Overview

ID MAG01043
Name EH2_bin.21
Sample SMP0029
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus
Species
Assembly information
Completeness (%) 85.84
Contamination (%) 3.36
GC content (%) 62.0
N50 (bp) 8,014
Genome size (bp) 1,725,676

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1578

Gene name Description KEGG GOs EC E-value Score Sequence
EH2_k127_1069499_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000107 217.0
EH2_k127_1069499_1 Membrane-flanked domain-containing protein - - - 0.000000003212 66.0
EH2_k127_107127_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 590.0
EH2_k127_107127_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000006281 184.0
EH2_k127_1077446_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 300.0
EH2_k127_1077446_1 transcriptional regulator, ModE family K02019 - - 0.000000000000000000000411 99.0
EH2_k127_1077446_2 PFAM Methyltransferase domain - - - 0.00000000000001021 87.0
EH2_k127_108803_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 386.0
EH2_k127_108803_1 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 331.0
EH2_k127_108803_2 - - - - 0.0000000006108 70.0
EH2_k127_1089823_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 484.0
EH2_k127_1089823_1 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000001672 167.0
EH2_k127_1089823_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000001671 102.0
EH2_k127_1089823_3 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000006157 55.0
EH2_k127_1096531_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000001969 261.0
EH2_k127_1096531_1 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000001965 175.0
EH2_k127_1096531_2 Peptidase family M28 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000002298 178.0
EH2_k127_1096609_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.614e-290 923.0
EH2_k127_1096609_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 451.0
EH2_k127_1096609_2 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000009222 182.0
EH2_k127_1096609_3 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000002421 171.0
EH2_k127_1096609_4 COG0456 Acetyltransferases - - - 0.0000000000000000003338 94.0
EH2_k127_1100404_0 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 469.0
EH2_k127_1100404_1 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 392.0
EH2_k127_1100404_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000005553 258.0
EH2_k127_1100404_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000678 168.0
EH2_k127_1100404_4 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00000000001482 66.0
EH2_k127_1100404_5 Fe-S oxidoreductase - - - 0.00000001198 66.0
EH2_k127_1100404_6 Major facilitator superfamily K08161 - - 0.0001546 53.0
EH2_k127_1107456_0 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000000007506 174.0
EH2_k127_1107456_1 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000001956 95.0
EH2_k127_1107456_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000002182 73.0
EH2_k127_1107456_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000698 50.0
EH2_k127_110990_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 316.0
EH2_k127_110990_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000113 196.0
EH2_k127_110990_2 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000000000000000000000002951 169.0
EH2_k127_110990_3 SCP-2 sterol transfer family - - - 0.00000000000000000007224 93.0
EH2_k127_110990_4 peptidyl-tyrosine sulfation - - - 0.0003791 49.0
EH2_k127_1117752_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 454.0
EH2_k127_1117752_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 385.0
EH2_k127_1117752_2 TIGRFAM acetylornithine deacetylase or K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 376.0
EH2_k127_1117752_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000000000000007763 239.0
EH2_k127_1117752_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000871 164.0
EH2_k127_1117752_5 Protein of unknown function (DUF3198) - - - 0.000000006063 62.0
EH2_k127_1123641_0 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 269.0
EH2_k127_1123641_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000003 249.0
EH2_k127_1160771_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 558.0
EH2_k127_1160771_1 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 372.0
EH2_k127_1160771_2 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 350.0
EH2_k127_1160771_3 - - - - 0.00000000000000000000000000000000000000000000000000007591 199.0
EH2_k127_1160771_4 - - - - 0.000001066 61.0
EH2_k127_1219452_0 TIGR00268 family K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
EH2_k127_1219452_1 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000004541 254.0
EH2_k127_1219452_2 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000045 217.0
EH2_k127_1219452_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000002055 119.0
EH2_k127_1225798_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.874e-219 703.0
EH2_k127_1225798_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 514.0
EH2_k127_1225798_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 397.0
EH2_k127_1225798_3 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 312.0
EH2_k127_1225798_4 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000008743 94.0
EH2_k127_1225798_5 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000105 77.0
EH2_k127_1225798_6 - - - - 0.000000000001339 77.0
EH2_k127_1225798_7 COG1522 Transcriptional regulators - - - 0.00000000002077 76.0
EH2_k127_124076_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 515.0
EH2_k127_124076_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 389.0
EH2_k127_124076_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002145 269.0
EH2_k127_124076_3 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000009112 252.0
EH2_k127_124076_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000005698 216.0
EH2_k127_124076_5 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.0000000000000000000000000000005247 128.0
EH2_k127_124076_6 PFAM molybdopterin-guanine dinucleotide biosynthesis MobB region K03753 - - 0.000000000000000000000000007117 119.0
EH2_k127_124076_7 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.00000000000000000000001881 104.0
EH2_k127_124076_8 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.0000007675 54.0
EH2_k127_125502_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 319.0
EH2_k127_125502_1 ABC-2 family transporter protein K01992 - - 0.00000002884 64.0
EH2_k127_1266208_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 7.27e-214 677.0
EH2_k127_1266208_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 379.0
EH2_k127_1266208_10 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000008295 190.0
EH2_k127_1266208_11 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000004992 184.0
EH2_k127_1266208_12 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000088 152.0
EH2_k127_1266208_13 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000002417 148.0
EH2_k127_1266208_14 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000003984 135.0
EH2_k127_1266208_15 rubredoxin - - - 0.000000000000000000001026 95.0
EH2_k127_1266208_16 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000001248 96.0
EH2_k127_1266208_17 Acetyltransferase (GNAT) domain - - - 0.000000000000007218 80.0
EH2_k127_1266208_18 - - - - 0.00000000000006469 80.0
EH2_k127_1266208_19 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000000003659 79.0
EH2_k127_1266208_2 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 321.0
EH2_k127_1266208_20 succinate dehydrogenase activity K00242,K00246 - - 0.0000000001763 67.0
EH2_k127_1266208_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 312.0
EH2_k127_1266208_4 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 291.0
EH2_k127_1266208_5 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000009176 259.0
EH2_k127_1266208_6 COG COG0714 MoxR-like ATPases General function prediction only - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005092 276.0
EH2_k127_1266208_7 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
EH2_k127_1266208_8 with different specificities (related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000001476 213.0
EH2_k127_1266208_9 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000003257 200.0
EH2_k127_1282066_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 618.0
EH2_k127_1282066_1 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008859 250.0
EH2_k127_1282066_2 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000001524 87.0
EH2_k127_1282066_3 Band 7 protein K07192 - - 0.00000000004808 72.0
EH2_k127_1300435_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 461.0
EH2_k127_1300435_1 oligoendopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 321.0
EH2_k127_1306810_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008109 279.0
EH2_k127_1306810_1 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
EH2_k127_1306810_2 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000004504 213.0
EH2_k127_1306810_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000417 135.0
EH2_k127_1306810_4 - - - - 0.00000000000000000000000000009963 128.0
EH2_k127_1306810_5 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000002156 95.0
EH2_k127_1306824_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 280.0
EH2_k127_1315690_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 519.0
EH2_k127_1315690_1 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 364.0
EH2_k127_1315690_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000002429 57.0
EH2_k127_1351447_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 420.0
EH2_k127_1351447_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 366.0
EH2_k127_1351447_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000007215 179.0
EH2_k127_1351447_3 CAAX protease self-immunity - - - 0.00000000000000000000000000003057 132.0
EH2_k127_1351447_4 RNA binding K09736 - - 0.00000000000000000000003534 103.0
EH2_k127_1351447_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000001594 59.0
EH2_k127_1405065_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 347.0
EH2_k127_1405065_1 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 303.0
EH2_k127_1405065_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001104 248.0
EH2_k127_1405065_3 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000153 236.0
EH2_k127_1405065_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000001095 64.0
EH2_k127_1405065_5 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000002553 63.0
EH2_k127_1438717_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 497.0
EH2_k127_1438717_1 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 324.0
EH2_k127_1438717_10 - - - - 0.000000000000000000000000000000000008466 142.0
EH2_k127_1438717_11 Receptor family ligand binding region K01999 - - 0.000000000000000002914 98.0
EH2_k127_1438717_12 Clostripain family - - - 0.000000000000002771 89.0
EH2_k127_1438717_13 Thioredoxin K03672 - 1.8.1.8 0.00000162 59.0
EH2_k127_1438717_14 transcriptional - - - 0.000003462 56.0
EH2_k127_1438717_15 Protein of unknown function (DUF3795) - - - 0.0008114 50.0
EH2_k127_1438717_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 295.0
EH2_k127_1438717_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001258 283.0
EH2_k127_1438717_4 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000496 297.0
EH2_k127_1438717_5 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000002621 186.0
EH2_k127_1438717_6 - - - - 0.00000000000000000000000000000000000000000000001658 178.0
EH2_k127_1438717_7 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000005605 181.0
EH2_k127_1438717_8 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000001862 163.0
EH2_k127_1438717_9 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000004039 157.0
EH2_k127_1442420_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 5.274e-200 634.0
EH2_k127_1442420_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 363.0
EH2_k127_1442420_2 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000000000000000000000003417 170.0
EH2_k127_1442420_3 Pfam:DUF552 K09152 - - 0.000000000000000000000000001134 117.0
EH2_k127_1442420_4 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000096 80.0
EH2_k127_1442420_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000605 78.0
EH2_k127_1442420_6 virion core protein (lumpy skin disease virus) - - - 0.0004414 48.0
EH2_k127_1447872_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 8.778e-243 767.0
EH2_k127_1447872_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 7.538e-220 713.0
EH2_k127_1447872_10 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000007439 185.0
EH2_k127_1447872_11 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000001485 166.0
EH2_k127_1447872_12 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000001487 130.0
EH2_k127_1447872_13 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000004098 121.0
EH2_k127_1447872_14 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000003777 68.0
EH2_k127_1447872_2 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 4.588e-208 662.0
EH2_k127_1447872_3 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 502.0
EH2_k127_1447872_4 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 452.0
EH2_k127_1447872_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 364.0
EH2_k127_1447872_6 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 312.0
EH2_k127_1447872_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000006582 248.0
EH2_k127_1447872_8 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000008765 214.0
EH2_k127_1447872_9 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000003722 187.0
EH2_k127_1478588_0 dTDP-4-dehydrorhamnose reductase K00067,K01790 - 1.1.1.133,5.1.3.13 0.00000000000000000000000000000000000000000000000000000006411 213.0
EH2_k127_1478588_1 Glucose-1-phosphate thymidyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000002704 205.0
EH2_k127_1478588_2 DUF3160 - - - 0.0008836 48.0
EH2_k127_1500573_0 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000001444 213.0
EH2_k127_1500573_1 EamA-like transporter family - - - 0.000000000000000000000000000000000002807 150.0
EH2_k127_1500573_2 membrane - - - 0.0000000008055 66.0
EH2_k127_1500573_3 Circadian clock protein KaiC - - - 0.00000007237 64.0
EH2_k127_151584_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1025.0
EH2_k127_151584_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 417.0
EH2_k127_151584_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 389.0
EH2_k127_151584_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 312.0
EH2_k127_151584_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000005532 191.0
EH2_k127_151584_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000002289 175.0
EH2_k127_151584_6 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000002699 159.0
EH2_k127_151584_7 Belongs to the PDCD5 family K06875 - - 0.000000000000000000002399 99.0
EH2_k127_151584_8 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000003941 74.0
EH2_k127_151584_9 Protein of unknown function (DUF835) - - - 0.0007915 52.0
EH2_k127_1529340_0 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000007057 132.0
EH2_k127_1529340_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000003521 133.0
EH2_k127_1529340_2 acetyltransferase K00670,K03789 - 2.3.1.128,2.3.1.256 0.000008518 51.0
EH2_k127_1529340_3 Transcriptional regulator - - - 0.00004913 47.0
EH2_k127_1544569_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 303.0
EH2_k127_1544569_1 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 294.0
EH2_k127_1544569_2 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000531 133.0
EH2_k127_1544569_3 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001176 87.0
EH2_k127_1544569_4 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000003626 76.0
EH2_k127_1544569_5 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00001168 51.0
EH2_k127_1598331_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 399.0
EH2_k127_1598331_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003278 282.0
EH2_k127_1598331_2 acetyl-CoA hydrolase transferase - - - 0.00000000000000000000000000006646 120.0
EH2_k127_1598331_3 amino acid - - - 0.000000004435 63.0
EH2_k127_1660993_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 437.0
EH2_k127_1660993_1 Peptidase S8 and S53 subtilisin kexin sedolisin K01342,K14645 - 3.4.21.62 0.00000000000000000000000000000000000000000000000000000000000000000002466 258.0
EH2_k127_1660993_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000003381 185.0
EH2_k127_1660993_3 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000005965 141.0
