Overview

ID MAG01053
Name EH2_bin.37
Sample SMP0029
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order Bathyarchaeales
Family Bathycorpusculaceae
Genus DATKKK01
Species
Assembly information
Completeness (%) 78.37
Contamination (%) 3.32
GC content (%) 53.0
N50 (bp) 5,397
Genome size (bp) 1,127,190

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1125

Gene name Description KEGG GOs EC E-value Score Sequence
EH2_k127_1003510_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 558.0
EH2_k127_1003510_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 341.0
EH2_k127_104235_0 Putative Phosphatase - - - 0.00000000000000000000000615 110.0
EH2_k127_104235_1 helix_turn_helix ASNC type - - - 0.00000000000000000000003071 100.0
EH2_k127_104235_2 transcription regulator activity - - - 0.000000579 59.0
EH2_k127_104235_3 phosphate transport K07220 - - 0.00007475 49.0
EH2_k127_104235_4 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0001907 45.0
EH2_k127_1048635_0 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 615.0
EH2_k127_1048635_1 HELICc2 K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 437.0
EH2_k127_1048635_10 - - - - 0.000000000000000000008876 100.0
EH2_k127_1048635_11 - - - - 0.00003926 48.0
EH2_k127_1048635_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 377.0
EH2_k127_1048635_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 371.0
EH2_k127_1048635_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 354.0
EH2_k127_1048635_5 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit K07151 GO:0003674,GO:0003824,GO:0004576,GO:0004579,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0031984,GO:0032991,GO:0034645,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043687,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0098796,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000001532 245.0
EH2_k127_1048635_6 PFAM Molybdopterin guanine dinucleotide synthesis protein B K06947 - - 0.00000000000000000000000000000000000000000000000000587 197.0
EH2_k127_1048635_7 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000305 149.0
EH2_k127_1048635_8 PFAM CBS domain containing protein - - - 0.000000000000000000000001403 109.0
EH2_k127_1048635_9 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000001478 111.0
EH2_k127_112843_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 376.0
EH2_k127_112843_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 366.0
EH2_k127_112843_2 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000001797 180.0
EH2_k127_1158769_0 DEAD DEAH box helicase domain protein K03724 - - 5.777e-254 814.0
EH2_k127_1158769_1 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000003941 259.0
EH2_k127_1158769_2 - - - - 0.000392 44.0
EH2_k127_1163421_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000002807 237.0
EH2_k127_1163421_1 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000006269 205.0
EH2_k127_1163421_2 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000000000000002017 191.0
EH2_k127_1163421_3 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000004329 144.0
EH2_k127_1163421_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000005552 115.0
EH2_k127_1163421_5 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.0000000000005406 72.0
EH2_k127_1217292_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 462.0
EH2_k127_1217292_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000001717 231.0
EH2_k127_1217292_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000004115 202.0
EH2_k127_1217292_3 PFAM Pyruvate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000006018 200.0
EH2_k127_1233790_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 353.0
EH2_k127_1233790_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000007648 214.0
EH2_k127_1305804_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 390.0
EH2_k127_1305804_1 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000004535 184.0
EH2_k127_1325999_0 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000001623 239.0
EH2_k127_1325999_1 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000002167 145.0
EH2_k127_1325999_2 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00002879 53.0
EH2_k127_1398460_0 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001102 194.0
EH2_k127_1398460_1 PFAM CBS domain containing protein - - - 0.000000000000000000009287 98.0
EH2_k127_1398460_2 Flavodoxin - - - 0.0000000005866 63.0
EH2_k127_1398460_3 Flavodoxin - - - 0.000000294 55.0
EH2_k127_1398460_4 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00005401 46.0
EH2_k127_1405104_0 COG0433 Predicted ATPase K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
EH2_k127_1405104_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000002096 234.0
EH2_k127_1405104_2 Efflux ABC transporter permease protein K02004 - - 0.000000000000000000000000000000000000000006596 170.0
EH2_k127_1415117_0 Asparaginase K01424 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 453.0
EH2_k127_1415117_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 298.0
EH2_k127_1415117_2 GH3 auxin-responsive promoter - - - 0.00000000000005884 83.0
EH2_k127_1415117_3 deoxyhypusine monooxygenase activity - - - 0.000002003 55.0
EH2_k127_142535_0 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0016787,GO:0019538,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 426.0
EH2_k127_142535_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 411.0
EH2_k127_142535_2 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003308 281.0
EH2_k127_142535_3 FR47-like protein - - - 0.000000000000000000000000000000000000000002313 160.0
EH2_k127_142535_4 4Fe-4S binding domain - - - 0.0000000000000000000000001729 117.0
EH2_k127_142535_5 PFAM SNARE associated Golgi protein - - - 0.000000000000001256 83.0
EH2_k127_142535_7 GDP-mannose mannosyl hydrolase activity K00974,K03574,K16149,K16150,K18445 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11,2.4.1.18,2.7.7.72,3.6.1.55,3.6.1.61 0.000001445 51.0
EH2_k127_1463456_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
EH2_k127_1463456_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000001561 168.0
EH2_k127_1463456_2 Belongs to the UPF0200 family - - - 0.0000000000000000000000000000000000000000003774 164.0
EH2_k127_1463456_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000008757 97.0
EH2_k127_1540067_0 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000187 199.0
EH2_k127_1540067_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000009921 191.0
EH2_k127_1540067_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001045 141.0
EH2_k127_1540067_3 DNA-directed RNA polymerase, alpha subunit 40 kD subunit K03047 - 2.7.7.6 0.000000000000000000000000000007997 121.0
EH2_k127_1564341_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 497.0
EH2_k127_1564341_2 Right handed beta helix region - - - 0.0000000000000000000000000000000000003876 156.0
EH2_k127_1594265_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 397.0
EH2_k127_1594265_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000002101 179.0
EH2_k127_1594265_2 threonyl-tRNA aminoacylation K01881 - 6.1.1.15 0.0000000000000000000000000000000000003779 141.0
EH2_k127_1663986_0 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 408.0
EH2_k127_1663986_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 387.0
EH2_k127_1663986_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000001211 154.0
EH2_k127_1663986_3 Transglutaminase-like superfamily - - - 0.000000000001389 77.0
EH2_k127_1816266_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 450.0
EH2_k127_1816266_1 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 363.0
EH2_k127_1816266_2 Starch synthase catalytic K16149 - 2.4.1.18 0.000000000000000000000001464 111.0
EH2_k127_1818823_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 445.0
EH2_k127_1818823_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 311.0
EH2_k127_1818823_2 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 270.0
EH2_k127_1818823_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000008771 175.0
EH2_k127_1818823_4 Metallopeptidase family M24 - - - 0.00000002354 62.0
EH2_k127_1818823_5 PFAM thiamineS protein K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00001213 51.0
EH2_k127_1826234_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 302.0
EH2_k127_1826234_1 Domain of unknown function (DUF4177) - - - 0.000946 44.0
EH2_k127_1857229_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 295.0
EH2_k127_1857229_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000002225 182.0
EH2_k127_1857229_2 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.00000000000000000000000000000000000007227 151.0
EH2_k127_1857229_3 Involved in regulation of DNA replication K10725 - - 0.00000000000000003702 84.0
EH2_k127_1857229_4 regulatory protein, arsR - - - 0.0000000001754 65.0
EH2_k127_1877109_0 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 393.0
EH2_k127_1877109_1 - - - - 0.00000000000000000000000000008624 121.0
EH2_k127_188407_0 Cell division protein 48, CDC48, domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 303.0
EH2_k127_188407_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 306.0
EH2_k127_188407_2 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000000000000000000000000000000000000004358 214.0
EH2_k127_188407_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000001258 144.0
EH2_k127_188407_4 metallocarboxypeptidase activity K05996 - 3.4.17.18 0.000000003494 63.0
EH2_k127_188407_5 DinB family - - - 0.00000003203 61.0
EH2_k127_188407_6 - - - - 0.00001032 50.0
EH2_k127_1896082_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 394.0
EH2_k127_1896082_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000748 273.0
EH2_k127_1896082_2 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000157 135.0
EH2_k127_1896082_3 Cytidylyltransferase-like K02201 - 2.7.7.3 0.00000000000000000000000000000199 126.0
EH2_k127_1896082_4 Protein of unknown function (DUF763) K09003 - - 0.000000000001151 68.0
EH2_k127_1932428_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 417.0
EH2_k127_1932428_1 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.00000000000000000000000000000000000000000000000000000003033 201.0
EH2_k127_1932428_2 aminotransferase class I and II - - - 0.0000000000000000000006064 108.0
EH2_k127_1932428_3 Major facilitator Superfamily - - - 0.0000000000000005757 86.0
EH2_k127_1932428_4 Belongs to the UPF0235 family K09131 - - 0.000001563 54.0
EH2_k127_201634_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000002195 231.0
EH2_k127_201634_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000002672 173.0
EH2_k127_201634_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000001708 168.0
EH2_k127_201634_3 CoA binding domain - - - 0.0000000000000000000000000000000000001736 150.0
EH2_k127_2033844_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.801e-308 972.0
EH2_k127_2033844_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 508.0
EH2_k127_2033844_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 485.0
EH2_k127_2033844_3 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000006867 263.0
EH2_k127_2033844_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000003727 79.0
EH2_k127_2056866_0 PFAM Amidohydrolase 3 K00200 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 556.0
EH2_k127_2056866_1 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000008736 263.0
EH2_k127_2056866_2 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000001379 192.0
EH2_k127_2143948_0 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000002398 154.0
EH2_k127_2143948_1 Transcriptional regulator - - - 0.0000000001507 66.0
EH2_k127_2143948_2 Calcineurin-like phosphoesterase K06953 - - 0.00001435 50.0
EH2_k127_2191835_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 395.0
EH2_k127_2191835_1 Uncharacterized protein conserved in archaea (DUF2099) - - - 0.000000000000000000000000000000000000001339 160.0
EH2_k127_2191835_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000006032 106.0
EH2_k127_2221104_0 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 419.0
EH2_k127_2221104_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 312.0
EH2_k127_2221104_2 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.000000000000000000002404 98.0
