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Overview

ID MAG01048
Name EH2_bin.3
Sample SMP0029
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class DTKX01
Order DTKX01
Family GCA-020343715
Genus
Species
Assembly information
Completeness (%) 85.75
Contamination (%) 0.76
GC content (%) 69.0
N50 (bp) 4,047
Genome size (bp) 2,262,730

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1656

Gene name Description KEGG GOs EC E-value Score Sequence
EH2_k127_1002416_0 S-layer protein - - - 0.0000000000000005043 92.0
EH2_k127_1021429_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007839 249.0
EH2_k127_1021429_1 FtsX-like permease family K02004 - - 0.0003862 52.0
EH2_k127_105569_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 510.0
EH2_k127_105569_1 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000003484 166.0
EH2_k127_105569_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000000000000000000000000000000002658 152.0
EH2_k127_1059195_0 Large-conductance mechanosensitive channel, MscL K03282 - - 0.000000006422 61.0
EH2_k127_1059195_1 Belongs to the peptidase S8 family - - - 0.0006481 53.0
EH2_k127_1090987_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 441.0
EH2_k127_1090987_1 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006793 274.0
EH2_k127_1090987_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000191 173.0
EH2_k127_1090987_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000033 153.0
EH2_k127_1105966_0 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000001861 232.0
EH2_k127_1105966_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000002763 167.0
EH2_k127_1132929_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000479 223.0
EH2_k127_1132929_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000463 177.0
EH2_k127_1132929_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.0000000000000000000001982 105.0
EH2_k127_1141344_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000002604 196.0
EH2_k127_1141344_1 Cytochrome C biogenesis protein transmembrane region - - - 0.000000001829 70.0
EH2_k127_1141847_0 ABC transporter K00400,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 354.0
EH2_k127_1141847_1 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000002504 181.0
EH2_k127_1141847_2 - - - - 0.00002848 47.0
EH2_k127_1156914_0 small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000735 255.0
EH2_k127_1156914_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000004164 151.0
EH2_k127_1156914_2 KaiC K08482 - - 0.00000000000000000000000000000002911 134.0
EH2_k127_1156914_3 Pfam:KaiC - - - 0.00000002811 63.0
EH2_k127_1169043_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0003899 54.0
EH2_k127_1194232_0 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 413.0
EH2_k127_1194232_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000001293 76.0
EH2_k127_1194232_2 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000001587 78.0
EH2_k127_1224541_0 Beta-propeller repeat - - - 0.0000007814 57.0
EH2_k127_1246122_0 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001676 302.0
EH2_k127_1246122_1 Fibronectin type III domain - - - 0.00000000003301 77.0
EH2_k127_1290184_0 Sulfate ABC transporter substrate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000202 229.0
EH2_k127_1290184_1 Binding-protein-dependent transport system inner membrane component K02018,K02046 - - 0.0000000000000000000000000000000003493 138.0
EH2_k127_1290184_2 Fibronectin type III domain - - - 0.00000000000001598 82.0
EH2_k127_1290184_3 SpoVT / AbrB like domain - - - 0.0001291 46.0
EH2_k127_1297868_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003355 267.0
EH2_k127_131872_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000001606 233.0
EH2_k127_131872_1 Fibronectin type III domain - - - 0.00000000000000000004133 102.0
EH2_k127_132129_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 377.0
EH2_k127_132129_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000004295 156.0
EH2_k127_1339676_0 cytochrome c biogenesis protein - - - 0.00000001414 67.0
EH2_k127_1344119_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 447.0
EH2_k127_1344119_1 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000001929 196.0
EH2_k127_1344119_2 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000000003811 152.0
EH2_k127_1354699_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 346.0
EH2_k127_1354699_1 4Fe-4S dicluster domain - - - 0.0000000002079 64.0
EH2_k127_1354699_2 PFAM Tetratricopeptide - - - 0.00002578 56.0
EH2_k127_1382195_0 peptidase M36 K01417 - - 0.000000000004317 80.0
EH2_k127_14065_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000005663 156.0
EH2_k127_14065_1 PFAM CAAX amino terminal protease family K07052 - - 0.00000000000003511 83.0
EH2_k127_14065_2 - - - - 0.0000001041 60.0
EH2_k127_14065_3 Bacterial lipoate protein ligase C-terminus K03800 - 6.3.1.20 0.0006797 48.0
EH2_k127_1412011_0 COG0464 ATPases of the AAA class K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 473.0
EH2_k127_1427158_0 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 474.0
EH2_k127_1427158_1 TPR Domain containing protein - - - 0.000000000000000000000000000000000000000000002896 181.0
EH2_k127_1427158_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000004207 133.0
EH2_k127_1427158_4 HAD-hyrolase-like K07025 - - 0.0005061 44.0
EH2_k127_1461665_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000002403 218.0
EH2_k127_1461665_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000007322 73.0
EH2_k127_1461665_2 DNA binding K06930 - - 0.00000000000009483 81.0
EH2_k127_1461665_3 KEOPS complex Cgi121-like subunit K09119 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000002152 61.0
EH2_k127_1468423_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.00000000000000000000000000000000000000000000326 172.0
EH2_k127_1468423_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000006579 164.0
EH2_k127_1468423_2 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity K13652,K13653 - - 0.0000000000002655 77.0
EH2_k127_1468423_3 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K01317 - 3.4.21.10 0.00004072 57.0
EH2_k127_1470308_0 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.000000000000000000000000000000109 135.0
EH2_k127_1470308_1 FAD linked K00004,K00102 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4 0.000000003212 66.0
EH2_k127_1477380_0 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000003387 190.0
EH2_k127_1477380_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000001729 103.0
EH2_k127_1477380_2 Domain of unknown function (DUF1610) K07580 - - 0.0000000000001147 75.0
EH2_k127_1477380_3 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000001998 61.0
EH2_k127_147812_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000002762 63.0
EH2_k127_1481438_0 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000007904 142.0
EH2_k127_1481438_1 Major facilitator superfamily - - - 0.0000000000000000000000001388 120.0
EH2_k127_1485265_0 SMART Parallel beta-helix repeat - - - 0.00000000000000000000000006465 126.0
EH2_k127_1494883_0 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000001186 130.0
EH2_k127_1494883_1 Protein of unknown function DUF58 - - - 0.0000000000003177 82.0
EH2_k127_1508833_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 392.0
EH2_k127_1508833_1 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000001756 110.0
EH2_k127_1508833_2 membrane - - - 0.00000000000000002919 89.0
EH2_k127_1512250_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000001869 96.0
EH2_k127_1529532_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 480.0
EH2_k127_1529532_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000006819 169.0
EH2_k127_1529532_2 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000009994 106.0
EH2_k127_1529532_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000001124 77.0
EH2_k127_1569038_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 295.0
EH2_k127_1569038_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003216 263.0
EH2_k127_1569038_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
EH2_k127_1569038_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000006038 226.0
EH2_k127_1569038_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000007904 233.0
EH2_k127_1569038_5 ATP-dependent helicase activity K10844 - 3.6.4.12 0.00000000000000002055 86.0
EH2_k127_1586385_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000001095 229.0
EH2_k127_1586385_1 Glycosyltransferase Family 4 K00743 - 2.4.1.87 0.0000000000000000000000000000000000000000000000000000005695 208.0
EH2_k127_1586385_2 MMPL family - - - 0.000000000000002851 89.0
EH2_k127_1593183_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000003175 63.0
EH2_k127_161578_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.000000000000000000000000000000000000000000000000000000000000002334 226.0
EH2_k127_161578_1 lycopene cyclase - - - 0.0000000000000000000000000000000000000000000000000005706 192.0
EH2_k127_161578_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000004192 184.0
EH2_k127_1620642_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 381.0
EH2_k127_1620642_1 Beta-Casp domain K07577 - - 0.00000000000000000008351 100.0
EH2_k127_1620642_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000003682 67.0
EH2_k127_1632080_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 324.0
EH2_k127_1632080_1 DNA binding protein K06930 - - 0.000000000000000000000000000001457 129.0
EH2_k127_1642572_0 WD40 repeats - - - 0.0000000000000000008762 98.0
EH2_k127_1648073_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 466.0
EH2_k127_1648073_1 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000001494 174.0
EH2_k127_1648073_2 PFAM CoA-binding domain protein - - - 0.0000002273 58.0
EH2_k127_1678066_0 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000002622 161.0
EH2_k127_1680588_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.31e-197 632.0
EH2_k127_1680588_1 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002861 274.0
EH2_k127_1682415_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 2.762e-213 679.0
EH2_k127_1696393_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 358.0
EH2_k127_1698224_0 NMD3 family K07562 - - 0.000000000000000000000000000000000005025 151.0
EH2_k127_1698224_1 Protein of unknown function (DUF3344) - - - 0.00000000001071 78.0
EH2_k127_1701899_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000194 141.0
EH2_k127_1703881_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 365.0
EH2_k127_1713584_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000004645 192.0
EH2_k127_1713584_1 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.0000000000000000000000000000001131 143.0
EH2_k127_1739312_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 563.0
EH2_k127_1752613_0 rhs family - - - 0.0000000000000000000000000000004992 142.0
EH2_k127_1752613_1 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 0.0005336 53.0
EH2_k127_1761586_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000001193 203.0
EH2_k127_1761586_1 metallopeptidase activity K06974 - - 0.000000000000000000000000000005164 126.0
EH2_k127_1763718_0 glycoside hydrolase, family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002951 276.0
EH2_k127_1772426_0 thiolester hydrolase activity - - - 0.000000001427 71.0
EH2_k127_1780354_0 Predicted membrane protein (DUF2085) - - - 0.00002741 48.0
EH2_k127_1780354_1 Protein of unknown function (DUF998) - - - 0.0001334 52.0
EH2_k127_1792497_0 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 437.0
EH2_k127_1792497_1 Winged helix DNA-binding domain - - - 0.00000000000001422 78.0
EH2_k127_1792497_2 domain protein - - - 0.0000006161 56.0
EH2_k127_1808161_0 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 329.0
EH2_k127_1808161_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000004735 145.0
EH2_k127_1808161_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.00004934 48.0
EH2_k127_1808161_3 - - - - 0.0006139 49.0
EH2_k127_1838656_0 metallopeptidase activity - - - 0.000425 53.0
EH2_k127_1841473_0 Calcineurin-like phosphoesterase superfamily domain K01090 - 3.1.3.16 0.0000000000000000000000000000000000004704 150.0
EH2_k127_1841473_1 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000004508 110.0
EH2_k127_1841473_2 Pfam:DUF59 - - - 0.000000000000000003286 90.0
EH2_k127_1846846_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.649e-220 694.0
EH2_k127_1846846_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 576.0
EH2_k127_1846846_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000009075 226.0
EH2_k127_1846846_3 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000008052 202.0
EH2_k127_1846846_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000002122 164.0
EH2_k127_1846846_5 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.0000000000000000000000000000000000000002101 163.0
EH2_k127_1846846_6 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000002692 162.0
EH2_k127_1846846_7 NMT1-like family K02051 - - 0.000000000000000000000000000000000000001031 161.0
EH2_k127_1846846_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000157 85.0
EH2_k127_1871991_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000001632 218.0
EH2_k127_1886562_0 Glycine cleavage system H protein K02437 - - 0.0000000000000000000000000000004882 137.0
EH2_k127_1886562_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000322 71.0
EH2_k127_1886562_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.00000007278 55.0
EH2_k127_1893375_0 PFAM Peptidase M18, aminopeptidase I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 481.0
EH2_k127_1893375_1 PQQ enzyme repeat - - - 0.00000000000000000000000000005941 132.0
EH2_k127_1894755_1 Periplasmic copper-binding protein (NosD) - - - 0.000000000000006265 91.0
EH2_k127_1894755_2 Domain of unknown function K20276 - - 0.00000001463 68.0
EH2_k127_1894755_3 PFAM PKD domain containing protein - - - 0.00006633 57.0
EH2_k127_189798_0 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003278 289.0
EH2_k127_189798_1 TonB-dependent receptor plug - - - 0.000002771 59.0
EH2_k127_1913038_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001456 312.0
EH2_k127_1913038_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000002774 216.0
EH2_k127_1914413_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 451.0
EH2_k127_1914413_1 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 421.0
EH2_k127_1914413_2 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000001303 160.0
EH2_k127_1914413_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000156 69.0
EH2_k127_1915240_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000001547 81.0
EH2_k127_1915240_1 Protein of unknown function (DUF835) - - - 0.000000008821 64.0
EH2_k127_1915240_2 Flavodoxin - - - 0.000000008957 65.0
EH2_k127_1915240_3 Belongs to the UPF0201 family K09736 - - 0.00001508 53.0
EH2_k127_1915302_0 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000002799 216.0
EH2_k127_1915302_1 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000001281 183.0
EH2_k127_1927514_0 Pectate lyase superfamily protein - - - 0.00000000000002284 77.0
EH2_k127_1927514_1 Pectate lyase - - - 0.000000000001854 79.0
EH2_k127_193205_0 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000001593 173.0
EH2_k127_193205_1 Transcriptional regulator - - - 0.0000000000000000008995 96.0
EH2_k127_1934931_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 321.0
EH2_k127_1934931_1 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000803 80.0
EH2_k127_1951016_0 Transcriptional regulator, ArsR family - - - 0.00000000194 71.0
EH2_k127_1951344_0 HemY domain protein - - - 0.000000000000000000000002933 119.0
EH2_k127_1964648_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 407.0
EH2_k127_1964648_1 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000000261 238.0
EH2_k127_1964648_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000001421 202.0
EH2_k127_1964648_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000004044 145.0
EH2_k127_1964648_4 FMN binding - - - 0.00001363 54.0
EH2_k127_1987933_0 S-layer homology domain - - - 0.0000000000000000000008309 108.0
EH2_k127_1987933_1 Rubrerythrin - - - 0.000000372 60.0
EH2_k127_1995984_0 - - - - 0.000005903 57.0
EH2_k127_1997301_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 403.0
EH2_k127_1997301_1 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.000000000000000000000000000000000000000000000000000000348 217.0
EH2_k127_1997301_2 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000116 160.0
EH2_k127_1997301_3 Kelch - - - 0.00000003385 57.0
EH2_k127_1997301_4 Glucose / Sorbosone dehydrogenase - - - 0.0000002624 57.0
EH2_k127_2000683_0 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000001849 233.0
EH2_k127_2000683_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000004713 195.0
EH2_k127_2000683_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000002652 170.0
EH2_k127_2000683_3 domain, Protein - - - 0.000000000000000000000000000000001495 148.0
EH2_k127_2000683_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000001252 110.0
EH2_k127_2000683_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.000001723 55.0
EH2_k127_2000683_6 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000009884 51.0
EH2_k127_2003760_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 460.0
EH2_k127_2003760_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 433.0
EH2_k127_2003760_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 285.0
EH2_k127_2003760_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000007493 181.0
EH2_k127_2003760_4 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000002273 158.0
EH2_k127_2003760_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000003239 111.0
EH2_k127_2003760_6 Double zinc ribbon - - - 0.000000000002904 82.0
EH2_k127_2003760_7 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.0002146 49.0
EH2_k127_2056893_0 PKD domain - - - 0.000000000000007701 88.0
EH2_k127_2056893_1 COG1520 FOG WD40-like repeat - - - 0.00002662 57.0
EH2_k127_2061958_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000005146 78.0
EH2_k127_2061958_1 CarboxypepD_reg-like domain K13276 - - 0.000000002205 69.0
