Overview

ID MAG01040
Name EH2_bin.17
Sample SMP0029
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family SM23-35
Genus DASPRG01
Species
Assembly information
Completeness (%) 93.24
Contamination (%) 1.18
GC content (%) 42.0
N50 (bp) 7,902
Genome size (bp) 1,566,378

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1586

Gene name Description KEGG GOs EC E-value Score Sequence
EH2_k127_101900_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 8.244e-237 742.0
EH2_k127_101900_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 584.0
EH2_k127_101900_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 535.0
EH2_k127_101900_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 306.0
EH2_k127_101900_4 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000704 164.0
EH2_k127_102509_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 532.0
EH2_k127_102509_1 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 472.0
EH2_k127_102509_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 389.0
EH2_k127_102509_3 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000009946 222.0
EH2_k127_102509_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000004348 211.0
EH2_k127_102509_5 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000001659 203.0
EH2_k127_102509_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000002111 175.0
EH2_k127_102509_7 gas vesicle protein - - - 0.000000000000000000000125 101.0
EH2_k127_103888_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 559.0
EH2_k127_103888_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000002798 196.0
EH2_k127_103888_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000000000002491 140.0
EH2_k127_1044239_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 353.0
EH2_k127_1044239_1 GYD domain - - - 0.00000000000000000000000000001852 119.0
EH2_k127_1044239_2 iron-sulfur cluster assembly - - - 0.000000000000000000000000001618 112.0
EH2_k127_1046929_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 516.0
EH2_k127_1046929_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 310.0
EH2_k127_1046929_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006916 281.0
EH2_k127_1046929_3 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004909 266.0
EH2_k127_1046929_4 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003137 228.0
EH2_k127_1046929_5 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 - - 0.00000000000000000000000000000000000000000003415 163.0
EH2_k127_1046929_6 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000001242 98.0
EH2_k127_1050660_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 495.0
EH2_k127_1050660_1 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 497.0
EH2_k127_1050660_10 Sulfurtransferase TusA - - - 0.0000000000000000000002634 99.0
EH2_k127_1050660_2 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 448.0
EH2_k127_1050660_3 - K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 449.0
EH2_k127_1050660_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 427.0
EH2_k127_1050660_5 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 348.0
EH2_k127_1050660_6 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
EH2_k127_1050660_7 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 308.0
EH2_k127_1050660_8 PFAM diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000004142 184.0
EH2_k127_1050660_9 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000003534 126.0
EH2_k127_1054354_0 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 345.0
EH2_k127_1054354_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 322.0
EH2_k127_1054354_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000009735 211.0
EH2_k127_1054354_3 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000000000000000000000000002366 128.0
EH2_k127_1054354_4 SurA N-terminal domain K03771 - 5.2.1.8 0.000539 43.0
EH2_k127_1059643_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 436.0
EH2_k127_1059643_1 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 362.0
EH2_k127_1059643_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000008612 218.0
EH2_k127_1059643_3 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000001658 143.0
EH2_k127_1059643_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000004582 85.0
EH2_k127_1059643_5 - - - - 0.00000000000000009284 85.0
EH2_k127_106856_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 299.0
EH2_k127_106856_1 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 290.0
EH2_k127_106856_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000005275 220.0
EH2_k127_106856_3 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000002323 184.0
EH2_k127_106856_4 PFAM PilT protein domain protein - - - 0.000000000000000000000000000000000002585 142.0
EH2_k127_106856_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000002685 124.0
EH2_k127_106856_6 Belongs to the ompA family K03286 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000239 115.0
EH2_k127_1081825_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 582.0
EH2_k127_1081825_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 550.0
EH2_k127_1081825_10 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000002395 243.0
EH2_k127_1081825_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009603 244.0
EH2_k127_1081825_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000005456 233.0
EH2_k127_1081825_13 - - - - 0.000000000000000000000000000000000000000000000000000000002375 202.0
EH2_k127_1081825_14 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000003227 181.0
EH2_k127_1081825_15 Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000254 181.0
EH2_k127_1081825_16 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000002979 171.0
EH2_k127_1081825_17 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000003158 178.0
EH2_k127_1081825_19 YgiT-type zinc finger domain protein - - - 0.00000004076 57.0
EH2_k127_1081825_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 538.0
EH2_k127_1081825_20 Domain of unknown function (DUF4258) - - - 0.0001422 45.0
EH2_k127_1081825_3 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 421.0
EH2_k127_1081825_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 422.0
EH2_k127_1081825_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 422.0
EH2_k127_1081825_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 400.0
EH2_k127_1081825_7 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 329.0
EH2_k127_1081825_8 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 289.0
EH2_k127_1081825_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 285.0
EH2_k127_1084013_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.478e-195 618.0
EH2_k127_1084013_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 564.0
EH2_k127_1084013_10 Sporulation and spore germination - - - 0.00000000000000003837 90.0
EH2_k127_1084013_11 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000008995 83.0
EH2_k127_1084013_12 PFAM Copper amine oxidase N-terminal domain K01448 - 3.5.1.28 0.000000000002695 78.0
EH2_k127_1084013_2 UDP-glucose (Heptosyl) LPS alpha 1,3-glucosyltransferase WaaG K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 401.0
EH2_k127_1084013_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 339.0
EH2_k127_1084013_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 323.0
EH2_k127_1084013_5 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001839 276.0
EH2_k127_1084013_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000002556 234.0
EH2_k127_1084013_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000001418 181.0
EH2_k127_1084013_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000001125 148.0
EH2_k127_1084013_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000003838 97.0
EH2_k127_11066_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.484e-316 978.0
EH2_k127_11066_1 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 567.0
EH2_k127_11066_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000002446 224.0
EH2_k127_11066_3 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000118 105.0
EH2_k127_11066_4 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000009367 78.0
EH2_k127_11066_5 - - - - 0.0000000000004171 72.0
EH2_k127_1108264_0 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 283.0
EH2_k127_1108264_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000001857 149.0
EH2_k127_1108264_2 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000001322 151.0
EH2_k127_1108264_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000007977 115.0
EH2_k127_1111003_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 359.0
EH2_k127_1111003_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000003021 271.0
EH2_k127_11114_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1075.0
EH2_k127_11114_1 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 289.0
EH2_k127_11114_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002864 240.0
EH2_k127_11114_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000003023 219.0
EH2_k127_11114_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000004042 199.0
EH2_k127_11114_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000006996 174.0
EH2_k127_11114_7 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000003132 78.0
EH2_k127_1122955_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.154e-216 680.0
EH2_k127_1137959_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000006349 234.0
EH2_k127_1137959_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
EH2_k127_1143003_0 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008129 237.0
EH2_k127_1143003_1 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000007851 180.0
EH2_k127_1143003_2 PFAM DoxX family protein - - - 0.000000000000000000000000000008235 122.0
EH2_k127_1143003_3 PFAM Glycosyl transferase family 2 K09931 - - 0.0000000000000000000149 95.0
EH2_k127_1153327_0 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 1.249e-235 744.0
EH2_k127_1153327_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 590.0
EH2_k127_1153327_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 444.0
EH2_k127_1153327_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 447.0
EH2_k127_1153327_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000001305 177.0
EH2_k127_1153327_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000102 151.0
EH2_k127_1153327_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000001414 127.0
EH2_k127_1153327_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000002249 116.0
EH2_k127_1192885_0 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 355.0
EH2_k127_1192885_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 321.0
EH2_k127_1192885_2 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001559 247.0
EH2_k127_1192885_3 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000001516 215.0
EH2_k127_1199504_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 375.0
EH2_k127_1199504_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000001979 161.0
EH2_k127_1199504_2 PFAM CBS domain K04767 - - 0.0000000002485 67.0
EH2_k127_1215076_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000009858 279.0
EH2_k127_1215076_1 PFAM Cupin 2, conserved barrel domain protein K11312 - - 0.00000000000000000000000000000000000000000007067 163.0
EH2_k127_1216788_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 604.0
EH2_k127_1216788_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 316.0
EH2_k127_1216788_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001063 236.0
EH2_k127_1216788_3 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002216 218.0
EH2_k127_1216788_4 part of a sulfur-relay system K11179 - - 0.00000000002717 66.0
EH2_k127_1235796_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 362.0
EH2_k127_1235796_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007283 285.0
EH2_k127_1235796_2 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000005951 175.0
EH2_k127_1235796_3 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000003702 162.0
EH2_k127_1235796_4 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000002679 117.0
EH2_k127_1235796_5 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000002071 114.0
EH2_k127_1235796_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000009855 91.0
EH2_k127_1235796_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000003028 81.0
EH2_k127_1235796_8 Protein of unknown function (DUF2867) - - - 0.00000004448 58.0
EH2_k127_1245611_0 Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000005159 263.0
EH2_k127_1245611_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000114 87.0
EH2_k127_1271166_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.086e-208 654.0
EH2_k127_1271166_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.273e-196 617.0
EH2_k127_1271166_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 338.0
EH2_k127_1271166_3 MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000921 212.0
EH2_k127_1274030_0 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 476.0
EH2_k127_1274577_0 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 298.0
EH2_k127_1274577_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000008807 192.0
EH2_k127_1274577_2 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000004504 96.0
EH2_k127_1274577_3 FMN binding - - - 0.00004587 46.0
EH2_k127_1281650_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 573.0
EH2_k127_1281650_1 acetyl-CoA catabolic process K00197,K03616 - 2.1.1.245 0.000000000000000000000001513 111.0
EH2_k127_1281650_2 Transcription factor zinc-finger - - - 0.000000000000000000002602 102.0
EH2_k127_1281650_3 - - - - 0.0000000000000001438 86.0
EH2_k127_1312698_0 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 311.0
EH2_k127_1312698_1 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000001146 132.0
EH2_k127_1312698_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000004903 80.0
EH2_k127_1336817_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 486.0
EH2_k127_1336817_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 460.0
EH2_k127_1336817_2 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000001128 218.0
EH2_k127_1336817_3 nucleic acid-binding protein, contains PIN domain K07065 - - 0.00000000000000000000000000000002969 130.0
EH2_k127_1348962_0 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 304.0
EH2_k127_1348962_1 - - - - 0.000000000008768 68.0
EH2_k127_1402701_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.587e-248 772.0
EH2_k127_1402701_1 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 328.0
EH2_k127_1402701_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003377 251.0
EH2_k127_140292_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1039.0
EH2_k127_140292_1 histidine kinase HAMP region domain protein - - - 3.139e-220 718.0
EH2_k127_140292_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000001522 72.0
EH2_k127_140292_11 Protein of unknown function (DUF1573) - - - 0.00000007305 55.0
EH2_k127_140292_2 Diguanylate cyclase - - - 1.591e-198 641.0
EH2_k127_140292_3 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 497.0
EH2_k127_140292_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 389.0
EH2_k127_140292_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 299.0
EH2_k127_140292_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001435 276.0
EH2_k127_140292_7 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008633 226.0
EH2_k127_140292_8 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000008372 108.0
EH2_k127_140292_9 response regulator, receiver - - - 0.0000000000000000000004486 99.0
EH2_k127_143850_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 322.0
EH2_k127_143850_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 289.0
EH2_k127_143850_2 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008234 274.0
EH2_k127_143850_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002335 214.0
EH2_k127_143850_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000231 184.0
EH2_k127_143850_5 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000839 109.0
EH2_k127_143850_6 membrane transporter protein K07090 - - 0.0000009973 51.0
EH2_k127_1440455_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 406.0
EH2_k127_1440455_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000005174 239.0
EH2_k127_1440455_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000002402 205.0
EH2_k127_1442290_0 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000002095 119.0