EH2_k127_2221104_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000001044 100.0
EH2_k127_2221104_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000003416 57.0
EH2_k127_2232382_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 8.602e-232 727.0
EH2_k127_2232382_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 319.0
EH2_k127_2232382_2 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000007137 219.0
EH2_k127_2232382_3 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.0000000000000000000000000000000000000005812 153.0
EH2_k127_2232382_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.00000000000000000000000001185 111.0
EH2_k127_2236667_0 Belongs to the catalase family K03781 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 343.0
EH2_k127_2236667_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009812 277.0
EH2_k127_2236667_2 membrane K09790 - - 0.00000000000000000000000000000007954 130.0
EH2_k127_2236667_3 TIGRFAM Phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.00000000000000000000917 106.0
EH2_k127_2236667_4 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000004331 86.0
EH2_k127_2236667_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000005036 78.0
EH2_k127_2236667_6 OsmC-like protein K07397 - - 0.0000000642 61.0
EH2_k127_2236667_7 Protein of unknown function (DUF3795) - - - 0.000842 46.0
EH2_k127_2293078_0 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 394.0
EH2_k127_2293078_1 Dehydrogenase K00111,K15736 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 253.0
EH2_k127_2293078_2 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000002226 173.0
EH2_k127_2343505_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 540.0
EH2_k127_2343505_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 374.0
EH2_k127_2343505_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 293.0
EH2_k127_2343505_3 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000001552 229.0
EH2_k127_2343505_4 electron transfer activity K03615 - - 0.000000000000000000000000000000000000001733 166.0
EH2_k127_2343505_5 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000003846 143.0
EH2_k127_2343505_6 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000001329 108.0
EH2_k127_2343505_7 protein conserved in archaea - - - 0.00000000000002378 83.0
EH2_k127_2345795_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 2.165e-282 899.0
EH2_k127_2345795_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000007628 181.0
EH2_k127_2388730_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 330.0
EH2_k127_2388730_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one- carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 325.0
EH2_k127_2388730_2 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 294.0
EH2_k127_2388730_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000001199 181.0
EH2_k127_2388730_4 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000009708 123.0
EH2_k127_2388730_5 - - - - 0.0000003042 58.0
EH2_k127_2407046_0 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 421.0
EH2_k127_2407046_1 PFAM Oxidoreductase K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000000000000000000004097 255.0
EH2_k127_2407046_2 Met-10+ like-protein K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000006154 229.0
EH2_k127_2407046_3 transferase hexapeptide repeat containing protein K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000005113 209.0
EH2_k127_2407046_4 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.000000000000000000000000000148 130.0
EH2_k127_2407046_5 Trm112p-like protein - - - 0.00000000000000000000000005581 110.0
EH2_k127_2423536_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 391.0
EH2_k127_2423536_1 Heat shock 70 kDa protein K04043 - - 0.00000008851 56.0
EH2_k127_2423536_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0004406 49.0
EH2_k127_2431190_0 molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000001284 213.0
EH2_k127_2431190_1 Conserved hypothetical ATP binding protein K06883 - - 0.000000000000000000000008768 104.0
EH2_k127_2431190_2 PFAM PEGA domain - - - 0.0000000000000000051 96.0
EH2_k127_2431190_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000105 82.0
EH2_k127_2431190_4 - - - - 0.00000002714 61.0
EH2_k127_2434674_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 398.0
EH2_k127_2434674_1 Helix-turn-helix domain K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000005382 231.0
EH2_k127_2434674_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000003425 211.0
EH2_k127_2434674_3 H ACA RNA-protein complex K07569 - - 0.0000000000005246 72.0
EH2_k127_2434674_4 EamA-like transporter family K08978 - - 0.0001742 47.0
EH2_k127_2434674_5 oligosaccharyl transferase STT3 subunit - - - 0.0004221 50.0
EH2_k127_244278_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 433.0
EH2_k127_244278_1 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 373.0
EH2_k127_244278_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002758 175.0
EH2_k127_244278_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000000508 104.0
EH2_k127_244278_4 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000001477 92.0
EH2_k127_2492085_0 Transposase IS116 IS110 IS902 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 608.0
EH2_k127_2492085_1 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.0000000000000000000000000000000005955 136.0
EH2_k127_2492085_2 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.0000000000000000000000000000001313 126.0
EH2_k127_2492085_3 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein K07485 - - 0.000000000000000001384 87.0
EH2_k127_2492085_4 - - - - 0.00000002186 59.0
EH2_k127_250066_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 505.0
EH2_k127_250066_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 461.0
EH2_k127_250066_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 436.0
EH2_k127_250066_3 Suf system fes assembly protein K04488,K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000102 181.0
EH2_k127_2516727_0 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16164 - 3.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000361 261.0
EH2_k127_2516727_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000001932 201.0
EH2_k127_2516727_2 Acetyltransferase (GNAT) domain - - - 0.0000000009504 64.0
EH2_k127_2516727_3 Acetyltransferase (GNAT) domain - - - 0.00000006238 55.0
EH2_k127_2516727_4 Membrane protein-like protein - - - 0.00002472 53.0
EH2_k127_2563546_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000001126 233.0
EH2_k127_2563546_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000000000000000000000000000000000000000002554 172.0
EH2_k127_2571393_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 7.305e-264 844.0
EH2_k127_2571393_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000003961 220.0
EH2_k127_2571393_2 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000002934 193.0
EH2_k127_2593052_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 461.0
EH2_k127_2593052_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 305.0
EH2_k127_2593052_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000001197 90.0
EH2_k127_2593052_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00009032 55.0
EH2_k127_2601657_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 334.0
EH2_k127_2601657_1 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000002628 177.0
EH2_k127_2601657_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000002357 91.0
EH2_k127_2601657_3 response regulator, receiver K07669 - - 0.000000000000009139 81.0
EH2_k127_2601657_4 Archaeal TRASH domain - - - 0.00000005086 61.0
EH2_k127_2601657_5 Transcriptional regulator - - - 0.0000006536 54.0
EH2_k127_2601657_6 Belongs to the 'phage' integrase family K03733,K04763 - - 0.0007856 46.0
EH2_k127_2606235_0 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 338.0
EH2_k127_2606235_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 310.0
EH2_k127_2606235_10 Acetyltransferase (GNAT) family - - - 0.000000000006074 68.0
EH2_k127_2606235_11 Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4 U6 di-snRNP, spliceosomal U4 U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4 U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity) K12625 GO:0000375,GO:0000377,GO:0000398,GO:0000932,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005688,GO:0005730,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0030490,GO:0030532,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0035770,GO:0036464,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045292,GO:0046483,GO:0046540,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097525,GO:0097526,GO:0120114,GO:0120115,GO:1901360,GO:1901363,GO:1990726,GO:1990904 - 0.00000000006104 66.0
EH2_k127_2606235_12 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000006016 57.0
EH2_k127_2606235_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 295.0
EH2_k127_2606235_3 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008215 268.0
EH2_k127_2606235_4 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000008882 232.0
EH2_k127_2606235_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000006197 171.0
EH2_k127_2606235_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000006912 102.0
EH2_k127_2606235_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000001888 97.0
EH2_k127_2606235_8 Transcriptional regulator PadR-like family - - - 0.00000000000003187 78.0
EH2_k127_2606235_9 - K00960 - 2.7.7.6 0.0000000000001469 70.0
EH2_k127_2685137_0 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008315 282.0
EH2_k127_2685137_1 GDP-mannose dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000001762 225.0
EH2_k127_2685137_2 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000005968 160.0
EH2_k127_2685137_3 HAD-hyrolase-like - - - 0.000005226 55.0
EH2_k127_2736329_0 von Willebrand factor type A domain K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 430.0
EH2_k127_2746469_0 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 344.0
EH2_k127_2746469_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0008966,GO:0016853,GO:0016866,GO:0016868 5.4.2.10 0.0000000000000000000000000000000000000000000000000000001377 201.0
EH2_k127_279122_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008165 257.0
EH2_k127_279122_1 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000106 261.0
EH2_k127_279122_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000002326 210.0
EH2_k127_279122_3 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000001959 138.0
EH2_k127_2853770_0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000002553 192.0
EH2_k127_2853770_1 Serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000427 160.0
EH2_k127_2853770_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000006907 135.0
EH2_k127_2853770_3 Belongs to the GcvP family K00282 - 1.4.4.2 0.00000000000000000000000000005777 118.0
EH2_k127_2853770_4 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000007736 103.0
EH2_k127_2853770_5 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000001285 99.0
EH2_k127_2854628_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.537e-316 983.0
EH2_k127_2854628_1 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 281.0
EH2_k127_2854628_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000001297 189.0
EH2_k127_2854628_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000005017 154.0
EH2_k127_2854628_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000003867 100.0
EH2_k127_2854628_5 Chromate resistance exported protein - - - 0.000000000000000003623 87.0
EH2_k127_288295_0 TIGRFAM glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 400.0
EH2_k127_288295_1 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000006628 228.0
EH2_k127_2884347_0 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000002598 222.0
EH2_k127_2884347_1 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000000000000000001667 208.0
EH2_k127_2896748_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 302.0
EH2_k127_2896748_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003991 267.0
EH2_k127_2896748_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000007339 215.0
EH2_k127_2896748_3 Efflux ABC transporter permease protein K02004 - - 0.00000000000000000000000000000000000000000000407 179.0