EH2_k127_2062325_0 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000002408 162.0
EH2_k127_2062325_1 PFAM PKD domain containing protein - - - 0.000000000000009786 89.0
EH2_k127_2062325_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000001698 89.0
EH2_k127_2075002_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000004628 106.0
EH2_k127_2081942_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000001253 91.0
EH2_k127_210198_0 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 368.0
EH2_k127_210198_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002577 288.0
EH2_k127_210198_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000008129 221.0
EH2_k127_210198_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000008714 149.0
EH2_k127_2128274_0 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 414.0
EH2_k127_2128274_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000002707 205.0
EH2_k127_2128274_2 Right handed beta helix region - - - 0.00000005174 66.0
EH2_k127_2130177_0 S-layer homology domain - - - 0.0000106 59.0
EH2_k127_2132095_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 2.7e-322 1000.0
EH2_k127_2132095_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.922e-198 626.0
EH2_k127_2132095_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001365 243.0
EH2_k127_2132095_3 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000009459 235.0
EH2_k127_2132095_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002683 238.0
EH2_k127_2132095_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000004685 185.0
EH2_k127_2132095_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000003359 179.0
EH2_k127_2132095_7 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000004846 156.0
EH2_k127_2158279_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 338.0
EH2_k127_2165114_0 Thioredoxin-like domain - - - 0.00000000000004795 87.0
EH2_k127_2184269_0 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 396.0
EH2_k127_2184269_1 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000004145 171.0
EH2_k127_2184269_2 CarboxypepD_reg-like domain K13276 - - 0.0000000000004823 83.0
EH2_k127_2184269_3 Domain of unknown function (DUF4350) - - - 0.000001141 61.0
EH2_k127_2189190_0 Copper amine oxidase N-terminal domain - - - 0.000000000000000000000000000000000007631 139.0
EH2_k127_2189190_1 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.00000000000000000000000166 113.0
EH2_k127_2201453_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 469.0
EH2_k127_2201453_1 Iron-sulfur cluster binding protein - - - 0.000000000001301 76.0
EH2_k127_2217549_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 303.0
EH2_k127_2242793_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001564 274.0
EH2_k127_2242793_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.0000000006653 74.0
EH2_k127_2244782_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000003776 93.0
EH2_k127_2244782_1 Di-glucose binding within endoplasmic reticulum - - - 0.000000000006029 79.0
EH2_k127_2277079_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 409.0
EH2_k127_2283268_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 316.0
EH2_k127_2283268_1 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000386 202.0
EH2_k127_2283268_2 TIGRFAM bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000001815 114.0
EH2_k127_2283268_3 Integral membrane protein DUF92 - - - 0.000000000000000002062 96.0
EH2_k127_2317689_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 447.0
EH2_k127_2317689_1 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 298.0
EH2_k127_2317689_2 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 301.0
EH2_k127_2317689_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002345 247.0
EH2_k127_2317689_4 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000003625 166.0
EH2_k127_2317689_5 von Willebrand factor, type A K11912 - 2.7.11.1 0.00000000000000000000000000000001878 143.0
EH2_k127_2323307_0 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000006287 243.0
EH2_k127_2323307_1 ASCH - - - 0.000000000000000000000000000000003124 134.0
EH2_k127_2323307_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000005024 138.0
EH2_k127_2336867_0 glycoside hydrolase, family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 641.0
EH2_k127_2339175_0 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000004739 180.0
EH2_k127_2339175_1 BNR repeat-like domain K05989 - 3.2.1.40 0.00006231 56.0
EH2_k127_2372141_0 PFAM TPR repeat-containing protein - - - 0.00001662 58.0
EH2_k127_2384915_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 327.0
EH2_k127_2384915_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000006501 183.0
EH2_k127_2384915_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000001319 129.0
EH2_k127_2384915_3 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0004154 50.0
EH2_k127_2390746_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 301.0
EH2_k127_2413901_0 Fibronectin type 3 domain - - - 0.0000000000000000002216 104.0
EH2_k127_2418587_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000007111 134.0
EH2_k127_2418587_1 protein kinase activity - - - 0.000000000005376 79.0
EH2_k127_2423835_0 ATPase, AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003836 260.0
EH2_k127_2423835_1 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000006845 215.0
EH2_k127_2423835_2 PFAM methyltransferase small K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.00000000000000000000000000000000007525 144.0
EH2_k127_2423835_3 4Fe-4S binding domain protein - - - 0.0002051 52.0
EH2_k127_2424229_0 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000009749 206.0
EH2_k127_2424229_1 Toxic component of a K07060 GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904 - 0.00000000000188 75.0
EH2_k127_2424229_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000004538 70.0
EH2_k127_2443425_0 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 392.0
EH2_k127_2443425_1 NOG20192 non supervised orthologous group - - - 0.00000000008864 68.0
EH2_k127_2464826_0 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001922 304.0
EH2_k127_2466875_0 Belongs to the peptidase S8 family - - - 0.0000000001731 75.0
EH2_k127_2474981_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000001469 276.0
EH2_k127_2474981_1 PFAM TPR repeat-containing protein K00575 - 2.1.1.80 0.0000002768 64.0
EH2_k127_2482901_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 259.0
EH2_k127_2482901_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004209 234.0
EH2_k127_2482901_2 peptidase activity, acting on L-amino acid peptides K01179 - 3.2.1.4 0.0004055 49.0
EH2_k127_2523288_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.227e-300 940.0
EH2_k127_2542822_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 561.0
EH2_k127_2542822_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000001127 130.0
EH2_k127_2542822_2 PFAM PKD domain containing protein - - - 0.000000000000000000001346 108.0
EH2_k127_2554104_0 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0000000000000000000006812 106.0
EH2_k127_2599476_0 Mechanosensitive ion channel K03442 - - 0.0000001749 55.0
EH2_k127_2666959_0 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 314.0
EH2_k127_2666959_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000009125 212.0
EH2_k127_2666959_2 pfkB family carbohydrate kinase - - - 0.0000000000000000007851 94.0
EH2_k127_2683965_0 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000003579 134.0
EH2_k127_2683965_1 metallopeptidase activity - - - 0.0000000003347 74.0
EH2_k127_2696022_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 387.0
EH2_k127_2696022_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 372.0
EH2_k127_271870_0 PFAM Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000248 287.0
EH2_k127_271870_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000001745 208.0
EH2_k127_271870_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000003699 163.0
EH2_k127_271870_3 Pkd domain containing protein - - - 0.0000000000000000000001929 115.0
EH2_k127_271870_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000002494 76.0
EH2_k127_271870_5 Periplasmic copper-binding protein (NosD) - - - 0.0003704 55.0
EH2_k127_271870_6 Covalent carrier of the coenzyme of citrate lyase K01646 - - 0.0006473 47.0
EH2_k127_2736955_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 394.0
EH2_k127_2736955_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001634 274.0
EH2_k127_2736955_2 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000003416 188.0
EH2_k127_2736955_3 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000002337 159.0
EH2_k127_2736955_4 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000002085 126.0
EH2_k127_2745760_0 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000000001559 143.0
EH2_k127_2745760_1 self proteolysis K21449 - - 0.00000000000000000000001488 119.0
EH2_k127_2745760_2 zinc ion binding K04486 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 0.00000000248 68.0
EH2_k127_2745760_3 amine dehydrogenase activity - - - 0.000000005343 71.0
EH2_k127_2759483_0 Fibronectin type III domain - - - 0.0000000000002162 85.0
EH2_k127_2759483_1 Peptidase M60-like family - - - 0.000001443 62.0
EH2_k127_2793516_0 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 374.0
EH2_k127_2793516_1 cell redox homeostasis - - - 0.000000000000000003183 87.0
EH2_k127_2793516_2 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0001407 48.0
EH2_k127_2801626_0 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 337.0
EH2_k127_2805403_0 - - - - 0.0000000000000000000000000009168 124.0
EH2_k127_280760_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000001081 268.0
EH2_k127_280760_1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
EH2_k127_280760_2 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000004137 106.0
EH2_k127_280760_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000002839 82.0
EH2_k127_280760_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000002288 78.0
EH2_k127_280760_5 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000001512 68.0
EH2_k127_2809423_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000594 82.0
EH2_k127_2811575_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000996 275.0
EH2_k127_2811575_1 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000001852 161.0
EH2_k127_2811575_2 Glucose sorbosone - - - 0.000000007499 68.0
EH2_k127_2815269_0 PAS domain K02488 - 2.7.7.65 0.00000000000000000000000000000000003265 149.0
EH2_k127_2842774_0 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
EH2_k127_2842774_1 Glyco_18 K01183 - 3.2.1.14 0.00000000002823 74.0
EH2_k127_2866710_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 3.227e-211 672.0
EH2_k127_2866710_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 580.0
EH2_k127_2866710_2 exonuclease K07502 - - 0.00000000000000000004843 93.0
EH2_k127_2866710_3 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.0000000000000002 88.0
EH2_k127_2890312_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 322.0
EH2_k127_2890312_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000001451 136.0
EH2_k127_2894222_0 AMMECR1 K09141 - - 0.0000000000000000000000000000000004332 135.0
EH2_k127_2894222_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000002261 108.0
EH2_k127_2894222_2 4Fe-4S binding domain - - - 0.00000000000000000002405 91.0
EH2_k127_2894222_3 AsnC family transcriptional regulator - - - 0.0002535 46.0
EH2_k127_2907463_0 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000003362 221.0
EH2_k127_2907671_0 PFAM ABC transporter related K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 355.0
EH2_k127_2907671_1 PFAM Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000001783 176.0
EH2_k127_2907671_2 Psort location CytoplasmicMembrane, score K16927 - - 0.00000000000000000000000000000000000000007104 173.0
EH2_k127_2907671_3 Archaeal Type IV pilin, N-terminal - - - 0.000001492 58.0
EH2_k127_2924666_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 430.0
EH2_k127_2924666_1 Protein of unknown function (DUF357) K09728 - - 0.0007322 46.0
EH2_k127_2927633_0 COG1361 S-layer domain - - - 0.000000000000000000000000000000000003653 153.0
EH2_k127_2927633_1 geranylgeranyl reductase K00311 - 1.5.5.1 0.000000000000000000000001909 110.0
EH2_k127_2939026_0 PFAM FecR protein K09800,K13735 - - 0.00000000000000373 91.0
EH2_k127_2939816_0 OsmC-like protein - - - 0.00000000000000000008174 102.0
EH2_k127_2939816_1 amine dehydrogenase activity - - - 0.0000000000000000002586 104.0
EH2_k127_2939816_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000005988 58.0
EH2_k127_2939816_3 ATPase (AAA K07133 - - 0.000006756 54.0
EH2_k127_2957846_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000005029 135.0
EH2_k127_2957846_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000002284 86.0
EH2_k127_2960638_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 443.0
EH2_k127_2960638_1 CarboxypepD_reg-like domain K13276 - - 0.0000000001906 75.0
EH2_k127_2961077_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000003184 178.0
EH2_k127_2973268_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 343.0
EH2_k127_2973268_1 PKD domain - - - 0.00000000007201 76.0
EH2_k127_3003582_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 292.0
EH2_k127_3003582_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000003416 253.0
EH2_k127_3003582_2 Putative transposon-encoded protein (DUF2080) - - - 0.0000000000000002395 79.0
EH2_k127_3014026_0 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 493.0
EH2_k127_3014026_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.0000000001756 69.0
EH2_k127_3015017_0 endopeptidase inhibitor activity K03910 GO:0000003,GO:0001101,GO:0001553,GO:0001868,GO:0001869,GO:0002020,GO:0002376,GO:0002437,GO:0002438,GO:0002526,GO:0002576,GO:0002673,GO:0002682,GO:0002683,GO:0002697,GO:0002698,GO:0002920,GO:0002921,GO:0003006,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005096,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0006955,GO:0007275,GO:0007548,GO:0007565,GO:0007566,GO:0007584,GO:0007596,GO:0007597,GO:0007599,GO:0008047,GO:0008150,GO:0008152,GO:0008406,GO:0008585,GO:0009605,GO:0009611,GO:0009719,GO:0009725,GO:0009790,GO:0009892,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010037,GO:0010466,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016043,GO:0016192,GO:0019222,GO:0019538,GO:0019838,GO:0019899,GO:0019955,GO:0019956,GO:0019958,GO:0019959,GO:0019966,GO:0022411,GO:0022414,GO:0022602,GO:0022607,GO:0022617,GO:0023051,GO:0030141,GO:0030154,GO:0030162,GO:0030198,GO:0030234,GO:0030414,GO:0030449,GO:0030695,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031347,GO:0031348,GO:0031410,GO:0031667,GO:0031960,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032940,GO:0033993,GO:0034694,GO:0034695,GO:0034774,GO:0042060,GO:0042221,GO:0042493,GO:0042698,GO:0042802,GO:0042803,GO:0043062,GO:0043085,GO:0043086,GO:0043087,GO:0043120,GO:0043121,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043547,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044238,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0044877,GO:0045055,GO:0045088,GO:0045137,GO:0045824,GO:0045861,GO:0045916,GO:0046545,GO:0046660,GO:0046903,GO:0046983,GO:0048306,GO:0048403,GO:0048406,GO:0048511,GO:0048513,GO:0048519,GO:0048523,GO:0048545,GO:0048568,GO:0048583,GO:0048585,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0048863,GO:0048869,GO:0050727,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050817,GO:0050878,GO:0050896,GO:0051056,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0051345,GO:0051346,GO:0051384,GO:0051704,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060589,GO:0061134,GO:0061135,GO:0061458,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070542,GO:0070613,GO:0071704,GO:0071840,GO:0072347,GO:0072376,GO:0072378,GO:0080090,GO:0080134,GO:0097305,GO:0097708,GO:0098772,GO:0099503,GO:1901564,GO:1901654,GO:1901700,GO:1902531,GO:1903317,GO:1903318,GO:1990402,GO:2000257,GO:2000258 - 0.00000000000000000006295 104.0
EH2_k127_3015017_1 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.000000006351 66.0
EH2_k127_3015656_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001324 269.0
EH2_k127_3015656_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000002158 85.0
EH2_k127_3034241_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000119 194.0
EH2_k127_3034241_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002159 160.0
EH2_k127_3034241_2 OmpA family - - - 0.00000000276 69.0
EH2_k127_3036991_0 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000003077 248.0
EH2_k127_3036991_1 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000000001202 121.0
EH2_k127_304274_0 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000001007 134.0
EH2_k127_304274_1 4-hydroxyphenylacetate - - - 0.00000000000000000003223 91.0
EH2_k127_3072009_0 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000105 92.0
EH2_k127_3072009_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000001796 74.0
EH2_k127_3072009_2 PKD domain containing protein - - - 0.00000006751 66.0
EH2_k127_3076477_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 336.0
EH2_k127_3076477_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 257.0
EH2_k127_3076477_2 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000331 181.0
EH2_k127_3084058_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.756e-209 666.0
EH2_k127_3084058_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000463 200.0
EH2_k127_3084058_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000007665 151.0
EH2_k127_3084058_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000001968 112.0
EH2_k127_3084058_4 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000002826 99.0
EH2_k127_3084058_5 deoxyhypusine monooxygenase activity - - - 0.0000001729 57.0
EH2_k127_3086833_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000001248 192.0
EH2_k127_3086833_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000001656 154.0
EH2_k127_3094100_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000004227 112.0
EH2_k127_3102400_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
