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Overview

ID MAG01004
Name EH1_bin.26
Sample SMP0028
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family Methanospirillaceae
Genus UBA9949
Species
Assembly information
Completeness (%) 55.39
Contamination (%) 0.0
GC content (%) 55.0
N50 (bp) 4,408
Genome size (bp) 696,536

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes843

Gene name Description KEGG GOs EC E-value Score Sequence
EH1_k127_104819_0 KH, type 1, domain K07041 - - 0.0 1022.0
EH1_k127_104819_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 300.0
EH1_k127_104819_2 ATPases associated with a variety of cellular activities K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 292.0
EH1_k127_104819_3 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 289.0
EH1_k127_1070081_0 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 535.0
EH1_k127_1070081_1 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 426.0
EH1_k127_1070081_2 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000001797 170.0
EH1_k127_1070081_3 - - - - 0.000000000000000000000000000000000000000001445 164.0
EH1_k127_1070081_4 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000001144 135.0
EH1_k127_1070081_5 PFAM regulatory protein, ArsR K21903 - - 0.00000000000000000000000003022 113.0
EH1_k127_1079563_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.949e-208 654.0
EH1_k127_1079563_1 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 389.0
EH1_k127_1079563_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000003779 240.0
EH1_k127_1079563_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000001086 226.0
EH1_k127_1079563_4 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000002087 203.0
EH1_k127_1079563_5 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000003078 201.0
EH1_k127_1079563_6 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000005548 167.0
EH1_k127_1079563_7 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000000007213 134.0
EH1_k127_1079563_8 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000002701 113.0
EH1_k127_1079563_9 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000002077 111.0
EH1_k127_1109154_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 526.0
EH1_k127_1109154_1 4-Hydroxyphenylpyruvate dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 321.0
EH1_k127_1109154_2 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000008872 234.0
EH1_k127_1137170_0 Uncharacterized membrane protein (DUF2298) - - - 4.693e-219 700.0
EH1_k127_1137170_1 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002112 246.0
EH1_k127_1139157_0 Met-10+ like-protein K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000002022 268.0
EH1_k127_1139157_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000009851 202.0
EH1_k127_1139157_2 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000000002283 181.0
EH1_k127_1139157_3 PFAM Uncharacterised protein family UPF0114 - - - 0.000000000000000000000000371 111.0
EH1_k127_1139157_4 - - - - 0.0000000000000005151 89.0
EH1_k127_1139995_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1177.0
EH1_k127_1139995_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1113.0
EH1_k127_1139995_2 - - - - 0.00000000004526 63.0
EH1_k127_1164123_0 LOR SDH bifunctional enzyme conserved - - - 1.807e-197 623.0
EH1_k127_1164123_1 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 411.0
EH1_k127_1164123_2 - - - - 0.00000000000000000000000000000000000000000000000000000000001893 220.0
EH1_k127_1164123_3 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.000000000000000000000000000000000000007665 148.0
EH1_k127_1189742_0 Replication factor C K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 355.0
EH1_k127_1189742_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 314.0
EH1_k127_1189742_2 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000004712 241.0
EH1_k127_1189742_3 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000004406 132.0
EH1_k127_1189742_4 PFAM AIR synthase related protein K07388 - - 0.0000000000000000000000000000009574 124.0
EH1_k127_1230337_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.583e-308 957.0
EH1_k127_1230337_1 PFAM Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 570.0
EH1_k127_1230337_2 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000001591 206.0
EH1_k127_1230337_3 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000001497 85.0
EH1_k127_125252_0 ATP-grasp domain K06914 - 6.3.4.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 408.0
EH1_k127_125252_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 402.0
EH1_k127_125252_2 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000003702 264.0
EH1_k127_125252_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000008978 122.0
EH1_k127_125601_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 9.344e-197 627.0
EH1_k127_125601_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
EH1_k127_125601_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 591.0
EH1_k127_125601_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 385.0
EH1_k127_125601_4 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001612 246.0
EH1_k127_125601_5 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000005591 199.0
EH1_k127_125601_6 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000002064 109.0
EH1_k127_125601_7 PFAM Uncharacterised conserved protein UCP006577 - - - 0.0000000000000000916 83.0
EH1_k127_125601_8 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000003088 69.0
EH1_k127_1306317_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 578.0
EH1_k127_1306317_1 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 315.0
EH1_k127_1306317_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000006082 101.0
EH1_k127_1306317_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000002484 78.0
EH1_k127_1365367_0 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000000000000000000001074 208.0
EH1_k127_1365367_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000004318 169.0
EH1_k127_1365367_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000002371 69.0
EH1_k127_1365367_3 Mechanosensitive ion channel - - - 0.00000002972 57.0
EH1_k127_1422654_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 539.0
EH1_k127_1422654_1 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000000000001218 175.0
EH1_k127_1422654_2 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000003101 157.0
EH1_k127_1542696_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 580.0
EH1_k127_1542696_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001229 268.0
EH1_k127_1542696_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000005391 126.0
EH1_k127_1542696_3 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0000000004574 61.0
EH1_k127_1604082_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 582.0
EH1_k127_1604082_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 475.0
EH1_k127_1604082_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 367.0
EH1_k127_1604082_3 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000006107 269.0
EH1_k127_1604082_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
EH1_k127_1604082_5 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000146 229.0
EH1_k127_1604082_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000004717 171.0
EH1_k127_161088_0 PFAM PilT protein domain protein K06865 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 443.0
EH1_k127_161088_1 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000000000000000000000000000000000000000000000000000000000000000000004779 247.0
EH1_k127_161088_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000009868 187.0
EH1_k127_1660334_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 558.0
EH1_k127_1660334_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 313.0
EH1_k127_1660334_2 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 284.0
EH1_k127_1660334_3 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000003997 105.0
EH1_k127_1660334_4 Cysteine-rich small domain K08260 - 3.5.1.90 0.00000000000000000000001926 100.0
EH1_k127_1660334_5 Ferredoxin K05337 - - 0.0000000000000000005606 88.0
EH1_k127_1660334_6 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000001614 76.0
EH1_k127_1770381_0 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 419.0
EH1_k127_1770381_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000001446 181.0
EH1_k127_1770381_2 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000004995 176.0
EH1_k127_1770381_3 - - - - 0.00000000000000000000003485 109.0
EH1_k127_1770381_4 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000005434 94.0
EH1_k127_177889_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003356 286.0
EH1_k127_177889_1 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000002757 218.0
EH1_k127_177889_2 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000002465 120.0
EH1_k127_177889_3 DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000007374 64.0