EH2_k127_2896748_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000007734 65.0
EH2_k127_2896748_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00001516 49.0
EH2_k127_2968231_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 367.0
EH2_k127_2968231_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002219 257.0
EH2_k127_2968231_2 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000108 236.0
EH2_k127_2968231_3 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000001244 201.0
EH2_k127_2968231_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000003029 96.0
EH2_k127_30422_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 439.0
EH2_k127_30422_1 segregation and condensation protein K06024 - - 0.00000000000000000000000000000000833 134.0
EH2_k127_30422_2 Segregation and condensation protein ScpA K05896 - - 0.00000003194 64.0
EH2_k127_3074337_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 508.0
EH2_k127_3074337_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000382 133.0
EH2_k127_3074337_2 Major Facilitator Superfamily - - - 0.00000000002682 76.0
EH2_k127_307823_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002484 283.0
EH2_k127_307823_1 Glycosyl transferase 4-like - - - 0.0000000000000000000000000001923 128.0
EH2_k127_307823_2 - - - - 0.00000000000000000001585 103.0
EH2_k127_307823_3 methyltransferase - - - 0.00000000000975 75.0
EH2_k127_307823_4 protein conserved in archaea K09723 - - 0.000000000229 68.0
EH2_k127_312839_0 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000001597 171.0
EH2_k127_312839_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000281 177.0
EH2_k127_3144175_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000001532 69.0
EH2_k127_3239186_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 346.0
EH2_k127_3239186_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 320.0
EH2_k127_3239186_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003973 283.0
EH2_k127_3239186_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001269 201.0
EH2_k127_3239186_4 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.00000000000000000000000000000000000000000000000006504 184.0
EH2_k127_3259580_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 492.0
EH2_k127_327583_0 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 315.0
EH2_k127_327583_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 271.0
EH2_k127_327583_2 EamA-like transporter family - - - 0.000000000000000000002467 105.0
EH2_k127_327583_3 phosphate transport K07220 - - 0.00000000000000002212 90.0
EH2_k127_327583_4 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000001148 78.0
EH2_k127_3347742_0 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 455.0
EH2_k127_3347742_1 aminopeptidase K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 381.0
EH2_k127_3347742_2 YoaP-like - - - 0.000000000000000000000000000000000000000000000000000000000003827 221.0
EH2_k127_3347742_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000006966 172.0
EH2_k127_3347742_4 - - - - 0.000000000000000000000000000000000001234 145.0
EH2_k127_3347742_5 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000005573 94.0
EH2_k127_3347742_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.000000000000000005189 87.0
EH2_k127_3347742_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000001115 86.0
EH2_k127_3347742_8 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000006524 72.0
EH2_k127_3347742_9 - K00960 - 2.7.7.6 0.000000006614 59.0
EH2_k127_334991_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 318.0
EH2_k127_334991_1 metallocarboxypeptidase activity K05996 - 3.4.17.18 0.000000000000000000000000000000000000001232 162.0
EH2_k127_334991_2 GIY-YIG catalytic domain K07461 - - 0.0000000000000000832 83.0
EH2_k127_334991_3 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000007732 52.0
EH2_k127_334991_4 cell wall binding repeat - - - 0.0007031 47.0
EH2_k127_3421083_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 1.354e-228 724.0
EH2_k127_3421083_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 485.0
EH2_k127_3421083_10 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000005772 108.0
EH2_k127_3421083_11 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000001345 89.0
EH2_k127_3421083_12 - - - - 0.000000000001182 70.0
EH2_k127_3421083_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 336.0
EH2_k127_3421083_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 330.0
EH2_k127_3421083_4 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.00000000000000000000000000000000000000000000000000000003629 202.0
EH2_k127_3421083_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000000003605 160.0
EH2_k127_3421083_6 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000005643 148.0
EH2_k127_3421083_7 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000001158 132.0
EH2_k127_3421083_8 PFAM PfkB - - - 0.00000000000000000000000000000001419 138.0
EH2_k127_3421083_9 Uncharacterized protein conserved in archaea (DUF2110) - - - 0.000000000000000000000003955 109.0
EH2_k127_3472081_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 550.0
EH2_k127_3472081_1 Hemerythrin HHE cation binding domain protein K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 352.0
EH2_k127_3472081_2 Transcriptional regulator K07108 - - 0.00000008825 55.0
EH2_k127_3474037_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1138.0
EH2_k127_3474037_1 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000004573 222.0
EH2_k127_3474037_2 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000003043 192.0
EH2_k127_3474037_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000002846 183.0
EH2_k127_3481075_0 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000067 161.0
EH2_k127_3481075_1 Zn-ribbon RNA-binding protein with a function in translation - - - 0.000000000000000000000000000000000000001401 161.0
EH2_k127_3481075_2 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000004989 140.0
EH2_k127_3504239_0 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000006794 220.0
EH2_k127_3504239_1 NAD(P)H dehydrogenase (quinone) activity K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000006558 88.0
EH2_k127_3505030_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 348.0
EH2_k127_3505030_1 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000000001435 148.0
EH2_k127_3505030_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000009842 143.0
EH2_k127_3547556_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000007527 244.0
EH2_k127_3547556_1 Involved in galactofuranosyl biosynthesis converts UDO-GlcP to UDP-GalP catalytic activity UDP- glucopyranose UDP-galactopyranose - - - 0.000000000000000000000000000000000000000000000000000000000000001624 230.0
EH2_k127_3547556_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000001001 126.0
EH2_k127_3547556_3 - - - - 0.00000000000001225 81.0
EH2_k127_3561719_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000001108 246.0
EH2_k127_3561719_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000002593 102.0
EH2_k127_3561719_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000006007 81.0
EH2_k127_3561719_3 regulatory protein, arsR - - - 0.0000000000001105 78.0
EH2_k127_358348_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 340.0
EH2_k127_358348_1 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.000000000000000000000000000000000000000000002869 169.0
EH2_k127_3596206_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 573.0
EH2_k127_3596206_1 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 393.0
EH2_k127_3596206_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 388.0
EH2_k127_3596206_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000001263 98.0
EH2_k127_3596206_4 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.000000000235 69.0
EH2_k127_3630494_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 424.0
EH2_k127_3630494_1 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 329.0
EH2_k127_3640471_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 312.0
EH2_k127_3640471_1 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000238 243.0
EH2_k127_3640471_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000001876 134.0
EH2_k127_3640471_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000001281 85.0
EH2_k127_3640471_4 pathogenesis - - - 0.000000000392 69.0
EH2_k127_3681983_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 436.0
EH2_k127_3681983_1 RmlD substrate binding domain K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000001274 163.0
EH2_k127_3681983_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000006027 73.0
EH2_k127_3697579_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 406.0
EH2_k127_3697579_1 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 347.0
EH2_k127_3697789_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 428.0
EH2_k127_3697789_1 RNA-binding protein homologous to eukaryotic snRNP K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000002285 108.0
EH2_k127_3697789_2 Papain family cysteine protease - - - 0.00000000000006488 84.0
EH2_k127_3702092_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 538.0
EH2_k127_3702092_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 390.0
EH2_k127_3702092_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 344.0
EH2_k127_3702092_3 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000001413 163.0
EH2_k127_3702092_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000005375 107.0
EH2_k127_3702092_5 - - - - 0.00000000000001751 82.0
EH2_k127_3702092_6 HTH DNA binding domain - - - 0.00000000004981 67.0
EH2_k127_3702092_8 domain, Protein K01218,K10953,K12516,K15125,K19231 - 3.2.1.78 0.0000006471 61.0
EH2_k127_3702092_9 Domain of unknown function DUF87 K06915 - - 0.0001086 51.0
EH2_k127_3766021_0 Sigma-70, region 4 K03088 - - 0.0000000000000000000000001704 106.0
EH2_k127_3766021_1 ATP-dependent peptidase activity K01338 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 0.0000000000000009228 79.0
EH2_k127_3766021_2 Putative zinc-finger - - - 0.00007967 53.0
EH2_k127_381611_0 DEAD H associated K03724 - - 1.059e-212 694.0
EH2_k127_381611_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000007036 69.0
EH2_k127_381611_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00008333 51.0
EH2_k127_3827855_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 461.0
EH2_k127_3827855_1 Protein of unknown function (DUF1512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 325.0
EH2_k127_3827855_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000237 260.0
EH2_k127_3827855_3 FMN binding - - - 0.000000000000000000000000000000000005078 143.0
EH2_k127_3827855_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000003206 141.0
EH2_k127_3827855_5 metalloendopeptidase activity - - - 0.000002353 55.0
EH2_k127_3882324_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 427.0
EH2_k127_3882324_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000001476 178.0
EH2_k127_3882324_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000001342 78.0
EH2_k127_3882324_3 Transcriptional regulator - - - 0.000186 48.0
EH2_k127_3885488_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001128 280.0
EH2_k127_3885488_1 Phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000002032 182.0
EH2_k127_3885488_2 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000006508 142.0
EH2_k127_3891945_0 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000002384 201.0
EH2_k127_3891945_1 PAC2 family K07159 - - 0.00000000000000000000000000000000005338 139.0
EH2_k127_3891945_2 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000000000387 84.0
EH2_k127_3891945_3 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002528 64.0
EH2_k127_3929937_0 - - - - 0.000000000000000000000000000000000000000000000000002306 199.0
EH2_k127_3929937_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000001812 129.0
EH2_k127_397695_0 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003539 246.0
EH2_k127_397695_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000002784 233.0
EH2_k127_397695_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001769 211.0
EH2_k127_397695_3 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000113 80.0
EH2_k127_4049363_0 methyltransferase activity - - - 0.000000000004425 74.0
