Overview

ID MAG01104
Name EH3_bin.45
Sample SMP0030
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order Methanomassiliicoccales
Family UBA472
Genus JAJRAN01
Species
Assembly information
Completeness (%) 70.42
Contamination (%) 1.99
GC content (%) 58.0
N50 (bp) 4,429
Genome size (bp) 1,303,904

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1404

Gene name Description KEGG GOs EC E-value Score Sequence
EH3_k127_1070684_0 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 339.0
EH3_k127_1070684_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000006644 191.0
EH3_k127_1070684_2 Protein of unknown function (DUF835) - - - 0.00000001499 64.0
EH3_k127_1109007_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.374e-301 942.0
EH3_k127_1109007_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 361.0
EH3_k127_1109007_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006604 278.0
EH3_k127_1109007_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000002618 103.0
EH3_k127_1157449_0 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000166 291.0
EH3_k127_1157449_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000002789 161.0
EH3_k127_1157449_2 carbohydrate binding K14965,K17495 - - 0.0000001722 66.0
EH3_k127_1160478_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05559,K14086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 389.0
EH3_k127_1160478_1 PFAM NADH-ubiquinone oxidoreductase chain 49kDa K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 344.0
EH3_k127_1160478_2 PFAM respiratory-chain NADH dehydrogenase subunit 1 K14087 - - 0.00000000000000000000000000000000000000000000000000000000000000707 229.0
EH3_k127_1160478_3 PFAM NADH ubiquinone oxidoreductase, 20 K14088 - - 0.0000000000000000000000000000000000000000000000001046 183.0
EH3_k127_1160478_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000002182 164.0
EH3_k127_1160478_5 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K14089 - - 0.0000001141 58.0
EH3_k127_1160478_6 glyoxalase III activity - - - 0.00002848 47.0
EH3_k127_1160478_7 4Fe-4S dicluster domain K00338,K14091 - 1.6.5.3 0.0001385 46.0
EH3_k127_1193337_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 367.0
EH3_k127_1193337_1 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000004794 206.0
EH3_k127_1193337_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000002033 192.0
EH3_k127_1193337_3 Heterodisulfide reductase subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000004727 98.0
EH3_k127_1205829_0 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005437 238.0
EH3_k127_1205829_1 - - - - 0.000000000000000000000000000000000000000000000000000000004834 205.0
EH3_k127_1205829_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000004069 154.0
EH3_k127_1205829_3 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000006385 96.0
EH3_k127_1208485_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000002534 189.0
EH3_k127_1208485_1 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000003253 130.0
EH3_k127_1210160_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 428.0
EH3_k127_1210160_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000001418 212.0
EH3_k127_1210160_2 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000556 180.0
EH3_k127_1210160_3 TIGRFAM adenylyl cyclase CyaB K05873 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 4.6.1.1 0.000000000000000000000000000000000003804 146.0
EH3_k127_1210160_4 CAAX protease self-immunity - - - 0.000000000000000000000000000001241 136.0
EH3_k127_1210160_5 RNA binding K09736 - - 0.000000000000000000001235 99.0
EH3_k127_1210160_6 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000000000006703 86.0
EH3_k127_1218398_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000003142 256.0
EH3_k127_1218398_1 - - - - 0.000000000000195 78.0
EH3_k127_1219369_0 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 468.0
EH3_k127_1219369_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 286.0
EH3_k127_1219369_2 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000001605 212.0
EH3_k127_1219369_3 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000002594 125.0
EH3_k127_1219369_4 Conserved repeat domain - - - 0.00000000000000002026 96.0
EH3_k127_1235292_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 376.0
EH3_k127_1235292_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001636 249.0
EH3_k127_1249849_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 520.0
EH3_k127_1249849_1 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000000003213 155.0
EH3_k127_1249849_2 4Fe-4S single cluster domain - - - 0.00000000000000000000002641 103.0
EH3_k127_1249849_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000004041 87.0
EH3_k127_1253393_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 579.0
EH3_k127_1253393_1 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 322.0
EH3_k127_1253393_2 transcriptional - - - 0.00000000000000000000000000000001506 135.0
EH3_k127_1258160_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 551.0
EH3_k127_1258160_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 349.0
EH3_k127_1258160_2 - - - - 0.000000000000000000000000000000000000000000000000000001153 201.0
EH3_k127_1258160_3 LysE type translocator - - - 0.000000000000000000000000000000000003386 145.0
EH3_k127_1258160_4 - - - - 0.000000000000000000000003547 117.0
EH3_k127_1258160_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000000001406 93.0
EH3_k127_1258160_6 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000002326 90.0
EH3_k127_1258160_7 Endodeoxyribonuclease RusA - - - 0.00000000000001822 79.0
EH3_k127_1258160_8 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.11,1.2.7.3 0.000000004107 57.0
EH3_k127_1258160_9 electron transfer activity K05337 - - 0.000002543 54.0
EH3_k127_1260510_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 395.0
EH3_k127_1260510_1 RibD C-terminal domain K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000729 200.0
EH3_k127_1260510_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000003257 169.0
EH3_k127_1260510_3 SCP-2 sterol transfer family - - - 0.00000000000000001218 88.0
EH3_k127_1302991_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 539.0
EH3_k127_1302991_1 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000008172 192.0
EH3_k127_1302991_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000889 192.0
EH3_k127_1302991_3 Domain of unknown function (DUF4443) - - - 0.000000000000000000000000000000000000000000001041 171.0
EH3_k127_1302991_4 - - - - 0.000000000000000000000000000000000758 132.0
EH3_k127_1324486_0 COGs COG0145 N-methylhydantoinase A acetone carboxylase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 374.0
EH3_k127_1324486_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
EH3_k127_1324486_2 V4R K07013 - - 0.000000000000000000000000000000000000000000002428 174.0
EH3_k127_1324486_3 - - - - 0.0000000000002075 74.0
EH3_k127_1325899_0 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000006016 134.0
EH3_k127_1325899_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000004368 124.0
EH3_k127_1325899_2 transcription regulator activity - - - 0.0000000000000004076 86.0
EH3_k127_1363789_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000007915 154.0
EH3_k127_1363789_1 PFAM PEGA domain - - - 0.000000000000000000000000000002457 136.0
EH3_k127_1363789_2 PFAM SOUL heme-binding protein - - - 0.00000004088 55.0
EH3_k127_1363789_3 COG3291 FOG PKD repeat K01387 GO:0005575,GO:0005576 3.4.24.3 0.0008715 51.0
EH3_k127_1399819_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001057 276.0
EH3_k127_1399819_1 PFAM BioY K03523 - - 0.0000000000000000000003655 104.0
EH3_k127_1453086_0 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008781 262.0
EH3_k127_1453086_1 von Willebrand factor (vWF) type A domain - - - 0.0000000004647 70.0
EH3_k127_1453086_2 Trehalose utilisation - - - 0.000005548 51.0
EH3_k127_1462039_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 7.356e-207 660.0
EH3_k127_1521581_0 Domain of unknown function DUF87 K06915,K19172 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 507.0
EH3_k127_1521581_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 313.0
EH3_k127_1521581_2 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000003019 245.0
EH3_k127_1521581_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000001976 106.0
EH3_k127_1591699_0 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000009077 66.0
EH3_k127_1591699_1 Peptidase m28 - - - 0.000000001377 71.0
EH3_k127_1617511_0 Sulfatase K01130 - 3.1.6.1 1.782e-270 838.0
EH3_k127_1617511_1 Methanogenesis marker 16 metalloprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 379.0
EH3_k127_1617511_2 GMP synthase C terminal domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 328.0
EH3_k127_169261_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 489.0
EH3_k127_169261_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 407.0
EH3_k127_169261_10 - - - - 0.00008974 52.0
EH3_k127_169261_11 Protein of unknown function (DUF1847) - - - 0.0002902 47.0
EH3_k127_169261_2 Aminotransferase class-III K00821,K05830 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 399.0
EH3_k127_169261_3 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 364.0
EH3_k127_169261_4 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145,K05829 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 358.0
EH3_k127_169261_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 286.0
EH3_k127_169261_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 286.0
EH3_k127_169261_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000001798 228.0
EH3_k127_169261_8 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000002553 211.0
EH3_k127_169261_9 - - - - 0.000006082 55.0
EH3_k127_1710085_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 349.0
EH3_k127_1710085_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 339.0
EH3_k127_1710085_2 Uroporphyrinogen decarboxylase K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 296.0
EH3_k127_1710085_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000006269 211.0
EH3_k127_1710085_4 Methionine synthase B12-binding module cap domain protein K16179 - - 0.0000000000000000000000000000000000000000000000000000000479 201.0
EH3_k127_1710085_5 Amidohydrolase K07045 - - 0.0000000000000000000000000001767 126.0
EH3_k127_1710085_6 4Fe-4S dicluster domain - - - 0.00000000000000000000002607 102.0
EH3_k127_1710085_7 toxin-antitoxin pair type II binding - - - 0.00000000000000000000004299 102.0
EH3_k127_1710085_8 helix_turn_helix ASNC type - - - 0.00000007905 63.0
EH3_k127_1710085_9 membrane - - - 0.0001942 49.0
EH3_k127_1723328_0 RDD family - - - 0.00000002794 61.0
EH3_k127_1723328_1 protein conserved in archaea - - - 0.000135 51.0
EH3_k127_1744025_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 407.0
EH3_k127_1744025_1 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006053 246.0
EH3_k127_1744025_2 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000000000000000000284 192.0
EH3_k127_1744025_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000569 94.0
EH3_k127_1744025_4 transcriptional regulators - - - 0.000000000000001953 83.0
EH3_k127_1744025_5 Transcriptional regulators - - - 0.00005834 50.0
EH3_k127_1774562_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000329 213.0
EH3_k127_1774562_1 KaiC K07331 - - 0.000000000000000000000000000000000000000000000002845 181.0
EH3_k127_1774562_2 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000005805 81.0
EH3_k127_1774562_3 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000002297 71.0
EH3_k127_1774562_4 - - - - 0.00000008343 59.0
EH3_k127_1774562_5 SPFH domain-Band 7 family - - - 0.00002984 52.0
EH3_k127_1796847_0 Toprim domain K02316 - - 0.00000000000000000000000000000000000000000000001102 172.0
EH3_k127_1796847_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000003632 136.0
EH3_k127_1796847_2 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00006841 50.0
EH3_k127_1796847_3 Belongs to the ompA family K20276 - - 0.00008138 53.0
EH3_k127_1906144_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 346.0
EH3_k127_1906144_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 290.0
EH3_k127_1906144_2 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000002327 178.0
EH3_k127_1956442_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 423.0
EH3_k127_1956442_1 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 417.0
EH3_k127_1956442_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000116 129.0
EH3_k127_1956442_3 - - - - 0.0000000000000000000000002977 107.0
EH3_k127_1956442_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000003614 98.0
EH3_k127_1985990_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 339.0
EH3_k127_1985990_1 PFAM GvpD gas vesicle - - - 0.000000000000000000001216 109.0
EH3_k127_1985990_2 Thioredoxin-like domain K03671 - - 0.0000000000000001041 86.0
EH3_k127_201045_0 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 341.0
EH3_k127_201045_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001415 143.0
EH3_k127_201045_2 - - - - 0.00000000000000000000009116 101.0
EH3_k127_2029396_0 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 344.0
EH3_k127_2029396_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000002051 238.0
EH3_k127_2029396_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000002111 233.0
EH3_k127_2029396_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000003476 166.0
EH3_k127_2052228_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 423.0
EH3_k127_2052228_1 PFAM CBS domain - - - 0.0000000000000000000006756 101.0
EH3_k127_2063613_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 5.475e-212 677.0
EH3_k127_2063613_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 506.0
EH3_k127_2063613_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 264.0
EH3_k127_2063613_3 TIGRFAM Riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000004269 229.0
EH3_k127_2063613_4 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000006035 215.0
EH3_k127_2063613_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000004171 186.0
EH3_k127_2063613_6 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000000000000001005 173.0
EH3_k127_2063613_7 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000007552 59.0
EH3_k127_2068481_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 600.0
EH3_k127_2068481_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 387.0
EH3_k127_2068481_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 326.0
EH3_k127_2068481_3 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002763 246.0
EH3_k127_2068481_4 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000002548 148.0
EH3_k127_2068481_5 - - - - 0.00008544 47.0
EH3_k127_2099509_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 334.0
EH3_k127_2099509_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 331.0
EH3_k127_2099509_2 PFAM Polysaccharide pyruvyl transferase K16563 - - 0.00000000000000000000000000000000000000000000005077 180.0