EH1_k127_1857225_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1019.0
EH1_k127_1857225_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 550.0
EH1_k127_1857225_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000001255 183.0
EH1_k127_1857225_3 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.0000000000000000000000001584 109.0
EH1_k127_1910161_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 606.0
EH1_k127_1910161_1 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 561.0
EH1_k127_1910161_10 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000000000000001344 172.0
EH1_k127_1910161_11 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000002183 162.0
EH1_k127_1910161_2 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 542.0
EH1_k127_1910161_3 Dihydrouridine synthase (Dus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 532.0
EH1_k127_1910161_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 486.0
EH1_k127_1910161_5 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 471.0
EH1_k127_1910161_6 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 397.0
EH1_k127_1910161_7 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 371.0
EH1_k127_1910161_8 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000003051 221.0
EH1_k127_1910161_9 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.0000000000000000000000000000000000000000000000000000000003505 204.0
EH1_k127_199714_0 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 425.0
EH1_k127_199714_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 363.0
EH1_k127_199714_2 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000000000000000000000009766 237.0
EH1_k127_199714_3 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000009973 224.0
EH1_k127_199714_4 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
EH1_k127_199714_5 TPR repeat-containing protein - - - 0.0000000000000000001049 97.0
EH1_k127_210793_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1267.0
EH1_k127_210793_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
EH1_k127_210793_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000007027 197.0
EH1_k127_213722_0 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 589.0
EH1_k127_213722_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 536.0
EH1_k127_213722_2 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001359 271.0
EH1_k127_213722_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000001779 234.0
EH1_k127_2138908_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.673e-270 838.0
EH1_k127_2138908_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 588.0
EH1_k127_2138908_2 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 566.0
EH1_k127_2138908_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 501.0
EH1_k127_2138908_4 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 427.0
EH1_k127_2138908_5 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 424.0
EH1_k127_2138908_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 259.0
EH1_k127_2138908_7 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000005222 159.0
EH1_k127_2138908_8 - - - - 0.000000000000000000000006686 103.0
EH1_k127_2138908_9 PFAM PKD domain containing protein - - - 0.000000000000000001797 94.0
EH1_k127_2172258_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 605.0
EH1_k127_2172258_1 PFAM PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000003453 140.0
EH1_k127_2172258_2 Transcriptional regulator K07108 - - 0.0000000000000000000000000000002062 126.0
EH1_k127_2172258_3 transcriptional regulators K03724 - - 0.0000000000000000000000000002538 115.0
EH1_k127_2172258_4 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000044 106.0
EH1_k127_2172258_5 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.00000000000000001574 89.0
EH1_k127_2185908_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 2.188e-235 734.0
EH1_k127_2185908_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.766e-227 709.0
EH1_k127_2185908_2 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 600.0
EH1_k127_2185908_3 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 570.0
EH1_k127_2185908_4 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 412.0
EH1_k127_2185908_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003915 286.0
EH1_k127_2185908_6 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
EH1_k127_2185908_7 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000002395 158.0
EH1_k127_2185908_8 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000001855 107.0
EH1_k127_2189606_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.151e-266 823.0
EH1_k127_2189606_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.202e-213 663.0
EH1_k127_2207871_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1089.0
EH1_k127_2207871_1 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004 267.0
EH1_k127_2207871_2 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000004856 263.0
EH1_k127_2207871_3 PFAM thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000006414 252.0
EH1_k127_2289478_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 7.588e-213 672.0
EH1_k127_2289478_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 1.718e-202 645.0
EH1_k127_2289478_2 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000003172 195.0
EH1_k127_2289478_3 PFAM alanine dehydrogenase PNT domain protein K00259,K00324 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1,1.6.1.2 0.0000003704 53.0
EH1_k127_2296779_0 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 3.598e-259 804.0
EH1_k127_2296779_1 PFAM Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000001331 234.0
EH1_k127_2296779_2 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000008251 190.0
EH1_k127_2296779_3 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.00000000000000000000000004553 109.0
EH1_k127_2296779_4 - - - - 0.000000009679 57.0
EH1_k127_2328792_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 4.498e-200 634.0
EH1_k127_2328792_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 580.0
EH1_k127_2328792_2 - - - - 0.00000000000000000000000001655 111.0
EH1_k127_2328792_3 - - - - 0.000000000000000000107 92.0
EH1_k127_2374041_0 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 507.0
EH1_k127_2374041_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 439.0
EH1_k127_2374041_2 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 370.0
EH1_k127_2374041_3 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000943 267.0
EH1_k127_2484490_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 1.563e-206 651.0
EH1_k127_2484490_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 342.0
EH1_k127_2484490_2 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 315.0
EH1_k127_2484490_3 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000005226 220.0
EH1_k127_2484490_4 Domain of unknown function (DUF1805) - - - 0.0000000000000000000000000000002231 125.0
EH1_k127_2484490_5 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000004048 69.0
EH1_k127_2502176_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 2.274e-227 715.0
EH1_k127_2502176_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 526.0
EH1_k127_2502176_10 metal-binding protein - - - 0.000000000000000000000000000002578 122.0
EH1_k127_2502176_11 PFAM Ribosomal protein S27E K02978 - - 0.000000000000000000000123 98.0
EH1_k127_2502176_12 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000000168 76.0
EH1_k127_2502176_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 448.0
EH1_k127_2502176_3 PHP C-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 441.0
EH1_k127_2502176_4 Translation initiation factor 2 alpha subunit K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 370.0
EH1_k127_2502176_5 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 321.0
EH1_k127_2502176_6 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 289.0
EH1_k127_2502176_7 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000000000000000000000000009856 216.0
EH1_k127_2502176_8 protein conserved in archaea K09723 - - 0.00000000000000000000000000000000000000000000000000002126 196.0
EH1_k127_2502176_9 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000000000000002306 185.0
EH1_k127_258857_0 permease K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
EH1_k127_258857_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000009087 180.0
EH1_k127_258857_2 signal-transduction protein containing cAMP-binding and CBS domains K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.0000000000000000000000000000000001913 137.0
EH1_k127_258857_3 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000008135 66.0
EH1_k127_2592336_0 helicase activity K06915,K19172 - - 2.235e-196 622.0
EH1_k127_2592336_1 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000001168 198.0
EH1_k127_2592336_2 Flavodoxin - - - 0.000000000000000000000000000002842 126.0
EH1_k127_2592336_3 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000004145 126.0