EH2_k127_4049363_1 Belongs to the TPP enzyme family - - - 0.0000000004467 74.0
EH2_k127_4049363_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000001315 59.0
EH2_k127_4067208_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000001138 226.0
EH2_k127_4067208_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000001674 155.0
EH2_k127_4067208_2 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000001323 129.0
EH2_k127_4101858_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 428.0
EH2_k127_4101858_1 Fumarate hydratase K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 302.0
EH2_k127_4101858_2 Fe-S type, tartrate fumarate subfamily, beta K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
EH2_k127_4101858_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000004576 147.0
EH2_k127_4101858_4 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000002609 124.0
EH2_k127_4101858_5 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000002473 107.0
EH2_k127_4101858_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000002768 75.0
EH2_k127_4101858_7 - - - - 0.0002385 49.0
EH2_k127_4113565_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000001995 102.0
EH2_k127_4118285_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 456.0
EH2_k127_4118285_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 317.0
EH2_k127_4118285_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 301.0
EH2_k127_4118285_3 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000004112 116.0
EH2_k127_4140401_0 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000000000000000000000000000000000000000000002161 214.0
EH2_k127_4140401_1 Protein of unknown function (DUF998) - - - 0.0000000000001176 78.0
EH2_k127_414530_0 DNA polymerase K02319 - 2.7.7.7 1.861e-231 749.0
EH2_k127_414530_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000002669 65.0
EH2_k127_4158608_0 PFAM transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 388.0
EH2_k127_4158608_1 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000001942 190.0
EH2_k127_4158608_2 - - - - 0.00000000000000000000005155 106.0
EH2_k127_4158608_3 COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.00000000002681 72.0
EH2_k127_4196978_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 491.0
EH2_k127_4196978_1 Pantothenate synthetase K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 286.0
EH2_k127_4196978_2 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000009736 209.0
EH2_k127_4196978_3 PFAM type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000002381 192.0
EH2_k127_4196978_4 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.000000000000000265 83.0
EH2_k127_4240378_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 478.0
EH2_k127_4240378_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000004914 62.0
EH2_k127_4240378_2 - - - - 0.0005322 47.0
EH2_k127_4332615_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000002204 174.0
EH2_k127_4332615_1 - - - - 0.000003798 58.0
EH2_k127_4355683_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 359.0
EH2_k127_4355683_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003823 241.0
EH2_k127_4355683_2 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000002755 76.0
EH2_k127_4355683_3 ribosomal protein S30 K02983 - - 0.0000000001592 63.0
EH2_k127_4387383_0 Dehydrogenase K00111,K15736 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 438.0
EH2_k127_4387383_1 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000002796 225.0
EH2_k127_4446211_0 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000003607 112.0
EH2_k127_4446211_1 CARDB - - - 0.00000000002817 77.0
EH2_k127_4471291_0 Pyruvate formate lyase-like K00656 - 2.3.1.54 2.133e-199 628.0
EH2_k127_4471291_1 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 339.0
EH2_k127_4471291_2 transporter K07238 - - 0.0000000000000000000000000000000000004548 148.0
EH2_k127_4514488_0 Glycosyl transferase family 21 K11936 - - 0.00000000000000000000000002926 124.0
EH2_k127_4514488_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K06976 - - 0.000000001901 68.0
EH2_k127_4514488_2 Transcriptional regulator - - - 0.00000001017 61.0
EH2_k127_4514488_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00005705 54.0
EH2_k127_4544243_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009743 270.0
EH2_k127_4544243_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001405 244.0
EH2_k127_4544243_2 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000002145 218.0
EH2_k127_4544243_3 Adenosine/AMP deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000000000000004664 202.0
EH2_k127_4544243_4 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000002587 140.0
EH2_k127_4549445_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 6.024e-234 734.0
EH2_k127_4549445_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 554.0
EH2_k127_4549445_10 Acetyltransferase (GNAT) domain K22441 - 2.3.1.57 0.000005952 54.0
EH2_k127_4549445_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 464.0
EH2_k127_4549445_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 397.0
EH2_k127_4549445_4 PFAM S-layer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008555 262.0
EH2_k127_4549445_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000004124 244.0
EH2_k127_4549445_6 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000004579 145.0
EH2_k127_4549445_7 N2,N2-dimethylguanosine tRNA methyltransferase K15429 - 2.1.1.228 0.000000000000000000002934 98.0
EH2_k127_4549445_8 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000008707 82.0
EH2_k127_4549445_9 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000432 70.0
EH2_k127_4567290_0 hydrolase (HAD superfamily) K07025 - - 0.00000000000000000000000000006244 125.0
EH2_k127_4567290_1 Phage integrase family - - - 0.0006108 48.0
EH2_k127_4611437_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000003719 83.0
EH2_k127_4612310_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 3.309e-281 876.0
EH2_k127_4612310_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.495e-243 781.0
EH2_k127_4612310_2 GPR1 FUN34 yaaH family protein K07034 - - 0.000000000000000000000000000000000000000000000000000000001111 206.0
EH2_k127_4612310_3 HAD-hyrolase-like K07025 - - 0.0000000000000002257 90.0
EH2_k127_4612310_4 Periplasmic copper-binding protein (NosD) - - - 0.00003364 50.0
EH2_k127_4614007_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 550.0
EH2_k127_4614007_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 368.0
EH2_k127_4614007_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000002878 196.0
EH2_k127_4614007_3 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000006061 184.0
EH2_k127_4614007_4 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000004542 120.0
EH2_k127_4614007_5 PIN domain of ribonuclease K07060 - - 0.0000000000000000000004974 100.0
EH2_k127_4614007_6 FR47-like protein - - - 0.00000000000101 74.0
EH2_k127_4614007_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000003123 66.0
EH2_k127_4614007_8 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0001846 44.0
EH2_k127_4614288_0 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004509 262.0
EH2_k127_4614288_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000973 121.0
EH2_k127_4614288_2 Transcriptional regulator K07108,K22206 - - 0.00000000000004348 78.0
EH2_k127_4614288_3 monooxygenase activity K06966,K07089,K07402 - 3.2.2.10 0.00000000188 63.0
EH2_k127_4620126_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000001601 123.0
EH2_k127_4628470_0 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000001227 137.0
EH2_k127_4628470_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000008461 85.0
EH2_k127_4628470_2 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000002722 73.0
EH2_k127_4628470_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000778 46.0
EH2_k127_4654463_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000003547 249.0
EH2_k127_4654463_1 PFAM DNA polymerase, beta domain protein region K09717 - - 0.000000000000000000000000000002451 128.0
EH2_k127_4654463_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000001728 99.0
EH2_k127_4654463_3 PFAM DNA polymerase, beta domain protein region K09717 - - 0.0000000000000869 83.0
EH2_k127_4654463_4 - K09717 - - 0.0000002994 62.0
EH2_k127_4704229_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 356.0
EH2_k127_4704229_1 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005635 285.0
EH2_k127_4704229_2 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000001014 254.0
EH2_k127_4704229_3 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000003194 226.0
EH2_k127_4744259_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 331.0
EH2_k127_4744938_0 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 594.0
EH2_k127_4744938_1 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 495.0
EH2_k127_4744938_10 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000006583 115.0
EH2_k127_4744938_11 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000006174 104.0
EH2_k127_4744938_12 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000006866 106.0
EH2_k127_4744938_13 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000000004784 82.0
EH2_k127_4744938_14 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - - 0.000000000000009763 85.0
EH2_k127_4744938_15 - - - - 0.0000007924 55.0
EH2_k127_4744938_17 - - - - 0.0001671 49.0
EH2_k127_4744938_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 430.0
EH2_k127_4744938_3 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 315.0
EH2_k127_4744938_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006254 285.0
EH2_k127_4744938_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000008729 236.0
EH2_k127_4744938_6 F420-0:Gamma-glutamyl ligase - - - 0.000000000000000000000000000000000000000000824 167.0
EH2_k127_4744938_7 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000009559 147.0
EH2_k127_4744938_8 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000001364 149.0
EH2_k127_4744938_9 AraC-like ligand binding domain - - - 0.0000000000000000000000000000005669 128.0
EH2_k127_4804208_0 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000032 188.0
EH2_k127_4804208_1 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000001248 168.0
EH2_k127_4804208_2 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000002261 164.0
EH2_k127_4804208_3 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000008016 148.0
EH2_k127_4804208_4 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000005915 117.0
EH2_k127_4804208_5 Acetyltransferase (GNAT) family - - - 0.000000000001004 77.0
EH2_k127_4804208_6 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000003583 51.0
EH2_k127_4804208_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000006943 58.0
EH2_k127_4814989_0 RimK-like ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 301.0
EH2_k127_4814989_1 Glutamate-cysteine ligase family 2(GCS2) - - - 0.00000000000000000000000000000000000000000000001032 176.0
EH2_k127_4814989_2 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000000001892 155.0
EH2_k127_4877588_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.805e-256 813.0
EH2_k127_4877588_1 ferredoxin oxidoreductase, subunit alpha K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 403.0
EH2_k127_4877588_2 ferredoxin oxidoreductase, subunit beta K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 304.0
EH2_k127_4877588_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
EH2_k127_4877588_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000013 208.0
EH2_k127_4877588_5 PFAM Pyruvate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000239 153.0
EH2_k127_4877588_6 KaiC - - - 0.000000000000000000000000000000000001658 147.0
EH2_k127_4877588_7 metallopeptidase activity - - - 0.00000001417 68.0
EH2_k127_4877588_8 Winged helix-turn-helix - - - 0.000182 49.0
EH2_k127_4889439_0 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
EH2_k127_4889439_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000001369 209.0
EH2_k127_4889439_2 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000003159 199.0
EH2_k127_4889439_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000001108 82.0
EH2_k127_4889439_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0009325 46.0
