 231.0
DYD2_k127_4065540_7 TIGRFAM RecB family nuclease - - - 0.000000000000000000000000000000000000000000000000000000000004611 227.0
DYD2_k127_4065540_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000007514 229.0
DYD2_k127_4065540_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000005531 198.0
DYD2_k127_4101246_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 345.0
DYD2_k127_4101246_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000117 261.0
DYD2_k127_4101246_2 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.00000000000000000000000006134 110.0
DYD2_k127_4101246_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000005102 105.0
DYD2_k127_4101246_4 - - - - 0.0000000007095 70.0
DYD2_k127_4246624_0 Peptidase family M23 K21471 - - 0.0000000000000000000000005379 119.0
DYD2_k127_4255133_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000005629 174.0
DYD2_k127_4255133_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000002741 164.0
DYD2_k127_4282634_0 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 462.0
DYD2_k127_4282634_1 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006458 259.0
DYD2_k127_4282634_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004356 268.0
DYD2_k127_4282634_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000001929 246.0
DYD2_k127_4282634_4 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000007038 93.0
DYD2_k127_4282634_5 - - - - 0.0000009294 58.0
DYD2_k127_4282634_6 - K00960 - 2.7.7.6 0.00001146 58.0
DYD2_k127_4337040_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 328.0
DYD2_k127_4337040_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 294.0
DYD2_k127_4337040_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000003843 129.0
DYD2_k127_4337040_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000004457 93.0
DYD2_k127_4337040_4 Protein conserved in bacteria K06898,K09121,K09705 - 4.99.1.12 0.00000000000004535 74.0
DYD2_k127_4337040_5 ribosomal large subunit export from nucleus - - - 0.000000000002489 74.0
DYD2_k127_4515890_0 GTP-binding protein LepA C-terminus K03596 - - 1.597e-207 662.0
DYD2_k127_4515890_1 oligoendopeptidase F K08602 - - 1.312e-197 636.0
DYD2_k127_4515890_10 - - - - 0.000000000000000000000000004454 131.0
DYD2_k127_4515890_11 oxidoreductase activity - - - 0.00000000000000000000000005705 116.0
DYD2_k127_4515890_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000001589 111.0
DYD2_k127_4515890_13 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000001779 94.0
DYD2_k127_4515890_14 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000247 85.0
DYD2_k127_4515890_15 acetyltransferase K18816 - 2.3.1.82 0.000000000000004661 80.0
DYD2_k127_4515890_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 403.0
DYD2_k127_4515890_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
DYD2_k127_4515890_4 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 349.0
DYD2_k127_4515890_5 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008086 265.0
DYD2_k127_4515890_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000005971 256.0
DYD2_k127_4515890_7 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate K15024 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000008482 195.0
DYD2_k127_4515890_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000001712 137.0
DYD2_k127_4515890_9 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000000000128 120.0
DYD2_k127_4523712_0 alginic acid biosynthetic process K20276 - - 0.000000000000000009931 99.0
DYD2_k127_4601878_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 344.0
DYD2_k127_4819155_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 445.0
DYD2_k127_4819155_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000005363 215.0
DYD2_k127_4819155_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000002286 177.0
DYD2_k127_4819155_3 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000009994 174.0
DYD2_k127_4819155_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000002394 75.0
DYD2_k127_4844068_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.885e-260 826.0
DYD2_k127_4844068_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 615.0
DYD2_k127_4844068_10 ATP-binding protein K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000116 108.0
DYD2_k127_4844068_11 Diacylglycerol kinase catalytic domain - - - 0.0000000000000005155 91.0
DYD2_k127_4844068_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000005338 69.0
DYD2_k127_4844068_13 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000005311 56.0
DYD2_k127_4844068_14 HNH endonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00001458 57.0
DYD2_k127_4844068_2 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 372.0
DYD2_k127_4844068_3 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 344.0
DYD2_k127_4844068_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 304.0