EH3_k127_2099509_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000003562 139.0
EH3_k127_2102647_0 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000001169 218.0
EH3_k127_2102647_1 Abc transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000004011 205.0
EH3_k127_2102647_2 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000837 93.0
EH3_k127_2139355_0 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 389.0
EH3_k127_2139355_1 Belongs to the Fur family K09825 - - 0.000000000000000000008616 96.0
EH3_k127_2153454_0 KH domain K07041 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 427.0
EH3_k127_2153454_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 395.0
EH3_k127_2153454_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 373.0
EH3_k127_2153454_3 Putative Phosphatase - - - 0.0000000000000000000004519 106.0
EH3_k127_2167481_0 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000001008 175.0
EH3_k127_2167481_1 COG1668 ABC-type Na efflux pump, permease component - - - 0.00000000000000000000000000000000003644 150.0
EH3_k127_2167481_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000007325 110.0
EH3_k127_2170389_0 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000001455 203.0
EH3_k127_2170389_1 EamA-like transporter family - - - 0.00000000000000000000000000729 121.0
EH3_k127_2170389_2 PFAM Amino acid-binding ACT - - - 0.00000000000001337 79.0
EH3_k127_2204821_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 316.0
EH3_k127_2204821_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000001043 138.0
EH3_k127_2204821_2 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000002998 134.0
EH3_k127_2204821_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000002052 138.0
EH3_k127_2204821_4 TIGRFAM C_GCAxxG_C_C family - - - 0.000000000000000001656 90.0
EH3_k127_2204821_5 - K00960 - 2.7.7.6 0.000000000000000002635 85.0
EH3_k127_2204821_6 PAS domain K02488 - 2.7.7.65 0.00000000000001252 86.0
EH3_k127_2204821_7 Belongs to the FPP GGPP synthase family K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000007954 73.0
EH3_k127_2204821_8 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0004357 50.0
EH3_k127_2237455_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000374 242.0
EH3_k127_2237455_1 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000002097 179.0
EH3_k127_2237455_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000001619 182.0
EH3_k127_2237455_3 TonB-linked outer membrane protein, SusC RagA family - - - 0.00001147 57.0
EH3_k127_2246469_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 296.0
EH3_k127_2246469_1 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000001674 245.0
EH3_k127_2246469_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000005425 219.0
EH3_k127_2246469_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000006411 226.0
EH3_k127_2246469_4 Peptidase family M50 - - - 0.00000000000007597 76.0
EH3_k127_2246469_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000001851 61.0
EH3_k127_2246469_6 - - - - 0.000001448 60.0
EH3_k127_2292674_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000009982 275.0
EH3_k127_2292674_1 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000008522 211.0
EH3_k127_2292674_2 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.000000000000003016 79.0
EH3_k127_2292674_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000006545 70.0
EH3_k127_2323912_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001348 263.0
EH3_k127_2323912_1 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000007084 136.0
EH3_k127_2323912_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000003082 83.0
EH3_k127_2371848_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000001112 176.0
EH3_k127_2371848_1 Double zinc ribbon - - - 0.00000000000000000000000000000000000001375 156.0
EH3_k127_2371848_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.0000000000000000000000001635 111.0
EH3_k127_2381511_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 293.0
EH3_k127_2381511_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000347 132.0
EH3_k127_2381511_2 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000006026 75.0
EH3_k127_2397891_0 aminotransferase - - - 0.0000000000000000000000000000000005217 148.0
EH3_k127_2397891_1 Flavin reductase-like protein - - - 0.000000000000000197 86.0
EH3_k127_2414057_0 PFAM Phenylalanine and histidine ammonia-lyase K01745,K10775 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 4.3.1.24,4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 482.0
EH3_k127_2414057_1 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 318.0
EH3_k127_2414057_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000002743 167.0
EH3_k127_2426407_0 Glycosyltransferase like family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001695 282.0
EH3_k127_2426407_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000173 153.0
EH3_k127_2426407_2 Nucleotidyl transferase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000001263 108.0
EH3_k127_2426407_3 PFAM amino acid-binding ACT domain protein - - - 0.00007283 48.0
EH3_k127_2430054_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 608.0
EH3_k127_2430054_1 methanogenesis marker protein 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 345.0
EH3_k127_2430054_2 Belongs to the UPF0288 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 311.0
EH3_k127_2430054_3 Methanogenesis marker protein 5 - - - 0.0000000000000000000000000000000000000000000000000000000000001275 214.0
EH3_k127_2430054_4 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000001688 149.0
EH3_k127_2430054_5 TIGRFAM methanogenesis marker protein 6 - - - 0.000000000000000000000000000000005637 132.0
EH3_k127_2430054_6 Belongs to the SfsA family K06206 - - 0.00000000000000000000000004279 112.0
EH3_k127_2430054_7 Protein of unknown function (DUF3795) - - - 0.0005723 46.0
EH3_k127_2466518_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000001442 184.0
EH3_k127_2466518_2 - - - - 0.0000000002435 70.0
EH3_k127_2466518_3 - - - - 0.00003737 50.0
EH3_k127_2468316_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000003662 221.0
EH3_k127_2468316_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000002048 220.0
EH3_k127_2468316_2 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000006392 167.0
EH3_k127_2498180_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 360.0
EH3_k127_2498180_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000005546 150.0
EH3_k127_2498180_2 - - - - 0.0000000000000001283 89.0
EH3_k127_2498180_3 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000007754 62.0
EH3_k127_2502932_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 587.0
EH3_k127_2502932_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000003145 121.0
EH3_k127_2522035_0 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000002849 138.0
EH3_k127_2522035_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000002309 93.0
EH3_k127_2522035_2 OmpA family - - - 0.0000001491 64.0
EH3_k127_2536013_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000003166 153.0
EH3_k127_2536013_1 Membrane - - - 0.000000000000000000000000000001825 130.0
EH3_k127_2536013_2 response regulator K10943 - - 0.000267 45.0
EH3_k127_2557538_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 377.0
EH3_k127_2557538_1 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000004734 220.0
EH3_k127_2557538_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000001337 117.0
EH3_k127_2557538_3 Putative zinc- or iron-chelating domain - - - 0.000000009078 57.0
EH3_k127_2560223_0 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 321.0
EH3_k127_2560223_1 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000001173 129.0
EH3_k127_2568129_0 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000001043 227.0
EH3_k127_2568129_1 Adenosylcobinamide amidohydrolase - - - 0.00000000000001253 83.0
EH3_k127_2611031_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 601.0
EH3_k127_2611031_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000205 267.0
EH3_k127_2611031_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000001852 215.0
EH3_k127_2645027_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 415.0
EH3_k127_2645027_1 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000002959 138.0
EH3_k127_2645027_2 - - - - 0.0000000000000000008456 100.0
EH3_k127_2645027_3 - - - - 0.0002545 51.0
EH3_k127_2660185_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000003327 140.0
EH3_k127_2660185_1 Protein of unknown function (DUF835) - - - 0.0000001741 62.0
EH3_k127_2676959_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009229 266.0
EH3_k127_2676959_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000134 243.0
EH3_k127_2676959_2 Membrane K09790 - - 0.000000000000000000000002836 106.0
EH3_k127_2676959_4 - - - - 0.00000000000003167 85.0
EH3_k127_2677924_0 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 293.0
EH3_k127_2677924_1 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000002201 112.0
EH3_k127_2677924_2 - - - - 0.000000005237 67.0
EH3_k127_2677924_3 PFAM Uncharacterised protein family UPF0047 - - - 0.00005131 46.0
EH3_k127_2693805_0 Hydantoinaseoxoprolinase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 395.0
EH3_k127_2693805_1 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000000000000000000002265 223.0
EH3_k127_2693805_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000003631 194.0
EH3_k127_2693805_3 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000001613 186.0
EH3_k127_2693805_4 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0001561 44.0
EH3_k127_2710399_0 HMGL-like K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 517.0
EH3_k127_2710399_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 319.0
EH3_k127_2727289_0 Domain of unknown function (DUF4172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 308.0
EH3_k127_2727289_1 Thioredoxin reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 291.0
EH3_k127_2727289_2 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000004275 199.0
EH3_k127_2727289_3 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000003584 163.0
EH3_k127_2727289_4 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000001589 159.0
EH3_k127_2727289_5 PRC-barrel domain - - - 0.000000000000000000006799 94.0
EH3_k127_2727289_6 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000001582 59.0
EH3_k127_2749106_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 610.0
EH3_k127_2749106_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 334.0
EH3_k127_2782935_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 296.0
EH3_k127_2782935_1 Flavodoxin - - - 0.0000009846 57.0
EH3_k127_2806883_0 arsenite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 407.0
EH3_k127_2806883_1 PQ loop repeat K15383 - - 0.000000000000000000002412 96.0
EH3_k127_2899866_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 450.0
EH3_k127_2899866_1 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337,K22163 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 315.0
EH3_k127_2899866_2 Belongs to the complex I 20 kDa subunit family K00331,K22159 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002803 279.0
EH3_k127_2899866_3 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000004299 195.0
EH3_k127_2899866_4 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000001347 143.0
EH3_k127_2899866_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000001275 125.0
EH3_k127_2899866_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000003749 65.0
EH3_k127_2949699_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 353.0
EH3_k127_2949699_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000009941 244.0
EH3_k127_2949699_2 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000000001577 214.0
EH3_k127_2949699_3 amino acid-binding ACT domain protein - - - 0.000000000000002515 83.0
EH3_k127_2958253_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 501.0
EH3_k127_2958253_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 464.0
EH3_k127_2958253_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 397.0
EH3_k127_2958253_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 391.0
EH3_k127_2958253_4 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 352.0
EH3_k127_2958253_5 prephenate dehydrogenase K04517,K14170,K14187 - 1.3.1.12,4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000004911 244.0
EH3_k127_2958253_6 shikimate kinase activity K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000004942 241.0
EH3_k127_2958253_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000007852 222.0
EH3_k127_2958253_8 NIL - - - 0.000000000000000000000000000005003 124.0
EH3_k127_2958253_9 Belongs to the UPF0280 family K09740 - - 0.0000003269 53.0
EH3_k127_2965356_0 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003336 282.0
EH3_k127_2965356_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001453 282.0
EH3_k127_2965356_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001607 242.0
EH3_k127_2965356_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000002576 169.0
EH3_k127_3007246_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 352.0
EH3_k127_3007246_1 Methyltransferase type 11 - - - 0.000000000000000000000000000001566 128.0
EH3_k127_3007246_2 transcriptional regulator - - - 0.000000000000000000000474 108.0
EH3_k127_3007246_3 Carboxymuconolactone decarboxylase family - - - 0.000000000000000003736 89.0
EH3_k127_3020472_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 572.0
EH3_k127_3020472_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 524.0
EH3_k127_3020472_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000006462 207.0
EH3_k127_3020472_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000002575 101.0
EH3_k127_3068228_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 447.0
EH3_k127_3068228_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 334.0
EH3_k127_307813_0 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000001167 252.0
EH3_k127_307813_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000006409 242.0
EH3_k127_307813_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000005634 229.0
EH3_k127_307813_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000001803 168.0
EH3_k127_307813_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000007664 123.0
EH3_k127_3111031_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 549.0
EH3_k127_3111031_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000007084 191.0
EH3_k127_3116639_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 551.0
EH3_k127_3116639_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 326.0
EH3_k127_3116639_2 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000003827 152.0
EH3_k127_3150141_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 343.0
EH3_k127_3150141_1 nitrogen fixation - - - 0.0000000000000000004468 92.0
EH3_k127_3150141_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000369 67.0