EH2_k127_3102400_1 translation initiation factor activity K03680 - - 0.000000000000000000003638 104.0
EH2_k127_3107141_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 379.0
EH2_k127_3107141_1 TP53 regulating kinase K08851 GO:0000408,GO:0001558,GO:0002039,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023051,GO:0023056,GO:0030307,GO:0031974,GO:0031981,GO:0032006,GO:0032008,GO:0032991,GO:0034641,GO:0036211,GO:0040008,GO:0040014,GO:0040018,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045927,GO:0046483,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048638,GO:0048639,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051128,GO:0051239,GO:0051240,GO:0065007,GO:0070013,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901796,GO:1902531,GO:1902533 2.7.11.1 0.0000001288 54.0
EH2_k127_3150931_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 340.0
EH2_k127_3150931_1 PFAM Hemerythrin HHE cation binding domain - - - 0.0000006825 53.0
EH2_k127_3150931_2 Transcriptional regulator - - - 0.00004398 54.0
EH2_k127_3154644_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.05e-254 799.0
EH2_k127_3154644_1 Fibronectin type III domain - - - 0.000001099 55.0
EH2_k127_3154644_2 transglutaminase domain protein - - - 0.0002468 54.0
EH2_k127_3154820_0 Pkd domain containing protein - - - 0.0000000002779 74.0
EH2_k127_31744_0 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 345.0
EH2_k127_31744_1 Clostripain family - - - 0.000000000000000000000000000000004548 144.0
EH2_k127_31744_2 PFAM regulatory protein, ArsR K21903 - - 0.0000000000000000000000001015 111.0
EH2_k127_31744_3 AAA ATPase central domain protein - - - 0.000002533 61.0
EH2_k127_31744_4 MMPL family K06994 - - 0.00004753 55.0
EH2_k127_3175884_0 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000001864 233.0
EH2_k127_3175884_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000002272 220.0
EH2_k127_3175884_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000006559 181.0
EH2_k127_3175884_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000313 155.0
EH2_k127_3175884_4 - - - - 0.00000000000000003563 88.0
EH2_k127_318031_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 352.0
EH2_k127_318031_1 CoA binding domain - - - 0.0000000000000000000000001201 120.0
EH2_k127_318031_2 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.000000000000000003607 99.0
EH2_k127_3203479_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 311.0
EH2_k127_3203479_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
EH2_k127_3203479_2 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004427 260.0
EH2_k127_3203479_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000604 251.0
EH2_k127_3203479_4 Binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000545 147.0
EH2_k127_3203479_5 - - - - 0.000000000000000000000000000001623 129.0
EH2_k127_3203479_6 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000009533 74.0
EH2_k127_3203479_7 competence protein - - - 0.0000000007082 63.0
EH2_k127_3203479_8 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000005839 63.0
EH2_k127_320679_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000001524 160.0
EH2_k127_320679_1 membrane K08971 - - 0.00000000000000000000000000006912 132.0
EH2_k127_320679_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000000005296 105.0
EH2_k127_3211726_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 451.0
EH2_k127_3211726_1 Fe-S cluster K04488 - - 0.000000000000000000000000000000000000000000000000001656 193.0
EH2_k127_3211726_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000105 121.0
EH2_k127_3211726_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001367 118.0
EH2_k127_3211726_4 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000006239 113.0
EH2_k127_3211726_5 - - - - 0.00000000000001667 82.0
EH2_k127_3214150_0 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.00000000000000000000000000000000001616 157.0
EH2_k127_3221337_0 domain, Protein - - - 0.000000000004069 80.0
EH2_k127_3221337_1 Belongs to the glycosyl hydrolase family 6 - - - 0.0002591 54.0
EH2_k127_3236426_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 329.0
EH2_k127_3236426_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.00000000007907 75.0
EH2_k127_3237138_0 Methyltransferase - - - 0.0000000000000000000000005395 112.0
EH2_k127_3237138_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00001641 56.0
EH2_k127_3260745_0 Transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000001128 158.0
EH2_k127_3274594_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 304.0
EH2_k127_3281634_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000006038 138.0
EH2_k127_3281634_1 metallopeptidase activity - - - 0.000000000000000001024 102.0
EH2_k127_328848_0 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 398.0
EH2_k127_328848_1 Peptidase family M20/M25/M40 K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000001015 231.0
EH2_k127_3289199_0 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000000004427 213.0
EH2_k127_3289199_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000007684 229.0
EH2_k127_3290727_0 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K02557,K03286 - - 0.000000415 62.0
EH2_k127_3303716_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 395.0
EH2_k127_3303716_1 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000182 256.0
EH2_k127_3303716_2 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000002515 222.0
EH2_k127_3303716_3 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004053 233.0
EH2_k127_3303716_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000001823 171.0
EH2_k127_3303716_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000003659 138.0
EH2_k127_3303716_6 Ribosomal protein L23 K02892 - - 0.000000000000003766 78.0
EH2_k127_3303716_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000002823 52.0
EH2_k127_3308717_0 Polysaccharide biosynthesis protein CapD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 379.0
EH2_k127_3308717_1 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 301.0
EH2_k127_3308717_2 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.0000000000000000002646 91.0
EH2_k127_3308717_4 Glycosyl transferase, family 2 K07011 - - 0.0000000001656 73.0
EH2_k127_3312157_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.042e-283 895.0
EH2_k127_3312157_1 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 308.0
EH2_k127_3312157_2 Phospholipase_D-nuclease N-terminal - - - 0.00005558 55.0
EH2_k127_3330555_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.608e-241 763.0
EH2_k127_3330555_1 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.00000000000000000000000000000000001936 156.0
EH2_k127_3338539_0 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000004052 115.0
EH2_k127_3338539_1 phosphoesterase, PA-phosphatase related - - - 0.000000000004494 74.0
EH2_k127_3348103_0 Rad51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000278 243.0
EH2_k127_3348103_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000002512 135.0
EH2_k127_3364550_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 483.0
EH2_k127_3364550_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000152 200.0
EH2_k127_3364550_2 Pfam:DUF552 K09152 - - 0.000000000000004839 80.0
EH2_k127_3364550_3 - - - - 0.00002869 54.0
EH2_k127_3403497_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000005408 126.0
EH2_k127_3403497_1 carboxypeptidase K05996 - 3.4.17.18 0.0000000000000000000000003508 120.0
EH2_k127_3403497_2 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000994 83.0
EH2_k127_3430122_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 1.154e-194 631.0
EH2_k127_3430122_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 310.0
EH2_k127_3430122_2 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.00000000000000000000000000000000000000000000000000000000000004269 226.0
EH2_k127_3430122_3 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000001984 220.0
EH2_k127_3430122_4 PFAM Fibronectin type III domain - - - 0.00000006468 64.0
EH2_k127_3434496_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 506.0
EH2_k127_3434496_1 Putative DNA-binding domain K03655 - 3.6.4.12 0.00000001887 58.0
EH2_k127_3435682_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 563.0
EH2_k127_3435682_1 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 527.0
EH2_k127_3435682_2 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000339 232.0
EH2_k127_3435682_3 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000001441 216.0
EH2_k127_3435682_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000004125 192.0
EH2_k127_3442585_0 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 372.0
EH2_k127_3442585_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000002503 189.0
EH2_k127_3445630_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000433 99.0
EH2_k127_3477435_0 RNase_H superfamily K07502 - - 0.0000000000000000001108 95.0
EH2_k127_3477435_1 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.0000000001439 75.0
EH2_k127_3477435_2 Immunoglobulin K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.0007619 53.0
EH2_k127_3480949_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 372.0
EH2_k127_3480949_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000004183 201.0
EH2_k127_3480949_2 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000001468 200.0
EH2_k127_3480949_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins K01179,K01216,K02014,K07004,K15125,K16087,K21449 - 3.2.1.4,3.2.1.73 0.0000000000000000000000000000001189 141.0
EH2_k127_3480949_4 Putative small multi-drug export protein - - - 0.0000000006386 69.0
EH2_k127_3483623_0 PFAM PilT protein domain protein K06865 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 424.0
EH2_k127_3483623_1 COG0675 Transposase and inactivated derivatives K07496 - - 0.0000000000000000000000000761 111.0
EH2_k127_3483623_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000004805 104.0
EH2_k127_3495528_0 ATPases associated with a variety of cellular activities K02074 - - 0.00000000000000000000000000000000000000000000000000000009119 204.0
EH2_k127_3495528_1 ABC 3 transport family K09816,K09819 - - 0.000000000000000000000000000000000000002423 158.0
EH2_k127_3495528_2 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000438 138.0
EH2_k127_3495528_3 - - - - 0.000000000000000000000002974 104.0
EH2_k127_3495528_4 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000002196 86.0
EH2_k127_3495528_5 formylmethanofuran dehydrogenase, subunit E - - - 0.000000000000000004948 93.0
EH2_k127_3495946_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000001319 64.0
EH2_k127_3564823_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 294.0
EH2_k127_3564823_1 sulfate ABC transporter K02046 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 - 0.0000000000000000000015 98.0
EH2_k127_3584970_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 312.0
EH2_k127_3584970_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000005713 53.0
EH2_k127_3588037_0 cellulase activity K01083,K01224,K07004,K07156 - 3.1.3.8,3.2.1.89 0.000008471 59.0
EH2_k127_3588037_1 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0001933 51.0
EH2_k127_3596480_0 Fibronectin type III domain K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000007788 197.0
EH2_k127_3600737_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 360.0
EH2_k127_3600737_1 protein conserved in archaea - - - 0.0000000000000068 87.0
EH2_k127_3601051_0 Domain of unknown function - - - 0.0000000000000007158 94.0
EH2_k127_3601051_1 Fibronectin type 3 domain - - - 0.0000000000003447 85.0
EH2_k127_3614433_0 exo-alpha-(2->6)-sialidase activity - - - 0.0001423 54.0
EH2_k127_3629881_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 516.0
EH2_k127_3637071_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000001018 112.0
EH2_k127_3637071_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.000000001077 60.0
EH2_k127_3682011_0 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001087 261.0
EH2_k127_3682011_1 Fibronectin type 3 domain - - - 0.0000000000000000000000000003211 134.0
EH2_k127_3682011_2 self proteolysis K07114 - - 0.0000000000008817 84.0
EH2_k127_3682011_3 Belongs to the ompA family K20276 - - 0.00000000001213 79.0
EH2_k127_3682011_4 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000003019 74.0
EH2_k127_3682603_0 helicase superfamily c-terminal domain K03724 - - 1.01e-238 769.0
EH2_k127_3682603_1 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 337.0
EH2_k127_3682603_2 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000000001906 164.0
EH2_k127_3682603_3 TPR Domain containing protein - - - 0.000000000000000000000000000000003047 135.0
EH2_k127_3686056_0 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 389.0
EH2_k127_3686056_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000495 143.0
EH2_k127_3686056_2 Subtilase family K17734 - - 0.0000000000000000000000000000000003316 146.0
EH2_k127_3686056_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000003999 123.0
EH2_k127_3686056_4 response regulator, receiver K03413 - - 0.0000000000000006929 90.0
EH2_k127_3686056_5 Pas domain - - - 0.00005068 54.0
EH2_k127_3688793_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 582.0
EH2_k127_3690132_0 PFAM PKD domain containing protein - - - 0.000000000000000000002188 111.0
EH2_k127_3692910_0 SMART Tetratricopeptide - - - 0.0000002133 62.0
EH2_k127_3692910_1 protein conserved in archaea - - - 0.000000579 59.0
EH2_k127_3729411_0 Squalene--hopene cyclase K17811 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 5.5.1.16 0.0000000000000000000000000000000000000007448 166.0
EH2_k127_3729411_1 transferase activity, transferring alkyl or aryl (other than methyl) groups - - - 0.00000000008702 73.0
EH2_k127_3729411_2 Protein of unknown function (DUF835) - - - 0.000003418 60.0
EH2_k127_3742947_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.422e-259 814.0
EH2_k127_3742947_1 COG3325 Chitinase K01183 - 3.2.1.14 0.0000786 55.0
EH2_k127_3751373_0 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.901e-238 760.0
EH2_k127_3751373_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.000000000000000000000000000000000001257 141.0
EH2_k127_3751373_2 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000004881 75.0
EH2_k127_3766106_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.737e-226 713.0
EH2_k127_3766106_1 Transcriptional regulator K07722 - - 0.000001276 57.0
EH2_k127_3795428_0 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000001369 256.0
EH2_k127_3795428_1 archaeal coiled-coil protein - - - 0.00000000000000000001015 107.0
EH2_k127_3795428_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000002799 57.0
EH2_k127_3808715_0 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001108 247.0
EH2_k127_3808715_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000009656 199.0
EH2_k127_3808715_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000001715 176.0
EH2_k127_3810918_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003826 284.0
EH2_k127_3810918_1 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000004064 98.0
EH2_k127_3810918_2 Alpha beta hydrolase - - - 0.000007653 50.0
EH2_k127_3831511_0 PFAM Ig domain protein group 2 domain protein - - - 0.0000000007258 65.0
EH2_k127_3834848_0 HELICc2 K03722,K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 437.0
EH2_k127_3834848_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 376.0
EH2_k127_3834848_2 - - - - 0.00000000000000000000000000000000000000188 151.0
EH2_k127_3834848_3 vitamin K biosynthetic process - - - 0.000000000000000000000000000000004608 143.0
EH2_k127_3834848_4 Flavodoxin - - - 0.0000000000000000000000000000001886 129.0
EH2_k127_3834848_5 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000276 71.0
EH2_k127_3837392_0 RmlD substrate binding domain K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 444.0
EH2_k127_3837392_1 Serine aminopeptidase, S33 - - - 0.000000001073 65.0
EH2_k127_3839805_0 AAA domain, putative AbiEii toxin, Type IV TA system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000007242 201.0
EH2_k127_3839805_1 CcmB protein K02194 - - 0.00000000000000000000000000005755 128.0
EH2_k127_3839805_2 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.000000000000002003 84.0
EH2_k127_3857366_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000002372 152.0
EH2_k127_3857366_1 Bacterial Ig-like domain (group 3) K20276 - - 0.0000000000000003227 94.0
EH2_k127_3898529_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000007725 199.0
EH2_k127_3929999_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 362.0
EH2_k127_3948449_0 domain, Protein K01218,K10953,K12516,K15125,K19231 - 3.2.1.78 0.00008696 56.0
EH2_k127_3958985_0 radical SAM domain protein K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003874 292.0
EH2_k127_3958985_1 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005429 252.0
EH2_k127_3958985_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000001178 156.0
EH2_k127_3958985_4 metallopeptidase activity - - - 0.000000000009038 80.0
EH2_k127_3958985_5 PFAM Methyltransferase type - - - 0.0001574 51.0
EH2_k127_3959513_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 366.0
EH2_k127_3959513_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 326.0
EH2_k127_3959513_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000007861 97.0
EH2_k127_3996471_0 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000006542 197.0
EH2_k127_3996471_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000001184 106.0
EH2_k127_3996471_2 endoribonuclease L-PSP - - - 0.000393 48.0
EH2_k127_4012297_0 MCM OB domain K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 621.0
EH2_k127_4025563_0 PKD domain containing protein - - - 0.000000000001243 81.0
EH2_k127_4034573_0 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.0000000000000000000000000000000004624 149.0
EH2_k127_4034573_1 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K02557,K03286 - - 0.0003856 53.0