EH2_k127_1660993_4 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.00000000000000000000001723 103.0
EH2_k127_1660993_5 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000001605 91.0
EH2_k127_1660993_6 domain protein - - - 0.0000136 56.0
EH2_k127_1660993_7 Double zinc ribbon - - - 0.00002276 56.0
EH2_k127_1733302_0 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 338.0
EH2_k127_1733302_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000008203 250.0
EH2_k127_1733302_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
EH2_k127_1733302_3 PIN domain of ribonuclease K07060 - - 0.000000000000000000008013 98.0
EH2_k127_1733302_4 Right handed beta helix region - - - 0.00000000000301 79.0
EH2_k127_1733302_5 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000001633 57.0
EH2_k127_1764275_0 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000003051 178.0
EH2_k127_1764275_1 Band 7 protein K07192 - - 0.000000000000000000000000000000001895 141.0
EH2_k127_1766323_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 357.0
EH2_k127_1766323_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000003457 181.0
EH2_k127_1766323_2 SPFH domain-Band 7 family - - - 0.0000003601 62.0
EH2_k127_1779937_0 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000002059 172.0
EH2_k127_1779937_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000003873 157.0
EH2_k127_1779937_2 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.00000000000000000000000000000000348 133.0
EH2_k127_1779937_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000002607 118.0
EH2_k127_1779937_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000008467 110.0
EH2_k127_1786205_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.081e-200 640.0
EH2_k127_1786205_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
EH2_k127_1786205_2 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006161 276.0
EH2_k127_1819535_0 PFAM TatD-related deoxyribonuclease K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 259.0
EH2_k127_1819535_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000002112 150.0
EH2_k127_1857685_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.491e-217 689.0
EH2_k127_1857685_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.0000000000000000000000000000000000000000000000000000008363 203.0
EH2_k127_1857685_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000000002887 178.0
EH2_k127_1857685_3 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000008527 138.0
EH2_k127_1857685_4 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000000001035 118.0
EH2_k127_1857685_5 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000007122 96.0
EH2_k127_1861964_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005924 278.0
EH2_k127_1861964_1 alkyl hydroperoxide reductase activity - - - 0.000000000000000000000000007883 118.0
EH2_k127_1861964_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000002099 103.0
EH2_k127_1861964_3 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000001028 84.0
EH2_k127_1917064_0 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 560.0
EH2_k127_1917064_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 432.0
EH2_k127_1917064_10 PFAM CBS domain - - - 0.000000000000183 77.0
EH2_k127_1917064_11 PFAM Acetyltransferase (GNAT) family - - - 0.0000000001419 72.0
EH2_k127_1917064_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 376.0
EH2_k127_1917064_3 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 368.0
EH2_k127_1917064_4 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 303.0
EH2_k127_1917064_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000164 215.0
EH2_k127_1917064_6 PFAM DoxX family protein K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000000009583 196.0
EH2_k127_1917064_7 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000001234 100.0
EH2_k127_1917064_8 peroxiredoxin activity - - - 0.0000000000000001153 81.0
EH2_k127_1917064_9 FR47-like protein K03790 - 2.3.1.128 0.00000000000005071 79.0
EH2_k127_1931635_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.586e-196 624.0
EH2_k127_1931635_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000002322 231.0
EH2_k127_1931635_2 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000000274 217.0
EH2_k127_1931635_3 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000005034 169.0
EH2_k127_1931635_4 Phenazine biosynthesis protein phzf family - - - 0.000000000000000000000000000000000000007418 156.0
EH2_k127_1931635_5 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000001647 132.0
EH2_k127_1931635_6 GAF domain - - - 0.00000000000111 83.0
EH2_k127_1931635_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000006233 74.0
EH2_k127_1931635_8 PFAM GAF domain - - - 0.000001384 63.0
EH2_k127_1954810_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 314.0
EH2_k127_1954810_1 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000006814 60.0
EH2_k127_1954810_2 Protein of unknown function (DUF3800) - - - 0.0000000924 61.0
EH2_k127_206388_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 2.203e-196 627.0
EH2_k127_206388_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004412 280.0
EH2_k127_206388_2 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005996 256.0
EH2_k127_206388_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000006489 192.0
EH2_k127_206388_4 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000002502 201.0
EH2_k127_206388_5 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0007236 47.0
EH2_k127_2096768_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 365.0
EH2_k127_2096768_1 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 331.0
EH2_k127_2096768_2 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008536 249.0
EH2_k127_2096768_3 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000000002586 169.0
EH2_k127_2096768_4 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000007351 154.0
EH2_k127_2096768_5 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000004486 91.0
EH2_k127_2096768_6 Protein of unknown function (DUF2797) - - - 0.000000000000001544 87.0
EH2_k127_2096768_7 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.0000001798 64.0
EH2_k127_2114289_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 563.0
EH2_k127_2114289_1 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000001286 177.0
EH2_k127_2114289_2 Fcf1 K07158 - - 0.00000000000000000000002374 104.0
EH2_k127_2128339_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 431.0
EH2_k127_2128339_1 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 378.0
EH2_k127_2128339_10 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.00000000000000000000000000000000000006449 154.0
EH2_k127_2128339_11 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000007953 123.0
EH2_k127_2128339_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000034 91.0
EH2_k127_2128339_13 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000006458 60.0
EH2_k127_2128339_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 361.0
EH2_k127_2128339_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 377.0
EH2_k127_2128339_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001636 263.0
EH2_k127_2128339_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000002511 246.0
EH2_k127_2128339_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000002531 229.0
EH2_k127_2128339_7 Mechanosensitive ion channel K03442,K05802,K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000166 234.0
EH2_k127_2128339_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000001813 218.0
EH2_k127_2128339_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000002296 193.0
EH2_k127_2144727_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000002989 206.0
EH2_k127_2144727_1 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000005843 206.0
EH2_k127_2144727_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000006609 174.0
EH2_k127_2144727_3 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000004392 115.0
EH2_k127_2145743_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1274.0
EH2_k127_2145743_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.12e-301 932.0
EH2_k127_2145743_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 419.0
EH2_k127_2145743_3 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000000000000000000006214 210.0
EH2_k127_2145743_4 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.000000000000000000000000000006067 122.0
EH2_k127_2145743_5 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.0000000000000000000002508 98.0
EH2_k127_2147263_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 472.0
EH2_k127_2147263_1 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 366.0
EH2_k127_2153008_0 Aminopeptidase Iap family-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 342.0
EH2_k127_2153008_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 327.0
EH2_k127_2153008_2 DNA polymerase alpha chain like domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000229 244.0
EH2_k127_2153008_3 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000003111 205.0
EH2_k127_2153008_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000008403 151.0
EH2_k127_2153008_5 Peptidase family M54 K06974 - - 0.0000000000000000000000000309 114.0
EH2_k127_2153008_6 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000001327 70.0
EH2_k127_2153008_7 - - - - 0.00000000005596 66.0
EH2_k127_2154468_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 610.0
EH2_k127_2154468_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007981 263.0
EH2_k127_2154468_2 - - - - 0.0001959 44.0
EH2_k127_2160062_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 318.0
EH2_k127_2160062_1 Phosphate uptake regulator, PhoU - - - 0.00000000000000000000000000000000000000000000000000000000001289 219.0
EH2_k127_2160062_2 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000281 121.0
EH2_k127_2160062_3 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000543 123.0
EH2_k127_2180528_0 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000007155 183.0
EH2_k127_2180528_1 PFAM Forkhead-associated protein - - - 0.00000000000000000000000486 116.0
EH2_k127_2180528_2 - K00960 - 2.7.7.6 0.00000000000000004601 81.0
EH2_k127_2184074_0 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 499.0
EH2_k127_2184074_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000000000003364 228.0
EH2_k127_2184074_2 - - - - 0.0000000003595 61.0
EH2_k127_2195134_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 316.0
EH2_k127_2195134_1 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 307.0
EH2_k127_2195134_2 M42 glutamyl aminopeptidase - - - 0.0000000000000000000001166 100.0
EH2_k127_2195134_3 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000005629 100.0
EH2_k127_2201578_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 328.0
EH2_k127_2201578_1 Archaeal holliday junction resolvase (hjc) - - - 0.000000000000000000000000000000000000000000000000005524 186.0
EH2_k127_2201578_2 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00003142 55.0
EH2_k127_2249213_0 Flavodoxin - - - 0.000000000000000000000000000000002944 133.0
EH2_k127_2249213_1 recombinase XerD K04763 - - 0.00000000000000000000008271 109.0
EH2_k127_2249213_2 acetyltransferase - - - 0.0000000000002398 81.0
EH2_k127_2249213_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000393 58.0
EH2_k127_2260646_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.128e-228 719.0
EH2_k127_2260646_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000005229 92.0
EH2_k127_2265279_0 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000004813 163.0
EH2_k127_2265279_1 RDD family - - - 0.0000000000000233 79.0
EH2_k127_2265279_2 Pfam:DUF1628 - - - 0.000002613 56.0
EH2_k127_2274592_0 Peptidase family S51 - - - 0.0000000000000000000000000000000000000000000000000000000000007291 218.0
EH2_k127_2274592_1 Transposase, IS605 OrfB family K07496 - - 0.00000000000000000000000000000008386 138.0
EH2_k127_2283032_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 422.0
EH2_k127_2283032_1 Protein of unknown function (DUF531) K09725 - - 0.00000000000000000000000000000000000000000000003001 174.0
EH2_k127_2340235_0 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000426 155.0
EH2_k127_2340235_1 membrane K08971 - - 0.000000000000000000000001308 118.0
EH2_k127_2369902_0 MCM OB domain K10726 - - 4.018e-203 651.0
EH2_k127_2369902_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 326.0
EH2_k127_2369902_2 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000001681 218.0
EH2_k127_2369902_3 NMD3 family K07562 - - 0.000000000000000000000000000000000000000000000000003896 194.0
EH2_k127_2369902_4 Belongs to the peptidase S8 family - - - 0.000000000000000001797 100.0
EH2_k127_2369902_5 Protein of unknown function (DUF424) K09148 - - 0.000000000000001337 85.0
EH2_k127_2369902_6 Outer membrane protein beta-barrel family - - - 0.00006973 55.0
EH2_k127_2371257_0 Heat shock 70 kDa protein K04043 - - 1.55e-270 851.0
EH2_k127_2371257_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 4.585e-224 705.0
EH2_k127_2371257_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000008309 147.0
EH2_k127_2371257_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000001838 115.0
EH2_k127_2371652_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 600.0
EH2_k127_2371652_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 336.0
EH2_k127_2371652_2 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001154 281.0
EH2_k127_2371652_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000007544 202.0
EH2_k127_2371652_4 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000473 117.0
EH2_k127_237189_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 519.0
EH2_k127_237189_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000211 291.0
EH2_k127_237189_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000001461 104.0
EH2_k127_2432977_0 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004337 240.0
EH2_k127_2432977_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.00000000000000000000000000000000000000000000000000000000583 206.0
EH2_k127_2432977_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000008417 183.0
EH2_k127_2432977_3 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000008666 179.0
EH2_k127_2432977_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000002378 156.0
EH2_k127_2432977_5 PRC-barrel domain - - - 0.000000000000000004216 87.0
EH2_k127_2435003_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 584.0
EH2_k127_2435003_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 426.0
EH2_k127_2435003_2 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000006537 196.0
EH2_k127_2435003_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000001439 180.0
EH2_k127_2435003_4 dTDP metabolic process K00943 - 2.7.4.9 0.0000000000000000000000000000000000001483 148.0
EH2_k127_2435003_5 Belongs to the UPF0292 family - - - 0.000000000000000005186 88.0
EH2_k127_2435003_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000001066 76.0
EH2_k127_2435003_7 Belongs to the UPF0235 family K09131 - - 0.000000000001793 72.0
EH2_k127_2435003_8 protein conserved in archaea K09723 - - 0.0000000005827 68.0
EH2_k127_2435003_9 COG1522 Transcriptional regulators - - - 0.000000941 56.0
EH2_k127_2492690_0 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 355.0
EH2_k127_2492690_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000007359 210.0
EH2_k127_2522391_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 330.0
EH2_k127_2522391_1 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004567 274.0
EH2_k127_2522391_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000001792 204.0
EH2_k127_2522391_3 Response regulator receiver domain K03413 - - 0.000000000000000000000002465 107.0
EH2_k127_2522391_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000001661 106.0
EH2_k127_2522391_5 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.0000000162 59.0
EH2_k127_2560439_0 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 345.0
EH2_k127_2560439_1 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 332.0
EH2_k127_2560439_2 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000000273 91.0
EH2_k127_2560439_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000009776 86.0
EH2_k127_2560439_4 Domain of unknown function (DUF749) - - - 0.00004694 49.0
EH2_k127_256980_0 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 442.0
EH2_k127_256980_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 437.0
EH2_k127_256980_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000001979 131.0
EH2_k127_256980_3 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.0000000000000000000001027 106.0