EH1_k127_2592336_4 Short repeat of unknown function (DUF308) - - - 0.000000000000000000001089 100.0
EH1_k127_2592336_5 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0006574 46.0
EH1_k127_2671685_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 594.0
EH1_k127_2671685_1 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 553.0
EH1_k127_2671685_2 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000007645 184.0
EH1_k127_2671685_3 helicase activity K06915 - - 0.0000000000000000000000005683 110.0
EH1_k127_2677730_0 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 416.0
EH1_k127_2677730_1 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001375 257.0
EH1_k127_2677730_2 PFAM Cation K03498 - - 0.000000000000000000000000000003483 123.0
EH1_k127_2677730_3 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000002236 72.0
EH1_k127_2677730_4 PFAM Cation K03498 - - 0.000000000004981 74.0
EH1_k127_2751177_0 Helix-hairpin-helix domain K02347 - - 3.802e-199 634.0
EH1_k127_2751177_1 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 380.0
EH1_k127_2751177_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 329.0
EH1_k127_2751177_3 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000006162 240.0
EH1_k127_2808687_0 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 269.0
EH1_k127_2808687_1 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000009206 233.0
EH1_k127_2808687_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000004549 213.0
EH1_k127_2808687_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000003503 184.0
EH1_k127_2808687_4 Small multi-drug export protein - - - 0.00000000000000000000000000000000000000005225 160.0
EH1_k127_28276_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 474.0
EH1_k127_28276_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 433.0
EH1_k127_28276_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000009605 220.0
EH1_k127_28276_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000502 217.0
EH1_k127_28276_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000003111 207.0
EH1_k127_28276_13 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000000000000000000002114 177.0
EH1_k127_28276_14 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000000000000000000000000000001576 167.0
EH1_k127_28276_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000000000000003322 124.0
EH1_k127_28276_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000904 56.0
EH1_k127_28276_17 COG3364 Zn-ribbon containing protein K07163 - - 0.0000006466 52.0
EH1_k127_28276_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 373.0
EH1_k127_28276_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 366.0
EH1_k127_28276_4 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 347.0
EH1_k127_28276_5 PFAM GTP-binding protein HSR1-related K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 344.0
EH1_k127_28276_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005064 273.0
EH1_k127_28276_7 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001171 264.0
EH1_k127_28276_8 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000031 258.0
EH1_k127_28276_9 Located on the platform of the 30S subunit K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006044 244.0
EH1_k127_2843836_0 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001645 274.0
EH1_k127_2843836_1 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000008568 166.0
EH1_k127_2843836_2 - - - - 0.00000000000000000000000000000000003865 138.0
EH1_k127_2843836_3 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000006816 87.0
EH1_k127_2878305_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.365e-241 758.0
EH1_k127_2878305_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 6.06e-224 699.0
EH1_k127_2878305_2 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000004038 201.0
EH1_k127_2878305_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000003684 115.0
EH1_k127_288641_0 DEAD DEAH box helicase domain protein K10896 - - 5.053e-300 936.0
EH1_k127_288641_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000002816 191.0
EH1_k127_288641_2 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000000000000000000002596 153.0
EH1_k127_288641_3 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.00000000000000000000000000001697 118.0
EH1_k127_288641_4 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000000000000000000009097 116.0
EH1_k127_2940500_0 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000002204 266.0
EH1_k127_2940500_1 PFAM Radical SAM domain protein K02585 - - 0.00000000000000000000000000000000000000001934 153.0
EH1_k127_2940500_2 - - - - 0.00000000000000000000000000000000001959 137.0
EH1_k127_2940500_3 - - - - 0.000000000000000703 83.0
EH1_k127_2940500_4 - - - - 0.000000000000006045 76.0
EH1_k127_3193256_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 586.0
EH1_k127_3193256_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 580.0
EH1_k127_320841_0 - - - - 0.0000000000000000000000000000000000000000000001066 184.0
EH1_k127_320841_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000001829 164.0
EH1_k127_3211170_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 3.465e-317 981.0
EH1_k127_3211170_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 346.0
EH1_k127_3211170_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 344.0
EH1_k127_3211170_3 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003413 279.0
EH1_k127_3211170_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002279 272.0
EH1_k127_3211170_5 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000001316 236.0
EH1_k127_3211170_6 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000000000000000000000001152 174.0
EH1_k127_3217649_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 381.0
EH1_k127_3217649_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 289.0
EH1_k127_3217649_2 - - - - 0.000000000000000000000000000000000000000005022 162.0
EH1_k127_3254399_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 607.0
EH1_k127_3254399_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000003545 201.0
EH1_k127_3254399_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000006271 182.0
EH1_k127_325989_0 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 379.0
EH1_k127_325989_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 308.0
EH1_k127_325989_2 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.00000000000000000000000000000000000000000000000000000000000000000003745 236.0
EH1_k127_325989_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000006687 147.0
EH1_k127_325989_4 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.0000000000000000000000000000000000008712 140.0
EH1_k127_325989_5 - - - - 0.000000000008799 69.0
EH1_k127_3263179_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 432.0
EH1_k127_3263179_1 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000004817 240.0
EH1_k127_3284854_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1276.0
EH1_k127_3284854_1 PFAM PilT protein domain protein K06865 - - 0.00000000000000000000000000000000000000000001124 164.0
EH1_k127_3286200_0 TIGRFAM UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 569.0
EH1_k127_3286200_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 536.0
EH1_k127_3286200_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008852 272.0
EH1_k127_3286200_3 - - - - 0.0000000000000000000000000000000000244 141.0
EH1_k127_3286200_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000001421 76.0
EH1_k127_3305238_0 Involved in cell shape control K22222 - - 2.017e-197 621.0
EH1_k127_3305238_1 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 471.0
EH1_k127_3305238_2 - - - - 0.0000000000000000000000000000000000001201 153.0
EH1_k127_3310157_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.025e-207 650.0
EH1_k127_3310157_1 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 436.0
EH1_k127_3310157_2 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 435.0
EH1_k127_3310157_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 362.0
EH1_k127_3310157_4 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000002207 228.0
EH1_k127_3310157_5 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000000000000000001628 92.0
EH1_k127_3310157_6 LOR SDH bifunctional enzyme conserved - - - 0.0000009189 52.0
EH1_k127_332930_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1168.0
EH1_k127_332930_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 331.0
EH1_k127_332930_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 288.0
EH1_k127_332930_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004054 281.0
EH1_k127_332930_4 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000001474 201.0
EH1_k127_332930_5 Ribosomal protein S23 K02973 - - 0.0000000000000000000000000000000001611 136.0
EH1_k127_3451557_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 6.183e-287 883.0
EH1_k127_3451557_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 568.0
EH1_k127_3485981_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 3.695e-214 671.0
