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Overview

ID MAG01000
Name EH1_bin.2
Sample SMP0028
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family JACTUA01
Genus JAJRCM01
Species
Assembly information
Completeness (%) 77.84
Contamination (%) 0.26
GC content (%) 52.0
N50 (bp) 16,923
Genome size (bp) 1,127,192

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1254

Gene name Description KEGG GOs EC E-value Score Sequence
EH1_k127_1124175_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 420.0
EH1_k127_1124175_1 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000000000000000000000000000002451 223.0
EH1_k127_1124175_2 acetyltransferase K03824 - - 0.000000000000000001024 91.0
EH1_k127_1124175_3 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000001825 77.0
EH1_k127_1124175_4 Lon protease (S16) C-terminal proteolytic domain - - - 0.000003529 51.0
EH1_k127_1204711_0 PFAM ribonuclease II K01147 - 3.1.13.1 2.066e-203 644.0
EH1_k127_1204711_1 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003024 246.0
EH1_k127_1204711_2 PFAM Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000001514 200.0
EH1_k127_1255360_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1328.0
EH1_k127_1255360_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.105e-310 961.0
EH1_k127_1255360_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000001375 173.0
EH1_k127_1255360_11 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000004034 171.0
EH1_k127_1255360_12 ATP synthase subunit K K02124 - - 0.0000000000000000000000000000000000000000002896 163.0
EH1_k127_1255360_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000003097 163.0
EH1_k127_1255360_14 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000003713 122.0
EH1_k127_1255360_15 ThiS family K03636 - - 0.0000000000000000000000000005583 115.0
EH1_k127_1255360_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000002128 103.0
EH1_k127_1255360_17 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000007737 96.0
EH1_k127_1255360_18 Ferredoxin K05337 - - 0.0000000000000000009461 89.0
EH1_k127_1255360_19 PFAM ABC-2 type transporter K01992 - - 0.000000000000000002744 89.0
EH1_k127_1255360_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 5.465e-248 777.0
EH1_k127_1255360_21 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000003634 82.0
EH1_k127_1255360_22 - - - - 0.000000000000003758 82.0
EH1_k127_1255360_23 PspC domain K03973 - - 0.000002238 51.0
EH1_k127_1255360_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.555e-213 668.0
EH1_k127_1255360_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 602.0
EH1_k127_1255360_5 V-type ATP synthase, subunit I K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 349.0
EH1_k127_1255360_6 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 305.0
EH1_k127_1255360_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000003005 188.0
EH1_k127_1255360_8 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000001178 185.0
EH1_k127_1255360_9 AMP binding - - - 0.000000000000000000000000000000000000000000001146 176.0
EH1_k127_1286721_0 PFAM ABC transporter K00400 - - 1.021e-282 875.0
EH1_k127_1286721_1 COG0464 ATPases of the AAA class K13525 - - 1.216e-271 857.0
EH1_k127_1286721_10 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 454.0
EH1_k127_1286721_11 methanogenesis marker protein 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 437.0
EH1_k127_1286721_12 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 406.0
EH1_k127_1286721_13 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 395.0
EH1_k127_1286721_14 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 386.0
EH1_k127_1286721_15 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 381.0
EH1_k127_1286721_16 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 374.0
EH1_k127_1286721_17 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 362.0
EH1_k127_1286721_18 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 353.0
EH1_k127_1286721_19 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 347.0
EH1_k127_1286721_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 1.394e-216 677.0
EH1_k127_1286721_20 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
EH1_k127_1286721_21 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
EH1_k127_1286721_22 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 295.0
EH1_k127_1286721_23 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
EH1_k127_1286721_24 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000001243 246.0
EH1_k127_1286721_25 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001798 232.0
EH1_k127_1286721_26 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.000000000000000000000000000000000000000000000000000000000005563 213.0
EH1_k127_1286721_27 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000003346 188.0
EH1_k127_1286721_28 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.000000000000000000000000000000000000000000000000000652 188.0
EH1_k127_1286721_29 PFAM Glycosyl transferase, group 1 K06338,K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000001004 188.0
EH1_k127_1286721_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 3.171e-208 655.0
EH1_k127_1286721_30 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000002058 177.0
EH1_k127_1286721_31 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000001012 120.0
EH1_k127_1286721_32 HEAT repeat - - - 0.00000000000000000002284 98.0
EH1_k127_1286721_33 Histidine kinase-like ATPases - - - 0.000000004713 68.0
EH1_k127_1286721_4 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 6.554e-196 622.0
EH1_k127_1286721_5 Starch synthase catalytic domain - - - 1.544e-194 614.0
EH1_k127_1286721_6 TIGRFAM UbiD family - - - 5.247e-194 612.0
EH1_k127_1286721_7 Glycogen debranching enzyme N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 609.0
EH1_k127_1286721_8 Belongs to the UPF0288 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 552.0
EH1_k127_1286721_9 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 538.0
EH1_k127_1290046_0 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005785 273.0
EH1_k127_1290046_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002173 258.0
EH1_k127_1290046_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000006795 147.0
EH1_k127_1290046_3 - - - - 0.0000000000000000000000000001218 116.0
EH1_k127_1369883_0 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 8.714e-215 677.0
EH1_k127_1369883_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003869 278.0
EH1_k127_1369883_2 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000000000000000000000000000000005208 203.0
EH1_k127_144474_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000005985 203.0
EH1_k127_144474_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001732 141.0
EH1_k127_144474_2 - - - - 0.00000000000000000000000000000002401 130.0
EH1_k127_144474_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000001305 126.0
EH1_k127_1461851_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 545.0
EH1_k127_1461851_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 487.0
EH1_k127_1461851_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
EH1_k127_1461851_3 4Fe-4S dicluster domain K11260,K14107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004064 278.0
EH1_k127_1461851_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004928 258.0
EH1_k127_1461851_5 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003271 256.0
EH1_k127_1461851_6 PFAM molydopterin dinucleotide-binding region K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.000000000000000000000000000000006679 132.0
EH1_k127_1461851_7 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.0000000000000000001942 96.0
EH1_k127_1461851_8 - K14100 - - 0.000000009053 58.0
EH1_k127_1736483_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 1.536e-236 739.0
EH1_k127_1736483_1 Belongs to the RtcB family K14415 - 6.5.1.3 1.366e-224 704.0
EH1_k127_1736483_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 368.0
EH1_k127_1736483_3 PFAM ABC transporter K16786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000279 242.0
EH1_k127_1736483_4 PFAM ABC transporter related K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000000000007982 238.0
EH1_k127_1736483_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005794 230.0
EH1_k127_1736483_6 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000000000000000000000000000000003135 208.0
EH1_k127_1736483_7 PFAM BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000001228 186.0
EH1_k127_1736483_8 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000001116 134.0
EH1_k127_1736483_9 - - - - 0.0000000000000000001041 90.0
EH1_k127_2146481_0 Flavodoxin domain - - - 0.00000000000000000000000000000000000000002544 158.0
EH1_k127_2146481_1 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000259 143.0
EH1_k127_2146481_2 - - - - 0.00000000000000000000000000000000002324 139.0
EH1_k127_2146481_3 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000001377 121.0
EH1_k127_2146481_4 Protein of unknown function (DUF3795) - - - 0.00000000000002166 73.0
EH1_k127_2146481_5 Histidine kinase-like ATPase domain - - - 0.00000004378 56.0
EH1_k127_2146481_6 PFAM Tetratricopeptide - - - 0.0000005242 61.0
EH1_k127_2154019_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 1.43e-282 878.0
EH1_k127_2154019_1 DEAD DEAH box helicase domain protein K03725 - - 1.623e-282 882.0
EH1_k127_2154019_10 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000008322 233.0
EH1_k127_2154019_11 - - - - 0.0000000000000006435 80.0
EH1_k127_2154019_2 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.148e-235 737.0
EH1_k127_2154019_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 556.0
EH1_k127_2154019_4 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 385.0
EH1_k127_2154019_5 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 389.0
EH1_k127_2154019_6 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 295.0
EH1_k127_2154019_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002298 282.0
EH1_k127_2154019_8 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001517 258.0
EH1_k127_2154019_9 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005724 243.0
EH1_k127_2161927_0 Heat shock 70 kDa protein K04043 - - 9.757e-294 914.0
EH1_k127_2161927_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.059e-249 773.0
EH1_k127_2161927_10 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 295.0
EH1_k127_2161927_11 Protein of unknown function (DUF1646) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007062 282.0
EH1_k127_2161927_12 PFAM Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002273 289.0
EH1_k127_2161927_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009751 268.0
EH1_k127_2161927_14 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002493 246.0
EH1_k127_2161927_15 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
EH1_k127_2161927_16 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000002864 226.0
EH1_k127_2161927_17 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000001534 191.0
EH1_k127_2161927_18 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000009509 189.0
EH1_k127_2161927_19 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000001654 173.0
EH1_k127_2161927_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 5.489e-199 631.0
EH1_k127_2161927_20 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000834 171.0
EH1_k127_2161927_21 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000001489 166.0
EH1_k127_2161927_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000005019 163.0
EH1_k127_2161927_23 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000008565 158.0
EH1_k127_2161927_24 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000004244 137.0
EH1_k127_2161927_25 Protein of unknown function (DUF1646) - - - 0.000000000000000000000000000000004056 131.0
EH1_k127_2161927_26 - - - - 0.00000000000000000000000005573 113.0
EH1_k127_2161927_27 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000006934 64.0
EH1_k127_2161927_28 - - - - 0.0000000324 57.0
EH1_k127_2161927_29 - - - - 0.0000006805 52.0
EH1_k127_2161927_3 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 532.0
EH1_k127_2161927_30 - - - - 0.0001603 46.0
EH1_k127_2161927_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 509.0
EH1_k127_2161927_5 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 419.0
EH1_k127_2161927_6 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 379.0
EH1_k127_2161927_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 385.0
EH1_k127_2161927_8 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 346.0
EH1_k127_2161927_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 301.0
EH1_k127_2187715_0 O-methyltransferase K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
EH1_k127_2187715_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002806 248.0
EH1_k127_2187715_10 TIGRFAM C_GCAxxG_C_C family - - - 0.000000000000000000000000001576 117.0
EH1_k127_2187715_12 sister chromatid segregation - - - 0.0000878 54.0
EH1_k127_2187715_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001817 238.0
EH1_k127_2187715_3 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000008639 227.0