EH2_k127_256980_4 Pfam:DUF59 - - - 0.000000000000000000309 91.0
EH2_k127_256980_5 Sulfur transfer protein involved in thiamine biosynthesis K03154,K21947 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.8.1.15 0.0000005909 54.0
EH2_k127_2673361_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 315.0
EH2_k127_2673361_1 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000001808 181.0
EH2_k127_2673361_2 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000371 168.0
EH2_k127_2673361_3 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000000000000000777 143.0
EH2_k127_2685477_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004737 286.0
EH2_k127_2685477_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.000000000000000000000000000000000000297 145.0
EH2_k127_2685477_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000443 83.0
EH2_k127_2689949_0 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 317.0
EH2_k127_2689949_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 312.0
EH2_k127_2689949_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 291.0
EH2_k127_2689949_3 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000008098 218.0
EH2_k127_2689949_4 - - - - 0.0000000000000000000000000000000000000000002165 167.0
EH2_k127_2689949_5 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000001033 113.0
EH2_k127_2689949_6 Methyltransferase type 11 - - - 0.00000000000000000000001137 110.0
EH2_k127_2689949_7 Clostripain family - - - 0.00000000000000000000997 106.0
EH2_k127_2689949_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000005855 85.0
EH2_k127_2689949_9 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000001435 66.0
EH2_k127_2698889_0 Major facilitator Superfamily K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 361.0
EH2_k127_2698889_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 317.0
EH2_k127_2698889_2 Bacteriocin-protection protein - - - 0.00000000000000000000000000000000000000001464 160.0
EH2_k127_2698889_3 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000282 158.0
EH2_k127_2698889_4 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000000000000761 111.0
EH2_k127_270429_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 368.0
EH2_k127_270429_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 356.0
EH2_k127_270429_2 ICC-like phosphoesterases K06953 - - 0.000000000000000000000000000000000000000000000000000000001375 209.0
EH2_k127_270429_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000004736 181.0
EH2_k127_270429_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000009065 181.0
EH2_k127_270429_5 Uncharacterized ArCR, COG1888 K09732 - - 0.000000000000000000000000000001124 123.0
EH2_k127_270429_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.00000000000003479 76.0
EH2_k127_270429_7 FHA domain - - - 0.0001817 53.0
EH2_k127_2741969_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 592.0
EH2_k127_2741969_1 Uncharacterized protein family UPF0004 K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 319.0
EH2_k127_2741969_2 nitroreductase K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000005459 179.0
EH2_k127_2741969_3 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000004973 173.0
EH2_k127_2741969_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000000000000000000000005092 139.0
EH2_k127_2741969_5 EamA-like transporter family - - - 0.0000000000000000000000000001002 129.0
EH2_k127_2741969_6 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000005668 111.0
EH2_k127_2741969_7 - - - - 0.0000003215 55.0
EH2_k127_2760364_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 535.0
EH2_k127_2760364_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 524.0
EH2_k127_2760364_2 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 387.0
EH2_k127_2760364_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000001044 194.0
EH2_k127_2760364_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000005676 186.0
EH2_k127_2809558_0 TPR Domain containing protein - - - 0.000000000000000000000000000000000000000000000000000002322 215.0
EH2_k127_2809558_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000352 173.0
EH2_k127_2809558_2 Response regulator receiver domain - - - 0.00000000000000000000000003535 111.0
EH2_k127_2809558_3 DNA-binding transcription factor activity K18297 - - 0.000000000000000004056 95.0
EH2_k127_2809558_4 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000003678 66.0
EH2_k127_2869023_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 448.0
EH2_k127_2869023_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000009428 106.0
EH2_k127_2869023_2 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000004564 87.0
EH2_k127_2869023_3 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000007807 69.0
EH2_k127_2872525_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 609.0
EH2_k127_2872525_1 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 407.0
EH2_k127_2872525_10 - - - - 0.0000000000000000102 92.0
EH2_k127_2872525_2 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 348.0
EH2_k127_2872525_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 305.0
EH2_k127_2872525_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001239 241.0
EH2_k127_2872525_5 PFAM Acetamidase Formamidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000173 220.0
EH2_k127_2872525_6 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000006485 205.0
EH2_k127_2872525_7 - - - - 0.0000000000000000000000000000000001294 141.0
EH2_k127_2872525_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000003023 116.0
EH2_k127_2872525_9 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000884 113.0
EH2_k127_2884584_0 helicase superfamily c-terminal domain K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 449.0
EH2_k127_2884584_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000000006225 197.0
EH2_k127_3023261_0 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000005194 190.0
EH2_k127_3023261_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000004423 69.0
EH2_k127_3050699_0 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 453.0
EH2_k127_3050699_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001952 298.0
EH2_k127_3050699_2 structural constituent of ribosome K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00001323 47.0
EH2_k127_306202_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 379.0
EH2_k127_306202_1 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 313.0
EH2_k127_306202_2 - - - - 0.00000000000000000000000000000003325 136.0
EH2_k127_306202_3 - - - - 0.000000000000000000000005645 106.0
EH2_k127_3077699_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 333.0
EH2_k127_3077699_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 306.0
EH2_k127_3077699_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007883 281.0
EH2_k127_3077699_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001448 201.0
EH2_k127_3077699_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000006439 107.0
EH2_k127_3077699_5 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000006691 65.0
EH2_k127_3086357_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1e-322 1002.0
EH2_k127_3086357_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 417.0
EH2_k127_3086357_2 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 292.0
EH2_k127_3086357_3 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003864 272.0
EH2_k127_3086357_4 - - - - 0.000000000000000000000001153 119.0
EH2_k127_3086357_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000306 102.0
EH2_k127_3086357_6 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000009666 63.0
EH2_k127_309099_0 PFAM thioesterase superfamily - - - 0.0000000000000000000000000005556 117.0
EH2_k127_309099_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000001775 97.0
EH2_k127_309099_2 - - - - 0.00000000001995 68.0
EH2_k127_3100641_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000004884 253.0
EH2_k127_3100641_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000008048 252.0
EH2_k127_3100641_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000003079 242.0
EH2_k127_3100641_3 ABC transporter, substratebinding protein K02035 - - 0.0000000000000000000000000008544 130.0
EH2_k127_3100641_4 B12 binding domain - - - 0.0000008588 53.0
EH2_k127_3100648_0 - - - - 0.000000000000000000000000000000000000000000000000002287 194.0
EH2_k127_3100648_1 - - - - 0.00000000000000000000000000000000000000000008034 173.0
EH2_k127_3100648_2 B12 binding domain - - - 0.0000003022 54.0
EH2_k127_3100648_3 - - - - 0.000001948 58.0
EH2_k127_3100648_4 YoaP-like - - - 0.0000339 55.0
EH2_k127_3113799_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 1.081e-286 899.0
EH2_k127_3113799_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 525.0
EH2_k127_3113799_10 Response regulator receiver domain K03413 - - 0.000000000000000000000002465 107.0
EH2_k127_3113799_11 oxidoreductase subunit delta K00171 - 1.2.7.1 0.00000000000000000000002514 111.0
EH2_k127_3113799_12 Acetyltransferase (GNAT) domain - - - 0.0000000000001347 81.0
EH2_k127_3113799_13 Tetratricopeptide repeat - - - 0.0000000000009392 79.0
EH2_k127_3113799_14 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000002296 74.0
EH2_k127_3113799_15 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.0000000118 59.0
EH2_k127_3113799_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 366.0
EH2_k127_3113799_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 322.0
EH2_k127_3113799_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 325.0
EH2_k127_3113799_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003595 278.0
EH2_k127_3113799_6 HisG, C-terminal domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007533 276.0
EH2_k127_3113799_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000002676 230.0
EH2_k127_3113799_8 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000001385 203.0
EH2_k127_3113799_9 PRC-barrel domain - - - 0.00000000000000000000000008708 108.0
EH2_k127_3157649_0 Clostripain family - - - 0.000000000000000000000002561 118.0
EH2_k127_317302_0 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000002466 237.0
EH2_k127_317302_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
EH2_k127_3190102_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 297.0
EH2_k127_3190102_1 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000002527 230.0
EH2_k127_3190102_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000001289 226.0
EH2_k127_3249864_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000001733 249.0
EH2_k127_3249864_1 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000007891 240.0
EH2_k127_3249864_2 - - - - 0.0000000000000000000000000000000000000004902 166.0
EH2_k127_3261815_0 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000002767 258.0
EH2_k127_3261815_1 - - - - 0.00000000000000000000000000000000000000004047 171.0
EH2_k127_3272400_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 526.0
EH2_k127_3272400_1 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 293.0
EH2_k127_3274247_0 MGS-like domain K00602,K01492 - 2.1.2.2,2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 453.0
EH2_k127_3274247_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000004783 159.0
EH2_k127_3274247_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000515 102.0
EH2_k127_3277299_0 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000007638 133.0
EH2_k127_3277299_1 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000035 94.0
EH2_k127_3277299_2 Transposase, IS605 OrfB family K07496 - - 0.000000671 59.0
EH2_k127_3283_0 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 513.0
EH2_k127_3283_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 320.0
EH2_k127_3283_2 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000008603 209.0
EH2_k127_3283_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000208 211.0
EH2_k127_3283_4 Fibronectin type 3 domain K20276 - - 0.00000000000000000000000000000007837 147.0
EH2_k127_3283_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000009966 136.0
EH2_k127_3283_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000001025 111.0
EH2_k127_3283_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000001188 83.0
EH2_k127_3298200_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 389.0
EH2_k127_3298200_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000002578 141.0
EH2_k127_3298200_2 4Fe-4S dicluster domain - - - 0.000000000000000000003901 99.0
EH2_k127_3307652_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 8.628e-243 770.0
EH2_k127_3307652_1 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001377 233.0
EH2_k127_3307652_2 Helix-turn-helix domain - - - 0.00000000001396 73.0
EH2_k127_3307652_3 Lrp/AsnC ligand binding domain - - - 0.0000008413 57.0
EH2_k127_3309958_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.164e-211 669.0
EH2_k127_3309958_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 323.0
EH2_k127_3309958_10 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000007792 149.0
EH2_k127_3309958_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000008353 150.0
EH2_k127_3309958_12 structural constituent of ribosome K02907 - - 0.000000000000000000000000000000000000001689 153.0
EH2_k127_3309958_13 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000006336 143.0
EH2_k127_3309958_14 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000002677 144.0
EH2_k127_3309958_15 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000003579 147.0
EH2_k127_3309958_16 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001032 107.0
EH2_k127_3309958_17 ribosomal protein S14 K02954 - - 0.000000000000000003941 91.0
EH2_k127_3309958_18 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000002908 73.0
EH2_k127_3309958_19 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.00000000002542 65.0
EH2_k127_3309958_2 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
EH2_k127_3309958_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000002181 219.0
EH2_k127_3309958_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002687 196.0
EH2_k127_3309958_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001465 192.0
EH2_k127_3309958_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000117 185.0
EH2_k127_3309958_7 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001219 186.0
EH2_k127_3309958_8 structural constituent of ribosome K02912 - - 0.0000000000000000000000000000000000000000005408 167.0
EH2_k127_3309958_9 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001641 171.0
EH2_k127_3337805_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 569.0
EH2_k127_3337805_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 446.0
EH2_k127_3337805_10 metallopeptidase activity K19668 - 3.2.1.91 0.000000000001166 83.0
EH2_k127_3337805_11 EamA-like transporter family - - - 0.000004515 58.0
EH2_k127_3337805_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000432 51.0
EH2_k127_3337805_2 Phosphohydrolase K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 276.0
EH2_k127_3337805_3 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000001835 231.0
EH2_k127_3337805_4 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000001069 211.0
EH2_k127_3337805_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000006775 211.0
EH2_k127_3337805_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000002546 187.0
EH2_k127_3337805_7 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000218 111.0
EH2_k127_3337805_8 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000002765 93.0
EH2_k127_3337805_9 Belongs to the UPF0248 family K09715 - - 0.00000000000000002155 84.0
EH2_k127_3361894_0 Proton-conducting membrane transporter K05565,K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 586.0
EH2_k127_3361894_1 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 407.0
EH2_k127_3361894_2 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 390.0
EH2_k127_3361894_3 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000002069 216.0
EH2_k127_3361894_4 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000001737 156.0
EH2_k127_3361894_5 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.0000000000000000000000000000001395 134.0
EH2_k127_3361894_6 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340,K22166 - 1.5.98.3,1.6.5.3 0.000000000000000000000000001665 119.0
EH2_k127_3361894_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000631 64.0
EH2_k127_343814_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000001208 243.0
EH2_k127_343814_1 COG0531 Amino acid transporters - - - 0.0000001054 55.0
EH2_k127_3476292_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 496.0
EH2_k127_3476292_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 435.0