EH2_k127_1442290_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000008097 65.0
EH2_k127_1442290_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000005312 50.0
EH2_k127_1469097_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 295.0
EH2_k127_1469097_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000003875 214.0
EH2_k127_1469097_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000004922 208.0
EH2_k127_1469097_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000199 158.0
EH2_k127_1469097_4 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000000175 128.0
EH2_k127_1469097_5 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000158 113.0
EH2_k127_1557456_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 446.0
EH2_k127_1557456_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000001742 245.0
EH2_k127_1557456_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000004767 79.0
EH2_k127_1574428_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1312.0
EH2_k127_1574428_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 376.0
EH2_k127_1715886_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002931 234.0
EH2_k127_1715886_1 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000001161 191.0
EH2_k127_1715886_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000205 158.0
EH2_k127_1715886_3 - - - - 0.000000000000000000000000000000001297 134.0
EH2_k127_1715886_4 lyase activity - - - 0.000000000000006383 79.0
EH2_k127_177860_0 Resolvase domain - - - 1.187e-250 790.0
EH2_k127_177860_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007576 569.0
EH2_k127_177860_2 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000005023 239.0
EH2_k127_177860_3 - - - - 0.000000000000000000000000000001148 124.0
EH2_k127_177860_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000004677 78.0
EH2_k127_178366_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.018e-297 930.0
EH2_k127_178366_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.928e-251 802.0
EH2_k127_178366_10 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000007165 254.0
EH2_k127_178366_11 Histidine kinase K00936,K02030 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001826 253.0
EH2_k127_178366_12 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000007069 232.0
EH2_k127_178366_13 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000001691 160.0
EH2_k127_178366_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000009149 133.0
EH2_k127_178366_15 Sulfurtransferase TusA - - - 0.00000000000000000000008991 99.0
EH2_k127_178366_16 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000002845 92.0
EH2_k127_178366_17 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000002027 86.0
EH2_k127_178366_18 PFAM Pilus assembly protein PilO K02664 - - 0.0000000000003772 77.0
EH2_k127_178366_19 Domain of unknown function (DUF4912) K09942 - - 0.0000000000007461 79.0
EH2_k127_178366_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 580.0
EH2_k127_178366_20 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000001183 63.0
EH2_k127_178366_21 Multidrug transporter - - - 0.00000008658 59.0
EH2_k127_178366_22 Pilus assembly protein, PilP K02665 - - 0.000000384 58.0
EH2_k127_178366_24 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.0004132 44.0
EH2_k127_178366_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 469.0
EH2_k127_178366_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 456.0
EH2_k127_178366_5 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 413.0
EH2_k127_178366_6 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 362.0
EH2_k127_178366_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 333.0
EH2_k127_178366_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006749 291.0
EH2_k127_178366_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000004675 252.0
EH2_k127_1801181_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.928e-273 847.0
EH2_k127_1801181_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 6.739e-261 823.0
EH2_k127_1801181_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 386.0
EH2_k127_1801181_3 proteolysis K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000002889 241.0
EH2_k127_1801181_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000001437 135.0
EH2_k127_1801181_5 Chemotaxis protein histidine kinase and related K02487,K06596 - - 0.0000007834 58.0
EH2_k127_1802428_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 587.0
EH2_k127_1802428_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 393.0
EH2_k127_1802428_2 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000001839 121.0
EH2_k127_1802428_3 Cache domain K02482 - 2.7.13.3 0.0000000000000000000001166 100.0
EH2_k127_1802428_4 - - - - 0.00000000001988 70.0
EH2_k127_193547_0 Acyl-CoA synthetase (NDP forming) K09181 - - 2.18e-209 668.0
EH2_k127_193547_1 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 555.0
EH2_k127_193547_2 PFAM DRTGG domain K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 349.0
EH2_k127_193547_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000463 207.0
EH2_k127_193547_4 Transcriptional regulator K02529 - - 0.000000000000001885 81.0
EH2_k127_193547_5 PFAM Uncharacterised protein family UPF0324 - - - 0.000000001 63.0
EH2_k127_2083395_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 329.0
EH2_k127_2093732_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.841e-315 982.0
EH2_k127_2093732_1 PFAM magnesium chelatase ChlI subunit K07391 - - 2.804e-204 647.0
EH2_k127_2093732_2 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 407.0
EH2_k127_2093732_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
EH2_k127_2093732_4 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000004451 64.0
EH2_k127_2095317_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 362.0
EH2_k127_2095317_1 InterPro IPR007367 - - - 0.0000000000000000000000000000000000000000000000000000000000002085 214.0
EH2_k127_2095317_2 - - - - 0.0000000000000000000000000000000000000000000005619 168.0
EH2_k127_2095317_4 peptidyl-tyrosine sulfation - - - 0.000000000002025 77.0
EH2_k127_2096937_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 362.0
EH2_k127_2096937_1 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000000000000005619 168.0
EH2_k127_2096937_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000947 165.0
EH2_k127_2096937_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000009251 109.0
EH2_k127_2108675_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 441.0
EH2_k127_2108675_1 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 295.0
EH2_k127_2108675_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000005937 265.0
EH2_k127_2108675_3 Transcriptional regulator - - - 0.000877 44.0
EH2_k127_2111892_0 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 468.0
EH2_k127_2111892_1 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 295.0
EH2_k127_2131767_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 576.0
EH2_k127_2131767_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 576.0
EH2_k127_2131767_10 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000002831 172.0
EH2_k127_2131767_11 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000006101 155.0
EH2_k127_2131767_12 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000003399 110.0
EH2_k127_2131767_13 Acid phosphatase homologues K19302 - 3.6.1.27 0.0002688 44.0
EH2_k127_2131767_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 520.0
EH2_k127_2131767_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 481.0
EH2_k127_2131767_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 444.0
EH2_k127_2131767_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
EH2_k127_2131767_6 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 315.0
EH2_k127_2131767_7 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000001799 234.0
EH2_k127_2131767_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000002967 227.0
EH2_k127_2131767_9 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000001367 205.0
EH2_k127_2152177_0 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 570.0
EH2_k127_2152177_1 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 367.0
EH2_k127_2152177_10 pilus assembly protein PilW K02459,K02672 - - 0.000005409 56.0
EH2_k127_2152177_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 356.0
EH2_k127_2152177_3 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000009218 210.0
EH2_k127_2152177_4 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000001551 183.0
EH2_k127_2152177_5 General secretion pathway protein M K02462 - - 0.0000000001341 69.0
EH2_k127_2152177_6 general secretion pathway protein K02457 - - 0.0000000001654 67.0
EH2_k127_2152177_7 fimbrial assembly K02461 - - 0.000000008673 68.0
EH2_k127_2152177_8 PFAM Fimbrial assembly K02461 - - 0.00000002003 67.0
EH2_k127_2152177_9 type IV pilus modification protein PilV K02458 - - 0.0000002113 60.0
EH2_k127_2164365_0 Pfam Anion-transporting ATPase K01551 - 3.6.3.16 1.527e-224 710.0
EH2_k127_2164365_1 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000000000115 115.0
EH2_k127_2164365_2 Cytochrome C biogenesis protein - - - 0.000000000000000000000007071 104.0
EH2_k127_2164365_3 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000376 64.0
EH2_k127_2168921_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 595.0
EH2_k127_2168921_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001528 280.0
EH2_k127_2168921_2 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001048 277.0
EH2_k127_2168921_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000003099 162.0
EH2_k127_2168921_4 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000006069 146.0
EH2_k127_2168921_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000002965 116.0
EH2_k127_2168921_6 Peptidase family M50 - - - 0.000000000000000000001102 96.0
EH2_k127_2179995_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 604.0
EH2_k127_2179995_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 522.0
EH2_k127_2179995_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 416.0
EH2_k127_2179995_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000003246 205.0
EH2_k127_2179995_4 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000006998 199.0
EH2_k127_2179995_5 RDD family - - - 0.0000000000000000000000989 103.0
EH2_k127_2180600_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 448.0
EH2_k127_2180600_1 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 347.0
EH2_k127_2180600_2 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 307.0
EH2_k127_2180600_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 314.0
EH2_k127_2180600_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000001893 184.0
EH2_k127_2180600_5 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000004907 186.0
EH2_k127_2180600_6 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000001348 57.0
EH2_k127_2180979_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 516.0
EH2_k127_2180979_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 363.0
EH2_k127_2180979_2 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000001991 159.0
EH2_k127_2180979_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000004352 61.0
EH2_k127_220246_0 lactate metabolic process - - - 5.117e-254 788.0
EH2_k127_220246_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 577.0
EH2_k127_220246_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 392.0
EH2_k127_220246_3 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 359.0
EH2_k127_220246_4 - - - - 0.0000000000000000000000000000000000000000000000000000004041 196.0
EH2_k127_220246_5 Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin K04085 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000006877 57.0
EH2_k127_2212790_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003711 273.0
EH2_k127_2212790_1 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000004788 173.0
EH2_k127_2212790_2 Cold shock K03704 - - 0.000000000000000000000000234 106.0
EH2_k127_2215121_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 7.309e-247 778.0
EH2_k127_2215121_1 TonB dependent receptor K02014 - - 5.983e-238 753.0
EH2_k127_2215121_10 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 371.0
EH2_k127_2215121_11 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 339.0
EH2_k127_2215121_12 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 334.0
EH2_k127_2215121_13 LysM domain K01449,K19223 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000002094 252.0
EH2_k127_2215121_14 response regulator K02485 - - 0.000000000000000000000000000000000000000000000000000000001517 203.0
EH2_k127_2215121_15 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000003951 192.0
EH2_k127_2215121_16 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000004605 190.0
EH2_k127_2215121_17 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000005593 162.0
EH2_k127_2215121_18 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000000000000000000005436 164.0
EH2_k127_2215121_19 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000001634 169.0
EH2_k127_2215121_2 histidine kinase HAMP region domain protein - - - 4.041e-218 710.0
EH2_k127_2215121_20 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000005251 100.0
EH2_k127_2215121_3 TonB dependent receptor K02014 - - 1.299e-209 671.0
EH2_k127_2215121_4 GAF domain - - - 4.268e-197 635.0
EH2_k127_2215121_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 619.0
EH2_k127_2215121_6 hydrogenase large subunit K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 603.0
EH2_k127_2215121_7 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 534.0
EH2_k127_2215121_8 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 539.0
EH2_k127_2215121_9 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 459.0
EH2_k127_2216294_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1179.0
EH2_k127_2216294_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 447.0
EH2_k127_2216294_2 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 307.0
EH2_k127_2216294_3 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 295.0
EH2_k127_2216294_4 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.000000000000000000000000001944 121.0
EH2_k127_222895_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.59e-225 706.0
EH2_k127_222895_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 606.0
EH2_k127_222895_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 372.0
EH2_k127_222895_3 Histidine kinase - - - 0.0000000000000000002792 102.0
EH2_k127_226929_0 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1030.0
EH2_k127_226929_1 FAD binding domain K00394 - 1.8.99.2 8.511e-265 824.0
EH2_k127_226929_2 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 537.0
EH2_k127_226929_3 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 412.0
EH2_k127_2272769_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 524.0
EH2_k127_2272769_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 487.0
EH2_k127_2272769_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 456.0
EH2_k127_2272769_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 326.0
EH2_k127_2272769_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 291.0
EH2_k127_2272769_5 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000001644 141.0
EH2_k127_2272769_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000006948 54.0
EH2_k127_229190_0 DNA integration K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 342.0
EH2_k127_229190_1 ParE-like toxin of type II bacterial toxin-antitoxin system - - - 0.00000000000000000000002622 102.0
EH2_k127_229190_2 Helix-turn-helix domain - - - 0.000000000000002389 79.0
EH2_k127_2299750_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 267.0
EH2_k127_2299750_1 B12 binding domain - - - 0.0000000000000000000007396 97.0
EH2_k127_2308582_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 572.0
EH2_k127_2308582_1 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000004048 239.0
EH2_k127_2308582_2 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000146 212.0
EH2_k127_2308582_3 Fumarase C-terminus K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000006505 194.0
EH2_k127_2308582_4 - - - - 0.000000000000000000000000006179 111.0
EH2_k127_2308582_5 - - - - 0.000000000000000006835 83.0
EH2_k127_2310486_0 Receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 569.0
EH2_k127_2396156_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 496.0
EH2_k127_2396156_1 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000003986 248.0