EH1_k127_2187715_4 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.0000000000000000000000000000000000000000000000000000008798 198.0
EH1_k127_2187715_5 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000000000000000109 179.0
EH1_k127_2187715_6 - - - - 0.0000000000000000000000000000000000000000000002363 173.0
EH1_k127_2187715_7 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000007339 171.0
EH1_k127_2187715_8 transcription activator, effector binding - - - 0.000000000000000000000000000000000000000000007358 169.0
EH1_k127_2187715_9 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000006438 154.0
EH1_k127_2197098_0 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 432.0
EH1_k127_2197098_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
EH1_k127_2214893_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 548.0
EH1_k127_2214893_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 481.0
EH1_k127_2214893_10 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000002086 261.0
EH1_k127_2214893_11 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
EH1_k127_2214893_12 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.0000000000000000000000000000000000000000000000000000002488 199.0
EH1_k127_2214893_13 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 - - 0.00000000000000000000000000000000000004253 145.0
EH1_k127_2214893_14 - - - - 0.0001621 46.0
EH1_k127_2214893_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 366.0
EH1_k127_2214893_3 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 362.0
EH1_k127_2214893_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 346.0
EH1_k127_2214893_5 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 339.0
EH1_k127_2214893_6 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 334.0
EH1_k127_2214893_7 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 333.0
EH1_k127_2214893_8 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
EH1_k127_2214893_9 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001472 293.0
EH1_k127_2328751_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.427e-218 688.0
EH1_k127_2328751_1 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 431.0
EH1_k127_2328751_10 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000000000000000000000000000183 181.0
EH1_k127_2328751_11 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000000000000001683 176.0
EH1_k127_2328751_2 PFAM Radical SAM domain protein K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 401.0
EH1_k127_2328751_3 PFAM GTP-binding protein HSR1-related K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 366.0
EH1_k127_2328751_4 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 352.0
EH1_k127_2328751_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 317.0
EH1_k127_2328751_6 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008755 275.0
EH1_k127_2328751_7 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007527 267.0
EH1_k127_2328751_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 257.0
EH1_k127_2328751_9 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 252.0
EH1_k127_2340899_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 516.0
EH1_k127_2340899_1 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 307.0
EH1_k127_2341567_0 PFAM Radical SAM domain protein K02585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 496.0
EH1_k127_2341567_1 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007817 257.0
EH1_k127_2341567_2 - - - - 0.0000000000004482 76.0
EH1_k127_2341567_3 metallopeptidase activity K01126,K01181 - 3.1.4.46,3.2.1.8 0.000000003046 70.0
EH1_k127_2482517_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 552.0
EH1_k127_2482517_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 452.0
EH1_k127_2482517_2 Cysteine-rich small domain K08260 - 3.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 382.0
EH1_k127_2482517_3 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 256.0
EH1_k127_2482517_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000186 213.0
EH1_k127_2482517_5 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000000000000000000000000000000000000000000000001282 202.0
EH1_k127_2482517_6 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000003061 108.0
EH1_k127_2482517_7 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000003154 98.0
EH1_k127_2566113_0 DEAD DEAH box helicase K06877 - - 1.362e-289 907.0
EH1_k127_2566113_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 2.342e-249 779.0
EH1_k127_2566113_10 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002918 253.0
EH1_k127_2566113_11 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000001887 217.0
EH1_k127_2566113_12 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000003525 194.0
EH1_k127_2566113_13 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000001305 185.0
EH1_k127_2566113_14 - - - - 0.00000000000000000000000000000005967 132.0
EH1_k127_2566113_15 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.000000000000000000000000000004492 119.0
EH1_k127_2566113_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.762e-247 775.0
EH1_k127_2566113_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 3.17e-212 665.0
EH1_k127_2566113_4 DNA methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 443.0
EH1_k127_2566113_5 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 378.0
EH1_k127_2566113_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 332.0
EH1_k127_2566113_7 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 336.0
EH1_k127_2566113_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003734 281.0
EH1_k127_2566113_9 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 249.0
EH1_k127_2599418_0 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 516.0
EH1_k127_2599418_1 deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000006828 214.0
EH1_k127_2599418_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.00000000000000000000000000000000004771 143.0
EH1_k127_2604595_0 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 491.0
EH1_k127_2604595_1 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 403.0
EH1_k127_2604595_2 PFAM glutamate synthase alpha subunit domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 340.0
EH1_k127_2683686_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.0 1213.0
EH1_k127_2683686_1 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1183.0
EH1_k127_2683686_10 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 339.0
EH1_k127_2683686_11 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 338.0
EH1_k127_2683686_12 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 323.0
EH1_k127_2683686_13 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 324.0
EH1_k127_2683686_14 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 314.0
EH1_k127_2683686_15 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
EH1_k127_2683686_16 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000009067 239.0
EH1_k127_2683686_17 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000001285 218.0
EH1_k127_2683686_18 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000593 208.0
EH1_k127_2683686_19 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000001633 205.0
EH1_k127_2683686_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1109.0
EH1_k127_2683686_20 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000379 188.0
EH1_k127_2683686_21 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000009363 173.0
EH1_k127_2683686_22 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000001434 158.0
EH1_k127_2683686_23 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000000002047 154.0
EH1_k127_2683686_24 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001257 114.0
EH1_k127_2683686_25 - K00960 - 2.7.7.6 0.00000000000000000000004721 101.0
EH1_k127_2683686_26 - - - - 0.000002242 55.0
EH1_k127_2683686_27 Helix-turn-helix domain - - - 0.00005458 49.0
EH1_k127_2683686_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.592e-295 914.0
EH1_k127_2683686_4 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 1.352e-275 863.0
EH1_k127_2683686_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.44e-218 684.0
EH1_k127_2683686_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.179e-199 628.0
EH1_k127_2683686_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.749e-195 625.0
EH1_k127_2683686_8 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 451.0
EH1_k127_2683686_9 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 358.0
EH1_k127_2800885_0 in RNase L inhibitor, RLI K06174 - - 1.284e-278 869.0
EH1_k127_2800885_1 Domain of unknown function (DUF814) - - - 6.878e-203 650.0
EH1_k127_2800885_10 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000006799 250.0
EH1_k127_2800885_11 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.000000000000000000000000000000000000000000000000000000000000004212 220.0
EH1_k127_2800885_12 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
EH1_k127_2800885_13 Functions by promoting the formation of the first peptide bond K03263 - - 0.0000000000000000000000000000000000000000000000000000000191 198.0
EH1_k127_2800885_14 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000007361 160.0
EH1_k127_2800885_15 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000000000000005488 143.0
EH1_k127_2800885_16 - - - - 0.0000000000000000000000000000001009 130.0
EH1_k127_2800885_17 RNase L inhibitor, RLI - - - 0.0000000000000000000000003884 108.0
EH1_k127_2800885_18 PFAM YHS domain - - - 0.00000000000009133 72.0
EH1_k127_2800885_19 - - - - 0.00000645 52.0
EH1_k127_2800885_2 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 574.0
EH1_k127_2800885_3 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 473.0
EH1_k127_2800885_4 PFAM formate nitrite transporter K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 426.0
EH1_k127_2800885_5 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
EH1_k127_2800885_6 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 344.0
EH1_k127_2800885_7 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 328.0
EH1_k127_2800885_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 320.0
EH1_k127_2800885_9 PFAM metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 295.0
EH1_k127_2979426_0 KH, type 1, domain K07041 - - 0.0 1074.0
EH1_k127_2979426_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 6.805e-294 912.0
EH1_k127_2979426_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000009246 74.0
EH1_k127_2979426_11 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000006237 72.0
EH1_k127_2979426_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 415.0
EH1_k127_2979426_3 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 386.0
EH1_k127_2979426_4 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 314.0
EH1_k127_2979426_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 307.0
EH1_k127_2979426_6 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 314.0
EH1_k127_2979426_7 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000001298 232.0
EH1_k127_2979426_8 COG0589 Universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000000000000000000000000000007506 168.0
EH1_k127_2979426_9 - - - - 0.000000000000000000000000000006971 122.0
EH1_k127_3184506_0 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 466.0
EH1_k127_3184506_1 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 372.0
EH1_k127_3184506_2 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 368.0
EH1_k127_3184506_3 PFAM zinc iron permease K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
EH1_k127_3184506_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000001524 241.0
EH1_k127_3184506_5 Flavodoxin domain - - - 0.000000000000000000000000000000000000000000000002286 177.0
EH1_k127_3184506_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000000003053 125.0
EH1_k127_3184506_7 Protease prsW family - - - 0.0000000000000001303 90.0
EH1_k127_3193161_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.403e-245 764.0
EH1_k127_3193161_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 509.0
EH1_k127_3193161_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 236.0
EH1_k127_3193161_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000001801 228.0
EH1_k127_3193161_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000004522 225.0
EH1_k127_3193161_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000003241 218.0
EH1_k127_3193161_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000008005 212.0
EH1_k127_3193161_15 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000000000000001523 211.0
EH1_k127_3193161_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000003351 201.0
EH1_k127_3193161_17 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000000000000006321 187.0
EH1_k127_3193161_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000000004762 176.0
EH1_k127_3193161_19 PFAM sigma-70 region 4 domain protein K09714 - - 0.000000000000000000000000000000000000000000000004551 175.0
EH1_k127_3193161_2 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 472.0
EH1_k127_3193161_20 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000005656 166.0
EH1_k127_3193161_21 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.00000000000000000000000000000000000000000001993 165.0