EH2_k127_3476292_2 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002634 287.0
EH2_k127_3476292_3 Bacterial protein of unknown function (DUF885) - - - 0.00000000000006388 85.0
EH2_k127_3487919_0 COG0531 Amino acid transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 405.0
EH2_k127_3487919_1 NUDIX domain - - - 0.00000000000000000000000000000000005361 140.0
EH2_k127_3487919_2 nucleotide metabolic process - - - 0.00000000000000000000001098 109.0
EH2_k127_3487919_3 Zn-dependent exopeptidase K05994 - 3.4.11.10 0.00000000000000000001198 107.0
EH2_k127_3515217_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 419.0
EH2_k127_3528929_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 329.0
EH2_k127_3528929_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000002869 261.0
EH2_k127_3528929_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000005688 203.0
EH2_k127_3528929_3 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000005894 194.0
EH2_k127_3528929_4 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000003584 171.0
EH2_k127_3528929_5 Fibronectin type III domain - - - 0.0000000000008862 78.0
EH2_k127_3528929_6 chlorophyll binding - - - 0.00000000003531 73.0
EH2_k127_3528929_7 Clostripain family - - - 0.000000001984 70.0
EH2_k127_3528929_8 membrane-associated protein domain - - - 0.0000002068 60.0
EH2_k127_3568608_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000002789 193.0
EH2_k127_3568608_1 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.000000000000000000000000000000002236 141.0
EH2_k127_3568608_2 KaiC - - - 0.0000000000000000000000000000000155 137.0
EH2_k127_3575233_0 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001006 274.0
EH2_k127_3575233_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000004221 108.0
EH2_k127_3575233_2 PFAM ATP synthase subunit C K02124 - - 0.00000000001213 71.0
EH2_k127_3575233_3 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000003311 63.0
EH2_k127_3582244_0 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 537.0
EH2_k127_3582244_1 COG1994 Zn-dependent proteases - - - 0.0000000000000000000000000000000001262 141.0
EH2_k127_3582244_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000004832 71.0
EH2_k127_3582244_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0000166,GO:0003674,GO:0003824,GO:0004017,GO:0004550,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006165,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009141,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032261,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043173,GO:0044209,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 0.00008326 45.0
EH2_k127_3585704_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000001002 281.0
EH2_k127_3585704_1 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000007832 244.0
EH2_k127_3585704_2 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000003791 186.0
EH2_k127_3585704_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.000000000000000000000000000000000000001235 154.0
EH2_k127_3585704_4 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000000006091 146.0
EH2_k127_3585704_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000001258 108.0
EH2_k127_3666061_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 547.0
EH2_k127_3666061_1 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 521.0
EH2_k127_3666061_10 Belongs to the peptidase S8 family - - - 0.0000000008034 72.0
EH2_k127_3666061_11 transcription activator, effector binding - - - 0.00000006044 61.0
EH2_k127_3666061_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00007576 57.0
EH2_k127_3666061_13 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0004311 48.0
EH2_k127_3666061_2 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004955 280.0
EH2_k127_3666061_3 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000009577 212.0
EH2_k127_3666061_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000784 178.0
EH2_k127_3666061_5 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000002709 167.0
EH2_k127_3666061_6 TIGRFAM transposase, IS605 OrfB family - - - 0.000000000000000000000000000000000002024 153.0
EH2_k127_3666061_7 Transposase, IS605 OrfB family K07496 - - 0.00000000000000000000000000000000002715 150.0
EH2_k127_3666061_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.000000000000000009934 100.0
EH2_k127_3666061_9 membrane transporter protein K07090 - - 0.000000000000005286 85.0
EH2_k127_3699376_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 454.0
EH2_k127_3699376_1 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 328.0
EH2_k127_3699376_2 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000007573 265.0
EH2_k127_3699376_3 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000002395 218.0
EH2_k127_3699376_4 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000388 199.0
EH2_k127_3699376_5 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000000000000000000000000000005448 198.0
EH2_k127_3699376_6 TIGRFAM segregation and condensation protein B K06024 - - 0.0000000000000000000000000000000002087 142.0
EH2_k127_3699376_7 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000153 131.0
EH2_k127_3699376_8 snRNP Sm proteins K04796 - - 0.000000000000000000005429 93.0
EH2_k127_3762602_0 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 376.0
EH2_k127_3762602_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 322.0
EH2_k127_3762602_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 326.0
EH2_k127_3762602_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000009488 188.0
EH2_k127_3762602_4 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000005455 182.0
EH2_k127_3762602_5 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000007809 151.0
EH2_k127_3762602_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000184 76.0
EH2_k127_3762602_7 Archaeal holliday junction resolvase (hjc) - - - 0.0000001179 53.0
EH2_k127_380079_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 395.0
EH2_k127_380079_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 342.0
EH2_k127_380079_10 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.0000000000006844 68.0
EH2_k127_380079_11 Transcription factor Pcc1 K09741 - - 0.00000003057 58.0
EH2_k127_380079_12 - - - - 0.0005298 45.0
EH2_k127_380079_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 321.0
EH2_k127_380079_3 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 304.0
EH2_k127_380079_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 301.0
EH2_k127_380079_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001118 260.0
EH2_k127_380079_6 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 260.0
EH2_k127_380079_7 DHH family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002483 258.0
EH2_k127_380079_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000002874 93.0
EH2_k127_380079_9 binds to the 23S rRNA K02921 - - 0.0000000000000000004765 93.0
EH2_k127_3847201_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 381.0
EH2_k127_3847201_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 349.0
EH2_k127_3847201_2 PFAM UDP-N-acetylglucosamine 2-epimerase K01791 GO:0003674,GO:0003824,GO:0008761,GO:0016853,GO:0016854,GO:0016857 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 298.0
EH2_k127_3847201_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000001144 228.0
EH2_k127_3847201_4 PHP-associated - - - 0.0000000000000000000000000000000000000000001509 169.0
EH2_k127_3847201_5 - - - - 0.000000000000000004615 94.0
EH2_k127_3847201_6 Sugar (and other) transporter - - - 0.000008581 51.0
EH2_k127_3847201_7 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0009869 50.0
EH2_k127_3851472_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003807 282.0
EH2_k127_3851472_1 LemA family K03744 - - 0.0000000000000000000000000000000000003655 146.0
EH2_k127_3851472_2 TPM domain K06872 - - 0.0000000000000000000000002331 115.0
EH2_k127_3851472_3 hmm pf03415 K08587 - 3.4.22.8 0.000000000000000000000002991 116.0
EH2_k127_3851472_4 Clostripain family - - - 0.0000000000000000005295 100.0
EH2_k127_3852347_0 acetyl-CoA hydrolase transferase - - - 3.192e-196 624.0
EH2_k127_3852347_1 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000001145 192.0
EH2_k127_3859453_0 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 569.0
EH2_k127_3859453_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 525.0
EH2_k127_3859453_10 Clostripain family - - - 0.000000000000000000000000000000000003744 155.0
EH2_k127_3859453_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 461.0
EH2_k127_3859453_3 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 454.0
EH2_k127_3859453_4 Thioredoxin domain K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 366.0
EH2_k127_3859453_5 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 310.0
EH2_k127_3859453_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000002649 206.0
EH2_k127_3859453_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000002506 162.0
EH2_k127_3859453_8 - - - - 0.00000000000000000000000000000000000000001253 166.0
EH2_k127_3859453_9 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000002609 159.0
EH2_k127_3859467_0 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 568.0
EH2_k127_3923751_0 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 343.0
EH2_k127_3923751_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004815 267.0
EH2_k127_3923751_2 - - - - 0.0000000000000000000003298 100.0
EH2_k127_3923751_3 PAP2 superfamily - - - 0.000000000000000007764 94.0
EH2_k127_3923751_4 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000001237 72.0
EH2_k127_398008_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001623 168.0
EH2_k127_398008_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000003379 126.0
EH2_k127_398008_2 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000001453 91.0
EH2_k127_4011134_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 535.0
EH2_k127_4011134_1 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009589 276.0
EH2_k127_4011134_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K08323 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000001905 237.0
EH2_k127_4011134_3 Uridine phosphorylase - - - 0.000000000000000000000000000000000002622 148.0
EH2_k127_4011134_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000001721 118.0
EH2_k127_4011134_5 archaeal coiled-coil protein - - - 0.000000000000000000000007426 111.0
EH2_k127_4011134_6 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000002951 72.0
EH2_k127_4013675_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000004206 238.0
EH2_k127_4013675_1 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000000000003621 147.0
EH2_k127_4045328_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 593.0
EH2_k127_4045328_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 428.0
EH2_k127_4045328_10 cobalamin binding - - - 0.00000001487 56.0
EH2_k127_4045328_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 394.0
EH2_k127_4045328_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 338.0
EH2_k127_4045328_4 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 300.0
EH2_k127_4045328_5 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000002269 271.0
EH2_k127_4045328_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000002834 250.0
EH2_k127_4045328_7 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005784 255.0
EH2_k127_4045328_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002966 250.0
EH2_k127_4045328_9 transcription regulator activity - - - 0.0000000000000000000000000000000000000007883 152.0
EH2_k127_4063476_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.584e-220 706.0
EH2_k127_4063476_1 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000007 179.0
EH2_k127_4063476_2 Roadblock/LC7 domain K07131 - - 0.0000000009616 64.0
EH2_k127_4099142_0 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.0000000000000000000000000000000000000000000000000000000004953 215.0
EH2_k127_4099142_1 Universal stress protein family - - - 0.000000000000000000000000000000002014 134.0
EH2_k127_4099142_2 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000005972 88.0
EH2_k127_4099142_3 Protease prsW family - - - 0.000000000000001063 85.0
EH2_k127_4112059_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000005111 260.0
EH2_k127_4112059_1 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000001441 228.0
EH2_k127_4117158_0 KH, type 1, domain K07041 - - 2.847e-267 838.0
EH2_k127_4117158_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 379.0
EH2_k127_4117158_10 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.000000000001504 68.0
EH2_k127_4117158_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 352.0
EH2_k127_4117158_3 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 310.0
EH2_k127_4117158_4 PFAM peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005653 288.0
EH2_k127_4117158_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000004219 245.0
EH2_k127_4117158_6 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000001781 111.0
EH2_k127_4117158_7 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000000000002743 107.0
EH2_k127_4117158_8 - - - - 0.00000000000000000002116 106.0
EH2_k127_4117158_9 cheY-homologous receiver domain K03413 - - 0.0000000000000211 79.0
EH2_k127_4119808_0 Citrate transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 482.0
EH2_k127_4119808_1 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 360.0
EH2_k127_4119808_2 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003109 295.0
EH2_k127_4119808_3 amino acid - - - 0.00000000000003426 80.0
EH2_k127_4119808_4 Belongs to the peptidase S8 family K01361,K08652,K14647 GO:0005575,GO:0005576 3.4.21.110,3.4.21.96 0.0001366 57.0
EH2_k127_4124019_0 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 284.0
EH2_k127_4124019_1 4Fe-4S dicluster domain - - - 0.00000000000003779 76.0
EH2_k127_413291_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 342.0
EH2_k127_413291_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000007229 123.0
EH2_k127_413291_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000002344 101.0
EH2_k127_4178947_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 361.0
EH2_k127_4178947_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
EH2_k127_4178947_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001166 287.0
EH2_k127_4178947_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000002008 229.0
EH2_k127_4178947_4 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000002779 93.0
EH2_k127_4179519_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 489.0
EH2_k127_4179519_1 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000001876 166.0
EH2_k127_4179519_2 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000002124 169.0
EH2_k127_4179519_3 membrane-associated protein domain - - - 0.000002665 57.0
EH2_k127_4179776_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 1.143e-228 723.0
EH2_k127_4179776_1 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 407.0
EH2_k127_4179776_2 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
EH2_k127_4179776_3 Double zinc ribbon - - - 0.00000004878 65.0
EH2_k127_4179776_4 - - - - 0.0001846 44.0
EH2_k127_4225676_0 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 293.0
EH2_k127_4225676_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000007318 188.0
EH2_k127_4225676_2 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000002856 189.0
EH2_k127_4225676_3 - - - - 0.00000000000000000000000000001521 126.0
EH2_k127_4225676_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000203 108.0
EH2_k127_4228415_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 386.0
EH2_k127_4228415_1 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000001512 246.0
EH2_k127_4228415_2 Transcriptional regulator K22206 - - 0.000000000001169 72.0
EH2_k127_4228415_3 - - - - 0.00000001794 65.0
EH2_k127_4228415_4 - - - - 0.0000001139 62.0
EH2_k127_4228415_5 - - - - 0.00001018 56.0
EH2_k127_423428_0 DNA polymerase type-B family K02319 - 2.7.7.7 8.938e-264 837.0
EH2_k127_423428_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 523.0
EH2_k127_423428_10 Helix-hairpin-helix motif K07572 - - 0.000000000000000000001947 95.0
EH2_k127_423428_2 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 458.0
EH2_k127_423428_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 423.0
EH2_k127_423428_4 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 309.0
EH2_k127_423428_5 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000668 261.0
EH2_k127_423428_6 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000001411 256.0
EH2_k127_423428_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000001177 165.0
EH2_k127_423428_8 Transposase, IS605 OrfB family K07496 - - 0.000000000000000000000000000000002236 141.0