EH1_k127_3485981_1 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 479.0
EH1_k127_3485981_2 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 300.0
EH1_k127_3485981_3 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002648 241.0
EH1_k127_3485981_4 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.000000000000000000000000000000000000000000000000000000000000000001806 231.0
EH1_k127_3485981_5 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000000000000001345 215.0
EH1_k127_3485981_6 - - - - 0.0000000002417 68.0
EH1_k127_3552102_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 546.0
EH1_k127_3552102_1 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 370.0
EH1_k127_3552102_10 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.000000000000000002882 90.0
EH1_k127_3552102_11 PFAM molydopterin dinucleotide-binding region K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.000000000001725 71.0
EH1_k127_3552102_12 Predicted membrane protein (DUF2108) K14095 - - 0.000000000005232 70.0
EH1_k127_3552102_13 - K14100 - - 0.000001866 52.0
EH1_k127_3552102_2 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003253 267.0
EH1_k127_3552102_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008347 253.0
EH1_k127_3552102_4 4Fe-4S dicluster domain K11260,K14107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009381 250.0
EH1_k127_3552102_5 Predicted membrane protein (DUF2105) K14098 - - 0.000000000000000000000000000000000000000000000000000000001998 205.0
EH1_k127_3552102_6 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.000000000000000000000000000000000000000000000000002403 186.0
EH1_k127_3552102_7 Predicted membrane protein (DUF2109) K14094 - - 0.000000000000000000000000002578 115.0
EH1_k127_3552102_8 Predicted membrane protein (DUF2107) K14096 - - 0.000000000000000000001051 96.0
EH1_k127_3552102_9 - K14093 - - 0.000000000000000000001094 94.0
EH1_k127_3574301_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 313.0
EH1_k127_3574301_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 281.0
EH1_k127_3574301_2 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003685 271.0
EH1_k127_3574301_3 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000000002532 217.0
EH1_k127_3574301_4 transcription factor (CBF NF-Y) - - - 0.0000000000000000000000000002464 114.0
EH1_k127_3574301_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0002279 49.0
EH1_k127_3600592_0 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007181 268.0
EH1_k127_3600592_1 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000000000000000000000000000000000000003519 231.0
EH1_k127_3600592_2 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000008014 113.0
EH1_k127_3600592_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000009274 67.0
EH1_k127_3627065_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 392.0
EH1_k127_3627065_1 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 374.0
EH1_k127_3627065_2 DEAD DEAH box helicase K03724 - - 0.000000000000000000004871 99.0
EH1_k127_3647367_0 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000009625 183.0
EH1_k127_3647367_1 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000004063 119.0
EH1_k127_3647367_2 TIGR00268 family K06864 - - 0.000000000000000000000000001794 113.0
EH1_k127_3647367_3 membrane transporter protein K07090 - - 0.000000004871 61.0
EH1_k127_3653425_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 400.0
EH1_k127_3653425_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003912 263.0
EH1_k127_3653425_2 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000002693 119.0
EH1_k127_3653425_3 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000008715 65.0
EH1_k127_3663846_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 503.0
EH1_k127_3663846_1 tRNAHis guanylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 299.0
EH1_k127_3663846_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000003589 196.0
EH1_k127_3663846_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000005376 163.0
EH1_k127_3663846_4 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000003022 124.0
EH1_k127_3684515_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 3.951e-231 721.0
EH1_k127_3684515_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 550.0
EH1_k127_3684515_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 468.0
EH1_k127_3684515_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000000000000008253 247.0
EH1_k127_3684515_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000000000000000000004381 173.0
EH1_k127_3684515_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000001654 175.0
EH1_k127_3684515_6 PFAM Ribosomal LX protein K02944 - - 0.000000000000000001726 86.0
EH1_k127_3684515_7 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000308 53.0
EH1_k127_3718000_0 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 312.0
EH1_k127_3718000_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006869 243.0
EH1_k127_3718000_2 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001437 247.0
EH1_k127_3718000_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000000003628 166.0
EH1_k127_3757781_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.016e-194 612.0
EH1_k127_3757781_1 PFAM regulatory protein, ArsR K07721 - - 0.000000000000000000000000000000000000000000000000000000000000005543 222.0
EH1_k127_3757781_2 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000002311 110.0
EH1_k127_4262224_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 1.134e-215 678.0
EH1_k127_4262224_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 8.499e-202 634.0
EH1_k127_4262224_2 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 392.0
EH1_k127_4262224_3 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007971 273.0
EH1_k127_4282265_0 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 433.0
EH1_k127_4282265_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 392.0
EH1_k127_4282265_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 355.0
EH1_k127_4282265_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001296 212.0
EH1_k127_4282265_4 - - - - 0.00000000000000000000000003535 113.0
EH1_k127_4282265_5 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00004165 46.0
EH1_k127_4366567_0 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 357.0
EH1_k127_4366567_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 321.0
EH1_k127_4366567_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 308.0
EH1_k127_4366567_3 Trm112p-like protein - - - 0.00000000000000001616 85.0
EH1_k127_4372432_0 phosphoesterase RecJ domain protein - - - 7.235e-198 629.0
EH1_k127_4372432_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 414.0
EH1_k127_4372432_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000102 274.0
EH1_k127_4372432_3 Ion channel - - - 0.0000000000002325 72.0
EH1_k127_4378239_0 PFAM NAD(P) transhydrogenase, beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 473.0
EH1_k127_4378239_1 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 447.0
EH1_k127_4378239_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 416.0
EH1_k127_4378239_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 367.0
EH1_k127_4378239_4 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 366.0
EH1_k127_4378239_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 270.0
EH1_k127_4378239_6 - - - - 0.000000000000000000000000000000000000000000000000000000000008171 211.0
EH1_k127_4429444_0 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 347.0
EH1_k127_4429444_1 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 296.0
EH1_k127_4429444_2 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000174 225.0
EH1_k127_4429444_3 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000004014 210.0
EH1_k127_4429444_4 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000000000004243 160.0
EH1_k127_4457951_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1126.0
EH1_k127_4457951_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 9.782e-248 790.0
EH1_k127_4457951_10 - K06868 - 2.5.1.73 0.0000000000006958 70.0
EH1_k127_4457951_2 AAA-like domain K06915 - - 4.234e-222 701.0
EH1_k127_4457951_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 544.0
EH1_k127_4457951_4 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 469.0
EH1_k127_4457951_5 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 445.0
EH1_k127_4457951_6 PFAM formate nitrite transporter K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 424.0
EH1_k127_4457951_7 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 370.0
EH1_k127_4457951_8 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 332.0
EH1_k127_4457951_9 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.000000000000000000000000000000000000000000000000000000000002524 213.0
EH1_k127_4464749_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1598.0
EH1_k127_4464749_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 2.145e-199 626.0
EH1_k127_4464749_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 578.0