EH1_k127_3193161_22 PFAM Ribosomal protein K02912 - - 0.0000000000000000000000000000000000321 140.0
EH1_k127_3193161_23 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000005074 127.0
EH1_k127_3193161_24 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000000002036 102.0
EH1_k127_3193161_25 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000023 106.0
EH1_k127_3193161_26 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000000000000004649 103.0
EH1_k127_3193161_27 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000005169 93.0
EH1_k127_3193161_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 361.0
EH1_k127_3193161_4 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 351.0
EH1_k127_3193161_5 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 347.0
EH1_k127_3193161_6 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 334.0
EH1_k127_3193161_7 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 297.0
EH1_k127_3193161_8 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008514 251.0
EH1_k127_3193161_9 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003785 243.0
EH1_k127_3201359_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 455.0
EH1_k127_3201359_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 349.0
EH1_k127_3201359_10 PFAM CBS domain - - - 0.000000000001804 79.0
EH1_k127_3201359_11 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000003266 66.0
EH1_k127_3201359_12 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K02239 - - 0.0002229 48.0
EH1_k127_3201359_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 301.0
EH1_k127_3201359_3 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 302.0
EH1_k127_3201359_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 291.0
EH1_k127_3201359_5 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008781 262.0
EH1_k127_3201359_6 hydrolase K04794 - 3.1.1.29 0.00000000000000000000000000000000000000000000002641 173.0
EH1_k127_3201359_7 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000000000000000007459 155.0
EH1_k127_3201359_8 - - - - 0.000000000000000000000000000006095 120.0
EH1_k127_3201359_9 signal transduction protein with CBS domains - - - 0.000000000000000000000004545 115.0
EH1_k127_3240730_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 517.0
EH1_k127_3240730_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 324.0
EH1_k127_3240730_2 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000002733 231.0
EH1_k127_3240730_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000002566 177.0
EH1_k127_3264267_0 peptidyl-tyrosine sulfation - - - 5.166e-258 836.0
EH1_k127_3264267_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.76e-231 721.0
EH1_k127_3264267_10 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001799 224.0
EH1_k127_3264267_11 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000001455 225.0
EH1_k127_3264267_12 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000000000000000000000000000002266 211.0
EH1_k127_3264267_13 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000005585 204.0
EH1_k127_3264267_14 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000003467 201.0
EH1_k127_3264267_15 Belongs to the UPF0305 family - - - 0.00000000000000000000000000000000000000000000000000003144 192.0
EH1_k127_3264267_16 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000006934 168.0
EH1_k127_3264267_17 - - - - 0.0000000000000000000000000001561 121.0
EH1_k127_3264267_18 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000000000005094 115.0
EH1_k127_3264267_19 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000003013 109.0
EH1_k127_3264267_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 3.768e-231 720.0
EH1_k127_3264267_20 PFAM Transcriptional regulator PadR-like family - - - 0.0000001093 63.0
EH1_k127_3264267_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 3.601e-226 706.0
EH1_k127_3264267_4 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 603.0
EH1_k127_3264267_5 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 477.0
EH1_k127_3264267_6 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 436.0
EH1_k127_3264267_7 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 421.0
EH1_k127_3264267_8 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 310.0
EH1_k127_3264267_9 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001405 263.0
EH1_k127_3267261_0 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000001379 175.0
EH1_k127_3267261_1 - - - - 0.0000000000002478 73.0
EH1_k127_3267261_2 SMART Tetratricopeptide domain protein - - - 0.0000001333 63.0
EH1_k127_3284679_0 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 501.0
EH1_k127_3284679_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 507.0
EH1_k127_3284679_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001589 264.0
EH1_k127_3284679_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000008489 169.0
EH1_k127_3284679_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000212 108.0
EH1_k127_3311398_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 510.0
EH1_k127_3311398_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 390.0
EH1_k127_3311398_2 PFAM Radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001773 258.0
EH1_k127_3311398_3 Uncharacterised protein family UPF0058 - - - 0.00000000000000000000000000000000000000004523 153.0
EH1_k127_3311398_4 Belongs to the UPF0235 family K09131 - - 0.0000000000000000005432 90.0
EH1_k127_3311400_0 Uncharacterized protein conserved in archaea (DUF2114) - - - 6.195e-250 778.0
EH1_k127_3311400_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.783e-198 622.0
EH1_k127_3311400_2 PFAM Radical SAM domain protein K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 609.0
EH1_k127_3311400_3 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 598.0
EH1_k127_3311400_4 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 413.0
EH1_k127_3311400_5 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 411.0
EH1_k127_3311400_6 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000000000003188 214.0
EH1_k127_3311400_7 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000000000000000000000004369 184.0
EH1_k127_3311400_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000641 179.0
EH1_k127_3311400_9 - - - - 0.0000000000000000000000002328 107.0
EH1_k127_3323974_0 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 555.0
EH1_k127_3323974_1 - K14093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 248.0
EH1_k127_3323974_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000003688 151.0
EH1_k127_3323974_3 Small multi-drug export protein - - - 0.000000000000000000000000000000004478 137.0
EH1_k127_3323974_4 Predicted membrane protein (DUF2109) K14094 - - 0.0000000000000000004014 92.0
EH1_k127_3343421_0 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 459.0
EH1_k127_3343421_1 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 429.0
EH1_k127_3343421_10 - - - - 0.000000000000000000000000000000000000000000000000000000112 210.0
EH1_k127_3343421_11 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000000000000000000000000003412 177.0
EH1_k127_3343421_12 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000001098 164.0
EH1_k127_3343421_13 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000007724 156.0
EH1_k127_3343421_14 Protein of unknown function (DUF2769) - - - 0.00000000000000000000000002823 110.0
EH1_k127_3343421_15 PFAM response regulator receiver K11443 - - 0.00000000000000000000000007932 111.0
EH1_k127_3343421_16 - - - - 0.00000000000000000000000008083 112.0
EH1_k127_3343421_17 E-Z type HEAT repeats - - - 0.000000000005925 70.0
EH1_k127_3343421_2 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
EH1_k127_3343421_3 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 374.0
EH1_k127_3343421_4 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 347.0
EH1_k127_3343421_5 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 327.0
EH1_k127_3343421_6 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000889 284.0
EH1_k127_3343421_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 286.0
EH1_k127_3343421_8 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000251 211.0
EH1_k127_3343421_9 PFAM TrkA-C domain K07228 - - 0.000000000000000000000000000000000000000000000000000000000006819 211.0
EH1_k127_3348407_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 561.0
EH1_k127_3348407_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 462.0
EH1_k127_3348407_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 384.0
EH1_k127_3348407_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 368.0
EH1_k127_3348407_4 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000003582 94.0
EH1_k127_3370388_0 acid binding OB-fold tRNA helicase-type K07463 - - 2.863e-278 869.0
EH1_k127_3370388_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 604.0
EH1_k127_3370388_10 - - - - 0.0000000000000000000000000002706 116.0
EH1_k127_3370388_11 - - - - 0.0000000000000000005606 88.0
EH1_k127_3370388_12 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000000000000000002917 86.0
EH1_k127_3370388_13 - - - - 0.000000000000000004665 89.0
EH1_k127_3370388_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 572.0
EH1_k127_3370388_3 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 416.0
EH1_k127_3370388_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 414.0
EH1_k127_3370388_5 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 400.0
EH1_k127_3370388_6 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000001235 230.0
EH1_k127_3370388_7 adenyl ribonucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000002027 205.0
EH1_k127_3370388_8 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000584 186.0
EH1_k127_3370388_9 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000004621 143.0
EH1_k127_3456482_0 Belongs to the MCM family K10726 - - 7.436e-302 939.0
EH1_k127_3456482_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 499.0
EH1_k127_3456482_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 374.0
EH1_k127_3456482_3 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 331.0
EH1_k127_3456482_4 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 310.0
EH1_k127_3456482_5 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000004406 132.0
EH1_k127_3456482_6 protein conserved in archaea K09746 - - 0.00000000000000000000000000000004797 132.0
EH1_k127_3456482_7 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000008795 112.0
EH1_k127_3456482_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000001279 63.0
EH1_k127_3468057_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1309.0
EH1_k127_3468057_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.123e-305 949.0
EH1_k127_3468057_10 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000007837 188.0
EH1_k127_3468057_11 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000006665 183.0
EH1_k127_3468057_12 - - - - 0.000000000000000000000000000000000000000000000002286 183.0
EH1_k127_3468057_13 Roadblock LC7 K07131 - - 0.000000000000000000000000000000000000000000004417 165.0
EH1_k127_3468057_14 - - - - 0.000000000000000000000000000000000000000006191 161.0
EH1_k127_3468057_15 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000000000000000004891 138.0
EH1_k127_3468057_16 - - - - 0.000000000000000000000000003406 113.0
EH1_k127_3468057_17 - - - - 0.00000003724 63.0
EH1_k127_3468057_2 PFAM type II secretion system protein E K07332 - - 6.569e-282 887.0
EH1_k127_3468057_3 PFAM PilT protein domain protein K06865 - - 9.191e-281 874.0
EH1_k127_3468057_4 TIGRFAM cell division ATPase MinD K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
EH1_k127_3468057_5 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 371.0
EH1_k127_3468057_6 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 347.0
EH1_k127_3468057_7 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 342.0
EH1_k127_3468057_8 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 341.0
EH1_k127_3468057_9 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000000000000000000000004356 220.0
EH1_k127_3487804_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 458.0
EH1_k127_3487804_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 455.0
EH1_k127_3487804_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 443.0
EH1_k127_3487804_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 434.0
EH1_k127_3487804_4 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 425.0
EH1_k127_3487804_5 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 417.0
EH1_k127_3487804_6 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
EH1_k127_3487804_7 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000365 287.0
EH1_k127_3542626_0 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 420.0
EH1_k127_3542626_1 PFAM amino acid-binding ACT domain protein K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 317.0
EH1_k127_3542626_2 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 298.0
EH1_k127_3542626_3 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000003193 241.0
EH1_k127_3542626_4 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000005857 236.0
EH1_k127_3542626_5 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000000002962 146.0