EH3_k127_3198915_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 517.0
EH3_k127_3198915_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008876 242.0
EH3_k127_3198915_2 deoxyribonuclease I activity K06131,K06915 - - 0.0000000000000000001662 98.0
EH3_k127_3198915_3 electron transfer activity K05337 - - 0.000001117 52.0
EH3_k127_3200571_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 403.0
EH3_k127_3200571_1 B12 binding domain - - - 0.00000000000000000000000000000000000002414 153.0
EH3_k127_3210887_0 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000001884 221.0
EH3_k127_3210887_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000002717 115.0
EH3_k127_3248022_0 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003648 283.0
EH3_k127_3248022_1 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000003093 122.0
EH3_k127_3248022_2 LemA family K03744 - - 0.0000000000000000000000009852 112.0
EH3_k127_3248022_3 prohibitin homologues - - - 0.0000000000000003262 81.0
EH3_k127_3248022_4 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000001686 85.0
EH3_k127_3248022_5 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00003746 53.0
EH3_k127_3249949_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000002482 196.0
EH3_k127_3249949_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.00000000000000001822 86.0
EH3_k127_3249949_2 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000113 68.0
EH3_k127_3262769_0 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000003284 118.0
EH3_k127_3262769_1 - - - - 0.00000000000000003571 89.0
EH3_k127_3262769_2 COG1748 Saccharopine dehydrogenase and related K00290 - 1.5.1.7 0.000000004458 61.0
EH3_k127_3284446_0 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 308.0
EH3_k127_3287328_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974,K18105 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4,6.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000001384 251.0
EH3_k127_3287328_1 PAC2 family K06869 - - 0.00000000000000000000007244 104.0
EH3_k127_330717_0 PFAM ABC transporter related K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 359.0
EH3_k127_330717_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 335.0
EH3_k127_330717_2 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000000000000000000000000000000000000004093 210.0
EH3_k127_330717_3 PFAM ABC-2 type transporter K09694 - - 0.0000000000009024 79.0
EH3_k127_3340073_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 380.0
EH3_k127_3340073_1 pfam abc K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002213 257.0
EH3_k127_3340073_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000008741 218.0
EH3_k127_3340073_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000001342 125.0
EH3_k127_3340073_4 LmbE family - - - 0.000000000000000000005073 103.0
EH3_k127_3349692_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 293.0
EH3_k127_3349692_1 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000003073 221.0
EH3_k127_3349692_2 homolog of PrgY (pheromone shutdown protein) - - - 0.0000000000000000000000000000000000001101 150.0
EH3_k127_3349692_3 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000004059 85.0
EH3_k127_3380119_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 491.0
EH3_k127_3380119_1 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 394.0
EH3_k127_3380119_2 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000009877 184.0
EH3_k127_3434224_0 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 286.0
EH3_k127_3434224_1 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000003653 227.0
EH3_k127_3434224_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000003568 200.0
EH3_k127_3434224_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000006248 82.0
EH3_k127_3434276_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 455.0
EH3_k127_3434276_1 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 368.0
EH3_k127_3434276_2 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 332.0
EH3_k127_3434276_3 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 294.0
EH3_k127_3434276_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000007538 221.0
EH3_k127_3434276_5 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000004662 164.0
EH3_k127_3434276_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000187 131.0
EH3_k127_3434276_7 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000001318 110.0
EH3_k127_3480307_0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000004528 239.0
EH3_k127_3480307_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000004018 221.0
EH3_k127_3480307_2 Protein of unknown function (DUF359) K09735 - - 0.000000000000000000003433 100.0
EH3_k127_3480307_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000001154 95.0
EH3_k127_3480307_4 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000006474 81.0
EH3_k127_3490345_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 476.0
EH3_k127_3490345_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 436.0
EH3_k127_3490345_10 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000000000000000000003119 200.0
EH3_k127_3490345_11 - - - - 0.00000000000002643 75.0
EH3_k127_3490345_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000384 58.0
EH3_k127_3490345_2 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 421.0
EH3_k127_3490345_3 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 387.0
EH3_k127_3490345_4 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 392.0
EH3_k127_3490345_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 313.0
EH3_k127_3490345_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
EH3_k127_3490345_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000009573 237.0
EH3_k127_3490345_8 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
EH3_k127_3490345_9 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000001482 209.0
EH3_k127_3511256_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 526.0
EH3_k127_3511256_1 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004525 281.0
EH3_k127_3511256_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 259.0
EH3_k127_3511256_3 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 256.0
EH3_k127_3511256_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000368 86.0
EH3_k127_3542864_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004346 275.0
EH3_k127_3542864_1 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006439 278.0
EH3_k127_3542864_2 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006804 247.0
EH3_k127_3542864_3 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 0.00006711 46.0
EH3_k127_3549801_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 317.0
EH3_k127_3549801_1 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005168 250.0
EH3_k127_3549801_2 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000005945 243.0
EH3_k127_3549801_3 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000005888 134.0
EH3_k127_3549801_4 PIN domain of ribonuclease K07060 GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904 - 0.0000000000000000000000000000003922 127.0
EH3_k127_3574741_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
EH3_k127_3574741_1 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.00000000000000000000000000000000000000000007301 164.0
EH3_k127_3574741_2 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.00000000000006646 73.0
EH3_k127_3574741_3 - - - - 0.00000001061 59.0
EH3_k127_3618434_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 347.0
EH3_k127_3618434_1 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000003488 181.0
EH3_k127_3618434_2 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000126 147.0
EH3_k127_3618434_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001586 151.0
EH3_k127_3618434_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000245 112.0
EH3_k127_3628323_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 408.0
EH3_k127_3628323_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000002978 109.0
EH3_k127_3645426_0 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000007665 151.0
EH3_k127_3645426_1 Membrane K09790 - - 0.0000000000000000000000005491 108.0
EH3_k127_3645426_2 protein conserved in archaea - - - 0.000000000000000000000002013 107.0
EH3_k127_3645426_3 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000007473 111.0
EH3_k127_3645426_4 - - - - 0.0000000000000000003199 90.0
EH3_k127_3653047_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 464.0
EH3_k127_3653047_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 282.0
EH3_k127_3669311_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 568.0
EH3_k127_3669311_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000002703 97.0
EH3_k127_3675621_0 Hydantoinase/oxoprolinase N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 595.0
EH3_k127_3675621_1 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 291.0
EH3_k127_3675621_2 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009558 256.0
EH3_k127_3675621_3 Formyl transferase - - - 0.000000000000000000000000000000000007609 147.0
EH3_k127_3675621_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000004695 67.0
EH3_k127_368541_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 339.0
EH3_k127_368541_1 - K00960 - 2.7.7.6 0.0000000000000000001297 89.0
EH3_k127_3689223_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 6.822e-196 625.0
EH3_k127_3689223_1 GrpB protein - - - 0.000000000000000000000000000000000000009872 151.0
EH3_k127_3689223_2 Coenzyme F390 synthetase - - - 0.00000000000000000005235 92.0
EH3_k127_3689223_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000003618 65.0
EH3_k127_3689223_4 lactoylglutathione lyase activity - - - 0.000003411 54.0
EH3_k127_3699491_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 417.0
EH3_k127_3699491_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003791 269.0
EH3_k127_3699491_2 PFAM TfuA domain protein, core - - - 0.0000000000000000000000000000000000000000000001135 176.0
EH3_k127_3699491_3 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.0000000000000000000000000000000001971 135.0
EH3_k127_3699491_4 helix_turn_helix ASNC type - - - 0.0000000000009798 74.0
EH3_k127_3699491_5 Tetrahydromethanopterin S-methyltransferase, subunit A K00577 - 2.1.1.86 0.000006373 49.0
EH3_k127_3709592_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 404.0
EH3_k127_3709592_1 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006931 266.0
EH3_k127_3709592_2 ATPases associated with a variety of cellular activities K09691 - - 0.000000000000000000000000000000000000000000000000001037 186.0
EH3_k127_3709592_3 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000000000003525 153.0
EH3_k127_3709592_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000003826 146.0
EH3_k127_3709592_5 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.000000000006427 73.0
EH3_k127_3714375_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 452.0
EH3_k127_3714375_1 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 312.0
EH3_k127_3714375_2 - - - - 0.000000000000000008646 87.0
EH3_k127_3813732_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000006998 260.0
EH3_k127_3813732_1 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00001321 49.0
EH3_k127_3814321_0 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 503.0
EH3_k127_3814321_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000009132 224.0
EH3_k127_3814321_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000001926 218.0
EH3_k127_3814321_3 - - - - 0.0000000000000000008594 89.0
EH3_k127_3814321_4 Protein of unknown function (DUF2769) - - - 0.0000001658 55.0
EH3_k127_3844228_0 COG0471 Di- and tricarboxylate transporters K14445 - - 0.00000000000000000000000000000000000000000000000000000000001403 224.0
EH3_k127_3848648_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000005095 192.0
EH3_k127_3848648_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000001226 183.0
EH3_k127_3848648_2 parallel beta-helix repeat K03671 - - 0.0000002234 63.0
EH3_k127_384953_0 Lamin Tail Domain - - - 0.0000000000000000000000000000000000000000000000000000000122 224.0
EH3_k127_384953_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000001124 109.0
EH3_k127_384953_2 Small-conductance mechanosensitive channel - - - 0.0001992 53.0
EH3_k127_38893_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001613 269.0
EH3_k127_38893_1 ABC-2 family transporter protein K01992 - - 0.000000000000005585 84.0
EH3_k127_3904751_0 Type II/IV secretion system protein K07332 - - 7.938e-220 696.0
EH3_k127_3904751_1 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 381.0
EH3_k127_3904751_2 toxin activity - - - 0.000000000000000000000001465 115.0
EH3_k127_3904751_3 - - - - 0.000000000000000000000003245 108.0
EH3_k127_3904751_4 - - - - 0.000004929 52.0
EH3_k127_3907099_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 456.0
EH3_k127_3907099_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 453.0
EH3_k127_3907099_2 Carbamoyl-phosphate synthase L chain, ATP binding domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 432.0
EH3_k127_3907099_3 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 344.0
EH3_k127_3907099_4 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000005661 257.0
EH3_k127_3907099_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000001712 241.0
EH3_k127_3907099_6 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000004873 149.0
EH3_k127_3907099_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000005475 111.0
EH3_k127_3907099_8 - - - - 0.0000000000000000005094 93.0
EH3_k127_3918060_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 351.0
EH3_k127_3918060_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000404 135.0
EH3_k127_3929777_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 613.0
EH3_k127_3929777_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 313.0
EH3_k127_3929777_2 Major intrinsic protein - - - 0.0000000000000000000000000000000000000897 151.0
EH3_k127_3929777_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000003592 136.0
EH3_k127_3948393_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 621.0
EH3_k127_3948393_1 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 372.0
EH3_k127_3948393_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 357.0
EH3_k127_3948393_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000002802 225.0
EH3_k127_3948393_4 COG1520 FOG WD40-like repeat - - - 0.00000000000000005544 93.0
EH3_k127_3948393_5 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000001044 67.0
EH3_k127_3948393_6 Protein of unknown function (DUF2797) - - - 0.0003606 51.0
EH3_k127_3966505_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000008516 177.0
EH3_k127_3966505_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00006916 51.0
EH3_k127_4010911_0 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000000006039 117.0
EH3_k127_4010911_1 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000005006 105.0