EH2_k127_2413191_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 5.28e-230 715.0
EH2_k127_2413191_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 4.668e-207 652.0
EH2_k127_2413191_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.031e-198 625.0
EH2_k127_2413191_3 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 557.0
EH2_k127_2413191_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 330.0
EH2_k127_2413191_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000012 208.0
EH2_k127_2413191_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000006938 115.0
EH2_k127_2413191_7 Transporter associated domain K03699 - - 0.000000000000000000255 90.0
EH2_k127_2413191_8 SnoaL-like domain - - - 0.000000000005943 71.0
EH2_k127_2443485_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 350.0
EH2_k127_2443485_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 319.0
EH2_k127_2443485_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000002482 168.0
EH2_k127_2452205_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000000000000000000000000000000002424 148.0
EH2_k127_2452205_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000001893 114.0
EH2_k127_246044_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 8.62e-307 947.0
EH2_k127_246044_1 Dehydratase family K01687 - 4.2.1.9 3.649e-266 828.0
EH2_k127_246044_10 Chromate transporter K07240 - - 0.000000000000000000000000000003137 126.0
EH2_k127_246044_11 PFAM Sulphate transporter K03321 - - 0.0000000000000000000000000003396 117.0
EH2_k127_246044_12 Protein of unknown function (DUF465) K09794 - - 0.000000000000000007554 85.0
EH2_k127_246044_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 610.0
EH2_k127_246044_3 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 569.0
EH2_k127_246044_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 562.0
EH2_k127_246044_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 463.0
EH2_k127_246044_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
EH2_k127_246044_7 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001272 262.0
EH2_k127_246044_8 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000001751 218.0
EH2_k127_246044_9 Chromate transporter K07240 - - 0.000000000000000000000000000000001055 136.0
EH2_k127_2464542_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 5.745e-287 899.0
EH2_k127_2464542_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.832e-240 765.0
EH2_k127_2464542_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 445.0
EH2_k127_2464542_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 374.0
EH2_k127_2464542_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 347.0
EH2_k127_2464542_5 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 335.0
EH2_k127_2464542_6 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000000000000000000289 187.0
EH2_k127_2464542_7 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000003637 68.0
EH2_k127_2492669_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 344.0
EH2_k127_2492669_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000281 272.0
EH2_k127_2492669_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000004156 196.0
EH2_k127_2492669_3 nucleotide metabolic process - - - 0.00000000000000000000000000000000002075 143.0
EH2_k127_2492669_4 AraC-like ligand binding domain - - - 0.000003188 52.0
EH2_k127_2588370_0 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 467.0
EH2_k127_2588370_1 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 291.0
EH2_k127_2588370_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002775 266.0
EH2_k127_2588370_3 Histidine kinase K00936 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000004295 207.0
EH2_k127_2588370_4 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000005402 132.0
EH2_k127_2588370_5 PAS domain - - - 0.00000000000000000000000000008377 120.0
EH2_k127_2588370_6 Cold shock K03704 - - 0.000000000000000000000000002013 112.0
EH2_k127_261696_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 516.0
EH2_k127_261696_1 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 435.0
EH2_k127_261696_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 376.0
EH2_k127_261696_3 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000009597 203.0
EH2_k127_261696_4 lyase activity - - - 0.0000000000000000000000000000000000000000000000000002477 209.0
EH2_k127_261696_5 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000001256 174.0
EH2_k127_261696_6 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000003939 58.0
EH2_k127_261696_7 Membrane - - - 0.0000001177 61.0
EH2_k127_261696_8 DnaJ molecular chaperone homology domain - - - 0.0004264 51.0
EH2_k127_264669_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1259.0
EH2_k127_264669_1 Elongation factor G, domain IV K02355 - - 3.388e-301 938.0
EH2_k127_264669_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.359e-252 787.0
EH2_k127_264669_3 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 603.0
EH2_k127_264669_4 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 468.0
EH2_k127_264669_5 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000159 207.0
EH2_k127_264669_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000001837 151.0
EH2_k127_264669_7 RNA recognition motif - - - 0.000000000000000000000002473 108.0
EH2_k127_264669_8 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002745 76.0
EH2_k127_264669_9 - - - - 0.0004591 45.0
EH2_k127_2661073_0 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000004933 243.0
EH2_k127_2661073_1 - - - - 0.00000000000000000009783 91.0
EH2_k127_2661073_2 nuclease activity K06218 - - 0.000000000000007775 77.0
EH2_k127_2661073_3 Sel1-like repeats. K07126 - - 0.00001268 57.0
EH2_k127_2668889_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 401.0
EH2_k127_2668889_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 298.0
EH2_k127_2668889_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001834 252.0
EH2_k127_26809_0 COG0058 Glucan phosphorylase - - - 6.873e-257 806.0
EH2_k127_26809_1 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.35e-200 646.0
EH2_k127_26809_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002068 235.0
EH2_k127_26809_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005386 239.0
EH2_k127_26809_12 - - - - 0.000000000000000000000000000006414 125.0
EH2_k127_26809_13 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000003352 84.0
EH2_k127_26809_14 Tetratricopeptide repeat - - - 0.00000000000007463 81.0
EH2_k127_26809_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 546.0
EH2_k127_26809_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 538.0
EH2_k127_26809_4 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 507.0
EH2_k127_26809_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 429.0
EH2_k127_26809_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 392.0
EH2_k127_26809_7 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 378.0
EH2_k127_26809_8 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005075 264.0
EH2_k127_26809_9 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001942 268.0
EH2_k127_2736204_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 578.0
EH2_k127_2736204_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000008208 213.0
EH2_k127_2736204_2 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000009777 154.0
EH2_k127_2746369_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 524.0
EH2_k127_2746369_1 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 493.0
EH2_k127_2746369_2 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 356.0
EH2_k127_2746369_3 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 319.0
EH2_k127_2746369_4 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000003196 214.0
EH2_k127_2746369_5 Type II/IV secretion system protein K02454,K02652 - - 0.00000000000008574 72.0
EH2_k127_28054_0 Aminotransferase class-III K01845 - 5.4.3.8 1.862e-203 639.0
EH2_k127_28054_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003171 242.0
EH2_k127_28054_2 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000007074 66.0
EH2_k127_28054_3 ACT domain - - - 0.00000479 55.0
EH2_k127_3041996_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 1.149e-196 616.0
EH2_k127_3041996_1 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 493.0
EH2_k127_3041996_2 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 334.0
EH2_k127_3041996_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 317.0
EH2_k127_30645_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 583.0
EH2_k127_30645_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 534.0
EH2_k127_30645_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 464.0
EH2_k127_30645_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 341.0
EH2_k127_30645_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 323.0
EH2_k127_30645_5 Glutaredoxin K03676 - - 0.00000000000000004601 81.0
EH2_k127_30645_6 cellulose binding - - - 0.0000000000000008151 87.0
EH2_k127_3100040_1 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000001238 87.0
EH2_k127_3100040_2 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000006421 78.0
EH2_k127_3116780_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006793 269.0
EH2_k127_3116780_1 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000001844 209.0
EH2_k127_3116780_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000002395 79.0
EH2_k127_3121698_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 581.0
EH2_k127_3121698_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 512.0
EH2_k127_3121698_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 448.0
EH2_k127_3121698_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 319.0
EH2_k127_3121698_4 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006717 273.0
EH2_k127_3121698_5 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000000000003396 171.0
EH2_k127_3121698_6 Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000001459 178.0
EH2_k127_3121698_7 - - - - 0.000000000000000000000000002472 115.0
EH2_k127_3121698_8 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.00009243 46.0
EH2_k127_3121698_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0003237 50.0
EH2_k127_3123186_0 DNA restriction-modification system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 535.0
EH2_k127_3123186_1 Restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002891 273.0
EH2_k127_3123186_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000002625 182.0
EH2_k127_3123186_3 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000007685 150.0
EH2_k127_3123186_4 - - - - 0.000000000000004932 78.0
EH2_k127_3125934_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001145 252.0
EH2_k127_3125934_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000001178 185.0
EH2_k127_3125934_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000002417 179.0
EH2_k127_3126310_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.72e-200 629.0
EH2_k127_3126310_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 552.0
EH2_k127_3126310_10 AMP binding - - - 0.0000000000000000000000000000001048 128.0
EH2_k127_3126310_11 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000009989 113.0
EH2_k127_3126310_12 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000000003853 94.0
EH2_k127_3126310_2 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 407.0
EH2_k127_3126310_3 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 284.0
EH2_k127_3126310_4 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
EH2_k127_3126310_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000333 241.0
EH2_k127_3126310_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
EH2_k127_3126310_7 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000004975 212.0
EH2_k127_3126310_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000006856 196.0
EH2_k127_3126310_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000009482 143.0
EH2_k127_3131981_0 hmm pf01609 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002372 249.0
EH2_k127_3131981_1 Metalloenzyme superfamily - - - 0.000004603 53.0
EH2_k127_3139514_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.388e-230 749.0
EH2_k127_3139514_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 362.0
EH2_k127_3158078_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 610.0
EH2_k127_3158078_1 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 514.0
EH2_k127_3158078_10 - - - - 0.00000000007685 65.0
EH2_k127_3158078_2 pyridine nucleotide-disulphide oxidoreductase dimerisation K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 471.0
EH2_k127_3158078_3 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 316.0
EH2_k127_3158078_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000177 292.0
EH2_k127_3158078_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003025 266.0
EH2_k127_3158078_6 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001356 230.0
EH2_k127_3158078_7 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000007939 137.0
EH2_k127_3158078_8 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000000000002263 114.0
EH2_k127_3158078_9 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000007526 87.0
EH2_k127_3158195_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 585.0
EH2_k127_3158195_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 575.0
EH2_k127_3158195_10 Phospholipid methyltransferase - - - 0.00000000000000003179 90.0
EH2_k127_3158195_12 Protein of unknown function (DUF2934) - - - 0.000001142 56.0
EH2_k127_3158195_2 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 516.0
EH2_k127_3158195_3 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 345.0
EH2_k127_3158195_4 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
EH2_k127_3158195_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000001174 238.0
EH2_k127_3158195_6 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000001857 113.0
EH2_k127_3158195_7 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000009205 111.0
EH2_k127_3158195_8 RNase H - - - 0.000000000000000000000001303 110.0
EH2_k127_3158195_9 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001316 106.0
EH2_k127_3159621_0 FAD binding domain K00278 - 1.4.3.16 2.033e-204 650.0
EH2_k127_3159621_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 523.0
EH2_k127_3159621_10 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003937 286.0
EH2_k127_3159621_11 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000452 285.0
EH2_k127_3159621_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006396 289.0
EH2_k127_3159621_13 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002132 250.0
EH2_k127_3159621_14 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002875 259.0
EH2_k127_3159621_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000001089 243.0
EH2_k127_3159621_16 electron transfer activity K02305,K08738 - - 0.0000000000000000000000000000000000000000000000000000000001267 208.0
EH2_k127_3159621_17 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000004671 209.0
EH2_k127_3159621_18 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000004853 201.0
EH2_k127_3159621_19 PIN domain - - - 0.00000000000000000000000000000000000000000000000004144 181.0
EH2_k127_3159621_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 464.0
EH2_k127_3159621_20 phosphatase activity K05967 - - 0.00000000000000000000000000000000000000000000000005447 184.0
EH2_k127_3159621_22 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000004779 120.0
EH2_k127_3159621_23 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000006076 116.0
EH2_k127_3159621_24 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000005972 88.0
EH2_k127_3159621_25 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000002827 73.0
EH2_k127_3159621_26 Transposase IS200 like K07491 - - 0.0000000000001051 72.0
EH2_k127_3159621_28 PFAM Uncharacterised protein family UPF0150 - - - 0.0002478 46.0
EH2_k127_3159621_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 454.0
EH2_k127_3159621_4 phage Terminase large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 449.0
EH2_k127_3159621_5 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 399.0
EH2_k127_3159621_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 379.0
EH2_k127_3159621_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 360.0
EH2_k127_3159621_8 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 338.0
EH2_k127_3159621_9 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 320.0