EH2_k127_4913797_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 379.0
EH2_k127_4913797_1 protein, putative amidase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000002802 183.0
EH2_k127_4913797_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000007439 73.0
EH2_k127_4913797_3 helix_turn_helix ASNC type - - - 0.0000000001 64.0
EH2_k127_4921351_0 GAF domain - - - 0.0000000000000000000000000000000000000000003661 181.0
EH2_k127_4921351_1 response regulator, receiver K07669 - - 0.00000000000000000000000000006045 121.0
EH2_k127_4921351_2 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.0000001774 62.0
EH2_k127_4925621_0 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000254 211.0
EH2_k127_4925621_1 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000003939 169.0
EH2_k127_4925621_2 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000001119 115.0
EH2_k127_4925621_3 SMART Nucleotide binding protein, PINc K07158 - - 0.0000000000000000004866 91.0
EH2_k127_4925621_4 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000004324 80.0
EH2_k127_4925621_5 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000381 76.0
EH2_k127_4925621_6 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000001476 73.0
EH2_k127_4925621_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001037 70.0
EH2_k127_4925621_8 - - - - 0.0003671 48.0
EH2_k127_4988233_0 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 603.0
EH2_k127_4988233_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 388.0
EH2_k127_4988233_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000001151 238.0
EH2_k127_4988233_3 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000008171 211.0
EH2_k127_4988233_4 Cupin domain - - - 0.00000000000000000000000000000000000002247 146.0
EH2_k127_4989503_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.22e-313 986.0
EH2_k127_5043259_0 SMART Elongator protein 3 MiaB NifB K06935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 311.0
EH2_k127_5043259_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.0000000000000000000036 96.0
EH2_k127_5043259_2 Peptidase family S41 - - - 0.0000000000000001257 88.0
EH2_k127_5065391_0 - - - - 0.0000000000000000000000000000000000000000000000000000000001444 216.0
EH2_k127_5065391_1 heme binding - - - 0.00000000000000000000000000000000000000000000000000126 196.0
EH2_k127_5065391_2 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000000000004431 140.0
EH2_k127_5065391_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000001173 111.0
EH2_k127_5065391_4 Periplasmic copper-binding protein (NosD) - - - 0.000000000724 63.0
EH2_k127_5094993_0 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 515.0
EH2_k127_5094993_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 481.0
EH2_k127_5116668_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.402e-223 709.0
EH2_k127_5116668_1 Dehydrogenase K00111,K15736 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 445.0
EH2_k127_5116668_2 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 402.0
EH2_k127_5116668_3 GTPase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 313.0
EH2_k127_5116668_4 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000017 202.0
EH2_k127_5116668_5 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000001432 199.0
EH2_k127_5116668_6 Mechanosensitive ion channel K05802 - - 0.00000000000000001952 93.0
EH2_k127_5116668_7 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000006262 77.0
EH2_k127_5190187_0 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 511.0
EH2_k127_5215379_0 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000009776 241.0
EH2_k127_5215379_1 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000006464 147.0
EH2_k127_5215379_2 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000007782 89.0
EH2_k127_5215379_3 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000335 82.0
EH2_k127_5215379_4 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000001696 52.0
EH2_k127_5351274_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 622.0
EH2_k127_5351274_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 451.0
EH2_k127_5351274_2 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 267.0
EH2_k127_5351274_3 D-aminopeptidase K16203 - - 0.0000000000000000000000009185 113.0
EH2_k127_535696_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 302.0
EH2_k127_535696_1 RNA-binding protein homologous to eukaryotic snRNP K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 294.0
EH2_k127_535696_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000009397 244.0
EH2_k127_535696_3 Fe-S cluster K04488 - - 0.000000000000000000000000000000000000000000000000000000002529 206.0
EH2_k127_538792_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000001369 209.0
EH2_k127_538792_1 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000001773 185.0
EH2_k127_5399808_0 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 318.0
EH2_k127_5399808_1 Zn-dependent hydrolase, glyoxylase - - - 0.00000000000000000000000000000000000000000000000002154 184.0
EH2_k127_5399808_2 Nitroreductase family - - - 0.00000000000000000000000000000000000001542 153.0
EH2_k127_5399808_3 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000006156 70.0
EH2_k127_5399808_4 AMP-binding enzyme. Source PGD - - - 0.0000002742 54.0
EH2_k127_5428948_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000003917 203.0
EH2_k127_5428948_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000001174 164.0
EH2_k127_5428948_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00003276 57.0
EH2_k127_5430810_0 - - - - 0.000000000000000000000000000000000000000002332 166.0
EH2_k127_5430810_1 NADPH-dependent FMN reductase - - - 0.000000000000000000001468 100.0
EH2_k127_5450226_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.684e-292 912.0
EH2_k127_5450226_1 PFAM Rubredoxin - - - 0.0000000000000000000001136 97.0
EH2_k127_548990_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.198e-234 741.0
EH2_k127_548990_1 RmlD substrate binding domain K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 452.0
EH2_k127_548990_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 424.0
EH2_k127_548990_3 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 322.0
EH2_k127_548990_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000002809 207.0
EH2_k127_548990_5 PFAM SNARE associated Golgi protein - - - 0.000001232 54.0
EH2_k127_5541032_0 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 356.0
EH2_k127_5541032_1 Peptidase family M50 - - - 0.0000000000000000001741 93.0
EH2_k127_5541032_2 Diphthamide synthase K06927 - 6.3.1.14 0.000000000001678 69.0
EH2_k127_5571738_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 7.204e-291 908.0
EH2_k127_5571738_1 PP-loop family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005635 271.0
EH2_k127_5571738_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000004671 229.0
EH2_k127_5571738_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
EH2_k127_5571738_4 DNA polymerase beta domain protein region K07073 - - 0.0000000000000000000000000000000000000000000000000000000000008016 218.0
EH2_k127_5571738_5 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000003395 208.0
EH2_k127_5571738_6 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000834 120.0
EH2_k127_5571738_7 - - - - 0.00006664 48.0
EH2_k127_5571738_8 - - - - 0.0005617 48.0
EH2_k127_5685187_0 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000001803 204.0
EH2_k127_5685187_1 Inorganic pyrophosphatase - - - 0.0000000000000000000003101 98.0
EH2_k127_5685187_2 Psort location Cytoplasmic, score 8.96 K01507 - 3.6.1.1 0.000004199 50.0
EH2_k127_5685187_3 Hypothetical methyltransferase - - - 0.00005792 53.0
EH2_k127_5685187_4 - - - - 0.0003329 49.0
EH2_k127_5688953_0 Heat shock 70 kDa protein K04043 - - 2.203e-240 753.0
EH2_k127_5688953_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 289.0
EH2_k127_5688953_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001638 244.0
EH2_k127_5688953_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000001001 126.0
EH2_k127_5701527_0 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 433.0
EH2_k127_5701527_1 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00018 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26,1.1.1.29 0.00000000000000000000000000000000000000000002607 164.0
EH2_k127_5701527_2 ThiS family K03636 - - 0.0000000003584 64.0
EH2_k127_5764798_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000003223 243.0
EH2_k127_5764798_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000006137 132.0
EH2_k127_5764798_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001365 130.0
EH2_k127_5764798_3 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001572 126.0
EH2_k127_5768599_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000001391 199.0
EH2_k127_5768599_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000002898 118.0
EH2_k127_5768599_2 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000004424 83.0
EH2_k127_5769654_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 599.0
EH2_k127_5769654_1 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 414.0
EH2_k127_5769654_2 PFAM Hydrogenase formation HypD protein K04654 - - 0.0000000000000000000000000000000000000000003724 162.0
EH2_k127_5814387_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000201 218.0
EH2_k127_5814387_1 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000000001649 163.0
EH2_k127_5814387_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000005394 99.0
EH2_k127_5888495_0 RNA polymerase subunit 9 K03057 - - 0.000000000000000005795 84.0
EH2_k127_5888495_1 domain protein - - - 0.0000000003702 67.0
EH2_k127_5913622_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 385.0
EH2_k127_5913622_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006331 241.0
EH2_k127_5913622_2 May be involved in the transport of PQQ or its precursor to the periplasm K06167 - 3.1.4.55 0.000000000000000000000000000000000009459 147.0
EH2_k127_5913622_3 Right handed beta helix region - - - 0.00000000000000000000000000009139 135.0
EH2_k127_5913622_4 OsmC-like protein K07397 - - 0.00000000000000000000000005573 113.0
EH2_k127_5913622_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000001845 111.0
EH2_k127_5913622_6 Src homology 3 domains - - - 0.00000000000000000005727 93.0
EH2_k127_5913622_7 EamA-like transporter family - - - 0.000000008854 62.0
EH2_k127_5924123_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.539e-206 654.0
EH2_k127_5924123_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 340.0
EH2_k127_5924123_2 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 311.0
EH2_k127_5924123_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06951 - - 0.0000000000000000000000000000000000000000000297 171.0
EH2_k127_5924123_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000004485 158.0
EH2_k127_5924123_5 ParB-like nuclease domain K03497 - - 0.000000000000000000000000002106 124.0
EH2_k127_5924123_6 integral membrane protein K07027 - - 0.0000004661 61.0
EH2_k127_5954422_0 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 415.0
EH2_k127_5954422_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000002676 245.0
EH2_k127_5954422_2 E1 component K21416 - - 0.000000000000000000000000000000002701 131.0
EH2_k127_6060144_0 Domain of unknown function (DUF4438) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 351.0
EH2_k127_6060144_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000003767 138.0
EH2_k127_6060144_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000003253 130.0
EH2_k127_6060144_3 ribosomal protein K02976 - - 0.00000000000000000000000000001554 119.0
EH2_k127_6060144_4 Domain of unknown function (DUF1805) - - - 0.00000000000000000001768 93.0
EH2_k127_6060144_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00007035 49.0
EH2_k127_6081427_0 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000000002923 186.0
EH2_k127_6081427_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000002119 163.0
EH2_k127_6095387_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 601.0
EH2_k127_6095387_1 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 530.0
EH2_k127_6095387_2 PFAM Oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005656 264.0