EH3_k127_4010911_2 - - - - 0.00000000000000000362 84.0
EH3_k127_4010911_3 FR47-like protein - - - 0.000000000004557 69.0
EH3_k127_4030264_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 333.0
EH3_k127_4030264_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000007982 175.0
EH3_k127_4030264_2 Transcriptional regulator PadR-like family - - - 0.0000000000007279 76.0
EH3_k127_4032106_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 462.0
EH3_k127_4032106_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.00000000000000000000001502 102.0
EH3_k127_4035468_0 PFAM Radical SAM K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 325.0
EH3_k127_4035468_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000008466 137.0
EH3_k127_4035468_2 PFAM Radical SAM K06937 - - 0.000000000000000000002627 95.0
EH3_k127_4035468_3 - - - - 0.00000000000000004746 84.0
EH3_k127_4038343_0 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003995 271.0
EH3_k127_4038343_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000002162 204.0
EH3_k127_4038343_2 Transcriptional regulator K07722 - - 0.000000000000000002809 87.0
EH3_k127_4038343_3 - - - - 0.0000000002149 65.0
EH3_k127_4038343_4 but it may be involved in stabilization of the trimeric complex - - - 0.000000001167 65.0
EH3_k127_4076329_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 613.0
EH3_k127_4076329_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 477.0
EH3_k127_4076329_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K18816 - 2.3.1.82 0.000000000000000000000000000000000000000001731 161.0
EH3_k127_4076329_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000004263 100.0
EH3_k127_4082863_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 486.0
EH3_k127_4082863_1 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000009751 171.0
EH3_k127_4082863_2 membrane - - - 0.000000000000000000000001562 111.0
EH3_k127_4082863_3 Phosphate transport regulator K07220 - - 0.00000000000000002226 86.0
EH3_k127_4095959_0 TrkA-C domain protein - - - 0.00000000000000000000000000000000000000000000000000000009763 202.0
EH3_k127_4095959_1 PhoU domain - - - 0.00000000000000000000000000000000000000000000000005677 184.0
EH3_k127_4096226_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 576.0
EH3_k127_4096226_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004505 273.0
EH3_k127_4096226_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000002316 220.0
EH3_k127_4096226_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000001817 196.0
EH3_k127_4096226_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000002625 140.0
EH3_k127_4096226_5 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000002349 91.0
EH3_k127_4096226_6 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000111 87.0
EH3_k127_4096226_7 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000002662 72.0
EH3_k127_4104942_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 390.0
EH3_k127_4104942_1 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000021 129.0
EH3_k127_4104942_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000003573 118.0
EH3_k127_41347_0 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 570.0
EH3_k127_41347_1 PFAM Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 411.0
EH3_k127_41347_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000461 209.0
EH3_k127_41347_3 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000000000000000003114 194.0
EH3_k127_41347_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000000000000000008712 188.0
EH3_k127_41347_5 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000006551 117.0
EH3_k127_41347_6 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000007258 121.0
EH3_k127_41347_7 - - - - 0.0000000000000000000000003718 108.0
EH3_k127_41347_8 - - - - 0.0000000000000000002129 90.0
EH3_k127_41347_9 AsnC family K03719 - - 0.00000000000007685 77.0
EH3_k127_4143537_0 helicase superfamily c-terminal domain K10896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 456.0
EH3_k127_4143537_1 Iron-sulfur cluster assembly accessory protein K13628,K15724 - - 0.00000000000000000000000000000000386 130.0
EH3_k127_4143537_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000002557 82.0
EH3_k127_4146052_0 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 360.0
EH3_k127_4146052_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 332.0
EH3_k127_4146052_2 DNA polymerase alpha chain like domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
EH3_k127_4146052_3 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
EH3_k127_4146052_4 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000008549 231.0
EH3_k127_4160297_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 353.0
EH3_k127_4160297_1 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000002193 211.0
EH3_k127_4160297_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000007831 134.0
EH3_k127_4160297_3 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000188 137.0
EH3_k127_4160297_4 protein conserved in archaea - - - 0.0000000000000000000000000004672 119.0
EH3_k127_4160297_5 Glycosyl transferase family 21 K22278 - 3.5.1.104 0.0000000000007022 78.0
EH3_k127_4160297_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000004396 68.0
EH3_k127_4160297_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000001518 61.0
EH3_k127_416343_0 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 522.0
EH3_k127_416343_1 PFAM Radical SAM superfamily - - - 0.00000000000000000000000000000000000007981 156.0
EH3_k127_4195909_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 545.0
EH3_k127_4195909_1 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 531.0
EH3_k127_4195909_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 473.0
EH3_k127_4195909_3 Belongs to the HMG-CoA reductase family K00021,K00054 GO:0003674,GO:0003824,GO:0004420,GO:0006629,GO:0006694,GO:0006720,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 1.1.1.34,1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 439.0
EH3_k127_4195909_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003008 265.0
EH3_k127_4195909_5 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000301 62.0
EH3_k127_4195909_6 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.000001185 58.0
EH3_k127_4195909_7 - - - - 0.000009252 51.0
EH3_k127_4195909_8 - - - - 0.0008562 43.0
EH3_k127_4206803_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 5.216e-217 683.0
EH3_k127_4220317_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 373.0
EH3_k127_4220317_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 316.0
EH3_k127_4220317_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000001189 113.0
EH3_k127_4220317_11 Putative transposase DNA-binding domain - - - 0.0000000000000000006619 98.0
EH3_k127_4220317_12 Ribosomal protein S27 K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000008973 83.0
EH3_k127_4220317_13 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000001643 72.0
EH3_k127_4220317_14 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0001107 49.0
EH3_k127_4220317_2 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007361 278.0
EH3_k127_4220317_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
EH3_k127_4220317_4 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000002348 237.0
EH3_k127_4220317_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000001209 185.0
EH3_k127_4220317_6 Binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000002531 162.0
EH3_k127_4220317_7 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000001112 122.0
EH3_k127_4220317_8 -acetyltransferase - - - 0.0000000000000000000000000002885 119.0
EH3_k127_4220317_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000003176 115.0
EH3_k127_4250504_0 NMD3 family K07562 - - 0.0000000000000000000000000000000000000000000000000000000000000000006719 240.0
EH3_k127_4250504_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000001441 124.0
EH3_k127_4250504_2 ABC-2 family transporter protein K01992 - - 0.00001486 51.0
EH3_k127_4252504_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 550.0
EH3_k127_4252504_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 349.0
EH3_k127_4252504_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 321.0
EH3_k127_4252504_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000001557 211.0
EH3_k127_4252504_4 PFAM GHMP kinase K06982 - 2.7.1.169 0.0000000000000000000000000000000000000000000000000009667 195.0
EH3_k127_4252504_5 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000000000002574 149.0
EH3_k127_4252504_6 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000006777 136.0
EH3_k127_4252504_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000002654 56.0
EH3_k127_4314248_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 374.0
EH3_k127_4314248_1 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.0000000000000000000000000000000000000000002522 169.0
EH3_k127_4314248_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000003584 100.0
EH3_k127_4338521_0 DNA polymerase type-B family K02319 - 2.7.7.7 4.409e-204 649.0
EH3_k127_4338521_1 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000007351 154.0
EH3_k127_4352509_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 6.386e-251 786.0
EH3_k127_4352509_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.224e-206 656.0
EH3_k127_4352509_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 462.0
EH3_k127_4352509_3 ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 409.0
EH3_k127_4352509_4 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001414 254.0
EH3_k127_4352509_5 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000001664 174.0
EH3_k127_4352509_6 - - - - 0.0000003244 56.0
EH3_k127_4379666_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 588.0
EH3_k127_4379666_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 348.0
EH3_k127_4379666_2 2Fe-2S iron-sulfur cluster binding domain K18210 - 1.3.4.1 0.0000000000000000000000000000000000000001209 162.0
EH3_k127_4379666_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000002313 58.0
EH3_k127_4382962_0 Conserved hypothetical ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001066 279.0
EH3_k127_4382962_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.00000000000000000000000227 104.0
EH3_k127_4382962_2 Protein of unknown function (DUF998) - - - 0.000000004561 58.0
EH3_k127_4382962_3 - K06193 - - 0.0001954 50.0
EH3_k127_4396094_0 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 357.0
EH3_k127_4396094_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 342.0
EH3_k127_4405867_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000006874 220.0
EH3_k127_4405867_1 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000002797 156.0
EH3_k127_4405867_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000003136 145.0
EH3_k127_4424101_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 535.0
EH3_k127_4424101_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 344.0
EH3_k127_4424101_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000001344 141.0
EH3_k127_4424101_3 DnaB-like helicase C terminal domain - - - 0.00000000000000000000000000000001024 136.0
EH3_k127_4424101_4 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000166 83.0
EH3_k127_4450604_0 tRNA synthetases class I (C) catalytic domain K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 574.0
EH3_k127_4450604_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 359.0
EH3_k127_4450604_2 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000001013 254.0
EH3_k127_4450604_3 Elongator protein 3 MiaB NifB - - - 0.00001269 55.0
EH3_k127_4465451_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 500.0
EH3_k127_4465451_1 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 453.0
EH3_k127_4465451_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 441.0
EH3_k127_4465451_3 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 368.0
EH3_k127_4465451_4 Oxidoreductase domain protein K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006409 281.0
EH3_k127_4465451_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000009975 181.0
EH3_k127_4465451_6 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000001657 116.0
EH3_k127_4465451_7 Belongs to the UPF0434 family - - - 0.0000000000005512 71.0
EH3_k127_4492999_0 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000001253 226.0
EH3_k127_4492999_1 - - - - 0.00000009391 60.0
EH3_k127_4529605_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 460.0
EH3_k127_4529605_1 of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 321.0
EH3_k127_4529605_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001785 274.0
EH3_k127_4529605_3 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008894 262.0
EH3_k127_4529605_4 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000006689 87.0
EH3_k127_4529605_5 - - - - 0.00004519 48.0
EH3_k127_4537399_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 315.0
EH3_k127_4537399_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000006241 175.0
EH3_k127_4537399_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001124 154.0
EH3_k127_4537399_3 PRC-barrel domain - - - 0.00000000000000000000000009 108.0
EH3_k127_457671_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 441.0
EH3_k127_457671_2 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001071 266.0
EH3_k127_457671_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001305 232.0
EH3_k127_457671_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000004842 206.0
EH3_k127_457671_5 - - - - 0.0000000000000000000000000000000003638 137.0
EH3_k127_457671_6 Winged helix-turn-helix - - - 0.000000000000000000000000000001137 123.0
EH3_k127_457671_7 - - - - 0.00000000000000000000000008904 115.0
EH3_k127_457671_8 FMN binding K03809 - 1.6.5.2 0.000000000008643 72.0
EH3_k127_4578398_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.519e-267 835.0
EH3_k127_4578398_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 418.0
EH3_k127_4578398_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K00591 GO:0003674,GO:0003824,GO:0004395,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0010420,GO:0016020,GO:0016740,GO:0016741,GO:0019866,GO:0019898,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0042180,GO:0042181,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0061542,GO:0061543,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.114,2.1.1.222,2.1.1.64 0.000009139 55.0
EH3_k127_4608084_0 Phosphomethylpyrimidine kinase K00941,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 339.0
EH3_k127_4608084_1 COG0438 Glycosyltransferase K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 297.0
EH3_k127_4608084_2 Uncharacterised ACR, YkgG family COG1556 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 303.0
EH3_k127_4608084_3 - - - - 0.000000000000000000000001041 109.0
EH3_k127_4608084_4 belongs to the lyase 1 family. Argininosuccinate lyase subfamily K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000003812 51.0