EH1_k127_3542626_6 Phage integrase family - - - 0.00001748 50.0
EH1_k127_3552407_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.184e-290 908.0
EH1_k127_3552407_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.348e-275 866.0
EH1_k127_3552407_10 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 526.0
EH1_k127_3552407_11 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 502.0
EH1_k127_3552407_12 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 496.0
EH1_k127_3552407_13 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 481.0
EH1_k127_3552407_14 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 452.0
EH1_k127_3552407_15 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 421.0
EH1_k127_3552407_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 387.0
EH1_k127_3552407_17 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 366.0
EH1_k127_3552407_18 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 339.0
EH1_k127_3552407_19 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 321.0
EH1_k127_3552407_2 SMART Elongator protein 3 MiaB NifB - - - 2.5e-259 812.0
EH1_k127_3552407_20 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 305.0
EH1_k127_3552407_21 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 273.0
EH1_k127_3552407_22 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
EH1_k127_3552407_23 KH domain protein K06961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 255.0
EH1_k127_3552407_24 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000002866 243.0
EH1_k127_3552407_25 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
EH1_k127_3552407_26 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.00000000000000000000000000000000000000000000000000000000000000006263 227.0
EH1_k127_3552407_27 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000000000000000000000234 220.0
EH1_k127_3552407_28 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000004757 211.0
EH1_k127_3552407_29 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000001468 196.0
EH1_k127_3552407_3 Involved in regulation of DNA replication K10725 - - 9.056e-209 655.0
EH1_k127_3552407_30 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000004547 197.0
EH1_k127_3552407_31 Flavodoxin - - - 0.00000000000000000000000000000000000001708 149.0
EH1_k127_3552407_32 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000000000000000000000002009 141.0
EH1_k127_3552407_33 nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000003401 135.0
EH1_k127_3552407_34 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000000000000000000003515 115.0
EH1_k127_3552407_35 protein conserved in archaea - - - 0.0000000000000000000000000004458 116.0
EH1_k127_3552407_36 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000001287 110.0
EH1_k127_3552407_37 - - - - 0.00000000000000000000002222 111.0
EH1_k127_3552407_38 - - - - 0.0000000000000000000002625 104.0
EH1_k127_3552407_39 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000001284 95.0
EH1_k127_3552407_4 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 589.0
EH1_k127_3552407_40 transcriptional regulators K03724 - - 0.00000000000000000006381 91.0
EH1_k127_3552407_41 Belongs to the UPF0434 family - - - 0.0000000000000000002154 88.0
EH1_k127_3552407_42 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000001069 86.0
EH1_k127_3552407_43 Peptidase family M23 - - - 0.000000114 55.0
EH1_k127_3552407_44 COG0457 FOG TPR repeat - - - 0.000003982 53.0
EH1_k127_3552407_45 - - - - 0.0007178 45.0
EH1_k127_3552407_5 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 584.0
EH1_k127_3552407_6 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 587.0
EH1_k127_3552407_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 556.0
EH1_k127_3552407_8 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 543.0
EH1_k127_3552407_9 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 548.0
EH1_k127_3568407_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 1.47e-198 622.0
EH1_k127_3568407_1 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000000000000000002305 232.0
EH1_k127_3568407_2 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000002017 195.0
EH1_k127_3568407_3 B-block binding subunit of TFIIIC - - - 0.0000000000000000000000000000000000000000000004251 168.0
EH1_k127_3568407_4 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000488 147.0
EH1_k127_3568407_5 - - - - 0.00000000000000000000000000000001355 133.0
EH1_k127_3568407_6 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000001682 125.0
EH1_k127_3568407_7 PBS lyase HEAT-like repeat - - - 0.0000000000000000007552 96.0
EH1_k127_3592059_0 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 398.0
EH1_k127_3592059_1 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000001351 180.0
EH1_k127_3592059_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000000486 174.0
EH1_k127_3661294_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 541.0
EH1_k127_3661294_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 518.0
EH1_k127_3661294_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 469.0
EH1_k127_3661294_3 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 451.0
EH1_k127_3661294_4 Domain of unknown function (DUF1743) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 413.0
EH1_k127_3661294_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 347.0
EH1_k127_3661294_6 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003745 292.0
EH1_k127_3661294_7 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000002773 225.0
EH1_k127_3661294_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.0000000000000000000000000000000000000000001735 161.0
EH1_k127_3661294_9 PFAM Radical SAM - - - 0.0000000003163 63.0
EH1_k127_4258111_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 516.0
EH1_k127_4258111_1 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 515.0
EH1_k127_4258111_10 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 257.0
EH1_k127_4258111_11 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000001746 237.0
EH1_k127_4258111_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000001635 221.0
EH1_k127_4258111_13 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000000000000000001268 157.0
EH1_k127_4258111_14 - - - - 0.0000000000000000000000000000000001689 137.0
EH1_k127_4258111_15 4Fe-4S dicluster domain - - - 0.0000000000000000002417 89.0
EH1_k127_4258111_16 structural constituent of ribosome K02962 - - 0.0000000000000001664 80.0
EH1_k127_4258111_17 - - - - 0.0001491 49.0
EH1_k127_4258111_2 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 452.0
EH1_k127_4258111_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 439.0
EH1_k127_4258111_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 429.0
EH1_k127_4258111_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 376.0
EH1_k127_4258111_6 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 381.0
EH1_k127_4258111_7 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 357.0
EH1_k127_4258111_8 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 340.0
EH1_k127_4258111_9 sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 339.0
EH1_k127_4270264_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.307e-241 750.0
EH1_k127_4270264_1 PFAM aminotransferase class V - - - 1.333e-202 638.0
EH1_k127_4270264_10 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000018 251.0
EH1_k127_4270264_11 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001855 256.0
EH1_k127_4270264_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000001663 222.0
EH1_k127_4270264_13 PFAM Ribonuclease III - - - 0.000000000000000000000000000000000000000000000000000000000001948 216.0
EH1_k127_4270264_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000002565 196.0
EH1_k127_4270264_15 Yip1 domain - - - 0.00000000000000000000000000000000000000000002241 169.0
EH1_k127_4270264_16 SMART Excinuclease ABC, C subunit - - - 0.0000000000000000000000000000000000000000001323 163.0
EH1_k127_4270264_17 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000000007997 121.0
EH1_k127_4270264_18 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000044 106.0
EH1_k127_4270264_19 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000818 81.0
EH1_k127_4270264_2 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 599.0
EH1_k127_4270264_20 Protein of unknown function (DUF2953) - - - 0.000000000005552 74.0
EH1_k127_4270264_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 542.0
EH1_k127_4270264_4 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 540.0
EH1_k127_4270264_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 490.0
EH1_k127_4270264_6 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 318.0
EH1_k127_4270264_7 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 312.0
EH1_k127_4270264_8 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 308.0
EH1_k127_4270264_9 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000899 261.0
EH1_k127_4395686_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1744.0
EH1_k127_4395686_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 382.0
EH1_k127_4395686_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 312.0
EH1_k127_4395686_3 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009068 269.0
EH1_k127_4395686_4 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000001164 166.0
EH1_k127_4395686_5 - - - - 0.0000000000000000000001485 105.0
EH1_k127_4395686_6 PFAM PBS lyase HEAT-like repeat - - - 0.0004679 46.0
EH1_k127_4424714_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 9.259e-245 763.0
EH1_k127_4424714_1 - - - - 0.0000007588 51.0
EH1_k127_4446869_0 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 564.0
EH1_k127_4446869_1 Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 407.0
EH1_k127_4446869_2 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 351.0
EH1_k127_4446869_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000000000000779 221.0
EH1_k127_4446869_4 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000001856 168.0
EH1_k127_4446869_5 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000003228 154.0
EH1_k127_4446869_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000002825 129.0
EH1_k127_4452658_0 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 1.911e-269 833.0
EH1_k127_4452658_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.455e-244 766.0
EH1_k127_4452658_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 382.0
EH1_k127_4472548_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 582.0
EH1_k127_4472548_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 331.0
EH1_k127_4472548_2 amino acid K16263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
EH1_k127_4472548_3 small multi-drug export - - - 0.000000000000000000000000000000000000000000000000000005557 195.0
EH1_k127_4472548_4 PP-loop domain protein K06864 - - 0.000000000000000000000000001555 116.0
EH1_k127_4472548_5 SpoVT / AbrB like domain - - - 0.00000000000000000000000001963 110.0
EH1_k127_4472548_6 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000001841 83.0
EH1_k127_4488553_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 600.0
EH1_k127_4488553_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 284.0
EH1_k127_4488553_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001972 229.0
EH1_k127_4488553_3 Helix-turn-helix domain protein K03627 - - 0.000000000000000000000000000000000000000000000005338 177.0
EH1_k127_4488553_4 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000002726 174.0
EH1_k127_4488553_5 Pfam:Pyridox_oxidase - - - 0.000000000000003279 80.0
EH1_k127_4490286_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 1.766e-227 709.0
EH1_k127_4490286_1 membrane K09167 - - 0.000000000000000000000000000000000000000000000002755 179.0
EH1_k127_4490286_2 - K00960 - 2.7.7.6 0.00000000000000000000004721 101.0
EH1_k127_4524408_0 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 531.0
EH1_k127_4524408_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 328.0
EH1_k127_4524408_2 membrane K09167 - - 0.00000000000000000000000000000000000000000000001328 177.0
EH1_k127_4600565_0 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 500.0
EH1_k127_4600565_1 Rhodanese domain protein K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000002975 200.0
EH1_k127_4600771_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1125.0
EH1_k127_4600771_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 510.0
EH1_k127_4600771_2 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 272.0
EH1_k127_4600771_3 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000205 177.0
EH1_k127_4600771_4 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000001087 155.0
EH1_k127_4600771_5 - - - - 0.000000000000000000000000000000003507 132.0
EH1_k127_4600771_6 TIR domain - - - 0.0000000005616 67.0
EH1_k127_4717859_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 368.0
EH1_k127_4717859_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 310.0
EH1_k127_4717859_2 Bacterial transcription activator, effector binding domain - - - 0.000000000000000001659 92.0
EH1_k127_4717859_3 - - - - 0.00000000001078 66.0
EH1_k127_47445_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 9.015e-270 841.0
EH1_k127_47445_1 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 8.598e-218 681.0