EH2_k127_423428_9 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000005874 104.0
EH2_k127_4235262_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 304.0
EH2_k127_4235262_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000007138 279.0
EH2_k127_4235262_2 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000001825 164.0
EH2_k127_4235262_3 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000008356 127.0
EH2_k127_4235262_4 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000000001475 94.0
EH2_k127_4235262_5 Response regulator receiver domain - - - 0.00000000000000001946 89.0
EH2_k127_4235262_6 DsrE/DsrF-like family K07236 - - 0.00000005296 59.0
EH2_k127_4235262_7 Thioredoxin domain - - - 0.000005708 55.0
EH2_k127_4235262_8 DsrH like protein K07237 - - 0.000314 48.0
EH2_k127_4245648_0 Double zinc ribbon - - - 0.0000000000000000000000000000000000001184 166.0
EH2_k127_4245648_1 Type II/IV secretion system protein K07332 - - 0.000316 44.0
EH2_k127_4252459_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 341.0
EH2_k127_4252459_1 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000008717 244.0
EH2_k127_4252459_2 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000005554 175.0
EH2_k127_4252459_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000002162 129.0
EH2_k127_4252459_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000003396 49.0
EH2_k127_4261524_0 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 423.0
EH2_k127_4261524_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 365.0
EH2_k127_4261524_2 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000003638 177.0
EH2_k127_4261524_3 Bacterio-opsin activator HTH K06930 - - 0.0000000003034 68.0
EH2_k127_4261524_4 Citrate transporter K14445 - - 0.0001348 45.0
EH2_k127_4292515_0 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 260.0
EH2_k127_4292515_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000003013 225.0
EH2_k127_4292515_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000607 164.0
EH2_k127_4295277_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 549.0
EH2_k127_4295277_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 472.0
EH2_k127_4295277_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0004512 44.0
EH2_k127_4311685_0 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 295.0
EH2_k127_4311685_1 Kelch motif - - - 0.0000000000000000000002813 112.0
EH2_k127_4322938_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 429.0
EH2_k127_4322938_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 346.0
EH2_k127_4322938_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001288 283.0
EH2_k127_4322938_3 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000006429 212.0
EH2_k127_4322938_4 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000000000000001407 160.0
EH2_k127_4322938_5 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000000001832 154.0
EH2_k127_4322938_6 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000001512 141.0
EH2_k127_4322938_7 Transcriptional regulator K07730 - - 0.00000000000001865 83.0
EH2_k127_4323394_0 domain protein K14194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 469.0
EH2_k127_4323394_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008441 278.0
EH2_k127_4323394_2 domain protein - - - 0.00000000000000000000000000000000000000001818 180.0
EH2_k127_4323394_3 Pro-kumamolisin, activation domain - - - 0.0000006577 57.0
EH2_k127_4323394_4 - - - - 0.00002013 55.0
EH2_k127_4331839_0 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000001394 248.0
EH2_k127_4331839_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000009914 185.0
EH2_k127_4331839_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299,K03281 - 3.4.17.19 0.000000000000000000000000000000000000000000006812 175.0
EH2_k127_4331839_3 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000002229 134.0
EH2_k127_4331839_4 SPFH domain / Band 7 family - - - 0.00000000000000000000000001822 119.0
EH2_k127_4331839_5 Histidine kinase - - - 0.000000000000000000003298 108.0
EH2_k127_4331839_6 response regulator, receiver - - - 0.00000000000000004602 94.0
EH2_k127_4331839_7 cobalamin binding - - - 0.00000001487 56.0
EH2_k127_4331839_8 SPFH domain / Band 7 family - - - 0.00001484 53.0
EH2_k127_4343396_0 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001985 292.0
EH2_k127_4343396_1 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000005288 221.0
EH2_k127_4343396_2 Radical SAM superfamily K06937 - - 0.00000000006435 64.0
EH2_k127_4374321_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 403.0
EH2_k127_4374321_1 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000000002987 160.0
EH2_k127_4378620_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 344.0
EH2_k127_4378620_1 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000003059 241.0
EH2_k127_4378620_2 PFAM 4-vinyl reductase, 4VR K07013 - - 0.00000000000000000000001333 105.0
EH2_k127_4378620_3 Roadblock LC7 family protein K07131 - - 0.0000000000000000006593 92.0
EH2_k127_4378620_4 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.0000000000000001585 80.0
EH2_k127_4384744_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 308.0
EH2_k127_4384744_1 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
EH2_k127_4384744_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000001154 194.0
EH2_k127_4384744_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000002254 108.0
EH2_k127_4384744_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000001883 102.0
EH2_k127_4384744_5 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00003588 48.0
EH2_k127_4428116_0 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
EH2_k127_4428116_1 Cephalosporin hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000001417 218.0
EH2_k127_4428116_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000002456 192.0
EH2_k127_4428116_3 CAAX protease self-immunity - - - 0.000000000000000004116 96.0
EH2_k127_4428116_4 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0001096 55.0
EH2_k127_4550773_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 8.237e-263 819.0
EH2_k127_4567765_0 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 299.0
EH2_k127_4567765_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000002093 235.0
EH2_k127_4616702_0 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 521.0
EH2_k127_4616702_1 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 330.0
EH2_k127_4616702_2 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006296 279.0
EH2_k127_4616702_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000001533 173.0
EH2_k127_4674686_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000002867 249.0
EH2_k127_4674686_1 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000003844 210.0
EH2_k127_4674686_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000006652 202.0
EH2_k127_4674686_3 Lysine-2,3-aminomutase K01843,K19814 - 5.4.3.2,5.4.3.9 0.0000000000000000000000000000000000000000000000009344 178.0
EH2_k127_4682697_0 AAA domain K01338 - 3.4.21.53 1.315e-199 634.0
EH2_k127_4682697_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 480.0
EH2_k127_4682697_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000003898 70.0
EH2_k127_4682697_11 GNAT family acetyltransferase - - - 0.000002591 56.0
EH2_k127_4682697_2 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 395.0
EH2_k127_4682697_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000001649 238.0
EH2_k127_4682697_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000002493 182.0
EH2_k127_4682697_5 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000001076 173.0
EH2_k127_4682697_6 Domains REC, HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000003967 176.0
EH2_k127_4682697_7 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000001397 166.0
EH2_k127_4682697_8 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000002165 106.0
EH2_k127_4682697_9 - - - - 0.000000000005204 77.0
EH2_k127_4708860_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 348.0
EH2_k127_4708860_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.000000000000000001168 95.0
EH2_k127_4754390_0 Uncharacterised ACR, YkgG family COG1556 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 314.0
EH2_k127_4754390_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000001342 143.0
EH2_k127_4769590_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1111.0
EH2_k127_4769590_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1085.0
EH2_k127_4769590_10 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000007653 196.0
EH2_k127_4769590_11 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000003295 120.0
EH2_k127_4769590_12 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000002642 66.0
EH2_k127_4769590_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.541e-262 827.0
EH2_k127_4769590_3 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 482.0
EH2_k127_4769590_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 451.0
EH2_k127_4769590_5 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 403.0
EH2_k127_4769590_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 338.0
EH2_k127_4769590_7 reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 297.0
EH2_k127_4769590_8 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
EH2_k127_4769590_9 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
EH2_k127_4779202_0 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 384.0
EH2_k127_4779202_1 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002533 249.0
EH2_k127_4779202_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000001319 245.0
EH2_k127_4779202_3 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000006238 160.0
EH2_k127_4779202_4 ECF-type riboflavin transporter, S component - - - 0.000000000000000000000000003031 117.0
EH2_k127_4779202_5 - - - - 0.00005141 54.0
EH2_k127_4819857_0 peptidase activity, acting on L-amino acid peptides K09607 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 390.0
EH2_k127_4819857_1 PFAM Forkhead-associated protein - - - 0.000000000000000001014 97.0
EH2_k127_4819857_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000001448 86.0
EH2_k127_4830593_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 301.0
EH2_k127_4830593_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001007 256.0
EH2_k127_4830593_2 Radical SAM domain protein K09711 - - 0.0000000000000000000000000000000000000000000000000000000001275 214.0
EH2_k127_4830593_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000000002526 86.0
EH2_k127_4830593_4 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.000001397 56.0
EH2_k127_4834486_0 domain, Protein - - - 0.00000000000000004979 97.0
EH2_k127_4834486_1 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K02557,K03286 - - 0.00000000002699 78.0
EH2_k127_4834486_2 Right handed beta helix region - - - 0.00000000006158 77.0
EH2_k127_4853823_0 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000218 202.0
EH2_k127_4853823_1 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000008828 127.0
EH2_k127_4865444_0 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003998 282.0
EH2_k127_4865444_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008257 298.0
EH2_k127_4865444_10 Putative TM nitroreductase - - - 0.00000000000000000000000000000000007985 148.0
EH2_k127_4865444_11 Belongs to the UPF0251 family - - - 0.0000000000000000000002405 99.0
EH2_k127_4865444_2 Kef-type K transport K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001963 283.0
EH2_k127_4865444_3 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000006849 262.0
EH2_k127_4865444_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002342 251.0
EH2_k127_4865444_5 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000009113 226.0
EH2_k127_4865444_6 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.00000000000000000000000000000000000000000000000000000000006991 209.0
EH2_k127_4865444_7 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000004018 194.0
EH2_k127_4865444_8 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000009239 175.0
EH2_k127_4865444_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000005772 151.0
EH2_k127_4912824_0 Type II/IV secretion system protein K07332 - - 7.957e-218 690.0
EH2_k127_4912824_1 Type II/IV secretion system protein K07332 - - 3.14e-213 674.0
EH2_k127_4912824_2 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 302.0
EH2_k127_4912824_3 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000347 241.0
EH2_k127_4912824_4 PFAM PKD domain containing protein - - - 0.00000007586 64.0
EH2_k127_49945_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 5.404e-223 704.0
EH2_k127_49945_1 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001176 221.0
EH2_k127_49945_2 Archaeal Nre, N-terminal - - - 0.0000000000000000000001615 98.0
EH2_k127_5145526_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 390.0
EH2_k127_5145526_1 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 294.0
EH2_k127_5145526_2 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000001229 143.0
EH2_k127_5145526_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000005056 85.0
EH2_k127_5145526_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002182 60.0
EH2_k127_514637_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 556.0
EH2_k127_514637_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000001568 66.0
EH2_k127_514637_2 Molybdopterin K03636 - - 0.0000003934 57.0
EH2_k127_5160263_0 aldo keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 458.0
EH2_k127_5160263_1 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 417.0
EH2_k127_5160263_2 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 379.0
EH2_k127_5160263_3 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 360.0
EH2_k127_5160263_4 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 296.0
EH2_k127_5160263_5 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000008548 185.0
EH2_k127_5160263_6 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 - 0.000000000000000000000000000002055 125.0
EH2_k127_5160263_7 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.0000000000000000000001534 105.0
EH2_k127_5160263_8 SpoVT / AbrB like domain - - - 0.0000000003301 65.0
EH2_k127_5197512_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 439.0
EH2_k127_5197512_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 411.0
EH2_k127_5197512_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 302.0
EH2_k127_5197512_3 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000005336 109.0
EH2_k127_5204965_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 611.0
EH2_k127_5204965_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 334.0
EH2_k127_5204965_2 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000004946 276.0
EH2_k127_5204965_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000000000000000000003169 241.0
EH2_k127_5204965_4 Protein of unknown function TPD sequence-motif - - - 0.0000000000000000000000000000000000000000000000000000000002214 214.0
EH2_k127_5206799_0 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 516.0
EH2_k127_5206799_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 466.0
EH2_k127_5206799_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 458.0
EH2_k127_5206799_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 372.0
EH2_k127_5206799_4 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009161 228.0
EH2_k127_5206799_5 OsmC-like protein - - - 0.0000000000000000000000000000000212 131.0
EH2_k127_5206799_6 - - - - 0.00000000000000000000000000002248 124.0
EH2_k127_5206799_7 - - - - 0.000000000157 67.0
EH2_k127_5206799_8 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0004293 44.0
EH2_k127_5258949_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 551.0
EH2_k127_5258949_1 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 340.0
EH2_k127_5258949_2 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000000000000000003238 184.0
EH2_k127_5258949_3 PFAM NIL domain - - - 0.000000000000000000000000000000000194 136.0
EH2_k127_5263457_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 412.0
EH2_k127_5263457_1 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 334.0
EH2_k127_5263457_2 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000001208 166.0
EH2_k127_5263457_3 Belongs to the peptidase S8 family - - - 0.00003459 58.0
EH2_k127_5293793_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 1.171e-225 749.0
EH2_k127_5293793_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 611.0
EH2_k127_5293793_10 PFAM amino acid-binding ACT domain protein - - - 0.00009791 50.0
EH2_k127_5293793_2 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 509.0