EH2_k127_6095387_3 PFAM Methyl-viologen-reducing hydrogenase, delta subunit K22480 - 1.8.7.3 0.000000001024 60.0
EH2_k127_6100727_0 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000000000002997 176.0
EH2_k127_6100727_1 aminopeptidase activity K19689 - - 0.00000000000000002063 93.0
EH2_k127_6203049_0 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 379.0
EH2_k127_6203049_1 Haloacid dehalogenase-like hydrolase K01560,K07025 - 3.8.1.2 0.00000000000000000008584 98.0
EH2_k127_6204593_0 Zn_pept K05996 - 3.4.17.18 0.00000000000000000000000000002225 137.0
EH2_k127_6204593_1 PFAM band 7 protein - - - 0.000000000000000000000000002447 117.0
EH2_k127_6204593_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000001415 82.0
EH2_k127_6207217_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 494.0
EH2_k127_6207217_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 341.0
EH2_k127_6207217_2 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001207 112.0
EH2_k127_6207217_3 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000001822 91.0
EH2_k127_6207217_4 PAC2 family K06869 - - 0.000000000000004019 79.0
EH2_k127_6215537_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
EH2_k127_6215537_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000001134 181.0
EH2_k127_6215537_10 Thermolysin metallopeptidase, alpha-helical domain K20273 - - 0.0004084 55.0
EH2_k127_6215537_2 Thioredoxin K03671 - - 0.000000000000000000000000000000003716 138.0
EH2_k127_6215537_3 - - - - 0.000000000000000000002336 97.0
EH2_k127_6215537_4 helix_turn_helix ASNC type K03719 - - 0.00000000000000000009274 96.0
EH2_k127_6215537_5 - - - - 0.00000000000009916 79.0
EH2_k127_6215537_6 PKD domain containing protein - - - 0.0000000000005969 84.0
EH2_k127_6215537_7 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000006789 70.0
EH2_k127_6215537_8 Peptidase C13 family - - - 0.00000008135 67.0
EH2_k127_6215537_9 S-layer homology domain - - - 0.000002815 59.0
EH2_k127_6224735_0 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000001716 190.0
EH2_k127_6224735_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000001906 133.0
EH2_k127_6224735_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.0000000000000000003577 91.0
EH2_k127_6224735_3 Ribonuclease III - - - 0.0000000000000002168 84.0
EH2_k127_6224735_4 methyltransferase small K07579 - - 0.0000000000003581 74.0
EH2_k127_6224735_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000002986 61.0
EH2_k127_6239290_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 505.0
EH2_k127_6239290_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 382.0
EH2_k127_6239290_2 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 363.0
EH2_k127_6239290_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005496 266.0
EH2_k127_6239290_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000008683 232.0
EH2_k127_6239290_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000004851 177.0
EH2_k127_6239290_6 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000228 169.0
EH2_k127_6239290_7 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000001402 166.0
EH2_k127_6239290_8 - - - - 0.00000001402 61.0
EH2_k127_6239290_9 - - - - 0.0000005363 57.0
EH2_k127_6319098_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 308.0
EH2_k127_6319098_1 - - - - 0.0000000000000133 82.0
EH2_k127_6323360_0 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 571.0
EH2_k127_6323360_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 369.0
EH2_k127_6323923_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 524.0
EH2_k127_6323923_1 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000004509 207.0
EH2_k127_637015_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 590.0
EH2_k127_637015_1 synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 317.0
EH2_k127_637015_10 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000002247 134.0
EH2_k127_637015_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000006425 109.0
EH2_k127_637015_12 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000008536 115.0
EH2_k127_637015_13 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000001174 110.0
EH2_k127_637015_14 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000001925 102.0
EH2_k127_637015_15 PFAM transferase hexapeptide repeat containing protein - - - 0.00000009685 55.0
EH2_k127_637015_2 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001963 302.0
EH2_k127_637015_3 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004166 263.0
EH2_k127_637015_4 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000562 212.0
EH2_k127_637015_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000207 207.0
EH2_k127_637015_6 Putative RNA methyltransferase K09142 - - 0.000000000000000000000000000000000000000000000000000000004184 209.0
EH2_k127_637015_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000003625 201.0
EH2_k127_637015_8 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001499 193.0
EH2_k127_637015_9 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000001482 147.0
EH2_k127_6379396_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.043e-297 931.0
EH2_k127_6379396_1 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000002248 261.0
EH2_k127_6379396_2 Methyltransferase K07579 - - 0.0000000000000001524 84.0
EH2_k127_648491_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.449e-220 701.0
EH2_k127_648491_1 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000004369 81.0
EH2_k127_648491_2 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000004266 58.0
EH2_k127_6541534_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.479e-250 782.0
EH2_k127_6541534_1 in RNase L inhibitor, RLI K06174 - - 7.25e-205 653.0
EH2_k127_6541534_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000002604 180.0
EH2_k127_6541534_11 THUMP domain K06963 - - 0.000000000000000000000000001094 119.0
EH2_k127_6541534_12 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000005787 106.0
EH2_k127_6541534_13 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000003817 71.0
EH2_k127_6541534_14 KEOPS complex Cgi121-like subunit K09119 - - 0.000000128 60.0
EH2_k127_6541534_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 484.0
EH2_k127_6541534_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 470.0
EH2_k127_6541534_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 328.0
EH2_k127_6541534_5 Glutamate formiminotransferase K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 295.0
EH2_k127_6541534_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 258.0
EH2_k127_6541534_7 asparaginase activity K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000006297 238.0
EH2_k127_6541534_8 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000001552 221.0
EH2_k127_6541534_9 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000102 181.0
EH2_k127_6553965_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000008745 238.0
EH2_k127_6553965_1 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000002086 188.0
EH2_k127_6590856_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 402.0
EH2_k127_6595523_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000004823 197.0
EH2_k127_6595523_1 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.0000000000002967 76.0
EH2_k127_669373_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 6.743e-227 725.0
EH2_k127_669373_1 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 463.0
EH2_k127_669373_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 305.0
EH2_k127_669373_3 NOL1 NOP2 sun family - - - 0.0000000000000000000000000000000000000000000000000218 190.0
EH2_k127_669373_4 Lysine exporter LysO - - - 0.00000000000000000000000000000008649 132.0
EH2_k127_669373_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000001171 97.0
EH2_k127_669373_6 - - - - 0.0003775 52.0
EH2_k127_669373_7 Lysine exporter LysO - - - 0.0006758 48.0
EH2_k127_6737012_0 GTPase of K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 437.0
EH2_k127_6737012_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000003258 230.0
EH2_k127_6743314_0 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 301.0
EH2_k127_6743314_1 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000008399 175.0
EH2_k127_6743314_2 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000002002 62.0
EH2_k127_6743314_3 HxlR-like helix-turn-helix - - - 0.00000001095 63.0
EH2_k127_6743314_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000214 55.0
EH2_k127_6743314_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00002283 49.0
EH2_k127_6752927_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 367.0
EH2_k127_6752927_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 338.0
EH2_k127_6752927_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 304.0
EH2_k127_6752927_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000002589 231.0
EH2_k127_6789166_0 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000000000000000000000000000000000000000000001471 234.0
EH2_k127_6789166_1 FR47-like protein - - - 0.00004683 51.0
EH2_k127_6805628_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000007735 269.0
EH2_k127_6805628_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000009446 85.0
EH2_k127_6832035_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 499.0
EH2_k127_6832035_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 310.0
EH2_k127_6832035_10 Binds to the 23S rRNA K02921 - - 0.00000000000000001128 86.0
EH2_k127_6832035_11 - - - - 0.00000000000003408 76.0
EH2_k127_6832035_12 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.00000000003209 68.0
EH2_k127_6832035_13 Major facilitator superfamily - - - 0.00000009073 64.0
EH2_k127_6832035_14 Protein of unknown function (DUF3194) - - - 0.00002735 50.0
EH2_k127_6832035_2 ABC-type cobalt transport system ATPase component K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 293.0
EH2_k127_6832035_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008208 271.0
EH2_k127_6832035_4 PFAM ABC transporter related K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008795 260.0
EH2_k127_6832035_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000201 223.0
EH2_k127_6832035_6 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000217 209.0
EH2_k127_6832035_7 DHH family - - - 0.00000000000000000000000000000000000000000000000005407 190.0
EH2_k127_6832035_8 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.00000000000000000000000000000000000004643 146.0
EH2_k127_6832035_9 PFAM Cobalt transport protein K16785 - - 0.00000000000000000000000000000000001279 146.0
EH2_k127_6846860_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 323.0
EH2_k127_6846860_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000369 206.0
EH2_k127_6846860_2 Dolichyl-phosphate beta-D-mannosyltransferase K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000004342 171.0
EH2_k127_6846860_3 Glycosyl transferase family group 2 - - - 0.0000000000000000000000003572 118.0
EH2_k127_6846860_4 methyltransferase - - - 0.0000000002259 67.0
EH2_k127_6881189_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 329.0
EH2_k127_691481_0 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000001192 255.0
EH2_k127_691481_1 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000008775 196.0
EH2_k127_691481_2 DNA polymerase K02319 - 2.7.7.7 0.000000000000000000000000000000159 132.0
EH2_k127_6958422_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 370.0
EH2_k127_6958422_1 glutamyl-tRNA reductase activity K02407,K02492,K10714,K15671 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.00000000000000000000000000000000000000001548 168.0
EH2_k127_6958422_2 bis(5'-adenosyl)-triphosphatase activity K02503 - - 0.00000000000000000000000000000006349 127.0
EH2_k127_6958422_3 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000002537 117.0
EH2_k127_6958422_4 Abortive infection protein K07052 - - 0.0000001997 62.0
EH2_k127_6958422_5 - - - - 0.000003718 57.0
EH2_k127_6959991_0 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 297.0
EH2_k127_6959991_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 282.0
EH2_k127_6959991_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000003911 50.0
EH2_k127_6981803_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 559.0
EH2_k127_6981803_1 PFAM aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 455.0