EH3_k127_4665033_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 528.0
EH3_k127_4665033_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000461 215.0
EH3_k127_4665033_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000005096 81.0
EH3_k127_4702402_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 466.0
EH3_k127_4721079_0 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000002762 195.0
EH3_k127_4721079_1 Roadblock LC7 family protein K07131 - - 0.000000000001793 72.0
EH3_k127_4721079_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000384 72.0
EH3_k127_4724344_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 358.0
EH3_k127_4724344_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000005433 150.0
EH3_k127_4724344_2 cobalamin binding K00548 - 2.1.1.13 0.0000000001848 63.0
EH3_k127_4742474_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 325.0
EH3_k127_4742474_1 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 301.0
EH3_k127_4758312_0 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 318.0
EH3_k127_4758312_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 312.0
EH3_k127_4758312_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 285.0
EH3_k127_4758312_3 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002135 250.0
EH3_k127_4758312_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000001039 198.0
EH3_k127_4758312_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000002341 141.0
EH3_k127_4758312_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000001682 86.0
EH3_k127_4781009_0 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 369.0
EH3_k127_4781009_1 - - - - 0.000000000000000000000000000000000000000000000003327 180.0
EH3_k127_4788553_0 Uroporphyrinogen decarboxylase (URO-D) K14082 - 2.1.1.247 0.0000000000000000000000000000000000000000000000000000000000000000002195 241.0
EH3_k127_4788553_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000004209 191.0
EH3_k127_4788553_2 DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000004005 176.0
EH3_k127_4788553_3 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000001893 166.0
EH3_k127_4788553_4 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000001757 136.0
EH3_k127_4799321_0 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000003542 230.0
EH3_k127_4799321_1 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000002574 220.0
EH3_k127_4799321_2 PFAM Xylose isomerase domain protein TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000004584 204.0
EH3_k127_4799321_3 methyltransferase K21459 - 2.1.1.301 0.000000000000000000000000000000000000000001289 167.0
EH3_k127_4799321_4 Participates in both transcription termination and antitermination K02600 - - 0.000199 53.0
EH3_k127_4816739_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003225 256.0
EH3_k127_4816739_1 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000004941 231.0
EH3_k127_4816739_10 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.000000000000000006769 85.0
EH3_k127_4816739_11 Glycosyltransferase like family 2 - - - 0.00000386 51.0
EH3_k127_4816739_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000001493 207.0
EH3_k127_4816739_3 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002191 201.0
EH3_k127_4816739_4 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003516 190.0
EH3_k127_4816739_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000003095 164.0
EH3_k127_4816739_6 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000643 119.0
EH3_k127_4816739_7 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000009198 109.0
EH3_k127_4816739_8 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000007045 105.0
EH3_k127_4816739_9 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001024 94.0
EH3_k127_486289_0 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 390.0
EH3_k127_486289_1 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000006542 228.0
EH3_k127_486289_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000003992 79.0
EH3_k127_4871749_0 GTPase of unknown function C-terminal K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 460.0
EH3_k127_4871749_1 DNA polymerase type-B family K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
EH3_k127_4871749_2 Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000001007 73.0
EH3_k127_4893395_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
EH3_k127_4893395_1 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000005756 184.0
EH3_k127_4893395_2 NMT1-like family K02051 - - 0.000000000000000000000003141 113.0
EH3_k127_4893395_3 - - - - 0.000000005577 63.0
EH3_k127_4895759_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 372.0
EH3_k127_4895759_1 Thiamine-binding protein - - - 0.00000000000000000000009731 102.0
EH3_k127_4895759_2 - - - - 0.000000000000000148 83.0
EH3_k127_4921933_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 379.0
EH3_k127_4921933_1 methyltransferase - - - 0.00000000000000001064 91.0
EH3_k127_4939984_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 373.0
EH3_k127_4939984_1 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000001216 218.0
EH3_k127_4939984_2 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000002402 134.0
EH3_k127_4939984_3 of the drug metabolite transporter (DMT) superfamily - - - 0.000003815 50.0
EH3_k127_4941014_0 - - - - 0.0000000000000000000000000008018 115.0
EH3_k127_4941014_1 cobalamin synthesis protein - - - 0.000000000000000000000009697 106.0
EH3_k127_4952315_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000005307 260.0
EH3_k127_4952315_1 Cysteine-rich domain - - - 0.0000001712 53.0
EH3_k127_4952315_2 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00001817 49.0
EH3_k127_4952315_3 BioY family - - - 0.0002045 45.0
EH3_k127_4962627_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000001195 239.0
EH3_k127_4962627_1 RNA secondary structure unwinding K03724 - - 0.00000000000000000000000128 109.0
EH3_k127_4977177_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 345.0
EH3_k127_4977177_1 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000000000002073 159.0
EH3_k127_4977177_2 Uncharacterized ArCR, COG1888 K09732 - - 0.000000000000000000000000000000001763 131.0
EH3_k127_4977177_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.0000000000000000001294 91.0
EH3_k127_4999757_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 441.0
EH3_k127_4999757_1 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 306.0
EH3_k127_4999757_2 PQ loop repeat K15383 - - 0.0000000000000002601 81.0
EH3_k127_4999757_3 - - - - 0.000000000001289 73.0
EH3_k127_5019400_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 484.0
EH3_k127_5019400_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 475.0
EH3_k127_5019400_2 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 424.0
EH3_k127_5019400_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000304 209.0
EH3_k127_5019400_4 Iron dependent K03709 - - 0.000000000000000000000000000000000000000000000001996 181.0
EH3_k127_5019400_5 Elongator protein 3 MiaB NifB - - - 0.00000000000000000002421 93.0
EH3_k127_5067443_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 427.0
EH3_k127_5067443_1 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000009461 178.0
EH3_k127_5067443_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000001249 160.0
EH3_k127_507914_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000000009681 235.0
EH3_k127_507914_1 - - - - 0.000000000000000000002094 104.0
EH3_k127_507914_2 NUDIX domain K03574 - 3.6.1.55 0.000000000000001141 82.0
EH3_k127_507914_3 - - - - 0.000000000000009754 76.0
EH3_k127_5083948_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 494.0
EH3_k127_5083948_1 RNA-binding protein of the translin family K07477 - - 0.000000000000000000000000000000000000000000003722 171.0
EH3_k127_5083948_2 Thioredoxin K03671 - - 0.00000000000000000000000164 107.0
EH3_k127_5083948_3 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.00009708 55.0
EH3_k127_515273_0 Fibronectin type III domain K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 429.0
EH3_k127_515273_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000006227 180.0
EH3_k127_515273_2 Glycosyl transferase 4-like - - - 0.00000000000000000000000000001049 133.0
EH3_k127_515273_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000008812 105.0
EH3_k127_515273_4 PFAM Glycosyl transferase, group 1 K13668 - 2.4.1.346 0.00000000000000000003035 103.0
EH3_k127_515273_5 Protein of unknown function (DUF1616) - - - 0.000000000000006135 86.0
EH3_k127_515273_6 Protein of unknown function (DUF1698) - - - 0.0000000000000062 84.0
EH3_k127_515273_7 SMART Elongator protein 3 MiaB NifB - - - 0.000000000008055 71.0
EH3_k127_5175599_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 614.0
EH3_k127_5196803_0 PEP-utilising enzyme, mobile domain K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 532.0
EH3_k127_5196803_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 462.0
EH3_k127_5196803_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 425.0
EH3_k127_5196803_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000005572 196.0
EH3_k127_5196803_4 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000002002 124.0
EH3_k127_5199427_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 372.0
EH3_k127_5199427_1 secreted hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002348 237.0
EH3_k127_5232709_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 7.946e-307 963.0
EH3_k127_5232709_1 - - - - 0.00000000000000000000000004648 108.0
EH3_k127_5232709_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000004906 69.0
EH3_k127_5238131_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000006076 171.0
EH3_k127_5238131_1 Multi-sensor signal transduction histidine kinase - - - 0.000000000000002668 87.0
EH3_k127_5238131_2 - - - - 0.00000000563 60.0
EH3_k127_5251835_0 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000009808 147.0
EH3_k127_5251835_1 PFAM thioesterase superfamily K02614 - - 0.0000000000000000002714 93.0
EH3_k127_5259787_0 Anticodon binding domain K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 296.0
EH3_k127_5259787_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007893 278.0
EH3_k127_5259787_2 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000004329 251.0
EH3_k127_5259787_3 Universal stress protein family - - - 0.0000000000000000000000000000000000000001751 154.0
EH3_k127_530486_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1118.0
EH3_k127_530486_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 296.0
EH3_k127_530486_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001972 243.0
EH3_k127_530486_3 zinc transporter K07238 - - 0.00000000000000002467 84.0
EH3_k127_530486_4 membrane - - - 0.0000002232 60.0
EH3_k127_5320650_0 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 384.0
EH3_k127_5320650_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 307.0
EH3_k127_5320650_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000006689 215.0
EH3_k127_538021_0 peptidase U62, modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 395.0
EH3_k127_538021_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000007405 143.0
EH3_k127_5428625_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 329.0
EH3_k127_5428625_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001638 228.0
EH3_k127_5428625_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000004732 176.0
EH3_k127_5428625_3 - - - - 0.0000008514 52.0
EH3_k127_5428625_4 Evidence 5 No homology to any previously reported sequences - - - 0.0001453 51.0
EH3_k127_5457415_0 ABC transporter K06158 - - 0.000000000000003412 77.0
EH3_k127_5457415_1 Kelch repeat type 1 - - - 0.00000000000001908 86.0
EH3_k127_5457415_3 Archaeal Type IV pilin, N-terminal - - - 0.000001202 62.0
EH3_k127_5496716_0 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 501.0
EH3_k127_5496716_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 414.0
EH3_k127_5496716_2 Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 338.0
EH3_k127_5496716_3 FAD binding domain - - - 0.000000000000000000000000000000000000000005297 158.0
EH3_k127_5513763_0 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 324.0
EH3_k127_5513763_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 301.0
EH3_k127_5513763_2 PHP-associated - - - 0.00000001305 58.0
EH3_k127_5518552_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 546.0
EH3_k127_5518552_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601,K08965 - 4.1.1.39,5.3.2.5 0.000000000000000000000000000000000000000000002743 167.0
EH3_k127_5518552_2 - - - - 0.00000000000000000616 94.0
EH3_k127_552297_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 509.0
EH3_k127_5553005_0 COG0531 Amino acid transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 417.0
EH3_k127_5553005_1 Methanogenesis marker protein 8 - - - 0.00000000000000000000000000000000000000000000000000002505 198.0
EH3_k127_5553005_2 DHHA1 domain K07463 - - 0.00000000003477 74.0
EH3_k127_55638_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
EH3_k127_55638_1 structural constituent of ribosome K02912 - - 0.00000000000000000000000000000000000000000000000000003208 201.0
EH3_k127_55638_2 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000009854 181.0
EH3_k127_55638_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001342 134.0
EH3_k127_55638_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000003912 66.0
EH3_k127_5623844_0 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 304.0
EH3_k127_5623844_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000006421 171.0
EH3_k127_5623844_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000003987 153.0
EH3_k127_5623844_3 Cytidylyltransferase K19712 - 2.7.7.62 0.00000000000000000000000000003047 132.0
EH3_k127_5631836_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 446.0
EH3_k127_5631836_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 439.0
EH3_k127_5631836_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000004144 222.0
EH3_k127_5631836_3 OsmC-like protein - - - 0.000000000000000000000000000000000008897 140.0
EH3_k127_5631836_4 PFAM CobW HypB UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000004702 141.0
EH3_k127_5631836_5 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000000000005181 102.0
EH3_k127_5642168_0 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 414.0
EH3_k127_5642168_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
EH3_k127_5642168_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000001413 180.0
EH3_k127_5642168_3 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000001202 121.0
EH3_k127_5642168_4 - - - - 0.0000000000000000000000922 98.0
EH3_k127_5699930_0 Oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 557.0
EH3_k127_5699930_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000174 233.0
EH3_k127_5717240_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 621.0
EH3_k127_5717240_1 4Fe-4S single cluster domain K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 373.0