DYD2_k127_4844068_5 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000006464 248.0
DYD2_k127_4844068_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000002202 197.0
DYD2_k127_4844068_7 Zn-dependent hydrolases of the - - - 0.0000000000000000000000000000000002333 140.0
DYD2_k127_4844068_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000003684 120.0
DYD2_k127_4844068_9 - - - - 0.000000000000000000000000005795 113.0
DYD2_k127_496482_0 - - - - 0.0000000000002771 78.0
DYD2_k127_496482_1 nuclear chromosome segregation - - - 0.00003564 57.0
DYD2_k127_496482_2 Terminase-like family - - - 0.000127 54.0
DYD2_k127_5079786_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 545.0
DYD2_k127_5079786_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 414.0
DYD2_k127_5079786_10 Glycosyltransferase like family K07011 - - 0.0000000000000000000000000000000000000000000000418 184.0
DYD2_k127_5079786_11 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000001287 181.0
DYD2_k127_5079786_12 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000002527 136.0
DYD2_k127_5079786_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000003402 106.0
DYD2_k127_5079786_14 NUDIX domain - - - 0.0000000000000000000003276 106.0
DYD2_k127_5079786_15 RmlD substrate binding domain - - - 0.0000000000000000000007205 106.0
DYD2_k127_5079786_16 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000001884 98.0
DYD2_k127_5079786_17 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000000000006621 89.0
DYD2_k127_5079786_18 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.000000000000118 80.0
DYD2_k127_5079786_19 PFAM methyltransferase - - - 0.000000000001534 76.0
DYD2_k127_5079786_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 386.0
DYD2_k127_5079786_20 Sugar-specific transcriptional regulator TrmB - - - 0.00008456 46.0
DYD2_k127_5079786_21 negative regulation of transcription, DNA-templated - - - 0.0002383 48.0
DYD2_k127_5079786_22 COG1437 Adenylate cyclase, class 2 (thermophilic) K05873 - 4.6.1.1 0.0005731 50.0
DYD2_k127_5079786_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 368.0
DYD2_k127_5079786_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000001676 273.0
DYD2_k127_5079786_5 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000003153 259.0
DYD2_k127_5079786_6 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000603 246.0
DYD2_k127_5079786_7 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000006232 232.0
DYD2_k127_5079786_8 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000001121 196.0
DYD2_k127_5079786_9 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000004888 200.0
DYD2_k127_5089280_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 501.0
DYD2_k127_5089280_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 404.0
DYD2_k127_5089280_2 Thioredoxin - - - 0.00000000000000000000000000001717 129.0
DYD2_k127_5089280_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold K00650 - 2.3.1.43 0.00000000000000000000000000003693 136.0
DYD2_k127_5089280_4 Periplasmic component of the Tol biopolymer transport system - - - 0.00003865 56.0
DYD2_k127_5089280_5 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0004465 53.0
DYD2_k127_5099573_0 GTP-binding protein TypA K06207 - - 1.231e-200 642.0
DYD2_k127_5099573_1 Guanylate kinase homologues. K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000003442 123.0
DYD2_k127_5099573_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000008626 102.0
DYD2_k127_5099573_3 - - - - 0.000001619 54.0
DYD2_k127_5099573_4 Protein of unknown function (DUF1059) - - - 0.000005563 50.0
DYD2_k127_5099573_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.000007255 59.0
DYD2_k127_5119244_0 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000005998 235.0
DYD2_k127_5119244_1 domain, Protein - - - 0.000000000000000000000000000000000004857 146.0
DYD2_k127_5119244_2 phage shock protein C K03973 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944 - 0.000004299 53.0
DYD2_k127_5130513_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000006186 96.0
DYD2_k127_513548_0 YadA-like membrane anchor domain K12342 - - 0.000000000000008103 89.0
DYD2_k127_5161495_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000831 280.0
DYD2_k127_5161495_1 Lysyl oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004962 269.0
DYD2_k127_5161495_2 Histidine kinase- DNA gyrase B - - - 0.000000000003251 68.0
DYD2_k127_5163908_0 Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000001535 183.0
DYD2_k127_5163908_1 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000551 125.0
DYD2_k127_5163908_2 Ferredoxin - - - 0.000000000000001298 80.0
DYD2_k127_5163908_3 EamA-like transporter family - - - 0.00000001394 66.0
DYD2_k127_5163908_4 Sugar-specific transcriptional regulator TrmB - - - 0.000001546 59.0
DYD2_k127_5361998_0 YadA-like membrane anchor domain K12342 - - 0.0003933 53.0