EH2_k127_6981803_2 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000002987 169.0
EH2_k127_6981803_3 Hydrolase TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000001254 149.0
EH2_k127_6981803_4 Cyclophilin-like K09143 - - 0.00000000000000000000000008615 111.0
EH2_k127_6981803_5 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.000000000000007758 76.0
EH2_k127_6981803_6 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.00000000001717 67.0
EH2_k127_6981803_7 30S ribosomal protein S25E K02975 - - 0.00000007665 58.0
EH2_k127_7000927_0 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000001594 184.0
EH2_k127_7000927_1 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000003408 152.0
EH2_k127_7000927_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000007585 138.0
EH2_k127_7017949_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000002289 249.0
EH2_k127_7017949_1 protein conserved in archaea K09723 - - 0.000000000008085 73.0
EH2_k127_7017949_2 binds to the 23S rRNA K02929 - - 0.00000000005891 63.0
EH2_k127_7041221_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 3.943e-212 676.0
EH2_k127_7041221_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000008074 160.0
EH2_k127_7041221_2 GYD domain - - - 0.000000000000000000000000000000002156 132.0
EH2_k127_7041221_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000009727 93.0
EH2_k127_7041221_4 Transcription factor Pcc1 K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000001012 57.0
EH2_k127_7041221_5 Protein of unknown function (DUF3194) - - - 0.000002799 53.0
EH2_k127_7041221_6 PFAM phosphoesterase, RecJ domain protein - - - 0.0000368 49.0
EH2_k127_7115727_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 3.37e-246 777.0
EH2_k127_7115727_1 Acetyltransferase (GNAT) family - - - 0.00008125 51.0
EH2_k127_7128784_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 2.822e-210 663.0
EH2_k127_7128784_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 521.0
EH2_k127_7143412_0 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001891 290.0
EH2_k127_7143412_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000004681 241.0
EH2_k127_7143412_2 GrpB protein - - - 0.000000000000000000000000000000001901 135.0
EH2_k127_7143412_3 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000009668 79.0
EH2_k127_7143412_4 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.0002309 48.0
EH2_k127_7211065_0 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000013 289.0
EH2_k127_7259517_0 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 311.0
EH2_k127_7259517_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000356 252.0
EH2_k127_7259517_2 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.000001289 53.0
EH2_k127_7259517_3 PFAM ABC-2 type transporter K01992 - - 0.000001444 58.0
EH2_k127_7270167_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.363e-248 796.0
EH2_k127_7270167_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 349.0
EH2_k127_7270167_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000003502 124.0
EH2_k127_7270167_3 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000007059 103.0
EH2_k127_7270167_4 FUN14 family - - - 0.0000000000002135 74.0
EH2_k127_7275283_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 617.0
EH2_k127_7275283_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000007658 227.0
EH2_k127_7275283_2 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000003765 121.0
EH2_k127_7275283_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.000000000041 67.0
EH2_k127_7320579_0 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 430.0
EH2_k127_7320579_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000004328 225.0
EH2_k127_7339896_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1089.0
EH2_k127_7339896_1 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 475.0
EH2_k127_7339896_10 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001454 207.0
EH2_k127_7339896_11 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000001984 200.0
EH2_k127_7339896_12 PFAM Pyruvate K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000008536 194.0
EH2_k127_7339896_13 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000001554 175.0
EH2_k127_7339896_14 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000009504 161.0
EH2_k127_7339896_15 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000003822 113.0
EH2_k127_7339896_16 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000002559 108.0
EH2_k127_7339896_17 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000002084 102.0
EH2_k127_7339896_18 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000002931 79.0
EH2_k127_7339896_19 - - - - 0.0000001043 56.0
EH2_k127_7339896_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 343.0
EH2_k127_7339896_20 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K22441 - 2.3.1.57 0.0000001495 60.0
EH2_k127_7339896_3 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 332.0
EH2_k127_7339896_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 316.0
EH2_k127_7339896_5 dihydrodipicolinate reductase K03340,K21672 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.4.1.12,1.4.1.16,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 299.0
EH2_k127_7339896_6 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 291.0
EH2_k127_7339896_7 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000014 278.0
EH2_k127_7339896_8 TIGRFAM MIP family channel K02440,K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006961 269.0
EH2_k127_7339896_9 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000928 226.0
EH2_k127_7397646_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 432.0
EH2_k127_7411055_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 432.0
EH2_k127_7411055_1 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 408.0
EH2_k127_7411055_2 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000652 304.0
EH2_k127_7411055_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000001077 224.0
EH2_k127_7411055_4 PAC2 family K07159 - - 0.00000000000000000000000000000000000000001344 165.0
EH2_k127_7411055_5 PFAM Like-Sm ribonucleoprotein, core - - - 0.00000000000000000000002404 104.0
EH2_k127_7411055_6 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000002541 102.0
EH2_k127_7411055_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000001499 91.0
EH2_k127_7411055_8 N-acetyltransferase - - - 0.00000000006495 70.0
EH2_k127_7467719_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 2.131e-313 995.0
EH2_k127_7467719_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 587.0
EH2_k127_7467719_10 Transcription elongation factor Elf1 like - - - 0.000000000001562 70.0
EH2_k127_7467719_11 Sec61beta family - - - 0.00000003902 57.0
EH2_k127_7467719_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 424.0
EH2_k127_7467719_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 337.0
EH2_k127_7467719_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000001053 270.0
EH2_k127_7467719_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000114 231.0
EH2_k127_7467719_6 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000002153 213.0
EH2_k127_7467719_7 membrane K08979 - - 0.0000000000000000000000000000000000000002797 169.0
EH2_k127_7467719_8 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000000000000000501 124.0
EH2_k127_7467719_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000003577 91.0
EH2_k127_7482742_0 Fumarate hydratase K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 306.0
EH2_k127_7482742_1 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000005698 211.0
EH2_k127_7482742_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000001194 75.0
EH2_k127_7485762_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 475.0
EH2_k127_7485762_1 Protein of unknown function (DUF3795) - - - 0.00000003371 58.0
EH2_k127_7494235_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000004329 227.0
EH2_k127_7494235_1 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000000001292 205.0
EH2_k127_7494235_2 - K07092 - - 0.00000000000000000000000000000000000000000000002592 172.0
EH2_k127_7494235_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000004116 96.0
EH2_k127_7494235_4 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.00004024 51.0
EH2_k127_7544635_0 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 288.0
EH2_k127_7544635_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000003143 229.0
EH2_k127_7544635_2 GNAT acetyltransferase - - - 0.000000000000000000000000000000000000000000000000006521 195.0
EH2_k127_7544635_3 PFAM amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000001708 168.0
EH2_k127_7544635_4 Domain of unknown function (DUF4332) - - - 0.00000000000003783 82.0
EH2_k127_7544635_5 Domain of unknown function (DUF362) - - - 0.00000000003085 75.0
EH2_k127_7555274_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000002982 218.0
EH2_k127_7555274_1 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000000003539 113.0
EH2_k127_756155_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 518.0
EH2_k127_756155_1 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000000000007691 164.0
EH2_k127_756155_2 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000000000000006705 113.0
EH2_k127_756155_3 - - - - 0.000000000000000000000002145 111.0
EH2_k127_756155_4 AAA domain - - - 0.0000000000000001675 94.0
EH2_k127_756155_5 Structural maintenance of chromosomes protein - - - 0.00000000000000272 90.0
EH2_k127_7578712_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 380.0
EH2_k127_7578712_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 316.0
EH2_k127_7578712_2 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000001586 173.0
EH2_k127_7578712_3 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000004227 157.0
EH2_k127_7578712_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000308 132.0
EH2_k127_7578712_5 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000001803 93.0
EH2_k127_7578712_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042182,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046872,GO:0046914,GO:0051186,GO:0051596,GO:0061727,GO:0071704,GO:1901564,GO:1901575,GO:1901615 4.4.1.5 0.00000000000002527 78.0
EH2_k127_7578712_7 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000001525 60.0
EH2_k127_7578712_8 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000063 60.0
EH2_k127_7578712_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000003517 57.0
EH2_k127_7591407_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 542.0
EH2_k127_7591407_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000003419 217.0
EH2_k127_7591407_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000005464 218.0
EH2_k127_7591407_3 PFAM Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.00000000000000000000000000000000000000003534 171.0
EH2_k127_7597750_0 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 1.734e-214 686.0
EH2_k127_7597750_1 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 1.367e-198 629.0
EH2_k127_7597750_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 349.0
EH2_k127_7597750_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 340.0
EH2_k127_7597750_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000002061 192.0
EH2_k127_7597750_5 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000000123 135.0
EH2_k127_7597750_6 PFAM bifunctional deaminase-reductase domain protein K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000004422 83.0
EH2_k127_7597750_7 Protein conserved in bacteria K06966,K07726,K09004,K13655 - 3.2.2.10 0.000000008349 65.0
EH2_k127_7624354_0 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 332.0
EH2_k127_7624354_1 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004067 225.0
EH2_k127_7624354_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000003992 157.0
EH2_k127_7624354_3 Uridine 5-monophosphate K13421 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016036,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896,GO:0051716,GO:0071496 2.4.2.10,4.1.1.23 0.000000000000000000000000002126 120.0
EH2_k127_7624354_4 Protein of unknown function (DUF3795) - - - 0.00000000000002646 78.0
EH2_k127_7624354_5 AAA domain K07028 - - 0.000000000008915 74.0
EH2_k127_7625494_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000009843 154.0