EH3_k127_5717240_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000006033 261.0
EH3_k127_5717240_3 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000000000000000001651 178.0
EH3_k127_5797586_0 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000003573 245.0
EH3_k127_5797586_1 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000377 198.0
EH3_k127_5797586_2 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000001526 179.0
EH3_k127_5826492_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 4.607e-229 717.0
EH3_k127_5826492_1 Peptidase family M50 - - - 0.0000000000000000000000003048 109.0
EH3_k127_5844353_0 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 394.0
EH3_k127_5844353_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001939 300.0
EH3_k127_5844353_2 DHHA1 domain K07463 - - 0.000000000000000000000002086 105.0
EH3_k127_5844353_3 SPFH domain-Band 7 family - - - 0.0000263 52.0
EH3_k127_584967_0 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 511.0
EH3_k127_5877607_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1405.0
EH3_k127_5877607_1 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 421.0
EH3_k127_5877607_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000002586 141.0
EH3_k127_5889658_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 410.0
EH3_k127_5889658_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 308.0
EH3_k127_5889658_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000004621 128.0
EH3_k127_5889658_3 4Fe-4S dicluster domain K00188 - 1.2.7.7 0.000000000000000000000000000003099 123.0
EH3_k127_5899730_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.638e-197 624.0
EH3_k127_5918942_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
EH3_k127_5918942_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008991 237.0
EH3_k127_5918942_2 Protein of unknown function (DUF531) K09725 - - 0.00000000000000000000000000000000000000000000000000000000108 206.0
EH3_k127_5918942_3 phosphoribosylformylglycinamidine cyclo-ligase activity K01933 - 6.3.3.1 0.00000000000000000000000000000000000000307 150.0
EH3_k127_5960415_0 Amino acid permease - - - 0.0000000000000002356 85.0
EH3_k127_5960415_1 Small multi-drug export protein - - - 0.000000000000004301 87.0
EH3_k127_5960415_2 DnaB-like helicase C terminal domain K08482 - - 0.000001536 58.0
EH3_k127_5966964_0 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 335.0
EH3_k127_5966964_1 COG0471 Di- and tricarboxylate transporters K14445 - - 0.000000000000000000000000000000000000000000000000000000003676 217.0
EH3_k127_5966964_2 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000001497 133.0
EH3_k127_5966964_3 FR47-like protein - - - 0.000000000000000000000003256 107.0
EH3_k127_5966964_4 4Fe-4S dicluster domain K14091 - - 0.0000000000000000000007638 98.0
EH3_k127_5966964_5 endonuclease activity K07451 - - 0.0000000000437 71.0
EH3_k127_5991583_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000003482 179.0
EH3_k127_5991583_1 Transcriptional regulator K07722 - - 0.000000000000000000000000004393 115.0
EH3_k127_6026710_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000009801 208.0
EH3_k127_6026710_1 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000006547 179.0
EH3_k127_6026710_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000001789 155.0
EH3_k127_6026710_3 Acetyltransferase (GNAT) domain - - - 0.000008192 54.0
EH3_k127_6046250_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 372.0
EH3_k127_6046250_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003525 243.0
EH3_k127_6046250_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.0000000342 56.0
EH3_k127_6050228_0 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 289.0
EH3_k127_6050228_1 ferredoxin oxidoreductase K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000001972 192.0
EH3_k127_6060483_0 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 359.0
EH3_k127_6066992_0 4Fe-4S ferredoxin iron-sulfur binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001497 283.0
EH3_k127_6066992_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000471 239.0
EH3_k127_6066992_2 protein conserved in archaea - - - 0.00000000000000000000000000000000000000000000000000002734 199.0
EH3_k127_6066992_3 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000009812 173.0
EH3_k127_6066992_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000002331 130.0
EH3_k127_6066992_5 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000005554 108.0
EH3_k127_6066992_6 - - - - 0.0000000006081 67.0
EH3_k127_6066992_7 - - - - 0.00005974 51.0
EH3_k127_6089010_0 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 347.0
EH3_k127_6089010_1 - - - - 0.0000000000000000000005243 108.0
EH3_k127_6089010_2 Protein of unknown function DUF131 - - - 0.00000284 54.0
EH3_k127_6216165_0 Acyl-CoA synthetase (NDP forming) K09181 - - 7.619e-197 636.0
EH3_k127_6216165_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004748 245.0
EH3_k127_6216165_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000326 226.0
EH3_k127_6216165_3 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000001901 153.0
EH3_k127_6216165_4 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.00000000007725 64.0
EH3_k127_6216165_5 - - - - 0.00003883 50.0
EH3_k127_6251064_0 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 371.0
EH3_k127_6251064_1 Sugar (and other) transporter - - - 0.00000072 59.0
EH3_k127_6255472_0 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000001233 180.0
EH3_k127_6255472_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000001843 163.0
EH3_k127_6255472_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000003314 64.0
EH3_k127_6269721_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003547 265.0
EH3_k127_6269721_1 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001902 249.0
EH3_k127_6269721_2 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000009979 162.0
EH3_k127_6269721_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000000000000000000000000001575 151.0
EH3_k127_6269721_4 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000009063 139.0
EH3_k127_6281540_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 442.0
EH3_k127_6281540_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 327.0
EH3_k127_6281540_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000001506 136.0
EH3_k127_6301099_0 Radical_SAM C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001186 228.0
EH3_k127_6301099_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685,K07053 - 3.1.26.3,3.1.3.97 0.000000000000000000000000000000000000000000000000000537 190.0
EH3_k127_6301099_2 signal transduction protein - - - 0.00000004624 58.0
EH3_k127_6340857_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 463.0
EH3_k127_6340857_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000001019 207.0
EH3_k127_6340857_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000006691 165.0
EH3_k127_6340857_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000000002231 120.0
EH3_k127_6340857_4 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000003302 98.0
EH3_k127_6346449_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.048e-222 699.0
EH3_k127_6346449_1 Methyl-viologen-reducing hydrogenase, delta subunit K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000001041 171.0
EH3_k127_6346449_2 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000007248 120.0
EH3_k127_6346449_3 response regulator - - - 0.0000000000000000006028 89.0
EH3_k127_6346449_4 - - - - 0.000002014 51.0
EH3_k127_6346449_5 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0005181 51.0
EH3_k127_6352455_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 469.0
EH3_k127_6352455_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 475.0
EH3_k127_6352455_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003631 278.0
EH3_k127_6352455_3 COG1522 Transcriptional regulators K03718 - - 0.0000000000000000000000000000000000000000000002059 172.0
EH3_k127_6352455_4 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.0000000000000000000000003116 108.0
EH3_k127_6352455_5 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000001083 96.0
EH3_k127_6352455_6 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000002571 104.0
EH3_k127_6352455_7 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000000102 87.0
EH3_k127_6352764_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 5.258e-204 646.0
EH3_k127_6352764_1 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 378.0
EH3_k127_6352764_2 NADH-quinone oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001199 272.0
EH3_k127_6352764_3 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 0.0000000000000000000000000000000000000000002288 165.0
EH3_k127_6429638_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002223 292.0
EH3_k127_6429638_1 PFAM Histone deacetylase K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 267.0
EH3_k127_6429638_2 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000101 258.0
EH3_k127_6429638_3 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000003186 111.0
EH3_k127_6429638_4 - - - - 0.00000001459 61.0
EH3_k127_6444660_0 - - - - 0.0000000000000223 82.0
EH3_k127_6444660_1 Secreted protein with C-terminal beta-propeller domain - - - 0.00000000000007417 77.0
EH3_k127_6444660_2 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000001094 68.0
EH3_k127_6444660_3 regulatory protein, arsR K13771 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000182 72.0
EH3_k127_6472522_0 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
EH3_k127_6472522_1 coproporphyrinogen III oxidase - - - 0.000000000000000000000000000000000000000005087 172.0
EH3_k127_6472522_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000003143 154.0
EH3_k127_654620_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 463.0
EH3_k127_654620_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000002241 128.0
EH3_k127_6575526_0 TIGRFAM Glycerol-3-phosphate dehydrogenase, anaerobic A subunit K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 381.0
EH3_k127_6575526_1 TIGRFAM Glycerol-3-phosphate dehydrogenase, anaerobic B subunit K00112 - 1.1.5.3 0.00000001481 66.0
EH3_k127_6590915_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 335.0
EH3_k127_6590915_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000007139 61.0
EH3_k127_6599689_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 602.0
EH3_k127_6599689_1 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 489.0
EH3_k127_6599689_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000989 269.0
EH3_k127_6599689_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000003434 263.0
EH3_k127_6599689_4 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003915 256.0
EH3_k127_6599689_5 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000292 249.0
EH3_k127_6599689_6 Flavodoxin - GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000001175 157.0
EH3_k127_6599689_7 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000004006 94.0
EH3_k127_6599689_8 - - - - 0.00001191 54.0
EH3_k127_6635025_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K03885,K17870 - 1.6.3.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 504.0
EH3_k127_6635025_1 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000001246 229.0
EH3_k127_6639721_0 Belongs to the UPF0292 family - - - 0.000000000000000000002686 100.0
EH3_k127_6639721_1 Belongs to the UPF0235 family K09131 - - 0.0000000000000000003503 91.0
EH3_k127_6639721_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000006415 79.0
EH3_k127_6639721_3 protein conserved in archaea K09723 - - 0.00000001642 64.0
EH3_k127_665903_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 529.0
EH3_k127_665903_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 367.0
EH3_k127_665903_2 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 302.0
EH3_k127_6670022_0 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 580.0
EH3_k127_6670022_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 459.0
EH3_k127_6670022_2 Calcineurin-like phosphoesterase superfamily domain K01090 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 369.0
EH3_k127_6670022_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000001056 128.0
EH3_k127_6670022_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000005745 66.0
EH3_k127_6672225_0 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000546 113.0
EH3_k127_6672225_1 RND superfamily K06994 - - 0.0000000000000000000008345 110.0
EH3_k127_6672225_2 Sulfate transporter antisigma-factor antagonist STAS - - - 0.000004166 56.0
EH3_k127_672049_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 604.0
EH3_k127_672049_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 436.0
EH3_k127_672049_2 PP-loop family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 333.0
EH3_k127_672049_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 295.0
EH3_k127_672049_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000006511 128.0
EH3_k127_672049_5 cheY-homologous receiver domain K07668 - - 0.00000000000000000000061 107.0
EH3_k127_672049_6 Ribosomal_L40e K02927 - - 0.0000000000000007366 79.0
EH3_k127_6730448_0 Isocitrate/isopropylmalate dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 580.0
EH3_k127_6730448_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000005998 233.0
EH3_k127_6730448_2 Papain family cysteine protease - - - 0.000000000000000000000000012 116.0
EH3_k127_6730448_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000001502 73.0
EH3_k127_6739732_0 Alkyl sulfatase dimerisation - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006790,GO:0006805,GO:0008150,GO:0008152,GO:0008484,GO:0009410,GO:0009987,GO:0016787,GO:0016788,GO:0018741,GO:0018909,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043436,GO:0044237,GO:0044281,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071466,GO:0071704 - 1.887e-224 708.0
EH3_k127_6739732_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 555.0
EH3_k127_6739732_2 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 423.0
EH3_k127_6739732_3 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000001644 176.0
EH3_k127_6739732_4 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000001301 168.0
EH3_k127_6739732_5 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000005181 102.0
EH3_k127_6739732_6 Ribosomal protein L37e K02922 - - 0.0000000000000000003322 87.0
EH3_k127_6744771_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
EH3_k127_6744771_1 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000004549 213.0
EH3_k127_6744771_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000001685 164.0
EH3_k127_6744771_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000001255 126.0
EH3_k127_6744771_4 Diphthamide K07561 - 2.5.1.108 0.0000008472 51.0
EH3_k127_6744899_0 KH domain K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 475.0
EH3_k127_6744899_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000002146 233.0
EH3_k127_6744899_2 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000001804 121.0