EH1_k127_4464749_3 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000001014 188.0
EH1_k127_4464749_4 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000000000000000000000000003265 158.0
EH1_k127_4488061_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 9.702e-226 705.0
EH1_k127_4488061_1 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 409.0
EH1_k127_4488061_2 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 354.0
EH1_k127_4491288_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 302.0
EH1_k127_4491288_1 Belongs to the UPF0305 family - - - 0.000000000000000000000000000000000000000000000000000000000000000002774 231.0
EH1_k127_4491288_2 Molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000001375 160.0
EH1_k127_4491288_3 Phosphate-starvation-inducible E - - - 0.000000000000000000000000001412 117.0
EH1_k127_4491288_4 PFAM GCN5-related N-acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.000000000000000000000001731 108.0
EH1_k127_4491288_5 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000003146 91.0
EH1_k127_4547867_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 451.0
EH1_k127_4547867_1 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 445.0
EH1_k127_4547867_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000429 144.0
EH1_k127_4547867_11 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.00000000000000000146 89.0
EH1_k127_4547867_12 PDGLE domain K02009 - - 0.000000000000000002078 96.0
EH1_k127_4547867_13 signal peptide peptidase K04773 - - 0.0005491 44.0
EH1_k127_4547867_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 415.0
EH1_k127_4547867_3 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 364.0
EH1_k127_4547867_4 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
EH1_k127_4547867_5 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 312.0
EH1_k127_4547867_6 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002164 279.0
EH1_k127_4547867_7 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000000000000000000000001461 175.0
EH1_k127_4547867_8 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000002237 163.0
EH1_k127_4547867_9 - - - - 0.00000000000000000000000000000000000000009613 154.0
EH1_k127_4580808_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
EH1_k127_4580808_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000002637 206.0
EH1_k127_4609975_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 479.0
EH1_k127_4609975_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 447.0
EH1_k127_4609975_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 444.0
EH1_k127_4609975_3 Collagenase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 426.0
EH1_k127_4609975_4 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000009319 193.0
EH1_k127_4609975_5 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000001539 98.0
EH1_k127_4708291_0 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 364.0
EH1_k127_4708291_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009262 278.0
EH1_k127_4708291_2 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000002262 229.0
EH1_k127_4708291_3 PFAM Phosphatidylglycerophosphatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000002442 228.0
EH1_k127_4726491_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 391.0
EH1_k127_4726491_1 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 368.0
EH1_k127_4726491_10 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000004411 118.0
EH1_k127_4726491_2 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 361.0
EH1_k127_4726491_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 358.0
EH1_k127_4726491_4 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 315.0
EH1_k127_4726491_5 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000001214 261.0
EH1_k127_4726491_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000143 248.0
EH1_k127_4726491_7 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000005406 210.0
EH1_k127_4726491_8 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.00000000000000000000000000000000000000000000000708 178.0
EH1_k127_4726491_9 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.0000000000000000000000000000001968 136.0
EH1_k127_4872874_0 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 489.0
EH1_k127_4872874_1 iron dependent repressor K03709,K04758 - - 0.00000000000000000000000000000000000000002165 160.0
EH1_k127_5332025_0 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 357.0
EH1_k127_5332025_1 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
EH1_k127_5332025_2 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000539 216.0
EH1_k127_5332025_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000106 166.0
EH1_k127_5332025_4 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000002635 55.0
EH1_k127_5344144_0 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 588.0
EH1_k127_5344144_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 304.0
EH1_k127_5344144_2 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000001935 222.0
EH1_k127_5344144_3 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000000001198 135.0
EH1_k127_5344144_4 Involved in protein export K03074 - - 0.00000006964 54.0
EH1_k127_5344144_5 - - - - 0.000006353 50.0
EH1_k127_5357161_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 372.0
EH1_k127_5388682_0 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 534.0
EH1_k127_5388682_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 375.0
EH1_k127_5388682_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 363.0
EH1_k127_5388682_3 - - - - 0.0000000000000000000000000000000000000000008407 160.0
EH1_k127_5388682_4 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000000000000000295 151.0
EH1_k127_5388682_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000001526 95.0
EH1_k127_5388682_6 Domain of unknown function (DUF373) K08975 - - 0.000002114 51.0
EH1_k127_5393799_0 Protein of unknown function (DUF460) K09150 - - 1.843e-251 793.0
EH1_k127_5393799_1 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 381.0
EH1_k127_5393799_2 Rio2, N-terminal K07179 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 361.0
EH1_k127_5393799_3 PFAM TrkA-N domain protein K10716 - - 0.00000000000000000000000000000000000002884 151.0
EH1_k127_5409246_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
EH1_k127_5409246_1 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 297.0
EH1_k127_5409246_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004613 247.0
EH1_k127_5416323_0 acid binding OB-fold tRNA helicase-type K07463 - - 1.539e-315 975.0
EH1_k127_5416323_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 450.0
EH1_k127_5416323_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 358.0
EH1_k127_5416323_3 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 327.0
EH1_k127_5416323_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000005675 252.0
EH1_k127_5416323_5 adenyl ribonucleotide binding - - - 0.0000000000000000000000000000000000000000000259 167.0
EH1_k127_5416323_6 - - - - 0.0000000000000000000000000000000000936 134.0
EH1_k127_5416323_7 - - - - 0.000000000000000000000003942 102.0
EH1_k127_5431_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 5.657e-287 888.0
EH1_k127_5431_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 3.906e-235 735.0
EH1_k127_5431_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004432 273.0
EH1_k127_5431_3 Eco57I restriction-modification methylase - - - 0.000000000000000000000000000000000000000000000001345 177.0
EH1_k127_5437659_0 V-type ATP synthase, subunit I K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 351.0
EH1_k127_5437659_1 ATP synthase subunit K K02124 - - 0.000000000000000000000000000000000000000000001659 169.0
EH1_k127_5437659_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000006604 137.0
EH1_k127_5437659_3 PFAM UspA domain protein - - - 0.000000006763 66.0
EH1_k127_5456644_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1309.0
EH1_k127_5456644_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 496.0
EH1_k127_5486142_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 1.015e-263 825.0
EH1_k127_5486142_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 400.0
EH1_k127_5502773_0 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 351.0
EH1_k127_5502773_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 314.0
EH1_k127_5502773_2 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000003424 105.0
EH1_k127_5611870_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 539.0
EH1_k127_5611870_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000006118 225.0
EH1_k127_5633335_0 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 583.0
EH1_k127_5633335_1 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004781 267.0
EH1_k127_5633335_2 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000003511 242.0
EH1_k127_5633335_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000001663 184.0
EH1_k127_5633335_4 - - - - 0.00000000000000000000008111 100.0