EH1_k127_47445_10 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 422.0
EH1_k127_47445_11 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 422.0
EH1_k127_47445_12 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 410.0
EH1_k127_47445_13 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 407.0
EH1_k127_47445_14 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 312.0
EH1_k127_47445_15 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 298.0
EH1_k127_47445_16 cytidyltransferase-related domain K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001583 280.0
EH1_k127_47445_17 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000459 198.0
EH1_k127_47445_18 COG1202 Superfamily II helicase, archaea-specific - - - 0.000000000000000000000000000000000000000000000000000006967 193.0
EH1_k127_47445_19 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000004809 184.0
EH1_k127_47445_2 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 591.0
EH1_k127_47445_20 - - - - 0.0000000000000000000000000000000000000000000006629 168.0
EH1_k127_47445_21 - - - - 0.0000000000000000000000000000001009 130.0
EH1_k127_47445_22 - - - - 0.00000000000000000000000001382 111.0
EH1_k127_47445_23 - - - - 0.0000000000002022 75.0
EH1_k127_47445_24 - K06868 - 2.5.1.73 0.0000001494 57.0
EH1_k127_47445_3 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 559.0
EH1_k127_47445_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 548.0
EH1_k127_47445_5 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 497.0
EH1_k127_47445_6 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 516.0
EH1_k127_47445_7 MviN-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 440.0
EH1_k127_47445_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 435.0
EH1_k127_47445_9 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 430.0
EH1_k127_4817928_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.447e-303 950.0
EH1_k127_4817928_1 AMP-binding enzyme - - - 4.154e-222 695.0
EH1_k127_4817928_10 PFAM peptidase U32 K08303 - - 0.000000000000000000004939 96.0
EH1_k127_4817928_11 PFAM Radical SAM domain protein - - - 0.0001409 46.0
EH1_k127_4817928_2 - - - - 0.00000000000000000000000000000000000000000000000000000001682 199.0
EH1_k127_4817928_3 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000001065 183.0
EH1_k127_4817928_4 Belongs to the UPF0216 family K09737 - - 0.000000000000000000000000000000000000000000001277 168.0
EH1_k127_4817928_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000002336 160.0
EH1_k127_4817928_6 PFAM phosphatidate cytidylyltransferase - - - 0.000000000000000000000000000000000000003656 154.0
EH1_k127_4817928_7 - - - - 0.00000000000000000000000000000000001532 135.0
EH1_k127_4817928_8 - K00960 - 2.7.7.6 0.00000000000000000000000000000005234 125.0
EH1_k127_4817928_9 - - - - 0.00000000000000000000001422 108.0
EH1_k127_4859512_0 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 415.0
EH1_k127_4859512_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000009037 107.0
EH1_k127_51163_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 1.533e-199 632.0
EH1_k127_51163_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 458.0
EH1_k127_51163_2 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000002796 225.0
EH1_k127_51163_3 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000855 221.0
EH1_k127_514024_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0 1038.0
EH1_k127_514024_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.478e-250 781.0
EH1_k127_514024_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 563.0
EH1_k127_514024_11 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 561.0
EH1_k127_514024_12 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 548.0
EH1_k127_514024_13 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 539.0
EH1_k127_514024_14 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 526.0
EH1_k127_514024_15 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 488.0
EH1_k127_514024_16 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 483.0
EH1_k127_514024_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 472.0
EH1_k127_514024_18 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 466.0
EH1_k127_514024_19 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 446.0
EH1_k127_514024_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 3.187e-223 704.0
EH1_k127_514024_20 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 434.0
EH1_k127_514024_21 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 418.0
EH1_k127_514024_22 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 413.0
EH1_k127_514024_23 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 410.0
EH1_k127_514024_24 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 402.0
EH1_k127_514024_25 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 393.0
EH1_k127_514024_26 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 379.0
EH1_k127_514024_27 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 362.0
EH1_k127_514024_28 PFAM oxidoreductase nitrogenase, component 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 355.0
EH1_k127_514024_29 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 348.0
EH1_k127_514024_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.402e-221 699.0
EH1_k127_514024_30 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 339.0
EH1_k127_514024_31 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 327.0
EH1_k127_514024_32 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 312.0
EH1_k127_514024_33 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 311.0
EH1_k127_514024_34 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 282.0
EH1_k127_514024_35 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
EH1_k127_514024_36 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001309 274.0
EH1_k127_514024_37 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009245 272.0
EH1_k127_514024_38 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002484 273.0
EH1_k127_514024_39 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007507 268.0
EH1_k127_514024_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.988e-213 668.0
EH1_k127_514024_40 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
EH1_k127_514024_41 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000001398 244.0
EH1_k127_514024_42 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000007971 225.0
EH1_k127_514024_43 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000001572 228.0
EH1_k127_514024_44 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000001401 210.0
EH1_k127_514024_45 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000003334 211.0
EH1_k127_514024_46 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000000000000008375 196.0
EH1_k127_514024_47 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000000000000000000281 190.0
EH1_k127_514024_48 Domain of unknown function (DUF1890) - - - 0.000000000000000000000000000000000000000000000000003197 185.0
EH1_k127_514024_49 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000003666 183.0
EH1_k127_514024_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.571e-209 657.0
EH1_k127_514024_50 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000001389 176.0
EH1_k127_514024_51 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000001513 171.0
EH1_k127_514024_52 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000001951 166.0
EH1_k127_514024_53 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000000000004249 162.0
EH1_k127_514024_54 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000000000000000000000000000000000638 155.0
EH1_k127_514024_55 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000006646 147.0
EH1_k127_514024_56 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000000000000000000007642 145.0
EH1_k127_514024_57 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000002469 134.0
EH1_k127_514024_58 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000000003921 132.0
EH1_k127_514024_59 - - - - 0.0000000000000000000000000000000008133 140.0
EH1_k127_514024_6 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 2.739e-196 617.0
EH1_k127_514024_60 - - - - 0.000000000000000000000000000000001421 133.0
EH1_k127_514024_61 Domain of unknown function (DUF1894) - - - 0.0000000000000000000000000000004643 124.0
EH1_k127_514024_62 - - - - 0.000000000000000000000000000000739 126.0
EH1_k127_514024_63 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000007276 125.0
EH1_k127_514024_64 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000001696 107.0
EH1_k127_514024_65 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000005367 107.0
EH1_k127_514024_66 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000002182 105.0
EH1_k127_514024_67 PBS lyase HEAT-like repeat - - - 0.00000000000000000000004221 111.0
EH1_k127_514024_68 Transcriptional regulator K07108 - - 0.0000000000000000000001128 101.0
EH1_k127_514024_69 rubredoxin - - - 0.0000000000000000000002626 98.0
EH1_k127_514024_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 596.0
EH1_k127_514024_70 CRS1_YhbY K07574 - - 0.0000000000000000000005069 97.0
EH1_k127_514024_71 - - - - 0.000000000000000000001866 100.0
EH1_k127_514024_72 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000001635 91.0
EH1_k127_514024_73 structural constituent of ribosome K02924 - - 0.0000000000000000002417 89.0
EH1_k127_514024_74 - - - - 0.000000000000000005051 90.0
EH1_k127_514024_75 PFAM Ribosomal LX protein K02944 - - 0.000000000008388 69.0
EH1_k127_514024_76 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00001304 49.0
EH1_k127_514024_77 COG3364 Zn-ribbon containing protein K07163 - - 0.0003928 52.0
EH1_k127_514024_78 Rubredoxin - - - 0.0005734 46.0
EH1_k127_514024_8 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 584.0
EH1_k127_514024_9 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 576.0
EH1_k127_5149216_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1066.0
EH1_k127_5149216_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 5.053e-243 765.0
EH1_k127_5149216_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000003229 85.0
EH1_k127_5149216_11 - - - - 0.000000000000001731 79.0
EH1_k127_5149216_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 565.0
EH1_k127_5149216_3 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 409.0
EH1_k127_5149216_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 382.0
EH1_k127_5149216_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 374.0
EH1_k127_5149216_6 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 336.0
EH1_k127_5149216_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006898 250.0
EH1_k127_5149216_8 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000007681 228.0
EH1_k127_5149216_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000000007642 124.0
EH1_k127_5269003_0 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
EH1_k127_5269003_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 308.0
EH1_k127_5269003_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
EH1_k127_5269003_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000003988 179.0
EH1_k127_5349794_0 Domain of unknown function DUF87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 503.0
EH1_k127_5349794_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 446.0
EH1_k127_5349794_10 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000002374 178.0
EH1_k127_5349794_11 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000000000000000000002167 145.0
EH1_k127_5349794_12 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.00000000000004407 78.0
EH1_k127_5349794_13 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000002489 71.0
EH1_k127_5349794_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 407.0
EH1_k127_5349794_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 391.0
EH1_k127_5349794_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 375.0
EH1_k127_5349794_5 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 328.0
EH1_k127_5349794_6 FHA domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000017 273.0
EH1_k127_5349794_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 257.0
EH1_k127_5349794_8 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000000000000000000000000000000000000000003777 216.0
EH1_k127_5349794_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000001124 191.0
EH1_k127_5365436_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
EH1_k127_5365436_1 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000491 258.0
EH1_k127_5365436_2 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000003018 102.0
EH1_k127_5365436_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000007318 83.0
EH1_k127_5373336_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.959e-244 758.0
EH1_k127_5373336_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 591.0
EH1_k127_5373336_2 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 591.0
EH1_k127_5373336_3 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000004623 213.0
EH1_k127_5373336_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000005847 107.0
EH1_k127_5373336_5 Hsp20/alpha crystallin family K13993 - - 0.000000000369 67.0