EH3_k127_6744899_3 formylmethanofuran dehydrogenase, subunit E - - - 0.0000000000000001869 85.0
EH3_k127_6744899_4 - - - - 0.00000000005244 69.0
EH3_k127_6756340_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 356.0
EH3_k127_6756340_1 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000002501 233.0
EH3_k127_6768275_0 PFAM Beta propeller domain K14475 - - 0.000000000000000000000000000000000000000000000000000000000000000000006322 253.0
EH3_k127_6768275_1 TIGRFAM arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.0000000000000000000000000000000000000000000000000000003445 204.0
EH3_k127_6768275_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000239 196.0
EH3_k127_67809_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 408.0
EH3_k127_6804518_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 446.0
EH3_k127_6804518_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000003648 196.0
EH3_k127_6804518_2 Protein of unknown function DUF58 - - - 0.000000005659 65.0
EH3_k127_6837205_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 391.0
EH3_k127_6837205_1 Aminotransferase class I and II K00639 - 2.3.1.29 0.00000000000000000000000000000000000000004277 155.0
EH3_k127_6837205_2 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000007001 111.0
EH3_k127_6837205_3 Methyltransferase - - - 0.000172 49.0
EH3_k127_6845473_0 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 394.0
EH3_k127_6845473_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001715 259.0
EH3_k127_6845473_2 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000001197 223.0
EH3_k127_6845473_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000007215 144.0
EH3_k127_6845473_4 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001073 85.0
EH3_k127_6853430_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 352.0
EH3_k127_6853430_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 285.0
EH3_k127_6853430_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025,K08723 - 3.1.3.5 0.000000000000000000000002813 112.0
EH3_k127_6853430_3 HNH endonuclease - - - 0.0004613 51.0
EH3_k127_6860906_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003092 276.0
EH3_k127_6860906_1 aminotransferase - - - 0.00000000000000000000000000000001887 136.0
EH3_k127_6872266_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 334.0
EH3_k127_6872266_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 315.0
EH3_k127_6872266_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003173 267.0
EH3_k127_6872266_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000004262 197.0
EH3_k127_6872266_4 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000416 97.0
EH3_k127_6891683_0 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 504.0
EH3_k127_6891683_1 ATPases associated with a variety of cellular activities K10112,K17240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 398.0
EH3_k127_6891683_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 381.0
EH3_k127_6891683_3 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 367.0
EH3_k127_6891683_4 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000006123 219.0
EH3_k127_6891683_5 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000004423 190.0
EH3_k127_6891683_6 TIGRFAM segregation and condensation protein B K06024 - - 0.00000000000000000000000000000000000000001326 158.0
EH3_k127_6891683_7 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000001686 149.0
EH3_k127_6891683_8 snRNP Sm proteins K04796 - - 0.00000000000000000000001888 100.0
EH3_k127_6927747_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 319.0
EH3_k127_6927747_1 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000243 250.0
EH3_k127_6927747_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000003229 153.0
EH3_k127_6930037_0 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 9.479e-228 721.0
EH3_k127_6930037_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.2,1.4.1.3,1.4.1.4 2.248e-205 649.0
EH3_k127_6930037_2 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000352 278.0
EH3_k127_6930037_3 NADH-quinone oxidoreductase, E subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.000000000000000000000000000000000005066 143.0
EH3_k127_6951415_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000002973 233.0
EH3_k127_6951415_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000004442 197.0
EH3_k127_6988511_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 409.0
EH3_k127_6988511_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 310.0
EH3_k127_6988511_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000001398 100.0
EH3_k127_6988511_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000001465 89.0
EH3_k127_7016180_0 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000003824 130.0
EH3_k127_7016180_1 permease - - - 0.00003382 55.0
EH3_k127_7036069_0 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008123 266.0
EH3_k127_7036069_1 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000005829 177.0
EH3_k127_7036069_2 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000009925 173.0
EH3_k127_7036069_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000003455 179.0
EH3_k127_7036069_4 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000000008577 149.0
EH3_k127_7036069_5 Oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000002859 141.0
EH3_k127_7036069_6 Domain of unknown function (DUF362) - - - 0.000000000000000004181 87.0
EH3_k127_704695_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 535.0
EH3_k127_704695_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 528.0
EH3_k127_7094568_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 417.0
EH3_k127_7094568_1 Alternative locus ID - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009937 291.0
EH3_k127_7094568_2 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00000000000000000000000000000000000000000000000000000000003615 209.0
EH3_k127_7094568_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000003303 75.0
EH3_k127_7094978_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001121 252.0
EH3_k127_7094978_1 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000002726 158.0
EH3_k127_7094978_2 Peptidase family S51 - - - 0.00000000843 61.0
EH3_k127_7159167_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000004928 157.0
EH3_k127_7159167_1 Periplasmic Protein - - - 0.000000000000000000000000000000001504 135.0
EH3_k127_7159167_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000002056 84.0
EH3_k127_7159167_3 - - - - 0.000006211 52.0
EH3_k127_7205828_0 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001998 259.0
EH3_k127_7205828_1 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000006304 208.0
EH3_k127_7205828_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000008412 179.0
EH3_k127_7205828_3 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001879 85.0
EH3_k127_7205828_4 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.000000000008076 73.0
EH3_k127_7205828_5 zinc-ribbon domain - - - 0.0002575 49.0
EH3_k127_7239065_0 fumarate reductase K18210 - 1.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 351.0
EH3_k127_7239065_1 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000004017 190.0
EH3_k127_7239065_2 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000004713 179.0
EH3_k127_7239065_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000009447 106.0
EH3_k127_7239065_4 succinate dehydrogenase K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 0.0000000000000000002608 91.0
EH3_k127_7239065_5 - - - - 0.0000000000001691 78.0
EH3_k127_7248259_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000391 177.0
EH3_k127_7248259_1 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000004455 109.0
EH3_k127_7248259_2 helicase K10844 - 3.6.4.12 0.0002746 48.0
EH3_k127_7249982_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.023e-267 838.0
EH3_k127_7249982_1 Protein of unknown function DUF89 K09116 - - 0.0000000000000775 76.0
EH3_k127_7256429_0 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000001125 247.0
EH3_k127_7256429_1 Belongs to the UPF0280 family K09740 - - 0.000000000000000000000000000000000000000000000000000000000003398 216.0
EH3_k127_7256429_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000754 189.0
EH3_k127_7256429_3 Helix-turn-helix domain - - - 0.000000000000000006889 91.0
EH3_k127_7264714_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.958e-222 702.0
EH3_k127_7264714_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 349.0
EH3_k127_7264714_2 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 310.0
EH3_k127_7264714_3 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005342 290.0
EH3_k127_7264714_4 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
EH3_k127_7264714_5 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000005311 229.0
EH3_k127_7264714_6 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000001798 162.0
EH3_k127_7264714_7 xylanase chitin deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000002763 160.0
EH3_k127_7264714_8 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000006855 123.0
EH3_k127_7267234_0 PFAM CBS domain K03281 - - 0.0000000000000000000000000001334 129.0
EH3_k127_7267234_1 - - - - 0.00000000000001088 83.0
EH3_k127_7302338_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
EH3_k127_7302338_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000001217 168.0
EH3_k127_7302338_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000001943 124.0
EH3_k127_7302338_3 Histidine phosphatase superfamily (branch 1) - - - 0.0000007946 59.0
EH3_k127_7302338_4 universal stress protein - - - 0.000001314 60.0
EH3_k127_7302338_5 membrane - - - 0.0001228 47.0
EH3_k127_7363608_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.066e-306 979.0
EH3_k127_7363608_1 NUDIX domain - - - 0.000000000002353 69.0
EH3_k127_7385425_0 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 5.735e-196 623.0
EH3_k127_7385425_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 388.0
EH3_k127_7385425_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000005733 265.0
EH3_k127_7385425_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000002152 186.0
EH3_k127_7385425_4 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 0.000000000000000000000000000000000000000000003594 166.0
EH3_k127_7390461_0 Metallopeptidase family M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 308.0
EH3_k127_7390461_1 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006047 270.0
EH3_k127_7390461_2 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000004102 96.0
EH3_k127_7390461_3 Putative modulator of DNA gyrase K03568 - - 0.00007035 49.0
EH3_k127_7390728_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000008566 264.0
EH3_k127_7390728_1 - - - - 0.000000000000001434 85.0
EH3_k127_7399595_0 snoRNA binding domain, fibrillarin K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005039 246.0
EH3_k127_7407128_1 transposase activity - - - 0.000000000000008621 81.0
EH3_k127_7485188_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 388.0
EH3_k127_7485188_1 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 355.0
EH3_k127_7485188_2 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 339.0
EH3_k127_7485188_3 Isocitrate/isopropylmalate dehydrogenase K00030,K00052,K07246,K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.41,1.1.1.83,1.1.1.85,1.1.1.87,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 291.0
EH3_k127_7485188_4 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001023 275.0
EH3_k127_7485188_5 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000121 225.0
EH3_k127_7485188_6 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000008246 211.0
EH3_k127_7485188_7 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000001307 94.0
EH3_k127_7496564_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001677 257.0
EH3_k127_7496564_1 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000005663 116.0
EH3_k127_7496564_2 - - - - 0.00000000004335 68.0
EH3_k127_7506948_0 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000584 186.0
EH3_k127_7506948_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000001678 131.0
EH3_k127_7565754_0 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009796 268.0
EH3_k127_7565754_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000008903 222.0
EH3_k127_7587982_0 DEAD/H associated K03724 - - 2.817e-233 737.0
EH3_k127_7587982_1 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 462.0
EH3_k127_7587982_2 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000000001147 75.0
EH3_k127_7587982_3 glyoxalase III activity - - - 0.00000007156 57.0
EH3_k127_7587982_4 Rubrerythrin - - - 0.00002583 53.0
EH3_k127_7641266_0 MCM OB domain K10726 - - 1.176e-202 661.0
EH3_k127_7641266_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000866 163.0
EH3_k127_7641266_2 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000007197 113.0
EH3_k127_7641266_3 NMD3 family K07562 - - 0.00000000001004 67.0
EH3_k127_7682592_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 512.0
EH3_k127_7682592_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 387.0
EH3_k127_7682592_2 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 290.0
EH3_k127_7682592_3 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000554 177.0
EH3_k127_7682592_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000004627 165.0
EH3_k127_7682592_5 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000005014 120.0
EH3_k127_7692234_0 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 390.0
EH3_k127_7834478_0 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
EH3_k127_7834478_1 DNA binding protein K06930 - - 0.000000000000000000000000005885 120.0
EH3_k127_7902143_0 ABC transporter K00400,K16786,K16787 - - 1.286e-220 696.0
EH3_k127_7902143_1 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 589.0
EH3_k127_7902143_2 PFAM Methyl-coenzyme M reductase K03421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 326.0
EH3_k127_7902143_3 Domain of unknown function (DUF4443) - - - 0.00000000000000000000000000000000000000000000000000000000000000004283 234.0
EH3_k127_7902143_4 - - - - 0.000000000000000000000000000000000002927 143.0
EH3_k127_7902143_5 - - - - 0.00000000005694 68.0
EH3_k127_7902143_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000008335 66.0
EH3_k127_7902143_7 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.000000002744 61.0
EH3_k127_7924173_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 353.0
EH3_k127_7924173_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000001419 177.0
EH3_k127_7924173_2 Methyltransferase domain K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000006526 163.0
EH3_k127_7924173_3 archaeal Zn-finger protein - - - 0.000000000000000000000000000002522 126.0
EH3_k127_7924173_4 PFAM Rhomboid family protein K07059 - - 0.000000000000000000000006566 112.0
EH3_k127_793990_0 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001098 243.0