EH1_k127_563834_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 556.0
EH1_k127_563834_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 492.0
EH1_k127_563834_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 387.0
EH1_k127_563834_3 RimK domain protein ATP-grasp K05844,K15740 - 6.3.2.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 348.0
EH1_k127_563834_4 Uncharacterised protein family UPF0058 - - - 0.00000000000000000000000000000000000000006707 152.0
EH1_k127_563834_5 Belongs to the UPF0235 family K09131 - - 0.000000000000000000005306 96.0
EH1_k127_5642755_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 2.518e-231 721.0
EH1_k127_5642755_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 551.0
EH1_k127_5642755_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 529.0
EH1_k127_5642755_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000001776 233.0
EH1_k127_5656737_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 2.726e-242 765.0
EH1_k127_5656737_1 PhoU domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 424.0
EH1_k127_5656737_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 399.0
EH1_k127_5656737_3 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 334.0
EH1_k127_5656737_4 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 308.0
EH1_k127_5656737_5 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001489 276.0
EH1_k127_5656737_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003568 246.0
EH1_k127_5656737_7 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.000008864 48.0
EH1_k127_5660104_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 547.0
EH1_k127_5660104_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 427.0
EH1_k127_5660104_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 349.0
EH1_k127_5660104_3 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000004555 156.0
EH1_k127_5662279_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 584.0
EH1_k127_5662279_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 323.0
EH1_k127_5662279_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000006071 107.0
EH1_k127_5662279_3 - - - - 0.000000000002389 73.0
EH1_k127_5677032_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.785e-285 885.0
EH1_k127_5677032_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 6.203e-203 635.0
EH1_k127_5677032_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 345.0
EH1_k127_5677032_3 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 299.0
EH1_k127_5677032_4 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000000000000000000000000000001877 191.0
EH1_k127_5677032_5 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000000000000000006566 183.0
EH1_k127_5677032_6 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000000000000000000004352 167.0
EH1_k127_5677032_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000000000000002872 102.0
EH1_k127_5677032_8 RNA-binding protein involved in rRNA processing K07569 - - 0.000000000000000000001137 96.0
EH1_k127_5677032_9 - - - - 0.000001563 54.0
EH1_k127_5704454_0 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 362.0
EH1_k127_5704454_1 Domain of unknown function (DUF1917) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 293.0
EH1_k127_5704454_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000001251 229.0
EH1_k127_5704454_3 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000000000344 96.0
EH1_k127_5831738_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 535.0
EH1_k127_5831738_1 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 499.0
EH1_k127_5831738_2 methanogen marker protein 4 - - - 0.00000000000000000000000000006112 120.0
EH1_k127_5831738_3 Belongs to the UPF0146 family K09713 - - 0.0000000000000001544 81.0
EH1_k127_5868544_0 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 287.0
EH1_k127_5868544_1 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000000000000000004623 190.0
EH1_k127_5868544_2 TIR domain - - - 0.0000000000000000002296 93.0
EH1_k127_5868544_3 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000007302 70.0
EH1_k127_5911906_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 316.0
EH1_k127_5911906_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000000000002171 209.0
EH1_k127_6391100_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 548.0
EH1_k127_6391100_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 494.0
EH1_k127_6391100_10 Oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009054 269.0
EH1_k127_6391100_11 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006951 267.0
EH1_k127_6391100_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000000000000000000000000001228 168.0
EH1_k127_6391100_13 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000004546 118.0
EH1_k127_6391100_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 460.0
EH1_k127_6391100_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 461.0
EH1_k127_6391100_4 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 442.0
EH1_k127_6391100_5 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 393.0
EH1_k127_6391100_6 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 367.0
EH1_k127_6391100_7 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 367.0
EH1_k127_6391100_8 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 284.0
EH1_k127_6391100_9 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003541 274.0
EH1_k127_6392882_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.112e-222 696.0
EH1_k127_6392882_1 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 587.0
EH1_k127_6395790_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 9.57e-197 621.0
EH1_k127_6395790_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 390.0
EH1_k127_6418561_0 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 386.0
EH1_k127_6418561_1 PFAM zinc iron permease K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 348.0
EH1_k127_6418561_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 342.0
EH1_k127_6418561_3 - - - - 0.0000000000000000000000000000005294 134.0
EH1_k127_6418561_4 Belongs to the glutamate synthase family - - - 0.00000000000000000000000003885 112.0
EH1_k127_6418561_5 Protein of unknown function (DUF2769) - - - 0.0000000000000000000004136 98.0
EH1_k127_6418561_6 - - - - 0.0000000000000004465 81.0
EH1_k127_6418561_7 Ferritin-like domain K03594 - 1.16.3.1 0.000729 44.0
EH1_k127_6423427_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 441.0
EH1_k127_6423427_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 357.0
EH1_k127_6423427_2 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 323.0
EH1_k127_6423427_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 313.0
EH1_k127_6423427_4 PHP-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 303.0
EH1_k127_6423427_5 PFAM TspO MBR family K05770 - - 0.000000000000000000000000000000000000000000000208 171.0
EH1_k127_6424180_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 341.0
EH1_k127_6424180_1 TfuA-like protein - - - 0.000000000000000000000000000000002212 138.0
EH1_k127_6424180_2 Protein of unknown function DUF89 K09116 - - 0.000000000000000000505 87.0
EH1_k127_6424180_3 PFAM Yip1 domain - - - 0.00002515 51.0
EH1_k127_6448832_0 Heat shock 70 kDa protein K04043 - - 4.052e-317 978.0
EH1_k127_6448832_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 432.0
EH1_k127_6448832_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000953 101.0
EH1_k127_6471354_0 DEAD DEAH box helicase domain protein K03725 - - 2.727e-288 899.0
EH1_k127_6471354_1 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.16e-245 767.0
EH1_k127_6471354_10 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000004043 166.0
EH1_k127_6471354_11 membrane K09167 - - 0.0000000000000000000006967 102.0
EH1_k127_6471354_12 - - - - 0.00000000000002307 75.0
EH1_k127_6471354_2 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 9.467e-230 720.0
EH1_k127_6471354_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 557.0
EH1_k127_6471354_4 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 513.0
EH1_k127_6471354_5 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 431.0
EH1_k127_6471354_6 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 417.0
EH1_k127_6471354_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 298.0
EH1_k127_6471354_8 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005347 276.0
EH1_k127_6471354_9 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000006069 233.0
EH1_k127_6480064_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000002085 254.0
EH1_k127_6480064_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004242 243.0
EH1_k127_6480064_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000001303 221.0
EH1_k127_6480064_3 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000003513 180.0
EH1_k127_6480064_4 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000000002599 132.0
EH1_k127_6480064_5 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.000000000000004415 75.0
EH1_k127_6489203_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 555.0