EH1_k127_5379826_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.801e-275 854.0
EH1_k127_5379826_1 PFAM dihydropteroate synthase, DHPS - - - 5.65e-200 633.0
EH1_k127_5379826_10 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000006465 204.0
EH1_k127_5379826_11 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.000000000000000000000000000000000000000000000000003599 183.0
EH1_k127_5379826_12 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000004707 135.0
EH1_k127_5379826_13 Protein of unknown function (DUF2769) - - - 0.0000000000000000000001334 101.0
EH1_k127_5379826_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 583.0
EH1_k127_5379826_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 501.0
EH1_k127_5379826_4 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 486.0
EH1_k127_5379826_5 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 435.0
EH1_k127_5379826_6 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 374.0
EH1_k127_5379826_7 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 343.0
EH1_k127_5379826_8 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 293.0
EH1_k127_5379826_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009079 279.0
EH1_k127_5380493_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009936 299.0
EH1_k127_5380493_1 response regulator - - - 0.000000000000000000000000000000000000000003728 158.0
EH1_k127_5380493_2 Pas domain - - - 0.000000000000000005056 85.0
EH1_k127_5446760_0 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 602.0
EH1_k127_5446760_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 370.0
EH1_k127_5446760_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 353.0
EH1_k127_5446760_4 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001138 248.0
EH1_k127_5446760_5 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000009595 193.0
EH1_k127_5446760_6 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000005867 73.0
EH1_k127_5541748_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.032e-255 796.0
EH1_k127_5541748_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 1.587e-196 619.0
EH1_k127_5541748_10 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003015 264.0
EH1_k127_5541748_11 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008503 265.0
EH1_k127_5541748_12 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005527 249.0
EH1_k127_5541748_13 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002119 197.0
EH1_k127_5541748_14 Thioredoxin - - - 0.000000000000000000000000000000000000000000004722 166.0
EH1_k127_5541748_15 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000003714 148.0
EH1_k127_5541748_16 - K03686 - - 0.00000000000000000002527 91.0
EH1_k127_5541748_2 PFAM glutamate--cysteine ligase, GCS2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 435.0
EH1_k127_5541748_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 424.0
EH1_k127_5541748_4 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 404.0
EH1_k127_5541748_5 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 324.0
EH1_k127_5541748_6 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 295.0
EH1_k127_5541748_7 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 291.0
EH1_k127_5541748_8 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 284.0
EH1_k127_5541748_9 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003599 293.0
EH1_k127_5592297_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 338.0
EH1_k127_5592297_1 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001565 248.0
EH1_k127_5592297_2 Protein phosphatase 2C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003623 248.0
EH1_k127_5592297_3 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000007505 119.0
EH1_k127_5627768_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1021.0
EH1_k127_5627768_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.19e-316 975.0
EH1_k127_5627768_10 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.165e-218 691.0
EH1_k127_5627768_11 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 1.563e-216 681.0
EH1_k127_5627768_12 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.069e-214 675.0
EH1_k127_5627768_13 V-type ATPase 116kDa subunit family K02123 - - 7.756e-207 661.0
EH1_k127_5627768_14 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 604.0
EH1_k127_5627768_15 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 579.0
EH1_k127_5627768_16 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 564.0
EH1_k127_5627768_17 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 520.0
EH1_k127_5627768_18 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 514.0
EH1_k127_5627768_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 486.0
EH1_k127_5627768_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.529e-292 904.0
EH1_k127_5627768_20 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 465.0
EH1_k127_5627768_21 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 452.0
EH1_k127_5627768_22 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 451.0
EH1_k127_5627768_23 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 433.0
EH1_k127_5627768_24 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 418.0
EH1_k127_5627768_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 362.0
EH1_k127_5627768_26 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 345.0
EH1_k127_5627768_27 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 349.0
EH1_k127_5627768_28 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 349.0
EH1_k127_5627768_29 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 324.0
EH1_k127_5627768_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.413e-268 829.0
EH1_k127_5627768_30 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 331.0
EH1_k127_5627768_31 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 319.0
EH1_k127_5627768_32 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 315.0
EH1_k127_5627768_33 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 310.0
EH1_k127_5627768_34 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 301.0
EH1_k127_5627768_35 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 302.0
EH1_k127_5627768_36 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 284.0
EH1_k127_5627768_37 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005744 268.0
EH1_k127_5627768_38 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001598 250.0
EH1_k127_5627768_39 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
EH1_k127_5627768_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 7.899e-252 782.0
EH1_k127_5627768_40 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001283 247.0
EH1_k127_5627768_41 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000003176 228.0
EH1_k127_5627768_42 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
EH1_k127_5627768_43 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
EH1_k127_5627768_44 PFAM PUA domain containing protein K07575 - - 0.000000000000000000000000000000000000000000000000000000006721 202.0
EH1_k127_5627768_45 Pfam:DUF552 K09152 - - 0.000000000000000000000000000000000000000000000000000001188 194.0
EH1_k127_5627768_46 ZPR1-related zinc finger protein K06874 - - 0.00000000000000000000000000000000000000000000001166 179.0
EH1_k127_5627768_47 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000004299 173.0
EH1_k127_5627768_48 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000033 172.0
EH1_k127_5627768_49 - - - - 0.000000000000000000000000000000000000000000001264 169.0
EH1_k127_5627768_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.617e-245 787.0
EH1_k127_5627768_50 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000005891 166.0
EH1_k127_5627768_51 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000009692 162.0
EH1_k127_5627768_52 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000000000000000000188 163.0
EH1_k127_5627768_53 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000000003237 132.0
EH1_k127_5627768_54 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000004645 128.0
EH1_k127_5627768_55 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000009335 122.0
EH1_k127_5627768_56 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000007449 120.0
EH1_k127_5627768_57 binds to the 23S rRNA K02922 - - 0.000000000000000000000000001677 111.0
EH1_k127_5627768_58 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000000003259 111.0
EH1_k127_5627768_59 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000000002458 109.0
EH1_k127_5627768_6 PFAM chaperonin Cpn60 TCP-1 K22447 - - 7.179e-239 749.0
EH1_k127_5627768_60 Transglutaminase-like superfamily - - - 0.000000000000000000000002003 118.0
EH1_k127_5627768_61 - - - - 0.000000000000000000001979 93.0
EH1_k127_5627768_62 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000003174 94.0
EH1_k127_5627768_63 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000003336 101.0
EH1_k127_5627768_64 ATP synthase subunit C K02124 - - 0.00000000000000000005475 92.0
EH1_k127_5627768_65 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.0000000000000000006593 89.0
EH1_k127_5627768_66 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.000000000000003514 76.0
EH1_k127_5627768_68 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000005289 72.0
EH1_k127_5627768_69 PHP domain protein - - - 0.000000000001666 68.0
EH1_k127_5627768_7 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 7.396e-236 745.0
EH1_k127_5627768_70 SigmaK-factor processing regulatory protein BofA - - - 0.00000000001049 68.0
EH1_k127_5627768_71 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000001135 64.0
EH1_k127_5627768_72 PFAM Linocin_M18 bacteriocin protein - - - 0.0000000001173 63.0
EH1_k127_5627768_73 - - - - 0.00000003596 63.0
EH1_k127_5627768_74 PHP-associated - - - 0.00000005527 57.0
EH1_k127_5627768_75 - - - - 0.000004945 53.0
EH1_k127_5627768_76 PBS lyase HEAT-like repeat - - - 0.00006357 53.0
EH1_k127_5627768_77 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0001187 48.0
EH1_k127_5627768_78 H subunit K02107 - - 0.0006253 47.0
EH1_k127_5627768_8 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 9.02e-230 729.0
EH1_k127_5627768_9 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.804e-229 728.0
EH1_k127_5668722_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 521.0
EH1_k127_5668722_1 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000585 174.0
EH1_k127_5668722_2 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000004153 162.0
EH1_k127_5668722_3 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000004709 129.0
EH1_k127_5899371_0 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 385.0
EH1_k127_5899371_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 343.0
EH1_k127_5899371_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 288.0
EH1_k127_5899371_3 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000003624 219.0
EH1_k127_5899371_4 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000009377 175.0
EH1_k127_5899371_5 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000006871 135.0
EH1_k127_5908023_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1084.0
EH1_k127_5908023_1 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 280.0
EH1_k127_5908023_2 protein conserved in archaea K09746 - - 0.000001456 54.0
EH1_k127_6016347_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 2.942e-264 827.0
EH1_k127_6016347_1 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 364.0
EH1_k127_6016347_2 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 338.0
EH1_k127_6016347_3 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 299.0
EH1_k127_6016347_4 PFAM Amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000008473 226.0
EH1_k127_6016347_5 PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000001981 207.0
EH1_k127_6016347_6 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000006124 173.0
EH1_k127_6016347_7 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00002263 52.0
EH1_k127_6076648_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 8.526e-236 753.0
EH1_k127_6076648_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001371 251.0
EH1_k127_6076648_2 Protein of unknown function (DUF1648) - - - 0.00000000000000000000000000000000000000000000000000000000002526 214.0
EH1_k127_6076648_3 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000000000000001121 190.0
EH1_k127_6076648_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00009384 47.0
EH1_k127_6079194_0 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 349.0
EH1_k127_6079194_1 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002188 286.0
EH1_k127_6079194_2 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000174 93.0
EH1_k127_6079194_3 Putative zinc ribbon domain - - - 0.000000000000000002427 89.0
EH1_k127_6386155_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 579.0
EH1_k127_6386155_1 Rhodanese-like domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 476.0
EH1_k127_6386155_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000005366 158.0
EH1_k127_6396332_0 Ferrous iron transport B domain protein K04759 - - 1.384e-204 654.0
EH1_k127_6396332_1 Helix-hairpin-helix domain K02347 - - 3.27e-200 639.0
EH1_k127_6396332_10 iron dependent repressor K03709,K04758 - - 0.000000000000000000000000000000008808 135.0