EH2_k127_5293793_3 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 377.0
EH2_k127_5293793_4 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 387.0
EH2_k127_5293793_5 CO dehydrogenase acetyl-CoA synthase K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000001078 271.0
EH2_k127_5293793_6 Anion-transporting ATPase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000509 237.0
EH2_k127_5293793_7 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000329 234.0
EH2_k127_5293793_8 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000001389 194.0
EH2_k127_5293793_9 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000007248 120.0
EH2_k127_5320711_0 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 360.0
EH2_k127_5320711_1 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 351.0
EH2_k127_5320711_10 ABC transporter K02004 - - 0.0000000000000002048 94.0
EH2_k127_5320711_11 Glycosyl transferase family 41 - - - 0.00000000009422 75.0
EH2_k127_5320711_12 TIGRFAM RHS repeat-associated core domain - - - 0.000000002088 72.0
EH2_k127_5320711_13 membrane - - - 0.00000001261 66.0
EH2_k127_5320711_14 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000977 67.0
EH2_k127_5320711_15 archaeal coiled-coil protein - - - 0.00001617 50.0
EH2_k127_5320711_16 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0001045 54.0
EH2_k127_5320711_17 SMART zinc finger, RanBP2-type - - - 0.0001281 53.0
EH2_k127_5320711_18 ABC transporter permease K02004,K16918 - - 0.0001783 55.0
EH2_k127_5320711_19 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0004016 49.0
EH2_k127_5320711_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007317 251.0
EH2_k127_5320711_3 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000005391 241.0
EH2_k127_5320711_4 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000002268 222.0
EH2_k127_5320711_5 Desulfoferrodoxin K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000005397 170.0
EH2_k127_5320711_6 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000002791 171.0
EH2_k127_5320711_7 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000000000000000000000003743 168.0
EH2_k127_5320711_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000006095 137.0
EH2_k127_5320711_9 UbiE COQ5 methyltransferase K07755 - 2.1.1.137 0.00000000000000000685 94.0
EH2_k127_5329723_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1046.0
EH2_k127_5329723_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 365.0
EH2_k127_5329723_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000005858 203.0
EH2_k127_5329723_3 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000007917 185.0
EH2_k127_5329723_4 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000001768 147.0
EH2_k127_5329723_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000005507 139.0
EH2_k127_5329723_6 EamA-like transporter family - - - 0.0000000000117 75.0
EH2_k127_5362088_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.358e-235 756.0
EH2_k127_5370095_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 628.0
EH2_k127_5370095_1 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 392.0
EH2_k127_5370095_2 - - - - 0.0000000000000000000004346 102.0
EH2_k127_5370095_3 Protein of unknown function (DUF531) K09725 - - 0.000000000000000005701 84.0
EH2_k127_5370095_4 Belongs to the eukaryotic ribosomal protein eL32 family K02912 - - 0.00003966 57.0
EH2_k127_5379212_0 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000001089 198.0
EH2_k127_5379212_1 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000001445 164.0
EH2_k127_5379212_2 COG1100 GTPase SAR1 and related small G - - - 0.00000000000000000000000000009721 126.0
EH2_k127_54023_0 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 425.0
EH2_k127_54023_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 350.0
EH2_k127_54023_10 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000001239 127.0
EH2_k127_54023_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005416 284.0
EH2_k127_54023_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002575 232.0
EH2_k127_54023_4 Cache domain - - - 0.0000000000000000000000000000000000000000000000001521 199.0
EH2_k127_54023_5 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000005447 180.0
EH2_k127_54023_6 Chemotaxis protein cheY K03413 - - 0.00000000000000000000000000000000002225 139.0
EH2_k127_54023_7 Chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000000000000938 138.0
EH2_k127_54023_8 CheC-like family K03410 - - 0.00000000000000000000000000000003027 133.0
EH2_k127_54023_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 0.0000000000000000000000000000003361 124.0
EH2_k127_5425689_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007081 254.0
EH2_k127_5425689_1 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000000002516 190.0
EH2_k127_5436253_0 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 300.0
EH2_k127_5436253_1 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000001781 191.0
EH2_k127_5436253_2 PFAM aminotransferase class I and II K00812 - 2.6.1.1 0.00000000004918 65.0
EH2_k127_5442540_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 572.0
EH2_k127_5442540_1 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.00000000000000000000000000000000000006728 148.0
EH2_k127_5442540_2 PFAM PKD domain containing protein - - - 0.000000000000004351 90.0
EH2_k127_5442540_3 FR47-like protein - - - 0.0001693 51.0
EH2_k127_5467463_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009823 269.0
EH2_k127_5467463_1 - - - - 0.00000000000000000000000000000000000000000000000000000000005014 227.0
EH2_k127_5467463_2 protein conserved in archaea - - - 0.00000000000000000000000001576 112.0
EH2_k127_5467463_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000001814 62.0
EH2_k127_5467463_4 COG0170 Dolichol kinase - - - 0.00004651 54.0
EH2_k127_546749_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 395.0
EH2_k127_546749_1 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 292.0
EH2_k127_546749_2 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000004158 66.0
EH2_k127_5471027_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 352.0
EH2_k127_5471027_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 335.0
EH2_k127_5471027_2 Alkyl hydroperoxide reductase F subunit K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
EH2_k127_5471027_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000003801 241.0
EH2_k127_5471027_4 SIS domain K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000001264 188.0
EH2_k127_5471027_5 MoeZ MoeB domain K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000007965 155.0
EH2_k127_5471027_6 PFAM thioesterase superfamily - - - 0.0000000000000000000000000001047 117.0
EH2_k127_5471027_7 to Saccharomyces cerevisiae RPN11 (YFR004W) K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000000000336 78.0
EH2_k127_5471027_8 Ubiquitin-conjugating enzyme E2, catalytic domain homologues K10573 - 2.3.2.23 0.000000008267 63.0
EH2_k127_5482791_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.255e-266 853.0
EH2_k127_5482791_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.829e-257 808.0
EH2_k127_5482791_10 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 366.0
EH2_k127_5482791_11 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 337.0
EH2_k127_5482791_12 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 329.0
EH2_k127_5482791_13 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 307.0
EH2_k127_5482791_14 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
EH2_k127_5482791_15 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
EH2_k127_5482791_16 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002962 262.0
EH2_k127_5482791_17 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001157 273.0
EH2_k127_5482791_18 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002585 254.0
EH2_k127_5482791_19 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000001195 220.0
EH2_k127_5482791_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 622.0
EH2_k127_5482791_20 PFAM HD domain K03698 - - 0.00000000000000000000000000000000000000000000000000001138 204.0
EH2_k127_5482791_21 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000004261 216.0
EH2_k127_5482791_22 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000000002678 181.0
EH2_k127_5482791_23 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000003621 190.0
EH2_k127_5482791_24 FMN binding K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000002104 166.0
EH2_k127_5482791_25 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000001381 164.0
EH2_k127_5482791_26 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000003375 157.0
EH2_k127_5482791_27 Clostripain family - - - 0.0000000000000000000000000000000000003684 157.0
EH2_k127_5482791_28 Uncharacterised protein family (UPF0179) K09730 - - 0.00000000000000000000000000000001515 131.0
EH2_k127_5482791_29 Tubulin like - - - 0.0000000000000000000000000000001456 145.0
EH2_k127_5482791_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 568.0
EH2_k127_5482791_30 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000001565 139.0
EH2_k127_5482791_31 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000002736 110.0
EH2_k127_5482791_32 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.00000000000000001402 99.0
EH2_k127_5482791_33 MoaE protein K21142 - 2.8.1.12 0.00000000000005938 78.0
EH2_k127_5482791_34 KEOPS complex Cgi121-like subunit K09119 - - 0.000000001824 65.0
EH2_k127_5482791_36 Di-glucose binding within endoplasmic reticulum - - - 0.00001159 58.0
EH2_k127_5482791_37 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.0004618 50.0
EH2_k127_5482791_4 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 510.0
EH2_k127_5482791_5 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 490.0
EH2_k127_5482791_6 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 485.0
EH2_k127_5482791_7 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 422.0
EH2_k127_5482791_8 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 413.0
EH2_k127_5482791_9 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 391.0
EH2_k127_548907_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 424.0
EH2_k127_5524867_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 539.0
EH2_k127_5524867_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000001222 59.0
EH2_k127_5546917_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002735 260.0
EH2_k127_5546917_1 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000004381 236.0
EH2_k127_5546917_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000001518 202.0
EH2_k127_5546917_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000006229 175.0
EH2_k127_5546917_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000104 162.0
EH2_k127_5546917_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000002249 138.0
EH2_k127_5563374_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 305.0
EH2_k127_5563374_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 333.0
EH2_k127_5563374_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000001777 188.0
EH2_k127_5563374_3 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000001181 111.0
EH2_k127_5563374_4 - - - - 0.00000000000000000000001005 107.0
EH2_k127_5563374_5 Uncharacterised protein family UPF0066 - - - 0.0000000000000006831 91.0
EH2_k127_5563374_7 Protein of unknown function (DUF998) - - - 0.000002795 59.0
EH2_k127_5583836_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002163 274.0
EH2_k127_5583836_1 hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000003949 188.0
EH2_k127_5673004_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 508.0
EH2_k127_5673004_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 385.0
EH2_k127_5673004_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 342.0
EH2_k127_5673004_3 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 289.0
EH2_k127_5673004_4 Oxidoreductase domain protein K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000395 287.0
EH2_k127_5673004_5 Belongs to the UPF0434 family - - - 0.0000000000000007068 82.0
EH2_k127_5673004_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000004287 66.0
EH2_k127_5673004_7 Acetyltransferase (GNAT) family - - - 0.0007889 49.0
EH2_k127_5728807_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 580.0
EH2_k127_5728807_1 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 299.0
EH2_k127_5728807_2 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000002995 180.0
EH2_k127_5728807_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000003717 146.0
EH2_k127_5728807_4 - - - - 0.0000000009616 64.0
EH2_k127_5728807_5 Tetratricopeptide repeat - - - 0.0008114 50.0
EH2_k127_5859036_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 519.0
EH2_k127_5859036_1 COG0328 Ribonuclease HI K03469 - 3.1.26.4 0.00000000000000000000000000837 114.0
EH2_k127_5906951_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006763 283.0
EH2_k127_5906951_1 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000003376 239.0
EH2_k127_5906951_2 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619 - 1.20.4.1,2.3.1.1 0.00000000001422 70.0
EH2_k127_5918731_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 355.0
EH2_k127_5918731_1 isomerase activity K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000003507 260.0
EH2_k127_5918731_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000002995 169.0
EH2_k127_5918731_3 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000001238 145.0
EH2_k127_5918731_4 Rubrerythrin - - - 0.0000001584 60.0
EH2_k127_5966792_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 571.0
EH2_k127_5966792_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 529.0
EH2_k127_5966792_10 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000001932 179.0
EH2_k127_5966792_11 helix_turn_helix ASNC type K06154 - - 0.00000000000000000000000002374 113.0
EH2_k127_5966792_12 PFAM Nitroreductase - - - 0.0000000000000003822 81.0
EH2_k127_5966792_13 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000001994 72.0
EH2_k127_5966792_14 Protein of unknown function (DUF835) - - - 0.000000000008472 80.0
EH2_k127_5966792_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 502.0
EH2_k127_5966792_3 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 483.0
EH2_k127_5966792_4 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 425.0
EH2_k127_5966792_5 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 405.0
EH2_k127_5966792_6 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 353.0
EH2_k127_5966792_7 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 301.0
EH2_k127_5966792_8 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001027 269.0
EH2_k127_5966792_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000003793 190.0
EH2_k127_6105453_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 2.943e-246 836.0
EH2_k127_6105453_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 595.0
EH2_k127_6105453_10 TraB family - - - 0.00000000000000000000000000001026 128.0
EH2_k127_6105453_11 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000009092 125.0
EH2_k127_6105453_12 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000001275 102.0
EH2_k127_6105453_13 - - - - 0.00000001886 65.0
EH2_k127_6105453_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 464.0
EH2_k127_6105453_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 433.0
EH2_k127_6105453_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000456 246.0
EH2_k127_6105453_5 RNA-binding protein of the translin family K07477 - - 0.000000000000000000000000000000000000000002495 168.0
EH2_k127_6105453_6 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000001316 158.0
EH2_k127_6105453_7 archaeal Zn-finger protein - - - 0.0000000000000000000000000000000000000005427 155.0
EH2_k127_6105453_8 Methyltransferase domain K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000007173 149.0
EH2_k127_6105453_9 Thioredoxin K03671 - - 0.000000000000000000000000000007295 124.0
EH2_k127_6107538_0 Tetratricopeptide repeat - - - 0.0000000000000000000005574 113.0
EH2_k127_6107538_1 - - - - 0.00000000005419 74.0
EH2_k127_6107538_2 Tetratricopeptide repeat - - - 0.00001149 59.0
EH2_k127_6171975_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 584.0
EH2_k127_6171975_1 GAF domain - - - 0.00000000000000000000000000000000000000001149 174.0
EH2_k127_6171975_3 - - - - 0.00000000000000000000006677 114.0
EH2_k127_6171975_4 - - - - 0.0000000000000000000001194 103.0
EH2_k127_6171975_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000003435 101.0
EH2_k127_6171975_6 PFAM glutaredoxin - - - 0.0000000000000000114 85.0
EH2_k127_6171975_7 PFAM 4Fe-4S - - - 0.0000000001828 65.0
EH2_k127_6179217_0 CobW/HypB/UreG, nucleotide-binding domain - - - 1.293e-196 621.0