EH1_k127_6489203_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 389.0
EH1_k127_6489203_2 signal transduction protein with CBS domains K07744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001814 278.0
EH1_k127_6489203_3 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000001947 237.0
EH1_k127_6489203_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000001568 89.0
EH1_k127_6508097_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.908e-232 726.0
EH1_k127_6508097_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 589.0
EH1_k127_6508097_10 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000003024 130.0
EH1_k127_6508097_11 - - - - 0.0000000000000000000000003718 108.0
EH1_k127_6508097_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 494.0
EH1_k127_6508097_3 Involved in protein export K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 329.0
EH1_k127_6508097_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001728 231.0
EH1_k127_6508097_5 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.0000000000000000000000000000000000000000000000000000000003766 205.0
EH1_k127_6508097_6 PFAM ABC transporter K16786 - - 0.000000000000000000000000000000000000000000000000000000001761 207.0
EH1_k127_6508097_7 PFAM ABC transporter related K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000005326 201.0
EH1_k127_6508097_8 PFAM BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000005356 189.0
EH1_k127_6508097_9 Protein of unknown function (DUF2551) - - - 0.00000000000000000000000000000004422 128.0
EH1_k127_6512149_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 349.0
EH1_k127_6512149_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000001102 65.0
EH1_k127_6574865_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 4.106e-201 632.0
EH1_k127_6574865_1 domain, Protein K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 435.0
EH1_k127_6574865_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 407.0
EH1_k127_6574865_3 Helix-turn-helix domain protein K03627 - - 0.00000000000000000000000000000000000000000000000006061 184.0
EH1_k127_6596_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 563.0
EH1_k127_6596_1 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 555.0
EH1_k127_6596_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 462.0
EH1_k127_6596_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 420.0
EH1_k127_6596_4 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 344.0
EH1_k127_6596_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 340.0
EH1_k127_6596_6 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 286.0
EH1_k127_6596_7 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
EH1_k127_6596_8 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000008676 167.0
EH1_k127_6596_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000000000757 95.0
EH1_k127_6596854_0 AAA domain - - - 4.536e-242 771.0
EH1_k127_6596854_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 323.0
EH1_k127_6596854_2 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000000005074 111.0
EH1_k127_66310_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 5.46e-198 621.0
EH1_k127_66310_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 419.0
EH1_k127_66310_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 342.0
EH1_k127_66310_3 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 305.0
EH1_k127_66310_4 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 256.0
EH1_k127_66310_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001431 253.0
EH1_k127_66310_6 PFAM peptidase zinc-dependent K06974 - - 0.0000000000000000000000000000000000000000000000000005274 189.0
EH1_k127_66310_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000000000002574 128.0
EH1_k127_66310_8 Belongs to the UPF0146 family K09713 - - 0.000000000000000000000000000003995 128.0
EH1_k127_66310_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000000000003913 91.0
EH1_k127_6662902_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 4.73e-266 835.0
EH1_k127_6662902_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.439e-195 619.0
EH1_k127_6662902_2 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.000000000000000000000000000000000000021 148.0
EH1_k127_6662902_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000103 80.0
EH1_k127_6662902_4 Roadblock LC7 - - - 0.0000000001615 65.0
EH1_k127_6662902_5 Roadblock LC7 K07131 - - 0.0000003296 57.0
EH1_k127_6662902_6 Histidine kinase - - - 0.00001885 53.0
EH1_k127_6688686_0 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 369.0
EH1_k127_6688686_1 Belongs to the MCM family K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 357.0
EH1_k127_6688686_2 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 341.0
EH1_k127_6688686_3 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000001792 130.0
EH1_k127_6688686_4 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000000000008798 109.0
EH1_k127_6728867_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 5.933e-260 806.0
EH1_k127_6728867_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 357.0
EH1_k127_6739675_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.836e-300 930.0
EH1_k127_6739675_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000003433 166.0
EH1_k127_6743677_0 Predicted membrane protein (DUF2070) K08979 - - 7.787e-202 647.0
EH1_k127_6743677_1 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 392.0
EH1_k127_6743677_2 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007869 236.0
EH1_k127_6743677_3 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000045 212.0
EH1_k127_6743677_4 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000000007253 190.0
EH1_k127_6743677_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000002285 193.0
EH1_k127_6811731_0 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 582.0
EH1_k127_6811731_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 438.0
EH1_k127_6823585_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 6.165e-211 661.0
EH1_k127_6823585_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003828 281.0
EH1_k127_6823585_2 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005336 260.0
EH1_k127_6823585_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000002442 228.0
EH1_k127_6823585_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000000000006733 199.0
EH1_k127_6823585_5 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000000002887 134.0
EH1_k127_6823585_6 Binds to the 23S rRNA K02896 - - 0.000000000000000000000000000007774 119.0
EH1_k127_6823585_7 - - - - 0.000000000000000000000003938 106.0
EH1_k127_692650_0 Phosphate transport regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 507.0
EH1_k127_692650_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 469.0
EH1_k127_692650_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 421.0
EH1_k127_692650_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
EH1_k127_692650_4 Domain of unknown function DUF128 K21640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 332.0
EH1_k127_692650_5 PFAM transcriptional regulator TrmB - - - 0.0001109 46.0
EH1_k127_6976_0 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 404.0
EH1_k127_6976_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 380.0
EH1_k127_6976_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 378.0
EH1_k127_6976_3 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 328.0
EH1_k127_6976_4 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004856 276.0
EH1_k127_6976_5 protein conserved in archaea - - - 0.0000000000000000000000000000002052 125.0
EH1_k127_6976_6 - - - - 0.0000000000000001699 81.0
EH1_k127_7063042_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 439.0
EH1_k127_7063042_1 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000003304 200.0
EH1_k127_7063042_2 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000004299 173.0
EH1_k127_7086788_0 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 349.0
EH1_k127_7086788_1 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002262 278.0
EH1_k127_7086788_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007294 275.0
EH1_k127_7086788_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000002608 175.0
EH1_k127_712353_0 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 347.0
EH1_k127_712353_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 325.0
EH1_k127_712353_2 META domain - - - 0.00000000000000000000015 105.0
EH1_k127_7173603_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 411.0
EH1_k127_7173603_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 321.0
EH1_k127_7173603_2 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 298.0
EH1_k127_7173603_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000001483 190.0
EH1_k127_7448308_0 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 377.0
EH1_k127_7448308_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000002186 238.0