DYD2_k127_5542336_0 PFAM VanW family protein - - - 0.0000000000000000000000000000000000000000000000000000002873 216.0
DYD2_k127_5542336_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000001073 90.0
DYD2_k127_558821_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 465.0
DYD2_k127_558821_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000006367 245.0
DYD2_k127_558821_2 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000004322 231.0
DYD2_k127_558821_3 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000008353 216.0
DYD2_k127_558821_4 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000004262 99.0
DYD2_k127_558821_5 UPF0056 membrane protein K05595 - - 0.0000001519 55.0
DYD2_k127_558821_6 PhoQ Sensor - - - 0.000000575 62.0
DYD2_k127_558821_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00002185 57.0
DYD2_k127_558821_8 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.00009303 49.0
DYD2_k127_5633922_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 598.0
DYD2_k127_5633922_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 312.0
DYD2_k127_5633922_2 Multicopper oxidase K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001209 261.0
DYD2_k127_5633922_3 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000001829 225.0
DYD2_k127_5633922_4 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.000000000000000000000000000000000000000000000000000001479 207.0
DYD2_k127_5633922_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000006951 155.0
DYD2_k127_5633922_6 CAAX protease self-immunity - - - 0.00000000000000000000000000000000002471 145.0
DYD2_k127_5633922_7 ASCH - - - 0.000001052 57.0
DYD2_k127_5633922_8 WD40-like Beta Propeller Repeat K03641 - - 0.00000145 60.0
DYD2_k127_5672562_0 malic enzyme K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000139 258.0
DYD2_k127_5672562_1 EVE domain - - - 0.0000000000000000000000000000000000000000000000000007661 188.0
DYD2_k127_5672562_2 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000159 102.0
DYD2_k127_5695990_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 309.0
DYD2_k127_5695990_1 adenosine deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000001006 248.0
DYD2_k127_5695990_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000003899 201.0
DYD2_k127_5695990_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356,K03503 - 3.4.21.88 0.000000000000000000000000000000000000000000003523 177.0
DYD2_k127_5695990_4 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000353 132.0
DYD2_k127_5695990_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031974,GO:0032543,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140053,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000001262 112.0
DYD2_k127_5705306_0 PFAM TrkA-N domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 376.0
DYD2_k127_5705306_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 314.0
DYD2_k127_5705306_10 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 0.00000000000000000000000000000000000001878 155.0
DYD2_k127_5705306_11 Reductase C-terminal K00529 - 1.18.1.3 0.0000000000000000000000000000000000004179 154.0
DYD2_k127_5705306_12 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000003066 145.0
DYD2_k127_5705306_13 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000333 146.0
DYD2_k127_5705306_14 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000003655 156.0
DYD2_k127_5705306_15 Mg2 transporter-C family protein K07507 - - 0.000000000000000000000000000000006173 133.0
DYD2_k127_5705306_16 Peptidase family M28 - - - 0.000000000000000000000000000000007169 134.0
DYD2_k127_5705306_17 Glycosyl transferase family 2 - - - 0.0000000000000000000000000001203 134.0
DYD2_k127_5705306_18 - - - - 0.00000000000000000000002036 109.0
DYD2_k127_5705306_19 COG NOG14552 non supervised orthologous group - - - 0.0000000000000000001547 91.0
DYD2_k127_5705306_2 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 310.0
DYD2_k127_5705306_20 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000004098 96.0
DYD2_k127_5705306_22 Helix-turn-helix domain K07729 - - 0.00000000000000004335 82.0
DYD2_k127_5705306_23 PFAM histidine kinase, HAMP region domain protein K03406,K03776,K05874,K05875 - - 0.0000000000000001326 95.0
DYD2_k127_5705306_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000003751 92.0
DYD2_k127_5705306_25 Cold shock protein domain K03704 - - 0.0000000000000005648 79.0
DYD2_k127_5705306_26 - - - - 0.000000000000002608 75.0
DYD2_k127_5705306_27 - - - - 0.00000000000001724 74.0
DYD2_k127_5705306_28 - - - - 0.00000000000002515 76.0
DYD2_k127_5705306_29 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000001914 81.0
DYD2_k127_5705306_3 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
DYD2_k127_5705306_30 - - - - 0.000000000003181 67.0