EH3_k127_793990_1 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000002297 247.0
EH3_k127_793990_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000005659 177.0
EH3_k127_793990_3 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000001186 101.0
EH3_k127_793990_4 Right handed beta helix region - - - 0.0000000000000000000001978 115.0
EH3_k127_793990_5 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000004993 111.0
EH3_k127_793990_6 Belongs to the Fur family K09825 - - 0.00000000000000000003499 96.0
EH3_k127_8002353_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1124.0
EH3_k127_8002353_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000003651 201.0
EH3_k127_8002353_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000001481 183.0
EH3_k127_8002353_3 Diacylglycerol kinase catalytic domain K00858 - 2.7.1.23 0.00000000000000000000000000000000000004401 149.0
EH3_k127_8002353_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000009813 107.0
EH3_k127_8002353_5 - - - - 0.00004407 50.0
EH3_k127_8037154_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 391.0
EH3_k127_8037154_1 C-terminal region of MMR_HSR1 domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002633 271.0
EH3_k127_8037154_2 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000001014 61.0
EH3_k127_8045953_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 5.694e-222 706.0
EH3_k127_8045953_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 535.0
EH3_k127_8045953_2 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 307.0
EH3_k127_8045953_3 TIGRFAM small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000005274 207.0
EH3_k127_8045953_4 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000001275 132.0
EH3_k127_8045953_5 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000004017 124.0
EH3_k127_8045953_6 SPFH domain-Band 7 family - - - 0.0003425 52.0
EH3_k127_8065774_0 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 348.0
EH3_k127_8065774_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 326.0
EH3_k127_8065774_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005751 287.0
EH3_k127_8065774_3 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002556 257.0
EH3_k127_8065774_4 - - - - 0.00000000000000000007047 94.0
EH3_k127_8096053_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 361.0
EH3_k127_8096053_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000001102 189.0
EH3_k127_8096053_2 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000001689 174.0
EH3_k127_8096053_3 Transglutaminase-like superfamily - - - 0.00000004805 58.0
EH3_k127_8107835_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 358.0
EH3_k127_8107835_1 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000007124 218.0
EH3_k127_8107835_2 Sulfurtransferase TusA - - - 0.000000000000000000005684 95.0
EH3_k127_8125166_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
EH3_k127_8168619_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 463.0
EH3_k127_8168619_1 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.00000000000000002335 83.0
EH3_k127_8182982_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005909 268.0
EH3_k127_8182982_1 aminopeptidase activity K19689 - - 0.000000000000000000000000000000000000000000000000000000000000003998 221.0
EH3_k127_8182982_2 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000302 175.0
EH3_k127_8182982_3 ABC-2 family transporter protein K01992 - - 0.0000000000001165 80.0
EH3_k127_8182982_4 ABC transporter, ATP-binding protein K01990 - - 0.0000000000003555 75.0
EH3_k127_8182982_5 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000004464 64.0
EH3_k127_8195309_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006648 277.0
EH3_k127_8195309_1 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000006807 126.0
EH3_k127_8195309_2 protein conserved in archaea - - - 0.000001627 52.0
EH3_k127_8199171_0 Rad51 - - - 0.0000000000000000000000000000000000000000000000000000002335 203.0
EH3_k127_8199171_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000031 157.0
EH3_k127_8199171_2 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000002945 55.0
EH3_k127_8199171_3 Pfam:DUF1628 - - - 0.000002905 53.0
EH3_k127_8218192_0 AAA domain K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 614.0
EH3_k127_8218192_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006189 255.0
EH3_k127_8218192_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000001694 190.0
EH3_k127_8218192_3 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000006351 92.0
EH3_k127_823230_0 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000000000000002339 159.0
EH3_k127_823230_1 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000001047 109.0
EH3_k127_823230_2 Rieske-like [2Fe-2S] domain - - - 0.00000000000000003927 85.0
EH3_k127_823230_3 COG2015, Alkyl sulfatase and related hydrolases - - - 0.000000152 55.0
EH3_k127_8234340_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 473.0
EH3_k127_8234340_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000003965 76.0
EH3_k127_8286461_0 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 320.0
EH3_k127_8286461_1 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000001496 168.0
EH3_k127_8286461_2 COG1522 Transcriptional regulators K03718 - - 0.00000000000000000000005964 104.0
EH3_k127_8286461_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000003517 69.0
EH3_k127_8324853_0 Belongs to the peptidase S16 family - - - 2.819e-259 821.0
EH3_k127_8324853_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 315.0
EH3_k127_8324853_2 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000003403 163.0
EH3_k127_8324853_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000001209 77.0
EH3_k127_8358296_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 569.0
EH3_k127_8358296_1 to cation transporters K07244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 332.0
EH3_k127_8358296_2 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000003757 87.0
EH3_k127_8358296_3 Cna protein B-type domain - - - 0.0000000000000000684 96.0
EH3_k127_8383787_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
EH3_k127_8383787_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000003351 219.0
EH3_k127_8383787_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.000000000000000000000000000000000000000000000000000000001018 214.0
EH3_k127_8383787_3 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000001989 145.0
EH3_k127_8383787_4 - - - - 0.00000000002355 71.0
EH3_k127_8438012_0 radical SAM K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001928 270.0
EH3_k127_8438012_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000004735 141.0
EH3_k127_8438012_2 Protein of unknown function (DUF1294) - - - 0.000000000000008505 77.0
EH3_k127_8438573_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 364.0
EH3_k127_8438573_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 340.0
EH3_k127_8438573_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000001343 227.0
EH3_k127_8438573_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000001784 176.0
EH3_k127_8438573_4 META domain - - - 0.000000000001664 72.0
EH3_k127_8438573_5 Integral membrane protein DUF106 - - - 0.000000000004022 68.0
EH3_k127_8438573_6 - - - - 0.0000006857 53.0
EH3_k127_8438573_7 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000102 55.0
EH3_k127_8467881_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 403.0
EH3_k127_8467881_1 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001115 279.0
EH3_k127_8467881_10 TIGRFAM hydrogenase maturation protease - - - 0.000000000003095 73.0
EH3_k127_8467881_11 DNA replication initiation - - - 0.0000006421 59.0
EH3_k127_8467881_12 Sigma-54 interaction domain - - - 0.0004721 51.0
EH3_k127_8467881_2 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000001019 207.0
EH3_k127_8467881_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000009481 187.0
EH3_k127_8467881_4 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000001398 168.0
EH3_k127_8467881_5 PAC2 family K06869 - - 0.000000000000000000000000000000000000000001332 166.0
EH3_k127_8467881_6 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000000001562 140.0
EH3_k127_8467881_7 Transglutaminase-like superfamily - - - 0.000000000000000000000000004409 124.0
EH3_k127_8467881_8 - - - - 0.000000000000000000000003094 111.0
EH3_k127_8467881_9 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000001264 91.0
EH3_k127_8468035_0 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000006549 78.0
EH3_k127_8468035_1 COG1522 Transcriptional regulators - - - 0.00000000002077 76.0
EH3_k127_8474880_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000001656 172.0
EH3_k127_8474880_1 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.00000000000005451 74.0
EH3_k127_8474880_2 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.0000001033 63.0
EH3_k127_8544478_0 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 402.0
EH3_k127_8544478_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000004907 188.0
EH3_k127_8544478_2 Domain of unknown function (DUF4129) - - - 0.0000000267 65.0
EH3_k127_8544478_3 Protein of unknown function DUF58 - - - 0.0000002829 57.0
EH3_k127_8544478_4 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000359 49.0
EH3_k127_857354_0 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000841 177.0
EH3_k127_857354_1 cell redox homeostasis - - - 0.00000000000002093 77.0
EH3_k127_857354_2 Phospholipid methyltransferase - - - 0.00000000000005981 78.0
EH3_k127_857354_3 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000001068 71.0
EH3_k127_857354_4 Flavin reductase like domain - - - 0.00000003015 64.0
EH3_k127_857354_5 Pathogenicity locus - - - 0.0001123 48.0
EH3_k127_8580544_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.898e-260 817.0
EH3_k127_8580544_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 538.0
EH3_k127_8580544_2 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000004985 224.0
EH3_k127_8580544_3 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000001647 138.0
EH3_k127_8580544_4 Pfam:KaiC - - - 0.000000000000001066 78.0
EH3_k127_8593473_0 PFAM Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
EH3_k127_8593473_1 O-methyltransferase activity K00588 - 2.1.1.104 0.0000000000000000000000003863 106.0
EH3_k127_8624093_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 484.0
EH3_k127_8624093_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000009584 138.0
EH3_k127_8624093_2 ABC transporter substrate-binding protein K02016 - - 0.0000000000000000000000000002439 130.0
EH3_k127_8624093_3 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000002332 110.0
EH3_k127_8624093_4 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000004443 58.0
EH3_k127_8624093_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00005735 51.0
EH3_k127_8666831_0 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000001669 250.0
EH3_k127_8666831_1 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000000000002379 232.0
EH3_k127_8666831_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000004025 224.0
EH3_k127_8666831_3 Belongs to the UPF0248 family K09715 - - 0.00000000000005456 74.0
EH3_k127_8666831_4 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000007267 59.0
EH3_k127_8688675_0 helicase superfamily c-terminal domain K05592,K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000001241 253.0
EH3_k127_8688675_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000152 105.0
EH3_k127_8688675_2 Protein involved in cellulose biosynthesis - - - 0.00003013 57.0
EH3_k127_8688675_3 SPTR Fibronectin type III domain protein - - - 0.0001929 48.0
EH3_k127_8738383_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 319.0
EH3_k127_8738383_1 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000005599 247.0
EH3_k127_8738383_2 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000001061 216.0
EH3_k127_8738383_3 - - - - 0.00000001793 61.0
EH3_k127_8760740_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 589.0
EH3_k127_8760740_1 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 295.0
EH3_k127_8760740_2 Fcf1 K07158 - - 0.000000000000000000000000000005046 123.0
EH3_k127_8760740_3 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0001411 45.0
EH3_k127_8777830_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 394.0
EH3_k127_8778978_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 426.0
EH3_k127_8778978_1 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000324 170.0
EH3_k127_8778978_2 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000006623 135.0
EH3_k127_8794279_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004311 205.0
EH3_k127_8794279_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000002785 185.0
EH3_k127_8794279_2 Pfam:DUF552 K09152 - - 0.0000000000000000000000004738 110.0
EH3_k127_8794279_3 Protein of unknown function (DUF3592) - - - 0.00000001134 64.0
EH3_k127_920240_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 308.0
EH3_k127_920240_1 4Fe-4S dicluster domain - - - 0.00000000000108 71.0
EH3_k127_920240_2 adenyl ribonucleotide binding - - - 0.000000000007246 67.0
EH3_k127_94017_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 415.0
EH3_k127_94017_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000004483 191.0
EH3_k127_94017_2 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000002846 106.0
EH3_k127_94017_3 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000697 109.0
EH3_k127_94017_4 - K06039,K07092 - - 0.00000000000000000001176 94.0
EH3_k127_94017_5 4Fe-4S dicluster domain - - - 0.0000102 49.0
EH3_k127_941274_0 Methyltransferase K08093,K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 531.0
EH3_k127_941274_1 Rad51 - - - 0.0000000000000000876 83.0
EH3_k127_941274_2 metal-dependent phosphoesterases (PHP family) - - - 0.00006729 48.0
EH3_k127_943273_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 603.0
EH3_k127_943273_1 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 298.0
EH3_k127_943273_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000001518 227.0
EH3_k127_966645_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 576.0
EH3_k127_966645_1 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000001213 265.0
EH3_k127_966645_2 pfkB family carbohydrate kinase K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000001903 244.0
EH3_k127_966645_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000004404 188.0
EH3_k127_966645_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000007011 151.0
EH3_k127_966645_5 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001069 130.0
EH3_k127_966645_6 - - - - 0.0000000000000001163 84.0
EH3_k127_966645_7 Gar1/Naf1 RNA binding region K07569 - - 0.000000007509 60.0
EH3_k127_966645_8 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0001315 44.0
EH3_k127_991031_0 Oxidoreductase NAD-binding domain K17995 - 1.12.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 342.0
EH3_k127_991031_1 4Fe-4S dicluster domain K16950 - - 0.000000000000003514 76.0