EH2_k127_4037957_0 Bifunctional pyrimidine biosynthesis protein (PyrABCN) K01954,K11541 GO:0000050,GO:0003674,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009892,GO:0009987,GO:0016020,GO:0016021,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019219,GO:0019222,GO:0019627,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045934,GO:0045984,GO:0046112,GO:0046394,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0055086,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0080090,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.2,6.3.5.5 3.321e-271 857.0
EH2_k127_4037957_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000195 153.0
EH2_k127_4043278_0 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000004114 178.0
EH2_k127_4043278_1 Predicted membrane protein (DUF2085) - - - 0.000000000001575 72.0
EH2_k127_4043278_2 TonB dependent receptor K02014,K16087 - - 0.00006518 54.0
EH2_k127_4044390_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000009455 93.0
EH2_k127_4044390_1 Acetyltransferase (GNAT) domain - - - 0.0006818 51.0
EH2_k127_4045669_0 TIGRFAM acetylornithine deacetylase or K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 387.0
EH2_k127_4045669_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 289.0
EH2_k127_4045669_2 - - - - 0.0000000000000000000000000000000000000002535 162.0
EH2_k127_4045669_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000004248 156.0
EH2_k127_4045669_4 AMMECR1 K09141 - - 0.0000000000000000000000000004437 115.0
EH2_k127_4059766_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000001431 248.0
EH2_k127_4059766_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000004903 121.0
EH2_k127_4059778_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1023.0
EH2_k127_4059778_1 helicase superfamily c-terminal domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 471.0
EH2_k127_4059778_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
EH2_k127_4059778_3 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000003952 208.0
EH2_k127_4059778_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000000000001184 185.0
EH2_k127_4059778_5 Translin family K07477 - - 0.0000000000000000000000000000006758 131.0
EH2_k127_4068190_0 domain, Protein - - - 0.00000000000134 81.0
EH2_k127_4073600_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 403.0
EH2_k127_4073600_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 306.0
EH2_k127_4073600_2 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000000003869 96.0
EH2_k127_4073600_3 Participates in transcription termination K02600 - - 0.00000000000000000001293 97.0
EH2_k127_4073600_4 PFAM PKD domain containing protein - - - 0.00000002173 59.0
EH2_k127_4097358_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 324.0
EH2_k127_4097358_1 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000001493 78.0
EH2_k127_4101160_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 451.0
EH2_k127_4101160_1 endonuclease III K07457 - - 0.0000000000000000004776 89.0
EH2_k127_4101160_2 KaiC - - - 0.000000000002894 76.0
EH2_k127_4101160_3 CARDB - - - 0.00000004899 67.0
EH2_k127_4101160_4 Immune inhibitor A peptidase M6 - - - 0.00000008504 66.0
EH2_k127_4113232_0 PFAM Uncharacterised protein family UPF0016 - - - 0.000000000000000000273 95.0
EH2_k127_4120530_0 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000002313 70.0
EH2_k127_4120530_1 Bacterial PH domain - - - 0.0003218 53.0
EH2_k127_4152636_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 345.0
EH2_k127_421222_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 346.0
EH2_k127_421222_1 ATP-grasp domain K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 327.0
EH2_k127_421222_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000451 138.0
EH2_k127_421222_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000003479 70.0
EH2_k127_421222_4 protein contain chitin-binding domain type 3 - - - 0.00000007707 64.0
EH2_k127_421222_5 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000001504 53.0
EH2_k127_4213996_0 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000001807 214.0
EH2_k127_4213996_1 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.000000000000000000000000000000000000000000001368 177.0
EH2_k127_4213996_2 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000002661 174.0
EH2_k127_4213996_3 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000005568 149.0
EH2_k127_4221493_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001545 247.0
EH2_k127_4225195_0 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001335 231.0
EH2_k127_4225195_1 Molybdopterin oxidoreductase - - - 0.0000000000000000000000000000000000005273 158.0
EH2_k127_4225195_2 component of anaerobic - - - 0.0000000000001972 82.0
EH2_k127_4232844_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 618.0
EH2_k127_4232844_1 Thioredoxin-like K06196 - - 0.0000000000001878 80.0
EH2_k127_4232844_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000003537 77.0
EH2_k127_4232844_3 - - - - 0.000004162 58.0
EH2_k127_423325_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000145 282.0
EH2_k127_423325_1 Serine threonine protein kinase - - - 0.0000000000000000000000000000000003619 152.0
EH2_k127_423325_2 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000001677 68.0
EH2_k127_4239227_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004638 245.0
EH2_k127_4240180_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 449.0
EH2_k127_4240180_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000003904 123.0
EH2_k127_4250280_0 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 420.0
EH2_k127_4250280_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 302.0
EH2_k127_4258920_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001573 267.0
EH2_k127_4258920_1 chromatin organization - - - 0.000000000000000000896 96.0
EH2_k127_4263857_0 Fibronectin type 3 domain - - - 0.00000001876 69.0
EH2_k127_4273768_0 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000000000000000000001353 145.0
EH2_k127_4273768_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000004021 135.0
EH2_k127_4273768_2 Putative Phosphatase - - - 0.000000000000000000000000000000005902 136.0
EH2_k127_4273768_3 Domain of unknown function (DU1801) - - - 0.0000026 52.0
EH2_k127_4273768_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000002708 60.0
EH2_k127_4275828_0 chlorophyll binding - - - 0.000000000000000000000001392 121.0
EH2_k127_4291820_0 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000000000000107 187.0
EH2_k127_4291820_1 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000009107 156.0
EH2_k127_4294597_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0001969 55.0
EH2_k127_4302622_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 357.0
EH2_k127_4302622_1 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000001136 209.0
EH2_k127_4302622_2 PFAM WD40 repeat, subgroup - - - 0.000000000000000000000000000001084 133.0
EH2_k127_4302622_3 peptidase activity, acting on L-amino acid peptides K20276 - - 0.000000000000000004452 101.0
EH2_k127_4303273_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 391.0
EH2_k127_4303273_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 317.0
EH2_k127_4306785_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000005822 262.0
EH2_k127_4306785_1 COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair - - - 0.0000003269 53.0
EH2_k127_4327314_0 COG1361 S-layer domain - - - 0.0004597 53.0
EH2_k127_4350373_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000004401 91.0
EH2_k127_4373082_0 PFAM PKD domain containing protein - - - 0.0000253 57.0
EH2_k127_4404379_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 394.0
EH2_k127_4404379_1 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000000000000003373 130.0
EH2_k127_4404379_2 Glycosyl transferases group 1 K12989 - - 0.000000000000000000001626 99.0
EH2_k127_4410366_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 525.0
EH2_k127_4410366_1 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001512 268.0
EH2_k127_4419294_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 363.0
EH2_k127_4419294_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 351.0
EH2_k127_4419294_2 protein conserved in archaea - - - 0.0000001673 64.0
EH2_k127_4419294_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00003852 47.0
EH2_k127_4426159_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 535.0
EH2_k127_4426159_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.0001911 49.0
EH2_k127_4437974_0 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.0000000000000000000000000008555 132.0
EH2_k127_4437974_1 PFAM tRNA synthetase class II (D K and N), nucleic acid binding OB-fold tRNA helicase-type K01893 - 6.1.1.22 0.0000000008333 64.0
EH2_k127_4443161_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000002851 102.0
EH2_k127_4443161_1 SMART Elongator protein 3 MiaB NifB K06935,K06941 - 2.1.1.192 0.000000000000000001161 97.0
EH2_k127_4443161_2 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000257 53.0
EH2_k127_4444867_0 myosin light chain kinase activity K12567 - 2.7.11.1 0.00000000000000000000284 106.0
EH2_k127_4448184_0 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000001983 138.0
EH2_k127_4448184_1 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000000000003823 125.0
EH2_k127_4448184_2 domain protein K20276 - - 0.000000000001099 82.0
EH2_k127_4448184_3 Cadherin repeats. - - - 0.00000783 61.0
EH2_k127_4492685_0 Tetratricopeptide repeats - - - 0.00001312 59.0
EH2_k127_4492685_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00002911 58.0
EH2_k127_4498047_0 PFAM amidohydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 369.0
EH2_k127_4498047_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001552 282.0
EH2_k127_4498047_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000007659 239.0
EH2_k127_4521224_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 419.0
EH2_k127_4521224_1 Serine protease with a broad substrate specificity K13276,K17734 - - 0.00000000000000000000000000000000000000006066 172.0
EH2_k127_4521224_2 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000001607 129.0
EH2_k127_4521224_3 archaeal coiled-coil protein - - - 0.000000000000000000004717 105.0
EH2_k127_4521224_4 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.00000000000000000003594 97.0
EH2_k127_4521224_5 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.0000002249 60.0
EH2_k127_4535990_0 PKD domain - - - 0.00000000000000588 90.0
EH2_k127_4535990_1 Kelch motif - - - 0.0000004716 64.0
EH2_k127_4546311_0 Potassium uptake protein, TrkH family K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 337.0
EH2_k127_4565321_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 416.0
EH2_k127_4565321_1 - - - - 0.000000000000000000000000000000000000000000000142 189.0
EH2_k127_4565321_2 Dodecin K09165 - - 0.000000000002109 74.0
EH2_k127_4565321_3 - - - - 0.0000001389 61.0
EH2_k127_4571885_0 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000000000000000000000001861 169.0
EH2_k127_4619254_0 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 322.0
EH2_k127_4619254_1 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.000000000000000000000000000000000000001412 156.0
EH2_k127_4619254_2 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.000000000000000000000000000000000000002932 148.0
EH2_k127_4619254_3 HEPN domain - - - 0.000000000000000000000000001587 117.0
EH2_k127_4619254_4 Nucleotidyltransferase domain K07076 - - 0.00006325 49.0
EH2_k127_4622506_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000694 55.0
EH2_k127_4636580_0 Aromatic amino acid lyase K01745 - 4.3.1.3 3.868e-245 766.0
EH2_k127_4636580_1 Carboxyl transferase domain - - - 2.324e-232 731.0
EH2_k127_4636580_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 525.0
EH2_k127_4636580_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 299.0
EH2_k127_4636580_4 Biotin-requiring enzyme K02160 - - 0.00000000000000000002653 91.0
EH2_k127_4644949_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 304.0
EH2_k127_4644949_1 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000002144 191.0
EH2_k127_4644949_2 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000003914 159.0
EH2_k127_4644949_3 Integral membrane protein DUF106 - - - 0.00000000000000000000008485 107.0
EH2_k127_4659486_0 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000361 215.0
EH2_k127_4659486_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000002338 201.0
EH2_k127_4659486_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000009447 65.0
EH2_k127_4659486_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000002415 184.0
EH2_k127_4659486_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000006243 185.0
EH2_k127_4659486_4 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002553 141.0
EH2_k127_4659486_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000001965 121.0
EH2_k127_4659486_6 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002005 109.0
EH2_k127_4659486_7 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000004549 101.0
EH2_k127_4659486_8 ribosomal protein S14 K02954 - - 0.00000000000000000007383 90.0
EH2_k127_4659486_9 Ribosomal L29 protein K02904 - - 0.00000000000009133 72.0
EH2_k127_4663982_0 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001402 218.0
EH2_k127_4663982_1 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000001256 184.0
EH2_k127_4678176_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 407.0
EH2_k127_4678176_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000005627 179.0
EH2_k127_4678176_2 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.0000000000000000000000000000000003507 147.0
EH2_k127_4678176_3 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen K00503 GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004500,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006066,GO:0006576,GO:0006584,GO:0006589,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009308,GO:0009309,GO:0009712,GO:0009713,GO:0009987,GO:0012505,GO:0012506,GO:0016020,GO:0016491,GO:0016705,GO:0016715,GO:0017144,GO:0018958,GO:0019336,GO:0019438,GO:0019439,GO:0019614,GO:0030141,GO:0030659,GO:0030667,GO:0031090,GO:0031410,GO:0031982,GO:0031984,GO:0034641,GO:0042133,GO:0042136,GO:0042175,GO:0042401,GO:0042415,GO:0042417,GO:0042420,GO:0042421,GO:0042423,GO:0042424,GO:0042439,GO:0042737,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044106,GO:0044237,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046189,GO:0046333,GO:0046872,GO:0046914,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:0097708,GO:0098588,GO:0098805,GO:0098827,GO:0099503,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617 1.14.17.1 0.0007422 51.0
EH2_k127_4689485_0 glycoside hydrolase, family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 512.0
EH2_k127_4705292_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 340.0
EH2_k127_4705292_1 Helix-hairpin-helix motif K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000001366 229.0
EH2_k127_4705292_2 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000539 178.0
EH2_k127_4705292_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000002728 108.0
EH2_k127_4705292_4 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000005041 78.0
EH2_k127_4707426_0 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000006991 208.0
EH2_k127_4713764_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000001108 171.0
EH2_k127_4713764_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000004875 126.0
EH2_k127_4713764_2 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.0000000000001982 75.0
EH2_k127_4713764_3 FtsX-like permease family K02004 - - 0.00000001247 68.0
EH2_k127_4713764_4 - - - - 0.00000008338 66.0
EH2_k127_4754719_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 336.0
EH2_k127_4754719_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000001578 168.0
EH2_k127_4754719_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000007391 163.0
EH2_k127_4754719_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000003409 115.0
EH2_k127_475576_0 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000004517 235.0
EH2_k127_475576_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000001744 215.0
EH2_k127_475576_2 monooxygenase activity - - - 0.0000000005131 65.0
EH2_k127_4760571_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000002823 232.0
EH2_k127_4771328_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 382.0
EH2_k127_4771328_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 352.0
EH2_k127_4771328_2 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000002196 224.0
EH2_k127_4771328_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000002366 207.0
EH2_k127_4771328_4 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000003993 162.0
EH2_k127_4785789_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 340.0
EH2_k127_4788244_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 350.0
EH2_k127_4788244_1 ATPase activity K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000001462 235.0
EH2_k127_4788244_2 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000001105 155.0
EH2_k127_4788244_3 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000002137 149.0
EH2_k127_4788244_4 ABC-2 family transporter protein K01992 - - 0.0000000005872 69.0
EH2_k127_4796665_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 372.0
EH2_k127_4796665_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 335.0
EH2_k127_4796665_2 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000001911 76.0
EH2_k127_4807258_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 432.0
EH2_k127_4807258_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 388.0
EH2_k127_4807258_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000002764 216.0
EH2_k127_4807258_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000003537 188.0
EH2_k127_4807258_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000002989 109.0
EH2_k127_4807258_5 Protein of unknown function (DUF835) - - - 0.00000000007909 69.0
EH2_k127_4838100_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 375.0
EH2_k127_4838100_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000001986 171.0
EH2_k127_4838100_2 PFAM 4Fe-4S binding domain - - - 0.0000000003595 61.0
EH2_k127_4889671_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000001602 215.0
EH2_k127_4889671_1 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000001191 177.0
EH2_k127_4889671_2 domain protein - - - 0.0000000000000000000000006706 113.0