DYD2_k127_5705306_31 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K05337 - - 0.00000000006319 66.0
DYD2_k127_5705306_32 - - - - 0.0000000001368 63.0
DYD2_k127_5705306_33 copper amine oxidase - - - 0.0000000001389 73.0
DYD2_k127_5705306_34 cell redox homeostasis K12057 - - 0.0000000006626 70.0
DYD2_k127_5705306_35 - - - - 0.0000004734 52.0
DYD2_k127_5705306_36 - - - - 0.000004436 49.0
DYD2_k127_5705306_37 Peptidoglycan-binding lysin domain - - - 0.000004589 57.0
DYD2_k127_5705306_38 helix_turn_helix, arabinose operon control protein - - - 0.00002103 55.0
DYD2_k127_5705306_4 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000003504 237.0
DYD2_k127_5705306_5 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000003716 220.0
DYD2_k127_5705306_6 abc transporter atp-binding protein K06158 - - 0.000000000000000000000000000000000000000000000000000000009564 218.0
DYD2_k127_5705306_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000353 194.0
DYD2_k127_5705306_8 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002801 197.0
DYD2_k127_5705306_9 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000009832 168.0
DYD2_k127_5751388_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 492.0
DYD2_k127_5762012_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1069.0
DYD2_k127_5762012_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 433.0
DYD2_k127_5762012_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004611 290.0
DYD2_k127_5762012_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000002068 187.0
DYD2_k127_5762012_4 Thioredoxin - - - 0.00000000000000000000000000000000000004216 152.0
DYD2_k127_5762012_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000004026 126.0
DYD2_k127_5762012_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000002851 108.0
DYD2_k127_5762012_7 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000002734 64.0
DYD2_k127_5762012_8 Phosphopantetheine attachment site - - - 0.000000004925 68.0
DYD2_k127_5931501_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 348.0
DYD2_k127_5931501_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 299.0
DYD2_k127_5931501_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000001165 64.0
DYD2_k127_5952377_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.763e-217 681.0
DYD2_k127_5952377_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 7.367e-202 640.0
DYD2_k127_5952377_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000001109 228.0
DYD2_k127_5952377_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000003858 168.0
DYD2_k127_5952377_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000005268 71.0
DYD2_k127_5952377_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000001374 62.0
DYD2_k127_5952377_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000014 60.0
DYD2_k127_5961227_0 PFAM DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 411.0
DYD2_k127_5961227_1 - - - - 0.00000000000000000000000000000000000000004742 162.0
DYD2_k127_5961227_2 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000518 147.0
DYD2_k127_5961227_3 - K08641 - 3.4.13.22 0.0000000000000000000000000000009714 134.0
DYD2_k127_5961227_4 - - - - 0.0000000000000000000000004548 113.0
DYD2_k127_5961227_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0005907 48.0
DYD2_k127_598289_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 543.0
DYD2_k127_598289_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 397.0
DYD2_k127_598289_10 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000001156 132.0
DYD2_k127_598289_11 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000001705 116.0
DYD2_k127_598289_12 RNA recognition motif - - - 0.0000000000000000000004741 98.0
DYD2_k127_598289_13 Belongs to the UPF0102 family K07460 - - 0.0000000000000000003095 93.0
DYD2_k127_598289_14 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000002184 91.0
DYD2_k127_598289_15 - - - - 0.000000000000007681 87.0
DYD2_k127_598289_16 phenylacetate-CoA ligase activity - - - 0.000000000000009863 81.0
DYD2_k127_598289_17 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000001377 78.0
DYD2_k127_598289_18 nucleotidyltransferase activity - - - 0.000000000007528 78.0
DYD2_k127_598289_19 TM2 domain - - - 0.0000004544 55.0
DYD2_k127_598289_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 352.0
DYD2_k127_598289_20 lipid kinase, YegS Rv2252 BmrU family - - - 0.000001127 59.0
DYD2_k127_598289_21 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000001829 59.0
DYD2_k127_598289_22 domain protein - - - 0.000002278 57.0
DYD2_k127_598289_24 protein secretion by the type IV secretion system K03201 - - 0.00002701 58.0
DYD2_k127_598289_26 domain protein - - - 0.0003162 56.0
DYD2_k127_598289_3 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 329.0
DYD2_k127_598289_4 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
DYD2_k127_598289_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000002157 200.0