EH2_k127_6179217_1 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000001171 196.0
EH2_k127_6179217_2 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000002112 175.0
EH2_k127_6179217_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000006387 159.0
EH2_k127_6179217_4 - - - - 0.0000000000000000000003629 100.0
EH2_k127_6179217_5 transcriptional regulators - - - 0.00000000000000007083 87.0
EH2_k127_6179733_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 499.0
EH2_k127_6179733_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 293.0
EH2_k127_6179733_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001614 283.0
EH2_k127_6179733_3 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000001018 188.0
EH2_k127_6179733_4 - - - - 0.000000000000000000000000000000000000000000008002 177.0
EH2_k127_6179733_5 - - - - 0.00000000000000000000000000000000002668 142.0
EH2_k127_6179733_6 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000006373 49.0
EH2_k127_6188156_0 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000001037 206.0
EH2_k127_6188156_1 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000003528 134.0
EH2_k127_6225852_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 317.0
EH2_k127_6225852_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000002844 239.0
EH2_k127_6225852_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000006559 123.0
EH2_k127_6228146_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000002028 240.0
EH2_k127_6228146_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
EH2_k127_6228146_2 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001195 205.0
EH2_k127_6228146_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000007216 175.0
EH2_k127_6228146_4 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000002941 165.0
EH2_k127_6228146_5 VIT family - - - 0.0000000000000000000000000000000004963 138.0
EH2_k127_6228146_6 Transcriptional regulator K07722 - - 0.0000000000000000000000000001795 126.0
EH2_k127_6228146_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000006908 72.0
EH2_k127_6228146_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000001042 58.0
EH2_k127_6228146_9 TIGRFAM cobalt ABC transporter, permease protein CbiQ K02008 - - 0.00000001114 65.0
EH2_k127_6240841_0 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000000000000000000000000000000000000000002254 220.0
EH2_k127_6240841_1 COG1361 S-layer domain - - - 0.0000000006938 64.0
EH2_k127_6240841_2 Probable transposase K07496 - - 0.0001999 50.0
EH2_k127_6273918_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 391.0
EH2_k127_6273918_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
EH2_k127_6273918_2 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000006877 194.0
EH2_k127_6273918_3 AAA domain - - - 0.0000000000000000000000000000000000000000000001422 176.0
EH2_k127_6273918_4 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.000000000000000001487 99.0
EH2_k127_6273918_5 4Fe-4S dicluster domain - - - 0.00000000000000001726 86.0
EH2_k127_6273918_6 - K21029 - 2.7.7.80 0.00001588 55.0
EH2_k127_6284542_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 554.0
EH2_k127_6284542_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
EH2_k127_6284542_2 - - - - 0.0001765 46.0
EH2_k127_6294369_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
EH2_k127_6294369_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 483.0
EH2_k127_6294369_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
EH2_k127_6294369_3 myo-inosose-2 dehydratase activity K10709 - - 0.000000000000000000000000000000000006684 149.0
EH2_k127_6294369_4 - - - - 0.000000000000000633 81.0
EH2_k127_6294369_5 transcriptional regulators - - - 0.00000000003459 68.0
EH2_k127_6301061_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 558.0
EH2_k127_6301061_1 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000005787 169.0
EH2_k127_6301061_2 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000006186 96.0
EH2_k127_6301061_3 binds to the 23S rRNA K02922 - - 0.000000000000000007193 83.0
EH2_k127_6339194_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 378.0
EH2_k127_6339194_1 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 374.0
EH2_k127_6339194_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000001726 222.0
EH2_k127_6339194_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000002214 202.0
EH2_k127_6343219_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 7.321e-195 618.0
EH2_k127_6343219_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 320.0
EH2_k127_6343219_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004292 300.0
EH2_k127_6343219_3 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000208 246.0
EH2_k127_6343219_4 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000002854 199.0
EH2_k127_6343219_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000005574 146.0
EH2_k127_6343219_6 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000001299 142.0
EH2_k127_6343219_7 - - - - 0.000000003809 62.0
EH2_k127_6343219_8 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000552 63.0
EH2_k127_6343307_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005567 282.0
EH2_k127_6343307_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006082 282.0
EH2_k127_6343307_2 Family 5 K02035,K13889 - - 0.000000000000000000000000000000000000000000000000000000000000006002 237.0
EH2_k127_6343307_3 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15586 - - 0.0000000000000000000000000000000000000000000000000203 191.0
EH2_k127_6343307_4 GrpB protein - - - 0.000000000000000000000000000000004621 135.0
EH2_k127_6346780_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000002217 162.0
EH2_k127_6346780_3 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.000000000000001561 82.0
EH2_k127_6346780_4 EamA-like transporter family - - - 0.00001727 54.0
EH2_k127_6346927_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 491.0
EH2_k127_6346927_1 Signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000001461 172.0
EH2_k127_6346927_2 membrane-associated protein domain - - - 0.0008573 46.0
EH2_k127_6454587_0 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 333.0
EH2_k127_6454587_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 323.0
EH2_k127_6454587_10 PIN domain of ribonuclease K07060 - - 0.00000000000000000003846 96.0
EH2_k127_6454587_11 Acetyltransferase (GNAT) domain - - - 0.000000000000004975 76.0
EH2_k127_6454587_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000006874 83.0
EH2_k127_6454587_2 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 297.0
EH2_k127_6454587_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000292 217.0
EH2_k127_6454587_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000000000000000006925 189.0
EH2_k127_6454587_5 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.0000000000000000000000000000000000000000000000007829 181.0
EH2_k127_6454587_6 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000007135 173.0
EH2_k127_6454587_7 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000004241 131.0
EH2_k127_6454587_8 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.000000000000000000000000005579 116.0
EH2_k127_6454587_9 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000163 116.0
EH2_k127_6483167_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 512.0
EH2_k127_6483167_1 - - - - 0.000000000000000004067 93.0
EH2_k127_6483167_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000001159 91.0
EH2_k127_6499074_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 428.0
EH2_k127_6499074_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 349.0
EH2_k127_6499074_10 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001102 202.0
EH2_k127_6499074_11 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000003522 204.0
EH2_k127_6499074_12 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000002965 128.0
EH2_k127_6499074_13 Ion channel - - - 0.000000000000003857 81.0
EH2_k127_6499074_14 - - - - 0.0000001943 61.0
EH2_k127_6499074_2 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 345.0
EH2_k127_6499074_3 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 355.0
EH2_k127_6499074_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 308.0
EH2_k127_6499074_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001165 276.0
EH2_k127_6499074_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003973 274.0
EH2_k127_6499074_7 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001175 266.0
EH2_k127_6499074_8 conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003535 256.0
EH2_k127_6499074_9 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009984 249.0
EH2_k127_6506299_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 494.0
EH2_k127_6506299_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005543 265.0
EH2_k127_6506299_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.00000000000000000000000000000000000000000000000000000001169 204.0
EH2_k127_6537928_0 PFAM DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 478.0
EH2_k127_6537928_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 447.0
EH2_k127_6537928_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 332.0
EH2_k127_6537928_3 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 306.0
EH2_k127_6537928_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008137 280.0
EH2_k127_6537928_5 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002656 179.0
EH2_k127_6537928_6 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000009103 141.0
EH2_k127_6537928_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000005865 139.0
EH2_k127_6544909_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 550.0
EH2_k127_6544909_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 532.0
EH2_k127_6544909_10 PFAM CBS domain containing protein - - - 0.00000000000000000000000002298 114.0
EH2_k127_6544909_11 EamA-like transporter family - - - 0.0000035 58.0
EH2_k127_6544909_12 - - - - 0.00002086 53.0
EH2_k127_6544909_13 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0008835 45.0
EH2_k127_6544909_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 426.0
EH2_k127_6544909_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 361.0
EH2_k127_6544909_4 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 312.0
EH2_k127_6544909_5 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004652 289.0
EH2_k127_6544909_6 Isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000292 269.0
EH2_k127_6544909_7 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003813 267.0
EH2_k127_6544909_8 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000001101 152.0
EH2_k127_6544909_9 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000000003095 149.0
EH2_k127_6606151_0 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000006179 169.0
EH2_k127_6606151_1 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000007011 143.0
EH2_k127_6606151_2 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000000008991 139.0
EH2_k127_6606151_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000001034 103.0
EH2_k127_6606151_4 6-phosphogluconolactonase activity - - - 0.0000000000000001455 96.0
EH2_k127_6606151_5 OmpA family - - - 0.0000000109 70.0
EH2_k127_6614866_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000002124 259.0
EH2_k127_6614866_1 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000001675 242.0
EH2_k127_6614866_2 B12 binding domain K14084 - - 0.0000000000000000000000000000000000000000000000000001286 193.0
EH2_k127_6614866_3 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000002659 114.0
EH2_k127_6614866_4 - - - - 0.0000000000000000000006648 103.0
EH2_k127_6702513_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 520.0
EH2_k127_6702513_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 361.0
EH2_k127_6702513_10 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000001428 86.0
EH2_k127_6702513_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 312.0
EH2_k127_6702513_3 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 312.0
EH2_k127_6702513_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000009881 206.0
EH2_k127_6702513_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000001248 184.0
EH2_k127_6702513_6 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000000000000000000000006787 159.0
EH2_k127_6702513_7 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000001745 153.0
EH2_k127_6702513_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000000001044 135.0
EH2_k127_6702513_9 YHS domain - - - 0.000000000000000039 81.0
EH2_k127_671824_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 580.0
EH2_k127_671824_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 504.0
EH2_k127_671824_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000001844 88.0
EH2_k127_671824_11 CRS1_YhbY K07574 - - 0.0000001994 57.0
EH2_k127_671824_12 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000005359 62.0
EH2_k127_671824_2 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 268.0
EH2_k127_671824_3 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009617 266.0
EH2_k127_671824_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000002147 251.0
EH2_k127_671824_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000001898 232.0
EH2_k127_671824_6 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000003283 199.0
EH2_k127_671824_7 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000004045 216.0
EH2_k127_671824_8 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000121 175.0
EH2_k127_671824_9 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000004619 145.0
EH2_k127_6944776_0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000007533 156.0
EH2_k127_6944776_1 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.000000000000000000000000000000002682 143.0
EH2_k127_6944776_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000000009509 109.0
EH2_k127_6953660_0 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.000000000000000000000000000000000000001214 156.0
EH2_k127_6953660_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000002596 123.0
EH2_k127_6967707_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 520.0
EH2_k127_6967707_1 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000000000000000000001175 139.0
EH2_k127_6967707_2 protein conserved in archaea - - - 0.0000000000000000000306 96.0
EH2_k127_6981215_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 449.0
EH2_k127_6981215_1 Histidine kinase-like ATPases - - - 0.0000000000006083 80.0
EH2_k127_6981215_3 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0007277 50.0
EH2_k127_7005646_0 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000002149 149.0
EH2_k127_716218_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000185 284.0
EH2_k127_716218_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001502 253.0
EH2_k127_716218_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000514 255.0
EH2_k127_716218_3 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000008007 181.0
EH2_k127_716218_4 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000001899 113.0
EH2_k127_716218_5 - - - - 0.00000000000000002673 85.0
EH2_k127_7177395_0 Response regulator receiver domain - - - 0.00000000000000000000000004073 114.0
EH2_k127_7177395_1 DNA-binding transcription factor activity K18297 - - 0.000000000000000001269 96.0
EH2_k127_7177395_2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000002178 64.0
EH2_k127_7257587_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1513.0
EH2_k127_7257587_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.731e-271 861.0
EH2_k127_7257587_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.171e-268 839.0
EH2_k127_7257587_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 503.0
EH2_k127_7257587_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
EH2_k127_7257587_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000004114 215.0
EH2_k127_7257587_6 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000002965 183.0
EH2_k127_7257587_7 - - - - 0.000000000003812 74.0
EH2_k127_7257587_8 DnaB-like helicase C terminal domain - - - 0.0000002959 56.0
EH2_k127_7257587_9 Double zinc ribbon - - - 0.00009721 55.0
EH2_k127_7264675_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 313.0
EH2_k127_7264675_1 Protein of unknown function DUF58 - - - 0.000000000000004135 89.0
EH2_k127_7264675_2 Domain of unknown function K20276 - - 0.000008633 60.0
EH2_k127_7267463_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 523.0
EH2_k127_7267463_1 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 291.0
EH2_k127_7274965_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1078.0
EH2_k127_7274965_1 ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 379.0