EH2_k127_4889856_0 PFAM NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 532.0
EH2_k127_4901395_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004578 252.0
EH2_k127_4919717_0 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000002281 234.0
EH2_k127_4942809_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.543e-291 908.0
EH2_k127_4942809_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 5.489e-246 774.0
EH2_k127_4946927_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.29e-281 893.0
EH2_k127_4946927_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465,K01466 - 3.5.2.3,3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008336 281.0
EH2_k127_4946927_2 Protein of unknown function (DUF402) K09145 - - 0.000000000000000007197 91.0
EH2_k127_4953812_0 Putative TM nitroreductase - - - 0.000000000000000000000000000002157 132.0
EH2_k127_4953812_1 flavin reductase - - - 0.000000000000000000000000002241 122.0
EH2_k127_4953812_2 alginic acid biosynthetic process - - - 0.000000000000000000000000004379 130.0
EH2_k127_4953812_3 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.0000000000000000000000002262 123.0
EH2_k127_4960857_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000733 207.0
EH2_k127_4960857_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000009141 204.0
EH2_k127_5003601_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000009977 148.0
EH2_k127_5003601_1 NADPH-dependent FMN reductase - - - 0.000000000000004033 79.0
EH2_k127_5022182_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000001005 147.0
EH2_k127_5022182_1 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.0000000000000000001183 100.0
EH2_k127_5022182_2 OsmC-like protein - - - 0.0003244 48.0
EH2_k127_5026311_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 556.0
EH2_k127_5026311_1 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000009623 185.0
EH2_k127_5026311_2 Glycosyl transferase 4-like - - - 0.00000000000000000000008978 112.0
EH2_k127_5026311_3 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000001298 89.0
EH2_k127_5032319_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 298.0
EH2_k127_5032319_1 4Fe-4S dicluster domain - - - 0.0000000000000000000004438 102.0
EH2_k127_5037124_0 Pro-kumamolisin, activation domain - - - 0.0000002719 64.0
EH2_k127_5042645_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 346.0
EH2_k127_5042645_1 isomerase K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000001579 210.0
EH2_k127_5042645_2 Polynucleotide kinase 3 phosphatase - - - 0.00000000000000003305 87.0
EH2_k127_5044071_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 477.0
EH2_k127_5053581_0 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.0000000000000000000000000001138 135.0
EH2_k127_5053581_1 Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase chloroplastic K13832 - 1.1.1.25,4.2.1.10 0.00003872 54.0
EH2_k127_5070300_0 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000017 145.0
EH2_k127_5070300_1 ATPase activator activity - GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008047,GO:0008150,GO:0009987,GO:0030234,GO:0031072,GO:0032781,GO:0043085,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051087,GO:0051336,GO:0051345,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000001496 78.0
EH2_k127_5077909_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000007068 198.0
EH2_k127_5077909_1 geranylgeranyl reductase K21401 - 1.3.99.38 0.00006949 48.0
EH2_k127_5077953_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.317e-258 842.0
EH2_k127_5077953_1 PFAM TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001796 274.0
EH2_k127_5077953_2 Zinc finger domain K04043 - - 0.00000003485 67.0
EH2_k127_5077953_3 PFAM TPR repeat-containing protein - - - 0.000002878 61.0
EH2_k127_5109302_0 Mechanosensitive ion channel K03442,K05802,K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 244.0
EH2_k127_5121578_0 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.00000000002094 77.0
EH2_k127_5131872_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000008024 150.0
EH2_k127_5131872_1 domain protein - - - 0.0000000001391 71.0
EH2_k127_5139199_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 495.0
EH2_k127_5139199_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000003385 194.0
EH2_k127_51458_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 523.0
EH2_k127_51458_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 362.0
EH2_k127_51458_2 Double zinc ribbon - - - 0.0000000003187 75.0
EH2_k127_51458_3 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000002167 58.0
EH2_k127_516829_0 metal ion binding. It is involved in the biological process described with protein ubiquitination K10595 GO:0000003,GO:0000726,GO:0003674,GO:0003824,GO:0004842,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005814,GO:0005815,GO:0005856,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006974,GO:0007276,GO:0007283,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0015031,GO:0015630,GO:0015833,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0019953,GO:0022414,GO:0030163,GO:0031625,GO:0031974,GO:0031981,GO:0032182,GO:0032183,GO:0032446,GO:0032501,GO:0032504,GO:0033036,GO:0033554,GO:0034613,GO:0034641,GO:0036211,GO:0042886,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044703,GO:0045184,GO:0046483,GO:0046907,GO:0048232,GO:0048609,GO:0050896,GO:0051020,GO:0051179,GO:0051234,GO:0051603,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0061630,GO:0061659,GO:0065007,GO:0065009,GO:0070013,GO:0070647,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0098772,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575 2.3.2.26 0.000003886 60.0
EH2_k127_5180566_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 454.0
EH2_k127_5180566_1 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 456.0
EH2_k127_5180566_2 Glucose inhibited division protein A K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 383.0
EH2_k127_5180566_3 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 357.0
EH2_k127_5180566_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000002443 211.0
EH2_k127_5180566_5 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000000000000000000001129 122.0
EH2_k127_5180566_6 Protein of unknown function DUF86 - - - 0.00000000000000000000000000003039 121.0
EH2_k127_5180566_7 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000006536 115.0
EH2_k127_5193423_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000011 203.0
EH2_k127_5193423_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000008536 204.0
EH2_k127_5193423_2 PFAM Sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000005406 124.0
EH2_k127_5202058_0 Belongs to the peptidase S8 family - - - 0.0000007073 63.0
EH2_k127_5211549_0 OmpA family - - - 0.00000000000118 83.0
EH2_k127_5234146_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 6.765e-194 621.0
EH2_k127_5234146_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000009151 262.0
EH2_k127_5234146_2 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000000000002814 217.0
EH2_k127_5234146_3 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000004354 189.0
EH2_k127_5234146_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000003627 177.0
EH2_k127_5234146_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.00000000000000000001776 100.0
EH2_k127_5234146_6 Transcriptional regulator, AbiEi antitoxin - - - 0.000000000000001106 86.0
EH2_k127_5234146_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000009363 58.0
EH2_k127_5234146_8 EamA-like transporter family K15268 - - 0.00003435 52.0
EH2_k127_5234146_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K03298 - - 0.0003573 48.0
EH2_k127_5236288_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005271 273.0
EH2_k127_5236288_1 Fibronectin type 3 domain K12567,K14721 - 2.7.11.1 0.000000000000000007219 100.0
EH2_k127_5240552_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001505 291.0
EH2_k127_5240552_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000007738 208.0
EH2_k127_5240552_2 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000717 152.0
EH2_k127_5240552_3 Histidine kinase - - - 0.000000000006125 80.0
EH2_k127_5240552_4 Double zinc ribbon - - - 0.000002521 58.0
EH2_k127_5240552_5 iron dependent repressor - - - 0.00005822 56.0
EH2_k127_5245838_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 528.0
EH2_k127_5245838_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000008925 108.0
EH2_k127_5247439_0 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000116 281.0
EH2_k127_5247439_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.00000000003411 75.0
EH2_k127_5247439_2 Reeler domain - - - 0.00001923 57.0
EH2_k127_5253385_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000002866 239.0
EH2_k127_5253385_1 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000000001403 188.0
EH2_k127_5255742_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 1.403e-197 622.0
EH2_k127_5255742_1 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 421.0
EH2_k127_5271483_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000003607 93.0
EH2_k127_5271483_1 - - - - 0.00000009441 61.0
EH2_k127_5271483_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0006809 53.0
EH2_k127_5276104_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.451e-240 752.0
EH2_k127_5276104_1 Oxaloacetate decarboxylase K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 366.0
EH2_k127_5276385_0 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 313.0
EH2_k127_5276385_1 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 300.0
EH2_k127_5276385_2 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000004943 158.0
EH2_k127_5276385_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000005887 144.0
EH2_k127_5331554_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 366.0
EH2_k127_5331554_1 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000009199 205.0
EH2_k127_5358826_0 protein conserved in archaea - - - 0.000000000251 73.0
EH2_k127_5379279_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000007829 88.0
EH2_k127_5386226_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000004229 57.0
EH2_k127_5399928_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 385.0
EH2_k127_5399928_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000004835 92.0
EH2_k127_5400737_0 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000001725 249.0
EH2_k127_5400737_1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00003924 55.0
EH2_k127_5400737_2 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0001942 53.0
EH2_k127_5406044_0 Belongs to the peptidase S8 family - - - 0.0001957 54.0
EH2_k127_5414904_1 zinc ion binding - - - 0.00001424 59.0
EH2_k127_5414904_2 peptidase activity, acting on L-amino acid peptides K02035 - - 0.00003593 53.0
EH2_k127_5433682_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000005011 135.0
EH2_k127_5433682_1 Belongs to the UPF0248 family K09715 - - 0.00001575 55.0
EH2_k127_543416_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000002322 206.0
EH2_k127_543416_1 Transcriptional regulator, TrmB - - - 0.0000000000004391 72.0
EH2_k127_543416_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0001854 53.0
EH2_k127_5445164_0 KH domain K07041 - - 1.301e-249 803.0
EH2_k127_5445164_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000001754 227.0
EH2_k127_5457929_0 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.000000000000000000000000000000000000000000000000000000001406 207.0
EH2_k127_5457929_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000002466 197.0
EH2_k127_5477921_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 413.0
EH2_k127_5477921_1 TraB family - - - 0.0000000000000000000000000000009216 131.0
EH2_k127_5477921_2 Subtilase family - - - 0.0000000000000000006827 94.0
EH2_k127_5495050_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 604.0
EH2_k127_5495050_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001844 254.0
EH2_k127_5495050_10 Pfam:DUF1628 - - - 0.00006809 57.0
EH2_k127_5495050_2 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000001314 222.0
EH2_k127_5495050_3 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000616 202.0
EH2_k127_5495050_4 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000003272 129.0
EH2_k127_5495050_5 PKD domain - - - 0.00000000000000000000000008475 125.0
EH2_k127_5495050_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000001592 100.0
EH2_k127_5495050_7 acetyltransferase - - - 0.0000000000000000211 93.0
EH2_k127_5495050_8 PFAM PKD domain containing protein - - - 0.0000000000000007162 88.0
EH2_k127_5495050_9 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00005159 46.0
EH2_k127_553035_0 - - - - 0.00000000000000000000000000000000000000001577 173.0
EH2_k127_5552409_0 PFAM FecR protein - - - 0.000000001598 71.0
EH2_k127_5552409_1 polygalacturonase activity - - - 0.00005886 56.0
EH2_k127_5561870_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 557.0
EH2_k127_5561870_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001587 296.0
EH2_k127_5561870_2 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000001292 160.0
EH2_k127_5561870_3 Protein of unknown function DUF131 - - - 0.0000682 52.0
EH2_k127_5566649_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 598.0
EH2_k127_5566649_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 463.0
EH2_k127_5566649_2 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 383.0
EH2_k127_5566649_3 GTPase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 321.0
EH2_k127_5566649_4 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000001003 195.0
EH2_k127_5580047_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 385.0
EH2_k127_5580047_1 PKD domain containing protein - - - 0.00001751 57.0
EH2_k127_5583573_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009791 274.0
EH2_k127_5583573_1 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.00000000000000000000000000000002275 134.0
EH2_k127_5583573_2 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000009479 128.0
EH2_k127_5583573_3 Protein of unknown function (DUF1616) - - - 0.00000000000000009294 91.0
EH2_k127_5583612_0 cellulase activity K01183,K01728 - 3.2.1.14,4.2.2.2 0.00000000000000000000000000000000000000000000000000000000002238 231.0
EH2_k127_5586003_0 Ethylbenzene dehydrogenase - - - 0.0000000000000000000001928 115.0
EH2_k127_5586003_1 Ethylbenzene dehydrogenase - - - 0.0000000000000000002538 100.0
EH2_k127_5586003_2 CARDB - - - 0.0000000000003204 84.0
EH2_k127_5587532_0 antibiotic catabolic process - - - 0.000001157 62.0
EH2_k127_559712_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0002161,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 440.0
EH2_k127_5600900_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000001273 245.0
EH2_k127_5600900_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000001903 200.0
EH2_k127_5600900_2 - - - - 0.00000000000000000000000000112 119.0
EH2_k127_5600900_3 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000344 92.0
EH2_k127_5600900_4 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000807 79.0
EH2_k127_5600900_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000009194 83.0
EH2_k127_5603780_0 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004521 263.0
EH2_k127_5603780_1 CARDB - - - 0.0001502 53.0
EH2_k127_5606363_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 407.0
EH2_k127_5606363_1 PFAM acylneuraminate cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000007728 236.0
EH2_k127_5606363_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000183 209.0
EH2_k127_5606363_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000001035 201.0
EH2_k127_5606363_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000004177 181.0
EH2_k127_5616061_0 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000297 208.0
EH2_k127_5616061_1 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000005873 187.0
EH2_k127_5616061_2 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000004504 123.0
EH2_k127_5616061_3 PFAM glutaredoxin K06191 - - 0.000000000000000000008414 95.0
EH2_k127_5629487_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 310.0
EH2_k127_5629487_1 Transcriptional regulator - - - 0.00000000309 66.0
EH2_k127_5629487_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0001379 53.0
EH2_k127_5643351_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 400.0
EH2_k127_5643351_1 C-terminal domain of CHU protein family - - - 0.0002155 54.0
EH2_k127_5651706_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 377.0
EH2_k127_5655527_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 353.0
EH2_k127_5655527_1 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001853 265.0
EH2_k127_5655527_2 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000002083 96.0
EH2_k127_5655527_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000003633 92.0
EH2_k127_5655527_4 HemY domain protein - - - 0.00000000003654 73.0
EH2_k127_5655527_5 Transcriptional regulator - - - 0.00000005506 65.0
EH2_k127_5659581_0 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000005392 209.0
EH2_k127_5659581_1 scavenger receptor activity K21430 - - 0.00004984 51.0
EH2_k127_5680235_0 alginic acid biosynthetic process - - - 0.0000000000004012 83.0
EH2_k127_5683166_0 Toprim domain K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 419.0
EH2_k127_5683166_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000007688 93.0
EH2_k127_5720316_0 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000002323 89.0
EH2_k127_572941_0 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00003914 56.0
EH2_k127_5785581_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003081 280.0
EH2_k127_5785581_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 250.0
EH2_k127_5785581_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003903 199.0
EH2_k127_5785581_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000005688 183.0
EH2_k127_5785581_4 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000005903 169.0
EH2_k127_5785581_5 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000309 162.0
EH2_k127_5785581_6 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001206 149.0
EH2_k127_5785581_7 Binds to the 23S rRNA K02876 - - 0.0000000000000000000002871 102.0