EH1_k127_7448308_2 COG1668 ABC-type Na efflux pump, permease component - - - 0.000000000000000000000000000000000000000000000000000000001522 206.0
EH1_k127_7448308_3 RDD family - - - 0.00000000000000000000000000000000000009971 149.0
EH1_k127_7459585_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 552.0
EH1_k127_7459585_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007322 276.0
EH1_k127_7459585_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005382 271.0
EH1_k127_7459585_3 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001967 282.0
EH1_k127_7459585_4 Domain of unknown function DUF123 - - - 0.00000000000000000000000000000000002357 149.0
EH1_k127_7477262_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 1.95e-246 779.0
EH1_k127_7477262_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008094 299.0
EH1_k127_7477262_2 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002758 259.0
EH1_k127_7477262_3 FHA domain containing protein - - - 0.00000000001328 65.0
EH1_k127_7477262_4 cellulose binding - - - 0.00000003145 67.0
EH1_k127_7482839_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 514.0
EH1_k127_7482839_1 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
EH1_k127_7482839_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000000000000000000000000004626 141.0
EH1_k127_7482839_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000105 83.0
EH1_k127_7482839_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000003579 66.0
EH1_k127_7482839_5 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0009869 44.0
EH1_k127_7485114_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 411.0
EH1_k127_7485114_1 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000003991 185.0
EH1_k127_7488468_0 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 1.098e-223 703.0
EH1_k127_7488468_1 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000000000000008204 141.0
EH1_k127_7510316_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.158e-284 891.0
EH1_k127_7510316_1 Involved in regulation of DNA replication K10725 - - 5.301e-219 685.0
EH1_k127_7510316_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 494.0
EH1_k127_7510316_3 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 346.0
EH1_k127_7510316_4 KH domain protein K06961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008912 261.0
EH1_k127_7510316_5 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008963 240.0
EH1_k127_7510316_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000003878 228.0
EH1_k127_7510316_7 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000002108 211.0
EH1_k127_7510316_8 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000000000000000000000000004633 137.0
EH1_k127_7510316_9 PFAM Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000005502 125.0
EH1_k127_7524254_0 Protein of unknown function, DUF255 K06888 - - 1.918e-196 631.0
EH1_k127_7524254_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 482.0
EH1_k127_7539530_0 Domain of unknown function (DUF3821) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 579.0
EH1_k127_7539530_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 405.0
EH1_k127_7539530_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 363.0
EH1_k127_7539530_3 methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 353.0
EH1_k127_7539530_4 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 341.0
EH1_k127_7539530_5 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003916 278.0
EH1_k127_7539530_6 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003221 267.0
EH1_k127_7539530_7 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001228 247.0
EH1_k127_7539530_8 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000005185 172.0
EH1_k127_7598635_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1165.0
EH1_k127_7598635_1 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 281.0
EH1_k127_7598635_2 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002593 271.0
EH1_k127_7598635_3 zinc finger, SWIM - - - 0.00000000000000000000000000000001312 130.0
EH1_k127_7624433_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.893e-251 784.0
EH1_k127_7624433_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000002088 229.0
EH1_k127_7624433_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000003901 163.0
EH1_k127_7624433_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000001369 118.0
EH1_k127_7680881_0 PFAM ABC transporter K00400 - - 1.168e-282 875.0
EH1_k127_7680881_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 399.0
EH1_k127_7680881_2 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 387.0
EH1_k127_7680881_3 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000008623 190.0
EH1_k127_7680881_4 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000786 132.0
EH1_k127_7686235_0 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 372.0
EH1_k127_7686235_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 309.0
EH1_k127_7686235_2 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000573 160.0
EH1_k127_7686235_3 - - - - 0.000000000000000000001716 100.0
EH1_k127_7688671_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 3.678e-243 759.0
EH1_k127_7688671_1 Domain of unknown function (DUF3821) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 327.0
EH1_k127_7734648_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 478.0
EH1_k127_7734648_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007885 285.0
EH1_k127_7734648_2 PFAM Radical SAM - - - 0.0000000001312 62.0
EH1_k127_7818402_0 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000005843 231.0
EH1_k127_7818402_1 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000000000000001807 172.0
EH1_k127_7818402_2 archaeal Zn-finger protein - - - 0.00000000000000000000000000000000000005726 147.0
EH1_k127_7818402_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000001014 55.0
EH1_k127_7832027_0 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 344.0
EH1_k127_7832027_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 319.0
EH1_k127_7846196_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 286.0
EH1_k127_7846196_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 244.0
EH1_k127_7846196_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000005506 231.0
EH1_k127_7846196_3 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000001657 187.0
EH1_k127_7846196_4 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.0000000000000000000000000000000000000000000000000003325 191.0
EH1_k127_7846196_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000001096 179.0
EH1_k127_7846196_6 - - - - 0.0000000000000000000000000000002958 126.0
EH1_k127_7846196_7 - - - - 0.000000000000000000000003263 104.0
EH1_k127_7855414_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 534.0
EH1_k127_7855414_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 527.0
EH1_k127_7855414_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 445.0
EH1_k127_7855414_3 TIGRFAM acetate--CoA ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 425.0
EH1_k127_7855414_4 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 279.0
EH1_k127_7855414_5 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000005698 211.0
EH1_k127_7855414_6 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000000000205 112.0
EH1_k127_7855414_7 PFAM peptidase - - - 0.0000003559 55.0
EH1_k127_7877290_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1838.0
EH1_k127_7877290_1 Radical SAM ThiC family K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 351.0
EH1_k127_7877290_2 - - - - 0.000000007478 58.0
EH1_k127_7895663_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.183e-274 851.0
EH1_k127_7895663_1 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 3.559e-196 625.0
EH1_k127_7980043_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 287.0
EH1_k127_7980043_1 O-methyltransferase K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000372 259.0
EH1_k127_7980043_2 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.00000000000000000000000000000000000000000000000000000000007039 207.0
EH1_k127_7980043_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000005052 117.0
EH1_k127_8000011_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.425e-298 925.0
EH1_k127_8073227_0 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 407.0
EH1_k127_8073227_1 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 317.0
EH1_k127_8073227_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 291.0
EH1_k127_8073227_3 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000001758 201.0
EH1_k127_8073227_4 - - - - 0.0000000000000906 76.0
EH1_k127_8131049_0 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 3.048e-203 639.0
EH1_k127_8131049_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002141 255.0
EH1_k127_8131049_2 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.0000000000000000000000000000000000000000000007894 167.0
EH1_k127_8131049_3 PFAM molydopterin dinucleotide-binding region K00201,K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.00000000000000000000000005671 112.0