EH1_k127_6396332_11 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000009313 134.0
EH1_k127_6396332_12 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000006257 123.0
EH1_k127_6396332_13 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000002161 117.0
EH1_k127_6396332_14 PFAM ABC-2 type transporter K01992 - - 0.000000000000000002819 88.0
EH1_k127_6396332_15 PFAM ABC-2 type transporter K01992 - - 0.000000000002038 68.0
EH1_k127_6396332_2 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 391.0
EH1_k127_6396332_3 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 309.0
EH1_k127_6396332_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 322.0
EH1_k127_6396332_5 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 291.0
EH1_k127_6396332_6 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000003059 252.0
EH1_k127_6396332_7 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
EH1_k127_6396332_8 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000004683 204.0
EH1_k127_6396332_9 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000007236 187.0
EH1_k127_6482958_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008349 593.0
EH1_k127_6482958_1 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 586.0
EH1_k127_6482958_10 - - - - 0.00000000000000000000000000007631 118.0
EH1_k127_6482958_2 PFAM glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 562.0
EH1_k127_6482958_3 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 447.0
EH1_k127_6482958_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 435.0
EH1_k127_6482958_5 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 328.0
EH1_k127_6482958_6 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000001771 180.0
EH1_k127_6482958_7 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000008689 164.0
EH1_k127_6482958_8 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000004699 154.0
EH1_k127_6482958_9 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000216 131.0
EH1_k127_6487758_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1104.0
EH1_k127_6487758_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.932e-220 701.0
EH1_k127_6487758_2 PFAM molybdopterin biosynthesis MoaE K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.00000000000000000000000000000000006604 137.0
EH1_k127_6487758_3 Molybdopterin converting factor, small subunit K03636 - - 0.000003214 49.0
EH1_k127_6491401_0 PFAM SufBD protein K07033 - - 7.613e-211 659.0
EH1_k127_6491401_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 305.0
EH1_k127_6491401_2 PFAM cyclase family protein K07130 - 3.5.1.9 0.00000000000000000000000005523 111.0
EH1_k127_6540902_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 605.0
EH1_k127_6540902_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 481.0
EH1_k127_6540902_2 - - - - 0.00000000000000000000000000003552 119.0
EH1_k127_6540902_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000001823 96.0
EH1_k127_6567278_0 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 482.0
EH1_k127_6567278_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 464.0
EH1_k127_6567278_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 312.0
EH1_k127_6567278_3 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 287.0
EH1_k127_6567278_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000008096 258.0
EH1_k127_6567278_5 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
EH1_k127_6567278_6 transcription factor (CBF NF-Y) - - - 0.00000000000000000000000000697 113.0
EH1_k127_6720274_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1124.0
EH1_k127_6720274_1 Required for chromosome condensation and partitioning K03529 - - 1e-323 1022.0
EH1_k127_6720274_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 336.0
EH1_k127_6720274_11 TIGRFAM F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 326.0
EH1_k127_6720274_12 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 308.0
EH1_k127_6720274_13 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000007799 264.0
EH1_k127_6720274_14 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000000000000000000006747 235.0
EH1_k127_6720274_15 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000003722 210.0
EH1_k127_6720274_16 - - - - 0.0000000000000000000000000000000000000000000000000000000004093 206.0
EH1_k127_6720274_17 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000008659 168.0
EH1_k127_6720274_18 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000002525 152.0
EH1_k127_6720274_19 - - - - 0.00000000000000000000001109 111.0
EH1_k127_6720274_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 4.179e-249 778.0
EH1_k127_6720274_20 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000433 98.0
EH1_k127_6720274_21 Archaeal Nre, N-terminal - - - 0.000000000000000003229 85.0
EH1_k127_6720274_22 - - - - 0.000000000000000005592 89.0
EH1_k127_6720274_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 7.992e-215 674.0
EH1_k127_6720274_4 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 465.0
EH1_k127_6720274_5 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 450.0
EH1_k127_6720274_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 416.0
EH1_k127_6720274_7 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 417.0
EH1_k127_6720274_8 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 390.0
EH1_k127_6720274_9 PFAM major facilitator superfamily MFS_1 K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 394.0
EH1_k127_6827466_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 421.0
EH1_k127_6827466_1 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 347.0
EH1_k127_6827466_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 343.0
EH1_k127_6827466_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 317.0
EH1_k127_6827466_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 303.0
EH1_k127_6827466_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000000008793 199.0
EH1_k127_6827466_6 Flavodoxin - - - 0.000000000000000000000000000000000000000001208 162.0
EH1_k127_6827466_7 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000005843 154.0
EH1_k127_6827466_8 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000001945 142.0
EH1_k127_6827466_9 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000001559 137.0
EH1_k127_6896015_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 402.0
EH1_k127_6896015_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 338.0
EH1_k127_6896015_10 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000608 67.0
EH1_k127_6896015_11 membrane protein (DUF2178) - - - 0.00000000007262 69.0
EH1_k127_6896015_12 Class III signal peptide - - - 0.0000002704 56.0
EH1_k127_6896015_13 DnaJ C terminal domain K03686 - - 0.0009869 44.0
EH1_k127_6896015_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007485 280.0
EH1_k127_6896015_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 257.0
EH1_k127_6896015_4 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000001135 169.0
EH1_k127_6896015_7 PFAM helix-turn-helix domain protein K07729 - - 0.000000000000000000008567 94.0
EH1_k127_6896015_8 PFAM helix-turn-helix domain protein K07729 - - 0.000000000000000001257 87.0
EH1_k127_6896015_9 Transglutaminase-like superfamily - - - 0.000000000000000008735 89.0
EH1_k127_7029835_0 Collagenase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 440.0
EH1_k127_7029835_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003925 280.0
EH1_k127_7078486_0 DEAD DEAH box helicase domain protein K10896 - - 3.52e-301 941.0
EH1_k127_7078486_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 5.329e-262 821.0
EH1_k127_7078486_10 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000001476 231.0
EH1_k127_7078486_11 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000003603 211.0
EH1_k127_7078486_12 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000001771 198.0
EH1_k127_7078486_13 TfuA-like protein - - - 0.000000000000000000000000000000000000000000000121 177.0
EH1_k127_7078486_14 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000009161 170.0
EH1_k127_7078486_15 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000000000000000000223 141.0
EH1_k127_7078486_16 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000000000000000001528 104.0
EH1_k127_7078486_17 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000001142 80.0
EH1_k127_7078486_2 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 610.0
EH1_k127_7078486_3 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 549.0
EH1_k127_7078486_4 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 505.0
EH1_k127_7078486_5 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 504.0
EH1_k127_7078486_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 295.0
EH1_k127_7078486_7 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 287.0
EH1_k127_7078486_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006456 280.0
EH1_k127_7078486_9 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000001183 256.0
EH1_k127_7154646_0 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001798 244.0
EH1_k127_7154646_1 PFAM Tetratricopeptide - - - 0.00000000000006756 78.0
EH1_k127_7154646_2 PBS lyase HEAT-like repeat K22221 - - 0.00000009817 57.0
EH1_k127_72958_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 582.0
EH1_k127_72958_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 326.0
EH1_k127_72958_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
EH1_k127_72958_3 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009293 249.0
EH1_k127_72958_4 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000001862 192.0
EH1_k127_72958_5 protein conserved in archaea K09746 - - 0.0000000000000369 72.0
EH1_k127_7449865_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1283.0
EH1_k127_7449865_1 Transport of potassium into the cell K03549 - - 5.054e-261 816.0
EH1_k127_7449865_10 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 359.0
EH1_k127_7449865_11 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 338.0
EH1_k127_7449865_12 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 316.0
EH1_k127_7449865_13 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 301.0
EH1_k127_7449865_14 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001583 278.0
EH1_k127_7449865_15 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001619 259.0
EH1_k127_7449865_16 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001153 254.0
EH1_k127_7449865_17 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
EH1_k127_7449865_18 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000006823 213.0
EH1_k127_7449865_19 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000001355 205.0
EH1_k127_7449865_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.054e-234 733.0
EH1_k127_7449865_20 PFAM regulatory protein, ArsR K07721 - - 0.0000000000000000000000000000000000000000000000000000005097 199.0
EH1_k127_7449865_21 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.00000000000000000000000000000000000000000000000004079 185.0
EH1_k127_7449865_22 binds to the 23S rRNA K02921 - - 0.000000000000000000000000000000000000000000141 160.0
EH1_k127_7449865_23 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000000000000916 150.0
EH1_k127_7449865_24 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000009123 138.0
EH1_k127_7449865_25 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0000000000000000000000000000000006872 136.0
EH1_k127_7449865_26 HEAT repeats - - - 0.00000000000000000000000001162 115.0
EH1_k127_7449865_27 ATP synthase subunit C K02124 - - 0.00000000000000000000001842 101.0
EH1_k127_7449865_28 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000002383 90.0
EH1_k127_7449865_29 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000002951 79.0
EH1_k127_7449865_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.718e-230 720.0
EH1_k127_7449865_30 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000003762 77.0
EH1_k127_7449865_31 PBS lyase HEAT-like repeat - - - 0.0000000007154 66.0
EH1_k127_7449865_32 - - - - 0.000000002484 59.0
EH1_k127_7449865_33 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.000002842 56.0
EH1_k127_7449865_34 COG0464 ATPases of the AAA class K13525 - - 0.00001842 55.0
EH1_k127_7449865_4 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 610.0
EH1_k127_7449865_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 567.0
EH1_k127_7449865_6 TGS domain protein K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 560.0
EH1_k127_7449865_7 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 456.0
EH1_k127_7449865_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 391.0
EH1_k127_7449865_9 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 394.0
EH1_k127_7490714_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.266e-244 760.0
EH1_k127_7490714_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.71e-237 744.0
EH1_k127_7490714_10 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 338.0
EH1_k127_7490714_11 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
EH1_k127_7490714_12 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000001406 234.0
EH1_k127_7490714_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000115 228.0