EH2_k127_5791496_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000278 128.0
EH2_k127_5791496_1 PFAM response regulator receiver - - - 0.0000000000000009873 82.0
EH2_k127_5794744_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.00000000000000000000000000000000000000000000000000000000000000007251 234.0
EH2_k127_5794744_1 Ligand-binding protein SH3 - - - 0.00000000000000000000000001378 119.0
EH2_k127_5794744_2 Rhomboid family - - - 0.00000000000000001161 94.0
EH2_k127_5794744_3 - - - - 0.0007057 48.0
EH2_k127_5803423_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 304.0
EH2_k127_5803423_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000001266 85.0
EH2_k127_5804434_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 461.0
EH2_k127_5804434_1 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000002019 157.0
EH2_k127_5875201_0 Fibronectin type 3 domain - - - 0.00000000001516 78.0
EH2_k127_5878861_0 Tubulin like - - - 0.000000005969 72.0
EH2_k127_5878861_1 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.000005671 62.0
EH2_k127_5878861_2 PFAM Ubiquitin-conjugating - - - 0.000128 53.0
EH2_k127_5891089_0 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000186 222.0
EH2_k127_5891089_1 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000003279 164.0
EH2_k127_5891089_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000008043 123.0
EH2_k127_5899334_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 312.0
EH2_k127_5899334_1 Belongs to the ompA family K20276 - - 0.000000000000003071 91.0
EH2_k127_5899334_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000009872 82.0
EH2_k127_5899334_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000008559 67.0
EH2_k127_5899334_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000001782 66.0
EH2_k127_5942917_0 Hemerythrin HHE cation binding domain protein K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 377.0
EH2_k127_5942917_1 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000007945 153.0
EH2_k127_5942917_2 ADP-ribosylation Crystallin J1 - - - 0.00000000194 61.0
EH2_k127_5942917_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000004957 57.0
EH2_k127_5950671_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 359.0
EH2_k127_5950671_1 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 287.0
EH2_k127_5951847_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 319.0
EH2_k127_5951847_1 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000005484 187.0
EH2_k127_5951847_2 PFAM Tetratricopeptide - - - 0.000000000000002252 83.0
EH2_k127_5953461_0 COG3291 FOG PKD repeat - - - 0.00000000000000000000000000000000008013 152.0
EH2_k127_5986924_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 425.0
EH2_k127_5986924_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 394.0
EH2_k127_5986924_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000002261 164.0
EH2_k127_5986924_3 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0003695 55.0
EH2_k127_5989307_0 Belongs to the peptidase S8 family - - - 0.0000000000000000006121 103.0
EH2_k127_6002964_0 COG1290 Cytochrome b subunit of the bc complex - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004478 294.0
EH2_k127_6002964_1 Rieske 2Fe-2S - - - 0.000000000000001269 82.0
EH2_k127_6004147_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 338.0
EH2_k127_6004147_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 304.0
EH2_k127_6004147_2 Glycosyl transferase family 2 K09931 - - 0.0000000000000000000000000000000000000000000000000000001718 214.0
EH2_k127_6009951_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002948 225.0
EH2_k127_6009951_1 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.00000129 61.0
EH2_k127_6011882_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 359.0
EH2_k127_6011882_1 - - - - 0.0000001925 57.0
EH2_k127_601544_0 serine threonine protein kinase - - - 0.00000000000000000000000005982 121.0
EH2_k127_6024049_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000017 254.0
EH2_k127_6024049_1 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000005411 186.0
EH2_k127_6024049_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000001553 164.0
EH2_k127_6024049_3 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000001176 101.0
EH2_k127_6036034_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000003293 208.0
EH2_k127_6036034_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000006187 168.0
EH2_k127_6036034_2 TIGRFAM Bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.00000138 61.0
EH2_k127_6052616_0 Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 396.0
EH2_k127_6052616_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000007227 146.0
EH2_k127_6064088_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 535.0
EH2_k127_6064088_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 462.0
EH2_k127_6064088_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 449.0
EH2_k127_6064088_3 Subtilase family K17734 - - 0.0000000000000000000000000000000000379 153.0
EH2_k127_6064088_4 - - - - 0.0000000000000000005458 93.0
EH2_k127_6064088_5 - - - - 0.00000000000003864 79.0
EH2_k127_6064088_6 - - - - 0.0000026 52.0
EH2_k127_6065324_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000001776 232.0
EH2_k127_6065324_1 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000001898 203.0
EH2_k127_607050_0 MgtC family K07507 - - 0.00000000000000000000000000000000000003278 154.0
EH2_k127_607050_1 amine dehydrogenase activity - - - 0.000000000000003407 90.0
EH2_k127_607050_2 - - - - 0.00000000000001755 86.0
EH2_k127_6085386_0 Lamin Tail Domain - - - 0.000000000000000000000007213 117.0
EH2_k127_6091553_0 nucleotide metabolic process - - - 0.0000000000000000001205 100.0
EH2_k127_6094198_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 336.0
EH2_k127_6094198_1 Large extracellular alpha-helical protein K13735,K20276 - - 0.000000000000000006431 100.0
EH2_k127_6094198_2 S-layer protein - - - 0.0001707 49.0
EH2_k127_6104796_0 peptidase activity, acting on L-amino acid peptides K20276 - - 0.0000000001148 73.0
EH2_k127_6104796_1 self proteolysis - - - 0.000004496 55.0
EH2_k127_6112470_0 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000002714 139.0
EH2_k127_6112470_1 Domain of unknown function - - - 0.00000000000000000008557 106.0
EH2_k127_6113093_0 S-layer homology domain - - - 0.0000000000000000000000000000000000001099 165.0
EH2_k127_6113093_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000004598 89.0
EH2_k127_6113093_2 PFAM PKD domain containing protein - - - 0.00000000000009904 84.0
EH2_k127_6113093_3 Zc3h12a-like Ribonuclease NYN domain - - - 0.000000001604 70.0
EH2_k127_6113093_4 Acetyltransferase (GNAT) domain K03828 - - 0.00000008388 60.0
EH2_k127_6130768_0 methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000001283 179.0
EH2_k127_6130768_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000001578 83.0
EH2_k127_6130768_2 domain protein - - - 0.0000000000001212 85.0
EH2_k127_6146591_0 Glycosyl transferase - - - 0.0000000000000000000000000000004352 133.0
EH2_k127_6153311_0 - K06193 - - 0.0000002007 55.0
EH2_k127_6153311_1 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000005089 58.0
EH2_k127_6155535_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.726e-291 914.0
EH2_k127_6163780_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.00002151 57.0
EH2_k127_6165290_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 351.0
EH2_k127_6165290_1 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 323.0
EH2_k127_6165290_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003217 231.0
EH2_k127_6165290_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000005187 221.0
EH2_k127_6165290_4 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000000004213 214.0
EH2_k127_6165290_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000001507 171.0
EH2_k127_6165290_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000002067 160.0
EH2_k127_6165290_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000002666 131.0
EH2_k127_6165290_8 AIG2-like family - - - 0.0000000000000007768 86.0
EH2_k127_6165290_9 SMART Parallel beta-helix repeat - - - 0.00003934 57.0
EH2_k127_6173853_0 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.0000000000000000000000000000000000000000000000000000000002266 211.0
EH2_k127_6173853_1 FeoA K03709 - - 0.00000000000000000000000000005348 124.0
EH2_k127_6173853_2 belongs to the CobB CobQ family K00625,K13788 - 2.3.1.8 0.0000000000000002732 90.0
EH2_k127_6177253_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 592.0
EH2_k127_6177253_1 - - - - 0.0000000007652 67.0
EH2_k127_6177862_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 370.0
EH2_k127_6177862_1 involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.0000000000000000000000000000000000000005717 156.0
EH2_k127_6178596_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000001942 191.0
EH2_k127_6178596_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0008459 49.0
EH2_k127_6180045_0 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000008902 131.0
EH2_k127_6180045_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.00000000000000000007158 101.0
EH2_k127_6180045_2 4-vinyl reductase, 4VR - - - 0.0000008084 59.0
EH2_k127_618766_0 PUA domain containing protein K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 484.0
EH2_k127_618766_1 transcriptional - - - 0.000000008733 66.0
EH2_k127_6192260_0 Protein of unknown function, DUF255 K06888 - - 2.042e-252 797.0
EH2_k127_6192260_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 396.0
EH2_k127_6192260_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000001741 204.0
EH2_k127_6192260_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000002428 191.0
EH2_k127_6192260_4 SCO1/SenC - - - 0.000000000000000000000000000000000000000000000000000336 188.0
EH2_k127_6192260_5 protein conserved in archaea K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.000003005 57.0
EH2_k127_6193493_0 PFAM Flavodoxin K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 521.0
EH2_k127_6193493_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006349 234.0
EH2_k127_6193493_2 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000007722 120.0
EH2_k127_6193493_3 PFAM Rubredoxin - - - 0.000000000000000000000002632 102.0
EH2_k127_6197186_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.707e-310 981.0
EH2_k127_6197186_1 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 539.0
EH2_k127_6197186_10 protein tyrosine phosphatase activity K17341,K19636 - - 0.0000000000435 76.0
EH2_k127_6197186_11 Reeler domain - - - 0.0000001881 64.0
EH2_k127_6197186_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 462.0
EH2_k127_6197186_3 PFAM Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 409.0
EH2_k127_6197186_4 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002924 265.0
EH2_k127_6197186_5 Belongs to the archaeal-type DHQ synthase family K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000478 239.0
EH2_k127_6197186_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000001951 148.0
EH2_k127_6197186_7 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000004345 155.0
EH2_k127_6197186_8 - - - - 0.0000000000000000000000000000000000007118 146.0
EH2_k127_6197186_9 Alpha beta hydrolase - - - 0.000000000000000001299 98.0
EH2_k127_6214091_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 8.176e-198 639.0
EH2_k127_6214091_1 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000001089 232.0
EH2_k127_6214091_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 2.7.7.3 0.0000000000000000000000000002148 124.0
EH2_k127_6214091_3 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0000005318 54.0
EH2_k127_6221364_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 421.0
EH2_k127_6221364_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000002796 214.0
EH2_k127_6221364_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000003939 169.0
EH2_k127_6221364_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004427 153.0
EH2_k127_6221364_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003505 126.0
EH2_k127_6221364_5 RNA polymerases N / 8 kDa subunit K02912,K03007,K11313,K15271 GO:0000375,GO:0000377,GO:0000398,GO:0000418,GO:0000419,GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0005666,GO:0005730,GO:0005736,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006351,GO:0006352,GO:0006353,GO:0006354,GO:0006355,GO:0006356,GO:0006360,GO:0006361,GO:0006363,GO:0006366,GO:0006367,GO:0006368,GO:0006370,GO:0006383,GO:0006396,GO:0006397,GO:0006399,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0008150,GO:0008152,GO:0008270,GO:0008380,GO:0008543,GO:0009058,GO:0009059,GO:0009301,GO:0009304,GO:0009452,GO:0009719,GO:0009889,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0016070,GO:0016071,GO:0016073,GO:0016591,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0030880,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0033554,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0036260,GO:0040029,GO:0042221,GO:0042795,GO:0042797,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0045815,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0055029,GO:0060147,GO:0060255,GO:0060964,GO:0060966,GO:0060968,GO:0061695,GO:0065007,GO:0070013,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0080090,GO:0090304,GO:0097659,GO:0097747,GO:0098781,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 3.6.4.12 0.00000000000000000004171 93.0
EH2_k127_6221364_6 membrane-associated protein domain - - - 0.00000116 59.0
EH2_k127_6224110_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 476.0
EH2_k127_6224110_1 Methyltransferase - - - 0.000000000000000000001618 105.0
EH2_k127_6235637_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 438.0
EH2_k127_6235637_1 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 346.0
EH2_k127_6235637_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000001218 109.0
EH2_k127_6250696_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 500.0
EH2_k127_6250696_1 isochorismatase - - - 0.00000000000000000000000000000000000021 152.0
EH2_k127_6250696_2 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000000000000000001377 130.0
EH2_k127_6270841_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 444.0
EH2_k127_6270841_1 Isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000002559 278.0
EH2_k127_6270841_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000001767 196.0
EH2_k127_6273204_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 604.0
EH2_k127_6273204_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 303.0
EH2_k127_6311956_0 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 497.0
EH2_k127_6311956_1 Di-glucose binding within endoplasmic reticulum - - - 0.0001144 53.0
EH2_k127_6335283_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000136 243.0
EH2_k127_6335283_1 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000006534 60.0
EH2_k127_6340921_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 470.0
EH2_k127_6340921_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000002304 261.0
EH2_k127_6340921_2 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000001223 196.0
EH2_k127_6341225_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 302.0
EH2_k127_6341225_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000031 188.0
EH2_k127_6341225_2 Sulfurtransferase TusA - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000001753 94.0
EH2_k127_6351181_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.417e-252 799.0
EH2_k127_6358967_0 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 370.0
EH2_k127_6358967_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001704 283.0
EH2_k127_6358967_2 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000005069 126.0
EH2_k127_6378921_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.726e-254 808.0
EH2_k127_6378921_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 514.0
EH2_k127_6378921_2 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004555 278.0
EH2_k127_6378921_3 DnaB-like helicase C terminal domain - - - 0.00000000000000000000000000000000000006802 151.0
EH2_k127_6378921_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000002986 85.0
EH2_k127_6380162_0 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 291.0
EH2_k127_6380162_1 DHH family - - - 0.000000000000000000000000000007322 131.0
EH2_k127_6380162_2 binds to the 23S rRNA K02921 - - 0.00000000000000005285 85.0
EH2_k127_6380162_3 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000001026 57.0
EH2_k127_6380162_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000123 64.0
EH2_k127_6380162_5 Transcription factor Pcc1 K09741 - - 0.0006157 48.0
EH2_k127_638322_0 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000006083 219.0
EH2_k127_638322_1 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000004313 172.0
EH2_k127_638322_2 Cupin domain - - - 0.000000000000000000000000000000000000003624 158.0
EH2_k127_638322_3 Maf-like protein K06287 - - 0.000000000000000000000000000001755 132.0
EH2_k127_638322_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000003311 79.0
EH2_k127_638367_0 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002173 252.0
EH2_k127_638367_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001095 247.0
EH2_k127_638367_2 Beta-propeller repeat - - - 0.000000000000000000000007071 112.0
EH2_k127_638367_3 KaiC - - - 0.000000000000000002131 94.0
EH2_k127_6414324_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 447.0
EH2_k127_6414324_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000005264 244.0
EH2_k127_6414324_2 endonuclease III K07457 - - 0.000000000000000001179 89.0
EH2_k127_6420014_0 PA14 - - - 0.00000000000000000000000000000003654 146.0
EH2_k127_6434874_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 362.0
EH2_k127_6434874_1 PFAM SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000007999 271.0
EH2_k127_6434874_2 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000004205 194.0
EH2_k127_6434874_3 - - - - 0.0000000000000000000000000006478 113.0
EH2_k127_6434874_4 Lrp/AsnC ligand binding domain - - - 0.00000000000000000001014 95.0
EH2_k127_6434874_5 - - - - 0.00000000000172 68.0
EH2_k127_6459762_0 NmrA-like family - - - 0.000000000000000000000000000001484 138.0