EH2_k127_3163866_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 330.0
EH2_k127_3163866_1 Domain of unknown function (DUF1844) - - - 0.000000001482 61.0
EH2_k127_3163866_2 galactose-1-phosphate K00965 - 2.7.7.12 0.0004132 43.0
EH2_k127_3164693_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.076e-207 652.0
EH2_k127_3164693_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 519.0
EH2_k127_3164693_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000004845 195.0
EH2_k127_3164693_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 403.0
EH2_k127_3164693_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 366.0
EH2_k127_3164693_4 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 329.0
EH2_k127_3164693_5 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001421 284.0
EH2_k127_3164693_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000003941 251.0
EH2_k127_3164693_7 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001124 242.0
EH2_k127_3164693_8 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000006947 210.0
EH2_k127_3164693_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000009493 199.0
EH2_k127_3189987_0 carbon starvation protein CstA K06200 - - 9.853e-258 809.0
EH2_k127_3189987_1 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 565.0
EH2_k127_3189987_10 Universal stress protein family - - - 0.000000000000000000000000000000000000000000001442 169.0
EH2_k127_3189987_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000001102 171.0
EH2_k127_3189987_12 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000003965 165.0
EH2_k127_3189987_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.000000000000000000000000000000000000001019 159.0
EH2_k127_3189987_14 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000004538 144.0
EH2_k127_3189987_15 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000007541 133.0
EH2_k127_3189987_16 proteolysis K03665 - - 0.000000000000000000000000000544 119.0
EH2_k127_3189987_17 - - - - 0.0000000000000000000000000013 113.0
EH2_k127_3189987_18 PFAM peptidase U32 K08303 - - 0.00000000000007826 74.0
EH2_k127_3189987_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 334.0
EH2_k127_3189987_3 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 324.0
EH2_k127_3189987_4 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 321.0
EH2_k127_3189987_5 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 293.0
EH2_k127_3189987_6 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000004109 271.0
EH2_k127_3189987_7 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007398 260.0
EH2_k127_3189987_8 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001314 257.0
EH2_k127_3189987_9 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000001429 241.0
EH2_k127_3199022_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 329.0
EH2_k127_3199022_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001782 245.0
EH2_k127_3199022_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000006163 168.0
EH2_k127_3199022_3 ATP-dependent helicase deoxyribonuclease subunit B K16899 - 3.6.4.12 0.0000002932 63.0
EH2_k127_3209906_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000004474 202.0
EH2_k127_3209906_1 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000002358 145.0
EH2_k127_3210783_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002672 289.0
EH2_k127_3210783_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000008655 197.0
EH2_k127_3210783_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000001986 83.0
EH2_k127_3210783_3 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00005384 51.0
EH2_k127_3211416_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 8.248e-266 831.0
EH2_k127_3211416_1 Glycosyl hydrolases family 15 - - - 8.146e-251 790.0
EH2_k127_3211416_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000004257 174.0
EH2_k127_3211416_11 domain protein - - - 0.0000000000000000000000000000000000000000003239 168.0
EH2_k127_3211416_12 methyltransferase activity - - - 0.00000000000000000000000000000000000000001991 159.0
EH2_k127_3211416_13 Rubrerythrin - - - 0.0000000000000000000000000000002129 125.0
EH2_k127_3211416_14 electron transfer activity K00428 - 1.11.1.5 0.00000000000000000000000003387 113.0
EH2_k127_3211416_15 Protein of unknown function (DUF2769) - - - 0.0000000000000001869 81.0
EH2_k127_3211416_16 Putative regulatory protein - - - 0.0000002615 54.0
EH2_k127_3211416_18 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0005343 46.0
EH2_k127_3211416_2 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 492.0
EH2_k127_3211416_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 447.0
EH2_k127_3211416_4 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 414.0
EH2_k127_3211416_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 322.0
EH2_k127_3211416_6 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 306.0
EH2_k127_3211416_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000006326 271.0
EH2_k127_3211416_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000004102 216.0
EH2_k127_3211416_9 - - - - 0.00000000000000000000000000000000000000000000000000005047 190.0
EH2_k127_3213611_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.425e-243 770.0
EH2_k127_3213611_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.371e-220 699.0
EH2_k127_3213611_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000002141 188.0
EH2_k127_3213611_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00003317 47.0
EH2_k127_3230848_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 397.0
EH2_k127_3230848_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 318.0
EH2_k127_3241088_0 Belongs to the GPI family K01810 - 5.3.1.9 1.029e-292 905.0
EH2_k127_3241088_1 YMGG-like Gly-zipper - - - 0.0000000366 63.0
EH2_k127_3241088_2 oxidation-reduction process - - - 0.0003691 48.0
EH2_k127_3271439_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1098.0
EH2_k127_3271439_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 325.0
EH2_k127_3271439_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000004248 208.0
EH2_k127_3274238_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1552.0
EH2_k127_3274238_1 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000009533 194.0
EH2_k127_3276171_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0 1115.0
EH2_k127_3276171_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 2.203e-232 742.0
EH2_k127_3276171_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 421.0
EH2_k127_3276171_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004625 240.0
EH2_k127_3276171_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00007344 45.0
EH2_k127_3300051_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000001013 251.0
EH2_k127_3300051_2 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000003071 65.0
EH2_k127_333713_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1073.0
EH2_k127_333713_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 296.0
EH2_k127_333713_2 protein localization to T-tubule K10380,K15503,K21440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002131 259.0
EH2_k127_333713_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000002015 132.0
EH2_k127_3366635_0 PIN domain - - - 0.00000000000000000000000004391 111.0
EH2_k127_3366635_1 metal-dependent phosphohydrolase HD sub domain K07814,K13815 - - 0.0000000000000005634 89.0
EH2_k127_3366635_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000051 54.0
EH2_k127_3366635_3 - - - - 0.0003777 51.0
EH2_k127_3368455_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 368.0
EH2_k127_3368455_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000007086 234.0
EH2_k127_3368455_2 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000002909 145.0
EH2_k127_3368455_3 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000002645 100.0
EH2_k127_3379394_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.976e-198 634.0
EH2_k127_3404569_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 496.0
EH2_k127_3404569_1 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000001056 243.0
EH2_k127_3404569_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000006236 191.0
EH2_k127_3404569_3 RNA recognition motif - - - 0.000000000000000000000000003996 114.0
EH2_k127_3404569_4 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000316 44.0
EH2_k127_3441263_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1103.0
EH2_k127_3441263_1 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 480.0
EH2_k127_3441263_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 388.0
EH2_k127_3441263_3 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000003227 181.0
EH2_k127_3441263_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000004451 137.0
EH2_k127_3446727_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 364.0
EH2_k127_3446727_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 291.0
EH2_k127_3459187_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000435 264.0
EH2_k127_3459187_1 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000004419 225.0
EH2_k127_3459187_2 Thioredoxin - - - 0.00000000000000000000000000000000001534 139.0
EH2_k127_3459187_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0006817 46.0
EH2_k127_347546_0 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 484.0
EH2_k127_347546_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001655 164.0
EH2_k127_3504492_0 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 450.0
EH2_k127_3504492_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001395 222.0
EH2_k127_3504492_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000001102 163.0
EH2_k127_3504492_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000001788 148.0
EH2_k127_3504492_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000008003 142.0
EH2_k127_3504492_5 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000002728 139.0
EH2_k127_3504492_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000002958 64.0
EH2_k127_352732_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 545.0
EH2_k127_352732_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 544.0
EH2_k127_352732_10 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000001551 121.0
EH2_k127_352732_11 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000001213 102.0
EH2_k127_352732_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 381.0
EH2_k127_352732_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 323.0
EH2_k127_352732_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 314.0
EH2_k127_352732_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
EH2_k127_352732_6 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000303 249.0
EH2_k127_352732_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000001144 243.0
EH2_k127_352732_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000001663 203.0
EH2_k127_352732_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000002741 172.0
EH2_k127_3533080_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 523.0
EH2_k127_3533080_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 447.0
EH2_k127_3533080_10 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000000000000007754 171.0
EH2_k127_3533080_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000006466 155.0
EH2_k127_3533080_12 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000003007 148.0
EH2_k127_3533080_13 - - - - 0.000000000000000000000000000001792 124.0
EH2_k127_3533080_14 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000003511 122.0
EH2_k127_3533080_15 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000000000491 104.0
EH2_k127_3533080_16 nucleotidyltransferase activity K07075 - - 0.000000000000000000002888 96.0
EH2_k127_3533080_18 Regulatory protein, FmdB family - - - 0.00000000000000001063 86.0
EH2_k127_3533080_2 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 404.0
EH2_k127_3533080_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 337.0
EH2_k127_3533080_4 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 240.0
EH2_k127_3533080_5 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000001089 229.0
EH2_k127_3533080_6 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000003693 241.0
EH2_k127_3533080_7 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000798 240.0
EH2_k127_3533080_8 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000003509 209.0
EH2_k127_3533080_9 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000000002846 172.0
EH2_k127_354022_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 311.0
EH2_k127_354022_1 Response regulator, receiver K11443 - - 0.000000000000000000000000000000000000000000000001125 177.0
EH2_k127_38190_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.218e-267 856.0
EH2_k127_38190_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 362.0
EH2_k127_38190_2 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002122 266.0
EH2_k127_38190_3 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000001737 158.0
EH2_k127_3837677_0 Protein conserved in bacteria - - - 5.914e-247 788.0
EH2_k127_3837677_1 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000146 119.0
EH2_k127_3889117_0 COGs COG3328 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 432.0
EH2_k127_3889117_1 PFAM MgtC SapB transporter K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006407 258.0
EH2_k127_3889117_2 Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000007612 143.0
EH2_k127_3889117_3 - - - - 0.00000000000000004045 84.0
EH2_k127_3889117_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000116 79.0
EH2_k127_3889117_5 transposase K05349 - 3.2.1.21 0.000000000000002274 86.0
EH2_k127_3889117_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000002738 50.0
EH2_k127_406701_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 588.0
EH2_k127_406701_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000485 204.0
EH2_k127_4115509_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 492.0
EH2_k127_4115509_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 427.0
EH2_k127_4115509_2 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 421.0
EH2_k127_4115509_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000001984 193.0
EH2_k127_4115509_4 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000000001423 131.0
EH2_k127_4115509_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000005615 114.0
EH2_k127_4115509_6 - - - - 0.00000000009672 64.0
EH2_k127_4115509_7 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.0000000006747 69.0
EH2_k127_4115509_8 Peptide synthetase K04789 - - 0.00004721 48.0
EH2_k127_4134197_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 451.0
EH2_k127_4134197_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 352.0
EH2_k127_4134197_10 Sigma factor PP2C-like phosphatases - - - 0.00000000008844 73.0
EH2_k127_4134197_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 350.0
EH2_k127_4134197_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 307.0
EH2_k127_4134197_4 Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003769 264.0
EH2_k127_4134197_5 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000001308 221.0
EH2_k127_4134197_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
EH2_k127_4134197_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000001623 183.0
EH2_k127_4134197_8 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000006303 128.0
EH2_k127_4134197_9 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000001101 114.0
EH2_k127_415210_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000744 278.0
EH2_k127_415210_1 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.0000000001515 72.0
EH2_k127_415210_2 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0002817 44.0
EH2_k127_4163267_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1097.0
EH2_k127_4168097_0 Anion-transporting ATPase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 302.0
EH2_k127_4168097_1 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000001003 149.0
EH2_k127_4168097_2 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000009172 66.0
EH2_k127_4170539_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 597.0
EH2_k127_4170539_1 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 456.0
EH2_k127_4170539_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 299.0
EH2_k127_4170539_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 299.0
EH2_k127_4170539_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001215 282.0