EH1_k127_7490714_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000008761 217.0
EH1_k127_7490714_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000004732 208.0
EH1_k127_7490714_16 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000005535 190.0
EH1_k127_7490714_17 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000000000000000004262 166.0
EH1_k127_7490714_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000002023 126.0
EH1_k127_7490714_19 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000002218 91.0
EH1_k127_7490714_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 561.0
EH1_k127_7490714_20 - - - - 0.0000000000003255 69.0
EH1_k127_7490714_3 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 481.0
EH1_k127_7490714_4 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 454.0
EH1_k127_7490714_5 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 448.0
EH1_k127_7490714_6 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 406.0
EH1_k127_7490714_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 398.0
EH1_k127_7490714_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 385.0
EH1_k127_7490714_9 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 368.0
EH1_k127_75090_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 3.891e-234 730.0
EH1_k127_75090_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 539.0
EH1_k127_75090_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 502.0
EH1_k127_75090_3 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 490.0
EH1_k127_7539854_0 PFAM ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 364.0
EH1_k127_7539854_1 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 311.0
EH1_k127_7539854_2 PFAM SufBD protein K07033 - - 0.00000000000000000000000000000000000000000000000000000108 200.0
EH1_k127_7676770_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 6.585e-298 920.0
EH1_k127_7676770_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 534.0
EH1_k127_7676770_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001255 254.0
EH1_k127_7676770_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.00000000000000000000000000000000000000000000001207 175.0
EH1_k127_7730277_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1553.0
EH1_k127_7730277_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1212.0
EH1_k127_7730277_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 581.0
EH1_k127_7730277_11 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 537.0
EH1_k127_7730277_12 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 512.0
EH1_k127_7730277_13 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 477.0
EH1_k127_7730277_14 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 425.0
EH1_k127_7730277_15 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 413.0
EH1_k127_7730277_16 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 402.0
EH1_k127_7730277_17 TIGRFAM cell division ATPase MinD K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 382.0
EH1_k127_7730277_18 Translation initiation factor 2 alpha subunit K03237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 357.0
EH1_k127_7730277_19 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 335.0
EH1_k127_7730277_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0 1043.0
EH1_k127_7730277_20 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 328.0
EH1_k127_7730277_21 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 310.0
EH1_k127_7730277_22 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 313.0
EH1_k127_7730277_23 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 296.0
EH1_k127_7730277_24 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009692 285.0
EH1_k127_7730277_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002312 278.0
EH1_k127_7730277_26 transcription termination protein NusA K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000003344 233.0
EH1_k127_7730277_27 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000001835 224.0
EH1_k127_7730277_28 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000003624 215.0
EH1_k127_7730277_29 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000000000000000000001656 201.0
EH1_k127_7730277_3 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 9.495e-300 923.0
EH1_k127_7730277_30 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000000006846 169.0
EH1_k127_7730277_31 - - - - 0.0000000000000000000000000000000000000000001485 164.0
EH1_k127_7730277_32 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000001159 162.0
EH1_k127_7730277_33 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000000000003885 154.0
EH1_k127_7730277_34 Stage II sporulation protein M K06384 - - 0.000000000000000000000000000000000003416 144.0
EH1_k127_7730277_35 protein conserved in archaea K09723 - - 0.0000000000000000000000000000000000831 142.0
EH1_k127_7730277_36 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000000000000000001242 126.0
EH1_k127_7730277_37 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000000000001047 124.0
EH1_k127_7730277_38 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000009213 123.0
EH1_k127_7730277_39 metal-binding protein - - - 0.00000000000000000000000006648 109.0
EH1_k127_7730277_4 Conserved region in glutamate synthase - - - 6.876e-289 892.0
EH1_k127_7730277_40 PFAM Ribosomal protein S27E K02978 - - 0.000000000000000000000001448 103.0
EH1_k127_7730277_41 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.0000000000000000000002879 98.0
EH1_k127_7730277_42 Tetratricopeptide repeat K12600 - - 0.000000000000000004115 93.0
EH1_k127_7730277_43 - - - - 0.000000000000000004176 92.0
EH1_k127_7730277_44 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000008043 84.0
EH1_k127_7730277_45 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000006027 73.0
EH1_k127_7730277_46 TIR domain - - - 0.00000000000461 73.0
EH1_k127_7730277_47 Roadblock LC7 family protein K06945,K07131 - - 0.000000000004664 71.0
EH1_k127_7730277_48 cellular component assembly - - - 0.000000000926 60.0
EH1_k127_7730277_49 - - - - 0.000000006403 64.0
EH1_k127_7730277_5 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 1.819e-229 720.0
EH1_k127_7730277_50 - - - - 0.0000002101 55.0
EH1_k127_7730277_51 - - - - 0.000006097 50.0
EH1_k127_7730277_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 2.167e-221 694.0
EH1_k127_7730277_7 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 611.0
EH1_k127_7730277_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 596.0
EH1_k127_7730277_9 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 580.0
EH1_k127_7747564_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1258.0
EH1_k127_7747564_1 PFAM CBS domain - - - 1.778e-234 734.0
EH1_k127_7747564_10 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003067 251.0
EH1_k127_7747564_11 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000007906 244.0
EH1_k127_7747564_12 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000001595 233.0
EH1_k127_7747564_13 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000003716 234.0
EH1_k127_7747564_14 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000000000000000000000005772 224.0
EH1_k127_7747564_15 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000000000000004667 222.0
EH1_k127_7747564_16 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
EH1_k127_7747564_17 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.00000000000000000000000000000000000000000000000000000000000001487 219.0
EH1_k127_7747564_18 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.000000000000000000000000000000000000000000000000001484 185.0
EH1_k127_7747564_19 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.0000000000000000000000000000000000000000000000001835 181.0
EH1_k127_7747564_2 Proton-conducting membrane transporter K05568 - - 1.813e-211 668.0
EH1_k127_7747564_20 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000002 170.0
EH1_k127_7747564_21 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000001952 164.0
EH1_k127_7747564_22 - - - - 0.000000000000000000000000000000000000008534 150.0
EH1_k127_7747564_23 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000000000000000000007491 140.0
EH1_k127_7747564_24 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000001091 127.0
EH1_k127_7747564_25 zinc finger, SWIM - - - 0.000000000000000000000000000002587 123.0
EH1_k127_7747564_26 - - - - 0.000000000000000000000000002976 116.0
EH1_k127_7747564_27 Domain of unknown function (DUF4040) - - - 0.0000000000000000000002097 99.0
EH1_k127_7747564_28 Membrane bound hydrogenase - - - 0.0000000000000000000004137 98.0
EH1_k127_7747564_29 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000008018 104.0
EH1_k127_7747564_3 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 4.688e-196 617.0
EH1_k127_7747564_30 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000000003474 92.0
EH1_k127_7747564_31 - - - - 0.00000000000004208 78.0
EH1_k127_7747564_32 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000479 67.0
EH1_k127_7747564_33 - - - - 0.0000000002149 65.0
EH1_k127_7747564_4 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 6.062e-196 621.0
EH1_k127_7747564_5 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 427.0
EH1_k127_7747564_6 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 381.0
EH1_k127_7747564_7 RNA methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 355.0
EH1_k127_7747564_8 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
EH1_k127_7747564_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 260.0
EH1_k127_7874106_0 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
EH1_k127_7874106_1 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000003748 234.0
EH1_k127_7874106_2 - - - - 0.00000000000000000000000000000000000000000000000000005269 205.0
EH1_k127_7874106_3 PFAM PQ loop repeat K15383 - - 0.00000000000000000008989 91.0
EH1_k127_7874106_4 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000001377 83.0
EH1_k127_7980318_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1196.0
EH1_k127_7980318_1 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 458.0
EH1_k127_7980318_2 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.00000000000000000000000000000000000000000000000000396 186.0
EH1_k127_8065733_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 408.0
EH1_k127_8065733_1 - - - - 0.0000000000000000000000000000008734 127.0
EH1_k127_8065733_2 - - - - 0.0000000000000001049 82.0
EH1_k127_8107799_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.0 1176.0
EH1_k127_8107799_1 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 5.677e-197 616.0
EH1_k127_8107799_10 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.000006353 50.0
EH1_k127_8107799_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 382.0
EH1_k127_8107799_3 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 377.0
EH1_k127_8107799_4 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 342.0
EH1_k127_8107799_5 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 314.0
EH1_k127_8107799_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
EH1_k127_8107799_7 - - - - 0.00000000000000000000000000000000000000000000001037 179.0
EH1_k127_8107799_8 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000000000009621 151.0
EH1_k127_8107799_9 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000989 89.0
EH1_k127_8109_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 411.0
EH1_k127_8109_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 373.0
EH1_k127_8109_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 370.0
EH1_k127_8109_3 Domain of unknown function (DUF1917) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 288.0
EH1_k127_8109_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000001403 240.0
EH1_k127_8109_5 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000001196 85.0
EH1_k127_8207038_0 Involved in protein export K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 313.0
EH1_k127_8207038_1 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007494 264.0
EH1_k127_8207038_2 Protein of unknown function (DUF2551) - - - 0.000000000000000000000000000000000009123 138.0
EH1_k127_8207038_3 - - - - 0.0000000000001695 73.0
EH1_k127_8281675_0 Protein of unknown function (DUF460) K09150 - - 2.191e-231 733.0
EH1_k127_8281675_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 2.703e-199 623.0
EH1_k127_8281675_10 - - - - 0.000000000000000000000000000000000000000002408 162.0
EH1_k127_8281675_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000000000000000000000002158 129.0
EH1_k127_8281675_12 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000001358 92.0
EH1_k127_8281675_2 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 359.0
EH1_k127_8281675_3 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 348.0
EH1_k127_8281675_4 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 348.0
EH1_k127_8281675_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 317.0
EH1_k127_8281675_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 308.0
EH1_k127_8281675_7 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 286.0
EH1_k127_8281675_8 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 274.0
EH1_k127_8281675_9 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000000000000000000000000434 175.0