DYD2_k127_598289_6 guanidinoacetate N-methyltransferase activity K00542 GO:0000003,GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006575,GO:0006600,GO:0006601,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006936,GO:0007275,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0008168,GO:0008652,GO:0008757,GO:0009058,GO:0009116,GO:0009119,GO:0009653,GO:0009790,GO:0009887,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0019752,GO:0019953,GO:0022414,GO:0030731,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0034641,GO:0040008,GO:0040014,GO:0042278,GO:0042398,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0046128,GO:0046394,GO:0046483,GO:0046498,GO:0046500,GO:0046983,GO:0048232,GO:0048513,GO:0048568,GO:0048609,GO:0048638,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0051186,GO:0051239,GO:0051704,GO:0055086,GO:0065007,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1990402 2.1.1.2 0.000000000000000000000000000000000000000000000005745 181.0
DYD2_k127_598289_7 response regulator receiver - - - 0.00000000000000000000000000000000004725 153.0
DYD2_k127_598289_8 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000000000000005909 136.0
DYD2_k127_598289_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000003502 127.0
DYD2_k127_5998205_0 orotidine-5'-phosphate decarboxylase activity K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000001233 189.0
DYD2_k127_5998205_1 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.00000000000000000000000000001808 127.0
DYD2_k127_6004914_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 400.0
DYD2_k127_6004914_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 347.0
DYD2_k127_6004914_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009362 279.0
DYD2_k127_6004914_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000009603 209.0
DYD2_k127_6004914_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000001882 131.0
DYD2_k127_6004914_5 Trypsin-like peptidase domain K04771,K08669 - 3.4.21.107,3.4.21.108 0.000000000744 70.0
DYD2_k127_6017533_0 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 384.0
DYD2_k127_6017533_1 - - - - 0.000000000000166 79.0
DYD2_k127_605392_0 PQQ-like domain - - - 0.00000000000004415 85.0
DYD2_k127_605392_1 Glycosyltransferase Family 4 - - - 0.000000003732 62.0
DYD2_k127_605392_2 Capsular polysaccharide biosynthesis protein - - - 0.00000001549 64.0
DYD2_k127_605392_3 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000006796 55.0
DYD2_k127_605392_5 O-Antigen ligase - - - 0.0001879 54.0
DYD2_k127_6065261_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
DYD2_k127_6065261_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000001501 118.0
DYD2_k127_6070204_0 D5 N terminal like - - - 0.00000000000000000000000000000000006522 151.0
DYD2_k127_6070204_1 - - - - 0.000000000000000000005188 104.0
DYD2_k127_6070204_3 Bifunctional DNA primase/polymerase, N-terminal - - - 0.00000000000000005361 94.0
DYD2_k127_6070204_5 - - - - 0.000000007192 71.0
DYD2_k127_6070204_6 cellulase activity - - - 0.0000004644 65.0
DYD2_k127_6070204_8 sporulation resulting in formation of a cellular spore - - - 0.0007683 54.0
DYD2_k127_6209090_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 574.0
DYD2_k127_6209090_1 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 460.0
DYD2_k127_6209090_10 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001221 248.0
DYD2_k127_6209090_11 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000006821 242.0
DYD2_k127_6209090_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000009887 233.0
DYD2_k127_6209090_13 TIGRFAM Nicotinamide mononucleotide transporter PnuC K03811 - - 0.000000000000000000000000000000000000000000000000000000000003652 216.0
DYD2_k127_6209090_14 - - - - 0.00000000000000000000000000005552 128.0
DYD2_k127_6209090_15 Psort location Cytoplasmic, score K07043 - - 0.00000000000000000000000002706 117.0
DYD2_k127_6209090_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000001501 78.0
DYD2_k127_6209090_17 - - - - 0.0000000000002257 82.0
DYD2_k127_6209090_18 DUF218 domain - - - 0.00000000002748 72.0
DYD2_k127_6209090_2 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 445.0
DYD2_k127_6209090_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 363.0
DYD2_k127_6209090_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 366.0
DYD2_k127_6209090_5 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 355.0
DYD2_k127_6209090_6 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 367.0
DYD2_k127_6209090_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001946 284.0
DYD2_k127_6209090_8 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002321 291.0
DYD2_k127_6209090_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007467 271.0
DYD2_k127_6232577_0 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 539.0