EH2_k127_4170539_5 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000006707 179.0
EH2_k127_4170539_6 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000009994 132.0
EH2_k127_4170539_7 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000001343 110.0
EH2_k127_4170539_8 hydrogenase maturation protease K03605 - - 0.0000000000000000000002375 103.0
EH2_k127_4211703_0 Telomere recombination K04656 - - 3.056e-265 838.0
EH2_k127_4211703_1 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 459.0
EH2_k127_4211703_10 nickel cation binding K04651,K19640 - - 0.00000000000000000000000000004541 120.0
EH2_k127_4211703_11 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000005113 113.0
EH2_k127_4211703_12 lyase activity - - - 0.00000000000000000000005224 114.0
EH2_k127_4211703_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000005767 72.0
EH2_k127_4211703_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 443.0
EH2_k127_4211703_3 AIR synthase related protein, N-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 374.0
EH2_k127_4211703_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 355.0
EH2_k127_4211703_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 312.0
EH2_k127_4211703_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 287.0
EH2_k127_4211703_7 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005039 252.0
EH2_k127_4211703_8 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006261 250.0
EH2_k127_42183_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 1.723e-228 732.0
EH2_k127_42183_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 555.0
EH2_k127_42183_11 hydrogenase large subunit K06281 - 1.12.99.6 0.0000000000000000000000003277 105.0
EH2_k127_42183_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000008186 93.0
EH2_k127_42183_14 DNA methylase K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 0.00000000007072 65.0
EH2_k127_42183_2 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 419.0
EH2_k127_42183_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 372.0
EH2_k127_42183_4 PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 322.0
EH2_k127_42183_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 268.0
EH2_k127_42183_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000001235 230.0
EH2_k127_42183_7 hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000008709 180.0
EH2_k127_42183_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000199 164.0
EH2_k127_42183_9 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000002512 136.0
EH2_k127_4220328_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 361.0
EH2_k127_4220328_1 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000003392 252.0
EH2_k127_4220328_2 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000004839 200.0
EH2_k127_4220328_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000001042 167.0
EH2_k127_4220328_4 - - - - 0.00000002045 55.0
EH2_k127_4224468_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.21e-210 660.0
EH2_k127_4224468_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 545.0
EH2_k127_4224468_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 387.0
EH2_k127_4224468_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 370.0
EH2_k127_4224468_4 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 345.0
EH2_k127_4224468_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000002936 203.0
EH2_k127_4224468_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000001505 144.0
EH2_k127_4227709_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 610.0
EH2_k127_4227709_1 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003652 255.0
EH2_k127_4227709_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000003221 226.0
EH2_k127_4227709_3 - - - - 0.00000000000000000000000001152 111.0
EH2_k127_4241662_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 402.0
EH2_k127_4241662_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 294.0
EH2_k127_4241662_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 285.0
EH2_k127_4241662_3 PFAM Sporulation related domain - - - 0.0002629 52.0
EH2_k127_42490_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1037.0
EH2_k127_42490_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 8.406e-279 869.0
EH2_k127_42490_10 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000002399 178.0
EH2_k127_42490_11 PBS lyase HEAT-like repeat - - - 0.0000000000000000000008835 102.0
EH2_k127_42490_12 Belongs to the UPF0434 family K09791 - - 0.0000000000000003914 79.0
EH2_k127_42490_13 Protein conserved in bacteria - - - 0.00005064 49.0
EH2_k127_42490_2 Phosphoglycerate kinase K00927 - 2.7.2.3 8.482e-198 624.0
EH2_k127_42490_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 355.0
EH2_k127_42490_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 337.0
EH2_k127_42490_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000125 291.0
EH2_k127_42490_6 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001188 252.0
EH2_k127_42490_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000002588 232.0
EH2_k127_42490_8 - - - - 0.0000000000000000000000000000000000000000000000000000007735 202.0
EH2_k127_42490_9 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000009068 199.0
EH2_k127_4249952_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 384.0
EH2_k127_4249952_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 359.0
EH2_k127_4249952_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000005592 89.0
EH2_k127_4255883_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 5.656e-200 636.0
EH2_k127_4255883_1 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 563.0
EH2_k127_4255883_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008263 279.0
EH2_k127_4260194_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 420.0
EH2_k127_4260194_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 340.0
EH2_k127_4260194_2 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 288.0
EH2_k127_4260194_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006902 267.0
EH2_k127_4260194_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000009047 229.0
EH2_k127_4260194_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000005427 186.0
EH2_k127_4260194_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000003634 124.0
EH2_k127_42739_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1321.0
EH2_k127_42739_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000005977 156.0
EH2_k127_42739_2 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000006079 130.0
EH2_k127_42739_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001178 123.0
EH2_k127_4283475_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 317.0
EH2_k127_4283475_1 Glycosyl transferase family 2 K09931 - - 0.0000000000000000000000000000000000000001138 154.0
EH2_k127_4283475_2 membrane transporter protein K07090 - - 0.000000000003836 68.0
EH2_k127_4353960_0 GTP-binding protein TypA K06207 - - 3.359e-264 826.0
EH2_k127_4405781_0 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 372.0
EH2_k127_4405781_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001874 287.0
EH2_k127_4405781_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000005083 179.0
EH2_k127_4405781_3 Oxidoreductase NAD-binding domain K02823 - - 0.00000000000000000000000000000001161 133.0
EH2_k127_4405781_4 Protein of unknown function (DUF2934) - - - 0.000002198 52.0
EH2_k127_45045_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 308.0
EH2_k127_45045_1 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000007343 215.0
EH2_k127_45045_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000001387 154.0
EH2_k127_45045_3 RNA recognition motif - - - 0.0000000000000000000000001266 109.0
EH2_k127_45045_4 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000002253 91.0
EH2_k127_4530068_0 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 522.0
EH2_k127_4533147_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 571.0
EH2_k127_4533147_1 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 511.0
EH2_k127_4533147_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 287.0
EH2_k127_4533147_3 HEPN domain - - - 0.0000000000000000000000000000000003999 136.0
EH2_k127_4533147_4 Nucleotidyltransferase domain K07076 - - 0.00000000000000000000000000000002254 128.0
EH2_k127_4550484_0 Bacterial PH domain - - - 0.000000000000001512 82.0
EH2_k127_4550484_1 transposase activity - - - 0.000000000001843 68.0
EH2_k127_4550484_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000001487 64.0
EH2_k127_456887_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.039e-207 648.0
EH2_k127_456887_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003728 258.0
EH2_k127_456887_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000006939 149.0
EH2_k127_456887_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000001899 109.0
EH2_k127_456887_4 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000363 93.0
EH2_k127_4595633_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 4.993e-217 683.0
EH2_k127_4595633_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 2.002e-211 668.0
EH2_k127_4595633_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 487.0
EH2_k127_4595633_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 449.0
EH2_k127_4595633_4 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 430.0
EH2_k127_4595633_5 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 360.0
EH2_k127_4595633_6 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001899 259.0
EH2_k127_4595633_7 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000122 215.0
EH2_k127_4595633_8 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000001628 206.0
EH2_k127_4595633_9 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000000000002928 178.0
EH2_k127_460191_0 PFAM ferredoxin-dependent glutamate synthase - - - 3.105e-295 911.0
EH2_k127_460191_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 396.0
EH2_k127_460191_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 398.0
EH2_k127_4631241_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 622.0
EH2_k127_4631241_1 Mediates influx of magnesium ions K03284 - - 0.000000000004152 66.0
EH2_k127_4789838_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 409.0
EH2_k127_4789838_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 367.0
EH2_k127_4789838_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001508 282.0
EH2_k127_4789838_3 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003405 257.0
EH2_k127_4789838_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000001444 211.0
EH2_k127_4789838_5 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000002428 216.0
EH2_k127_4789838_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000006978 165.0
EH2_k127_4789838_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000005834 155.0
EH2_k127_4809820_0 - - - - 0.0000000000000000000000000000000000000054 158.0
EH2_k127_4809820_1 - - - - 0.0000000000000000000000008425 114.0
EH2_k127_4854866_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 6.789e-233 729.0
EH2_k127_4854866_1 GYD domain - - - 0.0000000000000000000000000000000000000111 146.0
EH2_k127_4958559_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.362e-288 906.0
EH2_k127_4958559_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 529.0
EH2_k127_4958559_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 396.0
EH2_k127_4958559_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 339.0
EH2_k127_497465_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 4.047e-267 841.0
EH2_k127_497465_1 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 526.0
EH2_k127_497465_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 374.0
EH2_k127_5083352_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 452.0
EH2_k127_5083352_1 TIGRFAM addiction module toxin, RelE StbE family K06218 - - 0.00000000004425 67.0
EH2_k127_5083352_2 Type II restriction enzyme, methylase subunits - - - 0.00001041 48.0
EH2_k127_514043_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 541.0
EH2_k127_514043_1 Competence protein K02238 - - 0.000000000000000000000000000000000000000000007853 179.0
EH2_k127_514043_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000003472 159.0
EH2_k127_514043_3 YbbR-like protein - - - 0.000000000000000000000000000000000000003836 153.0
EH2_k127_5182925_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 449.0
EH2_k127_5182925_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 383.0
EH2_k127_5182925_2 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 385.0
EH2_k127_5182925_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000004175 127.0
EH2_k127_5198310_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 5.812e-209 680.0
EH2_k127_5198310_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000494 272.0
EH2_k127_5198310_2 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
EH2_k127_5198310_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001088 260.0
EH2_k127_5198310_4 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001594 237.0
EH2_k127_5198310_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000001006 198.0
EH2_k127_5198310_6 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000003237 194.0
EH2_k127_5198310_7 B12 binding domain - - - 0.00000000000000000000000000000000001141 143.0
EH2_k127_5198310_8 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.0000000000000000000000000000000000374 143.0
EH2_k127_5226922_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 1.036e-278 882.0
EH2_k127_5226922_1 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 588.0
EH2_k127_5226922_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 450.0
EH2_k127_5226922_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 326.0
EH2_k127_5226922_4 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004079 283.0
EH2_k127_5226922_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000001501 203.0
EH2_k127_5226922_6 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000001238 183.0
EH2_k127_5226922_7 Thiamine-binding protein - - - 0.00000000000000000000000000000000001626 137.0
EH2_k127_5226922_8 diguanylate cyclase - - - 0.00000000000000000000000000000000009304 151.0
EH2_k127_5226922_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000008519 126.0
EH2_k127_5227109_2 Gnat family - - - 0.0000000151 62.0
EH2_k127_5253222_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.914e-280 870.0
EH2_k127_5253222_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 415.0
EH2_k127_5253222_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000373 177.0
EH2_k127_5253222_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000001877 149.0
EH2_k127_5253222_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000001061 90.0
EH2_k127_5259997_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1189.0
EH2_k127_5259997_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1173.0
EH2_k127_5259997_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 488.0
EH2_k127_5259997_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000003922 238.0
EH2_k127_5259997_4 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
EH2_k127_5259997_5 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000001022 171.0
EH2_k127_5259997_6 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000005941 160.0
EH2_k127_5259997_7 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000001266 135.0
EH2_k127_5262007_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 358.0
EH2_k127_5262007_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008889 267.0
EH2_k127_5262007_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000107 208.0
EH2_k127_526423_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.432e-252 801.0
EH2_k127_526423_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.965e-204 642.0
EH2_k127_526423_10 COG3209 Rhs family protein - - - 0.0000000000000000000000000008708 116.0
EH2_k127_526423_11 cellulose binding K01179 - 3.2.1.4 0.00000000000000000001544 104.0
EH2_k127_526423_12 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000009163 93.0
EH2_k127_526423_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 574.0
EH2_k127_526423_3 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 334.0
EH2_k127_526423_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009382 278.0
EH2_k127_526423_5 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000000002768 241.0
EH2_k127_526423_6 deoxyribose-phosphate aldolase activity K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000001448 231.0