EH2_k127_6459762_1 PFAM Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000001144 132.0
EH2_k127_6462464_0 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008723 300.0
EH2_k127_6462464_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000002619 149.0
EH2_k127_6462464_2 Cadherin repeats. - - - 0.00000000000000000000000000000000005217 154.0
EH2_k127_6462464_3 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000003338 135.0
EH2_k127_6462464_4 Cysteine-rich domain - - - 0.00000000000000000001885 107.0
EH2_k127_6464201_0 Belongs to the ompA family - - - 0.000000000000000000002422 111.0
EH2_k127_6464201_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000006431 99.0
EH2_k127_6464201_2 domain, Protein - - - 0.00000000000001622 89.0
EH2_k127_6464201_3 Glycosyl hydrolase family 12 K01179,K01218,K20276 - 3.2.1.4,3.2.1.78 0.00000005132 61.0
EH2_k127_648952_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.283e-204 651.0
EH2_k127_648952_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000001801 123.0
EH2_k127_6498030_0 Transglutaminase-like - - - 0.0000000000000001239 95.0
EH2_k127_6530926_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 326.0
EH2_k127_6530926_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 310.0
EH2_k127_6530926_2 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005496 274.0
EH2_k127_6530926_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000001984 220.0
EH2_k127_6530926_4 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000198 137.0
EH2_k127_6530926_5 Fcf1 K07158 - - 0.00000000000001523 85.0
EH2_k127_6540177_0 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 294.0
EH2_k127_6540177_1 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000755 245.0
EH2_k127_6540177_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000006671 239.0
EH2_k127_6540177_3 Predicted membrane protein (DUF2070) K08979 - - 0.000000000000000000000000000000000000000000000000000000002232 227.0
EH2_k127_6540177_4 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000003018 181.0
EH2_k127_6540547_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000002649 240.0
EH2_k127_6540547_1 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000006717 155.0
EH2_k127_6540547_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000001887 89.0
EH2_k127_6540547_3 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000001584 83.0
EH2_k127_6561613_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000001516 139.0
EH2_k127_6561613_1 Diguanylate cyclase - - - 0.00000002714 66.0
EH2_k127_6565240_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000002733 152.0
EH2_k127_6565240_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000003843 77.0
EH2_k127_6565240_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00001142 56.0
EH2_k127_6586052_0 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 319.0
EH2_k127_6586052_1 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 293.0
EH2_k127_6587858_0 AAA domain - - - 0.00000000000000000000000000000000002379 145.0
EH2_k127_6617959_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 385.0
EH2_k127_6651641_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 266.0
EH2_k127_6651641_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000001752 232.0
EH2_k127_6651641_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000002821 222.0
EH2_k127_6651641_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000003914 79.0
EH2_k127_6651641_4 ABC transporter (Permease) K02004 - - 0.000000004046 69.0
EH2_k127_6657373_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 391.0
EH2_k127_6661211_0 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000101 259.0
EH2_k127_6661211_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000308 235.0
EH2_k127_6661211_2 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000004559 120.0
EH2_k127_667424_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 539.0
EH2_k127_667424_1 PRC-barrel domain - - - 0.000000000000000000000000001611 113.0
EH2_k127_667424_2 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000007629 81.0
EH2_k127_667424_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000005771 69.0
EH2_k127_667424_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000001875 61.0
EH2_k127_667424_5 COG0438 Glycosyltransferase - - - 0.00005865 56.0
EH2_k127_6678155_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000002765 242.0
EH2_k127_6714412_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 3.294e-203 642.0
EH2_k127_6714412_1 PFAM ribosomal protein S8E K02995 - - 0.0000000000000000000000126 102.0
EH2_k127_6714412_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000006131 79.0
EH2_k127_6714412_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00006045 46.0
EH2_k127_6723078_0 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000008593 152.0
EH2_k127_6723078_1 - - - - 0.000000000000000000000000000002422 133.0
EH2_k127_6723078_2 - - - - 0.0000000000145 69.0
EH2_k127_6723078_3 - - - - 0.00000001992 66.0
EH2_k127_6723078_4 Glycosyl transferase, family 2 - - - 0.0000001596 65.0
EH2_k127_6723078_5 integral membrane protein - - - 0.000005192 58.0
EH2_k127_6723078_6 - - - - 0.0009509 51.0
EH2_k127_6739208_0 Pyruvate kinase, barrel domain K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 351.0
EH2_k127_6739208_1 REJ domain K06572 - - 0.00006016 52.0
EH2_k127_6741692_0 Creatinine amidohydrolase K01470 - 3.5.2.10 3.564e-293 927.0
EH2_k127_6741692_1 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 494.0
EH2_k127_6741692_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 462.0
EH2_k127_6741692_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 429.0
EH2_k127_6741692_4 PFAM PKD domain containing protein - - - 0.000000000000000000000524 105.0
EH2_k127_6746566_0 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002727 260.0
EH2_k127_6746566_1 - - - - 0.000000000002505 74.0
EH2_k127_6746737_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 623.0
EH2_k127_6746737_1 Belongs to the ompA family - - - 0.00000000001467 78.0
EH2_k127_6746737_2 oxidoreductase activity - - - 0.00000000007143 76.0
EH2_k127_6750557_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
EH2_k127_6750557_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000167 192.0
EH2_k127_6750557_2 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000415 144.0
EH2_k127_6750557_3 addiction module toxin, RelE StbE family - - - 0.000000000000000000000007006 103.0
EH2_k127_6750557_4 Protein of unknown function (DUF2683) - - - 0.0000002181 55.0
EH2_k127_6774549_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000001698 246.0
EH2_k127_6774549_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000002698 162.0
EH2_k127_6774549_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000001205 128.0
EH2_k127_6774549_3 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000001267 126.0
EH2_k127_6774549_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.00000000000001025 81.0
EH2_k127_6774549_5 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000001518 56.0
EH2_k127_6785815_0 CBS domain K03699 - - 0.000000000000000000000000000000000000008365 158.0
EH2_k127_6785815_1 Xylose isomerase domain protein TIM barrel - - - 0.000000000001387 78.0
EH2_k127_6786142_0 Belongs to the ompA family K20276 - - 0.000000000008062 80.0
EH2_k127_6786142_1 Transglutaminase-like protein - - - 0.0000003686 64.0
EH2_k127_6790807_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 544.0
EH2_k127_6798614_0 SMART ATPase, AAA type, core K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 327.0
EH2_k127_6798614_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000001584 166.0
EH2_k127_6798614_2 ABC-2 family transporter protein K01992 - - 0.0000000002494 74.0
EH2_k127_6801777_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 461.0
EH2_k127_6801777_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000001412 104.0
EH2_k127_6815874_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 417.0
EH2_k127_6815874_1 membrane transporter protein K07090 - - 0.000000000001839 74.0
EH2_k127_682642_0 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000000004562 161.0
EH2_k127_682642_1 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000008144 71.0
EH2_k127_6849689_0 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
EH2_k127_6849689_1 SMART Parallel beta-helix repeat - - - 0.00000000000000000000005633 115.0
EH2_k127_6849970_0 Peptidase S8 K08651 - 3.4.21.66 0.00000000000000002935 97.0
EH2_k127_6853501_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 427.0
EH2_k127_6853501_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 373.0
EH2_k127_6853501_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
EH2_k127_6853501_3 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
EH2_k127_6853501_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000005699 207.0
EH2_k127_6853501_5 oxidoreductase subunit delta K00171 - 1.2.7.1 0.00000000000000000000000001139 113.0
EH2_k127_6853501_6 Transcriptional regulator - - - 0.0000000000000000000148 107.0
EH2_k127_6872100_0 Heat shock 70 kDa protein K04043 - - 2.788e-244 771.0
EH2_k127_6872100_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000002035 125.0
EH2_k127_6872100_2 Membrane protein of unknown function DUF63 - - - 0.00000000000000002964 89.0
EH2_k127_6872100_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000002751 75.0
EH2_k127_6873884_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000002827 201.0
EH2_k127_6873884_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000004472 89.0
EH2_k127_6873884_2 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000652 72.0
EH2_k127_6910528_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000005367 248.0
EH2_k127_6911063_0 Flavodoxin K03809 - 1.6.5.2 0.000000000002538 68.0
EH2_k127_6911063_1 RHS Repeat - - - 0.00000005279 66.0
EH2_k127_691345_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 353.0
EH2_k127_6919619_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000001763 118.0
EH2_k127_6919619_1 NHL repeat - - - 0.0002632 55.0
EH2_k127_6922106_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 557.0
EH2_k127_6922106_1 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000003515 203.0
EH2_k127_6945136_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 530.0
EH2_k127_6945136_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000004427 228.0
EH2_k127_6949076_0 PFAM ABC transporter related K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 364.0
EH2_k127_6949076_1 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 294.0
EH2_k127_6949076_10 helix_turn_helix ASNC type - - - 0.0003244 48.0
EH2_k127_6949076_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004187 272.0
EH2_k127_6949076_3 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000002593 244.0
EH2_k127_6949076_4 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000001193 136.0
EH2_k127_6949076_5 peptidase activity, acting on L-amino acid peptides K01448,K07260,K09955,K13276 GO:0005575,GO:0005576 3.4.17.14,3.5.1.28 0.0000000000000007407 94.0
EH2_k127_6949076_6 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.0000000000001949 71.0
EH2_k127_6949076_7 RNA-binding - - - 0.0000000001006 62.0
EH2_k127_6949076_9 Domain of unknown function (DUF4082) - - - 0.0000301 59.0
EH2_k127_7005659_0 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000005291 128.0
EH2_k127_700634_0 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009643 330.0
EH2_k127_700634_1 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000006986 239.0
EH2_k127_700634_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000004182 198.0
EH2_k127_700634_3 protein conserved in archaea - - - 0.00000000000000000005459 95.0
EH2_k127_7015018_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000001454 91.0
EH2_k127_7023908_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 394.0
EH2_k127_7023908_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
EH2_k127_7023908_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 322.0
EH2_k127_7023908_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000001561 140.0
EH2_k127_7035746_0 PKD domain - - - 0.00008668 55.0
EH2_k127_7079505_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004159 304.0
EH2_k127_7079505_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000121 139.0
EH2_k127_708393_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 457.0
EH2_k127_708393_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 416.0
EH2_k127_708393_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003892 293.0
EH2_k127_708393_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000001269 222.0
EH2_k127_708393_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000001604 144.0
EH2_k127_708393_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000002374 147.0
EH2_k127_708393_6 snRNP Sm proteins K04796 - - 0.000000000000000002729 90.0
EH2_k127_708404_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000002922 189.0
EH2_k127_708404_1 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000001632 105.0
EH2_k127_708404_2 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000006324 86.0
EH2_k127_708404_3 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000001533 62.0
EH2_k127_7092581_0 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005927 280.0
EH2_k127_7092581_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000001688 239.0
EH2_k127_7092581_2 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000008811 122.0
EH2_k127_7092581_3 Small multi-drug export protein - - - 0.00000000000000000001933 101.0
EH2_k127_7092581_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000001785 82.0
EH2_k127_7092581_5 OmpA family - - - 0.0000007624 60.0
EH2_k127_7094658_0 methyltransferase - - - 0.000000003631 67.0
EH2_k127_7096588_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 430.0
EH2_k127_7096588_1 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000002735 172.0
EH2_k127_7096588_2 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.000000000000000000000000000001 136.0
EH2_k127_7121191_0 DNA polymerase type-B family K02319 - 2.7.7.7 5.296e-259 823.0
EH2_k127_7121191_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 473.0
EH2_k127_7121191_2 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002863 290.0
EH2_k127_7121191_3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003065 266.0
EH2_k127_7121191_4 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001298 267.0
EH2_k127_7121191_5 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000004074 252.0
EH2_k127_7122364_0 heat shock protein binding - - - 0.00000003335 64.0
EH2_k127_7131994_0 Transglutaminase-like domain - - - 0.0000000000000000000000000000000297 144.0
EH2_k127_7131994_1 Protein of unknown function DUF58 - - - 0.0000000000007236 81.0
EH2_k127_7131994_2 Domain of unknown function (DUF4129) - - - 0.00002008 57.0
EH2_k127_7158337_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000007227 238.0
EH2_k127_7158337_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000004458 146.0
EH2_k127_7158337_2 oxidase subunit III K02299 - - 0.000000000000000000000000000000001427 140.0
EH2_k127_7158337_3 cytochrome C oxidase subunit K02275 - 1.9.3.1 0.00000000000000000000000000001006 135.0
EH2_k127_71728_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000002373 186.0
EH2_k127_71728_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000004781 90.0
EH2_k127_71728_2 chitin binding K01081,K01183,K20276 - 3.1.3.5,3.2.1.14 0.0000000000007668 81.0
EH2_k127_71728_3 OPT oligopeptide transporter protein - - - 0.00000000003763 76.0
EH2_k127_7178205_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 613.0
EH2_k127_7178205_1 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000000003501 243.0
EH2_k127_7178205_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000004254 198.0
EH2_k127_7178205_3 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000001411 133.0
EH2_k127_7178205_4 PFAM Ribosomal LX protein K02944 - - 0.0000001172 58.0
EH2_k127_7178205_5 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.0000005352 53.0
EH2_k127_7202857_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 428.0
EH2_k127_7202857_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001448 288.0
EH2_k127_7202857_2 Protein of unknown function TPD sequence-motif - - - 0.0000000000000000000000000000000000000005928 168.0
EH2_k127_7208406_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002038 245.0
EH2_k127_7208406_1 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000001175 209.0
EH2_k127_7208406_2 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000009281 91.0
EH2_k127_7212646_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 402.0
EH2_k127_7212646_1 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000001274 122.0
EH2_k127_7216220_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
EH2_k127_7216220_1 DNA binding protein K06930 - - 0.00000000000000000000001239 111.0
EH2_k127_72384_0 amine dehydrogenase activity - - - 0.0000000000000000000000004066 124.0
EH2_k127_7241531_0 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000003009 107.0
EH2_k127_7247428_0 transcription regulator activity - - - 0.0000000000000000008096 94.0
EH2_k127_7247428_1 transcription regulator activity - - - 0.000000000000000003072 93.0
EH2_k127_7247428_2 transcription regulator activity K03718 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000001479 78.0
EH2_k127_7264453_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 413.0
EH2_k127_7264453_1 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 396.0
EH2_k127_7264453_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000001129 70.0
EH2_k127_7270096_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000003757 211.0
EH2_k127_7270096_1 - - - - 0.00000000000001354 82.0
EH2_k127_7270096_2 Predicted membrane protein (DUF2318) - - - 0.000001426 51.0
EH2_k127_7283174_0 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity K05592 GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 352.0
EH2_k127_7321547_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.000000000000000000000000000000008874 136.0
EH2_k127_7321547_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000156 88.0
EH2_k127_7322061_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000004068 168.0