DYD2_k127_6232577_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 429.0
DYD2_k127_6232577_10 PFAM O-antigen polymerase - - - 0.000000000000002581 89.0
DYD2_k127_6232577_11 Stage II sporulation D domain protein K06381 - - 0.0000000000004625 83.0
DYD2_k127_6232577_13 VKc - - - 0.0000001956 59.0
DYD2_k127_6232577_14 Bacterial PH domain K08981 - - 0.000002366 57.0
DYD2_k127_6232577_15 Glycosyl hydrolases family 25 K07273 - - 0.000004333 59.0
DYD2_k127_6232577_16 - - - - 0.0000386 51.0
DYD2_k127_6232577_17 - - - - 0.00007549 56.0
DYD2_k127_6232577_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004392 277.0
DYD2_k127_6232577_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001236 266.0
DYD2_k127_6232577_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000001929 152.0
DYD2_k127_6232577_5 HNH endonuclease - - - 0.00000000000000000000000000000000029 138.0
DYD2_k127_6232577_6 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.0000000000000000000000000002253 128.0
DYD2_k127_6232577_7 Polysaccharide biosynthesis protein - - - 0.00000000000000000002212 106.0
DYD2_k127_6232577_8 -O-antigen - - - 0.00000000000000001913 95.0
DYD2_k127_6232577_9 ABC transporter K02027 - - 0.000000000000001038 91.0
DYD2_k127_6249882_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008039 239.0
DYD2_k127_6249882_1 Shikimate kinase K00891 - 2.7.1.71 0.0000000000000000000000000000000009151 138.0
DYD2_k127_6249882_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.000001342 55.0
DYD2_k127_6352535_0 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000000004496 139.0
DYD2_k127_638912_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000007653 196.0
DYD2_k127_638912_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold K00650 - 2.3.1.43 0.0001036 50.0
DYD2_k127_6420377_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 527.0
DYD2_k127_6420377_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 325.0
DYD2_k127_6420377_2 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000001606 164.0
DYD2_k127_6420377_3 Bacterial DNA-binding protein K03530 - - 0.000000000000000000000008034 104.0
DYD2_k127_6420377_4 Sulfurtransferase - - - 0.0000007266 57.0
DYD2_k127_6494268_0 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000004247 128.0
DYD2_k127_6494268_1 Bacterial sugar transferase - - - 0.0000000000000000000000000000006257 123.0
DYD2_k127_6494268_2 Methyltransferase - - - 0.000000000000003391 85.0
DYD2_k127_6500021_0 TIGRFAM SUF system FeS cluster assembly, SufB K07033,K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 601.0
DYD2_k127_6500021_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 443.0
DYD2_k127_6500021_10 - - - - 0.00000596 55.0
DYD2_k127_6500021_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
DYD2_k127_6500021_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
DYD2_k127_6500021_4 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000001509 136.0
DYD2_k127_6500021_5 TIGRFAM FeS assembly protein SufD K09015 - - 0.0000000000000000000000000001604 125.0
DYD2_k127_6500021_6 lytic transglycosylase activity K03194 - - 0.000000000000000000000001058 117.0
DYD2_k127_6500021_7 COG1512 Beta-propeller domains of methanol dehydrogenase type - - - 0.000000000000000001388 101.0
DYD2_k127_6500021_8 metal-sulfur cluster biosynthetic - - - 0.000000000000000009071 86.0
DYD2_k127_6500021_9 Transcriptional regulator K13643 - - 0.000000000007603 71.0
DYD2_k127_6585615_0 Nodulation protein S (NodS) - - - 0.0005739 51.0
DYD2_k127_6705389_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000195 153.0
DYD2_k127_6705389_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000001109 137.0
DYD2_k127_714376_0 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000003028 165.0
DYD2_k127_714376_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000001244 132.0
DYD2_k127_756464_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000004888 228.0
DYD2_k127_809948_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 3.774e-266 857.0
DYD2_k127_809948_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 619.0
DYD2_k127_809948_10 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000003766 137.0
DYD2_k127_809948_11 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000007541 129.0
DYD2_k127_809948_12 Metallo-beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000782 121.0
DYD2_k127_809948_13 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.000000000000000000000002836 106.0
DYD2_k127_809948_14 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000006865 112.0
DYD2_k127_809948_15 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000414 58.0
DYD2_k127_809948_16 Cupredoxin-like domain - - - 0.000512 51.0
DYD2_k127_809948_2 Transketolase, pyrimidine binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 367.0
DYD2_k127_809948_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 325.0