EH2_k127_526423_7 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000231 184.0
EH2_k127_526423_8 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000506 183.0
EH2_k127_526423_9 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000009053 155.0
EH2_k127_5290450_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 3.147e-248 778.0
EH2_k127_5290450_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 380.0
EH2_k127_5290450_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000002344 226.0
EH2_k127_5290450_3 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000000007684 167.0
EH2_k127_5292480_0 DNA polymerase K02347 - - 3.611e-235 740.0
EH2_k127_5316635_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 426.0
EH2_k127_5316635_1 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0005763 44.0
EH2_k127_5317657_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.173e-215 674.0
EH2_k127_5317657_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 454.0
EH2_k127_5317657_10 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000000000003389 115.0
EH2_k127_5317657_11 - - - - 0.00000000000000000000176 96.0
EH2_k127_5317657_12 COG NOG14552 non supervised orthologous group - - - 0.000000000000000006835 83.0
EH2_k127_5317657_13 - - - - 0.0000000000000008131 77.0
EH2_k127_5317657_14 - - - - 0.00000000001078 66.0
EH2_k127_5317657_15 - - - - 0.00000001557 57.0
EH2_k127_5317657_2 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 374.0
EH2_k127_5317657_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003889 252.0
EH2_k127_5317657_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000005211 243.0
EH2_k127_5317657_5 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000004532 230.0
EH2_k127_5317657_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000005927 231.0
EH2_k127_5317657_7 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000002784 198.0
EH2_k127_5317657_8 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000001944 186.0
EH2_k127_5318173_0 Uncharacterized protein family (UPF0051) K07033 - - 1.824e-201 634.0
EH2_k127_5318173_1 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 484.0
EH2_k127_5318173_2 FeS assembly ATPase SUFC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005002 263.0
EH2_k127_5318173_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002595 254.0
EH2_k127_5323228_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 371.0
EH2_k127_5323228_1 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002138 248.0
EH2_k127_5323228_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000002266 156.0
EH2_k127_5323228_3 - K09143 - - 0.00000000000000000000000000000000008948 137.0
EH2_k127_5323228_4 - - - - 0.0000000000000000000001302 105.0
EH2_k127_5339691_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 479.0
EH2_k127_5339691_1 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000004995 214.0
EH2_k127_5339691_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000006402 164.0
EH2_k127_5339691_3 YGGT family K02221 - - 0.00000000000000000000000000000000007546 135.0
EH2_k127_5346343_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.805e-211 676.0
EH2_k127_5346343_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 289.0
EH2_k127_5346343_2 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 293.0
EH2_k127_5346343_3 homoserine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000008418 169.0
EH2_k127_5346343_4 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000001896 149.0
EH2_k127_5366370_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 355.0
EH2_k127_5366370_1 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 308.0
EH2_k127_5366370_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001417 253.0
EH2_k127_5370456_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 452.0
EH2_k127_5370456_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 371.0
EH2_k127_5370456_2 electron transfer activity K03615 - - 0.00000000000000000000000000000000000000000000000000000000001254 213.0
EH2_k127_5384805_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 453.0
EH2_k127_5384805_1 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 362.0
EH2_k127_5384805_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 303.0
EH2_k127_5384805_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000007035 81.0
EH2_k127_5384805_4 Bacterial PH domain - - - 0.00000000000001845 79.0
EH2_k127_5384805_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000002738 50.0
EH2_k127_5384805_7 - K07803 - - 0.000004674 53.0
EH2_k127_5386144_0 Heat shock 70 kDa protein K04043 - - 0.0 1007.0
EH2_k127_5386144_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 4.306e-194 614.0
EH2_k127_5386144_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 558.0
EH2_k127_5386144_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 426.0
EH2_k127_5386144_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 326.0
EH2_k127_5386144_5 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000001762 176.0
EH2_k127_5386144_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000006191 170.0
EH2_k127_5386144_7 Belongs to the peptidase C1 family - - - 0.0000009537 55.0
EH2_k127_5419016_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 8.254e-292 921.0
EH2_k127_5419016_1 nucleotide catabolic process - - - 0.0000000000000000000000000000000000000000000000002903 179.0
EH2_k127_5419016_2 - - - - 0.00000004992 58.0
EH2_k127_5444133_0 ATPases associated with a variety of cellular activities - - - 1.125e-201 637.0
EH2_k127_5444133_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 475.0
EH2_k127_5444133_10 PFAM Sporulation related domain - - - 0.0006882 51.0
EH2_k127_5444133_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
EH2_k127_5444133_3 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000003116 230.0
EH2_k127_5444133_4 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000003212 159.0
EH2_k127_5444133_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000054 108.0
EH2_k127_5444133_6 nucleotidyltransferase activity - - - 0.000000000000000000000131 102.0
EH2_k127_5444133_7 peptidyl-tyrosine sulfation - - - 0.0000000000001964 79.0
EH2_k127_5444133_8 TonB C terminal - - - 0.000000000009533 74.0
EH2_k127_5444133_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000001591 65.0
EH2_k127_5449524_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 374.0
EH2_k127_5449524_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 319.0
EH2_k127_5477260_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000005394 246.0
EH2_k127_5477260_1 Pfam Response regulator receiver K07658 - - 0.0000000000000000000000000000000000005331 143.0
EH2_k127_5477260_2 - - - - 0.000000005262 59.0
EH2_k127_5520_0 Surface antigen K07277 - - 4.61e-263 831.0
EH2_k127_5520_1 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 3.213e-224 702.0
EH2_k127_5520_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000007072 221.0
EH2_k127_5520_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000001702 185.0
EH2_k127_5520_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000004701 173.0
EH2_k127_5520_13 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.0000000000000000000000000000000000000000000002178 169.0
EH2_k127_5520_14 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000002346 173.0
EH2_k127_5520_15 metal cluster binding K06940 - - 0.000000000000000000000000000000000000165 149.0
EH2_k127_5520_16 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000138 107.0
EH2_k127_5520_17 Dissimilatory sulfite reductase D (DsrD) - - - 0.00000000000000004861 83.0
EH2_k127_5520_18 Regulatory protein, FmdB family - - - 0.000000000000007102 77.0
EH2_k127_5520_2 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 8.126e-197 619.0
EH2_k127_5520_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 516.0
EH2_k127_5520_4 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 435.0
EH2_k127_5520_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 417.0
EH2_k127_5520_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 390.0
EH2_k127_5520_7 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005865 279.0
EH2_k127_5520_8 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000002512 242.0
EH2_k127_5520_9 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
EH2_k127_5536005_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 478.0
EH2_k127_5536005_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 427.0
EH2_k127_5536005_2 - - - - 0.0000000000000000004124 99.0
EH2_k127_5539769_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 4.339e-207 671.0
EH2_k127_5549345_0 response to UV K13281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 333.0
EH2_k127_5549345_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000005854 233.0
EH2_k127_5549345_2 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000005993 175.0
EH2_k127_5549345_3 glyoxalase III activity - - - 0.000000000000000000000000000000000000002972 149.0
EH2_k127_5549345_4 Methyltransferase domain - - - 0.00000000000000000005537 100.0
EH2_k127_5549345_5 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.0000000000001565 72.0
EH2_k127_5549345_6 Pfam:Pyridox_oxidase - - - 0.00000221 49.0
EH2_k127_5567283_0 Phosphoglycerate kinase K00927 - 2.7.2.3 2.788e-203 639.0
EH2_k127_5567283_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 502.0
EH2_k127_5567283_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 502.0
EH2_k127_5567283_3 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 482.0
EH2_k127_5567283_4 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 372.0
EH2_k127_5567283_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000001319 230.0
EH2_k127_5567283_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000009493 107.0
EH2_k127_5567283_7 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000002062 89.0
EH2_k127_5567283_8 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002684 73.0
EH2_k127_5602693_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.596e-201 632.0
EH2_k127_5602693_1 PKD domain containing protein K01179,K07004,K13277,K20276,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 0.0000000000000000000000008412 117.0
EH2_k127_5602693_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000163 105.0
EH2_k127_5602693_3 nucleotidyltransferase activity - - - 0.00000000000000001279 87.0
EH2_k127_5605923_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 476.0
EH2_k127_5605923_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008873 277.0
EH2_k127_5605923_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.00000000000000000000001431 106.0
EH2_k127_5605923_4 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000006353 64.0
EH2_k127_5605923_5 - - - - 0.000001529 50.0
EH2_k127_5605923_6 - - - - 0.000154 49.0
EH2_k127_5625771_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 6.014e-196 624.0
EH2_k127_5625771_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 605.0
EH2_k127_5625771_10 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000002051 92.0
EH2_k127_5625771_2 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 406.0
EH2_k127_5625771_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 403.0
EH2_k127_5625771_4 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 372.0
EH2_k127_5625771_5 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002064 251.0
EH2_k127_5625771_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000006698 198.0
EH2_k127_5625771_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000002166 197.0
EH2_k127_5625771_8 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000007074 172.0
EH2_k127_5625771_9 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000006093 121.0
EH2_k127_5637688_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.284e-242 760.0
EH2_k127_5637688_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 424.0
EH2_k127_5637688_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000002392 129.0
EH2_k127_5637688_12 Uncharacterised protein family (UPF0158) - - - 0.000000000000005524 83.0
EH2_k127_5637688_13 to Saccharomyces cerevisiae TOM71 (YHR117W) and TOM70 (YNL121C) K17768 GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005742,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0017038,GO:0019867,GO:0030150,GO:0030943,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044743,GO:0045039,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:0090151,GO:0098573,GO:0098588,GO:0098796,GO:0098798,GO:0098799,GO:0098805,GO:1990542 - 0.00004033 56.0
EH2_k127_5637688_2 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 362.0
EH2_k127_5637688_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 304.0
EH2_k127_5637688_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000005517 197.0
EH2_k127_5637688_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000104 165.0
EH2_k127_5637688_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000004016 153.0
EH2_k127_5637688_7 Protein of unknown function (DUF1284) K09706 - - 0.000000000000000000000000000000000001091 142.0
EH2_k127_5637688_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000001376 143.0
EH2_k127_5637688_9 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000004287 141.0
EH2_k127_5679878_0 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000003612 265.0
EH2_k127_5679878_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000001274 196.0
EH2_k127_5679878_2 - - - - 0.000000008527 68.0
EH2_k127_5679878_3 cAMP biosynthetic process - - - 0.00002669 57.0
EH2_k127_5705896_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009144 280.0
EH2_k127_5705896_1 PFAM Nitroreductase - - - 0.00000000000000001801 83.0
EH2_k127_5727716_0 Protein of unknown function, DUF255 K06888 - - 2.736e-257 809.0
EH2_k127_5727716_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 405.0
EH2_k127_5727716_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000002988 261.0
EH2_k127_5727716_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000126 254.0
EH2_k127_5727716_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000001314 194.0
EH2_k127_5727716_5 DsrC like protein K11179 - - 0.000000000000000000000000000000009568 130.0
EH2_k127_5727716_6 PFAM Nitroreductase - - - 0.000007112 48.0
EH2_k127_5803219_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.899e-213 672.0
EH2_k127_5803219_1 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000646 185.0
EH2_k127_5803219_2 Domain of unknown function (DUF3842) - - - 0.00000000000000000000000000000000000000000000000005972 182.0
EH2_k127_5803219_3 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000000000001297 161.0
EH2_k127_5803219_4 Predicted RNA-binding protein - - - 0.00000000000000000000001711 100.0
EH2_k127_5803219_5 electron transfer activity K05337,K17247 - - 0.0000000000000000000001739 98.0
EH2_k127_5803219_6 Protein of unknown function (DUF2934) - - - 0.00000000001369 66.0
EH2_k127_586099_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.695e-248 771.0
EH2_k127_586099_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000007484 177.0
EH2_k127_6008912_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.471e-208 657.0
EH2_k127_6008912_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 519.0
EH2_k127_6008912_10 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000001031 180.0
EH2_k127_6008912_11 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000001719 183.0
EH2_k127_6008912_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000008154 172.0
EH2_k127_6008912_13 tigr00255 - - - 0.00000000000000000000000000001262 123.0
EH2_k127_6008912_14 Domain of unknown function (DUF370) K09777 - - 0.00000000000000000000000000032 115.0
EH2_k127_6008912_15 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000014 116.0
EH2_k127_6008912_16 Tetratricopeptide repeat - - - 0.0000000000000000006059 97.0
EH2_k127_6008912_2 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 507.0
EH2_k127_6008912_3 Sodium:neurotransmitter symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 499.0
EH2_k127_6008912_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 453.0
EH2_k127_6008912_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 383.0
EH2_k127_6008912_6 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 300.0
EH2_k127_6008912_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000002856 237.0
EH2_k127_6008912_8 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000002822 224.0
EH2_k127_6008912_9 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000001238 222.0