EH2_k127_7625494_1 TatD related DNase K03424 - - 0.0007 43.0
EH2_k127_7653124_0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 319.0
EH2_k127_7653124_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000001486 193.0
EH2_k127_7653124_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000005465 132.0
EH2_k127_7653124_3 ABC-type multidrug transport system, permease component K01992 - - 0.0000000001309 65.0
EH2_k127_7653124_4 ABC transporter, ATP-binding protein K01990 - - 0.00000002613 56.0
EH2_k127_7702916_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 608.0
EH2_k127_7702916_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 428.0
EH2_k127_7702916_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003922 273.0
EH2_k127_7710845_0 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
EH2_k127_7710845_1 RNA binding K07581 - - 0.000000000003485 72.0
EH2_k127_7710845_2 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.0000001295 57.0
EH2_k127_7710845_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0000001608 63.0
EH2_k127_7710845_4 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00006777 50.0
EH2_k127_7757980_0 metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 419.0
EH2_k127_7757980_1 zinc finger - - - 0.0000000000000000000000000000000000000000000000000000193 198.0
EH2_k127_7757980_10 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000002595 70.0
EH2_k127_7757980_11 Transcriptional regulator - - - 0.000004038 52.0
EH2_k127_7757980_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001066 143.0
EH2_k127_7757980_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.000000000000000000000000000002879 135.0
EH2_k127_7757980_4 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001168 118.0
EH2_k127_7757980_5 Pfam:DUF552 K09152 - - 0.000000000000000000000008838 105.0
EH2_k127_7757980_6 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000002595 95.0
EH2_k127_7757980_7 glycolate biosynthetic process K01091,K06019 - 3.1.3.18,3.6.1.1 0.00000000000000002212 90.0
EH2_k127_7757980_8 binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001737 77.0
EH2_k127_7757980_9 - - - - 0.0000000000003973 77.0
EH2_k127_7861586_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000005566 86.0
EH2_k127_7926209_0 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 GO:0001505,GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010033,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0017144,GO:0019676,GO:0019740,GO:0019752,GO:0030447,GO:0033993,GO:0036267,GO:0040007,GO:0042133,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070783,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071704,GO:0097054,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901700,GO:1901701 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 582.0
EH2_k127_7926209_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 378.0
EH2_k127_7926209_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 304.0
EH2_k127_7926209_3 PFAM metal-dependent phosphohydrolase, HD sub domain K17487 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.1.4.56 0.000000000000000000000000000000000000002351 155.0
EH2_k127_7926209_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000003538 120.0
EH2_k127_7926209_5 Zn-dependent proteases and their inactivated homologs K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000001134 58.0
EH2_k127_8001238_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000001268 107.0
EH2_k127_8021703_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 549.0
EH2_k127_8021703_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 520.0
EH2_k127_8021703_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
EH2_k127_8021703_3 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000007351 258.0
EH2_k127_8021703_4 Ser thr protein kinase K07176 - - 0.0000000000000000000000000000000000000000000000000002031 194.0
EH2_k127_8021703_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01923 - 5.4.99.18,6.3.2.6 0.00000000000000000000001812 102.0
EH2_k127_8021703_6 FMN binding K03809 - 1.6.5.2 0.000000000000005861 76.0
EH2_k127_8058185_0 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000001163 181.0
EH2_k127_8058185_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000001136 128.0
EH2_k127_8058185_2 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000005189 112.0
EH2_k127_8058185_3 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000006739 111.0
EH2_k127_8058185_4 thioesterase K07107 - - 0.00000000000000002775 88.0
EH2_k127_8058185_5 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000001469 74.0
EH2_k127_8058185_8 - - - - 0.00001608 50.0
EH2_k127_8058246_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.00000000000000000000000000000000009249 145.0
EH2_k127_8058246_1 PFAM Methyltransferase type 11 - - - 0.000000000008738 73.0
EH2_k127_8059008_0 COG0531 Amino acid transporters - - - 0.000000000000000000000000000000000000000000000000000000009768 216.0
EH2_k127_8059008_1 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000002212 176.0
EH2_k127_8081411_0 - - - - 0.0000000000000000000000000000000000000000000000000004012 197.0
EH2_k127_8081411_1 - - - - 0.00000000000002182 79.0
EH2_k127_8081411_2 COG1522 Transcriptional regulators K03718 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000008454 53.0
EH2_k127_8089628_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000001146 230.0
EH2_k127_8089628_1 FR47-like protein - - - 0.0000000000000000000000000000000000000000008407 160.0
EH2_k127_8089628_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000134 166.0
EH2_k127_8089628_4 copG family - - - 0.00000000000000000004888 95.0
EH2_k127_8089628_5 ABC-2 type transporter K01992 - - 0.0000000000000000001237 98.0
EH2_k127_8089628_6 PFAM beta-lactamase domain protein - - - 0.00000000000000003776 91.0
EH2_k127_8089628_7 Methyltransferase - - - 0.00000000007741 65.0
EH2_k127_8089628_8 Acetyltransferase (GNAT) domain - - - 0.00000003367 59.0
EH2_k127_8089628_9 - - - - 0.00000302 52.0
EH2_k127_8123910_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.00000000000000000000000000000000000000000000004853 183.0
EH2_k127_8123910_1 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000002605 120.0
EH2_k127_8123910_2 Domain of unknown function (DUF4443) - - - 0.00000000000000000000003491 108.0
EH2_k127_8140149_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009899 280.0
EH2_k127_8140149_1 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.00000000000000000008449 101.0
EH2_k127_8140149_2 dienelactone hydrolase - - - 0.00000008347 64.0
EH2_k127_8158430_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000001259 286.0
EH2_k127_8158430_1 - - - - 0.00001486 51.0
EH2_k127_8170440_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 406.0
EH2_k127_8170440_1 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000002763 157.0
EH2_k127_8170440_2 Belongs to the eukaryotic ribosomal protein eL34 family K02915 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000003141 78.0
EH2_k127_8170440_3 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000006247 53.0
EH2_k127_8170440_4 Integral membrane protein DUF106 - - - 0.000001909 56.0
EH2_k127_817854_0 DUF72 domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 317.0
EH2_k127_817854_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000001033 98.0
EH2_k127_817854_2 Protein of unknown function DUF72 - - - 0.0000000000000002538 90.0
EH2_k127_817854_3 peptidase - - - 0.0003134 46.0
EH2_k127_8209101_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 451.0
EH2_k127_8209101_1 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 392.0
EH2_k127_8209101_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000001039 198.0
EH2_k127_8209101_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000001966 147.0
EH2_k127_8209101_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000001866 116.0
EH2_k127_8209101_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000003466 96.0
EH2_k127_8209101_6 acetyltransferase K06976 - - 0.00001854 55.0
EH2_k127_8214566_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 303.0
EH2_k127_8214566_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001183 258.0
EH2_k127_8214566_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000003577 171.0
EH2_k127_8214566_3 PFAM glutaredoxin - - - 0.00000000000000004417 84.0
EH2_k127_8214566_4 CoA-binding protein K06929 - - 0.0000000000000005708 81.0
EH2_k127_8214566_5 Thioredoxin - - - 0.0000000000000007121 82.0
EH2_k127_8214566_6 PFAM CoA-binding domain protein K06929 - - 0.00000000000001568 75.0
EH2_k127_8214566_7 - - - - 0.000000000001688 75.0
EH2_k127_8214566_8 Mo-molybdopterin cofactor metabolic process K03753 - - 0.000001029 52.0
EH2_k127_835082_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 592.0
EH2_k127_835082_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 495.0
EH2_k127_847016_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 608.0
EH2_k127_847016_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 565.0
EH2_k127_847016_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000003153 245.0
EH2_k127_847016_11 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
EH2_k127_847016_12 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000001336 216.0
EH2_k127_847016_13 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000002607 153.0
EH2_k127_847016_14 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000008833 144.0
EH2_k127_847016_15 DEAD DEAH box helicase domain protein K10896 - - 0.000000000000000000000000000007123 128.0
EH2_k127_847016_16 Protein of unknown function (DUF521) K09123 - - 0.0008989 42.0
EH2_k127_847016_2 cysteine-tRNA ligase activity K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 472.0
EH2_k127_847016_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 472.0
EH2_k127_847016_4 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 418.0
EH2_k127_847016_5 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 345.0
EH2_k127_847016_6 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 316.0
EH2_k127_847016_7 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 295.0
EH2_k127_847016_8 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001167 276.0
EH2_k127_847016_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001782 263.0
EH2_k127_848729_0 PFAM hydrogenase formation HypD protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 375.0
EH2_k127_848729_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 366.0
EH2_k127_848729_10 Predicted membrane protein (DUF2085) - - - 0.00000000000001297 82.0
EH2_k127_848729_11 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000008049 69.0
EH2_k127_848729_12 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000003114 61.0
EH2_k127_848729_2 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
EH2_k127_848729_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000006566 184.0
EH2_k127_848729_4 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.00000000000000000000000000000000000000371 153.0
EH2_k127_848729_5 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002341 149.0
EH2_k127_848729_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000002384 149.0
EH2_k127_848729_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000001314 138.0
EH2_k127_848729_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000000000003176 102.0
EH2_k127_848729_9 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000001083 96.0
EH2_k127_860009_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 331.0
EH2_k127_860009_1 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000000000001495 136.0
EH2_k127_860009_2 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000005593 100.0
EH2_k127_860009_3 Amidohydrolase K07045 - - 0.0000000000000000001937 97.0
EH2_k127_892818_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007525 273.0
EH2_k127_892818_1 tRNA (Uracil-5-)-methyltransferase - - - 0.00000000000000000000000000000000000000000000000001804 187.0
EH2_k127_892818_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.000000000000000000001982 95.0
EH2_k127_892818_3 Protein of unknown function (DUF2798) - - - 0.0000138 49.0
EH2_k127_918409_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 572.0
EH2_k127_918409_1 Protein of unknown function (DUF3795) - - - 0.0000000191 60.0
EH2_k127_918409_2 - - - - 0.000003179 53.0