DYD2_k127_809948_4 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 320.0
DYD2_k127_809948_5 1-deoxy-D-xylulose-5-phosphate synthase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 296.0
DYD2_k127_809948_6 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000558 304.0
DYD2_k127_809948_7 phosphotransferase activity, for other substituted phosphate groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001643 292.0
DYD2_k127_809948_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000002144 194.0
DYD2_k127_809948_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000005773 145.0
DYD2_k127_849990_0 ferric reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002203 267.0
DYD2_k127_849990_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000865 119.0
DYD2_k127_849990_2 Excinuclease ABC, C subunit K07461 - - 0.000000000000000000000000003361 114.0
DYD2_k127_859_0 Vitamin k epoxide reductase - - - 0.0000000000000000002668 93.0
DYD2_k127_859_2 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.0001189 51.0
DYD2_k127_862801_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 295.0
DYD2_k127_862801_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006168 258.0
DYD2_k127_862801_2 PFAM sigma-70 region 2 domain protein, Sigma-70 region 4 type 2 K03088 - - 0.00000000000000006226 87.0
DYD2_k127_862801_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000307 69.0
DYD2_k127_862801_4 thiolester hydrolase activity K06889 - - 0.0000000005705 68.0
DYD2_k127_862801_5 Tfp pilus assembly protein FimV - - - 0.0002234 53.0
DYD2_k127_874303_0 malic enzyme K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000006122 255.0
DYD2_k127_874303_1 EVE domain - - - 0.000000000000000000000000000000000000000000000000004359 185.0
DYD2_k127_906573_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000127 179.0
DYD2_k127_906573_2 S-layer homology domain - - - 0.00001555 59.0
DYD2_k127_925314_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 574.0
DYD2_k127_925314_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 391.0
DYD2_k127_925314_10 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000002366 230.0
DYD2_k127_925314_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000004166 221.0
DYD2_k127_925314_12 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000002252 202.0
DYD2_k127_925314_13 Psort location Cytoplasmic, score 9.98 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000645 211.0
DYD2_k127_925314_14 endonuclease III K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000001081 187.0
DYD2_k127_925314_15 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000003118 184.0
DYD2_k127_925314_16 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000000000777 190.0
DYD2_k127_925314_17 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000000000006837 173.0
DYD2_k127_925314_18 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000008658 168.0
DYD2_k127_925314_19 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000004912 164.0
DYD2_k127_925314_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 390.0
DYD2_k127_925314_20 Hydrolase, NUDIX family K01515 - 3.6.1.13 0.00000000000000000000000000000002538 132.0
DYD2_k127_925314_21 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000004175 116.0
DYD2_k127_925314_22 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000239 105.0
DYD2_k127_925314_23 Zincin-like metallopeptidase - - - 0.0000000000000000000008971 99.0
DYD2_k127_925314_24 protein conserved in bacteria K01768 - 4.6.1.1 0.000000000000000000004788 100.0
DYD2_k127_925314_25 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000568 87.0
DYD2_k127_925314_26 Glyoxalase-like domain - - - 0.000000000008435 70.0
DYD2_k127_925314_27 Calcineurin-like phosphoesterase - - - 0.00000000002073 77.0
DYD2_k127_925314_28 Translin. Source PGD - - - 0.00000001514 63.0
DYD2_k127_925314_29 PFAM phosphoesterase, RecJ domain protein - - - 0.00000119 60.0
DYD2_k127_925314_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 357.0
DYD2_k127_925314_30 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00006544 56.0
DYD2_k127_925314_31 - K06147 - - 0.0001791 53.0
DYD2_k127_925314_33 Membrane-flanked domain-containing protein - - - 0.0005504 49.0
DYD2_k127_925314_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 325.0
DYD2_k127_925314_5 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928,K15792 - 6.3.2.10,6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 320.0
DYD2_k127_925314_6 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007918 287.0
DYD2_k127_925314_7 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000006641 250.0
DYD2_k127_925314_8 cell division ATP-binding protein FtsE K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000001195 256.0
DYD2_k127_925314_9 COG1253 Hemolysins and related proteins containing CBS domains - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000001665 234.0