EH2_k127_6177967_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 361.0
EH2_k127_6177967_1 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000002715 162.0
EH2_k127_6181971_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
EH2_k127_6181971_1 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000004313 227.0
EH2_k127_6199285_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 326.0
EH2_k127_6199285_1 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000001649 247.0
EH2_k127_6199285_2 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000001022 237.0
EH2_k127_6199285_4 Protein of unknown function (DUF2283) - - - 0.000000000000000009543 84.0
EH2_k127_6232241_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002805 280.0
EH2_k127_6232241_1 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000001269 180.0
EH2_k127_6232241_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000003371 155.0
EH2_k127_6232241_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000001744 64.0
EH2_k127_6238374_0 - K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 422.0
EH2_k127_6238374_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000002405 99.0
EH2_k127_6267757_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.379e-264 818.0
EH2_k127_6267757_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 455.0
EH2_k127_6267757_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 349.0
EH2_k127_6267757_3 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000002222 184.0
EH2_k127_6267757_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000006641 149.0
EH2_k127_6280334_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.371e-213 668.0
EH2_k127_6280334_1 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 589.0
EH2_k127_6280334_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 296.0
EH2_k127_6280334_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000943 267.0
EH2_k127_6280334_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000001047 222.0
EH2_k127_6280334_5 General secretory system II protein E domain protein - - - 0.000000000000000000000000000000239 134.0
EH2_k127_6280334_6 Large extracellular alpha-helical protein - - - 0.0000000000000000000001145 109.0
EH2_k127_6280334_7 cellulase activity K12287 - - 0.00000000003931 74.0
EH2_k127_6298653_0 Protein of unknown function DUF86 - - - 0.0000000000000000000001027 103.0
EH2_k127_6298653_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000003483 73.0
EH2_k127_6298653_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000009721 65.0
EH2_k127_6298653_3 - - - - 0.0000000001173 66.0
EH2_k127_6298653_4 Nucleotidyltransferase domain K07076 - - 0.0000000004025 65.0
EH2_k127_6298653_5 AbrB family - - - 0.0000001519 55.0
EH2_k127_6298730_0 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 545.0
EH2_k127_6298730_1 Kazal type serine protease inhibitors - - - 0.000008339 49.0
EH2_k127_6303119_0 Belongs to the peptidase S16 family - - - 5.037e-209 671.0
EH2_k127_6303119_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 289.0
EH2_k127_6303119_2 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000008752 181.0
EH2_k127_6330064_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1506.0
EH2_k127_6330064_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 315.0
EH2_k127_6330064_2 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000004348 238.0
EH2_k127_6330064_3 Radical SAM K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000068 229.0
EH2_k127_6330064_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000009907 208.0
EH2_k127_6330064_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000002661 195.0
EH2_k127_6330064_6 PFAM Radical SAM domain protein - - - 0.000000000002123 77.0
EH2_k127_6334519_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 434.0
EH2_k127_6334519_1 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 406.0
EH2_k127_6334519_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 396.0
EH2_k127_6334519_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000006543 134.0
EH2_k127_6334519_4 Cell wall formation K00075 - 1.3.1.98 0.0001028 45.0
EH2_k127_6335581_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 315.0
EH2_k127_6347527_0 Aminotransferase class I and II K14261 - - 2.451e-209 655.0
EH2_k127_6347527_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.434e-194 613.0
EH2_k127_6347527_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 459.0
EH2_k127_6347527_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 356.0
EH2_k127_6347527_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 324.0
EH2_k127_6347527_5 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000244 176.0
EH2_k127_6347527_6 ORF6N domain - - - 0.0000000000000000000000000000000000000000002487 162.0
EH2_k127_6347527_7 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000000000000009446 155.0
EH2_k127_6347527_8 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000105 154.0
EH2_k127_6352978_0 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 373.0
EH2_k127_6352978_1 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000009475 224.0
EH2_k127_6381607_0 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 474.0
EH2_k127_6381607_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 345.0
EH2_k127_6381607_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000002966 137.0
EH2_k127_6382670_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 7.924e-216 678.0
EH2_k127_6382670_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000001493 214.0
EH2_k127_6382670_2 cytochrome c nitrate reductase, small subunit K15876 - - 0.000000000000000000000000000000000000000000000000000006955 193.0
EH2_k127_6389821_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 372.0
EH2_k127_6389821_1 PFAM response regulator receiver - - - 0.0000000000000000000000000000000002714 139.0
EH2_k127_6391035_0 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000000000004232 189.0
EH2_k127_6391035_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000001694 67.0
EH2_k127_6440788_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.362e-252 784.0
EH2_k127_6440788_1 Sugar (and other) transporter K03446 - - 2.716e-216 681.0
EH2_k127_6440788_10 Plasmid stabilization system K19092 GO:0002790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030255,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0043684,GO:0044097,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0097159,GO:1901363 - 0.000000000000000000000000006602 113.0
EH2_k127_6440788_12 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000101 92.0
EH2_k127_6440788_13 Protein of unknown function (DUF1016) - - - 0.00000000000000005834 83.0
EH2_k127_6440788_14 Bacterial antitoxin of type II TA system, VapB - - - 0.00004516 48.0
EH2_k127_6440788_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 403.0
EH2_k127_6440788_3 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 382.0
EH2_k127_6440788_4 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 348.0
EH2_k127_6440788_5 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 294.0
EH2_k127_6440788_6 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003174 268.0
EH2_k127_6440788_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001462 250.0
EH2_k127_6440788_8 Protein of unknown function (DUF3024) - - - 0.000000000000000000000000000000000006379 139.0
EH2_k127_6440788_9 Large family of predicted nucleotide-binding domains - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000003399 119.0
EH2_k127_6462934_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 465.0
EH2_k127_6462934_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000001029 229.0
EH2_k127_6492707_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 355.0
EH2_k127_6492707_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000003139 199.0
EH2_k127_6492707_2 ABC-2 type transporter K01992,K09694 - - 0.0000000000000000000000000000000000000000000000000003068 186.0
EH2_k127_6544484_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 401.0
EH2_k127_6544484_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006109 277.0
EH2_k127_6544484_2 Putative regulatory protein - - - 0.00000002573 58.0
EH2_k127_663488_0 DNA photolyase K01669 - 4.1.99.3 1.092e-199 633.0
EH2_k127_663488_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 443.0
EH2_k127_663488_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 361.0
EH2_k127_663488_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 352.0
EH2_k127_663488_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003162 266.0
EH2_k127_663488_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000002182 233.0
EH2_k127_663488_6 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000673 171.0
EH2_k127_663488_7 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000007116 147.0
EH2_k127_663488_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000106 142.0
EH2_k127_663488_9 PFAM pyridoxamine 5-phosphate - - - 0.0000000000000585 72.0
EH2_k127_6638777_0 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 520.0
EH2_k127_6638777_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001075 252.0
EH2_k127_6638777_10 Protein of unknown function (DUF507) - - - 0.00000000000000000000000002271 111.0
EH2_k127_6638777_11 Protein of unknown function (DUF507) - - - 0.000000000000000000000001097 105.0
EH2_k127_6638777_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000003298 100.0
EH2_k127_6638777_13 - - - - 0.000000000000000000003314 96.0
EH2_k127_6638777_14 IMG reference gene - - - 0.00000000000000000002686 107.0
EH2_k127_6638777_15 - - - - 0.0000000000000007308 77.0
EH2_k127_6638777_16 PIN domain - - - 0.000000000000005467 81.0
EH2_k127_6638777_17 - - - - 0.00000000008138 63.0
EH2_k127_6638777_18 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.000000001687 72.0
EH2_k127_6638777_19 Bacterial antitoxin of type II TA system, VapB - - - 0.0000003161 54.0
EH2_k127_6638777_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000197 215.0
EH2_k127_6638777_20 Methyltransferase domain - - - 0.000002439 51.0
EH2_k127_6638777_21 - - - - 0.000004425 49.0
EH2_k127_6638777_3 PFAM Methyltransferase - - - 0.00000000000000000000000000000000000000000000000002302 183.0
EH2_k127_6638777_4 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000001906 168.0
EH2_k127_6638777_5 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000000000000000000941 149.0
EH2_k127_6638777_6 HNH nucleases - - - 0.000000000000000000000000000000000001777 140.0
EH2_k127_6638777_7 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000004073 113.0
EH2_k127_6638777_8 ORF located using Blastx - - - 0.000000000000000000000000004636 112.0
EH2_k127_6638777_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000001936 110.0
EH2_k127_667930_0 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008741 278.0
EH2_k127_667930_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000416 119.0
EH2_k127_667930_2 Protein of unknown function (DUF2905) - - - 0.00000000000000000000005661 99.0
EH2_k127_667930_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000004478 63.0
EH2_k127_6729601_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 441.0
EH2_k127_6729601_1 HEPN domain - - - 0.0000000000000000000000000464 112.0
EH2_k127_6729601_2 Nucleotidyltransferase domain - - - 0.000000000000007866 78.0
EH2_k127_6779542_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.219e-223 698.0
EH2_k127_6779542_1 Elongation factor SelB, winged helix K03833 - - 9.58e-215 683.0
EH2_k127_6779542_2 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 483.0
EH2_k127_6779542_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 420.0
EH2_k127_6779542_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 329.0
EH2_k127_6779542_5 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000001415 168.0
EH2_k127_6779542_6 Uncharacterized protein family UPF0016 - - - 0.0000017 50.0
EH2_k127_6824120_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 578.0
EH2_k127_6824120_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 364.0
EH2_k127_6824120_2 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000001195 238.0
EH2_k127_6824120_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000008402 178.0
EH2_k127_6824120_4 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000005575 143.0
EH2_k127_6827087_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.53e-281 873.0
EH2_k127_6827087_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 568.0
EH2_k127_6827087_10 Protein of unknown function DUF262 - - - 0.00000000000000000000000000000000000000002724 166.0
EH2_k127_6827087_11 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000289 156.0
EH2_k127_6827087_12 - - - - 0.000000000000000000005482 97.0
EH2_k127_6827087_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 490.0
EH2_k127_6827087_3 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 317.0
EH2_k127_6827087_4 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 312.0
EH2_k127_6827087_5 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001324 278.0
EH2_k127_6827087_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000252 274.0
EH2_k127_6827087_7 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000366 221.0
EH2_k127_6827087_8 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000121 206.0
EH2_k127_6827087_9 cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000000000000000000000000000000003027 174.0
EH2_k127_6831345_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.813e-239 748.0
EH2_k127_6831345_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.085e-231 730.0
EH2_k127_6831345_10 phosphorelay signal transduction system - - - 0.00000000000000000000000001974 117.0
EH2_k127_6831345_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.856e-229 716.0
EH2_k127_6831345_3 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 602.0
EH2_k127_6831345_4 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 505.0
EH2_k127_6831345_5 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 479.0
EH2_k127_6831345_6 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 374.0
EH2_k127_6831345_7 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 312.0
EH2_k127_6831345_8 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000636 274.0
EH2_k127_6831345_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002111 256.0
EH2_k127_6872119_0 sister chromatid segregation - - - 2.501e-200 638.0
EH2_k127_6872119_1 Flavodoxin - - - 1.207e-195 616.0
EH2_k127_6872119_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 578.0
EH2_k127_6872119_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000002216 266.0
EH2_k127_6872119_4 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000006992 151.0
EH2_k127_6934248_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 2.475e-260 812.0
EH2_k127_6934248_1 rubredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 302.0
EH2_k127_6955922_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.743e-234 735.0
EH2_k127_6955922_1 metallochaperone-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 613.0
EH2_k127_6955922_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 296.0
EH2_k127_6955922_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
EH2_k127_6955922_4 aminopeptidase N - - - 0.000000000000000000000000000000000000009153 151.0
EH2_k127_6955922_5 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000003039 98.0
EH2_k127_6966914_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.293e-217 678.0
EH2_k127_6966914_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000408 189.0
EH2_k127_6966914_2 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000004797 105.0
EH2_k127_6966914_3 PIN domain - - - 0.000000000000000000000007932 105.0
EH2_k127_6966914_4 Stringent starvation protein B K09985 - - 0.000000000000001032 83.0
EH2_k127_6966914_5 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000222 77.0
EH2_k127_6966914_6 - - - - 0.00000000000009308 76.0
EH2_k127_6991350_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 450.0
EH2_k127_6991350_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 452.0
EH2_k127_6991350_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 361.0
EH2_k127_6991350_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 351.0
EH2_k127_6991350_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002145 218.0
EH2_k127_6991350_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000009704 193.0
EH2_k127_7216677_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1021.0
EH2_k127_7216677_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.807e-210 665.0