EH2_k127_7274965_10 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000004199 171.0
EH2_k127_7274965_11 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000001632 83.0
EH2_k127_7274965_12 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000427 85.0
EH2_k127_7274965_13 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000007799 76.0
EH2_k127_7274965_14 - - - - 0.00000000009672 64.0
EH2_k127_7274965_15 Belongs to the UPF0218 family K09735 - - 0.0000000002758 63.0
EH2_k127_7274965_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 378.0
EH2_k127_7274965_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 366.0
EH2_k127_7274965_4 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 336.0
EH2_k127_7274965_5 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 338.0
EH2_k127_7274965_6 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000008375 283.0
EH2_k127_7274965_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001656 236.0
EH2_k127_7274965_8 PFAM Major Facilitator Superfamily K19576 - - 0.0000000000000000000000000000000000000000000000000000000000234 220.0
EH2_k127_7274965_9 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000000000000000001621 207.0
EH2_k127_7318392_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.965e-254 796.0
EH2_k127_7318392_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.69e-243 756.0
EH2_k127_7318392_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000137 192.0
EH2_k127_7318392_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000002177 108.0
EH2_k127_7318392_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000003861 64.0
EH2_k127_7335223_0 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000000000000000000000000000000000002551 206.0
EH2_k127_7335223_1 - K06921 - - 0.000000000000000000000000000000000000000000000000000008192 203.0
EH2_k127_7335223_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000001172 135.0
EH2_k127_7335223_3 Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000008947 89.0
EH2_k127_7335223_4 Transcriptional regulators - - - 0.0000000000000305 83.0
EH2_k127_7335223_5 cellulase activity - - - 0.00012 54.0
EH2_k127_7335223_6 - - - - 0.0001627 48.0
EH2_k127_7335223_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0003039 45.0
EH2_k127_73419_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 480.0
EH2_k127_73419_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 475.0
EH2_k127_73419_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001855 256.0
EH2_k127_73419_3 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000002241 202.0
EH2_k127_73419_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000002112 150.0
EH2_k127_73419_5 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000003298 100.0
EH2_k127_73419_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000002643 75.0
EH2_k127_73419_7 Sugar (and other) transporter - - - 0.00001685 57.0
EH2_k127_7356817_0 PPE family - - - 0.00009655 52.0
EH2_k127_7356817_1 deoxyhypusine monooxygenase activity - - - 0.00009766 53.0
EH2_k127_7422053_0 GXGXG motif - - - 2.437e-298 952.0
EH2_k127_7422053_1 Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 440.0
EH2_k127_7473854_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 318.0
EH2_k127_7473854_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000001074 212.0
EH2_k127_7473854_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000002074 192.0
EH2_k127_7473854_3 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000003047 158.0
EH2_k127_7473854_4 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000005109 99.0
EH2_k127_7526573_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 610.0
EH2_k127_7526573_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 415.0
EH2_k127_7526573_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000002245 172.0
EH2_k127_7526573_3 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000000000000000000000000000000000000000000007921 191.0
EH2_k127_7526573_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000002276 142.0
EH2_k127_7526573_5 PAS domain - - - 0.00000000000000004951 84.0
EH2_k127_7564197_0 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008018 259.0
EH2_k127_7564197_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000007592 211.0
EH2_k127_7564197_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000000000000000000111 182.0
EH2_k127_7564197_3 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000001124 174.0
EH2_k127_7564197_4 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001294 91.0
EH2_k127_7599969_0 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000000000006018 182.0
EH2_k127_7599969_1 Clostripain family - - - 0.00000000000000000000000000000000000000000001219 177.0
EH2_k127_76079_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.858e-274 863.0
EH2_k127_76079_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 354.0
EH2_k127_76079_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000002354 131.0
EH2_k127_7654550_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 266.0
EH2_k127_7654550_1 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000004291 233.0
EH2_k127_7654550_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000004054 126.0
EH2_k127_7654550_3 PKD domain - - - 0.0000000000000000003369 103.0
EH2_k127_7654550_4 Pkd domain containing protein - - - 0.0000000001092 75.0
EH2_k127_7654550_5 Right handed beta helix region - - - 0.000000003531 67.0
EH2_k127_7681828_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 490.0
EH2_k127_7681828_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 466.0
EH2_k127_7681828_2 Major facilitator Superfamily K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 348.0
EH2_k127_7681828_3 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000246 101.0
EH2_k127_7681828_4 transcriptional regulator, SARP family - - - 0.000000000002389 80.0
EH2_k127_772592_0 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002698 280.0
EH2_k127_772592_1 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000009315 164.0
EH2_k127_772592_2 Aminotransferase class-III K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006560,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0010121,GO:0016054,GO:0016740,GO:0016769,GO:0019493,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.000000000000002767 77.0
EH2_k127_772592_3 Protein of unknown function (DUF998) - - - 0.0007869 50.0
EH2_k127_7750029_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000001251 189.0
EH2_k127_7750029_1 amino acid - - - 0.0000000000000000000000000000000443 139.0
EH2_k127_7776111_0 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 376.0
EH2_k127_7776111_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 346.0
EH2_k127_7776111_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000002575 157.0
EH2_k127_779331_0 helicase superfamily c-terminal domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 580.0
EH2_k127_779331_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 445.0
EH2_k127_779331_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 402.0
EH2_k127_779331_3 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000001329 188.0
EH2_k127_779331_4 Iron-sulphur cluster biosynthesis K15724 - - 0.000000000000000001048 89.0
EH2_k127_779331_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000002068 82.0
EH2_k127_779331_6 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.00000000353 58.0
EH2_k127_779331_7 - - - - 0.000000003827 59.0
EH2_k127_7806967_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 490.0
EH2_k127_7806967_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 434.0
EH2_k127_7806967_2 PFAM NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000001039 130.0
EH2_k127_7806967_3 - - - - 0.000000000000000003173 92.0
EH2_k127_784278_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 352.0
EH2_k127_784278_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000009375 225.0
EH2_k127_7892695_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 585.0
EH2_k127_7892695_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 522.0
EH2_k127_7892695_10 Protein of unknown function DUF131 - - - 0.000000003583 63.0
EH2_k127_7892695_11 Gar1/Naf1 RNA binding region K07569 - - 0.00002937 50.0
EH2_k127_7892695_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 448.0
EH2_k127_7892695_3 protein conserved in archaea K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000002409 238.0
EH2_k127_7892695_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000009226 233.0
EH2_k127_7892695_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000023 186.0
EH2_k127_7892695_6 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000005386 193.0
EH2_k127_7892695_7 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001964 130.0
EH2_k127_7892695_8 - - - - 0.00000000000003872 76.0
EH2_k127_7892695_9 Transposase, IS605 OrfB family K07496 - - 0.000000000001132 72.0
EH2_k127_7898223_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 3.488e-216 684.0
EH2_k127_7898223_1 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 398.0
EH2_k127_7898223_10 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000007183 198.0
EH2_k127_7898223_11 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000002031 194.0
EH2_k127_7898223_12 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000399 172.0
EH2_k127_7898223_13 Saccharopine dehydrogenase K00290,K19064 - 1.4.1.18,1.5.1.7 0.0000000000000000000000000000000000000000002999 173.0
EH2_k127_7898223_14 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000001072 166.0
EH2_k127_7898223_15 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000000000000000000000000000000004693 153.0
EH2_k127_7898223_16 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000003731 151.0
EH2_k127_7898223_17 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000007607 135.0
EH2_k127_7898223_18 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000007022 140.0
EH2_k127_7898223_19 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000001731 128.0
EH2_k127_7898223_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 396.0
EH2_k127_7898223_20 Major Facilitator Superfamily - - - 0.000000000000000000000000000007379 134.0
EH2_k127_7898223_21 excinuclease ABC, C subunit - - - 0.000000000000000000000000371 111.0
EH2_k127_7898223_22 rubredoxin - - - 0.000000000000000000002658 94.0
EH2_k127_7898223_23 Protein of unknown function (DUF1614) - - - 0.000000000000000000008134 102.0
EH2_k127_7898223_24 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000001704 95.0
EH2_k127_7898223_25 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000006028 89.0
EH2_k127_7898223_26 PFAM CBS domain - - - 0.0000000000000000634 87.0
EH2_k127_7898223_27 Small-conductance mechanosensitive channel - - - 0.000000000000000296 87.0
EH2_k127_7898223_28 - - - - 0.000000000000004112 77.0
EH2_k127_7898223_29 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000001688 79.0
EH2_k127_7898223_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 390.0
EH2_k127_7898223_30 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.00000000001368 75.0
EH2_k127_7898223_31 succinate dehydrogenase activity K00242,K00246 - - 0.0000000001028 68.0
EH2_k127_7898223_32 PFAM CBS domain - - - 0.0000000001333 68.0
EH2_k127_7898223_33 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000156 60.0
EH2_k127_7898223_34 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000003255 59.0
EH2_k127_7898223_4 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 385.0
EH2_k127_7898223_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 364.0
EH2_k127_7898223_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 323.0
EH2_k127_7898223_7 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 293.0
EH2_k127_7898223_8 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 294.0
EH2_k127_7898223_9 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005293 248.0
EH2_k127_7905268_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.345e-209 669.0
EH2_k127_7905268_1 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 553.0
EH2_k127_7905268_10 PAS domain K02488 - 2.7.7.65 0.0000000000006802 81.0
EH2_k127_7905268_11 - - - - 0.0000000001791 74.0
EH2_k127_7905268_12 lipopolysaccharide core region biosynthetic process - - - 0.000000001048 68.0
EH2_k127_7905268_13 Protein of unknown function (DUF835) - - - 0.000000003976 65.0
EH2_k127_7905268_14 P-type ATPase K17686 GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.54 0.000001674 49.0
EH2_k127_7905268_15 regulation of centriole-centriole cohesion K16464 GO:0000086,GO:0000226,GO:0000278,GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0007346,GO:0008022,GO:0008104,GO:0008150,GO:0009987,GO:0010389,GO:0010457,GO:0010564,GO:0015630,GO:0016043,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022402,GO:0022406,GO:0022607,GO:0030030,GO:0030031,GO:0030997,GO:0031023,GO:0031616,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0033365,GO:0034613,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0046605,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0051179,GO:0051493,GO:0051640,GO:0051641,GO:0051726,GO:0060271,GO:0060341,GO:0065007,GO:0070507,GO:0070727,GO:0070925,GO:0071840,GO:0097711,GO:0120031,GO:0120036,GO:0140056,GO:1901987,GO:1901990,GO:1902749,GO:1903047,GO:1903827,GO:1903829,GO:1904779,GO:1904781,GO:1905515 - 0.00006264 56.0
EH2_k127_7905268_16 DNA polymerase - - - 0.0001116 51.0
EH2_k127_7905268_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004609 292.0
EH2_k127_7905268_3 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006636 288.0
EH2_k127_7905268_4 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000002351 233.0
EH2_k127_7905268_5 PAS domain - - - 0.00000000000000000000000000000000000003308 164.0
EH2_k127_7905268_6 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000004405 160.0
EH2_k127_7905268_7 Bacterial Ig-like domain (group 1) - - - 0.00000000000000000000000000000001904 149.0
EH2_k127_7905268_8 Beta-lactamase enzyme family K01467,K17836 - 3.5.2.6 0.00000000000000000001647 104.0
EH2_k127_7905268_9 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000005011 81.0
EH2_k127_7958321_0 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 522.0
EH2_k127_7958321_1 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001819 248.0
EH2_k127_7958321_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002344 255.0
EH2_k127_7958321_3 Uncharacterised protein family (UPF0147) K09721 - - 0.00000000000000000000000002271 111.0
EH2_k127_7958321_4 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000177 104.0
EH2_k127_7958321_5 PFAM TPR repeat-containing protein - - - 0.00000000000000000000003965 117.0
EH2_k127_7958321_6 - - - - 0.000000000000000008598 94.0
EH2_k127_7958321_7 - - - - 0.000000000000006001 75.0
EH2_k127_8043029_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 437.0
EH2_k127_8043029_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000003247 244.0
EH2_k127_8043029_2 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000005123 180.0
EH2_k127_8043029_3 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000002722 146.0
EH2_k127_8043029_4 - - - - 0.00000000000000000002159 97.0
EH2_k127_8043029_5 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000002537 100.0
EH2_k127_8115918_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 461.0
EH2_k127_8115918_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 341.0
EH2_k127_8115918_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 323.0
EH2_k127_8115918_3 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.0000000000000000000000000000000000000000000002385 182.0
EH2_k127_8115918_4 - - - - 0.00001576 56.0
EH2_k127_868559_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 420.0
EH2_k127_868559_1 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 297.0
EH2_k127_868559_2 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002364 265.0
EH2_k127_868559_3 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001238 251.0
EH2_k127_868559_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001583 198.0
EH2_k127_868559_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000008629 149.0
EH2_k127_868559_6 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000000002309 122.0
EH2_k127_868559_7 Ribosomal L29 protein K02904 - - 0.0000000000003975 76.0
EH2_k127_868559_8 COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins K03113 - - 0.0000003388 51.0
EH2_k127_929460_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 295.0
EH2_k127_929460_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000003868 230.0
EH2_k127_929460_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000004077 118.0
EH2_k127_929460_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000001673 116.0