EH2_k127_7327773_0 PKD domain - - - 0.0000000138 69.0
EH2_k127_7349502_0 myosin light chain kinase activity K12567 - 2.7.11.1 0.000000000000000000000000000000029 145.0
EH2_k127_7349502_1 Beta-propeller repeat - - - 0.00000004033 66.0
EH2_k127_7390981_0 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000002184 128.0
EH2_k127_7390981_1 Fibronectin type III domain protein - - - 0.0000000000000000000000001142 121.0
EH2_k127_7390981_2 Periplasmic or secreted lipoprotein - - - 0.0007824 51.0
EH2_k127_74153_0 glycoside hydrolase, family - - - 0.000000000000000000000000000000000000000000151 178.0
EH2_k127_7416739_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 324.0
EH2_k127_7470039_0 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000000000011 102.0
EH2_k127_7470039_1 metallopeptidase activity - - - 0.0000000000000387 87.0
EH2_k127_7470039_2 PFAM PKD domain containing protein - - - 0.00000000009336 72.0
EH2_k127_7470039_3 Pfam:DUF552 K09152 - - 0.00002287 46.0
EH2_k127_7470100_0 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000001835 219.0
EH2_k127_7470198_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002 307.0
EH2_k127_7499780_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000001759 179.0
EH2_k127_7499780_1 MoaE protein K21142 - 2.8.1.12 0.00000000000022 79.0
EH2_k127_7499780_2 domain protein - - - 0.0000000001332 76.0
EH2_k127_7499780_3 SCP-2 sterol transfer family - - - 0.0000000004703 70.0
EH2_k127_7499780_4 Protein of unknown function (DUF2721) - - - 0.00000009628 60.0
EH2_k127_7499780_5 Regulator of chromosome condensation (RCC1) repeat - - - 0.0007674 51.0
EH2_k127_7502948_0 Helix-turn-helix XRE-family like proteins K07728 - - 0.0000000000000000000000000000000000000000000000000000007586 205.0
EH2_k127_7502948_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000002939 88.0
EH2_k127_7502948_2 - - - - 0.0000000009415 69.0
EH2_k127_7514525_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000001108 158.0
EH2_k127_7514525_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000009342 137.0
EH2_k127_7514525_2 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000001801 123.0
EH2_k127_7538636_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 455.0
EH2_k127_7538636_1 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000009906 143.0
EH2_k127_7538636_2 4Fe-4S dicluster domain - - - 0.00000000000000000000003533 105.0
EH2_k127_7543096_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 378.0
EH2_k127_7543096_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.0000000000000000000000000000000000000000001442 179.0
EH2_k127_7543096_2 myosin light chain kinase activity K12567 - 2.7.11.1 0.00000000000000000000000000000000000008269 166.0
EH2_k127_7543096_4 transporter - - - 0.0001049 53.0
EH2_k127_756672_0 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004385 273.0
EH2_k127_756672_1 alpha/beta hydrolase fold - - - 0.00000511 51.0
EH2_k127_756672_2 Domain of unknown function (DUF4347) - - - 0.0002536 54.0
EH2_k127_756672_3 VanZ like family - - - 0.0004608 48.0
EH2_k127_7588197_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000005246 139.0
EH2_k127_7589430_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1183.0
EH2_k127_7589430_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009826 253.0
EH2_k127_7589430_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000003857 192.0
EH2_k127_7598160_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 334.0
EH2_k127_7598160_1 archaeal Zn-finger protein - - - 0.000000000000002895 83.0
EH2_k127_7598160_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000003352 84.0
EH2_k127_7598160_3 - - - - 0.000003258 58.0
EH2_k127_7598160_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000663 50.0
EH2_k127_7598160_5 Universal stress protein A-like protein - GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0002651 49.0
EH2_k127_7599261_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0000000000000000000000000000000003332 144.0
EH2_k127_7599261_1 Dystroglycan-type cadherin-like domains. - - - 0.0000005502 62.0
EH2_k127_7604126_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000885 201.0
EH2_k127_763033_0 Acetyltransferase (GNAT) domain K03817 - - 0.0000000000000000000000000000000000000000000000000009901 188.0
EH2_k127_763033_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000002515 133.0
EH2_k127_763033_2 Peptidase family C25 - - - 0.000000000000000000000000000000285 144.0
EH2_k127_763033_3 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000005186 121.0
EH2_k127_763033_4 PFAM DsrE K07235 - - 0.0000000000000001189 89.0
EH2_k127_763033_5 domain protein K01179,K01342,K01406,K07004,K12287,K14194,K15125,K20276 - 3.2.1.4,3.4.21.62,3.4.24.40 0.0000000000003445 84.0
EH2_k127_763033_6 Belongs to the DsrF TusC family K07236 - - 0.000000000004207 72.0
EH2_k127_763033_7 DsrH like protein K07237 - - 0.00000003119 59.0
EH2_k127_7637488_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 337.0
EH2_k127_7637488_1 PKD domain - - - 0.000000002455 70.0
EH2_k127_7662284_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000001083 229.0
EH2_k127_7662284_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.7.7.2 0.0000000000000000000000000000000001092 154.0
EH2_k127_7662284_2 - - - - 0.000000000001452 76.0
EH2_k127_7662284_3 Thiamine-binding protein - - - 0.000000001448 60.0
EH2_k127_7662284_4 Reeler domain - - - 0.00000001684 66.0
EH2_k127_7677015_0 PEP-utilising enzyme, mobile domain K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 580.0
EH2_k127_7677015_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 495.0
EH2_k127_7677015_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005744 268.0
EH2_k127_7677015_3 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000002379 201.0
EH2_k127_7681976_0 to SP P29212 GB L02649 GB X70994 PID 581070 GB U00096 percent identity K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 492.0
EH2_k127_7681976_1 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000000006643 74.0
EH2_k127_7737637_0 cytochrome c biogenesis protein K06196 - - 0.0000000000000000005925 98.0
EH2_k127_7738484_0 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 377.0
EH2_k127_7738484_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 315.0
EH2_k127_7738484_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000147 94.0
EH2_k127_7738484_3 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000006961 72.0
EH2_k127_7738484_4 Phospholipase_D-nuclease N-terminal - - - 0.00000000001076 70.0
EH2_k127_7738484_5 Phospholipase_D-nuclease N-terminal - - - 0.00000000002453 68.0
EH2_k127_7738484_6 Phospholipase_D-nuclease N-terminal - - - 0.00000000005917 69.0
EH2_k127_7738484_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000004285 69.0
EH2_k127_7740824_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000001392 116.0
EH2_k127_7740824_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000004935 68.0
EH2_k127_7748208_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 351.0
EH2_k127_7748208_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0005 48.0
EH2_k127_7752573_0 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000004098 110.0
EH2_k127_7752573_1 glucose sorbosone - - - 0.00000003256 67.0
EH2_k127_7764654_0 Helix-turn-helix domain K07731 - - 0.00000000000000000000000000000000000001038 149.0
EH2_k127_7764654_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000001406 73.0
EH2_k127_7764654_2 deoxyhypusine monooxygenase activity K01387 - 3.4.24.3 0.0000000001727 74.0
EH2_k127_7767060_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 412.0
EH2_k127_7767060_1 - - - - 0.00007521 51.0
EH2_k127_77752_0 - - - - 0.00000000000000000000000001244 119.0
EH2_k127_77752_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000003419 66.0
EH2_k127_7775250_0 S-layer like family, C-terminal region - - - 0.00000002048 67.0
EH2_k127_7782568_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006858 261.0
EH2_k127_7796547_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0007183 52.0
EH2_k127_7799472_0 Oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000003575 212.0
EH2_k127_7799472_1 glutaconyl-CoA decarboxylase subunit gamma K01615 - 4.1.1.70 0.00000000000000321 83.0
EH2_k127_7799472_2 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000359 49.0
EH2_k127_7831499_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000002531 153.0
EH2_k127_7831747_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 372.0
EH2_k127_7831747_1 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000883 173.0
EH2_k127_7831747_2 Glycine cleavage system H protein K02437 - - 0.0000000000000000000000000000000000001197 145.0
EH2_k127_7831747_3 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000009151 138.0
EH2_k127_7831747_4 NUDIX domain - - - 0.0000000000000000000000000001939 123.0
EH2_k127_7861613_0 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000002147 214.0
EH2_k127_7861613_1 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000006711 137.0
EH2_k127_7861613_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000002026 123.0
EH2_k127_7861613_3 TPR Domain containing protein - - - 0.0000000000000000001662 98.0
EH2_k127_7866083_0 Thioredoxin domain K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
EH2_k127_7866083_1 PFAM FecR protein - - - 0.0000006283 63.0
EH2_k127_7867413_0 myosin light chain kinase activity K12567 - 2.7.11.1 0.000000000000000000000000000005271 136.0
EH2_k127_7877797_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
EH2_k127_7877797_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000006162 159.0
EH2_k127_7877797_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000009364 113.0
EH2_k127_7877797_3 PRC-barrel domain - - - 0.0000000000000000000473 94.0
EH2_k127_7877797_4 UbiA prenyltransferase family - - - 0.000000002707 69.0
EH2_k127_7883182_0 regulation of response to stimulus K01347,K20276 - 3.4.21.72 0.0000000000000000004289 101.0
EH2_k127_7883182_1 metallopeptidase activity - - - 0.0000000000008659 75.0
EH2_k127_7888986_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 348.0
EH2_k127_7913135_0 S-layer homology domain - - - 0.000000000000000000000000000000000000000000001269 183.0
EH2_k127_7926332_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 480.0
EH2_k127_7926332_1 electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 438.0
EH2_k127_7926332_2 electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 327.0
EH2_k127_7926332_3 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000008845 106.0
EH2_k127_7926564_0 CAAX protease self-immunity - - - 0.000000000000000000000002382 117.0
EH2_k127_7926564_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000003782 87.0
EH2_k127_7927610_0 PA14 domain - - - 0.000000000000000000001313 110.0
EH2_k127_7927610_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000216 58.0
EH2_k127_7929052_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.699e-203 649.0
EH2_k127_7929052_1 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004961 261.0
EH2_k127_7929052_2 Rubrerythrin - - - 0.000000000000000000000000000000000000001505 154.0
EH2_k127_7929052_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000005638 134.0
EH2_k127_7929052_4 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.0000000000000000000001958 98.0
EH2_k127_7929052_5 iron ion binding - - - 0.000000000000001519 77.0
EH2_k127_7930966_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 294.0
EH2_k127_7954084_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 386.0
EH2_k127_7954084_1 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000000000000000005821 104.0
EH2_k127_7954084_2 - - - - 0.0000000005384 63.0
EH2_k127_7962049_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000001231 159.0
EH2_k127_7962049_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000004765 124.0
EH2_k127_7963123_0 PFAM Type II secretion system protein E K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 593.0
EH2_k127_7963123_1 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 323.0
EH2_k127_7963123_2 KaiC K07331 - - 0.0000000000000000000000000000000000000000000000000000000000002728 219.0
EH2_k127_7963123_3 Flagella accessory protein C (FlaC) K07327,K07328 - - 0.0000000000000000001165 102.0
EH2_k127_7963123_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 - - 0.00000000000000009385 89.0
EH2_k127_7963123_5 Archaebacterial flagellin K07330 - - 0.000000000001412 74.0
EH2_k127_7963123_6 Archaeal flagellar protein F K07329 - - 0.000001115 56.0
EH2_k127_7967508_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000005147 203.0
EH2_k127_7967508_1 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000009213 154.0
EH2_k127_7967508_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136,K06167 - 3.1.4.55 0.0000000000000000000000000000005781 136.0
EH2_k127_7967508_3 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000001626 99.0
EH2_k127_7967508_4 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000004306 91.0
EH2_k127_7967508_5 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.000000000000945 70.0
EH2_k127_7991853_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000115 279.0
EH2_k127_7991853_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000002934 173.0
EH2_k127_7991853_2 CARDB - - - 0.00008644 55.0
EH2_k127_8012213_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000001781 143.0
EH2_k127_8016090_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000006676 159.0
EH2_k127_8016090_1 - - - - 0.0000000000000000000000006944 106.0
EH2_k127_8023018_0 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008507 289.0
EH2_k127_8035637_0 Domain of unknown function - - - 0.00000000000000000000000000003542 136.0
EH2_k127_808923_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 355.0
EH2_k127_808923_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000005801 178.0
EH2_k127_808923_2 RHS Repeat - - - 0.000000000000000000000002695 118.0
EH2_k127_809487_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000004703 153.0
EH2_k127_809487_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000158 138.0
EH2_k127_809487_2 Transport permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000003122 98.0
EH2_k127_8096238_0 Aldo/keto reductase family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000786 260.0
EH2_k127_8096238_1 PFAM Aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000706 256.0
EH2_k127_8096238_2 DNA methylase - - - 0.00000000001074 64.0
EH2_k127_8096307_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000009213 138.0
EH2_k127_8096307_1 Polysaccharide biosynthesis protein - - - 0.00000000007076 74.0
EH2_k127_8107249_0 metal-dependent membrane protease K07052 - - 0.000005255 59.0
EH2_k127_8109922_0 LemA family K03744 - - 0.000000000000000000000000000000000000004139 153.0
EH2_k127_8109922_1 TPM domain K06872 - - 0.000000000000000000000003413 111.0
EH2_k127_8109922_2 YoaP-like - - - 0.000001348 59.0
EH2_k127_8113392_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 318.0
EH2_k127_8113392_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000009103 117.0
EH2_k127_8113392_2 PFAM Thioredoxin K03671 - - 0.00000000000000000000000002798 117.0
EH2_k127_8121530_0 Hep Hag repeat protein - - - 0.000000001447 71.0
EH2_k127_8121530_1 Transcriptional regulator, ArsR family - - - 0.000001464 51.0
EH2_k127_812524_0 TonB-dependent receptor plug K02014 - - 0.0003111 52.0
EH2_k127_8138698_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000002893 241.0
EH2_k127_8138698_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000003119 59.0
EH2_k127_8156231_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 322.0
EH2_k127_8156231_2 PFAM PKD domain containing protein - - - 0.00000000000000000000000000542 131.0
EH2_k127_8156231_3 Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - 0.00000000000000000000000002088 115.0
EH2_k127_8156231_4 Nucleotidyltransferase domain - - - 0.000000000000385 76.0
EH2_k127_8156231_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0001854 49.0
EH2_k127_818384_0 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000004952 137.0
EH2_k127_8196087_0 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001401 246.0
EH2_k127_820950_0 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000003229 235.0
EH2_k127_820950_1 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000001988 229.0
EH2_k127_820950_2 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000001358 103.0
EH2_k127_820950_3 DEAD_2 K10844 - 3.6.4.12 0.00000000000000007728 96.0
EH2_k127_8219379_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005466 261.0
EH2_k127_8219379_1 Transcriptional regulator, ArsR family - - - 0.00000000000007487 84.0
EH2_k127_864586_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 395.0
EH2_k127_864586_1 acetyltransferase - - - 0.0000000000000000000000000000000000006271 143.0
EH2_k127_889399_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000002115 162.0
EH2_k127_889399_1 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000003009 118.0
EH2_k127_890907_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 379.0
EH2_k127_890907_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 357.0
EH2_k127_890907_2 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000006792 171.0
EH2_k127_890907_3 PFAM Transketolase central region K00615 - 2.2.1.1 0.00000000000000000000000000000000002381 150.0
EH2_k127_890907_4 Helix-turn-helix domain - - - 0.0000000000001241 75.0
EH2_k127_890907_5 Bacterial Ig-like domain (group 3) K20276 - - 0.0000000002707 74.0
EH2_k127_911326_0 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000000007358 157.0
EH2_k127_911326_1 transcription activator, effector binding - - - 0.00000000000000000000000000000000000000003134 157.0
EH2_k127_911326_2 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000001872 123.0
EH2_k127_911326_3 protein conserved in archaea K09746 - - 0.00002939 48.0
EH2_k127_944103_0 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000002603 205.0
EH2_k127_944103_1 Membrane - - - 0.00000000000000000000000000000000000008593 152.0
EH2_k127_949329_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000001563 83.0
EH2_k127_999927_0 Domain of unknown function - - - 0.0000004716 64.0
EH2_k127_999927_1 Fibronectin type III domain protein - - - 0.00000742 60.0