EH2_k127_7216677_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000002955 137.0
EH2_k127_7216677_11 - - - - 0.000000000000000000000000000000005882 132.0
EH2_k127_7216677_12 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000004603 124.0
EH2_k127_7216677_13 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000006272 123.0
EH2_k127_7216677_14 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.00000000000000000002507 94.0
EH2_k127_7216677_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000002832 89.0
EH2_k127_7216677_16 Cupin 2, conserved barrel - - - 0.000000000000008515 75.0
EH2_k127_7216677_17 Modulates RecA activity K03565 - - 0.00000001459 62.0
EH2_k127_7216677_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 505.0
EH2_k127_7216677_3 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 470.0
EH2_k127_7216677_4 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 330.0
EH2_k127_7216677_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 327.0
EH2_k127_7216677_6 PFAM Peptidase M11 gametolysin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 317.0
EH2_k127_7216677_7 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000000001958 199.0
EH2_k127_7216677_8 - - - - 0.00000000000000000000000000000000000000000004293 166.0
EH2_k127_7216677_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000475 158.0
EH2_k127_7253029_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 494.0
EH2_k127_7253029_1 K06861 lipopolysaccharide export system ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 286.0
EH2_k127_7253029_10 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000168 52.0
EH2_k127_7253029_11 Lipopolysaccharide-assembly, LptC-related - - - 0.0002177 51.0
EH2_k127_7253029_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008515 272.0
EH2_k127_7253029_3 viral genome integration into host DNA - - - 0.000000000000000000000000000000000000000000000000000000002337 205.0
EH2_k127_7253029_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000003834 194.0
EH2_k127_7253029_5 OstA-like protein K09774 - - 0.000000000000000000000000000000000000407 145.0
EH2_k127_7253029_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000001972 126.0
EH2_k127_7253029_7 - - - - 0.000000001277 61.0
EH2_k127_7253511_0 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006969 291.0
EH2_k127_7253511_1 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000004709 214.0
EH2_k127_7253511_2 - - - - 0.0000000000000771 76.0
EH2_k127_7253511_3 PhoQ Sensor - - - 0.0001442 49.0
EH2_k127_7254706_0 Histidine kinase K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003273 298.0
EH2_k127_7254706_1 HD domain - - - 0.0000000000000000000000000000000000000000000004522 171.0
EH2_k127_7254706_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000001699 164.0
EH2_k127_7275630_0 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 425.0
EH2_k127_7275630_1 arsenite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000007613 210.0
EH2_k127_7275630_2 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000005762 200.0
EH2_k127_7356727_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 399.0
EH2_k127_7356727_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 353.0
EH2_k127_7356727_2 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 297.0
EH2_k127_7356727_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000006029 115.0
EH2_k127_7356727_4 - - - - 0.00000000001368 70.0
EH2_k127_7390534_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 395.0
EH2_k127_7390534_1 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006087 260.0
EH2_k127_7390534_10 - - - - 0.00009889 48.0
EH2_k127_7390534_11 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0003133 43.0
EH2_k127_7390534_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003765 246.0
EH2_k127_7390534_3 competence protein - - - 0.000000000000000000000000000000000000000002967 165.0
EH2_k127_7390534_4 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000005845 152.0
EH2_k127_7390534_5 PIN domain K18828 - - 0.000000000000000000000000000000000505 134.0
EH2_k127_7390534_6 Type I restriction-modification system methyltransferase subunit - - - 0.00000000000000000000000000001591 122.0
EH2_k127_7390534_7 cell envelope organization K05807,K08309 - - 0.00000000000003513 81.0
EH2_k127_7390534_8 restriction endonuclease - - - 0.00000000002306 65.0
EH2_k127_7390534_9 - - - - 0.0000000001785 68.0
EH2_k127_7416907_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1018.0
EH2_k127_7416907_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.764e-290 914.0
EH2_k127_7416907_10 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000000001296 154.0
EH2_k127_7416907_11 - - - - 0.00000000000000388 82.0
EH2_k127_7416907_12 cell cycle K05589,K12065,K13052 - - 0.000000000000054 76.0
EH2_k127_7416907_13 phosphorelay signal transduction system K20919 - - 0.000000000001598 69.0
EH2_k127_7416907_14 PFAM Transposase DDE domain - - - 0.0000000134 59.0
EH2_k127_7416907_2 Glycosyl hydrolase family 57 - - - 6.71e-235 747.0
EH2_k127_7416907_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 480.0
EH2_k127_7416907_4 TrkA-N domain K03455,K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 362.0
EH2_k127_7416907_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 317.0
EH2_k127_7416907_6 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 266.0
EH2_k127_7416907_7 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000004824 195.0
EH2_k127_7416907_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000004417 190.0
EH2_k127_7416907_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000005885 168.0
EH2_k127_7445641_0 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 583.0
EH2_k127_7445641_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 580.0
EH2_k127_7445641_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 419.0
EH2_k127_7445641_3 PFAM Pentapeptide repeats (8 copies) - - - 0.000002813 54.0
EH2_k127_7477917_0 alanine dehydrogenase activity K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 427.0
EH2_k127_7477917_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000009506 226.0
EH2_k127_7477917_2 DUF218 domain - - - 0.000000000000000000000000000274 121.0
EH2_k127_7604042_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.361e-206 653.0
EH2_k127_7604042_1 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
EH2_k127_7604042_2 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.00000000001272 72.0
EH2_k127_760629_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.494e-270 848.0
EH2_k127_760629_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 4.216e-216 683.0
EH2_k127_760629_2 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 479.0
EH2_k127_760629_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 329.0
EH2_k127_760629_4 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000004732 176.0
EH2_k127_760629_5 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000001392 146.0
EH2_k127_760629_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000003847 139.0
EH2_k127_760629_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000003215 100.0
EH2_k127_7613573_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 550.0
EH2_k127_7613573_1 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 541.0
EH2_k127_7613573_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 504.0
EH2_k127_7613573_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 338.0
EH2_k127_7613573_4 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000002012 209.0
EH2_k127_7613573_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000005422 208.0
EH2_k127_7613573_7 Adenosine specific kinase K09129 - - 0.00000000000000002403 82.0
EH2_k127_7613573_8 DnaJ molecular chaperone homology domain - - - 0.000001944 60.0
EH2_k127_7613573_9 Tetratricopeptide repeat K09553 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0012505,GO:0031072,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051879,GO:0101031 - 0.0000317 56.0
EH2_k127_7626927_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.43e-203 653.0
EH2_k127_7626927_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 433.0
EH2_k127_7626927_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000002232 140.0
EH2_k127_7630354_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1722.0
EH2_k127_7630354_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.633e-283 875.0
EH2_k127_7630354_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 334.0
EH2_k127_7630354_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001507 254.0
EH2_k127_7630354_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000001521 211.0
EH2_k127_7630354_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000001843 201.0
EH2_k127_7630354_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000002642 141.0
EH2_k127_7630354_7 structural constituent of ribosome K02913 - - 0.00000000000000002456 81.0
EH2_k127_7630354_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000003505 70.0
EH2_k127_7630354_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000003174 66.0
EH2_k127_7630527_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.977e-215 674.0
EH2_k127_7630527_1 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 516.0
EH2_k127_7630527_10 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000001066 230.0
EH2_k127_7630527_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000363 214.0
EH2_k127_7630527_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000001288 213.0
EH2_k127_7630527_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000194 215.0
EH2_k127_7630527_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000009684 199.0
EH2_k127_7630527_15 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000004171 179.0
EH2_k127_7630527_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000005394 174.0
EH2_k127_7630527_17 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000003749 168.0
EH2_k127_7630527_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000929 166.0
EH2_k127_7630527_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001089 167.0
EH2_k127_7630527_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 395.0
EH2_k127_7630527_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000002283 161.0
EH2_k127_7630527_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000148 152.0
EH2_k127_7630527_22 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000007276 147.0
EH2_k127_7630527_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000001187 143.0
EH2_k127_7630527_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000415 128.0
EH2_k127_7630527_25 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000001792 124.0
EH2_k127_7630527_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000004636 112.0
EH2_k127_7630527_27 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006413 110.0
EH2_k127_7630527_28 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000007655 110.0
EH2_k127_7630527_29 Homeodomain-like domain - - - 0.000000000000000000000002434 109.0
EH2_k127_7630527_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 369.0
EH2_k127_7630527_30 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000002914 102.0
EH2_k127_7630527_31 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000128 74.0
EH2_k127_7630527_32 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002736 74.0
EH2_k127_7630527_33 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000003174 66.0
EH2_k127_7630527_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 324.0
EH2_k127_7630527_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
EH2_k127_7630527_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 285.0
EH2_k127_7630527_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 281.0
EH2_k127_7630527_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007572 272.0
EH2_k127_7630527_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000002114 237.0
EH2_k127_7647818_0 CHASE2 K01768 - 4.6.1.1 1.668e-263 831.0
EH2_k127_7647818_1 FecR protein - - - 5.482e-230 726.0
EH2_k127_7649774_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001656 272.0
EH2_k127_7649774_1 hmm pf01609 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005998 248.0
EH2_k127_7649774_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000003389 226.0
EH2_k127_7709774_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1225.0
EH2_k127_7709774_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 9.805e-266 831.0
EH2_k127_7709774_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 537.0
EH2_k127_7709774_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 449.0
EH2_k127_7709774_4 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 390.0
EH2_k127_7709774_5 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 332.0
EH2_k127_7709774_6 Alanine-zipper, major outer membrane lipoprotein - - - 0.00000000000006824 75.0
EH2_k127_7709774_7 Universal stress protein family - - - 0.00002588 55.0
EH2_k127_7724824_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1202.0
EH2_k127_7724824_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001389 291.0
EH2_k127_7724824_2 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000002323 230.0
EH2_k127_7724824_3 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000001501 215.0
EH2_k127_7724824_4 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000005666 186.0
EH2_k127_7756618_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 593.0
EH2_k127_7756618_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 414.0
EH2_k127_7756618_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 368.0
EH2_k127_7756618_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008822 265.0
EH2_k127_7756618_4 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000001932 184.0
EH2_k127_7756618_5 peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000003423 174.0
EH2_k127_7756618_6 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000000000000000002625 168.0
EH2_k127_7756618_7 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000000000298 158.0
EH2_k127_7756618_8 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000001802 126.0
EH2_k127_7776062_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 2.304e-212 676.0
EH2_k127_7776062_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 2.074e-202 644.0
EH2_k127_7776062_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 620.0
EH2_k127_7776062_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 345.0
EH2_k127_7776062_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002809 271.0
EH2_k127_7776062_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000002359 241.0
EH2_k127_7776062_6 Putative zinc-finger - - - 0.00000000000000000000000000000000000000009086 164.0
EH2_k127_7839977_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 597.0
EH2_k127_7839977_1 PFAM Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 552.0
EH2_k127_7839977_10 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000002024 143.0
EH2_k127_7839977_2 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 449.0
EH2_k127_7839977_3 PFAM NADH flavin oxidoreductase NADH oxidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 331.0
EH2_k127_7839977_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007881 268.0
EH2_k127_7839977_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001188 246.0
EH2_k127_7839977_6 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008249 251.0
EH2_k127_7839977_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002177 232.0
EH2_k127_7839977_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000004427 153.0
EH2_k127_7839977_9 RNA-binding protein containing a PIN domain K06962 - - 0.00000000000000000000000000000000000005414 148.0
EH2_k127_8028613_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 395.0
EH2_k127_8028613_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001643 278.0
EH2_k127_8028613_2 Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000006556 176.0
EH2_k127_84347_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 494.0
EH2_k127_84347_1 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.000666 50.0
EH2_k127_95598_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 405.0
EH2_k127_95598_1 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000000000000003298 205.0
EH2_k127_95598_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000035 195.0
EH2_k127_95598_3 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000000000000003569 190.0
EH2_k127_95598_4 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000001415 92.0